-
1
-
-
82955233157
-
The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks
-
Acs, K., Luijsterburg, M. S., Ackermann, L, Salomons, F. A., Hoppe, T., and Dantuma, N. P. (2011). The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks. Nat. Struct Mol. Biol. 18, 1345-1350.
-
(2011)
Nat. Struct Mol. Biol.
, vol.18
, pp. 1345-1350
-
-
Acs, K.1
Luijsterburg, M.S.2
Ackermann, L.3
Salomons, F.A.4
Hoppe, T.5
Dantuma, N.P.6
-
2
-
-
79959947909
-
Chromatin response to DNA double-strand break damage
-
Bao, Y. (2011). Chromatin response to DNA double-strand break damage. Epigenomics 3, 307-321.
-
(2011)
Epigenomics
, vol.3
, pp. 307-321
-
-
Bao, Y.1
-
3
-
-
0032504021
-
Structure determination of the small ubiquitin-related modifier SUMO-1
-
Bayer, P., Arndt, A., Metzger, S., Mahajan, R., Melchior, E, Jaenicke, R., et al. (1998). Structure determination of the small ubiquitin-related modifier SUMO-1.J. Mol. Biol. 280, 275-286.
-
(1998)
J. Mol. Biol.
, vol.280
, pp. 275-286
-
-
Bayer, P.1
Arndt, A.2
Metzger, S.3
Mahajan, R.4
Melchior, E.5
Jaenicke, R.6
-
4
-
-
78649450619
-
Assembly and function of DNA double-strand break repair foci in mammalian cells
-
Bekker-Jensen, S., and Mailand, N. (2010). Assembly and function of DNA double-strand break repair foci in mammalian cells. DNA Repair (Amst)9, 1219-1228.
-
(2010)
DNA Repair (Amst)
, vol.9
, pp. 1219-1228
-
-
Bekker-Jensen, S.1
Mailand, N.2
-
5
-
-
80155198826
-
Recognition of UbcH5c and the nucleosome by the Bmil/Ringlb ubiquitin ligase complex
-
Bentley, M. L., Corn, J. E., Dong, K. C, Phung, Q., Cheung, T. K., and Cochran, A. G. (2011). Recognition of UbcH5c and the nucleosome by the Bmil/Ringlb ubiquitin ligase complex. EMBO J. 30, 3285-3297.
-
(2011)
EMBO J
, vol.30
, pp. 3285-3297
-
-
Bentley, M.L.1
Corn, J.E.2
Dong, K.C.3
Phung, Q.4
Cheung, T.K.5
Cochran, A.G.6
-
6
-
-
33646584518
-
DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A
-
Bergink, S., Salomons, F. A., Hoogstraten, D., Groothuis, T. A., de Waard, H., Wu, J., et al. (2006). DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A. Genes Dev. 20, 1343-1352.
-
(2006)
Genes Dev
, vol.20
, pp. 1343-1352
-
-
Bergink, S.1
Salomons, F.A.2
Hoogstraten, D.3
Groothuis, T.A.4
de Waard, H.5
Wu, J.6
-
7
-
-
36448975490
-
Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies
-
Bernardi, R., and Pandolfi, P. P. (2007). Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies. Nat. Rev. Mol. Cell Biol. 8, 1006-1016.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 1006-1016
-
-
Bernardi, R.1
Pandolfi, P.P.2
-
8
-
-
84855258476
-
Role of histone tails in structural stability of the nucleosome
-
doi: 10.1371/journal.pcbi. 1002279
-
Biswas, M., Voltz, K., Smith, J. C, and Langowski, J. (2011). Role of histone tails in structural stability of the nucleosome. PLoS Cotnput. Biol. 7:el002279. doi: 10.1371/journal.pcbi. 1002279
-
(2011)
PLoS Cotnput. Biol.
, vol.7
-
-
Biswas, M.1
Voltz, K.2
Smith, J.C.3
Langowski, J.4
-
9
-
-
84871962551
-
Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924
-
Blank, J. L., Liu, X. J., Cosmopoulos, K., Bouck, D. C, Garcia, K., Bernard, H., et al. (2013). Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924. Cancer Res. 73,225-234.
-
(2013)
Cancer Res
, vol.73
, pp. 225-234
-
-
Blank, J.L.1
Liu, X.J.2
Cosmopoulos, K.3
Bouck, D.C.4
Garcia, K.5
Bernard, H.6
-
10
-
-
3042644131
-
A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus
-
Bohren, K. M., Nadkarni, V., Song, J. H., Gabbay, K. H., and Owerbach, D. (2004). A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus.J. Biol. Chem. 279, 27233-27238.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27233-27238
-
-
Bohren, K.M.1
Nadkarni, V.2
Song, J.H.3
Gabbay, K.H.4
Owerbach, D.5
-
11
-
-
77951057068
-
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
-
Bothmer, A., Robbiani, D. E, Feldhahn, N., Gazumyan, A., Nussenzweig, A., and Nussenzweig, M. C. (2010). 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.J. Exp. Med. 207, 855-865.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 855-865
-
-
Bothmer, A.1
Robbiani, D.E.2
Feldhahn, N.3
Gazumyan, A.4
Nussenzweig, A.5
Nussenzweig, M.C.6
-
12
-
-
77953291328
-
53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers
-
Bouwman, P., Aly, A., Escandell, J. M., Pieterse, M., Bartkova, J., van der Gulden, H., et al. (2010). 53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat. Struct. Mol. Biol. 17, 688-695.
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 688-695
-
-
Bouwman, P.1
Aly, A.2
Escandell, J.M.3
Pieterse, M.4
Bartkova, J.5
van der Gulden, H.6
-
13
-
-
33745753378
-
Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmil andRinglb
-
Buchwald, G., van der Stoop, P., Weichenrieder, O., Perrakis, A., van Lohuizen, M., and Sixma, T. K. (2006). Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmil andRinglb. EMBO J.25,2465-2474.
-
(2006)
EMBO J.
, vol.25
, pp. 2465-2474
-
-
Buchwald, G.1
van der Stoop, P.2
Weichenrieder, O.3
Perrakis, A.4
van Lohuizen, M.5
Sixma, T.K.6
-
14
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brcal-deficient cells by blocking resection of DNA breaks
-
Bunting, S. F., Callen, E., Wong, N., Chen, H. T., Polato, E, Gunn, A., et al. (2010). 53BP1 inhibits homologous recombination in Brcal-deficient cells by blocking resection of DNA breaks. Cell 141, 243-254.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callen, E.2
Wong, N.3
Chen, H.T.4
Polato, E.5
Gunn, A.6
-
15
-
-
84867101138
-
The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response
-
Butler, L. R., Densham, R. M., Jia, J., Garvin, A. J., Stone, H. R., Shah, V., et al. (2012). The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response. EMBO J. 31, 3918-3934.
-
(2012)
EMBO J
, vol.31
, pp. 3918-3934
-
-
Butler, L.R.1
Densham, R.M.2
Jia, J.3
Garvin, A.J.4
Stone, H.R.5
Shah, V.6
-
16
-
-
29144487990
-
Role of Bmi-1 and RinglA in H2A ubiquitylation and Hox gene silencing
-
Cao, R., Tsukada, Y., and Zhang, Y. (2005). Role of Bmi-1 and RinglA in H2A ubiquitylation and Hox gene silencing. Mol. Cell 20, 845-854.
-
(2005)
Mol. Cell
, vol.20
, pp. 845-854
-
-
Cao, R.1
Tsukada, Y.2
Zhang, Y.3
-
17
-
-
84864977706
-
Ring finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damage
-
Chen, J., Feng, W., Jiang, J., Deng, Y, and Huen, M. S. (2012). Ring finger protein RNF169 antagonizes the ubiquitin-dependent signaling cascade at sites of DNA damage.J. Biol. Chem. 287,27715-27722.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 27715-27722
-
-
Chen, J.1
Feng, W.2
Jiang, J.3
Deng, Y.4
Huen, M.S.5
-
18
-
-
77958102720
-
Deficiency in Brel impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells
-
Chernikova, S. B., Dorth, J. A., Razorenova, O. V., Game, J. C, and Brown, J. M. (2010). Deficiency in Brel impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells. Radiat. Res. 174, 558-565.
-
(2010)
Radiat. Res.
, vol.174
, pp. 558-565
-
-
Chernikova, S.B.1
Dorth, J.A.2
Razorenova, O.V.3
Game, J.C.4
Brown, J.M.5
-
19
-
-
78649336706
-
The DNA damage response: making it safe to play with knives
-
Ciccia, A., and Elledge, S. J. (2010). The DNA damage response: making it safe to play with knives. Mol. Cell 40, 179-204.
-
(2010)
Mol. Cell
, vol.40
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
20
-
-
84884333239
-
Sumo paralogs: redundancy and divergencies
-
Citro, S., and Chiocca, S. (2013). Sumo paralogs: redundancy and divergencies. Front. Biosci. (Schol Ed) 5, 544-553.
-
(2013)
Front. Biosci. (Schol Ed)
, vol.5
, pp. 544-553
-
-
Citro, S.1
Chiocca, S.2
-
21
-
-
79953869356
-
The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
-
Coleman, K. A., and Greenberg, R. A. (2011). The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection.J. Biol. Chem. 286,13669-13680.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13669-13680
-
-
Coleman, K.A.1
Greenberg, R.A.2
-
22
-
-
62649104153
-
K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Pohl
-
Cooper, E. M., Cutcliffe, C, Kristiansen, T. Z., Pandey, A., Pickart, C. M., and Cohen, R. E. (2009). K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Pohl. EMBO J. 28, 621-631.
-
(2009)
EMBO J
, vol.28
, pp. 621-631
-
-
Cooper, E.M.1
Cutcliffe, C.2
Kristiansen, T.Z.3
Pandey, A.4
Pickart, C.M.5
Cohen, R.E.6
-
23
-
-
33746747016
-
Chromatin modulation and the DNA damage response
-
Costelloe, T., Fitzgerald, J., Murphy, N. J., Flaus, A., and Lowndes, N. E (2006). Chromatin modulation and the DNA damage response. Exp. Cell Res. 312,2677-2686.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 2677-2686
-
-
Costelloe, T.1
Fitzgerald, J.2
Murphy, N.J.3
Flaus, A.4
Lowndes, N.E.5
-
24
-
-
84861941745
-
DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger
-
Danielsen, J. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, J., Wikstrom, M., et al. (2012). DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger. J. Cell Biol. 197, 179-187.
-
(2012)
J. Cell Biol.
, vol.197
, pp. 179-187
-
-
Danielsen, J.R.1
Povlsen, L.K.2
Villumsen, B.H.3
Streicher, W.4
Nilsson, J.5
Wikstrom, M.6
-
25
-
-
4644351274
-
PML nuclear bodies: dynamic sensors of DNA damage and cellular stress
-
Dellaire, G., and Bazett-Jones, D. P. (2004). PML nuclear bodies: dynamic sensors of DNA damage and cellular stress. Bioessays 26, 963-977.
-
(2004)
Bioessays
, vol.26
, pp. 963-977
-
-
Dellaire, G.1
Bazett-Jones, D.P.2
-
26
-
-
33749547681
-
Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR
-
Dellaire, G., Ching, R. W., Ahmed, K., Jalali, E, Tse, K. C, Bristow, R. G., et al. (2006). Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR.J. Cell Biol. 175, 55-66.
-
(2006)
J. Cell Biol.
, vol.175
, pp. 55-66
-
-
Dellaire, G.1
Ching, R.W.2
Ahmed, K.3
Jalali, E.4
Tse, K.C.5
Bristow, R.G.6
-
27
-
-
70449940264
-
High resolution imaging of changes in the structure and spatial organization of chromatin, gamma-H2A, X and the MRN complex within etoposide-induced DNA repair foci
-
Dellaire, G., Kepkay, R., and Bazett-Jones, D. P. (2009). High resolution imaging of changes in the structure and spatial organization of chromatin, gamma-H2A.X and the MRN complex within etoposide-induced DNA repair foci. Cell Cycle 8, 3750-3769.
-
(2009)
Cell Cycle
, vol.8
, pp. 3750-3769
-
-
Dellaire, G.1
Kepkay, R.2
Bazett-Jones, D.P.3
-
28
-
-
34547856653
-
The human Mi-2/NuRD complex and gene regulation
-
Denslow, S. A., and Wade, P. A. (2007). The human Mi-2/NuRD complex and gene regulation. Oncogene 26, 5433-5438.
-
(2007)
Oncogene
, vol.26
, pp. 5433-5438
-
-
Denslow, S.A.1
Wade, P.A.2
-
29
-
-
49849102784
-
ISG15 as a novel tumor biomarker for drug sensitivity
-
Desai, S. D., Wood, L. M., Tsai, Y C, Hsieh, T. S., Marks, J. R., Scott, G. L., et al. (2008). ISG15 as a novel tumor biomarker for drug sensitivity. Mol. Cancer Ther. 7,1430-1439.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1430-1439
-
-
Desai, S.D.1
Wood, L.M.2
Tsai, Y.C.3
Hsieh, T.S.4
Marks, J.R.5
Scott, G.L.6
-
30
-
-
70349441058
-
Ubiquitin-binding domains - from structures to functions
-
Dikic, I., Wakatsuki, S., and Walters, K. J. (2009). Ubiquitin-binding domains - from structures to functions. Nat. Rev. Mol. Cell Biol. 10, 659-671.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 659-671
-
-
Dikic, I.1
Wakatsuki, S.2
Walters, K.J.3
-
31
-
-
67649509979
-
Chromatin structure and DNA damage repair
-
Dinant, C, Houtsmuller, A. B., and Vermeulen, W. (2008). Chromatin structure and DNA damage repair. Epigenetics Chromatin 1, 9.
-
(2008)
Epigenetics Chromatin
, vol.1
, pp. 9
-
-
Dinant, C.1
Houtsmuller, A.B.2
Vermeulen, W.3
-
32
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil, C, Mailand, N., Bekker-Jensen, S., Menard, P., Larsen, D. H., Pepperkok, R., et al. (2009). RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 136,435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
-
33
-
-
77955475870
-
Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex
-
Dou, H., Huang, C, Singh, M., Carpenter, P. B., and Yeh, E. T. (2010). Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. Mol. Cell 39, 333-345.
-
(2010)
Mol. Cell
, vol.39
, pp. 333-345
-
-
Dou, H.1
Huang, C.2
Singh, M.3
Carpenter, P.B.4
Yeh, E.T.5
-
34
-
-
10944267160
-
Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites
-
Downs, J. A., Allard, S., Jobin-Robitaille, O., Javaheri, A., Auger, A., Bouchard, N., et al. (2004). Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites. Mol. Cell 16, 979-990.
-
(2004)
Mol. Cell
, vol.16
, pp. 979-990
-
-
Downs, J.A.1
Allard, S.2
Jobin-Robitaille, O.3
Javaheri, A.4
Auger, A.5
Bouchard, N.6
-
35
-
-
33749506057
-
Mms2-Ubcl3 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyu-biquitin chain formation
-
Eddins, M. J., Carlile, C. M., Gomez, K. M., Pickart, C. M., and Wolberger, C. (2006). Mms2-Ubcl3 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyu-biquitin chain formation. Nat. Struct. Mol. Biol. 13,915-920.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 915-920
-
-
Eddins, M.J.1
Carlile, C.M.2
Gomez, K.M.3
Pickart, C.M.4
Wolberger, C.5
-
36
-
-
84876877091
-
Acellcycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtlP controls DNA repair pathway choice
-
Escribano-Diaz, C, Orthwein, A., Fradet-Turcotte, A., Xing, M., Young, J. T., Tkac, J., et al. (2013).Acellcycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtlP controls DNA repair pathway choice. Mol. Cell 49, 872-883.
-
(2013)
Mol. Cell
, vol.49
, pp. 872-883
-
-
Escribano-Diaz, C.1
Orthwein, A.2
Fradet-Turcotte, A.3
Xing, M.4
Young, J.T.5
Tkac, J.6
-
37
-
-
77955381770
-
BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery
-
Facchino, S., Abdouh, M., Chatoo, W, and Bernier, G. (2010). BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery.J. Neurosci. 30, 10096-10111.
-
(2010)
J. Neurosci.
, vol.30
, pp. 10096-10111
-
-
Facchino, S.1
Abdouh, M.2
Chatoo, W.3
Bernier, G.4
-
38
-
-
84862777619
-
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
-
Feng, L., and Chen, J. (2012). The E3 ligase RNF8 regulates KU80 removal and NHEJ repair. Nat. Struct. Mol. Biol. 19,201-206.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 201-206
-
-
Feng, L.1
Chen, J.2
-
39
-
-
78751515133
-
Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction
-
Fierz, B., Chatterjee, C, McGinty, R. K., Bar-Dagan, M., Raleigh, D. P., and Muir, T. W (2011). Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction. Nat. Chem. Biol. 7,113-119.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 113-119
-
-
Fierz, B.1
Chatterjee, C.2
McGinty, R.K.3
Bar-Dagan, M.4
Raleigh, D.P.5
Muir, T.W.6
-
40
-
-
84861765707
-
RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair
-
Galanty, Y, Belotserkovskaya, R., Coates, J., and Jackson, S. P. (2012). RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair. Genes Dev. 26, 1179-1195.
-
(2012)
Genes Dev
, vol.26
, pp. 1179-1195
-
-
Galanty, Y.1
Belotserkovskaya, R.2
Coates, J.3
Jackson, S.P.4
-
41
-
-
72449175818
-
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
-
Galanty, Y., Belotserkovskaya, R., Coates, J., Polo, S., Miller, K. M., and Jackson, S. P. (2009). Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature 462, 935-939.
-
(2009)
Nature
, vol.462
, pp. 935-939
-
-
Galanty, Y.1
Belotserkovskaya, R.2
Coates, J.3
Polo, S.4
Miller, K.M.5
Jackson, S.P.6
-
42
-
-
78649396592
-
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
-
Gareau, J. R., and Lima, C. D. (2010). The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition. Nat. Rev. Mol. Cell Biol. 11, 861-871.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 861-871
-
-
Gareau, J.R.1
Lima, C.D.2
-
43
-
-
84863793933
-
A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
-
Gatti, M., Pinato, S., Maspero, E., Soffientini, P., Polo, S., and Penengo, L. (2012). A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase. Cell Cycle 11, 2538-2544.
-
(2012)
Cell Cycle
, vol.11
, pp. 2538-2544
-
-
Gatti, M.1
Pinato, S.2
Maspero, E.3
Soffientini, P.4
Polo, S.5
Penengo, L.6
-
44
-
-
44649122151
-
Role of histone modifications in defining chromatin structure and function
-
Gelato, K. A., and Fischle, W. (2008). Role of histone modifications in defining chromatin structure and function. Biol. Chetn. 389, 353-363.
-
(2008)
Biol. Chetn.
, vol.389
, pp. 353-363
-
-
Gelato, K.A.1
Fischle, W.2
-
45
-
-
79956086415
-
BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair
-
Ginjala,V.,Nacerddine, K., Kulkarni, A., Oza, J., Hill, S. J.,Yao, M., et al. (2011). BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Mol. Cell. Biol. 31, 1972-1982.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 1972-1982
-
-
Ginjala, V.1
Nacerddine, K.2
Kulkarni, A.3
Oza, J.4
Hill, S.J.5
Yao, M.6
-
46
-
-
79960055393
-
KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response
-
Goodarzi, A. A., Kurka, T., and Jeggo, P. A. (2011). KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. Nat. Struct. Mol. Biol. 18,831-839.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 831-839
-
-
Goodarzi, A.A.1
Kurka, T.2
Jeggo, P.A.3
-
47
-
-
47349107760
-
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
-
Goodarzi, A. A., Noon, A. T., Deckbar, D., Ziv, Y, Shiloh, Y, Lobrich, M., et al. (2008). ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Mol. Cell 31, 167-177.
-
(2008)
Mol. Cell
, vol.31
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Lobrich, M.6
-
48
-
-
33847076248
-
Chromatin challenges during DNA replication and repair
-
Groth, A., Rocha, W., Verreault, A., and Almouzni, G. (2007). Chromatin challenges during DNA replication and repair. Cell 128, 721-733.
-
(2007)
Cell
, vol.128
, pp. 721-733
-
-
Groth, A.1
Rocha, W.2
Verreault, A.3
Almouzni, G.4
-
49
-
-
3543046736
-
A functional variant of SUMO4, a new IicBa modifier, is associated with type 1 diabetes
-
Guo, D., Li, M., Zhang, Y., Yang, P., Eckenrode, S., Hopkins, D., et al. (2004). A functional variant of SUMO4, a new IicBa modifier, is associated with type 1 diabetes. Nat. Genet. 36, 837-841.
-
(2004)
Nat. Genet.
, vol.36
, pp. 837-841
-
-
Guo, D.1
Li, M.2
Zhang, Y.3
Yang, P.4
Eckenrode, S.5
Hopkins, D.6
-
50
-
-
84870760201
-
RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage
-
Guzzo, C. M., Berndsen, C. E., Zhu, J., Gupta, V., Datta, A., Greenberg, R. A., et al. (2012). RNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage. Sci. Signal. 5, ra88.
-
(2012)
Sci. Signal.
, vol.5
-
-
Guzzo, C.M.1
Berndsen, C.E.2
Zhu, J.3
Gupta, V.4
Datta, A.5
Greenberg, R.A.6
-
51
-
-
14244260623
-
Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae
-
Hannich, J. T., Lewis, A., Kroetz, M. B., Li, S. J., Heide, H., Emili, A., et al. (2005). Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J. Biol. Chetn. 280, 4102-4110.
-
(2005)
J. Biol. Chetn.
, vol.280
, pp. 4102-4110
-
-
Hannich, J.T.1
Lewis, A.2
Kroetz, M.B.3
Li, S.J.4
Heide, H.5
Emili, A.6
-
52
-
-
84870375549
-
Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks
-
doi: 10.1371/journal.pone.0049211
-
Hartlerode, A. J., Guan, Y, Rajendran, A., Ura, K., Schotta, G., Xie, A., et al. (2012). Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks. PLoS ONE 7:e49211. doi: 10.1371/journal.pone.0049211
-
(2012)
PLoS ONE
, vol.7
-
-
Hartlerode, A.J.1
Guan, Y.2
Rajendran, A.3
Ura, K.4
Schotta, G.5
Xie, A.6
-
53
-
-
33744940842
-
Specification of SUMO1- and SUMO2-interacting motifs
-
Hecker, C. M., Rabiller, M., Haglund, K., Bayer, P., and Dikic, I. (2006). Specification of SUMO1- and SUMO2-interacting motifs.J. Biol. Chem. 281, 16117-16127.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16117-16127
-
-
Hecker, C.M.1
Rabiller, M.2
Haglund, K.3
Bayer, P.4
Dikic, I.5
-
54
-
-
78651406669
-
H2AX prevents CtlP-mediated DNA end resection and aberrant repair in Gl -phase lymphocytes
-
Helmink, B. A., Tubbs, A. T., Dorsett, Y, Bednarski, J. J., Walker, L. M., Feng, Z., et al. (2011). H2AX prevents CtlP-mediated DNA end resection and aberrant repair in Gl -phase lymphocytes. Nature 469,245-249.
-
(2011)
Nature
, vol.469
, pp. 245-249
-
-
Helmink, B.A.1
Tubbs, A.T.2
Dorsett, Y.3
Bednarski, J.J.4
Walker, L.M.5
Feng, Z.6
-
55
-
-
23144452091
-
Ubiquitin-binding domains
-
Hicke, L., Schubert, H. L., and Hill, C. P. (2005). Ubiquitin-binding domains. Nat. Rev. Mol. Cell Biol. 6, 610-621.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 610-621
-
-
Hicke, L.1
Schubert, H.L.2
Hill, C.P.3
-
56
-
-
63649113699
-
Origin and function of ubiquitin-like proteins
-
Hochstrasser, M. (2009). Origin and function of ubiquitin-like proteins. Nature 458, 422-429.
-
(2009)
Nature
, vol.458
, pp. 422-429
-
-
Hochstrasser, M.1
-
57
-
-
0033525582
-
Noncanonical MMS2 encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
-
Hofmann, R. M., and Pickart, C. M. (1999). Noncanonical MMS2 encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell 96, 645-653.
-
(1999)
Cell
, vol.96
, pp. 645-653
-
-
Hofmann, R.M.1
Pickart, C.M.2
-
58
-
-
84864076551
-
Rap80 protein recruitment to DNA double-strand breaks requires binding to both small ubiquitin-like modifier (SUMO) and ubiquitin conjugates
-
Hu, X., Paul, A., and Wang, B. (2012). Rap80 protein recruitment to DNA double-strand breaks requires binding to both small ubiquitin-like modifier (SUMO) and ubiquitin conjugates.J. Biol. Chem. 287, 25510-25519.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 25510-25519
-
-
Hu, X.1
Paul, A.2
Wang, B.3
-
59
-
-
79954528832
-
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
-
Hu, Y, Scully, R., Sobhian, B., Xie, A., Shestakova, E., and Livingston, D. M. (2011). RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev. 25, 685-700.
-
(2011)
Genes Dev
, vol.25
, pp. 685-700
-
-
Hu, Y.1
Scully, R.2
Sobhian, B.3
Xie, A.4
Shestakova, E.5
Livingston, D.M.6
-
60
-
-
0029897210
-
Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent Gl arrest
-
Huang, L. C, Clarkin, K. C, and Wahl, G. M. (1996). Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent Gl arrest. Proc. Natl. Acad. Sci. U. S. A. 93, 4827-4832.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 4827-4832
-
-
Huang, L.C.1
Clarkin, K.C.2
Wahl, G.M.3
-
61
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen, M. S., Grant, R., Manke, I., Minn, K., Yu, X., Yaffe, M. B., et al. (2007). RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 131,901-914.
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
-
62
-
-
84861783400
-
Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions
-
Husnjak, K., and Dikic, I. (2012). Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions. Annu. Rev. Biochem. 81,291-322.
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 291-322
-
-
Husnjak, K.1
Dikic, I.2
-
63
-
-
77957748289
-
BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair
-
Ismail, I. H., Andrin, C, McDonald, D., and Hendzel, M. J. (2010). BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair. J. Cell Biol. 191,45-60.
-
(2010)
J. Cell Biol.
, vol.191
, pp. 45-60
-
-
Ismail, I.H.1
Andrin, C.2
McDonald, D.3
Hendzel, M.J.4
-
64
-
-
84863198650
-
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage
-
Ismail, I. H., Gagne, J. P., Caron, M. C, McDonald, D., Xu, Z., Masson, J. Y, et al. (2012). CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage. Nucleic Acids Res. 40, 5497-5510.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 5497-5510
-
-
Ismail, I.H.1
Gagne, J.P.2
Caron, M.C.3
McDonald, D.4
Xu, Z.5
Masson, J.Y.6
-
65
-
-
36749009119
-
PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing
-
Ivanov, A. V., Peng, H., Yurchenko, V., Yap, K. L., Negorev, D. G., Schultz, D. C, et al. (2007). PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing. Mol. Cell 28, 823-837.
-
(2007)
Mol. Cell
, vol.28
, pp. 823-837
-
-
Ivanov, A.V.1
Peng, H.2
Yurchenko, V.3
Yap, K.L.4
Negorev, D.G.5
Schultz, D.C.6
-
66
-
-
84863545539
-
Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15
-
Jeon, Y J., Jo, M. G., Yoo, H. M., Hong, S. H., Park, J. M., Ka, S. H., et al. (2012). Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15.J. Clin. Invest. 122, 2622-2636.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2622-2636
-
-
Jeon, Y.J.1
Jo, M.G.2
Yoo, H.M.3
Hong, S.H.4
Park, J.M.5
Ka, S.H.6
-
67
-
-
0030826334
-
Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p
-
Johnson, E. S., and Blobel, G. (1997). Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p.J. Biol. Chem. 272,26799-26802.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26799-26802
-
-
Johnson, E.S.1
Blobel, G.2
-
68
-
-
84864321774
-
Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase
-
Karanam, K., Kafri, R., Loewer, A., and Lahav, G. (2012). Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase. Mol. Cell 47, 320-329.
-
(2012)
Mol. Cell
, vol.47
, pp. 320-329
-
-
Karanam, K.1
Kafri, R.2
Loewer, A.3
Lahav, G.4
-
69
-
-
79551556884
-
KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin
-
Kepkay, R., Attwood, K. M., Ziv, Y., Shiloh, Y., and Dellaire, G. (2011). KAP1 depletion increases PML nuclear body number in concert with ultrastructural changes in chromatin. Cell Cycle 10, 308-322.
-
(2011)
Cell Cycle
, vol.10
, pp. 308-322
-
-
Kepkay, R.1
Attwood, K.M.2
Ziv, Y.3
Shiloh, Y.4
Dellaire, G.5
-
70
-
-
33749346301
-
Modification of proteins by ubiquitin and ubiquitin-like proteins
-
Kerscher, O., Felberbaum, R., and Hochstrasser, M. (2006). Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu. Rev. Cell Dev. Biol 22,159-180.
-
(2006)
Annu. Rev. Cell Dev. Biol
, vol.22
, pp. 159-180
-
-
Kerscher, O.1
Felberbaum, R.2
Hochstrasser, M.3
-
71
-
-
65249105512
-
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
-
Kim, J., Guermah, M., McGinty, R. K., Lee, J. S., Tang, Z., Milne, T. A., et al. (2009). RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 137, 459-471.
-
(2009)
Cell
, vol.137
, pp. 459-471
-
-
Kim, J.1
Guermah, M.2
McGinty, R.K.3
Lee, J.S.4
Tang, Z.5
Milne, T.A.6
-
72
-
-
28444463638
-
The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions
-
Kim, J., Hake, S. B., and Roeder, R. G. (2005). The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. Mol. Cell 20, 759-770.
-
(2005)
Mol. Cell
, vol.20
, pp. 759-770
-
-
Kim, J.1
Hake, S.B.2
Roeder, R.G.3
-
73
-
-
43049096803
-
Arsenic degrades PML or PML-RARa through a SUMO-triggered RNF4/ubiquitin-mediated pathway
-
Lallemand-Breitenbach, V., Jeanne, M., Benhenda, S., Nasr, R., Lei, M., Peres, L., et al. (2008). Arsenic degrades PML or PML-RARa through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat. Cell Biol. 10, 547-555.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 547-555
-
-
Lallemand-Breitenbach, V.1
Jeanne, M.2
Benhenda, S.3
Nasr, R.4
Lei, M.5
Peres, L.6
-
74
-
-
44349180168
-
Histone methyltransferase Dotl and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres
-
Lazzaro, E, Sapountzi, V., Granata, M., Pellicioli, A., Vaze, M., Haber, J. E., et al. (2008). Histone methyltransferase Dotl and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres. EMBO J. 27,1502-1512.
-
(2008)
EMBO J
, vol.27
, pp. 1502-1512
-
-
Lazzaro, E.1
Sapountzi, V.2
Granata, M.3
Pellicioli, A.4
Vaze, M.5
Haber, J.E.6
-
75
-
-
17644409069
-
ATM activation by DNA double-strand breaks through the Mrell-Rad50-Nbsl complex
-
Lee, J. H., and Paull, T. T. (2005). ATM activation by DNA double-strand breaks through the Mrell-Rad50-Nbsl complex. Science 308, 551-554.
-
(2005)
Science
, vol.308
, pp. 551-554
-
-
Lee, J.H.1
Paull, T.T.2
-
76
-
-
0019023314
-
High-resolution fractionation of nucleosomes: minor particles, whiskers and separation of mononucleosomes containing and lacking A24 semihistone
-
Levinger, L., and Varshavsky, A. (1980). High-resolution fractionation of nucleosomes: minor particles, "whiskers," and separation of mononucleosomes containing and lacking A24 semihistone. Proc. Natl. Acad. Sci. U.S.A. 77, 3244-3248.
-
(1980)
Proc. Natl. Acad. Sci. U. S. A.
, vol.77
, pp. 3244-3248
-
-
Levinger, L.1
Varshavsky, A.2
-
77
-
-
33847070442
-
The role of chromatin during transcription
-
Li, B., Carey, M., and Workman, J. L. (2007). The role of chromatin during transcription. Cell 128, 707-719.
-
(2007)
Cell
, vol.128
, pp. 707-719
-
-
Li, B.1
Carey, M.2
Workman, J.L.3
-
78
-
-
44949231368
-
Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling
-
doi: 10.1371/joumal.pone.0001487
-
Li, W., Bengtson, M. H., Ulbrich, A., Matsuda, A., Reddy, V. A., Orth, A., et al. (2008). Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling. PLoS ONE 3:el487. doi: 10.1371/joumal.pone.0001487
-
(2008)
PLoS ONE
, vol.3
-
-
Li, W.1
Bengtson, M.H.2
Ulbrich, A.3
Matsuda, A.4
Reddy, V.A.5
Orth, A.6
-
79
-
-
0027716843
-
Effects of histone acetylation, ubiquitination and variants on nucleosome stability
-
Li, W, Nagaraja, S., Delcuve, G. P., Hendzel, M. J., and Davie, J. R. (1993). Effects of histone acetylation, ubiquitination and variants on nucleosome stability. Biochem.J. 296(Pt 3), 737-744.
-
(1993)
Biochem.J.
, vol.296
, Issue.PART 3
, pp. 737-744
-
-
Li, W.1
Nagaraja, S.2
Delcuve, G.P.3
Hendzel, M.J.4
Davie, J.R.5
-
80
-
-
77953819028
-
SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PPl
-
Li, X., Lin, H. H., Chen, H., Xu, X., Shih, H. M., and Ann, D. K. (2010). SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PPl.Sri. Signal. 3, ra32.
-
(2010)
Sri. Signal.
, vol.3
-
-
Li, X.1
Lin, H.H.2
Chen, H.3
Xu, X.4
Shih, H.M.5
Ann, D.K.6
-
81
-
-
77957686732
-
The fate of irreparable DNA double-strand breaks and eroded telomeres at the nuclear periphery
-
Lisby, M., Teixeira, T., Gilson, E., and Geli, V. (2010). The fate of irreparable DNA double-strand breaks and eroded telomeres at the nuclear periphery. Nucleus 1,158-161.
-
(2010)
Nucleus
, vol.1
, pp. 158-161
-
-
Lisby, M.1
Teixeira, T.2
Gilson, E.3
Geli, V.4
-
82
-
-
84873631924
-
CHFRis important for the first wave of ubiquitination at DNA damage sites
-
Liu, C, Wu, J., Paudyal, S. C, You, Z., andYu.X. (2012). CHFRis important for the first wave of ubiquitination at DNA damage sites. Nucleic Acids Res. 41,1698-1710.
-
(2012)
Nucleic Acids Res
, vol.41
, pp. 1698-1710
-
-
Liu, C.1
Wu, J.2
Paudyal, S.C.3
You, Z.4
Yu, X.5
-
83
-
-
84871559319
-
The RING finger protein RNF8 ubiquitinates Nbsl to promote DNA double-strand break repair by homologous recombination
-
Lu, C. S., Truong, L. N., Aslanian, A., Shi, L. Z., Li, Y, Hwang, P. Y, et al. (2012). The RING finger protein RNF8 ubiquitinates Nbsl to promote DNA double-strand break repair by homologous recombination.J. Biol. Chem. 287, 43984-43994.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 43984-43994
-
-
Lu, C.S.1
Truong, L.N.2
Aslanian, A.3
Shi, L.Z.4
Li, Y.5
Hwang, P.Y.6
-
84
-
-
84861895067
-
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
-
Luijsterburg, M. S., Acs, K., Ackermann, L, Wiegant, W W, Bekker-Jensen, S., Larsen, D. H., et al. (2012). A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure. EMBO J. 31, 2511-2527.
-
(2012)
EMBO J
, vol.31
, pp. 2511-2527
-
-
Luijsterburg, M.S.1
Acs, K.2
Ackermann, L.3
Wiegant, W.W.4
Bekker-Jensen, S.5
Larsen, D.H.6
-
85
-
-
3342915628
-
Mdcl couples DNA double-strand break recognition by Nbsl with its H2AX-dependent chromatin retention
-
Lukas, C, Melander, E, Stucki, M., Falck, J., Bekker-Jensen, S., Goldberg, M., et al. (2004). Mdcl couples DNA double-strand break recognition by Nbsl with its H2AX-dependent chromatin retention. EMBO J. 23, 2674-2683.
-
(2004)
EMBO J
, vol.23
, pp. 2674-2683
-
-
Lukas, C.1
Melander, E.2
Stucki, M.3
Falck, J.4
Bekker-Jensen, S.5
Goldberg, M.6
-
86
-
-
84863846456
-
Sumoylation of MDC1 is important for proper DNA damage response
-
Luo, K., Zhang, H., Wang, L., Yuan, J., and Lou, Z. (2012). Sumoylation of MDC1 is important for proper DNA damage response. EMBO J. 31, 3008-3019.
-
(2012)
EMBO J
, vol.31
, pp. 3008-3019
-
-
Luo, K.1
Zhang, H.2
Wang, L.3
Yuan, J.4
Lou, Z.5
-
87
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand, N., Bekker-Jensen, S., Faustrup, H., Melander, E, Bartek, J., Lukas, C, et al. (2007). RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131, 887-900.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, E.4
Bartek, J.5
Lukas, C.6
-
88
-
-
84859895529
-
RNF8-and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
-
Mallette, F. A., Mattiroli, F., Cui, G., Young, L. C, Hendzel, M. J., Mer, G., et al. (2012). RNF8-and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J. 31, 1865-1878.
-
(2012)
EMBO J
, vol.31
, pp. 1865-1878
-
-
Mallette, F.A.1
Mattiroli, F.2
Cui, G.3
Young, L.C.4
Hendzel, M.J.5
Mer, G.6
-
89
-
-
70349944658
-
Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response
-
Marteijn, J. A., Bekker-Jensen, S., Mailand, N., Lans, H., Schwertman, P., Gourdin, A. M., et al. (2009). Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.J. Cell Biol. 186, 835-847.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 835-847
-
-
Marteijn, J.A.1
Bekker-Jensen, S.2
Mailand, N.3
Lans, H.4
Schwertman, P.5
Gourdin, A.M.6
-
90
-
-
84866388311
-
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
-
Mattiroli, F., Vissers, J. H., van Dijk, W. J., Ikpa, P., Citterio, E., Vermeulen, W., et al. (2012). RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling. Cell 150,1182-1195.
-
(2012)
Cell
, vol.150
, pp. 1182-1195
-
-
Mattiroli, F.1
Vissers, J.H.2
van Dijk, W.J.3
Ikpa, P.4
Citterio, E.5
Vermeulen, W.6
-
91
-
-
80455145246
-
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks
-
Meerang, M., Ritz, D., Paliwal, S., Garajova, Z., Bosshard, M., Mailand, N., et al. (2011). The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks. Nat. Cell Biol. 13, 1376-1382.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1376-1382
-
-
Meerang, M.1
Ritz, D.2
Paliwal, S.3
Garajova, Z.4
Bosshard, M.5
Mailand, N.6
-
92
-
-
84858142724
-
HECT and RING finger families of E3 ubiquitin ligases at a glance
-
Metzger, M. B., Hristova, V. A., and Weissman, A. M. (2012). HECT and RING finger families of E3 ubiquitin ligases at a glance.J. Cell. Sci. 125, 531-537.
-
(2012)
J. Cell. Sci.
, vol.125
, pp. 531-537
-
-
Metzger, M.B.1
Hristova, V.A.2
Weissman, A.M.3
-
93
-
-
72449163470
-
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
-
Morris, J. R., Boutell, C, Keppler, M., Densham, R., Weekes, D., Alamshah, A., et al. (2009). The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. Nature 462, 886-890.
-
(2009)
Nature
, vol.462
, pp. 886-890
-
-
Morris, J.R.1
Boutell, C.2
Keppler, M.3
Densham, R.4
Weekes, D.5
Alamshah, A.6
-
94
-
-
10944224673
-
INO80 and y-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair
-
Morrison, A. J., Highland, J., Krogan, N. J., Arbel-Eden, A., Green-blatt, J. E, Haber, J. E., et al. (2004). INO80 and y-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell 119, 767-775.
-
(2004)
Cell
, vol.119
, pp. 767-775
-
-
Morrison, A.J.1
Highland, J.2
Krogan, N.J.3
Arbel-Eden, A.4
Green-blatt, J.E.5
Haber, J.E.6
-
95
-
-
79951974992
-
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks
-
Moyal, L., Lerenthal, Y., Gana-Weisz, M., Mass, G., So, S., Wang, S. Y., et al. (2011). Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol. Cell 41, 529-542.
-
(2011)
Mol. Cell
, vol.41
, pp. 529-542
-
-
Moyal, L.1
Lerenthal, Y.2
Gana-Weisz, M.3
Mass, G.4
So, S.5
Wang, S.Y.6
-
96
-
-
79952538034
-
Nuclear organization in genome stability: SUMO connections
-
Nagai, S., Davoodi, N., and Gasser, S. M. (2011). Nuclear organization in genome stability: SUMO connections. Cell Res. 21, 474-485.
-
(2011)
Cell Res
, vol.21
, pp. 474-485
-
-
Nagai, S.1
Davoodi, N.2
Gasser, S.M.3
-
97
-
-
74949108644
-
The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks
-
Nakamura, A. J., Rao, V. A., Pommier, Y, and Bonner, W. M. (2010). The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks. Cell Cycle 9, 389-397.
-
(2010)
Cell Cycle
, vol.9
, pp. 389-397
-
-
Nakamura, A.J.1
Rao, V.A.2
Pommier, Y.3
Bonner, W.M.4
-
98
-
-
79951971464
-
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination
-
Nakamura, K., Kato, A., Kobayashi, J., Yanagihara, H., Sakamoto, S., Oliveira, D. V., et al. (2011). Regulation of homologous recombination by RNF20-dependent H2B ubiquitination. Mol. Cell 41, 515-528.
-
(2011)
Mol. Cell
, vol.41
, pp. 515-528
-
-
Nakamura, K.1
Kato, A.2
Kobayashi, J.3
Yanagihara, H.4
Sakamoto, S.5
Oliveira, D.V.6
-
99
-
-
75949122330
-
53BPl-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair
-
Noon, A. T., Shibata, A., Rief, N., Lobrich, M., Stewart, G. S., Jeggo, P. A., et al. (2010). 53BPl-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nat. Cell Biol. 12,177-184.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 177-184
-
-
Noon, A.T.1
Shibata, A.2
Rief, N.3
Lobrich, M.4
Stewart, G.S.5
Jeggo, P.A.6
-
100
-
-
73449092854
-
SUMO engages multiple corepressors to regulate chromatin structure and transcription
-
Ouyang, J., and Gill, G. (2009). SUMO engages multiple corepressors to regulate chromatin structure and transcription. Epigenetics 4, 440-444.
-
(2009)
Epigenetics
, vol.4
, pp. 440-444
-
-
Ouyang, J.1
Gill, G.2
-
101
-
-
65249150132
-
Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery
-
Oza, P., Jaspersen, S. L., Miele, A., Dekker, J., and Peterson, C. L. (2009). Mechanisms that regulate localization of a DNA double-strand break to the nuclear periphery. Genes Dev. 23,912-927.
-
(2009)
Genes Dev
, vol.23
, pp. 912-927
-
-
Oza, P.1
Jaspersen, S.L.2
Miele, A.3
Dekker, J.4
Peterson, C.L.5
-
102
-
-
80051494784
-
Monoubiquitination of H2AX protein regulates DNA damage response signaling
-
Pan, M. R., Peng, G., Hung, W. C, and Lin, S. Y (2011). Monoubiquitination of H2AX protein regulates DNA damage response signaling.J. Biol. Chem. 286, 28599-28607.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28599-28607
-
-
Pan, M.R.1
Peng, G.2
Hung, W.C.3
Lin, S.Y.4
-
103
-
-
63049101044
-
Regulatory ubiquitylation in response to DNA double-strand breaks
-
Panier, S., and Durocher, D. (2009). Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair (Amst) 8, 436-443.
-
(2009)
DNA Repair (Amst)
, vol.8
, pp. 436-443
-
-
Panier, S.1
Durocher, D.2
-
104
-
-
84864919890
-
Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks
-
Panier, S., Ichijima, Y, Fradet-Turcotte, A., Leung, C. C, Kaustov, L., Arrowsmith, C. H., et al. (2012). Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks. Mol. Cell 47, 383-395.
-
(2012)
Mol. Cell
, vol.47
, pp. 383-395
-
-
Panier, S.1
Ichijima, Y.2
Fradet-Turcotte, A.3
Leung, C.C.4
Kaustov, L.5
Arrowsmith, C.H.6
-
105
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull, T. T., Rogakou, E. P., Yamazaki, V., Kirchgessner, C. U., Gellert, M., and Bonner, W. M. (2000). A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10, 886-895.
-
(2000)
Curr. Biol.
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
106
-
-
79551665780
-
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
-
Pei, H., Zhang, L, Luo, K., Qin, Y, Chesi, M., Fei, E, et al. (2011). MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites. Nature 470, 124-128.
-
(2011)
Nature
, vol.470
, pp. 124-128
-
-
Pei, H.1
Zhang, L.2
Luo, K.3
Qin, Y.4
Chesi, M.5
Fei, E.6
-
107
-
-
43849093519
-
A SIM-ultaneous role for SUMO and ubiquitin
-
Perry, J. J., Tainer, J. A., and Boddy, M. N. (2008). A SIM-ultaneous role for SUMO and ubiquitin. Trends Biochem. Sci. 33, 201-208.
-
(2008)
Trends Biochem. Sci.
, vol.33
, pp. 201-208
-
-
Perry, J.J.1
Tainer, J.A.2
Boddy, M.N.3
-
108
-
-
0037059619
-
The nucleoporin RanBP2 has SUMO1 E3 ligase activity
-
Pichler, A., Gast, A., Seeler, J. S., Dejean, A., and Melchior, E (2002). The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell 108, 109-120.
-
(2002)
Cell
, vol.108
, pp. 109-120
-
-
Pichler, A.1
Gast, A.2
Seeler, J.S.3
Dejean, A.4
Melchior, E.5
-
109
-
-
78751682842
-
UMI, a novel RNF168 ubiquitin binding domain involved in the DNA damage signaling pathway
-
Pinato, S., Gatti, M., Scandiuzzi, C, Confalonieri, S., and Penengo, L. (2011). UMI, a novel RNF168 ubiquitin binding domain involved in the DNA damage signaling pathway. Mol. Cell. Biol. 31,118-126.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 118-126
-
-
Pinato, S.1
Gatti, M.2
Scandiuzzi, C.3
Confalonieri, S.4
Penengo, L.5
-
110
-
-
33144459648
-
The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation
-
Plans, V., Scheper, J., Soler, M., Loukili, N., Okano, Y, and Thomson, T. M. (2006). The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation.J. Cell. Biochem. 97, 572-582.
-
(2006)
J. Cell. Biochem.
, vol.97
, pp. 572-582
-
-
Plans, V.1
Scheper, J.2
Soler, M.3
Loukili, N.4
Okano, Y.5
Thomson, T.M.6
-
111
-
-
79952235291
-
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications
-
Polo, S. E., and Jackson, S. P. (2011). Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications. Genes Dev. 25, 409-433.
-
(2011)
Genes Dev
, vol.25
, pp. 409-433
-
-
Polo, S.E.1
Jackson, S.P.2
-
112
-
-
84861948252
-
Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
-
Poulsen, M., Lukas, C, Lukas, J., Bekker-Jensen, S., and Mailand, N. (2012). Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks.J. Cell Biol. 197, 189-199.
-
(2012)
J. Cell Biol.
, vol.197
, pp. 189-199
-
-
Poulsen, M.1
Lukas, C.2
Lukas, J.3
Bekker-Jensen, S.4
Mailand, N.5
-
113
-
-
34648840192
-
SUMO-targetedubiquitin ligases in genome stability
-
Prudden, J., Pebernard, S., Raffa, G., Slavin, D. A., Perry, J. J., Tainer, J. A., et al. (2007). SUMO-targetedubiquitin ligases in genome stability. EMBO J.26,4089-4101.
-
(2007)
EMBO J
, vol.26
, pp. 4089-4101
-
-
Prudden, J.1
Pebernard, S.2
Raffa, G.3
Slavin, D.A.4
Perry, J.J.5
Tainer, J.A.6
-
114
-
-
84869091913
-
Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair
-
Psakhye, I., and Jentsch, S. (2012). Protein group modification and synergy in the SUMO pathway as exemplified in DNA repair. Cell 151, 807-820.
-
(2012)
Cell
, vol.151
, pp. 807-820
-
-
Psakhye, I.1
Jentsch, S.2
-
115
-
-
84858735947
-
p97/VCP- and Lys48-linked polyubiquitination form a new signaling pathway in DNA damage response
-
Ramadan, K. (2012). p97/VCP- and Lys48-linked polyubiquitination form a new signaling pathway in DNA damage response. Cell Cycle 11, 1062-1069.
-
(2012)
Cell Cycle
, vol.11
, pp. 1062-1069
-
-
Ramadan, K.1
-
116
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., and Bonner, W. M. (1998). DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.J. Biol. Chem. 273, 5858-5868.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
117
-
-
67349132223
-
Physiological functions of the HECT family of ubiquitin ligases
-
Rotin, D., and Kumar, S. (2009). Physiological functions of the HECT family of ubiquitin ligases. Nat. Rev. Mol. Cell Biol. 10, 398-409.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 398-409
-
-
Rotin, D.1
Kumar, S.2
-
118
-
-
33745790132
-
Chromatin remodelling: the industrial revolution of DNA around histones
-
Saha, A., Wittmeyer, J., and Cairns, B. R. (2006). Chromatin remodelling: the industrial revolution of DNA around histones. Nat. Rev. Mol. Cell Biol. 7, 437-447.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 437-447
-
-
Saha, A.1
Wittmeyer, J.2
Cairns, B.R.3
-
119
-
-
0035118229
-
Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2a subunit of NuRD
-
Schultz, D. C, Friedman, J. R., and Rauscher, E J. III. (2001). Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2a subunit of NuRD. Genes Dev. 15,428-443.
-
(2001)
Genes Dev
, vol.15
, pp. 428-443
-
-
Schultz, D.C.1
Friedman, J.R.2
Rauscher III, E.J.3
-
120
-
-
62549140202
-
The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubcl3-dependent ubiquitination events at DNA double strand breaks
-
Shao, G., Lilli, D. R., Patterson-Fortin, J., Coleman, K. A., Morrissey, D. E., and Greenberg, R. A. (2009). The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubcl3-dependent ubiquitination events at DNA double strand breaks. Proc. Natl. Acad. Sci. U.S.A. 106, 3166-3171.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 3166-3171
-
-
Shao, G.1
Lilli, D.R.2
Patterson-Fortin, J.3
Coleman, K.A.4
Morrissey, D.E.5
Greenberg, R.A.6
-
121
-
-
5144219680
-
Identification of a SUMO-binding motif that recognizes SUMO-modifiedproteins
-
Song, J., Durrin, L. K., Wilkinson, T. A., Krontiris, T. G., and Chen, Y (2004). Identification of a SUMO-binding motif that recognizes SUMO-modifiedproteins. Proc. Natl. Acad. Sci. U.S.A. 101,14373-14378.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 14373-14378
-
-
Song, J.1
Durrin, L.K.2
Wilkinson, T.A.3
Krontiris, T.G.4
Chen, Y.5
-
122
-
-
33750379420
-
Polycomb silencers control cell fate, development and cancer
-
Sparmann, A., and van Lohuizen, M. (2006). Polycomb silencers control cell fate, development and cancer. Nat. Rev. Cancer 6, 846-856.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 846-856
-
-
Sparmann, A.1
van Lohuizen, M.2
-
123
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart, G. S., Panier, S., Townsend, K., Al-Hakim, A. K., Kolas, N. K., Miller, E. S., et al. (2009). The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 136,420-434.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
-
124
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
Stiff, T., O'Driscoll, M., Rief, N., Iwabuchi, K., Lobrich, M., and Jeggo, P. A. (2004). ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 64,2390-2396.
-
(2004)
Cancer Res
, vol.64
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
125
-
-
80052414082
-
Recruitment of proteins to DNA double-strand breaks: MDC1 directly recruits RAP80
-
Strauss, C, and Goldberg, M. (2011). Recruitment of proteins to DNA double-strand breaks: MDC1 directly recruits RAP80. Cell Cycle 10, 2850-2857.
-
(2011)
Cell Cycle
, vol.10
, pp. 2850-2857
-
-
Strauss, C.1
Goldberg, M.2
-
126
-
-
79960700729
-
MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner
-
Strauss, C, Halevy, T., Macarov, M., Argaman, L., and Goldberg, M. (2011). MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner. DNA Repair (Amst) 10, 806-814.
-
(2011)
DNA Repair (Amst)
, vol.10
, pp. 806-814
-
-
Strauss, C.1
Halevy, T.2
Macarov, M.3
Argaman, L.4
Goldberg, M.5
-
127
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki, M., Clapperton, J. A., Mohammad, D., Yaffe, M. B., Smerdon, S. J., and Jackson, S. P. (2005). MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123, 1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
128
-
-
43049093756
-
RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation
-
Tatham, M. H., Geoffroy, M. C, Shen, L., Plechanovova, A., Hattersley, N., Jaffray, E. G., et al. (2008). RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. Nat. Cell Biol. 10, 538-546.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 538-546
-
-
Tatham, M.H.1
Geoffroy, M.C.2
Shen, L.3
Plechanovova, A.4
Hattersley, N.5
Jaffray, E.G.6
-
129
-
-
0035929557
-
Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9
-
Tatham, M. H., Jaffray, E., Vaughan, O. A., Desterro, J. M., Botting, C. H., Naismith, J. H., et al. (2001). Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.J. Biol. Chem. 276, 35368-35374.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35368-35374
-
-
Tatham, M.H.1
Jaffray, E.2
Vaughan, O.A.3
Desterro, J.M.4
Botting, C.H.5
Naismith, J.H.6
-
130
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
Uziel, T., Lerenthal, Y, Moyal, L., Andegeko, Y, Mittelman, L., and Shiloh, Y (2003). Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 22, 5612-5621.
-
(2003)
EMBO J
, vol.22
, pp. 5612-5621
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
131
-
-
10944233962
-
Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair
-
van Attikum, H., Fritsch, O., Hohn, B., and Gasser, S. M. (2004). Recruitment of the INO80 complex by H2A phosphorylation links ATP-dependent chromatin remodeling with DNA double-strand break repair. Cell 119, 777-788.
-
(2004)
Cell
, vol.119
, pp. 777-788
-
-
van Attikum, H.1
Fritsch, O.2
Hohn, B.3
Gasser, S.M.4
-
132
-
-
65149084552
-
Crosstalk between histone modifications during the DNA damage response
-
van Attikum, H., and Gasser, S. M. (2009). Crosstalk between histone modifications during the DNA damage response. Trends Cell Biol. 19, 207-217.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 207-217
-
-
van Attikum, H.1
Gasser, S.M.2
-
133
-
-
0035875079
-
Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubcl3 heterodimer
-
Van Demark, A. P., Hofmann, R. M., Tsui, C, Pickart, C. M., and Wol-berger, C. (2001). Molecular insights into polyubiquitin chain assembly: crystal structure of the Mms2/Ubcl3 heterodimer. Cell 105, 711-720.
-
(2001)
Cell
, vol.105
, pp. 711-720
-
-
Van Demark, A.P.1
Hofmann, R.M.2
Tsui, C.3
Pickart, C.M.4
Wol-berger, C.5
-
134
-
-
0037295721
-
Modification withSUMO. A role in transcriptional regulation
-
Verger, A., Perdomo, J., and Crossley, M. (2003). Modification withSUMO. A role in transcriptional regulation. EMBORep. 4, 137-142.
-
(2003)
EMBORep
, vol.4
, pp. 137-142
-
-
Verger, A.1
Perdomo, J.2
Crossley, M.3
-
135
-
-
84873704658
-
RNF4 is required for DNA double-strand break repair in vivo
-
Vyas, R., Kumar, R., Clermont, E, Helfricht, A., Kalev, P., Sotiropoulou, P., et al. (2012). RNF4 is required for DNA double-strand break repair in vivo. Cell Death Differ. 20, 490-502.
-
(2012)
Cell Death Differ
, vol.20
, pp. 490-502
-
-
Vyas, R.1
Kumar, R.2
Clermont, E.3
Helfricht, A.4
Kalev, P.5
Sotiropoulou, P.6
-
136
-
-
84858124845
-
Generation and physiological roles of linear ubiquitin chains
-
doi: 10.1186/1741-7007-10-23
-
Walczak, H., Iwai, K., and Dikic, I. (2012). Generation and physiological roles of linear ubiquitin chains. BMC Biol. 10:23. doi: 10.1186/1741-7007-10-23
-
(2012)
BMC Biol
, vol.10
, pp. 23
-
-
Walczak, H.1
Iwai, K.2
Dikic, I.3
-
137
-
-
7244234099
-
Role of histone H2A ubiquitination in Polycomb silencing
-
Wang, H., Wang, L., Erdjument-Bromage, H., Vidal, M., Tempst, P., Jones, R. S., et al. (2004). Role of histone H2A ubiquitination in Polycomb silencing. Nature 431, 873-878.
-
(2004)
Nature
, vol.431
, pp. 873-878
-
-
Wang, H.1
Wang, L.2
Erdjument-Bromage, H.3
Vidal, M.4
Tempst, P.5
Jones, R.S.6
-
138
-
-
0035930537
-
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
-
Ward, I. M., and Chen, J. (2001). Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress.J. Biol. Chetn. 276,47759-47762.
-
(2001)
J. Biol. Chetn.
, vol.276
, pp. 47759-47762
-
-
Ward, I.M.1
Chen, J.2
-
139
-
-
0019319471
-
Histone 2A, a heteromorphous family of eight protein species
-
West, M. H., and Bonner, W. M. (1980). Histone 2A, a heteromorphous family of eight protein species. Biochemistry 19, 3238-3245.
-
(1980)
Biochemistry
, vol.19
, pp. 3238-3245
-
-
West, M.H.1
Bonner, W.M.2
-
140
-
-
80052238249
-
Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response
-
Wu, C. Y., Kang, H. Y., Yang, W. L, Wu, J., Jeong, Y. S., Wang, J., et al. (2011). Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response.J. Biol. Chem. 286,30806-30815.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 30806-30815
-
-
Wu, C.Y.1
Kang, H.Y.2
Yang, W.L.3
Wu, J.4
Jeong, Y.S.5
Wang, J.6
-
141
-
-
33845604556
-
DNA double-strand break repair: all's well that ends well
-
Wyman, C, and Kanaar, R. (2006). DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet. 40,363-383.
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 363-383
-
-
Wyman, C.1
Kanaar, R.2
-
142
-
-
11844297340
-
Histone H2B ubiquitylation is associated with elongating RNA polymerase II
-
Xiao, T., Kao, C. E, Krogan, N. J., Sun, Z. W, Greenblatt, J. E, Osley, M. A., et al. (2005). Histone H2B ubiquitylation is associated with elongating RNA polymerase II. Mol. Cell. Biol. 25,637-651.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 637-651
-
-
Xiao, T.1
Kao, C.E.2
Krogan, N.J.3
Sun, Z.W.4
Greenblatt, J.E.5
Osley, M.A.6
-
143
-
-
77957738825
-
The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair
-
Xu, Y, Sun, Y, Jiang, X., Ayrapetov, M. K., Moskwa, P., Yang, S., et al. (2010). The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair.J. Cell Biol. 191, 31-43.
-
(2010)
J. Cell Biol.
, vol.191
, pp. 31-43
-
-
Xu, Y.1
Sun, Y.2
Jiang, X.3
Ayrapetov, M.K.4
Moskwa, P.5
Yang, S.6
-
144
-
-
34548104404
-
RAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylation
-
Yan, J., Yang, X. P., Kim, Y S., Joo, J. H., and Jetten, A. M. (2007). RAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylation. Biochem. Biophys. Res. Cotntnun. 362, 132-138.
-
(2007)
Biochem. Biophys. Res. Cotntnun.
, vol.362
, pp. 132-138
-
-
Yan, J.1
Yang, X.P.2
Kim, Y.S.3
Joo, J.H.4
Jetten, A.M.5
-
145
-
-
84859047067
-
Promyelocytic leukemia nuclear bodies support a late step in DNA double-strand break repair by homologous recombination
-
Yeung, P. L., Denissova, N. G., Nasello, C, Hakhverdyan, Z., Chen, J. D., and Brenneman, M. A. (2012). Promyelocytic leukemia nuclear bodies support a late step in DNA double-strand break repair by homologous recombination. J. Cell. Biochem. 113, 1787-1799.
-
(2012)
J. Cell. Biochem.
, vol.113
, pp. 1787-1799
-
-
Yeung, P.L.1
Denissova, N.G.2
Nasello, C.3
Hakhverdyan, Z.4
Chen, J.D.5
Brenneman, M.A.6
-
146
-
-
84861784690
-
SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage
-
Yin, Y, Seifert, A., Chua, J. S., Maure, J. F., Golebiowski, F., and Hay, R. T. (2012). SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damage. Genes Dev. 26,1196-1208.
-
(2012)
Genes Dev
, vol.26
, pp. 1196-1208
-
-
Yin, Y.1
Seifert, A.2
Chua, J.S.3
Maure, J.F.4
Golebiowski, F.5
Hay, R.T.6
-
147
-
-
38149098408
-
Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation
-
Zhou, W., Zhu, P., Wang, J., Pascual, G., Ohgi, K. A., Lozach, J., et al. (2008). Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol. Cell 29, 69-80.
-
(2008)
Mol. Cell
, vol.29
, pp. 69-80
-
-
Zhou, W.1
Zhu, P.2
Wang, J.3
Pascual, G.4
Ohgi, K.A.5
Lozach, J.6
-
148
-
-
27944454433
-
Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation
-
Zhu, B., Zheng, Y., Pham, A. D., Mandal, S. S., Erdjument-Bromage, H., Tempst, P., et al. (2005). Monoubiq-uitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Mol. Cell 20, 601-611.
-
(2005)
Mol. Cell
, vol.20
, pp. 601-611
-
-
Zhu, B.1
Zheng, Y.2
Pham, A.D.3
Mandal, S.S.4
Erdjument-Bromage, H.5
Tempst, P.6
-
149
-
-
84873488846
-
53BP1 regulates DSB repair using Rifl to control 5; end resection
-
Zimmermann, M., Lottersberger, F., Buonomo, S. B., Sfeir, A., and de Lange, T. (2013). 53BP1 regulates DSB repair using Rifl to control 5; end resection. Science 339, 700-704.
-
(2013)
Science
, vol.339
, pp. 700-704
-
-
Zimmermann, M.1
Lottersberger, F.2
Buonomo, S.B.3
Sfeir, A.4
de Lange, T.5
-
150
-
-
33746601439
-
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM-and KAP-1 dependent pathway
-
Ziv, Y, Bielopolski, D., Galanty, Y, Lukas, C, Taya, Y, Schultz, D. C, et al. (2006). Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM-and KAP-1 dependent pathway. Nat. Cell Biol. 8, 870-876.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 870-876
-
-
Ziv, Y.1
Bielopolski, D.2
Galanty, Y.3
Lukas, C.4
Taya, Y.5
Schultz, D.C.6
|