-
1
-
-
0345490853
-
A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease
-
Abbas N, Lucking CB, Ricard S, Durr A, Bonifati V, De Michele G, Bouley S, Vaughan JR, Gasser T, Marconi R, Broussolle E, Brefel-Courbon C, Harhangi BS, Oostra BA, Fabrizio E, Bohme GA, Pradier L, Wood NW, Filla A, Meco G, Denefle P, Agid Y, Brice A (1999) A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. Hum Mol Genet 8: 567-574.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 567-574
-
-
Abbas, N.1
Lucking, C.B.2
Ricard, S.3
Durr, A.4
Bonifati, V.5
de Michele, G.6
Bouley, S.7
Vaughan, J.R.8
Gasser, T.9
Marconi, R.10
Broussolle, E.11
Brefel-Courbon, C.12
Harhangi, B.S.13
Oostra, B.A.14
Fabrizio, E.15
Bohme, G.A.16
Pradier, L.17
Wood, N.W.18
Filla, A.19
Meco, G.20
Denefle, P.21
Agid, Y.22
Brice, A.23
more..
-
2
-
-
33644543761
-
Expanding insights of mitochondrial dysfunction in Parkinson's disease
-
Abou-Sleiman PM, Muqit MM, Wood NW (2006) Expanding insights of mitochondrial dysfunction in Parkinson's disease. Nat Rev Neurosci 7: 207-219.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 207-219
-
-
Abou-Sleiman, P.M.1
Muqit, M.M.2
Wood, N.W.3
-
3
-
-
0037443884
-
Human mitochondrial DNA is packaged with TFAM
-
Alam TI, Kanki T, Muta T, Ukaji K, Abe Y, Nakayama H, Takio K, Hamasaki N, Kang D (2003) Human mitochondrial DNA is packaged with TFAM. Nucleic Acids Res 31: 1640-1645.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 1640-1645
-
-
Alam, T.I.1
Kanki, T.2
Muta, T.3
Ukaji, K.4
Abe, Y.5
Nakayama, H.6
Takio, K.7
Hamasaki, N.8
Kang, D.9
-
4
-
-
0024978377
-
Heat shock protein-mediated disassembly of nucleoprotein structures is required for the initiation of bacteriophage lambda DNA replication
-
Alfano C, McMacken R (1989) Heat shock protein-mediated disassembly of nucleoprotein structures is required for the initiation of bacteriophage lambda DNA replication. J Biol Chem 264: 10709-10718.
-
(1989)
J Biol Chem
, vol.264
, pp. 10709-10718
-
-
Alfano, C.1
McMacken, R.2
-
5
-
-
47849097951
-
Mitochondrial transcription factor A (TFAM) gene variation and risk of late-onset Alzheimer's disease
-
Alvarez V, Corao AI, Alonso-Montes C, Sanchez-Ferrero E, De Mena L, Morales B, Garcia-Castro M, Coto E (2008) Mitochondrial transcription factor A (TFAM) gene variation and risk of late-onset Alzheimer's disease. J Alzheimers Dis 13: 275-280.
-
(2008)
J Alzheimers Dis
, vol.13
, pp. 275-280
-
-
Alvarez, V.1
Corao, A.I.2
Alonso-Montes, C.3
Sanchez-Ferrero, E.4
de Mena, L.5
Morales, B.6
Garcia-Castro, M.7
Coto, E.8
-
6
-
-
0033563018
-
Quantitation and origin of the mitochondrial membrane potential in human cells lacking mitochondrial DNA
-
Appleby RD, Porteous WK, Hughes G, James AM, Shannon D, Wei YH, Murphy MP (1999) Quantitation and origin of the mitochondrial membrane potential in human cells lacking mitochondrial DNA. Eur J Biochem 262: 108-116.
-
(1999)
Eur J Biochem
, vol.262
, pp. 108-116
-
-
Appleby, R.D.1
Porteous, W.K.2
Hughes, G.3
James, A.M.4
Shannon, D.5
Wei, Y.H.6
Murphy, M.P.7
-
7
-
-
77954353059
-
Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: Possible direct function in mitochondrial biogenesis
-
Aquilano K, Vigilanza P, Baldelli S, Pagliei B, Rotilio G, Ciriolo MR (2010) Peroxisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha) and sirtuin 1 (SIRT1) reside in mitochondria: possible direct function in mitochondrial biogenesis. J Biol Chem 285: 21590-21599.
-
(2010)
J Biol Chem
, vol.285
, pp. 21590-21599
-
-
Aquilano, K.1
Vigilanza, P.2
Baldelli, S.3
Pagliei, B.4
Rotilio, G.5
Ciriolo, M.R.6
-
8
-
-
78349313801
-
Integrating multiple aspects of mitochondrial dynamics in neurons: Age-related differences and dynamic changes in a chronic rotenone model
-
Arnold B, Cassady SJ, VanLaar VS, Berman SB (2011) Integrating multiple aspects of mitochondrial dynamics in neurons: age-related differences and dynamic changes in a chronic rotenone model. Neurobiol Dis 41: 189-200.
-
(2011)
Neurobiol Dis
, vol.41
, pp. 189-200
-
-
Arnold, B.1
Cassady, S.J.2
Vanlaar, V.S.3
Berman, S.B.4
-
9
-
-
34447249263
-
Familial parkinsonism and ophthalmoplegia from a mutation in the mitochondrial DNA helicase twinkle
-
Baloh RH, Salavaggione E, Milbrandt J, Pestronk A (2007) Familial parkinsonism and ophthalmoplegia from a mutation in the mitochondrial DNA helicase twinkle. Arch Neurol 64: 998-1000.
-
(2007)
Arch Neurol
, vol.64
, pp. 998-1000
-
-
Baloh, R.H.1
Salavaggione, E.2
Milbrandt, J.3
Pestronk, A.4
-
10
-
-
33646375711
-
High levels of mito chondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender A, Krishnan KJ, Morris CM, Taylor GA, Reeve AK, Perry RH, Jaros E, Hersheson JS, Betts J, Klopstock T, Taylor RW, Turnbull DM (2006) High levels of mito chondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat Genet 38: 515-517.
-
(2006)
Nat Genet
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
Taylor, R.W.11
Turnbull, D.M.12
-
11
-
-
67549146854
-
Frequency of heterozygous Parkin mutations in healthy subjects: Need for careful prospective follow-up examination of mutation carriers
-
Bruggemann N, Mitterer M, Lanthaler AJ, Djarmati A, Hagenah J, Wiegers K, Winkler S, Pawlack H, Lohnau T, Pramstaller PP, Klein C, Lohmann K (2009) Frequency of heterozygous Parkin mutations in healthy subjects: need for careful prospective follow-up examination of mutation carriers. Parkinsonism Relat Disord 15: 425-429.
-
(2009)
Parkinsonism Relat Disord
, vol.15
, pp. 425-429
-
-
Bruggemann, N.1
Mitterer, M.2
Lanthaler, A.J.3
Djarmati, A.4
Hagenah, J.5
Wiegers, K.6
Winkler, S.7
Pawlack, H.8
Lohnau, T.9
Pramstaller, P.P.10
Klein, C.11
Lohmann, K.12
-
12
-
-
0032483497
-
Functional F1-ATPase essential in maintaining growth and membrane potential of human mitochondrial DNA-depleted rho degrees cells
-
Buchet K, Godinot C (1998) Functional F1-ATPase essential in maintaining growth and membrane potential of human mitochondrial DNA-depleted rho degrees cells. J Biol Chem 273: 22983-22989.
-
(1998)
J Biol Chem
, vol.273
, pp. 22983-22989
-
-
Buchet, K.1
Godinot, C.2
-
13
-
-
77958479016
-
Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: Functional impact of diseaserelated variants on mitochondrial homeostasis
-
Burbulla LF, Schelling C, Kato H, Rapaport D, Woitalla D, Schiesling C, Schulte C, Sharma M, Illig T, Bauer P, Jung S, Nordheim A, Schols L, Riess O, Kruger R (2010) Dissecting the role of the mitochondrial chaperone mortalin in Parkinson's disease: functional impact of diseaserelated variants on mitochondrial homeostasis. Hum Mol Genet 19: 4437-4452.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4437-4452
-
-
Burbulla, L.F.1
Schelling, C.2
Kato, H.3
Rapaport, D.4
Woitalla, D.5
Schiesling, C.6
Schulte, C.7
Sharma, M.8
Illig, T.9
Bauer, P.10
Jung, S.11
Nordheim, A.12
Schols, L.13
Riess, O.14
Kruger, R.15
-
14
-
-
84862986470
-
Analysis of neural subtypes reveals selective mitochondrial dysfunction in dopaminergic neurons from parkin mutants
-
Burman JL, Yu S, Poole AC, Decal RB, Pallanck L (2012) Analysis of neural subtypes reveals selective mitochondrial dysfunction in dopaminergic neurons from parkin mutants. Proc Natl Acad Sci U S A 109: 10438-10443.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 10438-10443
-
-
Burman, J.L.1
Yu, S.2
Poole, A.C.3
Decal, R.B.4
Pallanck, L.5
-
15
-
-
84864873195
-
Long time-lapse imaging reveals unique features of PARK2/Parkinmediated mitophagy in mature cortical neurons
-
Cai Q, Zakaria HM, Sheng ZH (2012a) Long time-lapse imaging reveals unique features of PARK2/Parkinmediated mitophagy in mature cortical neurons. Autophagy 8: 976-978.
-
(2012)
Autophagy
, vol.8
, pp. 976-978
-
-
Cai, Q.1
Zakaria, H.M.2
Sheng, Z.H.3
-
16
-
-
84858701257
-
Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons
-
Cai Q, Zakaria HM, Simone A, Sheng ZH (2012b) Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons. Curr Biol 22: 545-552.
-
(2012)
Curr Biol
, vol.22
, pp. 545-552
-
-
Cai, Q.1
Zakaria, H.M.2
Simone, A.3
Sheng, Z.H.4
-
17
-
-
84864293013
-
Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number
-
Campbell CT, Kolesar JE, Kaufman BA (2012) Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number. Biochim Biophys Acta 1819: 921-929.
-
(2012)
Biochim Biophys Acta
, pp. 921-929
-
-
Campbell, C.T.1
Kolesar, J.E.2
Kaufman, B.A.3
-
18
-
-
84861306914
-
Microtubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts
-
Cartelli D, Goldwurm S, Casagrande F, Pezzoli G, Cappelletti G (2012) Microtubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts. PLoS One 7: e37467.
-
(2012)
PLoS One
, vol.7
-
-
Cartelli, D.1
Goldwurm, S.2
Casagrande, F.3
Pezzoli, G.4
Cappelletti, G.5
-
19
-
-
79960649509
-
Autoregulation of Parkin activity through its ubiquitin-like domain
-
Chaugule VK, Burchell L, Barber KR, Sidhu A, Leslie SJ, Shaw GS, Walden H (2011) Autoregulation of Parkin activity through its ubiquitin-like domain. EMBO J 30: 2853-2867.
-
(2011)
EMBO J
, vol.30
, pp. 2853-2867
-
-
Chaugule, V.K.1
Burchell, L.2
Barber, K.R.3
Sidhu, A.4
Leslie, S.J.5
Shaw, G.S.6
Walden, H.7
-
20
-
-
78649653044
-
Parkin mono-ubiquitinates Bcl-2 and regulates autophagy
-
Chen D, Gao F, Li B, Wang H, Xu Y, Zhu C, Wang G (2010) Parkin mono-ubiquitinates Bcl-2 and regulates autophagy. J Biol Chem 285: 38214-38223.
-
(2010)
J Biol Chem
, vol.285
, pp. 38214-38223
-
-
Chen, D.1
Gao, F.2
Li, B.3
Wang, H.4
Xu, Y.5
Zhu, C.6
Wang, G.7
-
21
-
-
0024972083
-
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria
-
Cheng MY, Hartl FU, Martin J, Pollock RA, Kalousek F, Neupert W, Hallberg EM, Hallberg RL, Horwich AL (1989) Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria. Nature 337: 620-625.
-
(1989)
Nature
, vol.337
, pp. 620-625
-
-
Cheng, M.Y.1
Hartl, F.U.2
Martin, J.3
Pollock, R.A.4
Kalousek, F.5
Neupert, W.6
Hallberg, E.M.7
Hallberg, R.L.8
Horwich, A.L.9
-
22
-
-
79957517961
-
Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination
-
Chew KC, Matsuda N, Saisho K, Lim GG, Chai C, Tan HM, Tanaka K, Lim KL (2011) Parkin mediates apparent E2-independent monoubiquitination in vitro and contains an intrinsic activity that catalyzes polyubiquitination. PLoS One 6: e19720.
-
(2011)
PLoS One
, vol.6
-
-
Chew, K.C.1
Matsuda, N.2
Saisho, K.3
Lim, G.G.4
Chai, C.5
Tan, H.M.6
Tanaka, K.7
Lim, K.L.8
-
23
-
-
79961207065
-
Mortalin inhibition in experimental Parkinson's disease
-
Chiasserini D, Tozzi A, de Iure A, Tantucci M, Susta F, Orvietani PL, Koya K, Binaglia L, Calabresi P (2011) Mortalin inhibition in experimental Parkinson's disease. Mov Disord 26: 1639-1647.
-
(2011)
Mov Disord
, vol.26
, pp. 1639-1647
-
-
Chiasserini, D.1
Tozzi, A.2
de Iure, A.3
Tantucci, M.4
Susta, F.5
Orvietani, P.L.6
Koya, K.7
Binaglia, L.8
Calabresi, P.9
-
24
-
-
2542534741
-
S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function
-
Chung KK, Thomas B, Li X, Pletnikova O, Troncoso JC, Marsh L, Dawson VL, Dawson TM (2004) S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function. Science 304: 1328-1331.
-
(2004)
Science
, vol.304
, pp. 1328-1331
-
-
Chung, K.K.1
Thomas, B.2
Li, X.3
Pletnikova, O.4
Troncoso, J.C.5
Marsh, L.6
Dawson, V.L.7
Dawson, T.M.8
-
25
-
-
84859242538
-
Sustained expression of PGC-1alpha in the rat nigrostriatal system selectively impairs dopaminergic function
-
Ciron C, Lengacher S, Dusonchet J, Aebischer P, Schneider BL (2012) Sustained expression of PGC-1alpha in the rat nigrostriatal system selectively impairs dopaminergic function. Hum Mol Genet 21: 1861-1876.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 1861-1876
-
-
Ciron, C.1
Lengacher, S.2
Dusonchet, J.3
Aebischer, P.4
Schneider, B.L.5
-
26
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M (2006) Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441: 1162-1166.
-
(2006)
Nature
, vol.441
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
27
-
-
79955994007
-
Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease
-
Clark J, Reddy S, Zheng K, Betensky RA, Simon DK (2011) Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease. BMC Med Genet 12: 69.
-
(2011)
BMC Med Genet
, vol.12
, pp. 69
-
-
Clark, J.1
Reddy, S.2
Zheng, K.3
Betensky, R.A.4
Simon, D.K.5
-
28
-
-
51149083921
-
Electrophysiology and pharmacology of striatal neuronal dysfunction induced by mitochondrial complex I inhibition
-
Costa C, Belcastro V, Tozzi A, Di Filippo M, Tantucci M, Siliquini S, Autuori A, Picconi B, Spillantini MG, Fedele E, Pittaluga A, Raiteri M, Calabresi P (2008) Electrophysiology and pharmacology of striatal neuronal dysfunction induced by mitochondrial complex I inhibition. J Neurosci 28: 8040-8052.
-
(2008)
J Neurosci
, vol.28
, pp. 8040-8052
-
-
Costa, C.1
Belcastro, V.2
Tozzi, A.3
Di Filippo, M.4
Tantucci, M.5
Siliquini, S.6
Autuori, A.7
Picconi, B.8
Spillantini, M.G.9
Fedele, E.10
Pittaluga, A.11
Raiteri, M.12
Calabresi, P.13
-
29
-
-
70449519412
-
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease
-
da Costa CA, Sunyach C, Giaime E, West A, Corti O, Brice A, Safe S, Abou-Sleiman PM, Wood NW, Takahashi H, Goldberg MS, Shen J, Checler F (2009) Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. Nat Cell Biol 11: 1370-1375.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1370-1375
-
-
da Costa, C.A.1
Sunyach, C.2
Giaime, E.3
West, A.4
Corti, O.5
Brice, A.6
Safe, S.7
Abou-Sleiman, P.M.8
Wood, N.W.9
Takahashi, H.10
Goldberg, M.S.11
Shen, J.12
Checler, F.13
-
30
-
-
67649399288
-
Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission
-
Dagda RK, Cherra SJ, 3rd, Kulich SM, Tandon A, Park D, Chu CT (2009) Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission. J Biol Chem 284: 13843-13855.
-
(2009)
J Biol Chem
, vol.284
, pp. 13843-13855
-
-
Dagda, R.K.1
Cherra III, S.J.2
Kulich, S.M.3
Tandon, A.4
Park, D.5
Chu, C.T.6
-
31
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
Darios F, Corti O, Lucking CB, Hampe C, Muriel MP, Abbas N, Gu WJ, Hirsch EC, Rooney T, Ruberg M, Brice A (2003) Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Hum Mol Genet 12: 517-526.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
Lucking, C.B.3
Hampe, C.4
Muriel, M.P.5
Abbas, N.6
Gu, W.J.7
Hirsch, E.C.8
Rooney, T.9
Ruberg, M.10
Brice, A.11
-
32
-
-
70349150536
-
Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function
-
Davison EJ, Pennington K, Hung CC, Peng J, Rafiq R, Ostareck-Lederer A, Ostareck DH, Ardley HC, Banks RE, Robinson PA (2009) Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function. Proteomics 9: 4284-4297.
-
(2009)
Proteomics
, vol.9
, pp. 4284-4297
-
-
Davison, E.J.1
Pennington, K.2
Hung, C.C.3
Peng, J.4
Rafiq, R.5
Ostareck-Lederer, A.6
Ostareck, D.H.7
Ardley, H.C.8
Banks, R.E.9
Robinson, P.A.10
-
33
-
-
77953424577
-
The role of parkin in familial and sporadic Parkinson's disease
-
Dawson TM, Dawson VL (2010) The role of parkin in familial and sporadic Parkinson's disease. Mov Disord 25 Suppl 1: S32-39.
-
(2010)
Mov Disord
, vol.25
, Issue.SUPPL. 1
-
-
Dawson, T.M.1
Dawson, V.L.2
-
34
-
-
77953666105
-
Genetic animal models of Parkinson's disease
-
Dawson TM, Ko HS, Dawson VL (2010) Genetic animal models of Parkinson's disease. Neuron 66: 646-661.
-
(2010)
Neuron
, vol.66
, pp. 646-661
-
-
Dawson, T.M.1
Ko, H.S.2
Dawson, V.L.3
-
35
-
-
70349238601
-
Mutational screening of the mortalin gene (HSPA9) in Parkinson's disease
-
De Mena L, Coto E, Sanchez-Ferrero E, Ribacoba R, Guisasola LM, Salvador C, Blazquez M, Alvarez V (2009) Mutational screening of the mortalin gene (HSPA9) in Parkinson's disease. J Neural Transm 116: 1289-1293.
-
(2009)
J Neural Transm
, vol.116
, pp. 1289-1293
-
-
de Mena, L.1
Coto, E.2
Sanchez-Ferrero, E.3
Ribacoba, R.4
Guisasola, L.M.5
Salvador, C.6
Blazquez, M.7
Alvarez, V.8
-
37
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
Deng H, Dodson MW, Huang H, Guo M (2008) The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc Natl Acad Sci U S A 105: 14503-14508.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
38
-
-
33745475570
-
On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60
-
Deocaris CC, Kaul SC, Wadhwa R (2006) On the brotherhood of the mitochondrial chaperones mortalin and heat shock protein 60. Cell Stress Chaperones 11: 116-128.
-
(2006)
Cell Stress Chaperones
, vol.11
, pp. 116-128
-
-
Deocaris, C.C.1
Kaul, S.C.2
Wadhwa, R.3
-
39
-
-
35448960851
-
Functions and dysfunctions of mitochondrial dynamics
-
Detmer SA, Chan DC (2007) Functions and dysfunctions of mitochondrial dynamics. Nat Rev Mol Cell Biol 8: 870-879.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 870-879
-
-
Detmer, S.A.1
Chan, D.C.2
-
40
-
-
20444450523
-
Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains
-
Doss-Pepe EW, Chen L, Madura K (2005) Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains. J Biol Chem 280: 16619-16624.
-
(2005)
J Biol Chem
, vol.280
, pp. 16619-16624
-
-
Doss-Pepe, E.W.1
Chen, L.2
Madura, K.3
-
41
-
-
0037016687
-
Parkin and CASK/LIN-2 associate via a PDZmediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain
-
Fallon L, Moreau F, Croft BG, Labib N, Gu WJ, Fon EA (2002) Parkin and CASK/LIN-2 associate via a PDZmediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. J Biol Chem 277: 486-491.
-
(2002)
J Biol Chem
, vol.277
, pp. 486-491
-
-
Fallon, L.1
Moreau, F.2
Croft, B.G.3
Labib, N.4
Gu, W.J.5
Fon, E.A.6
-
42
-
-
33746594215
-
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
-
Fallon L, Belanger CM, Corera AT, Kontogiannea M, Regan-Klapisz E, Moreau F, Voortman J, Haber M, Rouleau G, Thorarinsdottir T, Brice A, van Bergen En Henegouwen PM, Fon EA (2006) A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nat Cell Biol 8: 834-842.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 834-842
-
-
Fallon, L.1
Belanger, C.M.2
Corera, A.T.3
Kontogiannea, M.4
Regan-Klapisz, E.5
Moreau, F.6
Voortman, J.7
Haber, M.8
Rouleau, G.9
Thorarinsdottir, T.10
Brice, A.11
van Bergen, E.H.P.M.12
Fon, E.A.13
-
43
-
-
0034848395
-
Lewy bodies and parkinsonism in families with parkin mutations
-
Farrer M, Chan P, Chen R, Tan L, Lincoln S, Hernandez D, Forno L, Gwinn-Hardy K, Petrucelli L, Hussey J, Singleton A, Tanner C, Hardy J, Langston JW (2001) Lewy bodies and parkinsonism in families with parkin mutations. Ann Neurol 50: 293-300.
-
(2001)
Ann Neurol
, vol.50
, pp. 293-300
-
-
Farrer, M.1
Chan, P.2
Chen, R.3
Tan, L.4
Lincoln, S.5
Hernandez, D.6
Forno, L.7
Gwinn-Hardy, K.8
Petrucelli, L.9
Hussey, J.10
Singleton, A.11
Tanner, C.12
Hardy, J.13
Langston, J.W.14
-
44
-
-
58149149970
-
Parkin deficiency increases vulnerability to inflammation-related nigral degeneration
-
Frank-Cannon TC, Tran T, Ruhn KA, Martinez TN, Hong J, Marvin M, Hartley M, Trevino I, O'Brien DE, Casey B, Goldberg MS, Tansey MG (2008) Parkin deficiency increases vulnerability to inflammation-related nigral degeneration. J Neurosci 28: 10825-10834.
-
(2008)
J Neurosci
, vol.28
, pp. 10825-10834
-
-
Frank-Cannon, T.C.1
Tran, T.2
Ruhn, K.A.3
Martinez, T.N.4
Hong, J.5
Marvin, M.6
Hartley, M.7
Trevino, I.8
O'Brien, D.E.9
Casey, B.10
Goldberg, M.S.11
Tansey, M.G.12
-
45
-
-
0037458579
-
Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis
-
Fransson A, Ruusala A, Aspenstrom P (2003) Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. J Biol Chem 278: 6495-6502.
-
(2003)
J Biol Chem
, vol.278
, pp. 6495-6502
-
-
Fransson, A.1
Ruusala, A.2
Aspenstrom, P.3
-
46
-
-
49649097747
-
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
Gautier CA, Kitada T, Shen J (2008) Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress. Proc Natl Acad Sci U S A 105: 11364-11369.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
47
-
-
72649095199
-
Mitochondrial transcription factor A variants and the risk of Parkinson's disease
-
Gaweda-Walerych K, Safranow K, Maruszak A, Bialecka M, Klodowska-Duda G, Czyzewski K, Slawek J, Rudzinska M, Styczynska M, Opala G, Drozdzik M, Kurzawski M, Szczudlik A, Canter JA, Barcikowska M, Zekanowski C (2010) Mitochondrial transcription factor A variants and the risk of Parkinson's disease. Neurosci Lett 469: 24-29.
-
(2010)
Neurosci Lett
, vol.469
, pp. 24-29
-
-
Gaweda-Walerych, K.1
Safranow, K.2
Maruszak, A.3
Bialecka, M.4
Klodowska-Duda, G.5
Czyzewski, K.6
Slawek, J.7
Rudzinska, M.8
Styczynska, M.9
Opala, G.10
Drozdzik, M.11
Kurzawski, M.12
Szczudlik, A.13
Canter, J.A.14
Barcikowska, M.15
Zekanowski, C.16
-
48
-
-
84879728471
-
Overexpressed parkin increases mitochondrial DNA transcription and replication, independently of mitochondrial transcription factor A (TFAM) protein level
-
(in press), Alzheimer's and Parkinson's Diseases: Mechanisms, Clinical Strategies, and Promising Treatments of Neurodegenerative Diseases (The 11th International Conference On Alzheimer's & Parkinson's Diseases). Neurodegenerative Diseases
-
Gaweda-Walerych K, Zekanowski C (2013) Overexpressed parkin increases mitochondrial DNA transcription and replication, independently of mitochondrial transcription factor A (TFAM) protein level. In: Alzheimer's and Parkinson's Diseases: Mechanisms, Clinical Strategies, and Promising Treatments of Neurodegenerative Diseases (The 11th International Conference on Alzheimer's & Parkinson's Diseases). Neurodegenerative Diseases vol. 11 (Suppl. 1) (in press)
-
(2013)
, vol.11
, Issue.SUPPL. 1
-
-
Gaweda-Walerych, K.1
Zekanowski, C.2
-
49
-
-
78649463381
-
Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
-
Gegg ME, Cooper JM, Chau KY, Rojo M, Schapira AH, Taanman JW (2010) Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy. Hum Mol Genet 19: 4861-4870.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4861-4870
-
-
Gegg, M.E.1
Cooper, J.M.2
Chau, K.Y.3
Rojo, M.4
Schapira, A.H.5
Taanman, J.W.6
-
50
-
-
75949130828
-
PINK1/Parkinmediated mitophagy is dependent on VDAC1 and p62/ SQSTM1
-
Geisler S, Holmstrom KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W (2010a) PINK1/Parkinmediated mitophagy is dependent on VDAC1 and p62/ SQSTM1. Nat Cell Biol 12: 119-131.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
51
-
-
77957673363
-
The PINK1/ Parkin-mediated mitophagy is compromised by PD-associated mutations
-
Geisler S, Holmstrom KM, Treis A, Skujat D, Weber SS, Fiesel FC, Kahle PJ, Springer W (2010b) The PINK1/ Parkin-mediated mitophagy is compromised by PD-associated mutations. Autophagy 6: 871-878.
-
(2010)
Autophagy
, vol.6
, pp. 871-878
-
-
Geisler, S.1
Holmstrom, K.M.2
Treis, A.3
Skujat, D.4
Weber, S.S.5
Fiesel, F.C.6
Kahle, P.J.7
Springer, W.8
-
52
-
-
84856951239
-
Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition
-
Gilkerson RW, De Vries RL, Lebot P, Wikstrom JD, Torgyekes E, Shirihai OS, Przedborski S, Schon EA (2012) Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition. Hum Mol Genet 21: 978-990.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 978-990
-
-
Gilkerson, R.W.1
de Vries, R.L.2
Lebot, P.3
Wikstrom, J.D.4
Torgyekes, E.5
Shirihai, O.S.6
Przedborski, S.7
Schon, E.A.8
-
53
-
-
66749163493
-
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration
-
Gispert S, Ricciardi F, Kurz A, Azizov M, Hoepken HH, Becker D, Voos W, Leuner K, Muller WE, Kudin AP, Kunz WS, Zimmermann A, Roeper J, Wenzel D, Jendrach M, Garcia-Arencibia M, Fernandez-Ruiz J, Huber L, Rohrer H, Barrera M, Reichert AS, Rub U, Chen A, Nussbaum RL, Auburger G (2009) Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. PLoS One 4: e5777.
-
(2009)
PLoS One
, vol.4
-
-
Gispert, S.1
Ricciardi, F.2
Kurz, A.3
Azizov, M.4
Hoepken, H.H.5
Becker, D.6
Voos, W.7
Leuner, K.8
Muller, W.E.9
Kudin, A.P.10
Kunz, W.S.11
Zimmermann, A.12
Roeper, J.13
Wenzel, D.14
Jendrach, M.15
Garcia-Arencibia, M.16
Fernandez-Ruiz, J.17
Huber, L.18
Rohrer, H.19
Barrera, M.20
Reichert, A.S.21
Rub, U.22
Chen, A.23
Nussbaum, R.L.24
Auburger, G.25
more..
-
54
-
-
79960493052
-
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1
-
Glauser L, Sonnay S, Stafa K, Moore DJ (2011) Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. J Neurochem 118: 636-645.
-
(2011)
J Neurochem
, vol.118
, pp. 636-645
-
-
Glauser, L.1
Sonnay, S.2
Stafa, K.3
Moore, D.J.4
-
55
-
-
81155123695
-
PGC-1-related coactivator (PRC), a sensor of metabolic stress, orchestrates a redoxsensitive program of inflammatory gene expression
-
Gleyzer N, Scarpulla RC (2011) PGC-1-related coactivator (PRC), a sensor of metabolic stress, orchestrates a redoxsensitive program of inflammatory gene expression. J Biol Chem 286: 39715-39725.
-
(2011)
J Biol Chem
, vol.286
, pp. 39715-39725
-
-
Gleyzer, N.1
Scarpulla, R.C.2
-
56
-
-
58149163606
-
Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling
-
Goffart S, Cooper HM, Tyynismaa H, Wanrooij S, Suomalainen A, Spelbrink JN (2009) Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling. Hum Mol Genet 18: 328-340.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 328-340
-
-
Goffart, S.1
Cooper, H.M.2
Tyynismaa, H.3
Wanrooij, S.4
Suomalainen, A.5
Spelbrink, J.N.6
-
57
-
-
77951587107
-
Mitochondrial and nuclear genomic responses to loss of LRPPRC expression
-
Gohil VM, Nilsson R, Belcher-Timme CA, Luo B, Root DE, Mootha VK (2010) Mitochondrial and nuclear genomic responses to loss of LRPPRC expression. J Biol Chem 285: 13742-13747.
-
(2010)
J Biol Chem
, vol.285
, pp. 13742-13747
-
-
Gohil, V.M.1
Nilsson, R.2
Belcher-Timme, C.A.3
Luo, B.4
Root, D.E.5
Mootha, V.K.6
-
58
-
-
0141891953
-
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
-
Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, Bhatnagar A, Meloni EG, Wu N, Ackerson LC, Klapstein GJ, Gajendiran M, Roth BL, Chesselet MF, Maidment NT, Levine MS, Shen J (2003) Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J Biol Chem 278: 43628-43635.
-
(2003)
J Biol Chem
, vol.278
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepeda, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
Gajendiran, M.11
Roth, B.L.12
Chesselet, M.F.13
Maidment, N.T.14
Levine, M.S.15
Shen, J.16
-
59
-
-
0038699003
-
Autosomal recessive parkinsonism linked to parkin gene in a Tunisian family. Clinical, genetic and pathological study
-
Gouider-Khouja N, Larnaout A, Amouri R, Sfar S, Belal S, Ben Hamida C, Ben Hamida M, Hattori N, Mizuno Y, Hentati F (2003) Autosomal recessive parkinsonism linked to parkin gene in a Tunisian family. Clinical, genetic and pathological study. Parkinsonism Relat Disord 9: 247-251.
-
(2003)
Parkinsonism Relat Disord
, vol.9
, pp. 247-251
-
-
Gouider-Khouja, N.1
Larnaout, A.2
Amouri, R.3
Sfar, S.4
Belal, S.5
Ben Hamida, C.6
Ben Hamida, M.7
Hattori, N.8
Mizuno, Y.9
Hentati, F.10
-
60
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ (2003) Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci U S A 100: 4078-4083.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
61
-
-
15544380902
-
Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis
-
Greene JC, Whitworth AJ, Andrews LA, Parker TJ, Pallanck LJ (2005) Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis. Hum Mol Genet 14: 799-811.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 799-811
-
-
Greene, J.C.1
Whitworth, A.J.2
Andrews, L.A.3
Parker, T.J.4
Pallanck, L.J.5
-
62
-
-
68549136513
-
Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology
-
Grunewald A, Gegg ME, Taanman JW, King RH, Kock N, Klein C, Schapira AH (2009) Differential effects of PINK1 nonsense and missense mutations on mitochondrial function and morphology. Exp Neurol 219: 266-273.
-
(2009)
Exp Neurol
, vol.219
, pp. 266-273
-
-
Grunewald, A.1
Gegg, M.E.2
Taanman, J.W.3
King, R.H.4
Kock, N.5
Klein, C.6
Schapira, A.H.7
-
63
-
-
23044432581
-
The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses
-
Guo X, Macleod GT, Wellington A, Hu F, Panchumarthi S, Schoenfield M, Marin L, Charlton MP, Atwood HL, Zinsmaier KE (2005) The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses. Neuron 47: 379-393.
-
(2005)
Neuron
, vol.47
, pp. 379-393
-
-
Guo, X.1
Macleod, G.T.2
Wellington, A.3
Hu, F.4
Panchumarthi, S.5
Schoenfield, M.6
Marin, L.7
Charlton, M.P.8
Atwood, H.L.9
Zinsmaier, K.E.10
-
64
-
-
36148995473
-
Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alleles
-
Hagenah JM, Konig IR, Becker B, Hilker R, Kasten M, Hedrich K, Pramstaller PP, Klein C, Seidel G (2007) Substantia nigra hyperechogenicity correlates with clinical status and number of Parkin mutated alleles. J Neurol 254: 1407-1413.
-
(2007)
J Neurol
, vol.254
, pp. 1407-1413
-
-
Hagenah, J.M.1
Konig, I.R.2
Becker, B.3
Hilker, R.4
Kasten, M.5
Hedrich, K.6
Pramstaller, P.P.7
Klein, C.8
Seidel, G.9
-
65
-
-
33745280651
-
Biochemical analysis of Parkinson's diseasecausing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity
-
Hampe C, Ardila-Osorio H, Fournier M, Brice A, Corti O (2006) Biochemical analysis of Parkinson's diseasecausing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. Hum Mol Genet 15: 2059-2075.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 2059-2075
-
-
Hampe, C.1
Ardila-Osorio, H.2
Fournier, M.3
Brice, A.4
Corti, O.5
-
66
-
-
18244412384
-
Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals
-
Hattori N, Kitada T, Matsumine H, Asakawa S, Yamamura Y, Yoshino H, Kobayashi T, Yokochi M, Wang M, Yoritaka A, Kondo T, Kuzuhara S, Nakamura S, Shimizu N, Mizuno Y (1998) Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals. Ann Neurol 44: 935-941.
-
(1998)
Ann Neurol
, vol.44
, pp. 935-941
-
-
Hattori, N.1
Kitada, T.2
Matsumine, H.3
Asakawa, S.4
Yamamura, Y.5
Yoshino, H.6
Kobayashi, T.7
Yokochi, M.8
Wang, M.9
Yoritaka, A.10
Kondo, T.11
Kuzuhara, S.12
Nakamura, S.13
Shimizu, N.14
Mizuno, Y.15
-
67
-
-
0033814671
-
An autopsy case of autosomal-recessive juvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene
-
Hayashi S, Wakabayashi K, Ishikawa A, Nagai H, Saito M, Maruyama M, Takahashi T, Ozawa T, Tsuji S, Takahashi H (2000) An autopsy case of autosomal-recessive juvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene. Mov Disord 15: 884-888.
-
(2000)
Mov Disord
, vol.15
, pp. 884-888
-
-
Hayashi, S.1
Wakabayashi, K.2
Ishikawa, A.3
Nagai, H.4
Saito, M.5
Maruyama, M.6
Takahashi, T.7
Ozawa, T.8
Tsuji, S.9
Takahashi, H.10
-
68
-
-
51649126499
-
Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice
-
Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi- Shindou M, Kanki T, Kang D, Sunagawa K, Tsutsui H, Nakanishi H (2008) Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor a in mice. J Neurosci 28: 8624-8634.
-
(2008)
J Neurosci
, vol.28
, pp. 8624-8634
-
-
Hayashi, Y.1
Yoshida, M.2
Yamato, M.3
Ide, T.4
Wu, Z.5
Ochi-Shindou, M.6
Kanki, T.7
Kang, D.8
Sunagawa, K.9
Tsutsui, H.10
Nakanishi, H.11
-
69
-
-
39149102870
-
Stimulation of mitochondrial biogenesis and autophagy by lipopolysaccharide in the neonatal rat cardiomyocyte protects against programmed cell death
-
Hickson-Bick DL, Jones C, Buja LM (2008) Stimulation of mitochondrial biogenesis and autophagy by lipopolysaccharide in the neonatal rat cardiomyocyte protects against programmed cell death. J Mol Cell Cardiol 44: 411-418.
-
(2008)
J Mol Cell Cardiol
, vol.44
, pp. 411-418
-
-
Hickson-Bick, D.L.1
Jones, C.2
Buja, L.M.3
-
70
-
-
0035096967
-
Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene
-
Hilker R, Klein C, Ghaemi M, Kis B, Strotmann T, Ozelius LJ, Lenz O, Vieregge P, Herholz K, Heiss WD, Pramstaller PP (2001) Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene. Ann Neurol 49: 367-376.
-
(2001)
Ann Neurol
, vol.49
, pp. 367-376
-
-
Hilker, R.1
Klein, C.2
Ghaemi, M.3
Kis, B.4
Strotmann, T.5
Ozelius, L.J.6
Lenz, O.7
Vieregge, P.8
Herholz, K.9
Heiss, W.D.10
Pramstaller, P.P.11
-
71
-
-
0037134095
-
The striatal dopaminergic deficit is dependent on the number of mutant alleles in a family with mutations in the parkin gene: Evidence for enzymatic parkin function in humans
-
Hilker R, Klein C, Hedrich K, Ozelius LJ, Vieregge P, Herholz K, Pramstaller PP, Heiss WD (2002) The striatal dopaminergic deficit is dependent on the number of mutant alleles in a family with mutations in the parkin gene: evidence for enzymatic parkin function in humans. Neurosci Lett 323: 50-54.
-
(2002)
Neurosci Lett
, vol.323
, pp. 50-54
-
-
Hilker, R.1
Klein, C.2
Hedrich, K.3
Ozelius, L.J.4
Vieregge, P.5
Herholz, K.6
Pramstaller, P.P.7
Heiss, W.D.8
-
72
-
-
0032559260
-
Kinesin and dynein superfamily proteins and the mechanism of organelle transport
-
Hirokawa N (1998) Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 279: 519-526.
-
(1998)
Science
, vol.279
, pp. 519-526
-
-
Hirokawa, N.1
-
73
-
-
33846288002
-
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6
-
Hoepken HH, Gispert S, Morales B, Wingerter O, Del Turco D, Mulsch A, Nussbaum RL, Muller K, Drose S, Brandt U, Deller T, Wirth B, Kudin AP, Kunz WS, Auburger G (2007) Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. Neurobiol Dis 25: 401-411.
-
(2007)
Neurobiol Dis
, vol.25
, pp. 401-411
-
-
Hoepken, H.H.1
Gispert, S.2
Morales, B.3
Wingerter, O.4
Del Turco, D.5
Mulsch, A.6
Nussbaum, R.L.7
Muller, K.8
Drose, S.9
Brandt, U.10
Deller, T.11
Wirth, B.12
Kudin, A.P.13
Kunz, W.S.14
Auburger, G.15
-
74
-
-
67649383293
-
Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin
-
Hristova VA, Beasley SA, Rylett RJ, Shaw GS (2009) Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin. J Biol Chem 284: 14978-14986.
-
(2009)
J Biol Chem
, vol.284
, pp. 14978-14986
-
-
Hristova, V.A.1
Beasley, S.A.2
Rylett, R.J.3
Shaw, G.S.4
-
75
-
-
0031702640
-
Clinical and neuropathological aspects of autosomal recessive juvenile parkinsonism
-
Ishikawa A, Takahashi H (1998) Clinical and neuropathological aspects of autosomal recessive juvenile parkinsonism. J Neurol 245: P4-9.
-
(1998)
J Neurol
, vol.245
-
-
Ishikawa, A.1
Takahashi, H.2
-
76
-
-
10744221310
-
Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
-
Itier JM, Ibanez P, Mena MA, Abbas N, Cohen-Salmon C, Bohme GA, Laville M, Pratt J, Corti O, Pradier L, Ret G, Joubert C, Periquet M, Araujo F, Negroni J, Casarejos MJ, Canals S, Solano R, Serrano A, Gallego E, Sanchez M, Denefle P, Benavides J, Tremp G, Rooney TA, Brice A, Garcia de Yebenes J (2003) Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum Mol Genet 12: 2277-2291.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2277-2291
-
-
Itier, J.M.1
Ibanez, P.2
Mena, M.A.3
Abbas, N.4
Cohen-Salmon, C.5
Bohme, G.A.6
Laville, M.7
Pratt, J.8
Corti, O.9
Pradier, L.10
Ret, G.11
Joubert, C.12
Periquet, M.13
Araujo, F.14
Negroni, J.15
Casarejos, M.J.16
Canals, S.17
Solano, R.18
Serrano, A.19
Gallego, E.20
Sanchez, M.21
Denefle, P.22
Benavides, J.23
Tremp, G.24
Rooney, T.A.25
Brice, A.26
de Garcia, Y.J.27
more..
-
77
-
-
15544374722
-
Quantitative proteomic analysis of mitochondrial proteins: Relevance to Lewy body formation and Parkinson's disease
-
Jin J, Meredith GE, Chen L, Zhou Y, Xu J, Shie FS, Lockhart P, Zhang J (2005) Quantitative proteomic analysis of mitochondrial proteins: relevance to Lewy body formation and Parkinson's disease. Brain Res Mol Brain Res 134: 119-138.
-
(2005)
Brain Res Mol Brain Res
, vol.134
, pp. 119-138
-
-
Jin, J.1
Meredith, G.E.2
Chen, L.3
Zhou, Y.4
Xu, J.5
Shie, F.S.6
Lockhart, P.7
Zhang, J.8
-
78
-
-
33746296891
-
Proteomic identification of a stress protein, mortalin/ mthsp70/GRP75: Relevance to Parkinson disease
-
Jin J, Hulette C, Wang Y, Zhang T, Pan C, Wadhwa R, Zhang J (2006) Proteomic identification of a stress protein, mortalin/ mthsp70/GRP75: relevance to Parkinson disease. Mol Cell Proteomics 5: 1193-1204.
-
(2006)
Mol Cell Proteomics
, vol.5
, pp. 1193-1204
-
-
Jin, J.1
Hulette, C.2
Wang, Y.3
Zhang, T.4
Pan, C.5
Wadhwa, R.6
Zhang, J.7
-
79
-
-
34547780601
-
Parkinmediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels
-
Joch M, Ase AR, Chen CX, MacDonald PA, Kontogiannea M, Corera AT, Brice A, Seguela P, Fon EA (2007) Parkinmediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels. Mol Biol Cell 18: 3105-3118.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 3105-3118
-
-
Joch, M.1
Ase, A.R.2
Chen, C.X.3
Macdonald, P.A.4
Kontogiannea, M.5
Corera, A.T.6
Brice, A.7
Seguela, P.8
Fon, E.A.9
-
80
-
-
77958450202
-
Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1
-
Kamp F, Exner N, Lutz AK, Wender N, Hegermann J, Brunner B, Nuscher B, Bartels T, Giese A, Beyer K, Eimer S, Winklhofer KF, Haass C (2010) Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1. EMBO J 29: 3571-3589.
-
(2010)
EMBO J
, vol.29
, pp. 3571-3589
-
-
Kamp, F.1
Exner, N.2
Lutz, A.K.3
Wender, N.4
Hegermann, J.5
Brunner, B.6
Nuscher, B.7
Bartels, T.8
Giese, A.9
Beyer, K.10
Eimer, S.11
Winklhofer, K.F.12
Haass, C.13
-
81
-
-
68949129378
-
DNA damage induces nuclear translocation of parkin
-
Kao SY (2009) DNA damage induces nuclear translocation of parkin. J Biomed Sci 16: 67.
-
(2009)
J Biomed Sci
, vol.16
, pp. 67
-
-
Kao, S.Y.1
-
82
-
-
34347398050
-
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
-
Karbowski M, Neutzner A, Youle RJ (2007) The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. J Cell Biol 178: 71-84.
-
(2007)
J Cell Biol
, vol.178
, pp. 71-84
-
-
Karbowski, M.1
Neutzner, A.2
Youle, R.J.3
-
83
-
-
0242677753
-
A function for the mitochondrial chaperonin Hsp60 in the structure and transmission of mitochondrial DNA nucleoids in Saccharomyces cerevisiae
-
Kaufman BA, Kolesar JE, Perlman PS, Butow RA (2003) A function for the mitochondrial chaperonin Hsp60 in the structure and transmission of mitochondrial DNA nucleoids in Saccharomyces cerevisiae. J Cell Biol 163: 457-461.
-
(2003)
J Cell Biol
, vol.163
, pp. 457-461
-
-
Kaufman, B.A.1
Kolesar, J.E.2
Perlman, P.S.3
Butow, R.A.4
-
84
-
-
0037447901
-
Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts
-
Kaul SC, Yaguchi T, Taira K, Reddel RR, Wadhwa R (2003) Overexpressed mortalin (mot-2)/mthsp70/GRP75 and hTERT cooperate to extend the in vitro lifespan of human fibroblasts. Exp Cell Res 286: 96-101.
-
(2003)
Exp Cell Res
, vol.286
, pp. 96-101
-
-
Kaul, S.C.1
Yaguchi, T.2
Taira, K.3
Reddel, R.R.4
Wadhwa, R.5
-
85
-
-
0034759157
-
Loss of the mitochondrial Hsp70 functions causes aggregation of mitochondria in yeast cells
-
Kawai A, Nishikawa S, Hirata A, Endo T (2001) Loss of the mitochondrial Hsp70 functions causes aggregation of mitochondria in yeast cells. J Cell Sci 114: 3565-3574.
-
(2001)
J Cell Sci
, vol.114
, pp. 3565-3574
-
-
Kawai, A.1
Nishikawa, S.2
Hirata, A.3
Endo, T.4
-
86
-
-
68949206326
-
Mitochondrial Gene therapy augments mitochondrial physiology in a Parkinson's Disease cell model
-
Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett Jr JP (2009) Mitochondrial Gene therapy augments mitochondrial physiology in a Parkinson's Disease cell model. Hum Gene Ther 20: 897-907.
-
(2009)
Hum Gene Ther
, vol.20
, pp. 897-907
-
-
Keeney, P.M.1
Quigley, C.K.2
Dunham, L.D.3
Papageorge, C.M.4
Iyer, S.5
Thomas, R.R.6
Schwarz, K.M.7
Trimmer, P.A.8
Khan, S.M.9
Portell, F.R.10
Bergquist, K.E.11
Bennett, J.P.12
-
87
-
-
0036787533
-
Progression of nigrostriatal dysfunction in a parkin kindred: An [18F]dopa PET and clinical study
-
Khan NL, Brooks DJ, Pavese N, Sweeney MG, Wood NW, Lees AJ, Piccini P (2002) Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study. Brain 125: 2248-2256.
-
(2002)
Brain
, vol.125
, pp. 2248-2256
-
-
Khan, N.L.1
Brooks, D.J.2
Pavese, N.3
Sweeney, M.G.4
Wood, N.W.5
Lees, A.J.6
Piccini, P.7
-
88
-
-
20344400149
-
Parkin disease in a Brazilian kindred: Manifesting heterozygotes and clinical follow-up over 10 years
-
Khan NL, Horta W, Eunson L, Graham E, Johnson JO, Chang S, Davis M, Singleton A, Wood NW, Lees AJ (2005a) Parkin disease in a Brazilian kindred: Manifesting heterozygotes and clinical follow-up over 10 years. Mov Disord 20: 479-484.
-
(2005)
Mov Disord
, vol.20
, pp. 479-484
-
-
Khan, N.L.1
Horta, W.2
Eunson, L.3
Graham, E.4
Johnson, J.O.5
Chang, S.6
Davis, M.7
Singleton, A.8
Wood, N.W.9
Lees, A.J.10
-
89
-
-
11444265305
-
Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation
-
Khan NL, Scherfler C, Graham E, Bhatia KP, Quinn N, Lees AJ, Brooks DJ, Wood NW, Piccini P (2005b) Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single parkin mutation. Neurology 64: 134-136.
-
(2005)
Neurology
, vol.64
, pp. 134-136
-
-
Khan, N.L.1
Scherfler, C.2
Graham, E.3
Bhatia, K.P.4
Quinn, N.5
Lees, A.J.6
Brooks, D.J.7
Wood, N.W.8
Piccini, P.9
-
90
-
-
34247171756
-
Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans
-
Kimura K, Tanaka N, Nakamura N, Takano S, Ohkuma S (2007) Knockdown of mitochondrial heat shock protein 70 promotes progeria-like phenotypes in caenorhabditis elegans. J Biol Chem 282: 5910-5918.
-
(2007)
J Biol Chem
, vol.282
, pp. 5910-5918
-
-
Kimura, K.1
Tanaka, N.2
Nakamura, N.3
Takano, S.4
Ohkuma, S.5
-
91
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392: 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
92
-
-
34547489872
-
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice
-
Kitada T, Pisani A, Porter DR, Yamaguchi H, Tscherter A, Martella G, Bonsi P, Zhang C, Pothos EN, Shen J (2007) Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proc Natl Acad Sci U S A 104: 11441-11446.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11441-11446
-
-
Kitada, T.1
Pisani, A.2
Porter, D.R.3
Yamaguchi, H.4
Tscherter, A.5
Martella, G.6
Bonsi, P.7
Zhang, C.8
Pothos, E.N.9
Shen, J.10
-
93
-
-
70349923087
-
Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice
-
Kitada T, Tong Y, Gautier CA, Shen J (2009) Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice. J Neurochem 111: 696-702.
-
(2009)
J Neurochem
, vol.111
, pp. 696-702
-
-
Kitada, T.1
Tong, Y.2
Gautier, C.A.3
Shen, J.4
-
94
-
-
34250372427
-
Deciphering the role of heterozy gous mutations in genes associated with parkinsonism
-
Klein C, Lohmann-Hedrich K, Rogaeva E, Schlossmacher MG, Lang AE (2007) Deciphering the role of heterozy gous mutations in genes associated with parkinsonism. Lancet Neurol 6: 652-662.
-
(2007)
Lancet Neurol
, vol.6
, pp. 652-662
-
-
Klein, C.1
Lohmann-Hedrich, K.2
Rogaeva, E.3
Schlossmacher, M.G.4
Lang, A.E.5
-
95
-
-
60549117962
-
Parkinson disease(s): Is "Parkin disease" a distinct clinical entity?
-
Klein C, Lohmann K (2009) Parkinson disease(s): is "Parkin disease" a distinct clinical entity? Neurology 72: 106-107.
-
(2009)
Neurology
, vol.72
, pp. 106-107
-
-
Klein, C.1
Lohmann, K.2
-
96
-
-
0026520064
-
Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space
-
Koll H, Guiard B, Rassow J, Ostermann J, Horwich AL, Neupert W, Hartl FU (1992) Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space. Cell 68: 1163-1175.
-
(1992)
Cell
, vol.68
, pp. 1163-1175
-
-
Koll, H.1
Guiard, B.2
Rassow, J.3
Ostermann, J.4
Horwich, A.L.5
Neupert, W.6
Hartl, F.U.7
-
97
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Khrapko K (2006) Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet 38: 518-520.
-
(2006)
Nat Genet
, vol.38
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
98
-
-
0034943022
-
Parkin is associated with cellular vesicles
-
Kubo SI, Kitami T, Noda S, Shimura H, Uchiyama Y, Asakawa S, Minoshima S, Shimizu N, Mizuno Y, Hattori N (2001) Parkin is associated with cellular vesicles. J Neurochem 78: 42-54.
-
(2001)
J Neurochem
, vol.78
, pp. 42-54
-
-
Kubo, S.I.1
Kitami, T.2
Noda, S.3
Shimura, H.4
Uchiyama, Y.5
Asakawa, S.6
Minoshima, S.7
Shimizu, N.8
Mizuno, Y.9
Hattori, N.10
-
99
-
-
84859986458
-
Longlasting stress, quantitative changes in nitric oxide concentration and functional state of brain mitochondria
-
Kuchukashvili Z, Burjanadze G, Menabde K, Chachua M, Dachanidze N, Mikadze M, Koshoridze N (2012) Longlasting stress, quantitative changes in nitric oxide concentration and functional state of brain mitochondria. Acta Neurobiol Exp (Wars) 72: 40-50.
-
(2012)
Acta Neurobiol Exp (Wars)
, vol.72
, pp. 40-50
-
-
Kuchukashvili, Z.1
Burjanadze, G.2
Menabde, K.3
Chachua, M.4
Dachanidze, N.5
Mikadze, M.6
Koshoridze, N.7
-
100
-
-
33644778845
-
Parkin enhances mitochondrial biogenesis in proliferating cells
-
Kuroda Y, Mitsui T, Kunishige M, Shono M, Akaike M, Azuma H, Matsumoto T (2006) Parkin enhances mitochondrial biogenesis in proliferating cells. Hum Mol Genet 15: 883-895.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 883-895
-
-
Kuroda, Y.1
Mitsui, T.2
Kunishige, M.3
Shono, M.4
Akaike, M.5
Azuma, H.6
Matsumoto, T.7
-
101
-
-
0031930319
-
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice
-
Larsson NG, Wang J, Wilhelmsson H, Oldfors A, Rustin P, Lewandoski M, Barsh GS, Clayton DA (1998) Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice. Nat Genet 18: 231-236.
-
(1998)
Nat Genet
, vol.18
, pp. 231-236
-
-
Larsson, N.G.1
Wang, J.2
Wilhelmsson, H.3
Oldfors, A.4
Rustin, P.5
Lewandoski, M.6
Barsh, G.S.7
Clayton, D.A.8
-
102
-
-
30744443484
-
Dopamine covalently modifies and functionally inactivates parkin
-
LaVoie MJ, Ostaszewski BL, Weihofen A, Schlossmacher MG, Selkoe DJ (2005) Dopamine covalently modifies and functionally inactivates parkin. Nat Med 11: 1214-1221.
-
(2005)
Nat Med
, vol.11
, pp. 1214-1221
-
-
Lavoie, M.J.1
Ostaszewski, B.L.2
Weihofen, A.3
Schlossmacher, M.G.4
Selkoe, D.J.5
-
103
-
-
84873045973
-
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
-
Lazarou M, Narendra DP, Jin SM, Tekle E, Banerjee S, Youle RJ (2013) PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J Cell Biol 200: 163-172.
-
(2013)
J Cell Biol
, vol.200
, pp. 163-172
-
-
Lazarou, M.1
Narendra, D.P.2
Jin, S.M.3
Tekle, E.4
Banerjee, S.5
Youle, R.J.6
-
104
-
-
20044386298
-
Parkin mediates nonclassical, proteasomal- independent ubiquitination of synphilin-1: Implications for Lewy body formation
-
Lim KL, Chew KC, Tan JM, Wang C, Chung KK, Zhang Y, Tanaka Y, Smith W, Engelender S, Ross CA, Dawson VL, Dawson TM (2005) Parkin mediates nonclassical, proteasomal- independent ubiquitination of synphilin-1: implications for Lewy body formation. J Neurosci 25: 2002-2009.
-
(2005)
J Neurosci
, vol.25
, pp. 2002-2009
-
-
Lim, K.L.1
Chew, K.C.2
Tan, J.M.3
Wang, C.4
Chung, K.K.5
Zhang, Y.6
Tanaka, Y.7
Smith, W.8
Engelender, S.9
Ross, C.A.10
Dawson, V.L.11
Dawson, T.M.12
-
105
-
-
84859237566
-
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria
-
Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton W, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B (2012) Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria. PLoS Genet 8: e1002537.
-
(2012)
PLoS Genet
, vol.8
-
-
Liu, S.1
Sawada, T.2
Lee, S.3
Yu, W.4
Silverio, G.5
Alapatt, P.6
Millan, I.7
Shen, A.8
Saxton, W.9
Kanao, T.10
Takahashi, R.11
Hattori, N.12
Imai, Y.13
Lu, B.14
-
106
-
-
0042415580
-
How much phenotypic variation can be attributed to parkin genotype?
-
Lohmann E, Periquet M, Bonifati V, Wood NW, De Michele G, Bonnet AM, Fraix V, Broussolle E, Horstink MW, Vidailhet M, Verpillat P, Gasser T, Nicholl D, Teive H, Raskin S, Rascol O, Destee A, Ruberg M, Gasparini F, Meco G, Agid Y, Durr A, Brice A (2003) How much phenotypic variation can be attributed to parkin genotype? Ann Neurol 54: 176-185.
-
(2003)
Ann Neurol
, vol.54
, pp. 176-185
-
-
Lohmann, E.1
Periquet, M.2
Bonifati, V.3
Wood, N.W.4
de Michele, G.5
Bonnet, A.M.6
Fraix, V.7
Broussolle, E.8
Horstink, M.W.9
Vidailhet, M.10
Verpillat, P.11
Gasser, T.12
Nicholl, D.13
Teive, H.14
Raskin, S.15
Rascol, O.16
Destee, A.17
Ruberg, M.18
Gasparini, F.19
Meco, G.20
Agid, Y.21
Durr, A.22
Brice, A.23
more..
-
107
-
-
60849106352
-
Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein
-
Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW (2009) Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. J Neurosci 29: 1962-1976.
-
(2009)
J Neurosci
, vol.29
, pp. 1962-1976
-
-
Lu, X.H.1
Fleming, S.M.2
Meurers, B.3
Ackerson, L.C.4
Mortazavi, F.5
Lo, V.6
Hernandez, D.7
Sulzer, D.8
Jackson, G.R.9
Maidment, N.T.10
Chesselet, M.F.11
Yang, X.W.12
-
108
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene
-
Lucking CB, Durr A, Bonifati V, Vaughan J, De Michele G, Gasser T, Harhangi BS, Meco G, Denefle P, Wood NW, Agid Y, Brice A (2000) Association between early-onset Parkinson's disease and mutations in the parkin gene. N Engl J Med 342: 1560-1567.
-
(2000)
N Engl J Med
, vol.342
, pp. 1560-1567
-
-
Lucking, C.B.1
Durr, A.2
Bonifati, V.3
Vaughan, J.4
de Michele, G.5
Gasser, T.6
Harhangi, B.S.7
Meco, G.8
Denefle, P.9
Wood, N.W.10
Agid, Y.11
Brice, A.12
-
109
-
-
69249096578
-
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation
-
Lutz AK, Exner N, Fett ME, Schlehe JS, Kloos K, Lammermann K, Brunner B, Kurz-Drexler A, Vogel F, Reichert AS, Bouman L, Vogt-Weisenhorn D, Wurst W, Tatzelt J, Haass C, Winklhofer KF (2009) Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation. J Biol Chem 284: 22938-22951.
-
(2009)
J Biol Chem
, vol.284
, pp. 22938-22951
-
-
Lutz, A.K.1
Exner, N.2
Fett, M.E.3
Schlehe, J.S.4
Kloos, K.5
Lammermann, K.6
Brunner, B.7
Kurz-Drexler, A.8
Vogel, F.9
Reichert, A.S.10
Bouman, L.11
Vogt-Weisenhorn, D.12
Wurst, W.13
Tatzelt, J.14
Haass, C.15
Winklhofer, K.F.16
-
110
-
-
69449101151
-
Inhibition of mitochondrial fission favours mutant over wild-type mitochondrial DNA
-
Malena A, Loro E, Di Re M, Holt IJ, Vergani L (2009) Inhibition of mitochondrial fission favours mutant over wild-type mitochondrial DNA. Hum Mol Genet 18: 3407-3416.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3407-3416
-
-
Malena, A.1
Loro, E.2
Di Re, M.3
Holt, I.J.4
Vergani, L.5
-
113
-
-
33645635706
-
Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro
-
Matsuda N, Kitami T, Suzuki T, Mizuno Y, Hattori N, Tanaka K (2006) Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro. J Biol Chem 281: 3204-3209.
-
(2006)
J Biol Chem
, vol.281
, pp. 3204-3209
-
-
Matsuda, N.1
Kitami, T.2
Suzuki, T.3
Mizuno, Y.4
Hattori, N.5
Tanaka, K.6
-
114
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, Sou YS, Saiki S, Kawajiri S, Sato F, Kimura M, Komatsu M, Hattori N, Tanaka K (2010) PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J Cell Biol 189: 211-221.
-
(2010)
J Cell Biol
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
Sou, Y.S.7
Saiki, S.8
Kawajiri, S.9
Sato, F.10
Kimura, M.11
Komatsu, M.12
Hattori, N.13
Tanaka, K.14
-
115
-
-
1242292303
-
Region-specific analysis of mitochondrial DNA deletions in neurodegenerative disorders in humans
-
Mawrin C, Kirches E, Krause G, Schneider-Stock R, Bogerts B, Vorwerk CK, Dietzmann K (2004) Region-specific analysis of mitochondrial DNA deletions in neurodegenerative disorders in humans. Neurosci Lett 357: 111-114.
-
(2004)
Neurosci Lett
, vol.357
, pp. 111-114
-
-
Mawrin, C.1
Kirches, E.2
Krause, G.3
Schneider-Stock, R.4
Bogerts, B.5
Vorwerk, C.K.6
Dietzmann, K.7
-
116
-
-
79956007514
-
Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation
-
Meng F, Yao D, Shi Y, Kabakoff J, Wu W, Reicher J, Ma Y, Moosmann B, Masliah E, Lipton SA, Gu Z (2011) Oxidation of the cysteine-rich regions of parkin perturbs its E3 ligase activity and contributes to protein aggregation. Mol Neurodegener 6: 34.
-
(2011)
Mol Neurodegener
, vol.6
, pp. 34
-
-
Meng, F.1
Yao, D.2
Shi, Y.3
Kabakoff, J.4
Wu, W.5
Reicher, J.6
Ma, Y.7
Moosmann, B.8
Masliah, E.9
Lipton, S.A.10
Gu, Z.11
-
117
-
-
0037774459
-
LRP130, a pentatricopeptide motif protein with a noncanonical RNA-binding domain, is bound in vivo to mitochondrial and nuclear RNAs
-
Mili S, Pinol-Roma S (2003) LRP130, a pentatricopeptide motif protein with a noncanonical RNA-binding domain, is bound in vivo to mitochondrial and nuclear RNAs. Mol Cell Biol 23: 4972-4982.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4972-4982
-
-
Mili, S.1
Pinol-Roma, S.2
-
118
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
Mizushima N, Komatsu M (2011) Autophagy: renovation of cells and tissues. Cell 147: 728-741.
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
119
-
-
33846920571
-
p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain
-
Mogi M, Kondo T, Mizuno Y, Nagatsu T (2007) p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain. Neurosci Lett 414: 94-97.
-
(2007)
Neurosci Lett
, vol.414
, pp. 94-97
-
-
Mogi, M.1
Kondo, T.2
Mizuno, Y.3
Nagatsu, T.4
-
120
-
-
84861651595
-
A molecular signature in blood identifies early Parkinson's disease
-
Molochnikov L, Rabey JM, Dobronevsky E, Bonucelli U, Ceravolo R, Frosini D, Grunblatt E, Riederer P, Jacob C, Aharon-Peretz J, Bashenko Y, Youdim MB, Mandel SA (2012) A molecular signature in blood identifies early Parkinson's disease. Mol Neurodegener 7: 26.
-
(2012)
Mol Neurodegener
, vol.7
, pp. 26
-
-
Molochnikov, L.1
Rabey, J.M.2
Dobronevsky, E.3
Bonucelli, U.4
Ceravolo, R.5
Frosini, D.6
Grunblatt, E.7
Riederer, P.8
Jacob, C.9
Aharon-Peretz, J.10
Bashenko, Y.11
Youdim, M.B.12
Mandel, S.A.13
-
121
-
-
43549116100
-
Parkin mediates the degradation-independent ubiquitination of Hsp70
-
Moore DJ, West AB, Dikeman DA, Dawson VL, Dawson TM (2008) Parkin mediates the degradation-independent ubiquitination of Hsp70. J Neurochem 105: 1806-1819.
-
(2008)
J Neurochem
, vol.105
, pp. 1806-1819
-
-
Moore, D.J.1
West, A.B.2
Dikeman, D.A.3
Dawson, V.L.4
Dawson, T.M.5
-
122
-
-
77953666757
-
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
-
Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D, Van Coster R, Wurst W, Scorrano L, De Strooper B (2009) Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function. EMBO Mol Med 1: 99-111.
-
(2009)
EMBO Mol Med
, vol.1
, pp. 99-111
-
-
Morais, V.A.1
Verstreken, P.2
Roethig, A.3
Smet, J.4
Snellinx, A.5
Vanbrabant, M.6
Haddad, D.7
Frezza, C.8
Mandemakers, W.9
Vogt-Weisenhorn, D.10
van Coster, R.11
Wurst, W.12
Scorrano, L.13
de Strooper, B.14
-
123
-
-
0031721141
-
Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q
-
Mori H, Kondo T, Yokochi M, Matsumine H, Nakagawa- Hattori Y, Miyake T, Suda K, Mizuno Y (1998) Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q. Neurology 51: 890-892.
-
(1998)
Neurology
, vol.51
, pp. 890-892
-
-
Mori, H.1
Kondo, T.2
Yokochi, M.3
Matsumine, H.4
Nakagawa-Hattori, Y.5
Miyake, T.6
Suda, K.7
Mizuno, Y.8
-
124
-
-
57749100375
-
Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts
-
Mortiboys H, Thomas KJ, Koopman WJ, Klaffke S, Abou- Sleiman P, Olpin S, Wood NW, Willems PH, Smeitink JA, Cookson MR, Bandmann O (2008) Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts. Ann Neurol 64: 555-565.
-
(2008)
Ann Neurol
, vol.64
, pp. 555-565
-
-
Mortiboys, H.1
Thomas, K.J.2
Koopman, W.J.3
Klaffke, S.4
Abou-Sleiman, P.5
Olpin, S.6
Wood, N.W.7
Willems, P.H.8
Smeitink, J.A.9
Cookson, M.R.10
Bandmann, O.11
-
125
-
-
4544326057
-
Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations
-
Muftuoglu M, Elibol B, Dalmizrak O, Ercan A, Kulaksiz G, Ogus H, Dalkara T, Ozer N (2004) Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations. Mov Disord 19: 544-548.
-
(2004)
Mov Disord
, vol.19
, pp. 544-548
-
-
Muftuoglu, M.1
Elibol, B.2
Dalmizrak, O.3
Ercan, A.4
Kulaksiz, G.5
Ogus, H.6
Dalkara, T.7
Ozer, N.8
-
126
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen DF, Youle RJ (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 183: 795-803.
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
127
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, Cookson MR, Youle RJ (2010) PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol 8: e1000298.
-
(2010)
PLoS Biol
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
128
-
-
33644614514
-
TFAM-dependent and independent dynamics of mtDNA levels in C2C12 myoblasts caused by redox stress
-
Noack H, Bednarek T, Heidler J, Ladig R, Holtz J, Szibor M (2006) TFAM-dependent and independent dynamics of mtDNA levels in C2C12 myoblasts caused by redox stress. Biochim Biophys Acta 1760: 141-150.
-
(2006)
Biochim Biophys Acta
, vol.1760
, pp. 141-150
-
-
Noack, H.1
Bednarek, T.2
Heidler, J.3
Ladig, R.4
Holtz, J.5
Szibor, M.6
-
129
-
-
79958245892
-
Mitochondrial defect and PGC-1alpha dysfunction in parkin-associated familial Parkinson's disease
-
Pacelli C, De Rasmo D, Signorile A, Grattagliano I, di Tullio G, D'Orazio A, Nico B, Comi GP, Ronchi D, Ferranini E, Pirolo D, Seibel P, Schubert S, Gaballo A, Villani G, Cocco T (2011) Mitochondrial defect and PGC-1alpha dysfunction in parkin-associated familial Parkinson's disease. Biochim Biophys Acta 1812: 1041-1053.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1041-1053
-
-
Pacelli, C.1
de Rasmo, D.2
Signorile, A.3
Grattagliano, I.4
di Tullio, G.5
D'Orazio, A.6
Nico, B.7
Comi, G.P.8
Ronchi, D.9
Ferranini, E.10
Pirolo, D.11
Seibel, P.12
Schubert, S.13
Gaballo, A.14
Villani, G.15
Cocco, T.16
-
130
-
-
2442481789
-
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
-
Palacino JJ, Sagi D, Goldberg MS, Krauss S, Motz C, Wacker M, Klose J, Shen J (2004) Mitochondrial dysfunction and oxidative damage in parkin-deficient mice. J Biol Chem 279: 18614-18622.
-
(2004)
J Biol Chem
, vol.279
, pp. 18614-18622
-
-
Palacino, J.J.1
Sagi, D.2
Goldberg, M.S.3
Krauss, S.4
Motz, C.5
Wacker, M.6
Klose, J.7
Shen, J.8
-
131
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, Bae E, Kim J, Shong M, Kim JM, Chung J (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441: 1157-1161.
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.M.10
Chung, J.11
-
132
-
-
57749194390
-
The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process
-
Park J, Lee G, Chung J (2009) The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process. Biochem Biophys Res Commun 378: 518-523.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 518-523
-
-
Park, J.1
Lee, G.2
Chung, J.3
-
133
-
-
72849133538
-
Nigrostriatal dysfunction in homozygous and heterozygous parkin gene carriers: An 18F-dopa PET progression study
-
Pavese N, Khan NL, Scherfler C, Cohen L, Brooks DJ, Wood NW, Bhatia KP, Quinn NP, Lees AJ, Piccini P (2009) Nigrostriatal dysfunction in homozygous and heterozygous parkin gene carriers: an 18F-dopa PET progression study. Mov Disord 24: 2260-2266.
-
(2009)
Mov Disord
, vol.24
, pp. 2260-2266
-
-
Pavese, N.1
Khan, N.L.2
Scherfler, C.3
Cohen, L.4
Brooks, D.J.5
Wood, N.W.6
Bhatia, K.P.7
Quinn, N.P.8
Lees, A.J.9
Piccini, P.10
-
134
-
-
13844313915
-
Parkin-deficient mice are not a robust model of parkinsonism
-
Perez FA, Palmiter RD (2005) Parkin-deficient mice are not a robust model of parkinsonism. Proc Natl Acad Sci U S A 102: 2174-2179.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2174-2179
-
-
Perez, F.A.1
Palmiter, R.D.2
-
136
-
-
84857031377
-
Parkin, PINK1 and mitochondrial integrity: Emerging concepts of mitochondrial dysfunction in Parkinson's disease
-
Pilsl A, Winklhofer KF (2012) Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease. Acta Neuropathol 123: 173-188.
-
(2012)
Acta Neuropathol
, vol.123
, pp. 173-188
-
-
Pilsl, A.1
Winklhofer, K.F.2
-
137
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole AC, Thomas RE, Andrews LA, McBride HM, Whitworth AJ, Pallanck LJ (2008) The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci U S A 105: 1638-1643.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
138
-
-
77955844260
-
The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway
-
Poole AC, Thomas RE, Yu S, Vincow ES, Pallanck L (2010) The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway. PLoS One 5: e10054.
-
(2010)
PLoS One
, vol.5
-
-
Poole, A.C.1
Thomas, R.E.2
Yu, S.3
Vincow, E.S.4
Pallanck, L.5
-
139
-
-
84862689309
-
The neuropathology of genetic Parkinson's disease
-
Poulopoulos M, Levy OA, Alcalay RN (2012) The neuropathology of genetic Parkinson's disease. Mov Disord 27: 831-842.
-
(2012)
Mov Disord
, vol.27
, pp. 831-842
-
-
Poulopoulos, M.1
Levy, O.A.2
Alcalay, R.N.3
-
140
-
-
24644462201
-
Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers
-
Pramstaller PP, Schlossmacher MG, Jacques TS, Scaravilli F, Eskelson C, Pepivani I, Hedrich K, Adel S, Gonzales- McNeal M, Hilker R, Kramer PL, Klein C (2005) Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers. Ann Neurol 58: 411-422.
-
(2005)
Ann Neurol
, vol.58
, pp. 411-422
-
-
Pramstaller, P.P.1
Schlossmacher, M.G.2
Jacques, T.S.3
Scaravilli, F.4
Eskelson, C.5
Pepivani, I.6
Hedrich, K.7
Adel, S.8
Gonzales-McNeal, M.9
Hilker, R.10
Kramer, P.L.11
Klein, C.12
-
141
-
-
38049010435
-
Nuclear receptors and other nuclear transcription factors in mitochondria: Regulatory molecules in a new environment
-
Psarra AM, Sekeris CE (2008) Nuclear receptors and other nuclear transcription factors in mitochondria: regulatory molecules in a new environment. Biochim Biophys Acta 1783: 1-11.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 1-11
-
-
Psarra, A.M.1
Sekeris, C.E.2
-
142
-
-
77955029885
-
Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients
-
Rakovic A, Grunewald A, Seibler P, Ramirez A, Kock N, Orolicki S, Lohmann K, Klein C (2010) Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients. Hum Mol Genet 19: 3124-3137.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3124-3137
-
-
Rakovic, A.1
Grunewald, A.2
Seibler, P.3
Ramirez, A.4
Kock, N.5
Orolicki, S.6
Lohmann, K.7
Klein, C.8
-
143
-
-
79952369437
-
Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts
-
Rakovic A, Grunewald A, Kottwitz J, Bruggemann N, Pramstaller PP, Lohmann K, Klein C (2011a) Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts. PLoS One 6: e16746.
-
(2011)
PLoS One
, vol.6
-
-
Rakovic, A.1
Grunewald, A.2
Kottwitz, J.3
Bruggemann, N.4
Pramstaller, P.P.5
Lohmann, K.6
Klein, C.7
-
144
-
-
79955063199
-
PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1
-
Rakovic A, Grunewald A, Voges L, Hofmann S, Orolicki S, Lohmann K, Klein C (2011b) PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1. Parkinsons Dis 2011: 153979.
-
(2011)
Parkinsons Dis
, vol.2011
, pp. 153979
-
-
Rakovic, A.1
Grunewald, A.2
Voges, L.3
Hofmann, S.4
Orolicki, S.5
Lohmann, K.6
Klein, C.7
-
145
-
-
84873843566
-
Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: Study in human primary fibroblasts and induced pluripotent stem cell-derived neurons
-
Rakovic A, Shurkewitsch K, Seibler P, Grunewald A, Zanon A, Hagenah J, Krainc D, Klein C (2013) Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons. J Biol Chem 288: 2223-2237.
-
(2013)
J Biol Chem
, vol.288
, pp. 2223-2237
-
-
Rakovic, A.1
Shurkewitsch, K.2
Seibler, P.3
Grunewald, A.4
Zanon, A.5
Hagenah, J.6
Krainc, D.7
Klein, C.8
-
146
-
-
83755224757
-
Cellular strategies for making monoubiquitin signals
-
Ramanathan HN, Ye Y (2012) Cellular strategies for making monoubiquitin signals. Crit Rev Biochem Mol Biol 47: 17-28.
-
(2012)
Crit Rev Biochem Mol Biol
, vol.47
, pp. 17-28
-
-
Ramanathan, H.N.1
Ye, Y.2
-
147
-
-
79955073027
-
Parkin, A Top Level Manager in the Cell's Sanitation Department
-
Rankin CA, Roy A, Zhang Y, Richter M (2011) Parkin, A Top Level Manager in the Cell's Sanitation Department. Open Biochem J 5: 9-26.
-
(2011)
Open Biochem J
, vol.5
, pp. 9-26
-
-
Rankin, C.A.1
Roy, A.2
Zhang, Y.3
Richter, M.4
-
148
-
-
68249144254
-
A multitracer dopaminergic PET study of young-onset parkinsonian patients with and without parkin gene mutations
-
Ribeiro MJ, Thobois S, Lohmann E, du Montcel ST, Lesage S, Pelissolo A, Dubois B, Mallet L, Pollak P, Agid Y, Broussolle E, Brice A, Remy P (2009) A multitracer dopaminergic PET study of young-onset parkinsonian patients with and without parkin gene mutations. J Nucl Med 50: 1244-1250.
-
(2009)
J Nucl Med
, vol.50
, pp. 1244-1250
-
-
Ribeiro, M.J.1
Thobois, S.2
Lohmann, E.3
du Montcel, S.T.4
Lesage, S.5
Pelissolo, A.6
Dubois, B.7
Mallet, L.8
Pollak, P.9
Agid, Y.10
Broussolle, E.11
Brice, A.12
Remy, P.13
-
149
-
-
34548649412
-
Mortality, oxidative stress and tau accumulation during ageing in parkin null mice
-
Rodriguez-Navarro JA, Casarejos MJ, Menendez J, Solano RM, Rodal I, Gomez A, Yebenes JG, Mena MA (2007) Mortality, oxidative stress and tau accumulation during ageing in parkin null mice. J Neurochem 103: 98-114.
-
(2007)
J Neurochem
, vol.103
, pp. 98-114
-
-
Rodriguez-Navarro, J.A.1
Casarejos, M.J.2
Menendez, J.3
Solano, R.M.4
Rodal, I.5
Gomez, A.6
Yebenes, J.G.7
Mena, M.A.8
-
150
-
-
70349569938
-
Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair
-
Rothfuss O, Fischer H, Hasegawa T, Maisel M, Leitner P, Miesel F, Sharma M, Bornemann A, Berg D, Gasser T, Patenge N (2009) Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair. Hum Mol Genet 18: 3832-3850.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 3832-3850
-
-
Rothfuss, O.1
Fischer, H.2
Hasegawa, T.3
Maisel, M.4
Leitner, P.5
Miesel, F.6
Sharma, M.7
Bornemann, A.8
Berg, D.9
Gasser, T.10
Patenge, N.11
-
151
-
-
84866359459
-
Lewy body pathology and typical Parkinson disease in a patient with a heterozygous (R275W) mutation in the Parkin gene (PARK2)
-
Ruffmann C, Zini M, Goldwurm S, Bramerio M, Spinello S, Rusconi D, Gambacorta M, Tagliavini F, Pezzoli G, Giaccone G (2012) Lewy body pathology and typical Parkinson disease in a patient with a heterozygous (R275W) mutation in the Parkin gene (PARK2). Acta Neuropathol 123: 901-903.
-
(2012)
Acta Neuropathol
, vol.123
, pp. 901-903
-
-
Ruffmann, C.1
Zini, M.2
Goldwurm, S.3
Bramerio, M.4
Spinello, S.5
Rusconi, D.6
Gambacorta, M.7
Tagliavini, F.8
Pezzoli, G.9
Giaccone, G.10
-
152
-
-
79951812916
-
Telomere dysfunction induces metabolic and mitochondrial compromise
-
Sahin E, Colla S, Liesa M, Moslehi J, Muller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, Protopopov A, Ivanova E, Mahoney JE, Kost-Alimova M, Perry SR, Bronson R, Liao R, Mulligan R, Shirihai OS, Chin L, DePinho RA (2011) Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 470: 359-365.
-
(2011)
Nature
, vol.470
, pp. 359-365
-
-
Sahin, E.1
Colla, S.2
Liesa, M.3
Moslehi, J.4
Muller, F.L.5
Guo, M.6
Cooper, M.7
Kotton, D.8
Fabian, A.J.9
Walkey, C.10
Maser, R.S.11
Tonon, G.12
Foerster, F.13
Xiong, R.14
Wang, Y.A.15
Shukla, S.A.16
Jaskelioff, M.17
Martin, E.S.18
Heffernan, T.P.19
Protopopov, A.20
Ivanova, E.21
Mahoney, J.E.22
Kost-Alimova, M.23
Perry, S.R.24
Bronson, R.25
Liao, R.26
Mulligan, R.27
Shirihai, O.S.28
Chin, L.29
Depinho, R.A.30
more..
-
153
-
-
67549092006
-
Mutational screening of the mitochondrial transcription factors B1 and B2 (TFB1M and TFB2M) in Parkinson's disease
-
Sánchez-Ferrero E, Coto E, Blázquez M, Ribacoba R, Guisasola LM, Salvador C, Alvarez V. (2009) Mutational screening of the mitochondrial transcription factors B1 and B2 (TFB1M and TFB2M) in Parkinson's disease. Parkinsonism Relat Disord. 15: 468-470.
-
(2009)
Parkinsonism Relat Disord
, vol.15
, pp. 468-470
-
-
Sánchez-Ferrero, E.1
Coto, E.2
Blázquez, M.3
Ribacoba, R.4
Guisasola, L.M.5
Salvador, C.6
Alvarez, V.7
-
154
-
-
33846804056
-
A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine
-
Sang TK, Chang HY, Lawless GM, Ratnaparkhi A, Mee L, Ackerson LC, Maidment NT, Krantz DE, Jackson GR (2007) A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci 27: 981-992.
-
(2007)
J Neurosci
, vol.27
, pp. 981-992
-
-
Sang, T.K.1
Chang, H.Y.2
Lawless, G.M.3
Ratnaparkhi, A.4
Mee, L.5
Ackerson, L.C.6
Maidment, N.T.7
Krantz, D.E.8
Jackson, G.R.9
-
155
-
-
4143125488
-
Parkin-positive autosomal recessive juvenile Parkinsonism with alpha-synuclein- positive inclusions
-
Sasaki S, Shirata A, Yamane K, Iwata M (2004) Parkin-positive autosomal recessive juvenile Parkinsonism with alpha-synuclein- positive inclusions. Neurology 63: 678-682.
-
(2004)
Neurology
, vol.63
, pp. 678-682
-
-
Sasaki, S.1
Shirata, A.2
Yamane, K.3
Iwata, M.4
-
156
-
-
57649148823
-
Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1- related coactivator
-
Scarpulla RC (2008a) Nuclear control of respiratory chain expression by nuclear respiratory factors and PGC-1- related coactivator. Ann N Y Acad Sci 1147: 321-334.
-
(2008)
Ann N Y Acad Sci
, vol.1147
, pp. 321-334
-
-
Scarpulla, R.C.1
-
157
-
-
42049114034
-
Transcriptional paradigms in mammalian mitochondrial biogenesis and function
-
Scarpulla RC (2008b) Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol Rev 88: 611-638.
-
(2008)
Physiol Rev
, vol.88
, pp. 611-638
-
-
Scarpulla, R.C.1
-
158
-
-
79957960940
-
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
-
Scarpulla RC (2011) Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network. Biochim Biophys Acta 1813: 1269-1278.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1269-1278
-
-
Scarpulla, R.C.1
-
159
-
-
79955786943
-
Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells
-
Seibler P, Graziotto J, Jeong H, Simunovic F, Klein C, Krainc D (2011) Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cells. J Neurosci 31: 5970-5976.
-
(2011)
J Neurosci
, vol.31
, pp. 5970-5976
-
-
Seibler, P.1
Graziotto, J.2
Jeong, H.3
Simunovic, F.4
Klein, C.5
Krainc, D.6
-
160
-
-
84855973029
-
Analysis of PARK2 gene exon rearrangements in Russian patients with sporadic Parkinson's disease
-
Semenova EV, Shadrina MI, Slominsky PA, Ivanova- Smolenskaya IA, Bagyeva G, Illarioshkin SN, Limborska SA (2012) Analysis of PARK2 gene exon rearrangements in Russian patients with sporadic Parkinson's disease. Mov Disord 27: 139-142.
-
(2012)
Mov Disord
, vol.27
, pp. 139-142
-
-
Semenova, E.V.1
Shadrina, M.I.2
Slominsky, P.A.3
Ivanova-Smolenskaya, I.A.4
Bagyeva, G.5
Illarioshkin, S.N.6
Limborska, S.A.7
-
161
-
-
42949173485
-
Mortalin: A protein associated with progression of Parkinson disease?
-
Shi M, Jin J, Wang Y, Beyer RP, Kitsou E, Albin RL, Gearing M, Pan C, Zhang J (2008) Mortalin: a protein associated with progression of Parkinson disease? J Neuropathol Exp Neurol 67: 117-124.
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, pp. 117-124
-
-
Shi, M.1
Jin, J.2
Wang, Y.3
Beyer, R.P.4
Kitsou, E.5
Albin, R.L.6
Gearing, M.7
Pan, C.8
Zhang, J.9
-
162
-
-
0032957883
-
Immunohistochemical and subcellular localization of Parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients
-
Shimura H, Hattori N, Kubo S, Yoshikawa M, Kitada T, Matsumine H, Asakawa S, Minoshima S, Yamamura Y, Shimizu N, Mizuno Y (1999) Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients. Ann Neurol 45: 668-672.
-
(1999)
Ann Neurol
, vol.45
, pp. 668-672
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Yoshikawa, M.4
Kitada, T.5
Matsumine, H.6
Asakawa, S.7
Minoshima, S.8
Yamamura, Y.9
Shimizu, N.10
Mizuno, Y.11
-
163
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura H, Hattori N, Kubo S, Mizuno Y, Asakawa S, Minoshima S, Shimizu N, Iwai K, Chiba T, Tanaka K, Suzuki T (2000) Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet 25: 302-305.
-
(2000)
Nat Genet
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
164
-
-
79952303794
-
PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease
-
Shin JH, Ko HS, Kang H, Lee Y, Lee YI, Pletinkova O, Troconso JC, Dawson VL, Dawson TM (2011) PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease. Cell 144: 689-702.
-
(2011)
Cell
, vol.144
, pp. 689-702
-
-
Shin, J.H.1
Ko, H.S.2
Kang, H.3
Lee, Y.4
Lee, Y.I.5
Pletinkova, O.6
Troconso, J.C.7
Dawson, V.L.8
Dawson, T.M.9
-
165
-
-
77953529585
-
A compendium of human mitochondrial gene expression machinery with links to disease
-
Shutt TE, Shadel GS (2010) A compendium of human mitochondrial gene expression machinery with links to disease. Environ Mol Mutagen 51: 360-379.
-
(2010)
Environ Mol Mutagen
, vol.51
, pp. 360-379
-
-
Shutt, T.E.1
Shadel, G.S.2
-
166
-
-
0034938364
-
Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria
-
Spelbrink JN, Li FY, Tiranti V, Nikali K, Yuan QP, Tariq M, Wanrooij S, Garrido N, Comi G, Morandi L, Santoro L, Toscano A, Fabrizi GM, Somer H, Croxen R, Beeson D, Poulton J, Suomalainen A, Jacobs HT, Zeviani M, Larsson C (2001) Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria. Nat Genet 28: 223-231.
-
(2001)
Nat Genet
, vol.28
, pp. 223-231
-
-
Spelbrink, J.N.1
Li, F.Y.2
Tiranti, V.3
Nikali, K.4
Yuan, Q.P.5
Tariq, M.6
Wanrooij, S.7
Garrido, N.8
Comi, G.9
Morandi, L.10
Santoro, L.11
Toscano, A.12
Fabrizi, G.M.13
Somer, H.14
Croxen, R.15
Beeson, D.16
Poulton, J.17
Suomalainen, A.18
Jacobs, H.T.19
Zeviani, M.20
Larsson, C.21
more..
-
167
-
-
24144470504
-
Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin
-
Sriram SR, Li X, Ko HS, Chung KK, Wong E, Lim KL, Dawson VL, Dawson TM (2005) Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin. Hum Mol Genet 14: 2571-2586.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2571-2586
-
-
Sriram, S.R.1
Li, X.2
Ko, H.S.3
Chung, K.K.4
Wong, E.5
Lim, K.L.6
Dawson, V.L.7
Dawson, T.M.8
-
168
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jager S, Handschin C, Zheng K, Lin J, Yang W, Simon DK, Bachoo R, Spiegelman BM (2006) Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127: 397-408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
-
169
-
-
79961239061
-
Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo
-
Sterky FH, Lee S, Wibom R, Olson L, Larsson NG (2011) Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo. Proc Natl Acad Sci U S A 108: 12937-12942.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 12937-12942
-
-
Sterky, F.H.1
Lee, S.2
Wibom, R.3
Olson, L.4
Larsson, N.G.5
-
170
-
-
0034515773
-
Parkin expression in the adult mouse brain
-
Stichel CC, Augustin M, Kuhn K, Zhu XR, Engels P, Ullmer C, Lubbert H (2000) Parkin expression in the adult mouse brain. Eur J Neurosci 12: 4181-4194.
-
(2000)
Eur J Neurosci
, vol.12
, pp. 4181-4194
-
-
Stichel, C.C.1
Augustin, M.2
Kuhn, K.3
Zhu, X.R.4
Engels, P.5
Ullmer, C.6
Lubbert, H.7
-
171
-
-
0037137704
-
Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein
-
Stowers RS, Megeath LJ, Gorska-Andrzejak J, Meinertzhagen IA, Schwarz TL (2002) Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Neuron 36: 1063-1077.
-
(2002)
Neuron
, vol.36
, pp. 1063-1077
-
-
Stowers, R.S.1
Megeath, L.J.2
Gorska-Andrzejak, J.3
Meinertzhagen, I.A.4
Schwarz, T.L.5
-
172
-
-
77955398958
-
Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells
-
Suen DF, Narendra DP, Tanaka A, Manfredi G, Youle RJ (2010) Parkin overexpression selects against a deleterious mtDNA mutation in heteroplasmic cybrid cells. Proc Natl Acad Sci U S A 107: 11835-11840.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11835-11840
-
-
Suen, D.F.1
Narendra, D.P.2
Tanaka, A.3
Manfredi, G.4
Youle, R.J.5
-
173
-
-
0142039781
-
Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1
-
Suliman HB, Carraway MS, Welty-Wolf KE, Whorton AR, Piantadosi CA (2003) Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. J Biol Chem 278: 41510-41518.
-
(2003)
J Biol Chem
, vol.278
, pp. 41510-41518
-
-
Suliman, H.B.1
Carraway, M.S.2
Welty-Wolf, K.E.3
Whorton, A.R.4
Piantadosi, C.A.5
-
174
-
-
5444246214
-
Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis
-
Suliman HB, Welty-Wolf KE, Carraway M, Tatro L, Piantadosi CA (2004) Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis. Cardiovasc Res 64: 279-288.
-
(2004)
Cardiovasc Res
, vol.64
, pp. 279-288
-
-
Suliman, H.B.1
Welty-Wolf, K.E.2
Carraway, M.3
Tatro, L.4
Piantadosi, C.A.5
-
175
-
-
33745091901
-
Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: The GenePD study
-
Sun M, Latourelle JC, Wooten GF, Lew MF, Klein C, Shill HA, Golbe LI, Mark MH, Racette BA, Perlmutter JS, Parsian A, Guttman M, Nicholson G, Xu G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gillis T, MacDonald ME, Myers RH, Gusella JF (2006) Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study. Arch Neurol 63: 826-832.
-
(2006)
Arch Neurol
, vol.63
, pp. 826-832
-
-
Sun, M.1
Latourelle, J.C.2
Wooten, G.F.3
Lew, M.F.4
Klein, C.5
Shill, H.A.6
Golbe, L.I.7
Mark, M.H.8
Racette, B.A.9
Perlmutter, J.S.10
Parsian, A.11
Guttman, M.12
Nicholson, G.13
Xu, G.14
Wilk, J.B.15
Saint-Hilaire, M.H.16
Destefano, A.L.17
Prakash, R.18
Williamson, S.19
Suchowersky, O.20
Labelle, N.21
Growdon, J.H.22
Singer, C.23
Watts, R.L.24
Goldwurm, S.25
Pezzoli, G.26
Baker, K.B.27
Pramstaller, P.P.28
Burn, D.J.29
Chinnery, P.F.30
Sherman, S.31
Vieregge, P.32
Litvan, I.33
Gillis, T.34
Macdonald, M.E.35
Myers, R.H.36
Gusella, J.F.37
more..
-
176
-
-
0032476121
-
Differential expression of the parkin gene in the human brain and peripheral leukocytes
-
Sunada Y, Saito F, Matsumura K, Shimizu T (1998) Differential expression of the parkin gene in the human brain and peripheral leukocytes. Neurosci Lett 254: 180-182.
-
(1998)
Neurosci Lett
, vol.254
, pp. 180-182
-
-
Sunada, Y.1
Saito, F.2
Matsumura, K.3
Shimizu, T.4
-
177
-
-
80052320919
-
ParkDB: A Parkinson's disease gene expression database
-
Oxford
-
Taccioli C, Tegner J, Maselli V, Gomez-Cabrero D, Altobelli G, Emmett W, Lescai F, Gustincich S, Stupka E (2011) ParkDB: a Parkinson's disease gene expression database. Database (Oxford) 2011: bar007.
-
(2011)
Database
-
-
Taccioli, C.1
Tegner, J.2
Maselli, V.3
Gomez-Cabrero, D.4
Altobelli, G.5
Emmett, W.6
Lescai, F.7
Gustincich, S.8
Stupka, E.9
-
178
-
-
28344442591
-
Differential expression of splice variant and wild-type parkin in sporadic Parkinson's disease
-
Tan EK, Shen H, Tan JM, Lim KL, Fook-Chong S, Hu WP, Paterson MC, Chandran VR, Yew K, Tan C, Yuen Y, Pavanni R, Wong MC, Puvan K, Zhao Y (2005) Differential expression of splice variant and wild-type parkin in sporadic Parkinson's disease. Neurogenetics 6: 179-184.
-
(2005)
Neurogenetics
, vol.6
, pp. 179-184
-
-
Tan, E.K.1
Shen, H.2
Tan, J.M.3
Lim, K.L.4
Fook-Chong, S.5
Hu, W.P.6
Paterson, M.C.7
Chandran, V.R.8
Yew, K.9
Tan, C.10
Yuen, Y.11
Pavanni, R.12
Wong, M.C.13
Puvan, K.14
Zhao, Y.15
-
179
-
-
77950499364
-
Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network
-
Tanaka A (2010) Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network. FEBS Lett 584: 1386-1392.
-
(2010)
FEBS Lett
, vol.584
, pp. 1386-1392
-
-
Tanaka, A.1
-
180
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ (2010) Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin. J Cell Biol 191: 1367-1380.
-
(2010)
J Cell Biol
, vol.191
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
181
-
-
84879699457
-
-
The Parkinson Disease Mutation Database, accessed May 29th, 2013
-
The Parkinson Disease Mutation Database. http://www.molgen.ua.ac.be/PDmutDB; accessed May 29th, 2013
-
-
-
-
182
-
-
79956323688
-
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
-
Thomas KJ, McCoy MK, Blackinton J, Beilina A, van der Brug M, Sandebring A, Miller D, Maric D, Cedazo- Minguez A, Cookson MR (2011) DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy. Hum Mol Genet 20: 40-50.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 40-50
-
-
Thomas, K.J.1
McCoy, M.K.2
Blackinton, J.3
Beilina, A.4
van der Brug, M.5
Sandebring, A.6
Miller, D.7
Maric, D.8
Cedazo-Minguez, A.9
Cookson, M.R.10
-
183
-
-
80051767315
-
Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factorkappa B
-
Tran TA, Nguyen AD, Chang J, Goldberg MS, Lee JK, Tansey MG (2011) Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factorkappa B. PLoS One 6: e23660.
-
(2011)
PLoS One
, vol.6
-
-
Tran, T.A.1
Nguyen, A.D.2
Chang, J.3
Goldberg, M.S.4
Lee, J.K.5
Tansey, M.G.6
-
184
-
-
35348941129
-
CHIP chaperones wild type p53 tumor suppressor protein
-
Tripathi V, Ali A, Bhat R, Pati U (2007) CHIP chaperones wild type p53 tumor suppressor protein. J Biol Chem 282: 28441-28454.
-
(2007)
J Biol Chem
, vol.282
, pp. 28441-28454
-
-
Tripathi, V.1
Ali, A.2
Bhat, R.3
Pati, U.4
-
185
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, Ali Z, Del Turco D, Bentivoglio AR, Healy DG, Albanese A, Nussbaum R, Gonzalez-Maldonado R, Deller T, Salvi S, Cortelli P, Gilks WP, Latchman DS, Harvey RJ, Dallapiccola B, Auburger G, Wood NW (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304: 1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
186
-
-
0035957112
-
Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations
-
van de Warrenburg BP, Lammens M, Lucking CB, Denefle P, Wesseling P, Booij J, Praamstra P, Quinn N, Brice A, Horstink MW (2001) Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations. Neurology 56: 555-557.
-
(2001)
Neurology
, vol.56
, pp. 555-557
-
-
van de Warrenburg, B.P.1
Lammens, M.2
Lucking, C.B.3
Denefle, P.4
Wesseling, P.5
Booij, J.6
Praamstra, P.7
Quinn, N.8
Brice, A.9
Horstink, M.W.10
-
187
-
-
84875910694
-
Sulfhydration mediates neuroprotective actions of parkin
-
Vandiver MS, Paul BD, Xu R, Karuppagounder S, Rao F, Snowman AM, Ko HS, Lee YI, Dawson VL, Dawson TM, Sen N, Snyder SH (2013) Sulfhydration mediates neuroprotective actions of parkin. Nat Commun 4: 1626.
-
(2013)
Nat Commun
, vol.4
, pp. 1626
-
-
Vandiver, M.S.1
Paul, B.D.2
Xu, R.3
Karuppagounder, S.4
Rao, F.5
Snowman, A.M.6
Ko, H.S.7
Lee, Y.I.8
Dawson, V.L.9
Dawson, T.M.10
Sen, N.11
Snyder, S.H.12
-
188
-
-
77953618132
-
Imaging movement-related activity in medicated Parkinassociated and sporadic Parkinson's disease
-
van Eimeren T, Binkofski F, Buhmann C, Hagenah J, Strafella AP, Pramstaller PP, Siebner HR, Klein C (2010) Imaging movement-related activity in medicated Parkinassociated and sporadic Parkinson's disease. Parkinsonism Relat Disord 16: 384-387.
-
(2010)
Parkinsonism Relat Disord
, vol.16
, pp. 384-387
-
-
van Eimeren, T.1
Binkofski, F.2
Buhmann, C.3
Hagenah, J.4
Strafella, A.P.5
Pramstaller, P.P.6
Siebner, H.R.7
Klein, C.8
-
189
-
-
67649760168
-
Mitochondrial dynamics in Parkinson's disease
-
Van Laar VS, Berman SB (2009) Mitochondrial dynamics in Parkinson's disease. Exp Neurol 218: 247-256.
-
(2009)
Exp Neurol
, vol.218
, pp. 247-256
-
-
van Laar, V.S.1
Berman, S.B.2
-
190
-
-
79551603345
-
Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization
-
Van Laar VS, Arnold B, Cassady SJ, Chu CT, Burton EA, Berman SB (2011) Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization. Hum Mol Genet 20: 927-940.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 927-940
-
-
van Laar, V.S.1
Arnold, B.2
Cassady, S.J.3
Chu, C.T.4
Burton, E.A.5
Berman, S.B.6
-
191
-
-
72849153163
-
Mapping preclinical compensation in Parkinson's disease: An imaging genomics approach
-
van Nuenen BF, van Eimeren T, van der Vegt JP, Buhmann C, Klein C, Bloem BR, Siebner HR (2009) Mapping preclinical compensation in Parkinson's disease: an imaging genomics approach. Mov Disord 24 Suppl 2: S703-710.
-
(2009)
Mov Disord
, vol.24
, Issue.SUPPL. 2
-
-
van Nuenen, B.F.1
van Eimeren, T.2
van der Vegt, J.P.3
Buhmann, C.4
Klein, C.5
Bloem, B.R.6
Siebner, H.R.7
-
192
-
-
10444251205
-
Imaging of dopaminergic dysfunction with [123I] FP-CIT SPECT in early-onset parkin disease
-
Varrone A, Pellecchia MT, Amboni M, Sansone V, Salvatore E, Ghezzi D, Garavaglia B, Brice A, Brunetti A, Bonavita V, De Michele G, Salvatore M, Pappata S, Barone P (2004) Imaging of dopaminergic dysfunction with [123I] FP-CIT SPECT in early-onset parkin disease. Neurology 63: 2097-2103.
-
(2004)
Neurology
, vol.63
, pp. 2097-2103
-
-
Varrone, A.1
Pellecchia, M.T.2
Amboni, M.3
Sansone, V.4
Salvatore, E.5
Ghezzi, D.6
Garavaglia, B.7
Brice, A.8
Brunetti, A.9
Bonavita, V.10
de Michele, G.11
Salvatore, M.12
Pappata, S.13
Barone, P.14
-
193
-
-
30044434872
-
Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans
-
Ved R, Saha S, Westlund B, Perier C, Burnam L, Sluder A, Hoener M, Rodrigues CM, Alfonso A, Steer C, Liu L, Przedborski S, Wolozin B (2005) Similar patterns of mitochondrial vulnerability and rescue induced by genetic modification of alpha-synuclein, parkin, and DJ-1 in Caenorhabditis elegans. J Biol Chem 280: 42655-42668.
-
(2005)
J Biol Chem
, vol.280
, pp. 42655-42668
-
-
Ved, R.1
Saha, S.2
Westlund, B.3
Perier, C.4
Burnam, L.5
Sluder, A.6
Hoener, M.7
Rodrigues, C.M.8
Alfonso, A.9
Steer, C.10
Liu, L.11
Przedborski, S.12
Wolozin, B.13
-
194
-
-
23044506102
-
Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions
-
Verstreken P, Ly CV, Venken KJ, Koh TW, Zhou Y, Bellen HJ (2005) Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron 47: 365-378.
-
(2005)
Neuron
, vol.47
, pp. 365-378
-
-
Verstreken, P.1
Ly, C.V.2
Venken, K.J.3
Koh, T.W.4
Zhou, Y.5
Bellen, H.J.6
-
195
-
-
76549094100
-
Genetic screening reveals high frequency of PARK2 mutations and reduced Parkin expression conferring risk for Parkinsonism in North West India
-
Vinish M, Prabhakar S, Khullar M, Verma I, Anand A (2010) Genetic screening reveals high frequency of PARK2 mutations and reduced Parkin expression conferring risk for Parkinsonism in North West India. J Neurol Neurosurg Psychiatry 81: 166-170.
-
(2010)
J Neurol Neurosurg Psychiatry
, vol.81
, pp. 166-170
-
-
Vinish, M.1
Prabhakar, S.2
Khullar, M.3
Verma, I.4
Anand, A.5
-
196
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrane J, Moore DJ, Dawson VL, Grailhe R, Dawson TM, Li C, Tieu K, Przedborski S (2010) PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc Natl Acad Sci U S A 107: 378-383.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
de Vries, R.L.5
Kim, J.6
May, J.7
Tocilescu, M.A.8
Liu, W.9
Ko, H.S.10
Magrane, J.11
Moore, D.J.12
Dawson, V.L.13
Grailhe, R.14
Dawson, T.M.15
Li, C.16
Tieu, K.17
Przedborski, S.18
-
197
-
-
3242677684
-
Loss of locus coeruleus neurons and reduced startle in parkin null mice
-
Von Coelln R, Thomas B, Savitt JM, Lim KL, Sasaki M, Hess EJ, Dawson VL, Dawson TM (2004) Loss of locus coeruleus neurons and reduced startle in parkin null mice. Proc Natl Acad Sci U S A 101: 10744-10749.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10744-10749
-
-
von Coelln, R.1
Thomas, B.2
Savitt, J.M.3
Lim, K.L.4
Sasaki, M.5
Hess, E.J.6
Dawson, V.L.7
Dawson, T.M.8
-
198
-
-
29644448325
-
Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function
-
Wang C, Ko HS, Thomas B, Tsang F, Chew KC, Tay SP, Ho MW, Lim TM, Soong TW, Pletnikova O, Troncoso J, Dawson VL, Dawson TM, Lim KL (2005) Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function. Hum Mol Genet 14: 3885-3897.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3885-3897
-
-
Wang, C.1
Ko, H.S.2
Thomas, B.3
Tsang, F.4
Chew, K.C.5
Tay, S.P.6
Ho, M.W.7
Lim, T.M.8
Soong, T.W.9
Pletnikova, O.10
Troncoso, J.11
Dawson, V.L.12
Dawson, T.M.13
Lim, K.L.14
-
199
-
-
4644278845
-
Brain parenchyma sonography detects preclinical parkinsonism
-
Walter U, Klein C, Hilker R, Benecke R, Pramstaller PP, Dressler D (2004) Brain parenchyma sonography detects preclinical parkinsonism. Mov Disord 19: 1445-1449.
-
(2004)
Mov Disord
, vol.19
, pp. 1445-1449
-
-
Walter, U.1
Klein, C.2
Hilker, R.3
Benecke, R.4
Pramstaller, P.P.5
Dressler, D.6
-
200
-
-
79953231682
-
Parkin ubiquitinates Drp1 for proteasome-dependent degradation: Implication of dysregulated mitochondrial dynamics in Parkinson disease
-
Wang H, Song P, Du L, Tian W, Yue W, Liu M, Li D, Wang B, Zhu Y, Cao C, Zhou J, Chen Q (2011) Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease. J Biol Chem 286: 11649-11658.
-
(2011)
J Biol Chem
, vol.286
, pp. 11649-11658
-
-
Wang, H.1
Song, P.2
Du, L.3
Tian, W.4
Yue, W.5
Liu, M.6
Li, D.7
Wang, B.8
Zhu, Y.9
Cao, C.10
Zhou, J.11
Chen, Q.12
-
201
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
-
Wang X, Winter D, Ashrafi G, Schlehe J, Wong YL, Selkoe D, Rice S, Steen J, LaVoie MJ, Schwarz TL (2011) PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 147: 893-906.
-
(2011)
Cell
, vol.147
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
Ashrafi, G.3
Schlehe, J.4
Wong, Y.L.5
Selkoe, D.6
Rice, S.7
Steen, J.8
Lavoie, M.J.9
Schwarz, T.L.10
-
202
-
-
33748746678
-
Human mitochondrial DNA nucleoids are linked to protein folding machinery and metabolic enzymes at the mitochondrial inner membrane
-
Wang Y, Bogenhagen DF (2006) Human mitochondrial DNA nucleoids are linked to protein folding machinery and metabolic enzymes at the mitochondrial inner membrane. J Biol Chem 281: 25791-25802.
-
(2006)
J Biol Chem
, vol.281
, pp. 25791-25802
-
-
Wang, Y.1
Bogenhagen, D.F.2
-
203
-
-
36349020165
-
MDM2 chaperones the p53 tumor suppressor
-
Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M (2007) MDM2 chaperones the p53 tumor suppressor. J Biol Chem 282: 32603-32612.
-
(2007)
J Biol Chem
, vol.282
, pp. 32603-32612
-
-
Wawrzynow, B.1
Zylicz, A.2
Wallace, M.3
Hupp, T.4
Zylicz, M.5
-
204
-
-
64549112144
-
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking
-
Weihofen A, Thomas KJ, Ostaszewski BL, Cookson MR, Selkoe DJ (2009) Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry 48: 2045-2052.
-
(2009)
Biochemistry
, vol.48
, pp. 2045-2052
-
-
Weihofen, A.1
Thomas, K.J.2
Ostaszewski, B.L.3
Cookson, M.R.4
Selkoe, D.J.5
-
205
-
-
34249713698
-
Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations
-
Wong ES, Tan JM, Wang C, Zhang Z, Tay SP, Zaiden N, Ko HS, Dawson VL, Dawson TM, Lim KL (2007) Relative sensitivity of parkin and other cysteine-containing enzymes to stress-induced solubility alterations. J Biol Chem 282: 12310-12318.
-
(2007)
J Biol Chem
, vol.282
, pp. 12310-12318
-
-
Wong, E.S.1
Tan, J.M.2
Wang, C.3
Zhang, Z.4
Tay, S.P.5
Zaiden, N.6
Ko, H.S.7
Dawson, V.L.8
Dawson, T.M.9
Lim, K.L.10
-
206
-
-
49349087497
-
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
-
Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, Downward J, Mansfield L, Jat P, Taylor J, Heales S, Duchen MR, Latchman D, Tabrizi SJ, Wood NW (2008) PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PLoS One 3: e2455.
-
(2008)
PLoS One
, vol.3
-
-
Wood-Kaczmar, A.1
Gandhi, S.2
Yao, Z.3
Abramov, A.Y.4
Miljan, E.A.5
Keen, G.6
Stanyer, L.7
Hargreaves, I.8
Klupsch, K.9
Deas, E.10
Downward, J.11
Mansfield, L.12
Jat, P.13
Taylor, J.14
Heales, S.15
Duchen, M.R.16
Latchman, D.17
Tabrizi, S.J.18
Wood, N.W.19
-
207
-
-
20444451210
-
Parkin stabilizes microtubules through strong binding mediated by three independent domains
-
Yang F, Jiang Q, Zhao J, Ren Y, Sutton MD, Feng J (2005) Parkin stabilizes microtubules through strong binding mediated by three independent domains. J Biol Chem 280: 17154-17162.
-
(2005)
J Biol Chem
, vol.280
, pp. 17154-17162
-
-
Yang, F.1
Jiang, Q.2
Zhao, J.3
Ren, Y.4
Sutton, M.D.5
Feng, J.6
-
208
-
-
79959374989
-
Mitochondrial dysfunction induced by knockdown of mortalin is rescued by Parkin
-
Yang H, Zhou X, Liu X, Yang L, Chen Q, Zhao D, Zuo J, Liu W (2011) Mitochondrial dysfunction induced by knockdown of mortalin is rescued by Parkin. Biochem Biophys Res Commun 410: 114-120.
-
(2011)
Biochem Biophys Res Commun
, vol.410
, pp. 114-120
-
-
Yang, H.1
Zhou, X.2
Liu, X.3
Yang, L.4
Chen, Q.5
Zhao, D.6
Zuo, J.7
Liu, W.8
-
209
-
-
33746080412
-
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
-
Yang Y, Gehrke S, Imai Y, Huang Z, Ouyang Y, Wang JW, Yang L, Beal MF, Vogel H, Lu B (2006) Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci U S A 103: 10793-10798.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10793-10798
-
-
Yang, Y.1
Gehrke, S.2
Imai, Y.3
Huang, Z.4
Ouyang, Y.5
Wang, J.W.6
Yang, L.7
Beal, M.F.8
Vogel, H.9
Lu, B.10
-
210
-
-
44349195101
-
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
-
Yang Y, Ouyang Y, Yang L, Beal MF, McQuibban A, Vogel H, Lu B (2008) Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery. Proc Natl Acad Sci U S A 105: 7070-7075.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 7070-7075
-
-
Yang, Y.1
Ouyang, Y.2
Yang, L.3
Beal, M.F.4
McQuibban, A.5
Vogel, H.6
Lu, B.7
-
211
-
-
3242733689
-
Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity
-
Yao D, Gu Z, Nakamura T, Shi ZQ, Ma Y, Gaston B, Palmer LA, Rockenstein EM, Zhang Z, Masliah E, Uehara T, Lipton SA (2004) Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity. Proc Natl Acad Sci U S A 101: 10810-10814.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10810-10814
-
-
Yao, D.1
Gu, Z.2
Nakamura, T.3
Shi, Z.Q.4
Ma, Y.5
Gaston, B.6
Palmer, L.A.7
Rockenstein, E.M.8
Zhang, Z.9
Masliah, E.10
Uehara, T.11
Lipton, S.A.12
-
212
-
-
79960097010
-
Neuropharmacological approach against MPTP (1-methyl- 4-phenyl-1,2,3,6- tetrahydropyridine)-induced mouse model of Parkinson's disease
-
Yokoyama H, Kuroiwa H, Kasahara J, Araki T (2011) Neuropharmacological approach against MPTP (1-methyl- 4-phenyl-1,2,3,6- tetrahydropyridine)-induced mouse model of Parkinson's disease. Acta Neurobiol Exp (Wars) 71: 269-280.
-
(2011)
Acta Neurobiol Exp (Wars)
, vol.71
, pp. 269-280
-
-
Yokoyama, H.1
Kuroiwa, H.2
Kasahara, J.3
Araki, T.4
-
213
-
-
0037051942
-
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/ Grp75
-
Yokoyama K, Fukumoto K, Murakami T, Harada S, Hosono R, Wadhwa R, Mitsui Y, Ohkuma S (2002) Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/ Grp75. FEBS Lett 516: 53-57.
-
(2002)
FEBS Lett
, vol.516
, pp. 53-57
-
-
Yokoyama, K.1
Fukumoto, K.2
Murakami, T.3
Harada, S.4
Hosono, R.5
Wadhwa, R.6
Mitsui, Y.7
Ohkuma, S.8
-
214
-
-
18544365399
-
Human mitochondrial transcription factor A binds preferentially to oxidatively damaged DNA
-
Yoshida Y, Izumi H, Ise T, Uramoto H, Torigoe T, Ishiguchi H, Murakami T, Tanabe M, Nakayama Y, Itoh H, Kasai H, Kohno K (2002) Human mitochondrial transcription factor A binds preferentially to oxidatively damaged DNA. Biochem Biophys Res Commun 295: 945-951.
-
(2002)
Biochem Biophys Res Commun
, vol.295
, pp. 945-951
-
-
Yoshida, Y.1
Izumi, H.2
Ise, T.3
Uramoto, H.4
Torigoe, T.5
Ishiguchi, H.6
Murakami, T.7
Tanabe, M.8
Nakayama, Y.9
Itoh, H.10
Kasai, H.11
Kohno, K.12
-
215
-
-
0038418297
-
P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA
-
Yoshida Y, Izumi H, Torigoe T, Ishiguchi H, Itoh H, Kang D, Kohno K (2003) P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA. Cancer Res 63: 3729-3734.
-
(2003)
Cancer Res
, vol.63
, pp. 3729-3734
-
-
Yoshida, Y.1
Izumi, H.2
Torigoe, T.3
Ishiguchi, H.4
Itoh, H.5
Kang, D.6
Kohno, K.7
-
216
-
-
61949346360
-
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection
-
Yuan H, Perry CN, Huang C, Iwai-Kanai E, Carreira RS, Glembotski CC, Gottlieb RA (2009) LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am J Physiol Heart Circ Physiol 296: H470-479.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Yuan, H.1
Perry, C.N.2
Huang, C.3
Iwai-Kanai, E.4
Carreira, R.S.5
Glembotski, C.C.6
Gottlieb, R.A.7
-
217
-
-
80053635472
-
Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
-
Zhang C, Lin M, Wu R, Wang X, Yang B, Levine AJ, Hu W, Feng Z (2011) Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect. Proc Natl Acad Sci U S A 108: 16259-16264.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 16259-16264
-
-
Zhang, C.1
Lin, M.2
Wu, R.3
Wang, X.4
Yang, B.5
Levine, A.J.6
Hu, W.7
Feng, Z.8
-
218
-
-
23044502947
-
Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms
-
Zhang Y, James M, Middleton FA, Davis RL (2005) Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms. Am J Med Genet B Neuropsychiatr Genet 137B: 5-16.
-
(2005)
Am J Med Genet B Neuropsychiatr Genet
, vol.137 B
, pp. 5-16
-
-
Zhang, Y.1
James, M.2
Middleton, F.A.3
Davis, R.L.4
-
219
-
-
77958072667
-
PGC- 1alpha, a potential therapeutic target for early intervention in Parkinson's disease
-
Zheng B, Liao Z, Locascio JJ, Lesniak KA, Roderick SS, Watt ML, Eklund AC, Zhang-James Y, Kim PD, Hauser MA, Grunblatt E, Moran LB, Mandel SA, Riederer P, Miller RM, Federoff HJ, Wullner U, Papapetropoulos S, Youdim MB, Cantuti-Castelvetri I, Young AB, Vance JM, Davis RL, Hedreen JC, Adler CH, Beach TG, Graeber MB, Middleton FA, Rochet JC, Scherzer CR (2010) PGC- 1alpha, a potential therapeutic target for early intervention in Parkinson's disease. Sci Transl Med 2: 52ra73.
-
(2010)
Sci Transl Med
, vol.2
-
-
Zheng, B.1
Liao, Z.2
Locascio, J.J.3
Lesniak, K.A.4
Roderick, S.S.5
Watt, M.L.6
Eklund, A.C.7
Zhang-James, Y.8
Kim, P.D.9
Hauser, M.A.10
Grunblatt, E.11
Moran, L.B.12
Mandel, S.A.13
Riederer, P.14
Miller, R.M.15
Federoff, H.J.16
Wullner, U.17
Papapetropoulos, S.18
Youdim, M.B.19
Cantuti-Castelvetri, I.20
Young, A.B.21
Vance, J.M.22
Davis, R.L.23
Hedreen, J.C.24
Adler, C.H.25
Beach, T.G.26
Graeber, M.B.27
Middleton, F.A.28
Rochet, J.C.29
Scherzer, C.R.30
more..
-
220
-
-
33947228781
-
Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice
-
Zhou H, Falkenburger BH, Schulz JB, Tieu K, Xu Z, Xia XG (2007) Silencing of the Pink1 gene expression by conditional RNAi does not induce dopaminergic neuron death in mice. Int J Biol Sci 3: 242-250.
-
(2007)
Int J Biol Sci
, vol.3
, pp. 242-250
-
-
Zhou, H.1
Falkenburger, B.H.2
Schulz, J.B.3
Tieu, K.4
Xu, Z.5
Xia, X.G.6
-
221
-
-
77950384477
-
Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin
-
Ziviani E, Tao RN, Whitworth AJ (2010) Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin. Proc Natl Acad Sci U S A 107: 5018-5023.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 5018-5023
-
-
Ziviani, E.1
Tao, R.N.2
Whitworth, A.J.3
-
222
-
-
77955437274
-
How could Parkin-mediated ubiquitination of mitofusin promote mitophagy?
-
Ziviani E, Whitworth AJ (2010) How could Parkin-mediated ubiquitination of mitofusin promote mitophagy? Autophagy 6: 660-662.
-
(2010)
Autophagy
, vol.6
, pp. 660-662
-
-
Ziviani, E.1
Whitworth, A.J.2
|