-
1
-
-
0037178748
-
Interfaces between the detection, signaling, and repair of DNA damage
-
Rouse,J. and Jackson,S.P. (2002) Interfaces between the detection, signaling, and repair of DNA damage. Science, 297, 547-551.
-
(2002)
Science
, vol.297
, pp. 547-551
-
-
Rouse, J.1
Jackson, S.P.2
-
2
-
-
36749022214
-
The DNA damage response: Ten years after
-
Harper,J.W. and Elledge,S.J. (2007) The DNA damage response: ten years after. Mol. Cell, 28, 739-745.
-
(2007)
Mol. Cell
, vol.28
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
3
-
-
80052697814
-
The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks
-
Bekker-Jensen,S. and Mailand,N. (2011) The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks. FEBS Lett., 585, 2914-2919.
-
(2011)
FEBS Lett.
, vol.585
, pp. 2914-2919
-
-
Bekker-Jensen, S.1
Mailand, N.2
-
4
-
-
63049101044
-
Regulatory ubiquitylation in response to DNA double-strand breaks
-
Panier,S. and Durocher,D. (2009) Regulatory ubiquitylation in response to DNA double-strand breaks. DNA Repair, 8, 436-443.
-
(2009)
DNA Repair
, vol.8
, pp. 436-443
-
-
Panier, S.1
Durocher, D.2
-
5
-
-
78649492271
-
The ubiquitous role of ubiquitin in the DNA damage response
-
Al-Hakim,A., Escribano-Diaz,C., Landry,M.C., O'Donnell,L., Panier,S., Szilard,R.K. and Durocher,D. (2010) The ubiquitous role of ubiquitin in the DNA damage response. DNA Repair, 9, 1229-1240.
-
(2010)
DNA Repair
, vol.9
, pp. 1229-1240
-
-
Szilard, R.K.1
Durocher, D.2
-
6
-
-
75549087964
-
The ubiquitin landscape at DNA double-strand breaks
-
Messick,T.E. and Greenberg,R.A. (2009) The ubiquitin landscape at DNA double-strand breaks. J. Cell Biol., 187, 319-326.
-
(2009)
J. Cell Biol.
, vol.187
, pp. 319-326
-
-
Messick, T.E.1
Greenberg, R.A.2
-
7
-
-
79955457638
-
RNF8-dependent histone ubiquitination during DNA damage response and spermatogenesis
-
Ma,T., Keller,J.A. and Yu,X. (2011) RNF8-dependent histone ubiquitination during DNA damage response and spermatogenesis. Acta Biochim. Biophys. Sin., 43, 339-345.
-
(2011)
Acta Biochim. Biophys. Sin.
, vol.43
, pp. 339-345
-
-
Keller, J.A.1
Yu, X.2
-
8
-
-
20444391346
-
Chromatin in need of a fix: Phosphorylation of H2AX connects chromatin to DNA repair
-
Thiriet,C. and Hayes,J.J. (2005) Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair. Mol. Cell, 18, 617-622.
-
(2005)
Mol. Cell
, vol.18
, pp. 617-622
-
-
Thiriet, C.1
Hayes, J.J.2
-
9
-
-
1942437991
-
SUMO: A regulator of gene expression and genome integrity
-
Mu? ller,S., Ledl,A. and Schmidt,D. (2004) SUMO: a regulator of gene expression and genome integrity. Oncogene, 23, 1998-2008.
-
(2004)
Oncogene
, vol.23
, pp. 1998-2008
-
-
Muller, S.1
Ledl, A.2
Schmidt, D.3
-
10
-
-
0028865245
-
Post-translational modification of poly (ADP-ribose) polymerase induced by DNA strand breaks
-
Lindahl,T., Satoh,M.S., Poirier,G.G. and Klungland,A. (1995) Post-translational modification of poly (ADP-ribose) polymerase induced by DNA strand breaks. Trends Biochem. Sci., 20, 405-411.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 405-411
-
-
Poirier, G.G.1
Klungland, A.2
-
11
-
-
80052765356
-
SUMOylation and de-SUMOylation in response to DNA damage
-
Dou,H., Huang,C., Van Nguyen,T., Lu,L.S. and Yeh,E.T.H. (2011) SUMOylation and de-SUMOylation in response to DNA damage. FEBS Lett., 585, 2891-2896.
-
(2011)
FEBS Lett.
, vol.585
, pp. 2891-2896
-
-
Van Nguyen, T.1
Lu, L.S.2
Yeh, E.T.H.3
-
12
-
-
33846087335
-
SUMOylation code in cancer development and metastasis
-
Kim,K.I. and Baek,S.H. (2006) SUMOylation code in cancer development and metastasis. Mol. Cells, 22, 247-253.
-
(2006)
Mol. Cells
, vol.22
, pp. 247-253
-
-
Kim, K.I.1
Baek, S.H.2
-
13
-
-
34147095806
-
Protein methylation and DNA repair
-
Lake,A.N. and Bedford,M.T. (2007) Protein methylation and DNA repair. Mutat. Res., 618, 91-101.
-
(2007)
Mutat. Res.
, vol.618
, pp. 91-101
-
-
Lake, A.N.1
Bedford, M.T.2
-
14
-
-
28444456705
-
The histone code at DNA breaks: A guide to repair?
-
Van Attikum,H. and Gasser,S.M. (2005) The histone code at DNA breaks: a guide to repair? Nat. Rev. Mol. Cell Biol., 6, 757-765.
-
(2005)
Nat Rev. Mol. Cell Biol.
, vol.6
, pp. 757-765
-
-
Van Attikum, H.1
Gasser, S.M.2
-
15
-
-
33644852073
-
Histone post-translational modifications and the response to DNA double-strand breaks
-
Wurtele,H. and Verreault,A. (2006) Histone post-translational modifications and the response to DNA double-strand breaks. Curr. Opin. Cell Biol., 18, 137-144.
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 137-144
-
-
Wurtele, H.1
Verreault, A.2
-
16
-
-
77952866393
-
More modifiers move on DNA damage
-
Morris,J.R. (2010) More modifiers move on DNA damage. Cancer Res., 70, 3861-3863.
-
(2010)
Cancer Res.
, vol.70
, pp. 3861-3863
-
-
Morris, J.R.1
-
17
-
-
2342527027
-
DNA damage checkpoint and repair centers
-
Lisby,M. and Rothstein,R. (2004) DNA damage checkpoint and repair centers. Curr. Opin. Cell Biol., 16, 328-334.
-
(2004)
Curr. Opin. Cell Biol.
, vol.16
, pp. 328-334
-
-
Lisby, M.1
Rothstein, R.2
-
18
-
-
33144459648
-
The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation
-
Plans,V., Scheper,J., Soler,M., Loukili,N., Okano,Y. and Thomson,T.M. (2006) The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation. J. Cell. Biochem., 97, 572-582.
-
(2006)
J. Cell. Biochem.
, vol.97
, pp. 572-582
-
-
Okano, Y.1
Thomson, T.M.2
-
19
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen,M.S., Grant,R., Manke,I., Minn,K., Yu,X., Yaffe,M.B. and Chen,J. (2007) RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell, 131, 901-914.
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Yaffe, M.B.1
Chen, J.2
-
20
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
Kolas,N.K., Chapman,J.R., Nakada,S., Ylanko,J., Chahwan,R., Sweeney,F.D., Panier,S., Mendez,M., Wildenhain,J., Thomson,T.M. et al. (2007) Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science, 318, 1637-1640.
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Thomson, T.M.1
-
21
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand,N., Bekker-Jensen,S., Faustrup,H., Melander,F., Bartek,J., Lukas,C. and Lukas,J. (2007) RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell, 131, 887-900.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Lukas, C.1
Lukas, J.2
-
22
-
-
36749025467
-
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
-
Wang,B. and Elledge,S.J. (2007) Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage. Proc. Natl Acad. Sci. USA, 104, 20759-20763.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 20759-20763
-
-
Wang, B.1
Elledge, S.J.2
-
23
-
-
70349944658
-
Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response
-
Marteijn,J.A., Bekker-Jensen,S., Mailand,N., Lans,H., Schwertman,P., Gourdin,A.M., Dantuma,N.P., Lukas,J. and Vermeulen,W. (2009) Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response. J. Cell Biol., 186, 835-847.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 835-847
-
-
Lukas, J.1
Vermeulen, W.2
-
24
-
-
59249095962
-
Histone ubiquitination associates with BRCA1-dependent DNA damage response
-
Wu,J., Huen,M.S., Lu,L.Y., Ye,L., Dou,Y., Ljungman,M., Chen,J. and Yu,X. (2009) Histone ubiquitination associates with BRCA1-dependent DNA damage response. Mol. Cell. Biol., 29, 849-860.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 849-860
-
-
Chen, J.1
Yu, X.2
-
25
-
-
33847413700
-
A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination
-
Zhao,G.Y., Sonoda,E., Barber,L.J., Oka,H., Murakawa,Y., Yamada,K., Ikura,T., Wang,X., Kobayashi,M. and Yamamoto,K. (2007) A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Mol. Cell, 25, 663-675.
-
(2007)
Mol. Cell
, vol.25
, pp. 663-675
-
-
Kobayashi, M.1
Yamamoto, K.2
-
26
-
-
46649116785
-
RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage
-
Sakasai,R. and Tibbetts,R. (2008) RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage. J. Biol. Chem., 283, 13549-13555.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13549-13555
-
-
Sakasai, R.1
Tibbetts, R.2
-
27
-
-
84862777619
-
The E3 ligase RNF8 regulates KU80 removal and NHEJ repair
-
Feng,L. and Chen,J. (2012) The E3 ligase RNF8 regulates KU80 removal and NHEJ repair. Nat. Struct. Mol. Biol., 19, 201-206.
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 201-206
-
-
Feng, L.1
Chen, J.2
-
28
-
-
84862986431
-
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
-
Bekker-Jensen,S., Rendtlew Danielsen,J., Fugger,K., Gromova,I., Nerstedt,A., Lukas,C., Bartek,J., Lukas,J. and Mailand,N. (2010) HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes. Nat. Cell Biol., 12, 80-86.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 80-86
-
-
Danielsen, J.1
Fugger, K.2
Gromovai Nerstedt, A.3
Lukas, C.4
Bartek, J.5
Lukas, J.6
Mailand, N.7
-
29
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart,G.S., Panier,S., Townsend,K., Al-Hakim,A.K., Kolas,N.K., Miller,E.S., Nakada,S., Ylanko,J., Olivarius,S., Mendez,M. et al. (2009) The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell, 136, 420-434.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Mendez, M.1
-
30
-
-
66849138419
-
Solving the RIDDLE of 53BP1 recruitment to sites of damage
-
Stewart,G.S. (2009) Solving the RIDDLE of 53BP1 recruitment to sites of damage. Cell Cycle, 8, 1532-1538.
-
(2009)
Cell Cycle
, vol.8
, pp. 1532-1538
-
-
Stewart, G.S.1
-
31
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil,C., Mailand,N., Bekker-Jensen,S., Menard,P., Larsen,D.H., Pepperkok,R., Ellenberg,J., Panier,S., Durocher,D., Bartek,J. et al. (2009) RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell, 136, 435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Bartek, J.1
-
32
-
-
77950422142
-
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
-
Kang,T.H., Lindsey-Boltz,L.A., Reardon,J.T. and Sancar,A. (2010) Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase. Proc. Natl Acad. Sci. USA, 107, 4890-4895.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 4890-4895
-
-
Reardon, J.T.1
Sancar, A.2
-
33
-
-
77955347759
-
HERC2 is an E3 ligase that targets BRCA1 for degradation
-
Wu,W., Sato,K., Koike,A., Nishikawa,H., Koizumi,H., Venkitaraman,A.R. and Ohta,T. (2010) HERC2 is an E3 ligase that targets BRCA1 for degradation. Cancer Res., 70, 6384-6392.
-
(2010)
Cancer Res.
, vol.70
, pp. 6384-6392
-
-
Venkitaraman, A.R.1
Ohta, T.2
-
34
-
-
0034600851
-
Two RING finger proteins mediate cooperation between ubiquitin- conjugating enzymes in DNA repair
-
Ulrich,H.D. and Jentsch,S. (2000) Two RING finger proteins mediate cooperation between ubiquitin-conjugating enzymes in DNA repair. EMBO J., 19, 3388-3397.
-
(2000)
EMBO J.
, vol.19
, pp. 3388-3397
-
-
Ulrich, H.D.1
Jentsch, S.2
-
35
-
-
0030800865
-
Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating DNA binding, and ATP hydrolytic activities
-
Bailly,V., Lauder,S., Prakash,S. and Prakash,L. (1997) Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities. J. Biol. Chem., 272, 23360-23365.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23360-23365
-
-
Prakash, S.1
Prakash, L.2
-
36
-
-
0037068455
-
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
-
Hoege,C., Pfander,B., Moldovan,G.L., Pyrowolakis,G. and Jentsch,S. (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature, 419, 135-141.
-
(2002)
Nature
, vol.419
, pp. 135-141
-
-
Pyrowolakis, G.1
Jentsch, S.2
-
37
-
-
55849111846
-
PCNA is ubiquitinated by RNF8
-
Zhang,S., Chea,J., Meng,X., Zhou,Y., Lee,E.Y. and Lee,M.Y. (2008) PCNA is ubiquitinated by RNF8. Cell Cycle, 7, 3399-3404.
-
(2008)
Cell Cycle
, vol.7
, pp. 3399-3404
-
-
Lee, E.Y.1
Lee, M.Y.2
-
38
-
-
67349168142
-
RAD18 transmits DNA damage signalling to elicit homologous recombination repair
-
Huang,J., Huen,M.S., Kim,H., Leung,C.C., Glover,J.N., Yu,X. and Chen,J. (2009) RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat. Cell Biol., 11, 592-603.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 592-603
-
-
Chen, J.1
-
39
-
-
79960034248
-
Chfr and RNF8 synergistically regulate ATM activation
-
Wu,J., Chen,Y., Lu,L.Y., Wu,Y., Paulsen,M.T., Ljungman,M., Ferguson,D.O. and Yu,X. (2011) Chfr and RNF8 synergistically regulate ATM activation. Nat. Struct. Mol. Biol., 18, 761-768.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 761-768
-
-
Ferguson, D.O.1
Yu, X.2
-
40
-
-
0034721154
-
Chfr defines a mitotic stress checkpoint that delays entry into metaphase
-
Scolnick,D.M. and Halazonetis,T.D. (2000) Chfr defines a mitotic stress checkpoint that delays entry into metaphase. Nature, 406, 430-435.
-
(2000)
Nature
, vol.406
, pp. 430-435
-
-
Scolnick, D.M.1
Halazonetis, T.D.2
-
41
-
-
52649105473
-
Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly
-
Huen,M.S., Huang,J., Yuan,J., Yamamoto,M., Akira,S., Ashley,C., Xiao,W. and Chen,J. (2008) Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly. Mol. Cell. Biol., 28, 6104-6112.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 6104-6112
-
-
Xiao, W.1
Chen, J.2
-
42
-
-
0242551691
-
The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains
-
Bothos,J., Summers,M.K., Venere,M., Scolnick,D.M. and Halazonetis,T.D. (2003) The Chfr mitotic checkpoint protein functions with Ubc13-Mms2 to form Lys63-linked polyubiquitin chains. Oncogene, 22, 7101-7107.
-
(2003)
Oncogene
, vol.22
, pp. 7101-7107
-
-
Scolnick, D.M.1
Halazonetis, T.D.2
-
43
-
-
85047695475
-
Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers
-
Mizuno,K., Osada,H., Konishi,H., Tatematsu,Y., Yatabe,Y., Mitsudomi,T., Fujii,Y. and Takahashi,T. (2002) Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers. Oncogene, 21, 2328-2333.
-
(2002)
Oncogene
, vol.21
, pp. 2328-2333
-
-
Fujii, Y.1
Takahashi, T.2
-
44
-
-
0036799843
-
Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer
-
Shibata,Y., Haruki,N., Kuwabara,Y., Ishiguro,H., Shinoda,N., Sato,A., Kimura,M., Koyama,H., Toyama,T., Nishiwaki,T. et al. (2002) Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer. Carcinogenesis, 23, 1695-1699.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1695-1699
-
-
Nishiwaki, T.1
-
45
-
-
0037275750
-
Frequent hypermethylation of the 50 CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer
-
Corn,P.G., Summers,M.K., Fogt,F., Virmani,A.K., Gazdar,A.F., Halazonetis,T.D. and El-Deiry,W.S. (2003) Frequent hypermethylation of the 50 CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer. Carcinogenesis, 24, 47-51.
-
(2003)
Carcinogenesis
, vol.24
, pp. 47-51
-
-
Halazonetis, T.D.1
El-Deiry, W.S.2
-
46
-
-
0242442559
-
Inactivating mutations targeting the chfr mitotic checkpoint gene in human lung cancer
-
Mariatos,G., Bothos,J., Zacharatos,P., Summers,M.K., Scolnick,D.M., Kittas,C., Halazonetis,T.D. and Gorgoulis,V.G. (2003) Inactivating mutations targeting the chfr mitotic checkpoint gene in human lung cancer. Cancer Res., 63, 7185-7189.
-
(2003)
Cancer Res.
, vol.63
, pp. 7185-7189
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
-
47
-
-
0037934421
-
Epigenetic inactivation of CHFR in human tumors
-
Toyota,M., Sasaki,Y., Satoh,A., Ogi,K., Kikuchi,T., Suzuki,H., Mita,H., Tanaka,N., Itoh,F. and Issa,J.P.J. (2003) Epigenetic inactivation of CHFR in human tumors. Proc. Natl Acad. Sci. USA, 100, 7818-7823.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 7818-7823
-
-
Itoh, F.1
Issa, J.P.J.2
-
48
-
-
38049064044
-
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins
-
Ahel,I., Ahel,D., Matsusaka,T., Clark,A.J., Pines,J., Boulton,S.J. and West,S.C. (2008) Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins. Nature, 451, 81-85.
-
(2008)
Nature
, vol.451
, pp. 81-85
-
-
Boulton, S.J.1
West, S.C.2
-
49
-
-
78649874455
-
Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING Domains (CHFR
-
Oberoi,J., Richards,M.W., Crumpler,S., Brown,N., Blagg,J. and Bayliss,R. (2010) Structural basis of poly(ADP-ribose) recognition by the multizinc binding domain of checkpoint with forkhead-associated and RING Domains (CHFR). J. Biol. Chem., 285, 39348-39358.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 39348-39358
-
-
Blagg, J.1
Bayliss, R.2
-
50
-
-
75649100908
-
Solution structure of a zinc-finger domain that binds to poly-ADP-ribose
-
Isogai,S., Kanno,S., Ariyoshi,M., Tochio,H., Ito,Y., Yasui,A. and Shirakawa,M. (2010) Solution structure of a zinc-finger domain that binds to poly-ADP-ribose. Genes Cells, 15, 101-110.
-
(2010)
Genes Cells
, vol.15
, pp. 101-110
-
-
Yasui, A.1
Shirakawa, M.2
-
51
-
-
20144386737
-
Chfr is required for tumor suppression and Aurora A regulation
-
Yu,X., Minter-Dykhouse,K., Malureanu,L., Zhao,W.M., Zhang,D., Merkle,C.J., Ward,I.M., Saya,H., Fang,G. and Van Deursen,J. (2005) Chfr is required for tumor suppression and Aurora A regulation. Nat. Genet., 37, 401-406.
-
(2005)
Nat. Genet.
, vol.37
, pp. 401-406
-
-
Fang, G.1
Van Deursen, J.2
-
52
-
-
0019876860
-
Poly (ADP-ribose) synthetase a main acceptor of poly (ADP-ribose) in isolated nuclei
-
Ogata,N., Ueda,K., Kawaichi,M. and Hayaishi,O. (1981) Poly (ADP-ribose) synthetase, a main acceptor of poly (ADP-ribose) in isolated nuclei. J. Biol. Chem., 256, 4135-4137.
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 4135-4137
-
-
Kawaichi, M.1
Hayaishi, O.2
-
53
-
-
34447548569
-
Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly (ADP-ribose)-dependent pathway in the early response to DNA-damaging agents
-
Haince,J.F., Kozlov,S., Dawson,V.L., Dawson,T.M., Hendzel,M.J., Lavin,M.F. and Poirier,G.G. (2007) Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly (ADP-ribose)-dependent pathway in the early response to DNA-damaging agents. J. Biol. Chem., 282, 16441-16453.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16441-16453
-
-
Lavin, M.F.1
Poirier, G.G.2
-
54
-
-
81155162490
-
The PARP inhibitor PJ34 causes a PARP1-independent, p21 dependent mitotic arrest
-
Madison,D.L., Stauffer,D. and Lundblad,J.R. (2011) The PARP inhibitor PJ34 causes a PARP1-independent, p21 dependent mitotic arrest. DNA Repair, 10, 1003-1013.
-
(2011)
DNA Repair
, vol.10
, pp. 1003-1013
-
-
Stauffer, D.1
Lundblad, J.R.2
-
55
-
-
77950023283
-
PARP inhibition: PARP1 and beyond
-
Rouleau,M., Patel,A., Hendzel,M.J., Kaufmann,S.H. and Poirier,G.G. (2010) PARP inhibition: PARP1 and beyond. Nat. Rev. Cancer, 10, 293-301.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 293-301
-
-
Kaufmann, S.H.1
Poirier, G.G.2
-
56
-
-
68949178566
-
Radiation-induced mitotic catastrophe in PARG-deficient cells
-
Amé ,J.C., Fouquerel,E., Gauthier,L.R., Biard,D., Boussin,F.D., Dantzer,F., de Murcia,G. and Schreiber,V. (2009) Radiation-induced mitotic catastrophe in PARG-deficient cells. J. Cell Sci., 122, 1990-2002.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 1990-2002
-
-
Amé, J.C.1
Fouquerel, E.2
Gauthier, L.R.3
Biard, D.4
Boussin, F.D.5
Dantzer, F.6
De Murcia, G.7
Schreiber, V.8
-
57
-
-
3543031621
-
Depletion of the 110-kilodalton isoform of poly (ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice
-
Cortes,U., Tong,W.M., Coyle,D.L., Meyer-Ficca,M.L., Meyer,R.G., Petrilli,V., Herceg,Z., Jacobson,E.L., Jacobson,M.K. and Wang,Z.Q. (2004) Depletion of the 110-kilodalton isoform of poly (ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice. Mol. Cell. Biol., 24, 7163-7178.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7163-7178
-
-
Jacobson, M.K.1
Wang, Z.Q.2
-
58
-
-
19944418213
-
Failure to degrade poly (ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality
-
Koh,D.W., Lawler,A.M., Poitras,M.F., Sasaki,M., Wattler,S., Nehls,M.C., Sto? ger,T., Poirier,G.G., Dawson,V.L. and Dawson,T.M. (2004) Failure to degrade poly (ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality. Proc. Natl Acad. Sci. USA, 101, 17699-17704.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 17699-17704
-
-
Koh, D.W.1
Lawler, A.M.2
Poitras, M.F.3
Sasaki, M.4
Wattler, S.5
Nehls, M.C.6
Stoger, T.7
Poirier, G.G.8
Dawson, V.L.9
Dawson, T.M.10
-
59
-
-
77956043225
-
Enhanced DNA accessibility and increased DNA damage induced by the absence of poly (ADP-ribose) hydrolysis
-
Zhou,Y., Feng,X. and Koh,D.W. (2010) Enhanced DNA accessibility and increased DNA damage induced by the absence of poly (ADP-ribose) hydrolysis. Biochemistry, 49, 7360-7366.
-
(2010)
Biochemistry
, vol.49
, pp. 7360-7366
-
-
Feng, X.1
Koh, D.W.2
-
60
-
-
79953717442
-
Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly (ADP-ribose) glycohydrolase
-
Zhou,Y., Feng,X. and Koh,D.W. (2011) Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly (ADP-ribose) glycohydrolase. Biochemistry, 50, 2850-2859.
-
(2011)
Biochemistry
, vol.50
, pp. 2850-2859
-
-
Feng, X.1
Koh, D.W.2
-
61
-
-
0024406764
-
The effect of poly (ADP-ribosyl) ation on native and H1-depleted chromatin A role of poly (ADP-ribosyl) ation on core nucleosome structure
-
Huletsky,A., De Murcia,G., Muller,S., Hengartner,M., Menard,L., Lamarre,D. and Poirier,G. (1989) The effect of poly (ADP-ribosyl) ation on native and H1-depleted chromatin. A role of poly (ADP-ribosyl) ation on core nucleosome structure. J. Biol. Chem., 264, 8878-8886.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 8878-8886
-
-
De Murcia, G.1
Muller, S.2
Hengartner, M.3
Menard, L.4
Lamarre, D.5
Poirier, G.6
-
62
-
-
0033198919
-
Poly (ADP-ribosyl) ation reactions in the regulation of nuclear functions
-
D'Amours,D., Desnoyers,S., D'Silva,I. and Poirier,G.G. (1999) Poly (ADP-ribosyl) ation reactions in the regulation of nuclear functions. Biochem. J., 342, 249-268.
-
(1999)
Biochem. J.
, vol.342
, pp. 249-268
-
-
D'Silva, I.1
Poirier, G.G.2
-
63
-
-
26444569913
-
Inhibition of Aurora-B kinase activity by poly (ADP-ribosyl) ation in response to DNA damage
-
Monaco,L., Kolthur-Seetharam,U., Loury,R., Murcia,J.M., De Murcia,G. and Sassone-Corsi,P. (2005) Inhibition of Aurora-B kinase activity by poly (ADP-ribosyl) ation in response to DNA damage. Proc. Natl Acad. Sci. USA, 102, 14244-14248.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 14244-14248
-
-
De Murcia, G.1
Sassone-Corsi, P.2
-
64
-
-
2942703171
-
Poly (ADP-ribosyl) ation of polynucleosomes causes relaxation of chromatin structure
-
Poirier,G.G., De Murcia,G., Jongstra-Bilen,J., Niedergang,C. and Mandel,P. (1982) Poly (ADP-ribosyl) ation of polynucleosomes causes relaxation of chromatin structure. Proc. Natl Acad. Sci. USA, 79, 3423-3427.
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 3423-3427
-
-
De Murcia, G.1
Jongstra-Bilen, J.2
Niedergang, C.3
Mandel, P.4
-
65
-
-
0031844311
-
XRCC1 is specifically associated with poly (ADP-ribose) polymerase and negatively regulates its activity following DNA damage
-
Masson,M., Niedergang,C., Schreiber,V., Muller,S., Menissier-de Murcia,J. and de Murcia,G. (1998) XRCC1 is specifically associated with poly (ADP-ribose) polymerase and negatively regulates its activity following DNA damage. Mol. Cell. Biol., 18, 3563-3571.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3563-3571
-
-
Menissier-De Murcia, J.1
De Murcia, G.2
-
66
-
-
0032486256
-
Stimulation of the DNA-dependent protein kinase by poly (ADP-ribose) polymerase
-
Ruscetti,T., Lehnert,B.E., Halbrook,J., Le Trong,H., Hoekstra,M.F., Chen,D.J. and Peterson,S.R. (1998) Stimulation of the DNA-dependent protein kinase by poly (ADP-ribose) polymerase. J. Biol. Chem., 273, 14461-14467.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14461-14467
-
-
Le Trong, H.1
Hoekstra, M.F.2
Chen, D.J.3
Peterson, S.R.4
-
67
-
-
38049007502
-
Feedback-regulated poly (ADP-ribosyl) ation by PARP-1 is required for rapid response to DNA damage in living cells
-
Mortusewicz,O., Amé ,J.C., Schreiber,V. and Leonhardt,H. (2007) Feedback-regulated poly (ADP-ribosyl) ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Res., 35, 7665-7675.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7665-7675
-
-
Amé, J.C.1
Schreiber, V.2
Leonhardt, H.3
-
68
-
-
38149057387
-
PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites
-
Haince,J.F., McDonald,D., Rodrigue,A., Déry,U., Masson,J.Y., Hendzel,M.J. and Poirier,G.G. (2008) PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites. J. Biol. Chem., 283, 1197-1208.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1197-1208
-
-
Hendzel, M.J.1
Poirier, G.G.2
-
69
-
-
69949123856
-
Poly (ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1
-
Ahel,D., Horejsí,Z., Wiechens,N., Polo,S.E., Garcia-Wilson,E., Ahel,I., Flynn,H., Skehel,M., West,S.C. and Jackson,S.P. (2009) Poly (ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science, 325, 1240-1243.
-
(2009)
Science
, vol.325
, pp. 1240-1243
-
-
Ahel, D.1
Horejsí, Z.2
Wiechens, N.3
Polo, S.E.4
Garcia-Wilson, E.5
Ahel, I.6
Flynn, H.7
Skehel, M.8
West, S.C.9
Jackson, S.P.10
-
70
-
-
69949133036
-
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
-
Timinszky,G., Till,S., Hassa,P.O., Hothorn,M., Kustatscher,G., Nijmeijer,B., Colombelli,J., Altmeyer,M., Stelzer,E.H.K. and Scheffzek,K. (2009) A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat. Struct. Mol. Biol., 16, 923-929.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 923-929
-
-
Stelzer, E.H.K.1
Scheffzek, K.2
-
71
-
-
80053555789
-
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance
-
Lukas,J., Lukas,C. and Bartek,J. (2011) More than just a focus: the chromatin response to DNA damage and its role in genome integrity maintenance. Nat. Cell Biol., 13, 1161-1169.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1161-1169
-
-
Lukas, C.1
Bartek, J.2
-
72
-
-
69549083315
-
Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler
-
Gottschalk,A.J., Timinszky,G., Kong,S.E., Jin,J., Cai,Y., Swanson,S.K., Washburn,M.P., Florens,L., Ladurner,A.G., Conaway,J.W. et al. (2009) Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler. Proc. Natl Acad. Sci. USA, 106, 13770-13774.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 13770-13774
-
-
Conaway, J.W.1
-
73
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
-
Leist,M., Single,B., Castoldi,A.F., Ku? hnle,S. and Nicotera,P. (1997) Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med., 185, 1481-1486.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1481-1486
-
-
Leist, M.1
Single, B.2
Castoldi, A.F.3
Kuhnle, S.4
Nicotera, P.5
-
74
-
-
0030915587
-
Intracellular ATP levels determine cell death fate by apoptosis or necrosis
-
Eguchi,Y., Shimizu,S. and Tsujimoto,Y. (1997) Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res., 57, 1835-1840.
-
(1997)
Cancer Res.
, vol.57
, pp. 1835-1840
-
-
Shimizu, S.1
Tsujimoto, Y.2
-
75
-
-
0033598713
-
Poly (ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
-
Ha,H.C. and Snyder,S.H. (1999) Poly (ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion. Proc. Natl Acad. Sci. USA, 96, 13978-13982.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 13978-13982
-
-
Snyder, S.H.1
-
76
-
-
0035796025
-
Functions of poly (ADP-ribose) polymerase (PARP) in DNA repair genomic integrity and cell death
-
Herceg,Z. and Wang,Z.Q. (2001) Functions of poly (ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat. Res., 477, 97-110.
-
(2001)
Mutat. Res.
, vol.477
, pp. 97-110
-
-
Herceg, Z.1
Wang, Z.Q.2
-
77
-
-
0015530539
-
Poly ADP-ribose glycohydrolase from rat liver nuclei a novel enzyme degrading the polymer
-
Ueda,K., Oka,J., Narumiya,S., Miyakawa,N. and Hayaishi,O. (1972) Poly ADP-ribose glycohydrolase from rat liver nuclei, a novel enzyme degrading the polymer. Biochem. Biophys. Res. Commun., 46, 516-523.
-
(1972)
Biochem. Biophys. Res. Commun.
, vol.46
, pp. 516-523
-
-
Miyakawa, N.1
Hayaishi, O.2
-
78
-
-
44949253890
-
Poly ADP-ribose polymerase-1: An international molecule of mystery
-
Woodhouse,B.C. and Dianov,G.L. (2008) Poly ADP-ribose polymerase-1: an international molecule of mystery. DNA Repair, 7, 1077-1086.
-
(2008)
DNA Repair
, vol.7
, pp. 1077-1086
-
-
Woodhouse, B.C.1
Dianov, G.L.2
-
79
-
-
0022834642
-
Modulation of chromatin superstructure induced by poly (ADP-ribose) synthesis and degradation
-
De Murcia,G., Huletsky,A., Lamarre,D., Gaudreau,A., Pouyet,J., Daune,M. and Poirier,G. (1986) Modulation of chromatin superstructure induced by poly (ADP-ribose) synthesis and degradation. J. Biol. Chem., 261, 7011-7017.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 7011-7017
-
-
De Murcia, G.1
Huletsky, A.2
Lamarre, D.3
Gaudreau, A.4
Pouyet, J.5
Daune, M.6
Poirier, G.7
-
80
-
-
84859766576
-
CHFR regulates the mitotic checkpoint by targeting PARP-1 for ubiquitination and degradation
-
Kashima,L., Idogawa,M., Mita,H., Shitashige,M., Yamada,T., Ogi,K., Suzuki,H., Toyota,M., Ariga,H. and Sasaki,Y. (2012) CHFR regulates the mitotic checkpoint by targeting PARP-1 for ubiquitination and degradation. J. Biol. Chem., 287, 12975-12984.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 12975-12984
-
-
Ariga, H.1
Sasaki, Y.2
|