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Volumn 33, Issue 1, 2013, Pages 41-56

Homeostatic regulation of aging and rejuvenation in the B lineage cells

Author keywords

Aging; B lymphocyte; Hematopoietic stem cells; Immune system; Rejuvenation

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; B LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 84875076234     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: 10.1615/CritRevImmunol.2013006907     Document Type: Article
Times cited : (5)

References (118)
  • 1
    • 0030619342 scopus 로고    scopus 로고
    • Doubling of world population unlikely
    • Lutz W, Sanderson W, Scherbov S. Doubling of world population unlikely. Nature. 1997;387:803-5.
    • (1997) Nature. , vol.387 , pp. 803-805
    • Lutz, W.1    Sanderson, W.2    Scherbov, S.3
  • 3
    • 70350504881 scopus 로고    scopus 로고
    • Epidemiology and consequences of sarcopenia
    • Abellan van Kan G. Epidemiology and consequences of sarcopenia. J Nutr Health Aging. 2009;13:708-12.
    • (2009) J Nutr Health Aging. , vol.13 , pp. 708-712
    • van Abellan Kan, G.1
  • 4
    • 4444320808 scopus 로고    scopus 로고
    • Ageing, autoimmunity and arthritis: Senescence of the B cell compartment-implications for humoral immunity
    • Johnson SA, Cambier JC. Ageing, autoimmunity and arthritis: senescence of the B cell compartment-implications for humoral immunity. Arthritis Res Ther. 2004;6:131-9.
    • (2004) Arthritis Res Ther. , vol.6 , pp. 131-139
    • Johnson, S.A.1    Cambier, J.C.2
  • 5
    • 1142275269 scopus 로고    scopus 로고
    • Age-related changes in lymphocyte development and function
    • Linton PJ, Dorshkind K. Age-related changes in lymphocyte development and function. Nat Immunol. 2004;5:133-9.
    • (2004) Nat Immunol. , vol.5 , pp. 133-139
    • Linton, P.J.1    Dorshkind, K.2
  • 6
    • 46249132015 scopus 로고    scopus 로고
    • Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections
    • Nikolich-Zugich J. Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections. Nat Rev Immunol. 2008;8:512-22.
    • (2008) Nat Rev Immunol. , vol.8 , pp. 512-522
    • Nikolich-Zugich, J.1
  • 7
    • 33646546302 scopus 로고    scopus 로고
    • Aging of the immune system: How much can the adaptive immune system adapt?
    • Weng NP. Aging of the immune system: how much can the adaptive immune system adapt? Immunity. 2006;24:495-9.
    • (2006) Immunity. , vol.24 , pp. 495-499
    • Weng, N.P.1
  • 8
    • 45949103917 scopus 로고    scopus 로고
    • Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells
    • Frasca D, Landin AM, Lechner SC, Ryan JG, Schwartz R, Riley RL, Blomberg BB. Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells. J Immunol. 2008;180:5283-90.
    • (2008) J Immunol. , vol.180 , pp. 5283-5290
    • Frasca, D.1    Landin, A.M.2    Lechner, S.C.3    Ryan, J.G.4    Schwartz, R.5    Riley, R.L.6    Blomberg, B.B.7
  • 10
    • 41149170727 scopus 로고    scopus 로고
    • Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus
    • Yager EJ, Ahmed M, Lanzer K, Randall TD, Woodland DL, Blackman MA. Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J Exp Med. 2008;205:711-23.
    • (2008) J Exp Med. , vol.205 , pp. 711-723
    • Yager, E.J.1    Ahmed, M.2    Lanzer, K.3    Randall, T.D.4    Woodland, D.L.5    Blackman, M.A.6
  • 11
    • 0037094083 scopus 로고    scopus 로고
    • Agingdependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire
    • Johnson SA, Rozzo SJ, Cambier JC. Agingdependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire. J Immunol. 2002;168:5014-23.
    • (2002) J Immunol. , vol.168 , pp. 5014-5023
    • Johnson, S.A.1    Rozzo, S.J.2    Cambier, J.C.3
  • 12
    • 0033559509 scopus 로고    scopus 로고
    • B cell maintenance in aged mice reflects both increased B cell longevity and decreased B cell generation
    • Kline GH, Hayden TA, Klinman NR. B cell maintenance in aged mice reflects both increased B cell longevity and decreased B cell generation. J Immunol. 1999;162:3342-9.
    • (1999) J Immunol. , vol.162 , pp. 3342-3349
    • Kline, G.H.1    Hayden, T.A.2    Klinman, N.R.3
  • 14
    • 67649402297 scopus 로고    scopus 로고
    • Aging in the lymphohematopoietic stem cell compartment
    • Geiger H, Rudolph KL. Aging in the lymphohematopoietic stem cell compartment. Trends in Immunology. 2009;30:360-65.
    • (2009) Trends in Immunology. , vol.30 , pp. 360-365
    • Geiger, H.1    Rudolph, K.L.2
  • 16
    • 65649118112 scopus 로고    scopus 로고
    • Prevention of infectious diseases in older adults through immunization: The challenge of the senescent immune response
    • McElhaney JE. Prevention of infectious diseases in older adults through immunization: the challenge of the senescent immune response. Expert RevVacc. 2009;8:593-606.
    • (2009) Expert RevVacc. , vol.8 , pp. 593-606
    • McElhaney, J.E.1
  • 18
    • 77950070632 scopus 로고    scopus 로고
    • Effector and regulatory B cells: Modulators of CD4+ T cell immunity
    • Lund FE, Randall TD. Effector and regulatory B cells: modulators of CD4+ T cell immunity. Nat Rev Immunol. 2010;10:236-47.
    • (2010) Nat Rev Immunol. , vol.10 , pp. 236-247
    • Lund, F.E.1    Randall, T.D.2
  • 19
    • 84861724649 scopus 로고    scopus 로고
    • Human CD19+CD25high B regulatory cells suppress proliferation of CD4+ T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells
    • Kessel A, Haj T, Peri R, Snir A, Melamed D, Sabo E, Toubi E. Human CD19+CD25high B regulatory cells suppress proliferation of CD4+ T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells. Autoimmunity Reviews. 2012;11:670-77.
    • (2012) Autoimmunity Reviews. , vol.11 , pp. 670-677
    • Kessel, A.1    Haj, T.2    Peri, R.3    Snir, A.4    Melamed, D.5    Sabo, E.6    Toubi, E.7
  • 20
    • 0030741166 scopus 로고    scopus 로고
    • Production of cytokines by human B cells in health and disease
    • Pistoia V. Production of cytokines by human B cells in health and disease. Immunol Today. 1997;18:343-50.
    • (1997) Immunol Today. , vol.18 , pp. 343-350
    • Pistoia, V.1
  • 23
    • 84869798045 scopus 로고    scopus 로고
    • Aging and neoteny in the B lineage
    • Melamed D, Scott DW. Aging and neoteny in the B lineage. Blood. 2012;120:4143-49.
    • (2012) Blood. , vol.120 , pp. 4143-4149
    • Melamed, D.1    Scott, D.W.2
  • 24
    • 0025868702 scopus 로고
    • Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
    • Hardy RR, Carmack CE, Shinton SA, Kemp JD, Hayakawa K. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow. J Exp Med. 1991;173:1213-25.
    • (1991) J Exp Med. , vol.173 , pp. 1213-1225
    • Hardy, R.R.1    Carmack, C.E.2    Shinton, S.A.3    Kemp, J.D.4    Hayakawa, K.5
  • 26
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • Rajewsky K. Clonal selection and learning in the antibody system. Nature. 1996;381:751-58.
    • (1996) Nature. , vol.381 , pp. 751-758
    • Rajewsky, K.1
  • 27
    • 4644229948 scopus 로고    scopus 로고
    • Receptor editing in positive and negative selection of B lymphopoiesis
    • Edry E, Melamed D. Receptor editing in positive and negative selection of B lymphopoiesis. J Immunol. 2004;173:4265-71.
    • (2004) J Immunol. , vol.173 , pp. 4265-4271
    • Edry, E.1    Melamed, D.2
  • 29
    • 33645310982 scopus 로고    scopus 로고
    • ITAM-mediated tonic signalling through pre-BCR and BCR complexes
    • Monroe JG. ITAM-mediated tonic signalling through pre-BCR and BCR complexes. Nat Rev Immunol. 2006;6:283-94.
    • (2006) Nat Rev Immunol. , vol.6 , pp. 283-294
    • Monroe, J.G.1
  • 30
    • 0036212917 scopus 로고    scopus 로고
    • Molecular mechanism of class switch recombination: Linkage with somatic hypermutation
    • Honjo T, Kinoshita K, Muramatsu M. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu Rev Immunol. 2002;20:165-96.
    • (2002) Annu Rev Immunol. , vol.20 , pp. 165-196
    • Honjo, T.1    Kinoshita, K.2    Muramatsu, M.3
  • 33
    • 84855241585 scopus 로고    scopus 로고
    • BAFF-R expression correlates with positive selection of immature B cells
    • Tussiwand R, Rauch M, Flück LA, Rolink AG. BAFF-R expression correlates with positive selection of immature B cells. Eur J Immunol. 2012;42:206-16.
    • (2012) Eur J Immunol. , vol.42 , pp. 206-216
    • Tussiwand, R.1    Rauch, M.2    Flück, L.A.3    Rolink, A.G.4
  • 34
    • 0029550111 scopus 로고
    • Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate
    • Cyster JG, Goodnow CC. Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate. Immunity. 1995;3:691-701.
    • (1995) Immunity. , vol.3 , pp. 691-701
    • Cyster, J.G.1    Goodnow, C.C.2
  • 36
    • 0025801026 scopus 로고
    • Proliferation kinetics and the lifespan of B cells in central and peripheral lymphoid organs
    • Osmond DG. Proliferation kinetics and the lifespan of B cells in central and peripheral lymphoid organs. Curr Opin Immunol. 1991;3:179-85.
    • (1991) Curr Opin Immunol. , vol.3 , pp. 179-185
    • Osmond, D.G.1
  • 37
    • 0035887189 scopus 로고    scopus 로고
    • Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow
    • Hao Z, Rajewsky K. Homeostasis of peripheral B cells in the absence of B cell influx from the bone marrow. J Exp Med. 2001;194:1151-64.
    • (2001) J Exp Med. , vol.194 , pp. 1151-1164
    • Hao, Z.1    Rajewsky, K.2
  • 39
    • 0019343926 scopus 로고
    • Regulation and localization of lymphocyte production in the bone marrow
    • Osmond DG, Fahlman MT, Fulop GM, Rahal DM. Regulation and localization of lymphocyte production in the bone marrow. Ciba Found Symp. 1981;84:68-86.
    • (1981) Ciba Found Symp. , vol.84 , pp. 68-86
    • Osmond, D.G.1    Fahlman, M.T.2    Fulop, G.M.3    Rahal, D.M.4
  • 40
    • 0024547713 scopus 로고
    • Post-irradiation regeneration of early B-lymphocyte precursor cells in mouse bone marrow
    • Park YH, Osmond DG. Post-irradiation regeneration of early B-lymphocyte precursor cells in mouse bone marrow. Immunology. 1989;66:343-7.
    • (1989) Immunology. , vol.66 , pp. 343-347
    • Park, Y.H.1    Osmond, D.G.2
  • 42
    • 0030769486 scopus 로고    scopus 로고
    • Independent homeostatic regulation of B cell compartments
    • Agenes F, Rosado MM, Freitas AA. Independent homeostatic regulation of B cell compartments. Eur J Immunol. 1997;27:1801-7.
    • (1997) Eur J Immunol. , vol.27 , pp. 1801-1807
    • Agenes, F.1    Rosado, M.M.2    Freitas, A.A.3
  • 43
    • 0042931219 scopus 로고    scopus 로고
    • The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors
    • Miller JP, Allman D. The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors. J Immunol. 2003;171:2326-30.
    • (2003) J Immunol. , vol.171 , pp. 2326-2330
    • Miller, J.P.1    Allman, D.2
  • 44
    • 0033962638 scopus 로고    scopus 로고
    • Changes in the B-cell repertoire with age
    • Weksler ME. Changes in the B-cell repertoire with age. Vaccine. 2000;18:1624-8.
    • (2000) Vaccine. , vol.18 , pp. 1624-1628
    • Weksler, M.E.1
  • 45
    • 49149127677 scopus 로고    scopus 로고
    • Mechanisms for decreased function of B cells in aged mice and humans
    • Frasca D, Landin AM, Riley RL, Blomberg BB. Mechanisms for decreased function of B cells in aged mice and humans. J Immunol. 2008;180:2741-6.
    • (2008) J Immunol. , vol.180 , pp. 2741-2746
    • Frasca, D.1    Landin, A.M.2    Riley, R.L.3    Blomberg, B.B.4
  • 49
    • 17644425982 scopus 로고    scopus 로고
    • CD27+ (memory) B cell decrease and apoptosisresistant CD27-(naive) B cell increase in aged humans: Implications for age-related peripheral B cell developmental disturbances
    • Chong Y, Ikematsu H, Yamaji K, Nishimura M, Nabeshima S, Kashiwagi S, Hayashi J. CD27+ (memory) B cell decrease and apoptosisresistant CD27-(naive) B cell increase in aged humans: implications for age-related peripheral B cell developmental disturbances. Int Immunol. 2005;17:383-90.
    • (2005) Int Immunol. , vol.17 , pp. 383-390
    • Chong, Y.1    Ikematsu, H.2    Yamaji, K.3    Nishimura, M.4    Nabeshima, S.5    Kashiwagi, S.6    Hayashi, J.7
  • 51
    • 0036847971 scopus 로고    scopus 로고
    • Aging and developmental transitions in the B cell lineage
    • Johnson KM, Owen K, Witte PL. Aging and developmental transitions in the B cell lineage. Int Immunol. 2002;14:1313-23.
    • (2002) Int Immunol. , vol.14 , pp. 1313-1323
    • Johnson, K.M.1    Owen, K.2    Witte, P.L.3
  • 52
    • 61349097791 scopus 로고    scopus 로고
    • B-cell responses to vaccination at the extremes of age
    • Siegrist CA, Aspinall R. B-cell responses to vaccination at the extremes of age. Nat Rev Immunol. 2009;9:185-94.
    • (2009) Nat Rev Immunol. , vol.9 , pp. 185-194
    • Siegrist, C.A.1    Aspinall, R.2
  • 53
    • 84865603984 scopus 로고    scopus 로고
    • Reversing T cell immunosenescence: Why, who, and how
    • in press Epub ahead of print
    • Lang PO, Govind S, Aspinall R. Reversing T cell immunosenescence: why, who, and how. Age (Dordr). 2012;in press Epub ahead of print.
    • (2012) Age (Dordr)
    • Lang, P.O.1    Govind, S.2    Aspinall, R.3
  • 54
    • 80051568169 scopus 로고    scopus 로고
    • Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c(+) B-cell population is important for the development of autoimmunity
    • Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c(+) B-cell population is important for the development of autoimmunity. Blood. 2011;118:1305-15.
    • (2011) Blood. , vol.118 , pp. 1305-1315
    • Rubtsov, A.V.1    Rubtsova, K.2    Fischer, A.3    Meehan, R.T.4    Gillis, J.Z.5    Kappler, J.W.6    Marrack, P.7
  • 55
    • 80051569441 scopus 로고    scopus 로고
    • A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
    • Hao Y, O'Neill P, Naradikian MS, Scholz JL, Cancro MP. A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood. 2011;118:1294-304.
    • (2011) Blood. , vol.118 , pp. 1294-1304
    • Hao, Y.1    O'Neill, P.2    Naradikian, M.S.3    Scholz, J.L.4    Cancro, M.P.5
  • 57
    • 4043075603 scopus 로고    scopus 로고
    • TNF family member B cell-activating factor (BAFF) receptor-dependent and-independent roles for BAFF in B cell physiology
    • Sasaki Y, Casola S, Kutok JL, Rajewsky K, Schmidt-Supprian M. TNF family member B cell-activating factor (BAFF) receptor-dependent and-independent roles for BAFF in B cell physiology. J Immunol. 2004;173:2245-52.
    • (2004) J Immunol. , vol.173 , pp. 2245-2252
    • Sasaki, Y.1    Casola, S.2    Kutok, J.L.3    Rajewsky, K.4    Schmidt-Supprian, M.5
  • 58
    • 0033854211 scopus 로고    scopus 로고
    • The effect of age on the B-cell repertoire
    • Weksler ME, Szabo P. The effect of age on the B-cell repertoire. J Clin Immunol. 2000;20:240-9.
    • (2000) J Clin Immunol. , vol.20 , pp. 240-249
    • Weksler, M.E.1    Szabo, P.2
  • 60
    • 0031859903 scopus 로고    scopus 로고
    • Altered antibody response to influenza H1N1 vaccine in healthy elderly people as determined by HI, ELISA, and neutralization assay
    • Remarque EJ, de Bruijn IA, Boersma WJ, Masurel N, Ligthart GJ. Altered antibody response to influenza H1N1 vaccine in healthy elderly people as determined by HI, ELISA, and neutralization assay. J Med Virol. 1998;55:82-7.
    • (1998) J Med Virol. , vol.55 , pp. 82-87
    • Remarque, E.J.1    de Bruijn, I.A.2    Boersma, W.J.3    Masurel, N.4    Ligthart, G.J.5
  • 61
    • 32044453088 scopus 로고    scopus 로고
    • Antibody response to influenza vaccination in the elderly: A quantitative review
    • Goodwin K, Viboud C, Simonsen L. Antibody response to influenza vaccination in the elderly: a quantitative review. Vaccine. 2006;24:1159-69.
    • (2006) Vaccine. , vol.24 , pp. 1159-1169
    • Goodwin, K.1    Viboud, C.2    Simonsen, L.3
  • 63
    • 0242349138 scopus 로고    scopus 로고
    • Immunogenicity of combined hepatitis A and B vaccine in elderly persons
    • Wolters B, Junge U, Dziuba S, Roggendorf M. Immunogenicity of combined hepatitis A and B vaccine in elderly persons. Vaccine. 2003;21:3623-28.
    • (2003) Vaccine. , vol.21 , pp. 3623-3628
    • Wolters, B.1    Junge, U.2    Dziuba, S.3    Roggendorf, M.4
  • 66
    • 84863094641 scopus 로고    scopus 로고
    • Agedependent increase of memory B cell response to cytomegalovirus in healthy adults
    • Aberle JH, Puchhammer-Stöckl E. Agedependent increase of memory B cell response to cytomegalovirus in healthy adults. Exper Gerontol. 2012;47:654-7.
    • (2012) Exper Gerontol. , vol.47 , pp. 654-657
    • Aberle, J.H.1    Puchhammer-Stöckl, E.2
  • 68
    • 0035480006 scopus 로고    scopus 로고
    • Human genetic defects in class-switch recombination (hyper-IgM syndromes)
    • Durandy A, Honjo T. Human genetic defects in class-switch recombination (hyper-IgM syndromes). Curr Opin Immunol. 2001;13:543-8.
    • (2001) Curr Opin Immunol. , vol.13 , pp. 543-548
    • Durandy, A.1    Honjo, T.2
  • 70
    • 0027363906 scopus 로고
    • Age-related alterations in the activation and expression of phosphotyrosine kinases and protein kinase C (PKC) among human B cells
    • Whisler RL, Grants IS. Age-related alterations in the activation and expression of phosphotyrosine kinases and protein kinase C (PKC) among human B cells. Mech Ageing Dev. 1993;71:31-46.
    • (1993) Mech Ageing Dev. , vol.71 , pp. 31-46
    • Whisler, R.L.1    Grants, I.S.2
  • 71
    • 0035894941 scopus 로고    scopus 로고
    • B cells of aged mice show decreased expansion in response to antigen, but are normal in effector function
    • Dailey RW, Eun SY, Russell CE, Vogel LA. B cells of aged mice show decreased expansion in response to antigen, but are normal in effector function. Cell Immunol. 2001;214:99-109.
    • (2001) Cell Immunol. , vol.214 , pp. 99-109
    • Dailey, R.W.1    Eun, S.Y.2    Russell, C.E.3    Vogel, L.A.4
  • 72
  • 73
    • 23044456776 scopus 로고    scopus 로고
    • Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans
    • Frasca D, Riley RL, Blomberg BB. Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans. Semin Immunol. 2005;17:378-84.
    • (2005) Semin Immunol. , vol.17 , pp. 378-384
    • Frasca, D.1    Riley, R.L.2    Blomberg, B.B.3
  • 75
    • 0142217362 scopus 로고    scopus 로고
    • Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis
    • Van der Put E, Sherwood EM, Blomberg BB, Riley RL. Aged mice exhibit distinct B cell precursor phenotypes differing in activation, proliferation and apoptosis. Exper Gerontol. 2003;38:1137-47.
    • (2003) Exper Gerontol. , vol.38 , pp. 1137-1147
    • van der Put, E.1    Sherwood, E.M.2    Blomberg, B.B.3    Riley, R.L.4
  • 76
    • 23044497567 scopus 로고    scopus 로고
    • Bone marrow microenvironmental changes in aged mice compromise V(D)J recombinase activity and B cell generation
    • Labrie Iii JE, Borghesi L, Gerstein RM. Bone marrow microenvironmental changes in aged mice compromise V(D)J recombinase activity and B cell generation. Sem Immunol. 2005;17:347-55.
    • (2005) Sem Immunol. , vol.17 , pp. 347-355
    • Labrie Iii, J.E.1    Borghesi, L.2    Gerstein, R.M.3
  • 77
    • 0043022047 scopus 로고    scopus 로고
    • Peripheral B cell selection and homeostasis
    • Cancro MP, Smith SH. Peripheral B cell selection and homeostasis. Immunol Res. 2003;27:141-8.
    • (2003) Immunol Res. , vol.27 , pp. 141-148
    • Cancro, M.P.1    Smith, S.H.2
  • 78
    • 0038206973 scopus 로고    scopus 로고
    • Impaired rearrangement of IgH V to DJ segments in bone marrow Pro-B cells from old mice
    • Szabo P, Shen S, Telford W, Weksler ME. Impaired rearrangement of IgH V to DJ segments in bone marrow Pro-B cells from old mice. Cell Immunol. 2003;222:78-87.
    • (2003) Cell Immunol. , vol.222 , pp. 78-87
    • Szabo, P.1    Shen, S.2    Telford, W.3    Weksler, M.E.4
  • 79
    • 30344455329 scopus 로고    scopus 로고
    • B cell development in aging mice: Lessons from mathematical modeling
    • Shahaf G, Johnson K, Mehr R. B cell development in aging mice: lessons from mathematical modeling. Int Immunol. 2006;18:31-9.
    • (2006) Int Immunol. , vol.18 , pp. 31-39
    • Shahaf, G.1    Johnson, K.2    Mehr, R.3
  • 82
    • 77950418688 scopus 로고    scopus 로고
    • Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
    • Beerman I, Bhattacharya D, Zandi S, Sigvardsson M, Weissman IL, Bryder D, Rossi DJ. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci U S A. 2010;107:5465-70.
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , pp. 5465-5470
    • Beerman, I.1    Bhattacharya, D.2    Zandi, S.3    Sigvardsson, M.4    Weissman, I.L.5    Bryder, D.6    Rossi, D.J.7
  • 83
    • 47049099198 scopus 로고    scopus 로고
    • A new mechanism for the aging of hematopoietic stem cells: Aging changes the clonal composition of the stem cell compartment but not individual stem cells
    • Cho RH, Sieburg HB, Muller-Sieburg CE. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood. 2008;111:5553-61.
    • (2008) Blood. , vol.111 , pp. 5553-5561
    • Cho, R.H.1    Sieburg, H.B.2    Muller-Sieburg, C.E.3
  • 84
    • 50149099346 scopus 로고    scopus 로고
    • Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging
    • Guerrettaz LM, Johnson SA, Cambier JC. Acquired hematopoietic stem cell defects determine B-cell repertoire changes associated with aging. PNAS U S A. 2008;105:11898-902.
    • (2008) PNAS U S A. , vol.105 , pp. 11898-11902
    • Guerrettaz, L.M.1    Johnson, S.A.2    Cambier, J.C.3
  • 85
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi DJ, Bryder D, Seita J, Nussenzweig A, Hoeijmakers J, Weissman IL. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 2007;447:725-9.
    • (2007) Nature. , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 88
    • 77953512588 scopus 로고    scopus 로고
    • Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment
    • Morita Y, Ema H, Nakauchi H. Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment. J Exper Med. 2010;207:1173-82.
    • (2010) J Exper Med. , vol.207 , pp. 1173-1182
    • Morita, Y.1    Ema, H.2    Nakauchi, H.3
  • 92
    • 30744451406 scopus 로고    scopus 로고
    • Effects of aging on the common lymphoid progenitor to pro-B cell transition
    • Min H, Montecino-Rodriguez E, Dorshkind K. Effects of aging on the common lymphoid progenitor to pro-B cell transition. J Immunol. 2006;176:1007-12.
    • (2006) J Immunol. , vol.176 , pp. 1007-1012
    • Min, H.1    Montecino-Rodriguez, E.2    Dorshkind, K.3
  • 93
    • 77449145533 scopus 로고    scopus 로고
    • Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-β1
    • Challen GA, Boles NC, Chambers SM, Goodell MA. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-β1. Cell Stem Cell. 2010;6:265-78.
    • (2010) Cell Stem Cell. , vol.6 , pp. 265-278
    • Challen, G.A.1    Boles, N.C.2    Chambers, S.M.3    Goodell, M.A.4
  • 94
    • 2942590824 scopus 로고    scopus 로고
    • Senescent B lymphopoiesis is balanced in suppressive homeostasis: Decrease in interleukin-7 and transforming growth factor-beta levels in stromal cells of senescence-accelerated mice
    • Tsuboi I, Morimoto K, Hirabayashi Y, Li GX, Aizawa S, Mori KJ, Kanno J, Inoue T. Senescent B lymphopoiesis is balanced in suppressive homeostasis: decrease in interleukin-7 and transforming growth factor-beta levels in stromal cells of senescence-accelerated mice. Exp Biol Med (Maywood). 2004;229:494-502.
    • (2004) Exp Biol Med (Maywood). , vol.229 , pp. 494-502
    • Tsuboi, I.1    Morimoto, K.2    Hirabayashi, Y.3    Li, G.X.4    Aizawa, S.5    Mori, K.J.6    Kanno, J.7    Inoue, T.8
  • 95
    • 0037438596 scopus 로고    scopus 로고
    • Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice
    • Frasca D, Nguyen D, Riley RL, Blomberg BB. Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice. J Immunol. 2003;170:719-26.
    • (2003) J Immunol. , vol.170 , pp. 719-726
    • Frasca, D.1    Nguyen, D.2    Riley, R.L.3    Blomberg, B.B.4
  • 96
    • 0031035896 scopus 로고    scopus 로고
    • Phenotype of lymphocyte subsets after autologous peripheral blood stem cell transplantation
    • Koehne G, Zeller W, Stockschlaeder M, Zander AR. Phenotype of lymphocyte subsets after autologous peripheral blood stem cell transplantation. Bone Marrow Transplant. 1997;19:149-56.
    • (1997) Bone Marrow Transplant. , vol.19 , pp. 149-156
    • Koehne, G.1    Zeller, W.2    Stockschlaeder, M.3    Zander, A.R.4
  • 98
    • 0035104210 scopus 로고    scopus 로고
    • Impaired regeneration of the peripheral B cell repertoire from bone marrow following lymphopenia in old mice
    • Li F, Jin F, Freitas A, Szabo P, Weksler ME. Impaired regeneration of the peripheral B cell repertoire from bone marrow following lymphopenia in old mice. Eur J Immunol. 2001;31:500-5.
    • (2001) Eur J Immunol. , vol.31 , pp. 500-505
    • Li, F.1    Jin, F.2    Freitas, A.3    Szabo, P.4    Weksler, M.E.5
  • 99
    • 65349134226 scopus 로고    scopus 로고
    • Dendritic cell homeostasis
    • Merad M, Manz MG. Dendritic cell homeostasis. Blood. 2009;113:3418-27.
    • (2009) Blood. , vol.113 , pp. 3418-3427
    • Merad, M.1    Manz, M.G.2
  • 103
    • 79956365255 scopus 로고    scopus 로고
    • Morphological changes in nerve cells during normal aging
    • Pannese E. Morphological changes in nerve cells during normal aging. Brain Struct Funct. 2011;216:85-9.
    • (2011) Brain Struct Funct. , vol.216 , pp. 85-89
    • Pannese, E.1
  • 105
    • 0032526476 scopus 로고    scopus 로고
    • Age changes in stem cells of murine small intestinal crypts
    • Martin K, Kirkwood TBL, Potten CS. Age changes in stem cells of murine small intestinal crypts. Exp Cell Res. 1998;241:316-23.
    • (1998) Exp Cell Res. , vol.241 , pp. 316-323
    • Martin, K.1    Kirkwood, T.B.L.2    Potten, C.S.3
  • 106
    • 81555221816 scopus 로고    scopus 로고
    • Liver regeneration and aging: A current perspective
    • Schmucker DL, Sanchez H. Liver regeneration and aging: a current perspective. Curr Gerontol Geriatr Res. 2011;2011:526379.
    • (2011) Curr Gerontol Geriatr Res. , vol.2011 , pp. 526379
    • Schmucker, D.L.1    Sanchez, H.2
  • 108
    • 17044372889 scopus 로고    scopus 로고
    • CD19 regulates positive selection and maturation in B lymphopoiesis: Lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing
    • Diamant E, Keren Z, Melamed D. CD19 regulates positive selection and maturation in B lymphopoiesis: lack of CD19 imposes developmental arrest of immature B cells and consequential stimulation of receptor editing. Blood. 2005;105:3247-54.
    • (2005) Blood. , vol.105 , pp. 3247-3254
    • Diamant, E.1    Keren, Z.2    Melamed, D.3
  • 109
    • 0029742201 scopus 로고    scopus 로고
    • Requirement for invariant chain in B cell maturation and function
    • Shachar I, Flavell RA. Requirement for invariant chain in B cell maturation and function. Science. 1996;274:106-8.
    • (1996) Science. , vol.274 , pp. 106-108
    • Shachar, I.1    Flavell, R.A.2
  • 110
    • 0036604452 scopus 로고    scopus 로고
    • Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19
    • Shivtiel S, Leider N, Sadeh O, Kraiem Z, Melamed D. Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19. J Immunol. 2002;168:5596-604.
    • (2002) J Immunol. , vol.168 , pp. 5596-5604
    • Shivtiel, S.1    Leider, N.2    Sadeh, O.3    Kraiem, Z.4    Melamed, D.5
  • 111
    • 33646362290 scopus 로고    scopus 로고
    • B-cell targeting in rheumatoid arthritis and other autoimmune diseases
    • Edwards JC, Cambridge G. B-cell targeting in rheumatoid arthritis and other autoimmune diseases. Nat Rev Immunol. 2006;6:394-403.
    • (2006) Nat Rev Immunol. , vol.6 , pp. 394-403
    • Edwards, J.C.1    Cambridge, G.2
  • 112
    • 25144477335 scopus 로고    scopus 로고
    • Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody
    • Rouziere AS, Kneitz C, Palanichamy A, Dorner T, Tony HP. Regeneration of the immunoglobulin heavy-chain repertoire after transient B-cell depletion with an anti-CD20 antibody. Arthritis Res Ther. 2005;7:R714-24.
    • (2005) Arthritis Res Ther. , vol.7
    • Rouziere, A.S.1    Kneitz, C.2    Palanichamy, A.3    Dorner, T.4    Tony, H.P.5
  • 113
    • 2942523585 scopus 로고    scopus 로고
    • Cellular niches controlling B lymphocyte behavior within bone marrow during development
    • Tokoyoda K, Egawa T, Sugiyama T, Choi BI, Nagasawa T. Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity. 2004;20:707-18.
    • (2004) Immunity. , vol.20 , pp. 707-718
    • Tokoyoda, K.1    Egawa, T.2    Sugiyama, T.3    Choi, B.I.4    Nagasawa, T.5
  • 114
    • 54949103952 scopus 로고    scopus 로고
    • Aging of hematopoietic stem cells is regulated by the stem cell niche
    • Wagner W, Horn P, Bork S, Ho AD. Aging of hematopoietic stem cells is regulated by the stem cell niche. Exp Gerontol. 2008;43:974-80.
    • (2008) Exp Gerontol. , vol.43 , pp. 974-980
    • Wagner, W.1    Horn, P.2    Bork, S.3    Ho, A.D.4
  • 118
    • 84862971128 scopus 로고    scopus 로고
    • Aging and impaired immunity to influenza viruses: Implications for vaccine development
    • Liu WM, van der Zeijst BA, Boog CJ, Soethout EC. Aging and impaired immunity to influenza viruses: implications for vaccine development. Hum Vaccin. 2011;7 Suppl:94-8.
    • (2011) Hum Vaccin , vol.7 , Issue.SUPPL. , pp. 94-98
    • Liu, W.M.1    van der Zeijst, B.A.2    Boog, C.J.3    Soethout, E.C.4


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