-
1
-
-
0034094873
-
Glutamine repeats and neurodegenera-tion
-
Zoghbi HY, Orr HT 2000 Glutamine repeats and neurodegenera-tion. Annu Rev Neurosci 23:217-247
-
(2000)
Annu Rev Neurosci
, vol.23
, pp. 217-247
-
-
Zoghbi, H.Y.1
Orr, H.T.2
-
2
-
-
0014310582
-
Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait
-
Kennedy WR, Alter M, Sung JH 1968 Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait. Neurology 18:671-680
-
(1968)
Neurology
, vol.18
, pp. 671-680
-
-
Kennedy, W.R.1
Alter, M.2
Sung, J.H.3
-
3
-
-
0025800526
-
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
-
La Spada AR, Wilson EM, Lubahn DB, Harding AE, Fischbeck KH 1991 Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature 352:77-79
-
(1991)
Nature
, vol.352
, pp. 77-79
-
-
la Spada, A.R.1
Wilson, E.M.2
Lubahn, D.B.3
Harding, A.E.4
Fischbeck, K.H.5
-
4
-
-
15144342225
-
Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy
-
Li M, Miwa S, Kobayashi Y, Merry DE, Yamamoto M, Tanaka F, Doyu M, Hashizume Y, Fischbeck KH, Sobue G 1998 Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy. Ann Neurol 44:249-254
-
(1998)
Ann Neurol
, vol.44
, pp. 249-254
-
-
Li, M.1
Miwa, S.2
Kobayashi, Y.3
Merry, D.E.4
Yamamoto, M.5
Tanaka, F.6
Doyu, M.7
Hashizume, Y.8
Fischbeck, K.H.9
Sobue, G.10
-
5
-
-
0034285017
-
CREB-binding protein sequestration by expanded polyglutamine
-
McCampbell A, Taylor JP, Taye AA, Robitschek J, Li M, Walcott J, Merry D, Chai Y, Paulson H, Sobue G, Fischbeck KH 2000 CREB-binding protein sequestration by expanded polyglutamine. Hum Mol Genet 9:2197-2202
-
(2000)
Hum Mol Genet
, vol.9
, pp. 2197-2202
-
-
McCampbell, A.1
Taylor, J.P.2
Taye, A.A.3
Robitschek, J.4
Li, M.5
Walcott, J.6
Merry, D.7
Chai, Y.8
Paulson, H.9
Sobue, G.10
Fischbeck, K.H.11
-
6
-
-
0031838352
-
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
-
Cummings CJ, Mancini MA, Antalffy B, DeFranco DB, Orr HT, Zoghbi HY 1998 Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat Genet 19:148-154
-
(1998)
Nat Genet
, vol.19
, pp. 148-154
-
-
Cummings, C.J.1
Mancini, M.A.2
Antalffy, B.3
Defranco, D.B.4
Orr, H.T.5
Zoghbi, H.Y.6
-
7
-
-
0032945938
-
Poly-glutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone
-
Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA 1999 Poly-glutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone. Hum Mol Genet 8:731-741
-
(1999)
Hum Mol Genet
, vol.8
, pp. 731-741
-
-
Stenoien, D.L.1
Cummings, C.J.2
Adams, H.P.3
Mancini, M.G.4
Patel, K.5
Demartino, G.N.6
Marcelli, M.7
Weigel, N.L.8
Mancini, M.A.9
-
8
-
-
0033071176
-
Protein fate in neurodegenerative proteinopa-thies: Polyglutamine diseases join the (mis)fold
-
Paulson HL 1999 Protein fate in neurodegenerative proteinopa-thies: polyglutamine diseases join the (mis)fold. Am J Hum Genet 64:339-345
-
(1999)
Am J Hum Genet
, vol.64
, pp. 339-345
-
-
Paulson, H.L.1
-
9
-
-
0032475941
-
Ataxin-1 nuclear localization and aggregation: Role in polyglutamine-induced disease in SCA1 transgenic mice
-
Klement IA, Skinner PJ, Kaytor MD, Yi H, Hersch SM, Clark HB, Zoghbi HY, Orr HT 1998 Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice. Cell 95:41-53
-
(1998)
Cell
, vol.95
, pp. 41-53
-
-
Klement, I.A.1
Skinner, P.J.2
Kaytor, M.D.3
Yi, H.4
Hersch, S.M.5
Clark, H.B.6
Zoghbi, H.Y.7
Orr, H.T.8
-
10
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
Arrasate M, Mitra S, Schweitzer ES, Segal MR, Finkbeiner S 2004 Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 431:805-810
-
(2004)
Nature
, vol.431
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
11
-
-
34047269594
-
Soluble androgen receptor oligomers underlie pathology in a mouse model of spinobulbar muscular atrophy
-
Li M, Chevalier-Larsen ES, Merry DE, Diamond MI 2007 Soluble androgen receptor oligomers underlie pathology in a mouse model of spinobulbar muscular atrophy. J Biol Chem 282:3157-3164
-
(2007)
J Biol Chem
, vol.282
, pp. 3157-3164
-
-
Li, M.1
Chevalier-Larsen, E.S.2
Merry, D.E.3
Diamond, M.I.4
-
12
-
-
38349158062
-
Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic
-
Takahashi T, Kikuchi S, Katada S, Nagai Y, Nishizawa M, On-odera O 2008 Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic. Hum Mol Genet 17:345-356
-
(2008)
Hum Mol Genet
, vol.17
, pp. 345-356
-
-
Takahashi, T.1
Kikuchi, S.2
Katada, S.3
Nagai, Y.4
Nishizawa, M.5
On-Odera, O.6
-
13
-
-
33744961169
-
Amyloid fibrils of mammalian prion protein are highly toxic to cultured cells and primary neurons
-
Novitskaya V, Bocharova OV, Bronstein I, Baskakov IV 2006 Amyloid fibrils of mammalian prion protein are highly toxic to cultured cells and primary neurons. J Biol Chem 281:13828-13836
-
(2006)
J Biol Chem
, vol.281
, pp. 13828-13836
-
-
Novitskaya, V.1
Bocharova, O.V.2
Bronstein, I.3
Baskakov, I.V.4
-
14
-
-
0034098057
-
Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract
-
Simeoni S, Mancini MA, Stenoien DL, Marcelli M, Weigel NL, Zanisi M, Martini L, Poletti A 2000 Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract. Hum Mol Genet 9:133-144
-
(2000)
Hum Mol Genet
, vol.9
, pp. 133-144
-
-
Simeoni, S.1
Mancini, M.A.2
Stenoien, D.L.3
Marcelli, M.4
Weigel, N.L.5
Zanisi, M.6
Martini, L.7
Poletti, A.8
-
15
-
-
33745592187
-
Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy
-
Thomas Jr PS, Fraley GS, Damian V, Damien V, Woodke LB, Zapata F, Sopher BL, Plymate SR, La Spada AR 2006 Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy. Hum Mol Genet 15:2225-2238
-
(2006)
Hum Mol Genet
, vol.15
, pp. 2225-2238
-
-
Thomas, P.S.1
Fraley, G.S.2
Damian, V.3
Damien, V.4
Woodke, L.B.5
Zapata, F.6
Sopher, B.L.7
Plymate, S.R.8
la Spada, A.R.9
-
16
-
-
0034977306
-
Multiple founder effects in spinal and bul-bar muscular atrophy (SBMA, Kennedy disease) around the world
-
Lund A, Udd B, Juvonen V, Andersen PM, Cederquist K, Davis M, Gellera C, Kölmel C, Ronnevi LO, Sperfeld AD, Sörensen SA, Tranebjaerg L, Van Maldergem L, Watanabe M, Weber M, Yeung L, Savontaus ML 2001 Multiple founder effects in spinal and bul-bar muscular atrophy (SBMA, Kennedy disease) around the world. Eur J Hum Genet 9:431-436
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 431-436
-
-
Lund, A.1
Udd, B.2
Juvonen, V.3
Andersen, P.M.4
Cederquist, K.5
Davis, M.6
Gellera, C.7
Kölmel, C.8
Ronnevi, L.O.9
Sperfeld, A.D.10
Sörensen, S.A.11
Tranebjaerg, L.12
van Maldergem, L.13
Watanabe, M.14
Weber, M.15
Yeung, L.16
Savontaus, M.L.17
-
17
-
-
77952320968
-
Lipid rafts: Keys to neurodegeneration
-
Schengrund CL 2010 Lipid rafts: keys to neurodegeneration. Brain Res Bull 82:7-17
-
(2010)
Brain Res Bull
, vol.82
, pp. 7-17
-
-
Schengrund, C.L.1
-
18
-
-
34547928773
-
A conserved mechanism for steroid receptor translocation to the plasma membrane
-
Pedram A, Razandi M, Sainson RC, Kim JK, Hughes CC, Levin ER 2007 A conserved mechanism for steroid receptor translocation to the plasma membrane. J Biol Chem 282:22278-22288
-
(2007)
J Biol Chem
, vol.282
, pp. 22278-22288
-
-
Pedram, A.1
Razandi, M.2
Sainson, R.C.3
Kim, J.K.4
Hughes, C.C.5
Levin, E.R.6
-
19
-
-
20044371007
-
Membrane androgen receptor activation induces apoptotic regression of human prostate cancer cells in vitro and in vivo
-
Hatzoglou A, Kampa M, Kogia C, Charalampopoulos I, Theodoro-poulos PA, Anezinis P, Dambaki C, Papakonstanti EA, Stathopou-los EN, Stournaras C, Gravanis A, Castanas E 2005 Membrane androgen receptor activation induces apoptotic regression of human prostate cancer cells in vitro and in vivo. J Clin Endocrinol Metab 90:893-903
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 893-903
-
-
Hatzoglou, A.1
Kampa, M.2
Kogia, C.3
Charalampopoulos, I.4
Theodoro-Poulos, P.A.5
Anezinis, P.6
Dambaki, C.7
Papakonstanti, E.A.8
Stathopou-Los, E.N.9
Stournaras, C.10
Gravanis, A.11
Castanas, E.12
-
20
-
-
33745081485
-
Activation of membrane androgen receptors potentiates the antiproliferative effects of paclitaxel on human prostate cancer cells
-
Kampa M, Kogia C, Theodoropoulos PA, Anezinis P, Charalampopoulos I, Papakonstanti EA, Stathopoulos EN, Hatzoglou A, Stournaras C, Gravanis A, Castanas E 2006 Activation of membrane androgen receptors potentiates the antiproliferative effects of paclitaxel on human prostate cancer cells. Mol Cancer Ther 5:1342-1351
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1342-1351
-
-
Kampa, M.1
Kogia, C.2
Theodoropoulos, P.A.3
Anezinis, P.4
Charalampopoulos, I.5
Papakonstanti, E.A.6
Stathopoulos, E.N.7
Hatzoglou, A.8
Stournaras, C.9
Gravanis, A.10
Castanas, E.11
-
21
-
-
0032830850
-
Testosterone signaling through internalizable surface receptors in androgen receptor-free macrophages
-
Benten WP, Lieberherr M, Stamm O, Wrehlke C, Guo Z, Wunder-lich F 1999 Testosterone signaling through internalizable surface receptors in androgen receptor-free macrophages. Mol Biol Cell 10:3113-3123
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3113-3123
-
-
Benten, W.P.1
Lieberherr, M.2
Stamm, O.3
Wrehlke, C.4
Guo, Z.5
Wunder-Lich, F.6
-
22
-
-
0008593290
-
Functional testosterone receptors in plasma membranes of T cells
-
Benten WP, Lieberherr M, Giese G, Wrehlke C, Stamm O, Sekeris CE, Mossmann H, Wunderlich F 1999 Functional testosterone receptors in plasma membranes of T cells. FASEB J 13:123-133
-
(1999)
FASEB J
, vol.13
, pp. 123-133
-
-
Benten, W.P.1
Lieberherr, M.2
Giese, G.3
Wrehlke, C.4
Stamm, O.5
Sekeris, C.E.6
Mossmann, H.7
Wunderlich, F.8
-
23
-
-
3342938066
-
Testosterone activates mitogen-activated protein kinase and the cAMP response element binding protein transcription factor in Sertoli cells
-
Fix C, Jordan C, Cano P, Walker WH 2004 Testosterone activates mitogen-activated protein kinase and the cAMP response element binding protein transcription factor in Sertoli cells. Proc Natl Acad Sci USA 101:10919-10924
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10919-10924
-
-
Fix, C.1
Jordan, C.2
Cano, P.3
Walker, W.H.4
-
24
-
-
33645519245
-
Dihydrotestosterone differentially modulates the mitogen-activated protein kinase and the phos-phoinositide 3-kinase/Akt pathways through the nuclear and novel membrane androgen receptor in C6 cells
-
Gatson JW, Kaur P, Singh M 2006 Dihydrotestosterone differentially modulates the mitogen-activated protein kinase and the phos-phoinositide 3-kinase/Akt pathways through the nuclear and novel membrane androgen receptor in C6 cells. Endocrinology 147: 2028-2034
-
(2006)
Endocrinology
, vol.147
, pp. 2028-2034
-
-
Gatson, J.W.1
Kaur, P.2
Singh, M.3
-
25
-
-
34249824292
-
Activation of a membrane-associated androgen receptor promotes cell death in primary cortical astrocytes
-
Gatson JW, Singh M 2007 Activation of a membrane-associated androgen receptor promotes cell death in primary cortical astrocytes. Endocrinology 148:2458-2464
-
(2007)
Endocrinology
, vol.148
, pp. 2458-2464
-
-
Gatson, J.W.1
Singh, M.2
-
26
-
-
34249816182
-
Testosterone activates mitogen-activated protein kinase via Src kinase and the epidermal growth factor receptor in Sertoli cells
-
Cheng J, Watkins SC, Walker WH 2007 Testosterone activates mitogen-activated protein kinase via Src kinase and the epidermal growth factor receptor in Sertoli cells. Endocrinology 148:2066-2074
-
(2007)
Endocrinology
, vol.148
, pp. 2066-2074
-
-
Cheng, J.1
Watkins, S.C.2
Walker, W.H.3
-
27
-
-
35748980862
-
Phos-phoinositide 3-kinase-independent non-genomic signals transit from the androgen receptor to Akt1 in membrane raft microdo-mains
-
Cinar B, Mukhopadhyay NK, Meng G, Freeman MR 2007 Phos-phoinositide 3-kinase-independent non-genomic signals transit from the androgen receptor to Akt1 in membrane raft microdo-mains. J Biol Chem 282:29584-29593
-
(2007)
J Biol Chem
, vol.282
, pp. 29584-29593
-
-
Cinar, B.1
Mukhopadhyay, N.K.2
Meng, G.3
Freeman, M.R.4
-
28
-
-
0028922314
-
Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: Possible pathogenetic relevance for the (CAG)n-expanded neuronopathies
-
Kazemi-Esfarjani P, Trifiro MA, Pinsky L 1995 Evidence for a repressive function of the long polyglutamine tract in the human androgen receptor: possible pathogenetic relevance for the (CAG)n-expanded neuronopathies. Hum Mol Genet 4:523-527
-
(1995)
Hum Mol Genet
, vol.4
, pp. 523-527
-
-
Kazemi-Esfarjani, P.1
Trifiro, M.A.2
Pinsky, L.3
-
29
-
-
0037101834
-
Altered transcriptional regulation in cells expressing the expanded polyglutamine androgen receptor
-
Lieberman AP, Harmison G, Strand AD, Olson JM, Fischbeck KH 2002 Altered transcriptional regulation in cells expressing the expanded polyglutamine androgen receptor. Hum Mol Genet 11: 1967-1976
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1967-1976
-
-
Lieberman, A.P.1
Harmison, G.2
Strand, A.D.3
Olson, J.M.4
Fischbeck, K.H.5
-
30
-
-
0026465350
-
Neuroblastoma X spinal cord (NSC) hybrid cell lines resemble developing motor neurons
-
Cashman NR, Durham HD, Blusztajn JK, Oda K, Tabira T, Shaw IT, Dahrouge S, Antel JP 1992 Neuroblastoma X spinal cord (NSC) hybrid cell lines resemble developing motor neurons. Dev Dyn 194: 209-221
-
(1992)
Dev Dyn
, vol.194
, pp. 209-221
-
-
Cashman, N.R.1
Durham, H.D.2
Blusztajn, J.K.3
Oda, K.4
Tabira, T.5
Shaw, I.T.6
Dahrouge, S.7
Antel, J.P.8
-
31
-
-
0030947287
-
The CAG repeat within the androgen receptor gene and its relationship to prostate cancer
-
Giovannucci E, Stampfer MJ, Krithivas K, Brown M, Dahl D, Bruf-sky A, Talcott J, Hennekens CH, Kantoff PW 1997 The CAG repeat within the androgen receptor gene and its relationship to prostate cancer. Proc Natl Acad Sci USA 94:3320-3323
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3320-3323
-
-
Giovannucci, E.1
Stampfer, M.J.2
Krithivas, K.3
Brown, M.4
Dahl, D.5
Bruf-Sky, A.6
Talcott, J.7
Hennekens, C.H.8
Kantoff, P.W.9
-
32
-
-
0036801362
-
Is the androgen receptor CAG repeat length significant for prostate cancer?
-
Giovannucci E 2002 Is the androgen receptor CAG repeat length significant for prostate cancer? Cancer Epidemiol Biomarkers Prev 11:985-986
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 985-986
-
-
Giovannucci, E.1
-
33
-
-
0035971563
-
AP-1 proteins in the adult brain: Facts and fiction about effectors of neuroprotection and neurodegenera-tion
-
Herdegen T, Waetzig V 2001 AP-1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegenera-tion. Oncogene 20:2424-2437
-
(2001)
Oncogene
, vol.20
, pp. 2424-2437
-
-
Herdegen, T.1
Waetzig, V.2
-
34
-
-
7244240786
-
Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neurons
-
Lindwall C, Dahlin L, Lundborg G, Kanje M 2004 Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neurons. Mol Cell Neurosci 27:267-279
-
(2004)
Mol Cell Neurosci
, vol.27
, pp. 267-279
-
-
Lindwall, C.1
Dahlin, L.2
Lundborg, G.3
Kanje, M.4
-
35
-
-
3242730442
-
The AP-1 transcription factor c-Jun is required for efficient axonal regeneration
-
Raivich G, Bohatschek M, Da Costa C, Iwata O, Galiano M, Hris-tova M, Nateri AS, Makwana M, Riera-Sans L, Wolfer DP, Lipp HP, Aguzzi A, Wagner EF, Behrens A 2004 The AP-1 transcription factor c-Jun is required for efficient axonal regeneration. Neuron 43:57-67
-
(2004)
Neuron
, vol.43
, pp. 57-67
-
-
Raivich, G.1
Bohatschek, M.2
da Costa, C.3
Iwata, O.4
Galiano, M.5
Hris-Tova, M.6
Nateri, A.S.7
Makwana, M.8
Riera-Sans, L.9
Wolfer, D.P.10
Lipp, H.P.11
Aguzzi, A.12
Wagner, E.F.13
Behrens, A.14
-
36
-
-
33847280410
-
Mild surfection of neural cells, especially mo-toneurons, in primary culture and cell lines
-
Rakotoarivelo C, Petite D, de Weille J, Lumbroso S, Privat A, Sultan C, Mersel M 2007 Mild surfection of neural cells, especially mo-toneurons, in primary culture and cell lines. Exp Neurol 204:118- 130
-
(2007)
Exp Neurol 204:118-
, pp. 130
-
-
Rakotoarivelo, C.1
Petite, D.2
de Weille, J.3
Lumbroso, S.4
Privat, A.5
Sultan, C.6
Mersel, M.7
-
37
-
-
22244469306
-
A simplified method for the preparation of detergent-free lipid rafts
-
Macdonald JL, Pike LJ 2005 A simplified method for the preparation of detergent-free lipid rafts. J Lipid Res 46:1061-1067
-
(2005)
J Lipid Res
, vol.46
, pp. 1061-1067
-
-
Macdonald, J.L.1
Pike, L.J.2
-
38
-
-
43049120228
-
Androgen regulation of axon growth and neurite extension in mo-toneurons
-
Fargo KN, Galbiati M, Foecking EM, Poletti A, Jones KJ 2008 Androgen regulation of axon growth and neurite extension in mo-toneurons. Horm Behav 53:716-728
-
(2008)
Horm Behav
, vol.53
, pp. 716-728
-
-
Fargo, K.N.1
Galbiati, M.2
Foecking, E.M.3
Poletti, A.4
Jones, K.J.5
-
39
-
-
0029044628
-
Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment
-
Mayor S, Maxfield FR 1995 Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Mol Biol Cell 6:929-944
-
(1995)
Mol Biol Cell
, vol.6
, pp. 929-944
-
-
Mayor, S.1
Maxfield, F.R.2
-
40
-
-
3142514201
-
Protein aggregation and neurodegen-erative disease
-
Ross CA, Poirier MA 2004 Protein aggregation and neurodegen-erative disease. Nat Med 10(Suppl):S10-S17
-
(2004)
Nat Med
, vol.10
, Issue.SUPPL.
-
-
Ross, C.A.1
Poirier, M.A.2
-
41
-
-
25844487226
-
Diseases of unstable repeat expansion: Mechanisms and common principles
-
Gatchel JR, Zoghbi HY 2005 Diseases of unstable repeat expansion: mechanisms and common principles. Nat Rev Genet 6:743-755
-
(2005)
Nat Rev Genet
, vol.6
, pp. 743-755
-
-
Gatchel, J.R.1
Zoghbi, H.Y.2
-
42
-
-
0031948607
-
Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy
-
Merry DE, Kobayashi Y, Bailey CK, Taye AA, Fischbeck KH 1998 Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy. Hum Mol Genet 7:693-701
-
(1998)
Hum Mol Genet
, vol.7
, pp. 693-701
-
-
Merry, D.E.1
Kobayashi, Y.2
Bailey, C.K.3
Taye, A.A.4
Fischbeck, K.H.5
-
43
-
-
0034708793
-
Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract
-
Kobayashi Y, Kume A, Li M, Doyu M, Hata M, Ohtsuka K, Sobue G 2000 Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract. J Biol Chem 275:8772-8778
-
(2000)
J Biol Chem
, vol.275
, pp. 8772-8778
-
-
Kobayashi, Y.1
Kume, A.2
Li, M.3
Doyu, M.4
Hata, M.5
Ohtsuka, K.6
Sobue, G.7
-
44
-
-
0031939924
-
A cell culture model for androgen effects in motor neurons
-
Brooks BP, Merry DE, Paulson HL, Lieberman AP, Kolson DL, Fischbeck KH 1998 A cell culture model for androgen effects in motor neurons. J Neurochem 70:1054-1060
-
(1998)
J Neurochem
, vol.70
, pp. 1054-1060
-
-
Brooks, B.P.1
Merry, D.E.2
Paulson, H.L.3
Lieberman, A.P.4
Kolson, D.L.5
Fischbeck, K.H.6
-
45
-
-
13244275404
-
Androgen-induced neurite outgrowth is mediated by neuritin in motor neurones
-
Marron TU, Guerini V, Rusmini P, Sau D, Brevini TA, Martini L, Poletti A 2005 Androgen-induced neurite outgrowth is mediated by neuritin in motor neurones. J Neurochem 92:10-20
-
(2005)
J Neurochem
, vol.92
, pp. 10-20
-
-
Marron, T.U.1
Guerini, V.2
Rusmini, P.3
Sau, D.4
Brevini, T.A.5
Martini, L.6
Poletti, A.7
-
46
-
-
0034884320
-
Androgen-induced up-regula-tion of tubulin isoforms in neuroblastoma cells
-
Butler R, Leigh PN, Gallo JM 2001 Androgen-induced up-regula-tion of tubulin isoforms in neuroblastoma cells. J Neurochem 78: 854-861
-
(2001)
J Neurochem
, vol.78
, pp. 854-861
-
-
Butler, R.1
Leigh, P.N.2
Gallo, J.M.3
-
47
-
-
0141736846
-
Androgen receptors containing expanded polyglutamine tracts exhibit progressive toxicity when stably expressed in the neuroblastoma cell line, SH-SY 5Y
-
Avila DM, Allman DR, Gallo JM, McPhaul MJ 2003 Androgen receptors containing expanded polyglutamine tracts exhibit progressive toxicity when stably expressed in the neuroblastoma cell line, SH-SY 5Y. Exp Biol Med (Maywood) 228:982-990
-
(2003)
Exp Biol Med (Maywood)
, vol.228
, pp. 982-990
-
-
Avila, D.M.1
Allman, D.R.2
Gallo, J.M.3
McPhaul, M.J.4
-
48
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DiFiglia M, Sapp E, Chase KO, Davies SW, Bates GP, Vonsattel JP, Aronin N 1997 Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277:1990-1993
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
49
-
-
0032486433
-
Teratogen-mediated inhibition of target tissue response to Shh signaling
-
Cooper MK, Porter JA, Young KE, Beachy PA 1998 Teratogen-mediated inhibition of target tissue response to Shh signaling. Science 280:1603-1607
-
(1998)
Science
, vol.280
, pp. 1603-1607
-
-
Cooper, M.K.1
Porter, J.A.2
Young, K.E.3
Beachy, P.A.4
-
51
-
-
0035918165
-
Caveo-lin-1 interacts with androgen receptor. A positive modulator of androgen receptor mediated transactivation
-
Lu ML, Schneider MC, Zheng Y, Zhang X, Richie JP 2001 Caveo-lin-1 interacts with androgen receptor. A positive modulator of androgen receptor mediated transactivation. J Biol Chem 276: 13442-13451
-
(2001)
J Biol Chem
, vol.276
, pp. 13442-13451
-
-
Lu, M.L.1
Schneider, M.C.2
Zheng, Y.3
Zhang, X.4
Richie, J.P.5
-
52
-
-
34548656928
-
Non-genomic activity of ligands in the association of androgen receptor with SRC
-
Kim SB, Kanno A, Ozawa T, Tao H, Umezawa Y 2007 Non-genomic activity of ligands in the association of androgen receptor with SRC. ACS Chem Biol 2:484-492
-
(2007)
ACS Chem Biol
, vol.2
, pp. 484-492
-
-
Kim, S.B.1
Kanno, A.2
Ozawa, T.3
Tao, H.4
Umezawa, Y.5
-
53
-
-
0035831020
-
Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: Dissociation from transcriptional activity
-
Kousteni S, Bellido T, Plotkin LI, O'Brien CA, Bodenner DL, Han L, Han K, DiGregorio GB, Katzenellenbogen JA, Katzenellenbogen BS, Roberson PK, Weinstein RS, Jilka RL, Manolagas SC 2001 Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity. Cell 104:719-730
-
(2001)
Cell
, vol.104
, pp. 719-730
-
-
Kousteni, S.1
Bellido, T.2
Plotkin, L.I.3
O'Brien, C.A.4
Bodenner, D.L.5
Han, L.6
Han, K.7
Digregorio, G.B.8
Katzenellenbogen, J.A.9
Katzenellenbogen, B.S.10
Roberson, P.K.11
Weinstein, R.S.12
Jilka, R.L.13
Manolagas, S.C.14
-
54
-
-
0034675994
-
Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
-
Migliaccio A, Castoria G, Di Domenico M, de Falco A, Bilancio A, Lombardi M, Barone MV, Ametrano D, Zannini MS, Abbondanza C, Auricchio F 2000 Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation. EMBO J 19:5406-5417
-
(2000)
EMBO J
, vol.19
, pp. 5406-5417
-
-
Migliaccio, A.1
Castoria, G.2
di Domenico, M.3
de Falco, A.4
Bilancio, A.5
Lombardi, M.6
Barone, M.V.7
Ametrano, D.8
Zannini, M.S.9
Abbondanza, C.10
Auricchio, F.11
-
55
-
-
36048996570
-
Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway
-
Das M, Scappini E, Martin NP, Wong KA, Dunn S, Chen YJ, Miller SL, Domin J, O'Bryan JP 2007 Regulation of neuron survival through an intersectin-phosphoinositide 3'-kinase C2beta-AKT pathway. Mol Cell Biol 27:7906-7917
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7906-7917
-
-
Das, M.1
Scappini, E.2
Martin, N.P.3
Wong, K.A.4
Dunn, S.5
Chen, Y.J.6
Miller, S.L.7
Domin, J.8
O'Bryan, J.P.9
-
56
-
-
26944431588
-
Akt/Bad signaling and motor neuron survival after spinal cord injury
-
Yu F, Sugawara T, Maier CM, Hsieh LB, Chan PH 2005 Akt/Bad signaling and motor neuron survival after spinal cord injury. Neu-robiol Dis 20:491-499
-
(2005)
Neu-robiol Dis
, vol.20
, pp. 491-499
-
-
Yu, F.1
Sugawara, T.2
Maier, C.M.3
Hsieh, L.B.4
Chan, P.H.5
-
57
-
-
0030948745
-
Trafficking of the androgen receptor in living cells with fused green fluorescent protein-androgen receptor
-
Georget V, Lobaccaro JM, Terouanne B, Mangeat P, Nicolas JC, Sultan C 1997 Trafficking of the androgen receptor in living cells with fused green fluorescent protein-androgen receptor. Mol Cell Endocrinol 129:17-26
-
(1997)
Mol Cell Endocrinol
, vol.129
, pp. 17-26
-
-
Georget, V.1
Lobaccaro, J.M.2
Terouanne, B.3
Mangeat, P.4
Nicolas, J.C.5
Sultan, C.6
-
58
-
-
22244455430
-
The structural basis of androgen receptor activation: Intramolecular and intermolecular amino-carboxy interactions
-
Schaufele F, Carbonell X, Guerbadot M, Borngraeber S, Chapman MS, Ma AA, Miner JN, Diamond MI 2005 The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions. Proc Natl Acad Sci USA 102:9802-9807
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 9802-9807
-
-
Schaufele, F.1
Carbonell, X.2
Guerbadot, M.3
Borngraeber, S.4
Chapman, M.S.5
Ma, A.A.6
Miner, J.N.7
Diamond, M.I.8
-
59
-
-
33750614913
-
The bright side of JNKs-Multitalented mediators in neuronal sprouting, brain development and nerve fiber regeneration
-
Waetzig V, Zhao Y, Herdegen T 2006 The bright side of JNKs-Multitalented mediators in neuronal sprouting, brain development and nerve fiber regeneration. Prog Neurobiol 80:84-97
-
(2006)
Prog Neurobiol
, vol.80
, pp. 84-97
-
-
Waetzig, V.1
Zhao, Y.2
Herdegen, T.3
-
60
-
-
77953509165
-
Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration
-
Barnat M, Enslen H, Propst F, Davis RJ, Soares S, Nothias F 2010 Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration. J Neurosci 30: 7804-7816
-
(2010)
J Neurosci
, vol.30
, pp. 7804-7816
-
-
Barnat, M.1
Enslen, H.2
Propst, F.3
Davis, R.J.4
Soares, S.5
Nothias, F.6
-
61
-
-
0042170262
-
Characterization of the species- and stage-specificity of two monoclonal antibodies against Leishmania amazonensis
-
Chaves CS, Soares DC, Da Silva RP, Saraiva EM 2003 Characterization of the species- and stage-specificity of two monoclonal antibodies against Leishmania amazonensis. Exp Parasitol 103:152-159
-
(2003)
Exp Parasitol
, vol.103
, pp. 152-159
-
-
Chaves, C.S.1
Soares, D.C.2
da Silva, R.P.3
Saraiva, E.M.4
-
62
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame S, Cohen P 2001 GSK3 takes centre stage more than 20 years after its discovery. Biochem J 359:1-16
-
(2001)
Biochem J
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
63
-
-
34447309577
-
Akt blocks ligand binding and protects against expanded polyglutamine androgen receptor toxicity
-
Palazzolo I, Burnett BG, Young JE, Brenne PL, La Spada AR, Fis-chbeck KH, Howell BW, Pennuto M 2007 Akt blocks ligand binding and protects against expanded polyglutamine androgen receptor toxicity. Hum Mol Genet 16:1593-1603
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1593-1603
-
-
Palazzolo, I.1
Burnett, B.G.2
Young, J.E.3
Brenne, P.L.4
la Spada, A.R.5
Fis-Chbeck, K.H.6
Howell, B.W.7
Pennuto, M.8
-
64
-
-
22244476115
-
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
-
Wei W, Jin J, Schlisio S, Harper JW, Kaelin Jr WG 2005 The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase. Cancer Cell 8:25-33
-
(2005)
Cancer Cell
, vol.8
, pp. 25-33
-
-
Wei, W.1
Jin, J.2
Schlisio, S.3
Harper, J.W.4
Kaelin, W.G.5
-
65
-
-
0041524094
-
A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun
-
Morton S, Davis RJ, McLaren A, Cohen P 2003 A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun. EMBO J 22:3876-3886
-
(2003)
EMBO J
, vol.22
, pp. 3876-3886
-
-
Morton, S.1
Davis, R.J.2
McLaren, A.3
Cohen, P.4
-
66
-
-
33746077664
-
Pathogenesis, animal models and therapeutics in spinal and bulbar muscular atrophy (SBMA)
-
Katsuno M, Adachi H, Waza M, Banno H, Suzuki K, Tanaka F, Doyu M, Sobue G 2006 Pathogenesis, animal models and therapeutics in spinal and bulbar muscular atrophy (SBMA). Exp Neurol 200:8-18
-
(2006)
Exp Neurol
, vol.200
, pp. 8-18
-
-
Katsuno, M.1
Adachi, H.2
Waza, M.3
Banno, H.4
Suzuki, K.5
Tanaka, F.6
Doyu, M.7
Sobue, G.8
-
67
-
-
0038714285
-
Leuprorelin rescues polyglu-tamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy
-
Katsuno M, Adachi H, Doyu M, Minamiyama M, Sang C, Ko-bayashi Y, Inukai A, Sobue G 2003 Leuprorelin rescues polyglu-tamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy. Nat Med 9:768-773
-
(2003)
Nat Med
, vol.9
, pp. 768-773
-
-
Katsuno, M.1
Adachi, H.2
Doyu, M.3
Minamiyama, M.4
Sang, C.5
Ko-Bayashi, Y.6
Inukai, A.7
Sobue, G.8
-
68
-
-
33748787116
-
Ligand-independent androgen receptor activity is activation function-2-independent and resistant to anti-androgens in androgen refractory prostate cancer cells
-
Dehm SM, Tindall DJ 2006 Ligand-independent androgen receptor activity is activation function-2-independent and resistant to anti-androgens in androgen refractory prostate cancer cells. J Biol Chem 281:27882-27893
-
(2006)
J Biol Chem
, vol.281
, pp. 27882-27893
-
-
Dehm, S.M.1
Tindall, D.J.2
-
69
-
-
0035496220
-
The development of androgen-inde-pendent prostate cancer
-
Feldman BJ, Feldman D 2001 The development of androgen-inde-pendent prostate cancer. Nature reviews 1:34-45
-
(2001)
Nature Reviews
, vol.1
, pp. 34-45
-
-
Feldman, B.J.1
Feldman, D.2
-
70
-
-
0042315340
-
Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells
-
Estrada M, Espinosa A, Müller M, Jaimovich E 2003 Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells. Endocrinology 144:3586-3597
-
(2003)
Endocrinology
, vol.144
, pp. 3586-3597
-
-
Estrada, M.1
Espinosa, A.2
Müller, M.3
Jaimovich, E.4
-
71
-
-
0028290639
-
Androgens increase intracellular calcium concentration and inositol 1,4,5-trisphosphate and diacyl-glycerol formation via a pertussis toxin-sensitive G-protein
-
Lieberherr M, Grosse B 1994 Androgens increase intracellular calcium concentration and inositol 1,4,5-trisphosphate and diacyl-glycerol formation via a pertussis toxin-sensitive G-protein. J Biol Chem 269:7217-7223
-
(1994)
J Biol Chem
, vol.269
, pp. 7217-7223
-
-
Lieberherr, M.1
Grosse, B.2
|