Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

EMBO Journal

Volumn 23, Issue 13, 2004, Pages 2674-2683

  Lukas, Claudia ^a   Melander, Fredrik ^a   Stucki, Manuel ^b   Falck, Jacob ^a,b   Bekker Jensen, Simon ^a   Goldberg, Michal ^b,d   Lerenthal, Yaniv ^c   Jackson, Stephen P ^b   Bartek, Jiri ^a   Lukas, Jiri ^a  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c TEL AVIV UNIVERSITY   (Israel)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Cell cycle checkpoints; DNA damage; Live cell imaging; Mdc1; Nbs1

Indexed keywords

DNA BINDING PROTEIN; DOUBLE STRANDED DNA; HISTONE H2A; NIBRIN; PROTEIN MDC1; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE;

ANTIBODIES, MONOCLONAL; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL NUCLEUS; CHROMATIN; DNA DAMAGE; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; HISTONES; HUMANS; HYDRAZINES; MICROSCOPY, CONFOCAL; NUCLEAR PROTEINS; OSTEOSARCOMA; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANS-ACTIVATORS;

EID: 3342915628     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600269     Document Type: Article

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