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Volumn 24, Issue 5, 2012, Pages 342-349

B cell maintenance and function in aging

Author keywords

Age; Aging; B cell; B lymphocyte; Humoral immunity

Indexed keywords

B LYMPHOCYTE RECEPTOR; CYCLIN DEPENDENT KINASE INHIBITOR 2A; INFLUENZA VACCINE; NEUTRALIZING ANTIBODY; PNEUMOCOCCUS VACCINE; TELOMERASE REVERSE TRANSCRIPTASE; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; YELLOW FEVER VACCINE; YF 17D;

EID: 84868214102     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2012.04.004     Document Type: Review
Times cited : (132)

References (117)
  • 2
    • 0033559509 scopus 로고    scopus 로고
    • B cell maintenance in aged mice reflects both increased B cell longevity and decreased B cell generation
    • Kline G.H., Hayden T.A., Klinman N.R. B cell maintenance in aged mice reflects both increased B cell longevity and decreased B cell generation. Journal of Immunology 1999, 3342-3349.
    • (1999) Journal of Immunology , pp. 3342-3349
    • Kline, G.H.1    Hayden, T.A.2    Klinman, N.R.3
  • 3
    • 0037094083 scopus 로고    scopus 로고
    • Aging-dependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire
    • Johnson S.A., Rozzo S.J., Cambier J.C. Aging-dependent exclusion of antigen-inexperienced cells from the peripheral B cell repertoire. Journal of Immunology 2002, 168:5014-5023.
    • (2002) Journal of Immunology , vol.168 , pp. 5014-5023
    • Johnson, S.A.1    Rozzo, S.J.2    Cambier, J.C.3
  • 4
    • 67649402297 scopus 로고    scopus 로고
    • Aging in the lympho-hematopoietic stem cell compartment
    • Geiger H., Rudolph K.L. Aging in the lympho-hematopoietic stem cell compartment. Trends in Immunology 2009, 30:360-365.
    • (2009) Trends in Immunology , vol.30 , pp. 360-365
    • Geiger, H.1    Rudolph, K.L.2
  • 5
    • 84855833202 scopus 로고    scopus 로고
    • Aging-associated B7-DC(+) B cells enhance anti-tumor immunity via Th1 and Th17 induction
    • Tomihara K., Shin T., Hurez V.J., Yagita H., Pardoll D.M., Zhang B., et al. Aging-associated B7-DC(+) B cells enhance anti-tumor immunity via Th1 and Th17 induction. Aging Cell 2012, 11:128-138.
    • (2012) Aging Cell , vol.11 , pp. 128-138
    • Tomihara, K.1    Shin, T.2    Hurez, V.J.3    Yagita, H.4    Pardoll, D.M.5    Zhang, B.6
  • 6
    • 0033662327 scopus 로고    scopus 로고
    • The contribution of somatic hypermutation to the diversity of serum immunoglobulin: dramatic increase with age
    • Williams G.T., Jolly C.J., Kohler J., Neuberger M.S. The contribution of somatic hypermutation to the diversity of serum immunoglobulin: dramatic increase with age. Immunity 2000, 13:409-417.
    • (2000) Immunity , vol.13 , pp. 409-417
    • Williams, G.T.1    Jolly, C.J.2    Kohler, J.3    Neuberger, M.S.4
  • 8
    • 59049088629 scopus 로고    scopus 로고
    • B-cell diversity decreases in old age and is correlated with poor health status
    • Gibson K.L., Wu Y.C., Barnett Y., Duggan O., Vaughan R., Kondeatis E., et al. B-cell diversity decreases in old age and is correlated with poor health status. Aging Cell 2009, 8:18-25.
    • (2009) Aging Cell , vol.8 , pp. 18-25
    • Gibson, K.L.1    Wu, Y.C.2    Barnett, Y.3    Duggan, O.4    Vaughan, R.5    Kondeatis, E.6
  • 9
    • 0027252520 scopus 로고
    • Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae
    • Nicoletti C., Yang X., Cerny J. Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae. Journal of Immunology 1993, 150:543-549.
    • (1993) Journal of Immunology , vol.150 , pp. 543-549
    • Nicoletti, C.1    Yang, X.2    Cerny, J.3
  • 10
    • 79960997012 scopus 로고    scopus 로고
    • Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies
    • Sasaki S., Sullivan M., Narvaez C.F., Holmes T.H., Furman D., Zheng N.Y., et al. Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies. Journal of Clinical Investigation 2011, 121:3109-3119.
    • (2011) Journal of Clinical Investigation , vol.121 , pp. 3109-3119
    • Sasaki, S.1    Sullivan, M.2    Narvaez, C.F.3    Holmes, T.H.4    Furman, D.5    Zheng, N.Y.6
  • 11
    • 0031859903 scopus 로고    scopus 로고
    • Altered antibody response to influenza H1N1 vaccine in healthy elderly people as determined by HI, ELISA, and neutralization assay
    • Remarque E.J., de Bruijn I.A., Boersma W.J., Masurel N., Ligthart G.J. Altered antibody response to influenza H1N1 vaccine in healthy elderly people as determined by HI, ELISA, and neutralization assay. Journal of Medical Virology 1998, 55:82-87.
    • (1998) Journal of Medical Virology , vol.55 , pp. 82-87
    • Remarque, E.J.1    de Bruijn, I.A.2    Boersma, W.J.3    Masurel, N.4    Ligthart, G.J.5
  • 12
    • 45949103917 scopus 로고    scopus 로고
    • Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells
    • Frasca D., Landin A.M., Lechner S.C., Ryan J.G., Schwartz R., Riley R.L., et al. Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells. Journal of Immunology 2008, 180:5283-5290.
    • (2008) Journal of Immunology , vol.180 , pp. 5283-5290
    • Frasca, D.1    Landin, A.M.2    Lechner, S.C.3    Ryan, J.G.4    Schwartz, R.5    Riley, R.L.6
  • 14
    • 82855177831 scopus 로고    scopus 로고
    • Elderly subjects have a delayed antibody response and prolonged viraemia following yellow fever vaccination: a prospective controlled cohort study
    • Roukens A.H., Soonawala D., Joosten S.A., de Visser A.W., Jiang X., Dirksen K., et al. Elderly subjects have a delayed antibody response and prolonged viraemia following yellow fever vaccination: a prospective controlled cohort study. PLoS One 2011, 6:e27753.
    • (2011) PLoS One , vol.6
    • Roukens, A.H.1    Soonawala, D.2    Joosten, S.A.3    de Visser, A.W.4    Jiang, X.5    Dirksen, K.6
  • 15
    • 78650518763 scopus 로고    scopus 로고
    • Characterization of main cytokine sources from the innate and adaptive immune responses following primary 17DD yellow fever vaccination in adults
    • Silva M.L., Martins M.A., Espirito-Santo L.R., Campi-Azevedo A.C., Silveira-Lemos D., Ribeiro J.G., et al. Characterization of main cytokine sources from the innate and adaptive immune responses following primary 17DD yellow fever vaccination in adults. Vaccine 2011, 29:583-592.
    • (2011) Vaccine , vol.29 , pp. 583-592
    • Silva, M.L.1    Martins, M.A.2    Espirito-Santo, L.R.3    Campi-Azevedo, A.C.4    Silveira-Lemos, D.5    Ribeiro, J.G.6
  • 16
    • 77958031488 scopus 로고    scopus 로고
    • Thrombin-antithrombin III complex, proinflammatory cytokines, and fibrinolytic indices for assessing the severity of inflammation in pleural effusions
    • Lee M.H., Nahm C.H., Choi J.W. Thrombin-antithrombin III complex, proinflammatory cytokines, and fibrinolytic indices for assessing the severity of inflammation in pleural effusions. Annals of Clinical and Laboratory Science 2010, 40:342-347.
    • (2010) Annals of Clinical and Laboratory Science , vol.40 , pp. 342-347
    • Lee, M.H.1    Nahm, C.H.2    Choi, J.W.3
  • 17
    • 52149084988 scopus 로고    scopus 로고
    • Pneumococcal vaccination in older adults induces antibodies with low opsonic capacity and reduced antibody potency
    • Schenkein J.G., Park S., Nahm M.H. Pneumococcal vaccination in older adults induces antibodies with low opsonic capacity and reduced antibody potency. Vaccine 2008, 26:5521-5526.
    • (2008) Vaccine , vol.26 , pp. 5521-5526
    • Schenkein, J.G.1    Park, S.2    Nahm, M.H.3
  • 18
    • 78650912405 scopus 로고    scopus 로고
    • Older adults have a low capacity to opsonize pneumococci due to low IgM antibody response to pneumococcal vaccinations
    • Park S., Nahm M.H. Older adults have a low capacity to opsonize pneumococci due to low IgM antibody response to pneumococcal vaccinations. Infection and Immunity 2011, 79:314-320.
    • (2011) Infection and Immunity , vol.79 , pp. 314-320
    • Park, S.1    Nahm, M.H.2
  • 19
    • 81155152466 scopus 로고    scopus 로고
    • Vaccination-induced changes in human B-cell repertoire and pneumococcal IgM and IgA antibody at different ages
    • Ademokun A., Wu Y.C., Martin V., Mitra R., Sack U., Baxendale H., et al. Vaccination-induced changes in human B-cell repertoire and pneumococcal IgM and IgA antibody at different ages. Aging Cell 2011, 10:922-930.
    • (2011) Aging Cell , vol.10 , pp. 922-930
    • Ademokun, A.1    Wu, Y.C.2    Martin, V.3    Mitra, R.4    Sack, U.5    Baxendale, H.6
  • 21
    • 78649960164 scopus 로고    scopus 로고
    • Potentiation of Th17 cytokines in aging process contributes to the development of colitis
    • Ouyang X., Yang Z., Zhang R., Arnaboldi P., Lu G., Li Q., et al. Potentiation of Th17 cytokines in aging process contributes to the development of colitis. Cellular Immunology 2011, 266:208-217.
    • (2011) Cellular Immunology , vol.266 , pp. 208-217
    • Ouyang, X.1    Yang, Z.2    Zhang, R.3    Arnaboldi, P.4    Lu, G.5    Li, Q.6
  • 22
    • 3342995295 scopus 로고    scopus 로고
    • Inflamm-aging: autoimmunity, and the immune-risk phenotype
    • Boren E., Gershwin M.E. Inflamm-aging: autoimmunity, and the immune-risk phenotype. Autoimmunity Reviews 2004, 3:401-406.
    • (2004) Autoimmunity Reviews , vol.3 , pp. 401-406
    • Boren, E.1    Gershwin, M.E.2
  • 24
    • 80051568169 scopus 로고    scopus 로고
    • TLR7-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity
    • Rubtsov A.V., Rubtsova K., Fischer A., Meehan R.T., Gillis J.Z., Kappler J.W., et al. TLR7-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity. Blood 2011, 1305-1315.
    • (2011) Blood , pp. 1305-1315
    • Rubtsov, A.V.1    Rubtsova, K.2    Fischer, A.3    Meehan, R.T.4    Gillis, J.Z.5    Kappler, J.W.6
  • 26
    • 84855410220 scopus 로고    scopus 로고
    • Concise review: multidimensional regulation of the hematopoietic stem cell state
    • Oh I.H., Humphries R.K. Concise review: multidimensional regulation of the hematopoietic stem cell state. Stem Cells 2012, 30:82-88.
    • (2012) Stem Cells , vol.30 , pp. 82-88
    • Oh, I.H.1    Humphries, R.K.2
  • 27
    • 77449093887 scopus 로고    scopus 로고
    • Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior
    • Schroeder T. Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior. Cell Stem Cell 2010, 6:203-207.
    • (2010) Cell Stem Cell , vol.6 , pp. 203-207
    • Schroeder, T.1
  • 29
    • 34548489639 scopus 로고    scopus 로고
    • Fate decisions regulating bone marrow and peripheral B lymphocyte development
    • Monroe J.G., Dorshkind K. Fate decisions regulating bone marrow and peripheral B lymphocyte development. Advances in Immunology 2007, 95:1-50.
    • (2007) Advances in Immunology , vol.95 , pp. 1-50
    • Monroe, J.G.1    Dorshkind, K.2
  • 31
    • 67649410701 scopus 로고    scopus 로고
    • An evolutionary perspective on the mechanisms of immunosenescence
    • Shanley D.P., Aw D., Manley N.R., Palmer D.B. An evolutionary perspective on the mechanisms of immunosenescence. Trends in Immunology 2009, 30:374-381.
    • (2009) Trends in Immunology , vol.30 , pp. 374-381
    • Shanley, D.P.1    Aw, D.2    Manley, N.R.3    Palmer, D.B.4
  • 32
    • 47049099198 scopus 로고    scopus 로고
    • A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells
    • Cho R.H., Sieburg H.B., Muller-Sieburg C.E. A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells. Blood 2008, 111:5553-5561.
    • (2008) Blood , vol.111 , pp. 5553-5561
    • Cho, R.H.1    Sieburg, H.B.2    Muller-Sieburg, C.E.3
  • 33
    • 37449004696 scopus 로고    scopus 로고
    • Hematopoietic stem cell aging and self-renewal
    • Dykstra B., de Haan G. Hematopoietic stem cell aging and self-renewal. Cell and Tissue Research 2008, 331:91-101.
    • (2008) Cell and Tissue Research , vol.331 , pp. 91-101
    • Dykstra, B.1    de Haan, G.2
  • 34
    • 58149388235 scopus 로고    scopus 로고
    • Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach
    • Roeder I., Horn K., Sieburg H.B., Cho R., Muller-Sieburg C., Loeffler M. Characterization and quantification of clonal heterogeneity among hematopoietic stem cells: a model-based approach. Blood 2008, 112:4874-4883.
    • (2008) Blood , vol.112 , pp. 4874-4883
    • Roeder, I.1    Horn, K.2    Sieburg, H.B.3    Cho, R.4    Muller-Sieburg, C.5    Loeffler, M.6
  • 37
    • 77449145533 scopus 로고    scopus 로고
    • Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1
    • Challen G.A., Boles N.C., Chambers S.M., Goodell M.A. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell 2010, 6:265-278.
    • (2010) Cell Stem Cell , vol.6 , pp. 265-278
    • Challen, G.A.1    Boles, N.C.2    Chambers, S.M.3    Goodell, M.A.4
  • 38
    • 34547692981 scopus 로고    scopus 로고
    • Long-term propagation of distinct hematopoietic differentiation programs in vivo
    • Dykstra B., Kent D., Bowie M., McCaffrey L., Hamilton M., Lyons K., et al. Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell 2007, 1:218-229.
    • (2007) Cell Stem Cell , vol.1 , pp. 218-229
    • Dykstra, B.1    Kent, D.2    Bowie, M.3    McCaffrey, L.4    Hamilton, M.5    Lyons, K.6
  • 39
    • 33644781621 scopus 로고    scopus 로고
    • The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets
    • Sieburg H.B., Cho R.H., Dykstra B., Uchida N., Eaves C.J., Muller-Sieburg C.E. The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets. Blood 2006, 107:2311-2316.
    • (2006) Blood , vol.107 , pp. 2311-2316
    • Sieburg, H.B.1    Cho, R.H.2    Dykstra, B.3    Uchida, N.4    Eaves, C.J.5    Muller-Sieburg, C.E.6
  • 44
    • 0035496909 scopus 로고    scopus 로고
    • Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age
    • Kollman C., Howe C.W., Anasetti C., Antin J.H., Davies S.M., Filipovich A.H., et al. Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood 2001, 98:2043-2051.
    • (2001) Blood , vol.98 , pp. 2043-2051
    • Kollman, C.1    Howe, C.W.2    Anasetti, C.3    Antin, J.H.4    Davies, S.M.5    Filipovich, A.H.6
  • 46
    • 84856746717 scopus 로고    scopus 로고
    • Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease
    • Herrera-Merchan A., Arranz L., Ligos J.M., de Molina A., Dominguez O., Gonzalez S. Ectopic expression of the histone methyltransferase Ezh2 in haematopoietic stem cells causes myeloproliferative disease. Nature Communications 2012, 3:623.
    • (2012) Nature Communications , vol.3 , pp. 623
    • Herrera-Merchan, A.1    Arranz, L.2    Ligos, J.M.3    de Molina, A.4    Dominguez, O.5    Gonzalez, S.6
  • 47
    • 77956902023 scopus 로고    scopus 로고
    • Comprehensive methylome map of lineage commitment from haematopoietic progenitors
    • Ji H., Ehrlich L.I., Seita J., Murakami P., Doi A., Lindau P., et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 2010, 467:338-342.
    • (2010) Nature , vol.467 , pp. 338-342
    • Ji, H.1    Ehrlich, L.I.2    Seita, J.3    Murakami, P.4    Doi, A.5    Lindau, P.6
  • 48
    • 79955970344 scopus 로고    scopus 로고
    • Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging
    • Bocker M.T., Hellwig I., Breiling A., Eckstein V., Ho A.D., Lyko F. Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging. Blood 2011, 117:e182-e189.
    • (2011) Blood , vol.117
    • Bocker, M.T.1    Hellwig, I.2    Breiling, A.3    Eckstein, V.4    Ho, A.D.5    Lyko, F.6
  • 49
    • 77949518018 scopus 로고    scopus 로고
    • MicroRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
    • Han Y.C., Park C.Y., Bhagat G., Zhang J., Wang Y., Fan J.B., et al. microRNA-29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. Journal of Experimental Medicine 2010, 207:475-489.
    • (2010) Journal of Experimental Medicine , vol.207 , pp. 475-489
    • Han, Y.C.1    Park, C.Y.2    Bhagat, G.3    Zhang, J.4    Wang, Y.5    Fan, J.B.6
  • 52
    • 80052930073 scopus 로고    scopus 로고
    • Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells
    • Yahata T., Takanashi T., Muguruma Y., Ibrahim A.A., Matsuzawa H., Uno T., et al. Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells. Blood 2011, 118:2941-2950.
    • (2011) Blood , vol.118 , pp. 2941-2950
    • Yahata, T.1    Takanashi, T.2    Muguruma, Y.3    Ibrahim, A.A.4    Matsuzawa, H.5    Uno, T.6
  • 54
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
    • Rossi D.J., Bryder D., Seita J., Nussenzweig A., Hoeijmakers J., Weissman I.L. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature 2007, 447:725-729.
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1    Bryder, D.2    Seita, J.3    Nussenzweig, A.4    Hoeijmakers, J.5    Weissman, I.L.6
  • 55
    • 0033525558 scopus 로고    scopus 로고
    • Longevity, stress response, and cancer in aging telomerase-deficient mice
    • Rudolph K.L., Chang S., Lee H.W., Blasco M., Gottlieb G.J., Greider C., et al. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell 1999, 96:701-712.
    • (1999) Cell , vol.96 , pp. 701-712
    • Rudolph, K.L.1    Chang, S.2    Lee, H.W.3    Blasco, M.4    Gottlieb, G.J.5    Greider, C.6
  • 57
    • 79952338609 scopus 로고    scopus 로고
    • Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging
    • Rube C.E., Fricke A., Widmann T.A., Furst T., Madry H., Pfreundschuh M., et al. Accumulation of DNA damage in hematopoietic stem and progenitor cells during human aging. PLoS One 2011, 6:e17487.
    • (2011) PLoS One , vol.6
    • Rube, C.E.1    Fricke, A.2    Widmann, T.A.3    Furst, T.4    Madry, H.5    Pfreundschuh, M.6
  • 59
    • 79953735503 scopus 로고    scopus 로고
    • Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins
    • Ameur A., Stewart J.B., Freyer C., Hagstrom E., Ingman M., Larsson N.G., et al. Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins. PLoS Genetics 2011, 7:e1002028.
    • (2011) PLoS Genetics , vol.7
    • Ameur, A.1    Stewart, J.B.2    Freyer, C.3    Hagstrom, E.4    Ingman, M.5    Larsson, N.G.6
  • 60
    • 77950265945 scopus 로고    scopus 로고
    • Linking functional decline of telomeres, mitochondria and stem cells during ageing
    • Sahin E., Depinho R.A. Linking functional decline of telomeres, mitochondria and stem cells during ageing. Nature 2010, 464:520-528.
    • (2010) Nature , vol.464 , pp. 520-528
    • Sahin, E.1    Depinho, R.A.2
  • 61
    • 33749172559 scopus 로고    scopus 로고
    • Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
    • Janzen V., Forkert R., Fleming H.E., Saito Y., Waring M.T., Dombkowski D.M., et al. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature 2006, 443:421-426.
    • (2006) Nature , vol.443 , pp. 421-426
    • Janzen, V.1    Forkert, R.2    Fleming, H.E.3    Saito, Y.4    Waring, M.T.5    Dombkowski, D.M.6
  • 64
    • 79953086335 scopus 로고    scopus 로고
    • Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes
    • Liu Y., Johnson S.M., Fedoriw Y., Rogers A.B., Yuan H., Krishnamurthy J., et al. Expression of p16(INK4a) prevents cancer and promotes aging in lymphocytes. Blood 2011, 117:3257-3267.
    • (2011) Blood , vol.117 , pp. 3257-3267
    • Liu, Y.1    Johnson, S.M.2    Fedoriw, Y.3    Rogers, A.B.4    Yuan, H.5    Krishnamurthy, J.6
  • 65
    • 79951812916 scopus 로고    scopus 로고
    • Telomere dysfunction induces metabolic and mitochondrial compromise
    • Sahin E., Colla S., Liesa M., Moslehi J., Muller F.L., Guo M., et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 2011, 470:359-365.
    • (2011) Nature , vol.470 , pp. 359-365
    • Sahin, E.1    Colla, S.2    Liesa, M.3    Moslehi, J.4    Muller, F.L.5    Guo, M.6
  • 66
    • 78650990326 scopus 로고    scopus 로고
    • Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
    • Jaskelioff M., Muller F.L., Paik J.H., Thomas E., Jiang S., Adams A.C., et al. Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature 2011, 469:102-106.
    • (2011) Nature , vol.469 , pp. 102-106
    • Jaskelioff, M.1    Muller, F.L.2    Paik, J.H.3    Thomas, E.4    Jiang, S.5    Adams, A.C.6
  • 67
    • 79955778862 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism
    • Nitta E., Yamashita M., Hosokawa K., Xian M., Takubo K., Arai F., et al. Telomerase reverse transcriptase protects ATM-deficient hematopoietic stem cells from ROS-induced apoptosis through a telomere-independent mechanism. Blood 2011, 117:4169-4180.
    • (2011) Blood , vol.117 , pp. 4169-4180
    • Nitta, E.1    Yamashita, M.2    Hosokawa, K.3    Xian, M.4    Takubo, K.5    Arai, F.6
  • 68
    • 84856147560 scopus 로고    scopus 로고
    • Endothelial and perivascular cells maintain haematopoietic stem cells
    • Ding L., Saunders T.L., Enikolopov G., Morrison S.J. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature 2012, 481:457-462.
    • (2012) Nature , vol.481 , pp. 457-462
    • Ding, L.1    Saunders, T.L.2    Enikolopov, G.3    Morrison, S.J.4
  • 70
    • 79953097625 scopus 로고    scopus 로고
    • B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging
    • Keren Z., Naor S., Nussbaum S., Golan K., Itkin T., Sasaki Y., et al. B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging. Blood 2011, 117:3104-3112.
    • (2011) Blood , vol.117 , pp. 3104-3112
    • Keren, Z.1    Naor, S.2    Nussbaum, S.3    Golan, K.4    Itkin, T.5    Sasaki, Y.6
  • 71
    • 80052687220 scopus 로고    scopus 로고
    • Chronic B cell deficiency from birth prevents age-related alterations in the B lineage
    • Keren Z., Averbuch D., Shahaf G., Zisman-Rozen S., Golan K., Itkin T., et al. Chronic B cell deficiency from birth prevents age-related alterations in the B lineage. Journal of Immunology 2011, 187:2140-2147.
    • (2011) Journal of Immunology , vol.187 , pp. 2140-2147
    • Keren, Z.1    Averbuch, D.2    Shahaf, G.3    Zisman-Rozen, S.4    Golan, K.5    Itkin, T.6
  • 73
    • 32544437957 scopus 로고    scopus 로고
    • Initiation of pre-B cell receptor signaling: common and distinctive features in human and mouse
    • Espeli M., Rossi B., Mancini S.J., Roche P., Gauthier L., Schiff C. Initiation of pre-B cell receptor signaling: common and distinctive features in human and mouse. Seminars in Immunology 2006, 18:56-66.
    • (2006) Seminars in Immunology , vol.18 , pp. 56-66
    • Espeli, M.1    Rossi, B.2    Mancini, S.J.3    Roche, P.4    Gauthier, L.5    Schiff, C.6
  • 74
    • 27144538299 scopus 로고    scopus 로고
    • Gene expression patterns in human and mouse B cell development
    • Hoffmann R. Gene expression patterns in human and mouse B cell development. Current Topics in Microbiology and Immunology 2005, 294:19-29.
    • (2005) Current Topics in Microbiology and Immunology , vol.294 , pp. 19-29
    • Hoffmann, R.1
  • 75
    • 33846104336 scopus 로고    scopus 로고
    • B cell reconstitution after rituximab treatment of lymphoma recapitulates B cell ontogeny
    • Anolik J.H., Friedberg J.W., Zheng B., Barnard J., Owen T., Cushing E., et al. B cell reconstitution after rituximab treatment of lymphoma recapitulates B cell ontogeny. Clinical Immunology 2007, 122:139-145.
    • (2007) Clinical Immunology , vol.122 , pp. 139-145
    • Anolik, J.H.1    Friedberg, J.W.2    Zheng, B.3    Barnard, J.4    Owen, T.5    Cushing, E.6
  • 76
    • 72449140060 scopus 로고    scopus 로고
    • Novel human transitional B cell populations revealed by B cell depletion therapy
    • Palanichamy A., Barnard J., Zheng B., Owen T., Quach T., Wei C., et al. Novel human transitional B cell populations revealed by B cell depletion therapy. Journal of Immunology 2009, 182:5982-5993.
    • (2009) Journal of Immunology , vol.182 , pp. 5982-5993
    • Palanichamy, A.1    Barnard, J.2    Zheng, B.3    Owen, T.4    Quach, T.5    Wei, C.6
  • 77
    • 77449159423 scopus 로고    scopus 로고
    • Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells
    • Suryani S., Fulcher D.A., Santner-Nanan B., Nanan R., Wong M., Shaw P.J., et al. Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells. Blood 2010, 115:519-529.
    • (2010) Blood , vol.115 , pp. 519-529
    • Suryani, S.1    Fulcher, D.A.2    Santner-Nanan, B.3    Nanan, R.4    Wong, M.5    Shaw, P.J.6
  • 78
    • 9644266695 scopus 로고    scopus 로고
    • The BLyS family of ligands and receptors: an archetype for niche-specific homeostatic regulation
    • Cancro M.P. The BLyS family of ligands and receptors: an archetype for niche-specific homeostatic regulation. Immunological Reviews 2004, 202:237-249.
    • (2004) Immunological Reviews , vol.202 , pp. 237-249
    • Cancro, M.P.1
  • 80
    • 70349336151 scopus 로고    scopus 로고
    • B cell receptor and BAFF receptor signaling regulation of B cell homeostasis
    • Khan W.N. B cell receptor and BAFF receptor signaling regulation of B cell homeostasis. Journal of Immunology 2009, 183:3561-3567.
    • (2009) Journal of Immunology , vol.183 , pp. 3561-3567
    • Khan, W.N.1
  • 82
    • 0028151819 scopus 로고
    • Negative selection of lymphocytes
    • Nossal G.J. Negative selection of lymphocytes. Cell 1994, 76:229-239.
    • (1994) Cell , vol.76 , pp. 229-239
    • Nossal, G.J.1
  • 85
    • 19344376101 scopus 로고    scopus 로고
    • Identification and characterization of circulating human transitional B cells
    • Sims G.P., Ettinger R., Shirota Y., Yarboro C.H., Illei G.G., Lipsky P.E. Identification and characterization of circulating human transitional B cells. Blood 2005, 105:4390-4398.
    • (2005) Blood , vol.105 , pp. 4390-4398
    • Sims, G.P.1    Ettinger, R.2    Shirota, Y.3    Yarboro, C.H.4    Illei, G.G.5    Lipsky, P.E.6
  • 88
    • 79960918034 scopus 로고    scopus 로고
    • BAFF and selection of autoreactive B cells
    • Liu Z., Davidson A. BAFF and selection of autoreactive B cells. Trends in Immunology 2011, 32:388-394.
    • (2011) Trends in Immunology , vol.32 , pp. 388-394
    • Liu, Z.1    Davidson, A.2
  • 90
    • 0042931219 scopus 로고    scopus 로고
    • The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors
    • Miller J.P., Allman D. The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors. Journal of Immunology 2003, 171:2326-2330.
    • (2003) Journal of Immunology , vol.171 , pp. 2326-2330
    • Miller, J.P.1    Allman, D.2
  • 91
    • 1642503856 scopus 로고    scopus 로고
    • Age-related differences in the E2A-encoded transcription factor E47 in bone marrow-derived B cell precursors and in splenic B cells
    • Frasca D., Van Der Put E., Riley R.L., Blomberg B.B. Age-related differences in the E2A-encoded transcription factor E47 in bone marrow-derived B cell precursors and in splenic B cells. Experimental Gerontology 2004, 39:481-489.
    • (2004) Experimental Gerontology , vol.39 , pp. 481-489
    • Frasca, D.1    Van Der Put, E.2    Riley, R.L.3    Blomberg, B.B.4
  • 92
    • 4344599559 scopus 로고    scopus 로고
    • Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice
    • Labrie J.E., Sah A.P., Allman D.M., Cancro M.P., Gerstein R.M. Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice. Journal of Experimental Medicine 2004, 200:411-423.
    • (2004) Journal of Experimental Medicine , vol.200 , pp. 411-423
    • Labrie, J.E.1    Sah, A.P.2    Allman, D.M.3    Cancro, M.P.4    Gerstein, R.M.5
  • 93
    • 59849105341 scopus 로고    scopus 로고
    • Deviation of the B cell pathway in senescent mice is associated with reduced surrogate light chain expression and altered immature B cell generation, phenotype, and light chain expression
    • Alter-Wolf S., Blomberg B.B., Riley R.L. Deviation of the B cell pathway in senescent mice is associated with reduced surrogate light chain expression and altered immature B cell generation, phenotype, and light chain expression. Journal of Immunology 2009, 182:138-147.
    • (2009) Journal of Immunology , vol.182 , pp. 138-147
    • Alter-Wolf, S.1    Blomberg, B.B.2    Riley, R.L.3
  • 94
    • 0031985281 scopus 로고    scopus 로고
    • Impaired ability of bone marrow stromal cells to support B-lymphopoiesis with age
    • Stephan R.P., Reilly C.R., Witte P.L. Impaired ability of bone marrow stromal cells to support B-lymphopoiesis with age. Blood 1998, 91:75-88.
    • (1998) Blood , vol.91 , pp. 75-88
    • Stephan, R.P.1    Reilly, C.R.2    Witte, P.L.3
  • 95
    • 23044433012 scopus 로고    scopus 로고
    • Connecting the dots: revealing the interactions of lymphocyte development and homeostasis in the immunobiology of aging
    • Cancro M.P., Allman D.M. Connecting the dots: revealing the interactions of lymphocyte development and homeostasis in the immunobiology of aging. Seminars in Immunology 2005, 17:319-320.
    • (2005) Seminars in Immunology , vol.17 , pp. 319-320
    • Cancro, M.P.1    Allman, D.M.2
  • 96
    • 34147122646 scopus 로고    scopus 로고
    • B cells and aging: balancing the homeostatic equation
    • Miller J.P., Cancro M.P. B cells and aging: balancing the homeostatic equation. Experimental Gerontology 2007, 42:396-399.
    • (2007) Experimental Gerontology , vol.42 , pp. 396-399
    • Miller, J.P.1    Cancro, M.P.2
  • 97
    • 23044501423 scopus 로고    scopus 로고
    • Dwindling competition with constant demand: can homeostatic adjustments explain age-associated changes in peripheral B cell selection?
    • Quinn W.J., Scholz J.L., Cancro M.P. Dwindling competition with constant demand: can homeostatic adjustments explain age-associated changes in peripheral B cell selection?. Seminars in Immunology 2005, 17:362-369.
    • (2005) Seminars in Immunology , vol.17 , pp. 362-369
    • Quinn, W.J.1    Scholz, J.L.2    Cancro, M.P.3
  • 98
    • 0033962638 scopus 로고    scopus 로고
    • Changes in the B-cell repertoire with age
    • Weksler M.E. Changes in the B-cell repertoire with age. Vaccine 2000, 18:1624-1628.
    • (2000) Vaccine , vol.18 , pp. 1624-1628
    • Weksler, M.E.1
  • 99
    • 33847204581 scopus 로고    scopus 로고
    • Fetal B-cell lymphopoiesis and the emergence of B-1-cell potential
    • Dorshkind K., Montecino-Rodriguez E. Fetal B-cell lymphopoiesis and the emergence of B-1-cell potential. Nature Reviews Immunology 2007, 7:213-219.
    • (2007) Nature Reviews Immunology , vol.7 , pp. 213-219
    • Dorshkind, K.1    Montecino-Rodriguez, E.2
  • 100
    • 77950857568 scopus 로고    scopus 로고
    • The ageing B cell population: composition and function
    • Ademokun A., Wu Y.C., Dunn-Walters D. The ageing B cell population: composition and function. Biogerontology 2010, 11:125-137.
    • (2010) Biogerontology , vol.11 , pp. 125-137
    • Ademokun, A.1    Wu, Y.C.2    Dunn-Walters, D.3
  • 104
    • 80051569441 scopus 로고    scopus 로고
    • A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice
    • Hao Y., O'Neill P.J., Naradikian M.S., Scholz J.L., Cancro M.P. A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. Blood 2011, 12194-12304.
    • (2011) Blood , pp. 12194-12304
    • Hao, Y.1    O'Neill, P.J.2    Naradikian, M.S.3    Scholz, J.L.4    Cancro, M.P.5
  • 105
    • 77955898582 scopus 로고    scopus 로고
    • T cells and follicular dendritic cells in germinal center B-cell formation and selection
    • Vinuesa C.G., Linterman M.A., Goodnow C.C., Randall K.L. T cells and follicular dendritic cells in germinal center B-cell formation and selection. Immunological Reviews 2010, 237:72-89.
    • (2010) Immunological Reviews , vol.237 , pp. 72-89
    • Vinuesa, C.G.1    Linterman, M.A.2    Goodnow, C.C.3    Randall, K.L.4
  • 107
    • 70749100503 scopus 로고    scopus 로고
    • The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints
    • Vuyyuru R., Mohan C., Manser T., Rahman Z.S. The lupus susceptibility locus Sle1 breaches peripheral B cell tolerance at the antibody-forming cell and germinal center checkpoints. Journal of Immunology 2009, 183:5716-5727.
    • (2009) Journal of Immunology , vol.183 , pp. 5716-5727
    • Vuyyuru, R.1    Mohan, C.2    Manser, T.3    Rahman, Z.S.4
  • 108
    • 32044454695 scopus 로고    scopus 로고
    • B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation
    • William J., Euler C., Primarolo N., Shlomchik M.J. B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation. Journal of Immunology 2006, 176:2142-2151.
    • (2006) Journal of Immunology , vol.176 , pp. 2142-2151
    • William, J.1    Euler, C.2    Primarolo, N.3    Shlomchik, M.J.4
  • 109
    • 23044456776 scopus 로고    scopus 로고
    • Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans
    • Frasca D., Riley R.L., Blomberg B.B. Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans. Seminars in Immunology 2005, 17:378-384.
    • (2005) Seminars in Immunology , vol.17 , pp. 378-384
    • Frasca, D.1    Riley, R.L.2    Blomberg, B.B.3
  • 111
    • 44849097480 scopus 로고    scopus 로고
    • Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL
    • Benson M.J., Dillon S.R., Castigli E., Geha R.S., Xu S., Lam K.P., et al. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. Journal of Immunology 2008, 180:3655-3659.
    • (2008) Journal of Immunology , vol.180 , pp. 3655-3659
    • Benson, M.J.1    Dillon, S.R.2    Castigli, E.3    Geha, R.S.4    Xu, S.5    Lam, K.P.6
  • 112
    • 41949138741 scopus 로고    scopus 로고
    • APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells
    • Belnoue E., Pihlgren M., McGaha T.L., Tougne C., Rochat A.F., Bossen C., et al. APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells. Blood 2008, 111:2755-2764.
    • (2008) Blood , vol.111 , pp. 2755-2764
    • Belnoue, E.1    Pihlgren, M.2    McGaha, T.L.3    Tougne, C.4    Rochat, A.F.5    Bossen, C.6
  • 114
    • 20844450563 scopus 로고    scopus 로고
    • Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells
    • Muehlinghaus G., Cigliano L., Huehn S., Peddinghaus A., Leyendeckers H., Hauser A.E., et al. Regulation of CXCR3 and CXCR4 expression during terminal differentiation of memory B cells into plasma cells. Blood 2005, 105:3965-3971.
    • (2005) Blood , vol.105 , pp. 3965-3971
    • Muehlinghaus, G.1    Cigliano, L.2    Huehn, S.3    Peddinghaus, A.4    Leyendeckers, H.5    Hauser, A.E.6
  • 115


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