Mechanisms mediating spinal and bulbar muscular atrophy: Investigations into polyglutamine-expanded androgen receptor function and dysfunction

Frontiers in Neurology

Volumn 4 MAY, Issue , 2013, Pages

  Beitel, Lenore K ^a,b   Alvarado, Carlos ^a,b   Mokhtar, Shaza ^a,b   Paliouras, Miltiadis ^a,b   Trifiro, Mark ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Androgen receptor; Gain of function; Kennedy's disease; Loss of function; Mouse models; Neuromuscular disorder; Polyglutamine disease; Spinal and bulbar muscular atrophy

Indexed keywords

ANDROGEN RECEPTOR; HEAT SHOCK PROTEIN; POLYGLUTAMINE; PROTEASOME; RNA; SEROTONIN AGONIST; TRANSCRIPTION FACTOR; UBIQUITIN;

ACETYLATION; ANDROGEN INSENSITIVITY SYNDROME; ARTICLE; AUTOPHAGY; CELL NUCLEUS INCLUSION BODY; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME INHIBITION; HUMAN; INTRACELLULAR SIGNALING; KENNEDY DISEASE; MOLECULAR MECHANICS; MOTOR NEURON DISEASE; MUSCLE ATROPHY; NERVE DEGENERATION; NERVE FIBER TRANSPORT; NONHUMAN; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS INHIBITION; PROTEIN TRANSPORT; RNA SPLICING; UBIQUITINATION;

EID: 84878834369     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2013.00053     Document Type: Article

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