Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

Journal of Biological Chemistry

Volumn 284, Issue 34, 2009, Pages 22938-22951

  Kathrin Lutz, A ^a   Exner, Nicole ^a   Fett, Mareike E ^a   Schleke, Julia S ^a   Kloos, Karina ^b   Lämmermann, Kerstin ^a   Brunner, Bettina ^a   Kurz Drexler, Annerose ^b   Vogel, Frank ^c   Reichert, Andreas S ^d   Bouman, Lena ^a   Vogt Weisenhorn, Daniela ^b   Wurst, Wolfgang ^b   Tatzelt, Jörg ^a   Haass, Christian ^a   Winklhofer, Konstanze F ^a,e  

^a UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d GOETHE UNIVERSITY   (Germany)

^e NONE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DOMINANT-NEGATIVE MUTANTS; DOWN-REGULATION; DROSOPHILA MELANOGASTER; HUMAN CELLS; MITOCHONDRIAL FRAGMENTATION; MITOCHONDRIAL FUSION; MITOCHONDRIAL MORPHOLOGY; PARKIN GENES;

MAMMALS; MORPHOLOGY;

CELL MEMBRANES;

ADENOSINE TRIPHOSPHATE; HYBRID PROTEIN; MITOCHONDRIAL PROTEIN; MITOFUSIN 2; PARKIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE INDUCED PUTATIVE KINASE 1; PROTEIN DRP1; PROTEIN OPA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DNA FRAGMENTATION; DOWN REGULATION; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENE LOSS; GENETIC ANALYSIS; HUMAN; HUMAN CELL; MITOCHONDRION; MORPHOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CELL LINE; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GTP-BINDING PROTEINS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; UBIQUITIN-PROTEIN LIGASES;

DROSOPHILA MELANOGASTER; MAMMALIA;

EID: 69249096578     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.035774     Document Type: Article

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