Reduced EBF expression underlies loss of B-cell potential of hematopoietic progenitors with age

Aging Cell

Volumn 9, Issue 3, 2010, Pages 410-419

  Lescale, Chloé ^a,b   Dias, Sheila ^c,d,g   Maës, Jérôme ^a,b   Cumano, Ana ^c,d   Szabo, Paul ^e   Charron, Dominique ^a,b   Weksler, Marc E ^e   Dosquet, Christine ^a,b,f   Vieira, Paulo ^c,d   Goodhardt, Michele ^a,b  

^a UNIVERSITÉ PARIS DIDEROT   (France)

^b INSERM   (France)

^c INSTITUT PASTEUR   (France)

^d INSTITUT PASTEUR   (France)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

^f SAINT LOUIS HOSPITAL   (France)

^g UNIVERSITY OF CHICAGO   (United States)

Author keywords

Aging; B cells; EBF; Hematopoietic progenitors; STAT5

Indexed keywords

EARLY B CELL FACTOR; STAT5 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PAX5; UNCLASSIFIED DRUG; EBF1 PROTEIN, MOUSE; PAX5 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

AGED; AGING; ARTICLE; B LYMPHOCYTE; CELL FATE; CELL LINEAGE; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; LYMPHOID PROGENITOR CELL; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CYTOLOGY; DOWN REGULATION; GENETICS; METABOLISM;

MUS;

AGING; ANIMALS; B-CELL-SPECIFIC ACTIVATOR PROTEIN; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; DOWN-REGULATION; HEMATOPOIETIC STEM CELLS; MICE; MICE, INBRED C57BL; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS;

EID: 77956685007     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2010.00566.x     Document Type: Article

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