-
1
-
-
0018131605
-
The doctors' dilemma
-
Petersdorf RG. The doctors' dilemma. N. Engl. J. Med. 299(12), 628-634 (1978).
-
(1978)
N. Engl. J. Med.
, vol.299
, Issue.12
, pp. 628-634
-
-
Petersdorf, R.G.1
-
2
-
-
0022623604
-
Whither infectious diseases? Memories, manpower, and money
-
Petersdorf RG. Whither infectious diseases? Memories, manpower, and money. J. Infect. Dis. 153(2), 189-195 (1986).
-
(1986)
J. Infect. Dis.
, vol.153
, Issue.2
, pp. 189-195
-
-
Petersdorf, R.G.1
-
3
-
-
3142654211
-
The challenge of emerging and re-emerging infectious diseases
-
Morens DM, Folkers GK, Fauci AS. The challenge of emerging and re-emerging infectious diseases. Nature 430(6996), 242-249 (2004).
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 242-249
-
-
Morens, D.M.1
Folkers, G.K.2
Fauci, A.S.3
-
4
-
-
39749135587
-
Global trends in emerging infectious diseases
-
Jones KE, Patel NG, Levy MA et al. Global trends in emerging infectious diseases. Nature 451(7181), 990-993 (2008).
-
(2008)
Nature
, vol.451
, Issue.7181
, pp. 990-993
-
-
Jones, K.E.1
Patel, N.G.2
Levy, M.A.3
-
5
-
-
84885476368
-
Chemotherapy of pneumonia - with special reference to the present status of sulfadiazine
-
Finland M. Chemotherapy of pneumonia - with special reference to the present status of sulfadiazine. N. Engl. J. Med. 225, 187-195 (1941).
-
(1941)
N. Engl. J. Med.
, vol.225
, pp. 187-195
-
-
Finland, M.1
-
6
-
-
79953710021
-
Novel classes of antibiotics or more of the same?
-
Coates AR, Halls G, Hu Y. Novel classes of antibiotics or more of the same? Br. J. Pharmacol. 163(1), 184-194 (2011).
-
(2011)
Br. J. Pharmacol.
, vol.163
, Issue.1
, pp. 184-194
-
-
Coates, A.R.1
Halls, G.2
Hu, Y.3
-
7
-
-
79952815432
-
High burden of antimicrobial resistance in Asia
-
Jean SS, Hsueh PR. High burden of antimicrobial resistance in Asia. Int. J. Antimicrob. Agents 37(4), 291-295 (2011).
-
(2011)
Int. J. Antimicrob. Agents
, vol.37
, Issue.4
, pp. 291-295
-
-
Jean, S.S.1
Hsueh, P.R.2
-
8
-
-
84867754043
-
Prevalence of and risk factors for resistance to second-line drugs in people with multidrugresistant tuberculosis in eight countries: A prospective cohort study
-
Dalton T, Cegielski P, Akksilp S et al. Prevalence of and risk factors for resistance to second-line drugs in people with multidrugresistant tuberculosis in eight countries: A prospective cohort study. Lancet 380(9851), 1406-1417 (2012).
-
(2012)
Lancet
, vol.380
, Issue.9851
, pp. 1406-1417
-
-
Dalton, T.1
Cegielski, P.2
Akksilp, S.3
-
9
-
-
84863716178
-
Methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci, and other Gram-positives in healthcare
-
Calfee DP. Methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci, and other Gram-positives in healthcare. Curr. Opin. Infect. Dis. 25(4), 385-394 (2012).
-
(2012)
Curr. Opin. Infect. Dis.
, vol.25
, Issue.4
, pp. 385-394
-
-
Calfee, D.P.1
-
10
-
-
79955500873
-
Methicillin-resistant Staphylococcus aureus: The European landscape
-
Johnson AP. Methicillin-resistant Staphylococcus aureus: The European landscape. J. Antimicrob. Chemother. 66(Suppl. 4), iv43-iv48 (2011).
-
(2011)
J. Antimicrob. Chemother.
, vol.66
, Issue.SUPPL. 4
-
-
Johnson, A.P.1
-
11
-
-
84862868998
-
Current epidemiology and growing resistance of Gram-negative pathogens
-
Livermore DM. Current epidemiology and growing resistance of Gram-negative pathogens. Korean J. Intern. Med. 27(2), 128-142 (2012).
-
(2012)
Korean J. Intern. Med.
, vol.27
, Issue.2
, pp. 128-142
-
-
Livermore, D.M.1
-
12
-
-
77952298917
-
Hospital-acquired infections due to Gram-negative bacteria
-
Peleg AY, Hooper DC. Hospital-acquired infections due to Gram-negative bacteria. N. Engl. J. Med. 362(19), 1804-1813 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, Issue.19
, pp. 1804-1813
-
-
Peleg, A.Y.1
Hooper, D.C.2
-
13
-
-
59449088862
-
Antibiotic-resistant bugs in the 21st century - A clinical superchallenge
-
Arias CA, Murray BE. Antibiotic-resistant bugs in the 21st century - a clinical superchallenge. N. Engl. J. Med. 360(5), 439-443 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, Issue.5
, pp. 439-443
-
-
Arias, C.A.1
Murray, B.E.2
-
14
-
-
80051695875
-
Increasing prevalence and dissemination of NDM-1 metallo-beta-lactamase in India: Data from the SMART study 2009
-
Lascols C, Hackel M, Marshall SH et al. Increasing prevalence and dissemination of NDM-1 metallo-beta-lactamase in India: Data from the SMART study (2009). J. Antimicrob. Chemother. 66(9), 1992-1997 (2011).
-
(2011)
J. Antimicrob. Chemother.
, vol.66
, Issue.9
, pp. 1992-1997
-
-
Lascols, C.1
Hackel, M.2
Marshall, S.H.3
-
15
-
-
79960959584
-
Multiresistant Gram-negative bacteria: The role of high-risk clones in the dissemination of antibiotic resistance
-
Woodford N, Turton JF, Livermore DM. Multiresistant Gram-negative bacteria: The role of high-risk clones in the dissemination of antibiotic resistance. FEMS Microbiol. Rev. 35(5), 736-755 (2011).
-
(2011)
FEMS Microbiol. Rev.
, vol.35
, Issue.5
, pp. 736-755
-
-
Woodford, N.1
Turton, J.F.2
Livermore, D.M.3
-
16
-
-
84864379255
-
In vivo emergence of tigecycline resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli
-
Spanu T, De Angelis G, Cipriani M et al. In vivo emergence of tigecycline resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli. Antimicrob. Agents Chemother. 56(8), 4516-4518 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, Issue.8
, pp. 4516-4518
-
-
Spanu, T.1
De Angelis, G.2
Cipriani, M.3
-
17
-
-
80051692552
-
Efficacy and safety of tigecycline: A systematic review and meta-analysis
-
Yahav D, Lador A, Paul M, Leibovici L. Efficacy and safety of tigecycline: A systematic review and meta-analysis. J. Antimicrob. Chemother. 66(9), 1963-1971 (2011).
-
(2011)
J. Antimicrob. Chemother.
, vol.66
, Issue.9
, pp. 1963-1971
-
-
Yahav, D.1
Lador, A.2
Paul, M.3
Leibovici, L.4
-
18
-
-
77955516386
-
Hospital outbreak caused by Klebsiella pneumoniae producing KPC-2 beta-lactamase resistant to colistin
-
Kontopoulou K, Protonotariou E, Vasilakos K et al. Hospital outbreak caused by Klebsiella pneumoniae producing KPC-2 beta-lactamase resistant to colistin. J. Hosp. Infect. 76(1), 70-73 (2010).
-
(2010)
J. Hosp. Infect.
, vol.76
, Issue.1
, pp. 70-73
-
-
Kontopoulou, K.1
Protonotariou, E.2
Vasilakos, K.3
-
19
-
-
80052901099
-
Prevalence of faecal carriage of Enterobacteriaceae with NDM-1 carbapenemase at military hospitals in Pakistan, and evaluation of two chromogenic media
-
Perry JD, Naqvi SH, Mirza IA et al. Prevalence of faecal carriage of Enterobacteriaceae with NDM-1 carbapenemase at military hospitals in Pakistan, and evaluation of two chromogenic media. J. Antimicrob. Chemother. 66(10), 2288-2294 (2011).
-
(2011)
J. Antimicrob. Chemother.
, vol.66
, Issue.10
, pp. 2288-2294
-
-
Perry, J.D.1
Naqvi, S.H.2
Mirza, I.A.3
-
20
-
-
79953756522
-
Foodborne nosocomial outbreak of SHV1 and CTX-M-15-producing Klebsiella pneumoniae: Epidemiology and control
-
Calbo E, Freixas N, Xercavins M et al. Foodborne nosocomial outbreak of SHV1 and CTX-M-15-producing Klebsiella pneumoniae: Epidemiology and control. Clin. Infect. Dis. 52(6), 743-749 (2011).
-
(2011)
Clin. Infect. Dis.
, vol.52
, Issue.6
, pp. 743-749
-
-
Calbo, E.1
Freixas, N.2
Xercavins, M.3
-
21
-
-
79955468462
-
Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: An environmental point prevalence study
-
Walsh TR, Weeks J, Livermore DM, Toleman MA. Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: An environmental point prevalence study. Lancet Infect. Dis. 11(5), 355-362 (2011).
-
(2011)
Lancet Infect. Dis.
, vol.11
, Issue.5
, pp. 355-362
-
-
Walsh, T.R.1
Weeks, J.2
Livermore, D.M.3
Toleman, M.A.4
-
22
-
-
33846153776
-
Infectious diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship
-
Dellit TH, Owens RC, McGowan JE Jr et al. Infectious diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin. Infect. Dis. 44(2), 159-177 (2007).
-
(2007)
Clin. Infect. Dis.
, vol.44
, Issue.2
, pp. 159-177
-
-
Dellit, T.H.1
Owens, R.C.2
McGowan Jr., J.E.3
-
23
-
-
79959306747
-
Antibiotic resistance gene spread due to manure application on agricultural fields
-
Heuer H, Schmitt H, Smalla K. Antibiotic resistance gene spread due to manure application on agricultural fields. Curr. Opin. Microbiol. 14(3), 236-243 (2011).
-
(2011)
Curr. Opin. Microbiol.
, vol.14
, Issue.3
, pp. 236-243
-
-
Heuer, H.1
Schmitt, H.2
Smalla, K.3
-
24
-
-
84865531061
-
The shared antibiotic resistome of soil bacteria and human pathogens
-
Forsberg KJ, Reyes A, Wang B, Selleck EM, Sommer MO, Dantas G. The shared antibiotic resistome of soil bacteria and human pathogens. Science 337(6098), 1107-1111 (2012).
-
(2012)
Science
, vol.337
, Issue.6098
, pp. 1107-1111
-
-
Forsberg, K.J.1
Reyes, A.2
Wang, B.3
Selleck, E.M.4
Sommer, M.O.5
Dantas, G.6
-
25
-
-
84862310088
-
Immunotherapies in infectious diseases
-
ix
-
Kak V, Sundareshan V, Modi J, Khardori NM. Immunotherapies in infectious diseases. Med. Clin. N. Am. 96(3), 455-474, ix (2012).
-
(2012)
Med. Clin. N. Am.
, vol.96
, Issue.3
, pp. 455-474
-
-
Kak V Sundareshan, V.1
Modi, J.2
Khardori, N.M.3
-
26
-
-
84882886880
-
The three original publications on vaccination against smallpox
-
Jenner E. The three original publications on vaccination against smallpox. Harvard Classics 38(4), 1-14 (1909).
-
(1909)
Harvard Classics
, vol.38
, Issue.4
, pp. 1-14
-
-
Jenner, E.1
-
27
-
-
33847175919
-
Live bacterial vaccines - A review and identification of potential hazards
-
Detmer A, Glenting J. Live bacterial vaccines - a review and identification of potential hazards. Microb. Cell Fact. 5, 23 (2006).
-
(2006)
Microb. Cell Fact.
, vol.5
, pp. 23
-
-
Detmer, A.1
Glenting, J.2
-
28
-
-
79952488544
-
Immune protection against tuberculosis - when is immunotherapy preferable to vaccination?
-
Grange JM, Brunet LR, Rieder HL. Immune protection against tuberculosis - when is immunotherapy preferable to vaccination? Tuberculosis (Edinb.) 91(2), 179-185 (2011).
-
(2011)
Tuberculosis (Edinb.)
, vol.91
, Issue.2
, pp. 179-185
-
-
Grange, J.M.1
Brunet, L.R.2
Rieder, H.L.3
-
29
-
-
0024955886
-
Approaching the asymptote? Evolution and revolution in immunology
-
Janeway CA Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 54(Pt 1), 1-13 (1989).
-
(1989)
Cold Spring Harb. Symp. Quant. Biol.
, vol.54
, Issue.PART 1
, pp. 1-13
-
-
Janeway Jr., C.A.1
-
30
-
-
0037066502
-
Decoding the patterns of self and nonself by the innate immune system
-
Medzhitov R, Janeway CA Jr. Decoding the patterns of self and nonself by the innate immune system. Science 296(5566), 298-300 (2002).
-
(2002)
Science
, vol.296
, Issue.5566
, pp. 298-300
-
-
Medzhitov, R.1
Janeway Jr., C.A.2
-
32
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
Medzhitov R. Recognition of microorganisms and activation of the immune response. Nature 449(7164), 819-826 (2007).
-
(2007)
Nature
, vol.449
, Issue.7164
, pp. 819-826
-
-
Medzhitov, R.1
-
34
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A, Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 327(5963), 291-295 (2010).
-
(2010)
Science
, vol.327
, Issue.5963
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
35
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 453(7198), 1122-1126 (2008).
-
(2008)
Nature
, vol.453
, Issue.7198
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
36
-
-
79960608092
-
Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88
-
Seubert A, Calabro S, Santini L et al. Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88. Proc. Natl Acad. Sci. USA 108(27), 11169-11174 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, Issue.27
, pp. 11169-11174
-
-
Seubert, A.1
Calabro, S.2
Santini, L.3
-
37
-
-
84857546470
-
Beyond pattern recognition: Five immune checkpoints for scaling the microbial threat
-
Blander JM, Sander LE. Beyond pattern recognition: Five immune checkpoints for scaling the microbial threat. Nat. Rev. Immunol. 12(3), 215-225 (2012).
-
(2012)
Nat. Rev. Immunol.
, vol.12
, Issue.3
, pp. 215-225
-
-
Blander, J.M.1
Sander, L.E.2
-
38
-
-
67651091732
-
Patterns of pathogenesis: Discrimination of pathogenic and nonpathogenic microbes by the innate immune system
-
Vance RE, Isberg RR, Portnoy DA. Patterns of pathogenesis: Discrimination of pathogenic and nonpathogenic microbes by the innate immune system. Cell Host Microb. 6(1), 10-21 (2009).
-
(2009)
Cell Host Microb.
, vol.6
, Issue.1
, pp. 10-21
-
-
Vance, R.E.1
Isberg, R.R.2
Portnoy, D.A.3
-
39
-
-
84866279077
-
Improved vaccines through targeted manipulation of the body's immunological risk-assessment?
-
Sander LE. Improved vaccines through targeted manipulation of the body's immunological risk-assessment? Bioessays 34(10), 876-884 (2012).
-
(2012)
Bioessays
, vol.34
, Issue.10
, pp. 876-884
-
-
Sander, L.E.1
-
40
-
-
79959242498
-
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity
-
Sander LE, Davis MJ, Boekschoten MV et al. Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature 474(7351), 385-389 (2011).
-
(2011)
Nature
, vol.474
, Issue.7351
, pp. 385-389
-
-
Sander, L.E.1
Davis, M.J.2
Boekschoten, M.V.3
-
41
-
-
0035941095
-
Priming of memory but not effector CD8 T cells by a killed bacterial vaccine
-
Lauvau G, Vijh S, Kong P et al. Priming of memory but not effector CD8 T cells by a killed bacterial vaccine. Science 294(5547), 1735-1739 (2001).
-
(2001)
Science
, vol.294
, Issue.5547
, pp. 1735-1739
-
-
Lauvau, G.1
Vijh, S.2
Kong, P.3
-
42
-
-
0028068298
-
Antigen provoking gamma interferon production in response to Mycobacterium bovis BCG and functional difference in T-cell responses to this antigen between viable and killed BCGimmunized mice
-
Kawamura I, Yang J, Takaesu Y, Fujita M, Nomoto K, Mitsuyama M. Antigen provoking gamma interferon production in response to Mycobacterium bovis BCG and functional difference in T-cell responses to this antigen between viable and killed BCGimmunized mice. Infect. Immun. 62(10), 4396-4403 (1994).
-
(1994)
Infect. Immun.
, vol.62
, Issue.10
, pp. 4396-4403
-
-
Kawamura, I.1
Yang, J.2
Takaesu, Y.3
Fujita, M.4
Nomoto, K.5
Mitsuyama, M.6
-
43
-
-
84864600268
-
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by Gram-negative bacteria
-
Rathinam VA, Vanaja SK, Waggoner L et al. TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by Gram-negative bacteria. Cell 150(3), 606-619 (2012).
-
(2012)
Cell
, vol.150
, Issue.3
, pp. 606-619
-
-
Rathinam, V.A.1
Vanaja, S.K.2
Waggoner, L.3
-
44
-
-
84867241369
-
Toll or interleukin-1 receptor (TIR) domaincontaining adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasomemediated host defense against enteropathogens
-
Gurung P, Malireddi RK, Anand PK et al. Toll or interleukin-1 receptor (TIR) domaincontaining adaptor inducing interferon-beta (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasomemediated host defense against enteropathogens. J. Biol. Chem. 287(41), 34474-34483 (2012).
-
(2012)
J. Biol. Chem.
, vol.287
, Issue.41
, pp. 34474-34483
-
-
Gurung, P.1
Malireddi, R.K.2
Anand, P.K.3
-
45
-
-
84855485784
-
Host innate recognition of an intestinal bacterial pathogen induces TRIF-dependent protective immunity
-
Sotolongo J, Espana C, Echeverry A et al. Host innate recognition of an intestinal bacterial pathogen induces TRIF-dependent protective immunity. J. Exp. Med. 208(13), 2705-2716 (2011).
-
(2011)
J. Exp. Med.
, vol.208
, Issue.13
, pp. 2705-2716
-
-
Sotolongo, J.1
Espana, C.2
Echeverry, A.3
-
46
-
-
33847373551
-
Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF)-mediated signaling contributes to innate immune responses in the lung during Escherichia coli pneumonia
-
Jeyaseelan S, Young SK, Fessler MB et al. Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF)-mediated signaling contributes to innate immune responses in the lung during Escherichia coli pneumonia. J. Immunol. 178(5), 3153-3160 (2007).
-
(2007)
J. Immunol.
, vol.178
, Issue.5
, pp. 3153-3160
-
-
Jeyaseelan, S.1
Young, S.K.2
Fessler, M.B.3
-
47
-
-
77954070545
-
C-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response
-
Woodward JJ, Iavarone AT, Portnoy DA. c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 328(5986), 1703-1705 (2010).
-
(2010)
Science
, vol.328
, Issue.5986
, pp. 1703-1705
-
-
Woodward, J.J.1
Iavarone, A.T.2
Portnoy, D.A.3
-
48
-
-
80054966913
-
STING is a direct innate immune sensor of cyclic di-GMP
-
Burdette DL, Monroe KM, Sotelo-Troha K et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature 478(7370), 515-518 (2011).
-
(2011)
Nature
, vol.478
, Issue.7370
, pp. 515-518
-
-
Burdette, D.L.1
Monroe, K.M.2
Sotelo-Troha, K.3
-
49
-
-
84869403247
-
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response
-
Parvatiyar K, Zhang Z, Teles RM et al. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat. Immunol. 13(12), 1155-1161 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, Issue.12
, pp. 1155-1161
-
-
Parvatiyar, K.1
Zhang, Z.2
Teles, R.M.3
-
50
-
-
34447564221
-
Look who's talking: Communication and quorum sensing in the bacterial world
-
Williams P, Winzer K, Chan WC, Camara M. Look who's talking: Communication and quorum sensing in the bacterial world. Philos. Trans. R. Soc. Lond. B Biol. Sci. 362(1483), 1119-1134 (2007).
-
(2007)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.362
, Issue.1483
, pp. 1119-1134
-
-
Williams, P.1
Winzer, K.2
Chan, W.C.3
Camara, M.4
-
51
-
-
47249129511
-
Modulation of gene expression via disruption of NF-kappaB signaling by a bacterial small molecule
-
Kravchenko VV, Kaufmann GF, Mathison JC et al. Modulation of gene expression via disruption of NF-kappaB signaling by a bacterial small molecule. Science 321(5886), 259-263 (2008).
-
(2008)
Science
, vol.321
, Issue.5886
, pp. 259-263
-
-
Kravchenko, V.V.1
Kaufmann, G.F.2
Mathison, J.C.3
-
52
-
-
84865985363
-
Regulation on expression of Toll-like receptors on monocytes after stimulation with the 3-o-C12-HSL molecule from Pseudomonas aeruginosa
-
Lu Q, Lin Y, Yang X et al. Regulation on expression of Toll-like receptors on monocytes after stimulation with the 3-o-C12-HSL molecule from Pseudomonas aeruginosa. Curr. Microbiol. 65(4), 384-389 (2012).
-
(2012)
Curr. Microbiol.
, vol.65
, Issue.4
, pp. 384-389
-
-
Lu, Q.1
Lin, Y.2
Yang, X.3
-
53
-
-
33846091738
-
The quorum-sensing molecule N-3-oxododecanoyl homoserine lactone (3OC12-HSL) enhances the host defence by activating human polymorphonuclear neutrophils (PMN)
-
Wagner C, Zimmermann S, Brenner-Weiss G et al. The quorum-sensing molecule N-3- oxododecanoyl homoserine lactone (3OC12- HSL) enhances the host defence by activating human polymorphonuclear neutrophils (PMN). Anal. Bioanal. Chem. 387(2), 481-487 (2007).
-
(2007)
Anal. Bioanal. Chem.
, vol.387
, Issue.2
, pp. 481-487
-
-
Wagner, C.1
Zimmermann, S.2
Brenner-Weiss, G.3
-
54
-
-
76249108958
-
Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3
-
Meixenberger K, Pache F, Eitel J et al. Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3. J. Immunol. 184(2), 922-930 (2010).
-
(2010)
J. Immunol.
, vol.184
, Issue.2
, pp. 922-930
-
-
Meixenberger, K.1
Pache, F.2
Eitel, J.3
-
55
-
-
79960408020
-
The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia
-
Witzenrath M, Pache F, Lorenz D et al. The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia. J. Immunol. 187(1), 434-440 (2011).
-
(2011)
J. Immunol.
, vol.187
, Issue.1
, pp. 434-440
-
-
Witzenrath, M.1
Pache, F.2
Lorenz, D.3
-
56
-
-
70349334298
-
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureusinduced activation of the Nlrp3 inflammasome
-
Munoz-Planillo R, Franchi L, Miller LS, Nunez G. A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureusinduced activation of the Nlrp3 inflammasome. J. Immunol. 183(6), 3942-3948 (2009).
-
(2009)
J. Immunol.
, vol.183
, Issue.6
, pp. 3942-3948
-
-
Munoz-Planillo, R.1
Franchi, L.2
Miller, L.S.3
Nunez, G.4
-
57
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477(7366), 592-595 (2011).
-
(2011)
Nature
, vol.477
, Issue.7366
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
58
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden ED, Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat. Genet. 38(2), 240-244 (2006).
-
(2006)
Nat. Genet.
, vol.38
, Issue.2
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
60
-
-
84859489110
-
CpG still rocks! Update on an accidental drug
-
Krieg AM. CpG still rocks! Update on an accidental drug. Nucleic Acid Ther. 22(2), 77-89 (2012).
-
(2012)
Nucleic Acid Ther.
, vol.22
, Issue.2
, pp. 77-89
-
-
Krieg, A.M.1
-
62
-
-
84862851678
-
Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections
-
Zhang X, Kraft A, Broering R, Schlaak JF, Dittmer U, Lu M. Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections. Expert Opin. Drug Discov. 7(7), 597-611 (2012).
-
(2012)
Expert Opin. Drug Discov.
, vol.7
, Issue.7
, pp. 597-611
-
-
Zhang, X.1
Kraft, A.2
Broering, R.3
Schlaak, J.F.4
Dittmer, U.5
Lu, M.6
-
63
-
-
84860739314
-
Targeting pattern recognition receptors in cancer immunotherapy
-
Goutagny N, Estornes Y, Hasan U, Lebecque S, Caux C. Targeting pattern recognition receptors in cancer immunotherapy. Target Oncol. 7(1), 29-54 (2012).
-
(2012)
Target Oncol.
, vol.7
, Issue.1
, pp. 29-54
-
-
Goutagny, N.1
Estornes, Y.2
Hasan, U.3
Lebecque, S.4
Caux, C.5
-
64
-
-
84858381864
-
Modulating immunity as a therapy for bacterial infections
-
Hancock RE, Nijnik A, Philpott DJ. Modulating immunity as a therapy for bacterial infections. Nat. Rev. Microbiol. 10(4), 243-254 (2012).
-
(2012)
Nat. Rev. Microbiol.
, vol.10
, Issue.4
, pp. 243-254
-
-
Hancock, R.E.1
Nijnik, A.2
Philpott, D.J.3
-
66
-
-
77955554892
-
The viral TLR3 agonist poly(I:C) stimulates phagocytosis and intracellular killing of Escherichia coli by microglial cells
-
Ribes S, Adam N, Ebert S et al. The viral TLR3 agonist poly(I:C) stimulates phagocytosis and intracellular killing of Escherichia coli by microglial cells. Neurosci. Lett. 482(1), 17-20 (2010).
-
(2010)
Neurosci. Lett.
, vol.482
, Issue.1
, pp. 17-20
-
-
Ribes, S.1
Adam, N.2
Ebert, S.3
-
67
-
-
58449119213
-
Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells
-
Ribes S, Ebert S, Czesnik D et al. Toll-like receptor prestimulation increases phagocytosis of Escherichia coli DH5alpha and Escherichia coli K1 strains by murine microglial cells. Infect. Immun. 77(1), 557-564 (2009).
-
(2009)
Infect. Immun.
, vol.77
, Issue.1
, pp. 557-564
-
-
Ribes, S.1
Ebert, S.2
Czesnik, D.3
-
68
-
-
63349095712
-
Immunostimulation with macrophageactivating lipopeptide-2 increased survival in murine pneumonia
-
Reppe K, Tschernig T, Luhrmann A et al. Immunostimulation with macrophageactivating lipopeptide-2 increased survival in murine pneumonia. Am. J. Respir. Cell Mol. Biol. 40(4), 474-481 (2009).
-
(2009)
Am. J. Respir. Cell Mol. Biol.
, vol.40
, Issue.4
, pp. 474-481
-
-
Reppe, K.1
Tschernig, T.2
Luhrmann, A.3
-
69
-
-
34250854079
-
The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4
-
Mata-Haro V, Cekic C, Martin M, Chilton PM, Casella CR, Mitchell TC. The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science 316(5831), 1628-1632 (2007).
-
(2007)
Science
, vol.316
, Issue.5831
, pp. 1628-1632
-
-
Mata-Haro, V.1
Cekic, C.2
Martin, M.3
Chilton, P.M.4
Casella, C.R.5
Mitchell, T.C.6
-
70
-
-
51149120166
-
Induction of innate immunity by lipid A mimetics increases survival from pneumonic plague
-
Airhart CL, Rohde HN, Bohach GA et al. Induction of innate immunity by lipid A mimetics increases survival from pneumonic plague. Microbiology 154(Pt 7), 2131-2138 (2008).
-
(2008)
Microbiology
, vol.154
, Issue.PART 7
, pp. 2131-2138
-
-
Airhart, C.L.1
Rohde, H.N.2
Bohach, G.A.3
-
71
-
-
20244369887
-
Synthetic Toll-like receptor 4 agonists stimulate innate resistance to infectious challenge
-
Cluff CW, Baldridge JR, Stover AG et al. Synthetic Toll-like receptor 4 agonists stimulate innate resistance to infectious challenge. Infect. Immun. 73(5), 3044-3052 (2005).
-
(2005)
Infect. Immun.
, vol.73
, Issue.5
, pp. 3044-3052
-
-
Cluff, C.W.1
Baldridge, J.R.2
Stover, A.G.3
-
72
-
-
80755126966
-
Monophosphoryl lipid A induced innate immune responses via TLR4 to enhance clearance of nontypeable Haemophilus influenzae and Moraxella catarrhalis from the nasopharynx in mice
-
Hirano T, Kodama S, Kawano T, Maeda K, Suzuki M. Monophosphoryl lipid A induced innate immune responses via TLR4 to enhance clearance of nontypeable Haemophilus influenzae and Moraxella catarrhalis from the nasopharynx in mice. FEMS Immunol. Med. Microbiol. 63(3), 407-417 (2011).
-
(2011)
FEMS Immunol. Med. Microbiol.
, vol.63
, Issue.3
, pp. 407-417
-
-
Hirano, T.1
Kodama, S.2
Kawano, T.3
Maeda, K.4
Suzuki, M.5
-
73
-
-
77957728392
-
Mucosal administration of flagellin protects mice from Streptococcus pneumoniae lung infection
-
Munoz N, Van Maele L, Marques JM, Rial A, Sirard JC, Chabalgoity JA. Mucosal administration of flagellin protects mice from Streptococcus pneumoniae lung infection. Infect. Immun. 78(10), 4226-4233 (2010).
-
(2010)
Infect. Immun.
, vol.78
, Issue.10
, pp. 4226-4233
-
-
Munoz, N.1
Van Maele, L.2
Marques, J.M.3
Rial, A.4
Sirard, J.C.5
Chabalgoity, J.A.6
-
74
-
-
77955494032
-
Flagellin stimulates protective lung mucosal immunity: Role of cathelicidin-related antimicrobial peptide
-
Yu FS, Cornicelli MD, Kovach MA et al. Flagellin stimulates protective lung mucosal immunity: Role of cathelicidin-related antimicrobial peptide. J. Immunol. 185(2), 1142-1149 (2010).
-
(2010)
J. Immunol.
, vol.185
, Issue.2
, pp. 1142-1149
-
-
Yu, F.S.1
Cornicelli, M.D.2
Kovach, M.A.3
-
75
-
-
38649123396
-
The future of Toll-like receptor therapeutics
-
Parkinson T. The future of Toll-like receptor therapeutics. Curr. Opin. Mol. Ther. 10(1), 21-31 (2008).
-
(2008)
Curr. Opin. Mol. Ther.
, vol.10
, Issue.1
, pp. 21-31
-
-
Parkinson, T.1
-
76
-
-
0034775973
-
Efficacy of a polyvalent bacterial lysate in children with recurrent respiratory tract infections
-
Ruah SB, Ruah C, Van Aubel A, Abel S, Elsasser U. Efficacy of a polyvalent bacterial lysate in children with recurrent respiratory tract infections. Adv. Ther. 18(4), 151-162 (2001).
-
(2001)
Adv. Ther.
, vol.18
, Issue.4
, pp. 151-162
-
-
Ruah, S.B.1
Ruah, C.2
Van Aubel, A.3
Abel, S.4
Elsasser, U.5
-
77
-
-
8744268499
-
Oral purified bacterial extracts in chronic bronchitis and COPD: Systematic review
-
Steurer-Stey C, Bachmann LM, Steurer J, Tramer MR. Oral purified bacterial extracts in chronic bronchitis and COPD: Systematic review. Chest 126(5), 1645-1655 (2004).
-
(2004)
Chest
, vol.126
, Issue.5
, pp. 1645-1655
-
-
Steurer-Stey, C.1
Bachmann, L.M.2
Steurer, J.3
Tramer, M.R.4
-
78
-
-
45849140258
-
Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia
-
Lembo A, Pelletier M, Iyer R et al. Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia. J. Immunol. 180(11), 7574-7581 (2008).
-
(2008)
J. Immunol.
, vol.180
, Issue.11
, pp. 7574-7581
-
-
Lembo, A.1
Pelletier, M.2
Iyer, R.3
-
79
-
-
79952300209
-
TLR signaling is required for Salmonella typhimurium virulence
-
Arpaia N, Godec J, Lau L et al. TLR signaling is required for Salmonella typhimurium virulence. Cell 144(5), 675-688 (2011).
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 675-688
-
-
Arpaia, N.1
Godec, J.2
Lau, L.3
-
80
-
-
84855184185
-
Prophylactic and therapeutic implications of Toll-like receptor ligands
-
Hedayat M, Takeda K, Rezaei N. Prophylactic and therapeutic implications of Toll-like receptor ligands. Med. Res. Rev. 32(2), 294-325 (2010).
-
(2010)
Med. Res. Rev.
, vol.32
, Issue.2
, pp. 294-325
-
-
Hedayat, M.1
Takeda, K.2
Rezaei, N.3
-
81
-
-
4544356741
-
Topical imiquimod 5% cream in external anogenital warts: A randomized, double-blind, placebo-controlled study
-
Arican O, Guneri F, Bilgic K, Karaoglu A. Topical imiquimod 5% cream in external anogenital warts: A randomized, double-blind, placebo-controlled study. J. Dermatol. 31(8), 627-631 (2004).
-
(2004)
J. Dermatol.
, vol.31
, Issue.8
, pp. 627-631
-
-
Arican, O.1
Guneri, F.2
Bilgic, K.3
Karaoglu, A.4
-
82
-
-
83655182790
-
Successful treatment of aciclovir and foscarnet resistant Herpes simplex virus lesions with topical imiquimod in patients infected with human immunodeficiency virus type 1
-
Lascaux AS, Caumes E, Deback C et al. Successful treatment of aciclovir and foscarnet resistant Herpes simplex virus lesions with topical imiquimod in patients infected with human immunodeficiency virus type 1. J. Med. Virol. 84(2), 194-197 (2012).
-
(2012)
J. Med. Virol.
, vol.84
, Issue.2
, pp. 194-197
-
-
Lascaux, A.S.1
Caumes, E.2
Deback, C.3
-
83
-
-
34347399259
-
Oral resiquimod in chronic HCV infection: Safety and efficacy in 2 placebo-controlled, doubleblind Phase IIa studies
-
Pockros PJ, Guyader D, Patton H et al. Oral resiquimod in chronic HCV infection: Safety and efficacy in 2 placebo-controlled, doubleblind Phase IIa studies. J. Hepatol. 47(2), 174-182 (2007).
-
(2007)
J. Hepatol.
, vol.47
, Issue.2
, pp. 174-182
-
-
Pockros, P.J.1
Guyader, D.2
Patton, H.3
-
84
-
-
79960554471
-
Randomised clinical trial: Anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV
-
Bergmann JF, de Bruijne J, Hotho DM et al. Randomised clinical trial: Anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV. Aliment. Pharmacol. Ther. 34(4), 443-453 (2011).
-
(2011)
Aliment. Pharmacol. Ther.
, vol.34
, Issue.4
, pp. 443-453
-
-
Bergmann, J.F.1
De Bruijne, J.2
Hotho, D.M.3
-
85
-
-
79956066252
-
Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin
-
Sousa Mda G, Reid DM, Schweighoffer E et al. Restoration of pattern recognition receptor costimulation to treat chromoblastomycosis, a chronic fungal infection of the skin. Cell Host Microbe 9(5), 436-443 (2011).
-
(2011)
Cell Host Microbe
, vol.9
, Issue.5
, pp. 436-443
-
-
Sousa Mda, G.1
Reid, D.M.2
Schweighoffer, E.3
-
86
-
-
84055190795
-
Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency
-
Sancho-Shimizu V, Perez De Diego R, Lorenzo L et al. Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency. J. Clin. Invest. 121(12), 4889-4902 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, Issue.12
, pp. 4889-4902
-
-
Sancho-Shimizu, V.1
Perez De Diego, R.2
Lorenzo, L.3
-
87
-
-
48749109290
-
Pyogenic bacterial infections in humans with MyD88 deficiency
-
von Bernuth H, Picard C, Jin Z et al. Pyogenic bacterial infections in humans with MyD88 deficiency. Science 321(5889), 691-696 (2008).
-
(2008)
Science
, vol.321
, Issue.5889
, pp. 691-696
-
-
Von Bernuth, H.1
Picard, C.2
Jin, Z.3
-
88
-
-
77953316015
-
Both TRIF and MyD88-dependent signaling contribute to host defense against pulmonary Klebsiella infection
-
Cai S, Batra S, Shen L, Wakamatsu N, Jeyaseelan S. Both TRIF- and MyD88- dependent signaling contribute to host defense against pulmonary Klebsiella infection. J. Immunol. 183(10), 6629-6638 (2009).
-
(2009)
J. Immunol.
, vol.183
, Issue.10
, pp. 6629-6638
-
-
Cai, S.1
Batra, S.2
Shen, L.3
Wakamatsu, N.4
Jeyaseelan, S.5
-
89
-
-
39149116674
-
NLR, the nucleotide-binding domain leucine-rich repeat containing gene family
-
Ye Z, Ting JP. NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. Curr. Opin. Immunol. 20(1), 3-9 (2008).
-
(2008)
Curr. Opin. Immunol.
, vol.20
, Issue.1
, pp. 3-9
-
-
Ye, Z.1
Ting, J.P.2
-
90
-
-
33846330896
-
Nod-like proteins in immunity, inflammation and disease
-
Fritz JH, Ferrero RL, Philpott DJ, Girardin SE. Nod-like proteins in immunity, inflammation and disease. Nat. Immunol. 7(12), 1250-1257 (2006).
-
(2006)
Nat. Immunol.
, vol.7
, Issue.12
, pp. 1250-1257
-
-
Fritz, J.H.1
Ferrero, R.L.2
Philpott, D.J.3
Girardin, S.E.4
-
91
-
-
78751620798
-
NLR functions beyond pathogen recognition
-
Kufer TA, Sansonetti PJ. NLR functions beyond pathogen recognition. Nat. Immunol. 12(2), 121-128 (2011).
-
(2011)
Nat. Immunol.
, vol.12
, Issue.2
, pp. 121-128
-
-
Kufer, T.A.1
Sansonetti, P.J.2
-
92
-
-
34548441212
-
Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing
-
Lysenko ES, Clarke TB, Shchepetov M et al. Nod1 signaling overcomes resistance of S. pneumoniae to opsonophagocytic killing. PLoS Pathog. 3(8), e118 (2007).
-
(2007)
PLoS Pathog.
, vol.3
, Issue.8
-
-
Lysenko, E.S.1
Clarke, T.B.2
Shchepetov, M.3
-
93
-
-
44949093419
-
Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice
-
Clement CG, Evans SE, Evans CM et al. Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice. Am. J. Respir. Crit. Care Med. 177(12), 1322-1330 (2008).
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.177
, Issue.12
, pp. 1322-1330
-
-
Clement, C.G.1
Evans, S.E.2
Evans, C.M.3
-
94
-
-
73949118392
-
Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi
-
Evans SE, Scott BL, Clement CG et al. Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi. Am. J. Respir. Cell Mol. Biol. 42(1), 40-50 (2010).
-
(2010)
Am. J. Respir. Cell Mol. Biol.
, vol.42
, Issue.1
, pp. 40-50
-
-
Evans, S.E.1
Scott, B.L.2
Clement, C.G.3
-
95
-
-
76249120134
-
Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity
-
Clarke TB, Davis KM, Lysenko ES, Zhou AY, Yu Y, Weiser JN. Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat. Med. 16(2), 228-231 (2010).
-
(2010)
Nat. Med.
, vol.16
, Issue.2
, pp. 228-231
-
-
Clarke, T.B.1
Davis, K.M.2
Lysenko, E.S.3
Zhou, A.Y.4
Yu, Y.5
Weiser, J.N.6
-
96
-
-
57649184660
-
Analogues of muramyl dipeptide (MDP)rfeti and tuftsin limit infection and inflammation in murine model of sepsis
-
Wardowska A, Dzierzbicka K, Szarynska M et al. Analogues of muramyl dipeptide (MDP) and tuftsin limit infection and inflammation in murine model of sepsis. Vaccine 27(3), 369-374 (2009).
-
(2009)
Vaccine
, vol.27
, Issue.3
, pp. 369-374
-
-
Wardowska, A.1
Dzierzbicka, K.2
Szarynska, M.3
-
97
-
-
84860241844
-
NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans
-
Juarez E, Carranza C, Hernandez-Sanchez F et al. NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans. Eur. J. Immunol. 42(4), 880-889 (2012).
-
(2012)
Eur. J. Immunol.
, vol.42
, Issue.4
, pp. 880-889
-
-
Juarez, E.1
Carranza, C.2
Hernandez-Sanchez, F.3
-
98
-
-
58149189054
-
NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity
-
Divangahi M, Mostowy S, Coulombe F et al. NOD2-deficient mice have impaired resistance to Mycobacterium tuberculosis infection through defective innate and adaptive immunity. J. Immunol. 181(10), 7157-7165 (2008).
-
(2008)
J. Immunol.
, vol.181
, Issue.10
, pp. 7157-7165
-
-
Divangahi, M.1
Mostowy, S.2
Coulombe, F.3
-
99
-
-
0014124597
-
Inducers of interferon and host resistance II. Multistranded synthetic polynucleotide complexes
-
Field AK, Tytell AA, Lampson GP, Hilleman MR. Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes. Proc. Natl Acad. Sci. USA 58(3), 1004-1010 (1967).
-
(1967)
Proc. Natl Acad. Sci. USA
, vol.58
, Issue.3
, pp. 1004-1010
-
-
Field, A.K.1
Tytell, A.A.2
Lampson, G.P.3
Hilleman, M.R.4
-
100
-
-
77958498224
-
Vaccine adjuvants: Putting innate immunity to work
-
Coffman RL, Sher A, Seder RA. Vaccine adjuvants: Putting innate immunity to work. Immunity 33(4), 492-503 (2010).
-
(2010)
Immunity
, vol.33
, Issue.4
, pp. 492-503
-
-
Coffman, R.L.1
Sher, A.2
Seder, R.A.3
-
101
-
-
54349121628
-
Interferon protects mice against inhalation anthrax
-
Walberg K, Baron S, Poast J et al. Interferon protects mice against inhalation anthrax. J. Interferon Cytokine Res. 28(10), 597-601 (2008).
-
(2008)
J. Interferon Cytokine Res.
, vol.28
, Issue.10
, pp. 597-601
-
-
Walberg, K.1
Baron, S.2
Poast, J.3
-
102
-
-
77950220938
-
Toll-like receptor 3 agonist protection against experimental Francisella tularensis respiratory tract infection
-
Pyles RB, Jezek GE, Eaves-Pyles TD. Toll-like receptor 3 agonist protection against experimental Francisella tularensis respiratory tract infection. Infect. Immun. 78(4), 1700-1710 (2010).
-
(2010)
Infect. Immun.
, vol.78
, Issue.4
, pp. 1700-1710
-
-
Pyles, R.B.1
Jezek, G.E.2
Eaves-Pyles, T.D.3
-
103
-
-
80054122543
-
Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice
-
Lippmann J, Muller HC, Naujoks J et al. Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice. Cell. Microbiol. 13(11), 1668-1682 (2011).
-
(2011)
Cell. Microbiol.
, vol.13
, Issue.11
, pp. 1668-1682
-
-
Lippmann, J.1
Muller, H.C.2
Naujoks, J.3
-
104
-
-
78649883780
-
IFN regulatory factor 3 contributes to the host response during Pseudomonas aeruginosa lung infection in mice
-
Carrigan SO, Junkins R, Yang YJ et al. IFN regulatory factor 3 contributes to the host response during Pseudomonas aeruginosa lung infection in mice. J. Immunol. 185(6), 3602-3609 (2010).
-
(2010)
J. Immunol.
, vol.185
, Issue.6
, pp. 3602-3609
-
-
Carrigan, S.O.1
Junkins, R.2
Yang, Y.J.3
-
105
-
-
77951782290
-
Intranasal poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population
-
Antonelli LR, Gigliotti Rothfuchs A, Goncalves R et al. Intranasal poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population. J. Clin. Invest. 120(5), 1674-1682 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, Issue.5
, pp. 1674-1682
-
-
Antonelli, L.R.1
Gigliotti Rothfuchs, A.2
Goncalves, R.3
-
106
-
-
84866043645
-
Poly I:C enhances susceptibility to secondary pulmonary infections by Gram-positive bacteria
-
Tian X, Xu F, Lung WY et al. Poly I:C enhances susceptibility to secondary pulmonary infections by Gram-positive bacteria. PLoS ONE 7(9), e41879 (2012).
-
(2012)
PLoS One
, vol.7
, Issue.9
-
-
Tian, X.1
Xu, F.2
Lung, W.Y.3
-
107
-
-
84859405717
-
Signaling by myeloid C-type lectin receptors in immunity and homeostasis
-
Sancho D, Reis e Sousa C. Signaling by myeloid C-type lectin receptors in immunity and homeostasis. Annu. Rev. Immunol. 30, 491-529 (2012).
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 491-529
-
-
Sancho, D.1
Reise Sousa, C.2
-
108
-
-
77951932177
-
Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate
-
Schoenen H, Bodendorfer B, Hitchens K et al. Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate. J. Immunol. 184(6), 2756-2760 (2010).
-
(2010)
J. Immunol.
, vol.184
, Issue.6
, pp. 2756-2760
-
-
Schoenen, H.1
Bodendorfer, B.2
Hitchens, K.3
-
109
-
-
73949117849
-
Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle
-
Ishikawa E, Ishikawa T, Morita YS et al. Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle. J. Exp. Med. 206(13), 2879-2888 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, Issue.13
, pp. 2879-2888
-
-
Ishikawa, E.1
Ishikawa, T.2
Morita, Y.S.3
-
110
-
-
80053255932
-
Targeting Syk-Card9-activating C-type lectin receptors by vaccine adjuvants: Findings, implications and open questions
-
Lang R. Schoenen H.Desel C. Targeting Syk-Card9-activating C-type lectin receptors by vaccine adjuvants: Findings, implications and open questions Immunobiology 2011 26:11 1184-1191.
-
(2011)
Immunobiology
, vol.216
, Issue.11
, pp. 1184-1191
-
-
Lang, R.1
Schoenen, H.2
Desel, C.3
-
111
-
-
84865411904
-
C-type lectin receptors orchestrate antifungal immunity
-
Lang R, Schoenen H, Desel C. Targeting Syk-Card9-activating C-type lectin receptors by vaccine adjuvants: Findings, implications and open questions. Immunobiology 216(11), 1184-1191 (2011). 111 Hardison SE, Brown GD. C-type lectin receptors orchestrate antifungal immunity. Nat. Immunol. 13(9), 817-822 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, Issue.9
, pp. 817-822
-
-
Hardison, S.E.1
Brown, G.D.2
-
112
-
-
84869479505
-
Innate sensing of bacterial cyclic dinucleotides: More than just STING
-
Bowie AG. Innate sensing of bacterial cyclic dinucleotides: More than just STING. Nat. Immunol. 13(12), 1137-1139 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, Issue.12
, pp. 1137-1139
-
-
Bowie, A.G.1
-
113
-
-
33846916451
-
Bacterial c-di-GMP is an immunostimulatory molecule
-
Karaolis DK, Means TK, Yang D et al. Bacterial c-di-GMP is an immunostimulatory molecule. J. Immunol. 178(4), 2171-2181 (2007).
-
(2007)
J. Immunol.
, vol.178
, Issue.4
, pp. 2171-2181
-
-
Karaolis, D.K.1
Means, T.K.2
Yang, D.3
-
114
-
-
34848901383
-
Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia
-
First demonstration of the immunostimulatory potential of bacterial second messenger molecule c-di-GMP. 114 Karaolis DK, Newstead MW, Zeng X et al. Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia. Infect. Immun. 75(10), 4942-4950 (2007).
-
(2007)
Infect. Immun.
, vol.75
, Issue.10
, pp. 4942-4950
-
-
Karaolis, D.K.1
Newstead, M.W.2
Zeng, X.3
-
115
-
-
48649084066
-
C-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection
-
Ogunniyi AD, Paton JC, Kirby AC et al. c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection. Vaccine 26(36), 4676-4685 (2008).
-
(2008)
Vaccine
, vol.26
, Issue.36
, pp. 4676-4685
-
-
Ogunniyi, A.D.1
Paton, J.C.2
Kirby, A.C.3
-
116
-
-
80051864478
-
C-di-GMP protects against intranasal Acinetobacter baumannii infection in mice by chemokine induction and enhanced neutrophil recruitment
-
Zhao L, Kuolee R, Harris G, Tram K, Yan H, Chen W. c-di-GMP protects against intranasal Acinetobacter baumannii infection in mice by chemokine induction and enhanced neutrophil recruitment. Int. Immunopharmacol. 11(9), 1378-1383 (2011).
-
(2011)
Int. Immunopharmacol.
, vol.11
, Issue.9
, pp. 1378-1383
-
-
Zhao, L.1
Kuolee, R.2
Harris, G.3
Tram, K.4
Yan, H.5
Chen, W.6
-
117
-
-
79960291542
-
Bis-(3́,5́)-cyclic dimeric adenosine monophosphate: Strong Th1/Th2/Th17 promoting mucosal adjuvant
-
Ebensen T, Libanova R, Schulze K, Yevsa T, Morr M, Guzman CA. Bis-(3́,5́)-cyclic dimeric adenosine monophosphate: Strong Th1/Th2/Th17 promoting mucosal adjuvant. Vaccine 29(32), 5210-5220 (2011).
-
(2011)
Vaccine
, vol.29
, Issue.32
, pp. 5210-5220
-
-
Ebensen, T.1
Libanova, R.2
Schulze, K.3
Yevsa, T.4
Morr, M.5
Guzman, C.A.6
-
118
-
-
84868270751
-
Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities
-
Gray PM, Forrest G, Wisniewski T et al. Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities. Cell Immunol. 278(1-2), 113-119 (2012).
-
(2012)
Cell Immunol.
, vol.278
, Issue.1-2
, pp. 113-119
-
-
Gray, P.M.1
Forrest, G.2
Wisniewski, T.3
-
119
-
-
79959792793
-
Intranasal c-di-GMP-adjuvanted plantderived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice
-
Madhun AS, Haaheim LR, Nostbakken JK et al. Intranasal c-di-GMP-adjuvanted plantderived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice. Vaccine 29(31), 4973-4982 (2011).
-
(2011)
Vaccine
, vol.29
, Issue.31
, pp. 4973-4982
-
-
Madhun, A.S.1
Haaheim, L.R.2
Nostbakken, J.K.3
-
120
-
-
84857207302
-
Cyclic di-nucleotides: New era for small molecules as adjuvants
-
Libanova R, Becker PD, Guzman CA. Cyclic di-nucleotides: New era for small molecules as adjuvants. Microb. Biotechnol. 5(2), 168-176 (2012).
-
(2012)
Microb. Biotechnol.
, vol.5
, Issue.2
, pp. 168-176
-
-
Libanova, R.1
Becker, P.D.2
Guzman, C.A.3
-
121
-
-
84873724533
-
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
-
Wu J, Sun L, Chen X et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339(6121), 826-830 (2012).
-
(2012)
Science
, vol.339
, Issue.6121
, pp. 826-830
-
-
Wu, J.1
Sun, L.2
Chen, X.3
-
122
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
-
Sun L, Wu J, Du F, Chen X, Chen ZJ. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339(6121), 786-791 (2012).
-
(2012)
Science
, vol.339
, Issue.6121
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
123
-
-
0141780934
-
The Pseudomonas aeruginosa autoinducer N-3- oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils
-
Tateda K, Ishii Y, Horikawa M et al. The Pseudomonas aeruginosa autoinducer N-3- oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils. Infect. Immun. 71(10), 5785-5793 (2003).
-
(2003)
Infect. Immun.
, vol.71
, Issue.10
, pp. 5785-5793
-
-
Tateda, K.1
Ishii, Y.2
Horikawa, M.3
-
124
-
-
84855325747
-
N-acylhomoserine lactones are potent neutrophil chemoattractants that act via calcium mobilization and actin remodeling
-
Karlsson T, Musse F, Magnusson KE, Vikstrom E. N-acylhomoserine lactones are potent neutrophil chemoattractants that act via calcium mobilization and actin remodeling. J. Leukoc. Biol. 91(1), 15-26 (2012).
-
(2012)
J. Leukoc. Biol.
, vol.91
, Issue.1
, pp. 15-26
-
-
Karlsson, T.1
Musse, F.2
Magnusson, K.E.3
Vikstrom, E.4
-
125
-
-
84868610108
-
T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection
-
Lee RJ, Xiong G, Kofonow JM et al. T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. J. Clin. Invest. 122(11), 4145-4159 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, Issue.11
, pp. 4145-4159
-
-
Lee, R.J.1
Xiong, G.2
Kofonow, J.M.3
-
126
-
-
79959450318
-
Immunomodulatory and protective roles of quorum-sensing signaling molecules N-acyl homoserine lactones during infection of mice with Aeromonas hydrophila
-
Khajanchi BK, Kirtley ML, Brackman SM, Chopra AK. Immunomodulatory and protective roles of quorum-sensing signaling molecules N-acyl homoserine lactones during infection of mice with Aeromonas hydrophila. Infect. Immun. 79(7), 2646-2657 (2011).
-
(2011)
Infect. Immun.
, vol.79
, Issue.7
, pp. 2646-2657
-
-
Khajanchi, B.K.1
Kirtley, M.L.2
Brackman, S.M.3
Chopra, A.K.4
-
128
-
-
79953839924
-
Quenching the quorum sensing system: Potential antibacterial drug targets
-
Kalia VC, Purohit HJ. Quenching the quorum sensing system: Potential antibacterial drug targets. Crit. Rev. Microbiol. 37(2), 121-140 (2011).
-
(2011)
Crit. Rev. Microbiol.
, vol.37
, Issue.2
, pp. 121-140
-
-
Kalia, V.C.1
Purohit, H.J.2
-
129
-
-
0348230962
-
Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections
-
Hentzer M, Givskov M. Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J. Clin. Invest. 112(9), 1300-1307 (2003).
-
(2003)
J. Clin. Invest.
, vol.112
, Issue.9
, pp. 1300-1307
-
-
Hentzer, M.1
Givskov, M.2
-
130
-
-
0041989633
-
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors
-
Hentzer M, Wu H, Andersen JB et al. Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 22(15), 3803-3815 (2003).
-
(2003)
EMBO J.
, vol.22
, Issue.15
, pp. 3803-3815
-
-
Hentzer, M.1
Wu, H.2
Andersen, J.B.3
-
131
-
-
84867770740
-
Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-acyl homoserine lactones
-
Stacy DM, Welsh MA, Rather PN, Blackwell HE. Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-acyl homoserine lactones. ACS Chem. Biol. 7(10), 1719-1728 (2012).
-
(2012)
ACS Chem. Biol.
, vol.7
, Issue.10
, pp. 1719-1728
-
-
Stacy, D.M.1
Welsh, M.A.2
Rather, P.N.3
Blackwell, H.E.4
-
132
-
-
79956311555
-
Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo
-
Brackman G, Cos P, Maes L, Nelis HJ, Coenye T. Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo. Antimicrob. Agents Chemother. 55(6), 2655-2661 (2011).
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, Issue.6
, pp. 2655-2661
-
-
Brackman, G.1
Cos, P.2
Maes, L.3
Nelis, H.J.4
Coenye, T.5
-
133
-
-
3042597309
-
Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice
-
Wu H, Song Z, Hentzer M et al. Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice. J. Antimicrob. Chemother. 53(6), 1054-1061 (2004).
-
(2004)
J. Antimicrob. Chemother.
, vol.53
, Issue.6
, pp. 1054-1061
-
-
Wu, H.1
Song, Z.2
Hentzer, M.3
-
134
-
-
84867073873
-
Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitors
-
Storz MP, Maurer CK, Zimmer C et al. Validation of PqsD as an anti-biofilm target in Pseudomonas aeruginosa by development of small-molecule inhibitors. J. Am. Chem. Soc. 134(39), 16143-16146 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, Issue.39
, pp. 16143-16146
-
-
Storz, M.P.1
Maurer, C.K.2
Zimmer, C.3
-
135
-
-
79952353193
-
Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: Co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia
-
Chan KG, Atkinson S, Mathee K et al. Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: Co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia. BMC Microbiol. 11, 51 (2011).
-
(2011)
BMC Microbiol.
, vol.11
, Issue.51
-
-
Chan, K.G.1
Atkinson, S.2
Mathee, K.3
-
136
-
-
84857866008
-
Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin
-
Stout-Delgado HW, Vaughan SE, Shirali AC, Jaramillo RJ, Harrod KS. Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin. J. Immunol. 188(6), 2815-2824 (2012).
-
(2012)
J. Immunol.
, vol.188
, Issue.6
, pp. 2815-2824
-
-
Stout-Delgado, H.W.1
Vaughan, S.E.2
Shirali, A.C.3
Jaramillo, R.J.4
Harrod, K.S.5
-
137
-
-
84855954988
-
NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8(+) T cells
-
Kupz A, Guarda G, Gebhardt T et al. NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8(+) T cells. Nat. Immunol. 13(2), 162-169 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, Issue.2
, pp. 162-169
-
-
Kupz, A.1
Guarda, G.2
Gebhardt, T.3
-
138
-
-
78649903057
-
Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity
-
Mcmahan RH, Golden-Mason L, Nishimura MI et al. Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity. J. Clin. Invest. 120(12), 4546-4557 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, Issue.12
, pp. 4546-4557
-
-
Mcmahan, R.H.1
Golden-Mason, L.2
Nishimura, M.I.3
-
139
-
-
62249172189
-
Enhancing SIV-specific immunity in vivo by PD-1 blockade
-
Velu V, Titanji K, Zhu B et al. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 458(7235), 206-210 (2009).
-
(2009)
Nature
, vol.458
, Issue.7235
, pp. 206-210
-
-
Velu, V.1
Titanji, K.2
Zhu, B.3
-
140
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366(26), 2443-2454 (2012).
-
(2012)
N. Engl. J. Med.
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
141
-
-
46749136412
-
When signaling pathways collide: Positive and negative regulation of Toll-like receptor signal transduction
-
O'Neill LA. When signaling pathways collide: Positive and negative regulation of Toll-like receptor signal transduction. Immunity 29(1), 12-20 (2008).
-
(2008)
Immunity
, vol.29
, Issue.1
, pp. 12-20
-
-
O'Neill, L.A.1
-
142
-
-
34648827051
-
Microbial immune evasion employing suppressor of cytokine signaling (SOCS) proteins
-
Baetz A, Zimmermann S, Dalpke AH. Microbial immune evasion employing suppressor of cytokine signaling (SOCS) proteins. Inflamm. Allergy Drug Targets 6(3), 160-167 (2007).
-
(2007)
Inflamm. Allergy Drug Targets
, vol.6
, Issue.3
, pp. 160-167
-
-
Baetz, A.1
Zimmermann, S.2
Dalpke, A.H.3
-
143
-
-
57149092384
-
Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression
-
Pauli EK, Schmolke M, Wolff T et al. Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression. PLoS Pathog. 4(11), e1000196 (2008).
-
(2008)
PLoS Pathog.
, vol.4
, Issue.11
-
-
Pauli, E.K.1
Schmolke, M.2
Wolff, T.3
-
144
-
-
57349153494
-
A Phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: A North American Brain Tumor Consortium (NABTC01-05)
-
Butowski N, Chang SM, Junck L et al. A Phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: A North American Brain Tumor Consortium (NABTC01-05). J. Neurooncol. 91(2), 175-182 (2009).
-
(2009)
J. Neurooncol.
, vol.91
, Issue.2
, pp. 175-182
-
-
Butowski, N.1
Chang, S.M.2
Junck, L.3
-
145
-
-
80052305941
-
The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection
-
Romero CD, Varma TK, Hobbs JB, Reyes A, Driver B, Sherwood ER. The Toll-like receptor 4 agonist monophosphoryl lipid a augments innate host resistance to systemic bacterial infection. Infect. Immun. 79(9), 3576-3587 (2011).
-
(2011)
Infect. Immun.
, vol.79
, Issue.9
, pp. 3576-3587
-
-
Romero, C.D.1
Varma, T.K.2
Hobbs, J.B.3
Reyes, A.4
Driver, B.5
Sherwood, E.R.6
-
146
-
-
79954582124
-
TLR-based immune adjuvants
-
Steinhagen F, Kinjo T, Bode C, Klinman DM. TLR-based immune adjuvants. Vaccine 29(17), 3341-3355 (2011).
-
(2011)
Vaccine
, vol.29
, Issue.17
, pp. 3341-3355
-
-
Steinhagen, F.1
Kinjo, T.2
Bode, C.3
Klinman, D.M.4
-
147
-
-
48549085489
-
Flagellin treatment protects against chemicals, bacteria, viruses, and radiation
-
Vijay-Kumar M, Aitken JD, Sanders CJ et al. Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. J. Immunol. 180(12), 8280-8285 (2008).
-
(2008)
J. Immunol.
, vol.180
, Issue.12
, pp. 8280-8285
-
-
Vijay-Kumar, M.1
Aitken, J.D.2
Sanders, C.J.3
-
148
-
-
75749133608
-
Bacterial flagellin stimulates Toll-like receptor 5-dependent defense against vancomycinresistant Enterococcus infection
-
Kinnebrew MA, Ubeda C, Zenewicz LA, Smith N, Flavell RA, Pamer EG. Bacterial flagellin stimulates Toll-like receptor 5-dependent defense against vancomycinresistant Enterococcus infection. J. Infect. Dis. 201(4), 534-543 (2010).
-
(2010)
J. Infect. Dis.
, vol.201
, Issue.4
, pp. 534-543
-
-
Kinnebrew, M.A.1
Ubeda, C.2
Zenewicz, L.A.3
Smith, N.4
Flavell, R.A.5
Pamer, E.G.6
-
149
-
-
79953300500
-
Toll-like receptor 5 stimulation protects mice from acute Clostridium difficile colitis
-
Jarchum I, Liu M, Lipuma L, Pamer EG. Toll-like receptor 5 stimulation protects mice from acute Clostridium difficile colitis. Infect. Immun. 79(4), 1498-1503 (2011).
-
(2011)
Infect. Immun.
, vol.79
, Issue.4
, pp. 1498-1503
-
-
Jarchum, I.1
Liu, M.2
Lipuma, L.3
Pamer, E.G.4
-
150
-
-
84864945063
-
Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response
-
Taylor DN, Treanor JJ, Sheldon EA et al. Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response. Vaccine 30(39), 5761-5769 (2012).
-
(2012)
Vaccine
, vol.30
, Issue.39
, pp. 5761-5769
-
-
Taylor, D.N.1
Treanor, J.J.2
Sheldon, E.A.3
-
151
-
-
78650827526
-
Immunopotentiation of trivalent influenza vaccine when given with VAX102, a recombinant influenza M2e vaccine fused to the TLR5 ligand flagellin
-
Talbot HK, Rock MT, Johnson C et al. Immunopotentiation of trivalent influenza vaccine when given with VAX102, a recombinant influenza M2e vaccine fused to the TLR5 ligand flagellin. PLoS ONE 5(12), e14442 (2010).
-
(2010)
PLoS ONE
, vol.5
, Issue.12
-
-
Talbot, H.K.1
Rock, M.T.2
Johnson, C.3
-
152
-
-
80755163546
-
Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway
-
Boyer L, Magoc L, Dejardin S et al. Pathogen-derived effectors trigger protective immunity via activation of the Rac2 enzyme and the IMD or Rip kinase signaling pathway. Immunity 35(4), 536-549 (2011).
-
(2011)
Immunity
, vol.35
, Issue.4
, pp. 536-549
-
-
Boyer, L.1
Magoc, L.2
Dejardin, S.3
-
153
-
-
23044502258
-
3́,5́-cyclic diguanylic acid reduces the virulence of biofilm-forming Staphylococcus aureus strains in a mouse model of mastitis infection
-
Brouillette E, Hyodo M, Hayakawa Y, Karaolis DK, Malouin F. 3́,5́-cyclic diguanylic acid reduces the virulence of biofilm-forming Staphylococcus aureus strains in a mouse model of mastitis infection. Antimicrob. Agents Chemother. 49(8), 3109-3113 (2005).
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, Issue.8
, pp. 3109-3113
-
-
Brouillette, E.1
Hyodo, M.2
Hayakawa, Y.3
Karaolis, D.K.4
Malouin, F.5
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