Signalling danger: Endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

Diabetologia

Volumn 56, Issue 2, 2013, Pages 234-241

  Eizirik, D L ^a   Miani, M ^a   Cardozo, A K ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Cytokines; Diabetes; Endoplasmic reticulum stress; ER stress; Inflammation; Innate immunity; Pancreatic beta cells; Pancreatic islets; Review; Type 1 diabetes

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN HOMOLOGOUS PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROINSULIN; PROTEIN IRE1; PROTEIN KINASE R; PROTEIN KINASE R LIKE ER KINASE; SATURATED FATTY ACID; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

CELL DEATH; CHILDHOOD OBESITY; ENDOPLASMIC RETICULUM STRESS; HUMAN; INFLAMMATION; INNATE IMMUNITY; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; MOLECULAR INTERACTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PREVALENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROCESSING; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; ANIMAL; GENETICS; METABOLISM; PANCREAS ISLET; PHYSIOLOGY;

ANIMALS; ENDOPLASMIC RETICULUM STRESS; HUMANS; ISLETS OF LANGERHANS; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

MLCS; MLOWN;

EID: 84878777666     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2762-3     Document Type: Review

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