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Volumn 28, Issue 3, 1999, Pages 215-224

Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS)

Author keywords

Astrogliosis; Motoneuron; Neurodegeneration; SOD1; Spinal cord; Transgenic mice

Indexed keywords


EID: 0033485920     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(199912)28:3<215::AID-GLIA5>3.0.CO;2-C     Document Type: Article
Times cited : (135)

References (29)
  • 1
    • 0029869927 scopus 로고    scopus 로고
    • An ultrastructural study of the phagocytic activity of astrocytes in adult rat brain
    • Al-Ali SY, Al-Hussain SM. 1996. An ultrastructural study of the phagocytic activity of astrocytes in adult rat brain. J Anat (London) 188:257-262.
    • (1996) J Anat (London) , vol.188 , pp. 257-262
    • Al-Ali, S.Y.1    Al-Hussain, S.M.2
  • 2
    • 0031172081 scopus 로고    scopus 로고
    • Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: A light, confocal, and electron microscopic study using a phagocytosis-dependent labeling technique
    • Bechmann I, Nitsch R. 1997. Astrocytes and microglial cells incorporate degenerating fibers following entorhinal lesion: a light, confocal, and electron microscopic study using a phagocytosis-dependent labeling technique. Glia 20:145-154.
    • (1997) Glia , vol.20 , pp. 145-154
    • Bechmann, I.1    Nitsch, R.2
  • 3
    • 0028960506 scopus 로고
    • Amyotrophic lateral sclerosis: Recent insights from genetics and transgenic mice
    • Brown RH Jr. 1995. Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice. Cell 80:687-692.
    • (1995) Cell , vol.80 , pp. 687-692
    • Brown R.H., Jr.1
  • 6
    • 0029640071 scopus 로고
    • Superresolution three-dimensional images of fluorescence in cells with minimal light exposure
    • Carrington WA, Lynch RM, Moore ED, Isenberg G, Fogarty KE, Fay FS. 1995. Superresolution three-dimensional images of fluorescence in cells with minimal light exposure. Science 268:1483-1487.
    • (1995) Science , vol.268 , pp. 1483-1487
    • Carrington, W.A.1    Lynch, R.M.2    Moore, E.D.3    Isenberg, G.4    Fogarty, K.E.5    Fay, F.S.6
  • 7
    • 0028933344 scopus 로고
    • Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: A model of familial amyotrophic lateral sclerosis (FALS)
    • Dal Canto MC, Gurney ME. 1995. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res 676:25-40.
    • (1995) Brain Res , vol.676 , pp. 25-40
    • Dal Canto, M.C.1    Gurney, M.E.2
  • 9
    • 0027314268 scopus 로고
    • Molecular profile of reactive astrocytes -implications for their role in neurologic disease
    • Eddleston M, Mucke L. 1993. Molecular profile of reactive astrocytes - implications for their role in neurologic disease. Neuroscience 54:15-36.
    • (1993) Neuroscience , vol.54 , pp. 15-36
    • Eddleston, M.1    Mucke, L.2
  • 10
    • 0031887788 scopus 로고    scopus 로고
    • Inflammation in traumatic brain injury: Role of cytokines and chemokines
    • Ghirnikar RS, Lee YL, Eng LF. 1998. Inflammation in traumatic brain injury: role of cytokines and chemokines. Neurochem Res 23:329-340.
    • (1998) Neurochem Res , vol.23 , pp. 329-340
    • Ghirnikar, R.S.1    Lee, Y.L.2    Eng, L.F.3
  • 12
    • 0032125587 scopus 로고    scopus 로고
    • Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
    • Hall ED, Oostveen JA, Gurney ME. 1998. Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 23:249-256.
    • (1998) Glia , vol.23 , pp. 249-256
    • Hall, E.D.1    Oostveen, J.A.2    Gurney, M.E.3
  • 13
    • 0029840428 scopus 로고    scopus 로고
    • Familial amyotrophic lateral sclerosis with a two base pair deletion in superoside dismutase 1 gene: Multisystem degeneration with intracytoplasmic hyaline inclusions in astrocytes
    • Kato S, Shimoda M, Watanabe Y, Nakashima K, Takahashi K, Ohama E. 1996. Familial amyotrophic lateral sclerosis with a two base pair deletion in superoside dismutase 1 gene: multisystem degeneration with intracytoplasmic hyaline inclusions in astrocytes. J Neurophathol Exp Neurol 55:1089-1101.
    • (1996) J Neurophathol Exp Neurol , vol.55 , pp. 1089-1101
    • Kato, S.1    Shimoda, M.2    Watanabe, Y.3    Nakashima, K.4    Takahashi, K.5    Ohama, E.6
  • 14
    • 0032079517 scopus 로고    scopus 로고
    • Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
    • Kong J, Xu Z. 1998. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J Neurosci 18:3241-3250.
    • (1998) J Neurosci , vol.18 , pp. 3241-3250
    • Kong, J.1    Xu, Z.2
  • 15
    • 0032498856 scopus 로고    scopus 로고
    • Antagonistic roles of neurofilament subunits NF-H and NF-M against NF-L in shaping dendritic arborization in spinal motor neurons
    • Kong J-M, Tung VW-Y, Aghajanian J, Xu Z. 1998. Antagonistic roles of neurofilament subunits NF-H and NF-M against NF-L in shaping dendritic arborization in spinal motor neurons. J Cell Biol 140:1167-1176.
    • (1998) J Cell Biol , vol.140 , pp. 1167-1176
    • Kong, J.-M.1    Tung, V.W.-Y.2    Aghajanian, J.3    Xu, Z.4
  • 17
    • 0028218770 scopus 로고
    • Endogenous neuroprotection factors and traumatic brain injury: Mechanisms of action and implications for therapy
    • Mattson MP, Scheff SW. 1994. Endogenous neuroprotection factors and traumatic brain injury: mechanisms of action and implications for therapy. J Neurotrauma 11:3-33.
    • (1994) J Neurotrauma , vol.11 , pp. 3-33
    • Mattson, M.P.1    Scheff, S.W.2
  • 18
    • 0032146978 scopus 로고    scopus 로고
    • The importance of inflammatory mechanisms in Alzheimer disease
    • McGeer EG, McGeer PL. 1998. The importance of inflammatory mechanisms in Alzheimer disease. Exp Gerontol 33:371-378.
    • (1998) Exp Gerontol , vol.33 , pp. 371-378
    • McGeer, E.G.1    McGeer, P.L.2
  • 19
    • 0029890685 scopus 로고    scopus 로고
    • The golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu, Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease
    • Mourelatos Z, Gonatas NK, Stieber A, Gurney ME, Dal Canto MC. 1996. The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu, Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease. Proc Natl Acad Sci USA 93:5472-5477.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5472-5477
    • Mourelatos, Z.1    Gonatas, N.K.2    Stieber, A.3    Gurney, M.E.4    Dal Canto, M.C.5
  • 20
    • 0028327286 scopus 로고
    • Astrocyte responses to CNS injury
    • Norenberg MD. 1994. Astrocyte responses to CNS injury. J Neurophathol Exp Neurol 53:213-220.
    • (1994) J Neurophathol Exp Neurol , vol.53 , pp. 213-220
    • Norenberg, M.D.1
  • 21
    • 0028815433 scopus 로고
    • Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons
    • Pardo CA, Xu Z-S, Borchelt DR, Price DL, Sisodia SS, Cleveland DW. 1995. Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons. Proc Natl Acad Sci USA 92:954-958.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 954-958
    • Pardo, C.A.1    Xu, Z.-S.2    Borchelt, D.R.3    Price, D.L.4    Sisodia, S.S.5    Cleveland, D.W.6
  • 22
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis
    • Ripps ME, Huntley GW, Hof PR, Morrison JH, Gordon JW. 1995. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis. Proc Natl Acad Sci USA 92:689-693.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 24
    • 0029953341 scopus 로고    scopus 로고
    • Astrocytes, brain aging, and neurodegeneration
    • Schipper HM. 1996. Astrocytes, brain aging, and neurodegeneration. Neurobiol Aging 17:467-480.
    • (1996) Neurobiol Aging , vol.17 , pp. 467-480
    • Schipper, H.M.1
  • 25
    • 0002918293 scopus 로고
    • Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ
    • Sternberger LA, Sternberger NH. 1983. Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ. Proc Natl Acad Sci USA 80:6126-130.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 6126-6130
    • Sternberger, L.A.1    Sternberger, N.H.2
  • 26
    • 0031897688 scopus 로고    scopus 로고
    • Neuronal death: Is there a role for astrocytes?
    • Tacconi MT. 1998. Neuronal death: is there a role for astrocytes? Neurochem Res 23:759-765.
    • (1998) Neurochem Res , vol.23 , pp. 759-765
    • Tacconi, M.T.1
  • 27
    • 0029966363 scopus 로고    scopus 로고
    • Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
    • Tu PH, Raju P, Robinson KA, Gurney ME, Trojanowski JQ, Lee VMY. 1996. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc Natl Acad Sci USA 93:3155-3160.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3155-3160
    • Tu, P.H.1    Raju, P.2    Robinson, K.A.3    Gurney, M.E.4    Trojanowski, J.Q.5    Lee, V.M.Y.6
  • 28
    • 0031465419 scopus 로고    scopus 로고
    • Antioxidant defense of the brain: A role for astrocytes
    • Wilson JX. 1997. Antioxidant defense of the brain: a role for astrocytes. Can J Physiol Pharmacol 75:1149-1163.
    • (1997) Can J Physiol Pharmacol , vol.75 , pp. 1149-1163
    • Wilson, J.X.1
  • 29
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
    • Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. 1995. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14:1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.A.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.