Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 12, 2010, Pages 5465-5470

  Beerman, Isabel ^a   Bhattacharya, Deepta ^b   Zandi, Sasan ^c   Sigvardsson, Mikael ^c   Weissman, Irving L ^d   Brydere, David ^e   Rossia, Derrick J ^a  

^a HARVARD STEM CELL INSTITUTE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LINKÖPING UNIVERSITY   (Sweden)

^d STANFORD CANCER INSTITUTE   (United States)

^e LUND UNIVERSITY   (Sweden)

Author keywords

HSCs; Leukemia; Lineage specification

Indexed keywords

ARTICLE; BONE MARROW CELL; CELL AGING; CELL FUNCTION; CELL ISOLATION; CELL LINEAGE; CELL REGENERATION; CELL RENEWAL; CELL SURFACE; EFFECTOR CELL; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; LYMPHOID CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEM CELL EXPANSION;

AGING; ANIMALS; ANTIGENS, CD; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MYELOPOIESIS; RECEPTORS, CELL SURFACE;

EID: 77950418688     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1000834107     Document Type: Article

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