MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner

DNA Repair

Volumn 10, Issue 8, 2011, Pages 806-814

  Strauss, Carmit ^a   Halevy, Tomer ^a   Macarov, Michal ^a   Argaman, Liron ^a   Goldberg, Michal ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

DNA double strand break; MDC1; RAP80; The DNA damage response; Ubiquitin interacting motif; Ubiquitylation

Indexed keywords

ADAPTOR PROTEIN; ANTIBODY; BRCA1 PROTEIN; GLUTATHIONE TRANSFERASE; MDC1 PROTEIN; RAP80 PROTEIN; SMALL INTERFERING RNA; UBIQUITIN CONJUGATING ENZYME 13; UNCLASSIFIED DRUG;

ANION EXCHANGE CHROMATOGRAPHY; ARTICLE; BINDING AFFINITY; DNA DAMAGE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOPRECIPITATION; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; UBIQUITINATION;

BRCA1 PROTEIN; CARRIER PROTEINS; DNA DAMAGE; HEK293 CELLS; HUMANS; LYSINE; MULTIPROTEIN COMPLEXES; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; TRANS-ACTIVATORS; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 79960700729     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2011.04.016     Document Type: Article

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