Cyclic di-GMP stimulates protective innate immunity in bacterial pneumonia

Infection and Immunity

Volumn 75, Issue 10, 2007, Pages 4942-4950

  Karaolis, David K R ^a,b   Newstead, Michael W ^c   Zeng, Xianying ^c   Hyodo, Mamoru ^d   Hayakawa, Yoshihiro ^d   Bhan, Urvhashi ^c   Liang, Hallie ^c   Standiford, Theodore J ^c  

^a Intragenics Research Institute   (United States)

^b Karagen Pharmaceuticals   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYCLIC DIGUANYLATE; CYCLIC GMP; CYTOKINE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL PNEUMONIA; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNE RESPONSE; INFECTION PREVENTION; INNATE IMMUNITY; KLEBSIELLA PNEUMONIAE; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

ADMINISTRATION, INTRANASAL; ANIMALS; BLOOD; CHEMOKINES; COLONY COUNT, MICROBIAL; CYCLIC GMP; CYTOKINES; FEMALE; IMMUNITY, NATURAL; IMMUNOLOGIC FACTORS; INJECTIONS, SUBCUTANEOUS; KILLER CELLS, NATURAL; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LUNG; MACROPHAGES, ALVEOLAR; MICE; MICE, INBRED BALB C; NEUTROPHILS; NITRIC OXIDE; PNEUMONIA, BACTERIAL; SPECIFIC PATHOGEN-FREE ORGANISMS; SURVIVAL ANALYSIS; T-LYMPHOCYTES;

EID: 34848901383     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01762-06     Document Type: Article

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