Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections

Journal of Clinical Investigation

Volumn 112, Issue 9, 2003, Pages 1300-1307

  Hentzer, Morten ^a   Givskov, Michael ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AHL DEGRADING ENZYME; ANTIINFECTIVE AGENT; C 30; ENZYME; ERYTHROMYCIN; FUNGAL PROTEIN; FURANONE DERIVATIVE; HALOGENATED FURANONE DERIVATIVE; HOMOSERINE; HOMOSERINE LACTONE DERIVATIVE; LACTONE; LUXI PROTEIN; MACROLIDE; N ACYLHOMOSERINE LACTONE; PIPERACILLIN; PLANT EXTRACT; PROTEIN; QUORUM SENSING INHIBITOR; S ADENOSYLCYSTEINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; S ADENOSYLMETHIONINE DERIVATIVE; SINEFUNGIN; TOBRAMYCIN; TRANSCRIPTION FACTOR LUXR; UNCLASSIFIED DRUG;

AHL MEDIATED QUORUM SENSING SYSTEM; ANTIMICROBIAL THERAPY; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIAL VIRULENCE; BIOFILM; CHRONIC BACTERIAL INFECTION; DRUG EFFECT; DRUG MECHANISM; DRUG SCREENING; GRAM NEGATIVE BACTERIUM; GROWTH INHIBITION; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; QUORUM SENSING; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION;

EID: 0348230962     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI20074     Document Type: Review

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