-
1
-
-
0035898937
-
Immune responses and protection in different strains of aged mice immunized intranasally with an adjuvant-combined influenza vaccine
-
Asanuma H, Hirokawa K, Uchiyama M, Suzuki Y, Aizawa C, Kurata T, Sata T, Tamura S (2001) Immune responses and protection in different strains of aged mice immunized intranasally with an adjuvant-combined influenza vaccine. Vaccine 19, 3981-3989.
-
(2001)
Vaccine
, vol.19
, pp. 3981-3989
-
-
Asanuma, H.1
Hirokawa, K.2
Uchiyama, M.3
Suzuki, Y.4
Aizawa, C.5
Kurata, T.6
Sata, T.7
Tamura, S.8
-
2
-
-
67649397918
-
B cells and aging: molecules and mechanisms
-
Cancro MP, Hao Y, Scholz JL, Riley RL, Frasca D, Dunn-Walters DK, Blomberg BB (2009) B cells and aging: molecules and mechanisms. Trends Immunol. 30, 313-318.
-
(2009)
Trends Immunol.
, vol.30
, pp. 313-318
-
-
Cancro, M.P.1
Hao, Y.2
Scholz, J.L.3
Riley, R.L.4
Frasca, D.5
Dunn-Walters, D.K.6
Blomberg, B.B.7
-
3
-
-
0037435404
-
A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes
-
Diaz M, Storb U (2003) A novel cytidine deaminase AIDs in the delivery of error-prone polymerases to immunoglobulin genes. DNA Repair (Amst) 2, 623-627.
-
(2003)
DNA Repair (Amst)
, vol.2
, pp. 623-627
-
-
Diaz, M.1
Storb, U.2
-
5
-
-
0021928806
-
B lineage - specific interactions of an immunoglobulin enhancer with cellular factors in vivo
-
Ephrussi A, Church GM, Tonegawa S, Gilbert W (1985) B lineage - specific interactions of an immunoglobulin enhancer with cellular factors in vivo. Science 227, 134-140.
-
(1985)
Science
, vol.227
, pp. 134-140
-
-
Ephrussi, A.1
Church, G.M.2
Tonegawa, S.3
Gilbert, W.4
-
7
-
-
0037438596
-
Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice
-
Frasca D, Nguyen D, Riley RL, Blomberg BB (2003) Decreased E12 and/or E47 transcription factor activity in the bone marrow as well as in the spleen of aged mice. J. Immunol. 170, 719-726.
-
(2003)
J. Immunol.
, vol.170
, pp. 719-726
-
-
Frasca, D.1
Nguyen, D.2
Riley, R.L.3
Blomberg, B.B.4
-
8
-
-
0842281257
-
Effects of aging on DNA-binding activity of the E47 transcription factor in splenic B cells
-
Frasca D, Nguyen D, Riley RL, Blomberg BB (2004a) Effects of aging on DNA-binding activity of the E47 transcription factor in splenic B cells. Mech. Ageing Dev. 125, 111-112.
-
(2004)
Mech. Ageing Dev.
, vol.125
, pp. 111-112
-
-
Frasca, D.1
Nguyen, D.2
Riley, R.L.3
Blomberg, B.B.4
-
9
-
-
0842321787
-
Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase
-
Frasca D, Van der Put E, Riley RL, Blomberg BB (2004b) Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase. J. Immunol. 172, 2155-2162.
-
(2004)
J. Immunol.
, vol.172
, pp. 2155-2162
-
-
Frasca, D.1
Van der Put, E.2
Riley, R.L.3
Blomberg, B.B.4
-
10
-
-
27744483838
-
RNA stability of the E2A-encoded transcription factor E47 is lower in splenic activated B cells from aged mice
-
Frasca D, Van der Put E, Landin AM, Gong D, Riley RL, Blomberg BB (2005) RNA stability of the E2A-encoded transcription factor E47 is lower in splenic activated B cells from aged mice. J. Immunol. 175, 6633-6644.
-
(2005)
J. Immunol.
, vol.175
, pp. 6633-6644
-
-
Frasca, D.1
Van der Put, E.2
Landin, A.M.3
Gong, D.4
Riley, R.L.5
Blomberg, B.B.6
-
11
-
-
34548754592
-
Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA
-
Frasca D, Landin AM, Alvarez JP, Blackshear PJ, Riley RL, Blomberg BB (2007) Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA. J. Immunol. 179, 918-927.
-
(2007)
J. Immunol.
, vol.179
, pp. 918-927
-
-
Frasca, D.1
Landin, A.M.2
Alvarez, J.P.3
Blackshear, P.J.4
Riley, R.L.5
Blomberg, B.B.6
-
12
-
-
45949103917
-
Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells
-
Frasca D, Landin AM, Lechner SC, Ryan JG, Schwartz R, Riley RL, Blomberg BB (2008a) Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells. J. Immunol. 180, 5283-5290.
-
(2008)
J. Immunol.
, vol.180
, pp. 5283-5290
-
-
Frasca, D.1
Landin, A.M.2
Lechner, S.C.3
Ryan, J.G.4
Schwartz, R.5
Riley, R.L.6
Blomberg, B.B.7
-
13
-
-
49149127677
-
Mechanisms for decreased function of B cells in aged mice and humans
-
Frasca D, Landin AM, Riley RL, Blomberg BB (2008b) Mechanisms for decreased function of B cells in aged mice and humans. J. Immunol. 180, 2741-2746.
-
(2008)
J. Immunol.
, vol.180
, pp. 2741-2746
-
-
Frasca, D.1
Landin, A.M.2
Riley, R.L.3
Blomberg, B.B.4
-
14
-
-
79952609866
-
Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans
-
Frasca D, Diaz A, Romero M, Landin AM, Phillips M, Lechner SC, Ryan JG, Blomberg BB (2010a) Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans. Vaccine 18, 1591-1595.
-
(2010)
Vaccine
, vol.18
, pp. 1591-1595
-
-
Frasca, D.1
Diaz, A.2
Romero, M.3
Landin, A.M.4
Phillips, M.5
Lechner, S.C.6
Ryan, J.G.7
Blomberg, B.B.8
-
15
-
-
77953050555
-
Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability
-
Frasca D, Romero M, Landin AM, Diaz A, Riley RL, Blomberg BB (2010b) Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability. Mech. Ageing Dev. 131, 306-314.
-
(2010)
Mech. Ageing Dev.
, vol.131
, pp. 306-314
-
-
Frasca, D.1
Romero, M.2
Landin, A.M.3
Diaz, A.4
Riley, R.L.5
Blomberg, B.B.6
-
16
-
-
33845958028
-
Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production
-
Gong D, Malek TR (2007) Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production. J. Immunol. 178, 242-252.
-
(2007)
J. Immunol.
, vol.178
, pp. 242-252
-
-
Gong, D.1
Malek, T.R.2
-
17
-
-
67651151156
-
Immunosenescence and vaccine failure in the elderly
-
Grubeck-Loebenstein B, Della Bella S, Iorio AM, Michel JP, Pawelec G, Solana R (2009) Immunosenescence and vaccine failure in the elderly. Aging Clin Exp Res 21, 201-209.
-
(2009)
Aging Clin Exp Res
, vol.21
, pp. 201-209
-
-
Grubeck-Loebenstein, B.1
Della Bella, S.2
Iorio, A.M.3
Michel, J.P.4
Pawelec, G.5
Solana, R.6
-
18
-
-
0037310619
-
Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice
-
Han S, Yang K, Ozen Z, Peng W, Marinova E, Kelsoe G, Zheng B (2003) Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice. J. Immunol. 170, 1267-1273.
-
(2003)
J. Immunol.
, vol.170
, pp. 1267-1273
-
-
Han, S.1
Yang, K.2
Ozen, Z.3
Peng, W.4
Marinova, E.5
Kelsoe, G.6
Zheng, B.7
-
19
-
-
0036212917
-
Molecular mechanism of class switch recombination: linkage with somatic hypermutation
-
Honjo T, Kinoshita K, Muramatsu M (2002) Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu. Rev. Immunol. 20, 165-196.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 165-196
-
-
Honjo, T.1
Kinoshita, K.2
Muramatsu, M.3
-
20
-
-
0031448877
-
The B-cell biology of aging
-
Klinman NR, Kline GH (1997) The B-cell biology of aging. Immunol. Rev. 160, 103-114.
-
(1997)
Immunol. Rev.
, vol.160
, pp. 103-114
-
-
Klinman, N.R.1
Kline, G.H.2
-
21
-
-
0028076782
-
Improved methods of retroviral vector transduction and production for gene therapy
-
Kotani H, Newton PB III, Zhang S, Chiang YL, Otto E, Weaver L, Blaese RM, Anderson WF, McGarrity GJ (1994) Improved methods of retroviral vector transduction and production for gene therapy. Hum. Gene Ther. 5, 19-28.
-
(1994)
Hum. Gene Ther.
, vol.5
, pp. 19-28
-
-
Kotani, H.1
Newton III, P.B.2
Zhang, S.3
Chiang, Y.L.4
Otto, E.5
Weaver, L.6
Blaese, R.M.7
Anderson, W.F.8
McGarrity, G.J.9
-
22
-
-
33845431240
-
Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts
-
Lai WS, Parker JS, Grissom SF, Stumpo DJ, Blackshear PJ (2006) Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts. Mol. Cell. Biol. 26, 9196-9208.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 9196-9208
-
-
Lai, W.S.1
Parker, J.S.2
Grissom, S.F.3
Stumpo, D.J.4
Blackshear, P.J.5
-
23
-
-
0028978116
-
Repression of the immunoglobulin heavy chain 3′ enhancer by helix-loop-helix protein Id3 via a functionally important E47/E12 binding site: implications for developmental control of enhancer function
-
Meyer KB, Skogberg M, Margenfeld C, Ireland J, Pettersson S (1995) Repression of the immunoglobulin heavy chain 3′ enhancer by helix-loop-helix protein Id3 via a functionally important E47/E12 binding site: implications for developmental control of enhancer function. Eur. J. Immunol. 25, 1770-1777.
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 1770-1777
-
-
Meyer, K.B.1
Skogberg, M.2
Margenfeld, C.3
Ireland, J.4
Pettersson, S.5
-
24
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T (2000) Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102, 553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
25
-
-
0026059308
-
Repertoire diversity of antibody response to bacterial antigens in aged mice. II. Phosphorylcholine-antibody in young and aged mice differ in both VH/VL gene repertoire and in specificity
-
Nicoletti C, Borghesi-Nicoletti C, Yang XH, Schulze DH, Cerny J (1991) Repertoire diversity of antibody response to bacterial antigens in aged mice. II. Phosphorylcholine-antibody in young and aged mice differ in both VH/VL gene repertoire and in specificity. J. Immunol. 147, 2750-2755.
-
(1991)
J. Immunol.
, vol.147
, pp. 2750-2755
-
-
Nicoletti, C.1
Borghesi-Nicoletti, C.2
Yang, X.H.3
Schulze, D.H.4
Cerny, J.5
-
26
-
-
0027252520
-
Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae
-
Nicoletti C, Yang X, Cerny J (1993) Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae. J. Immunol. 150, 543-549.
-
(1993)
J. Immunol.
, vol.150
, pp. 543-549
-
-
Nicoletti, C.1
Yang, X.2
Cerny, J.3
-
27
-
-
0029913455
-
Applications of retrovirus-mediated expression cloning
-
Onishi M, Kinoshita S, Morikawa Y, Shibuya A, Phillips J, Lanier LL, Gorman DM, Nolan GP, Miyajima A, Kitamura T (1996) Applications of retrovirus-mediated expression cloning. Exp. Hematol. 24, 324-329.
-
(1996)
Exp. Hematol.
, vol.24
, pp. 324-329
-
-
Onishi, M.1
Kinoshita, S.2
Morikawa, Y.3
Shibuya, A.4
Phillips, J.5
Lanier, L.L.6
Gorman, D.M.7
Nolan, G.P.8
Miyajima, A.9
Kitamura, T.10
-
28
-
-
67349090990
-
HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation
-
Park SR, Zan H, Pal Z, Zhang J, Al-Qahtani A, Pone EJ, Xu Z, Mai T, Casali P (2009) HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation. Nat. Immunol. 10, 540-550.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 540-550
-
-
Park, S.R.1
Zan, H.2
Pal, Z.3
Zhang, J.4
Al-Qahtani, A.5
Pone, E.J.6
Xu, Z.7
Mai, T.8
Casali, P.9
-
29
-
-
0036584494
-
T cells and aging, January 2002 update
-
Pawelec G, Barnett Y, Forsey R, Frasca D, Globerson A, McLeod J, Caruso C, Franceschi C, Fulop T, Gupta S, Mariani E, Mocchegiani E, Solana R (2002) T cells and aging, January 2002 update. Front Biosci 7, d1056-d1183.
-
(2002)
Front Biosci
, vol.7
-
-
Pawelec, G.1
Barnett, Y.2
Forsey, R.3
Frasca, D.4
Globerson, A.5
McLeod, J.6
Caruso, C.7
Franceschi, C.8
Fulop, T.9
Gupta, S.10
Mariani, E.11
Mocchegiani, E.12
Solana, R.13
-
30
-
-
0027236954
-
Production of high-titer helper-free retroviruses by transient transfection
-
Pear WS, Nolan GP, Scott ML, Baltimore D (1993) Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. U S A 90, 8392-8396.
-
(1993)
Proc. Natl. Acad. Sci. U S A
, vol.90
, pp. 8392-8396
-
-
Pear, W.S.1
Nolan, G.P.2
Scott, M.L.3
Baltimore, D.4
-
31
-
-
0033571526
-
E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination
-
Quong MW, Harris DP, Swain SL, Murre C (1999) E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination. EMBO J. 18, 6307-6318.
-
(1999)
EMBO J.
, vol.18
, pp. 6307-6318
-
-
Quong, M.W.1
Harris, D.P.2
Swain, S.L.3
Murre, C.4
-
32
-
-
45249098952
-
Control of mRNA decay by phosphorylation of tristetraprolin
-
Sandler H, Stoecklin G (2008) Control of mRNA decay by phosphorylation of tristetraprolin. Biochem. Soc. Trans. 36, 491-496.
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 491-496
-
-
Sandler, H.1
Stoecklin, G.2
-
33
-
-
0038515309
-
E-proteins directly regulate expression of activation-induced deaminase in mature B cells
-
Sayegh CE, Quong MW, Agata Y, Murre C (2003) E-proteins directly regulate expression of activation-induced deaminase in mature B cells. Nat. Immunol. 4, 586-593.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 586-593
-
-
Sayegh, C.E.1
Quong, M.W.2
Agata, Y.3
Murre, C.4
-
34
-
-
0023814675
-
IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide
-
Snapper CM, Finkelman FD, Stefany D, Conrad DH, Paul WE (1988) IL-4 induces co-expression of intrinsic membrane IgG1 and IgE by murine B cells stimulated with lipopolysaccharide. J. Immunol. 141, 489-498.
-
(1988)
J. Immunol.
, vol.141
, pp. 489-498
-
-
Snapper, C.M.1
Finkelman, F.D.2
Stefany, D.3
Conrad, D.H.4
Paul, W.E.5
-
35
-
-
39049145798
-
Immunoglobulin somatic hypermutation
-
Teng G, Papavasiliou FN (2007) Immunoglobulin somatic hypermutation. Annu. Rev. Genet. 41, 107-120.
-
(2007)
Annu. Rev. Genet.
, vol.41
, pp. 107-120
-
-
Teng, G.1
Papavasiliou, F.N.2
-
36
-
-
75649096381
-
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
-
Tran TH, Nakata M, Suzuki K, Begum NA, Shinkura R, Fagarasan S, Honjo T, Nagaoka H (2010) B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers. Nat. Immunol. 11, 148-154.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 148-154
-
-
Tran, T.H.1
Nakata, M.2
Suzuki, K.3
Begum, N.A.4
Shinkura, R.5
Fagarasan, S.6
Honjo, T.7
Nagaoka, H.8
-
37
-
-
3142721218
-
Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover
-
Van der Put E, Frasca D, King AM, Blomberg BB, Riley RL (2004) Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover. J. Immunol. 173, 818-827.
-
(2004)
J. Immunol.
, vol.173
, pp. 818-827
-
-
Van der Put, E.1
Frasca, D.2
King, A.M.3
Blomberg, B.B.4
Riley, R.L.5
|