Administration of a synthetic TLR4 agonist protects mice from pneumonic tularemia

Journal of Immunology

Volumn 180, Issue 11, 2008, Pages 7574-7581

  Lembo, Annalisa ^a   Pelletier, Mark ^a   Iyer, Ravi ^a   Timko, Michele ^a   Dudda, Jan C ^b   West, T Eoin ^a   Wilson, Christopher B ^a   Hajjar, Adeline M ^a   Skerrett, Shawn J ^a,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b BENAROYA RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOALKYL GLUCOSAMINIDE PHOSPHATE; CHEMOKINE; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN G2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 4 AGONIST; TOLL LIKE RECEPTOR AGONIST; UNCLASSIFIED DRUG; AGP 524; AGP 527; DRUG DERIVATIVE; GLUCOSAMINE; ORGANOPHOSPHORUS COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FRANCISELLA; INNATE IMMUNITY; LIVER; LUNG PARENCHYMA; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; SPLEEN CELL; SURVIVAL TIME; TH1 CELL; TULAREMIA; ANIMAL; BACTERIAL PNEUMONIA; BIOSYNTHESIS; C57BL MOUSE; CELL LINE; DENDRITIC CELL; DRUG POTENTIATION; FRANCISELLA TULARENSIS; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; INTRANASAL DRUG ADMINISTRATION; LUNG; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; METABOLISM; MICROBIOLOGY; MOUSE MUTANT;

ADMINISTRATION, INTRANASAL; ANIMALS; BRONCHOALVEOLAR LAVAGE; CELL LINE; CYTOKINES; DENDRITIC CELLS; FRANCISELLA TULARENSIS; GLUCOSAMINE; IMMUNITY, NATURAL; INTERFERON TYPE II; LIVER; LUNG; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; ORGANOPHOSPHORUS COMPOUNDS; PNEUMONIA, BACTERIAL; SPLEEN; TOLL-LIKE RECEPTOR 4; TULAREMIA;

EID: 45849140258     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.11.7574     Document Type: Article

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