Mild endoplasmic reticulum stress augments the proinflammatory effect of IL-1β in pancreatic rat β-cells via the IRE1α/XBP1s pathway

Endocrinology

Volumn 153, Issue 7, 2012, Pages 3017-3028

  Miani, Michela ^a   Colli, Maikel L ^a   Ladrière, Laurence ^a   Cnop, Miriam ^a   Eizirik, Decio L ^a  

^a ERASME HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CXCL1 CHEMOKINE; CYCLOPIAZONIC ACID; FAS ANTIGEN; FATTY ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INOSITOL; INOSITOL REQUIRING ENZYME 1ALPHA; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; SMALL INTERFERING RNA; SYNAPTOTAGMIN I; TRANSCRIPTION FACTOR FKHR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE PREDISPOSITION; ENDOPLASMIC RETICULUM STRESS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE EXPRESSION; GENE TARGETING; IMMUNOFLUORESCENCE; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; GENES, REPORTER; INFLAMMATION; INSULIN-SECRETING CELLS; INSULINOMA; INTERLEUKIN-1BETA; MALE; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, WISTAR; RNA INTERFERENCE; TRANSCRIPTION FACTORS;

EID: 84862742723     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-2090     Document Type: Article

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