Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

EMBO Journal

Volumn 21, Issue 15, 2002, Pages 4037-4048

  Lin, Hui Kuan ^a   Wang, Liang ^a   Hu, Yueh Chiang ^a   Altuwaijri, Saleh ^a   Chang, Chawnshang ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Androgen receptor; E3 ligase; Phosphorylation; Proteasome; Ubiquitylation

Indexed keywords

ANDROGEN RECEPTOR; GLUTATHIONE TRANSFERASE; LIGASE; PROTEASOME; PROTEIN KINASE B; TRANSCRIPTION FACTOR; UBIQUITIN;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL CYCLE; ENZYME PHOSPHORYLATION; GENETIC TRANSCRIPTION; IMMUNOCYTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COLONY-FORMING UNITS ASSAY; ENZYME ACTIVATION; FIBROBLASTS; LIGASES; MACROMOLECULAR SUBSTANCES; MICE; NUCLEAR PROTEINS; PEPTIDE HYDROLASES; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN INTERACTION MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MDM2; RATS; RECEPTORS, ANDROGEN; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION, GENETIC; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA;

EID: 0036683093     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf406     Document Type: Article

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