PGC-1-related Coactivator (PRC), a sensor of metabolic stress, orchestrates a redox-sensitive program of inflammatory gene expression

Journal of Biological Chemistry

Volumn 286, Issue 46, 2011, Pages 39715-39725

  Gleyzer, Natalie ^a   Scarpulla, Richard C ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATP LEVEL; CELL STRESS; COACTIVATORS; COFACTORS; COMPLEX PHENOTYPE; DEGENERATIVE DISEASE; DOMINANT NEGATIVE; GLUCOSE DEPRIVATION; INFLAMMATORY GENES; INFLAMMATORY RESPONSE; METABOLIC STRESS; MICROENVIRONMENTS; MITOCHONDRIAL DYSFUNCTION; NUCLEAR GENES; NUCLEAR RESPIRATORY FACTORS; PROTEIN LEVEL; RESPIRATORY ENZYMES; RESPIRATORY FUNCTION; TRANSIENT EXPRESSION; UNCOUPLERS;

BIOELECTRIC POTENTIALS; CYANIDES; GLUCOSE; METABOLISM; MITOCHONDRIA;

GENE EXPRESSION;

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; GLUCOSE; LACTIC ACID; PGC 1 RELATED COACTIVATOR; PROTEIN; TRANSCRIPTION FACTOR NRF1; UNCLASSIFIED DRUG;

ADAPTATION; ARTICLE; CELL GROWTH; CELL STRESS; DEGENERATIVE DISEASE; GENE EXPRESSION; GENE IDENTIFICATION; GENE INDUCTION; INFLAMMATION; METABOLIC STRESS; MICROARRAY ANALYSIS; NEOPLASM; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ADENOSINE TRIPHOSPHATE; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INFLAMMATION; NUCLEAR RESPIRATORY FACTOR 1; OXIDATION-REDUCTION; PROTON IONOPHORES; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS;

EID: 81155123695     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.291575     Document Type: Article

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