Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans

Seminars in Immunology

Volumn 17, Issue 5, 2005, Pages 378-384

  Frasca, Daniela ^a   Riley, Richard L ^a   Blomberg, Bonnie B ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; B cells; Isotype switch; Transcription factors

Indexed keywords

AGING; ANTIBODY PRODUCTION; B LYMPHOCYTE; CELL FUNCTION; DOWN REGULATION; GENE EXPRESSION; GENE REARRANGEMENT; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; INNATE IMMUNITY; NONHUMAN; REVIEW; SOMATIC HYPERMUTATION;

EID: 23044456776     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.smim.2005.05.005     Document Type: Article

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