Elevation of the Hsp70 chaperone does not effect toxicity in mouse models of familial amyotrophic lateral sclerosis

Journal of Neurochemistry

Volumn 93, Issue 4, 2005, Pages 875-882

  Liu, Jian ^a,c   Shinobu, Leslie A ^b   Ward, Christopher M ^a   Young, Darren ^a   Cleveland, Don W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

Author keywords

Heat shock protein 70; Motor neuron death; Neurodegenerative disease; Protein aggregates; Stress response

Indexed keywords

CHAPERONE; COPPER ZINC SUPEROXIDE DISMUTASE; GENE PRODUCT; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; FAMILIAL DISEASE; GENE MUTATION; IMMUNOCYTOCHEMISTRY; ISCHEMIA; MOTONEURON; MOUSE; NEUROPATHOLOGY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRESS; TRANSGENIC MOUSE;

AGE FACTORS; AGE OF ONSET; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BODY WEIGHT; BRAIN; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; PSYCHOMOTOR PERFORMANCE; SPINAL CORD; SUPEROXIDE DISMUTASE;

MUS MUSCULUS;

EID: 18844444198     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03054.x     Document Type: Article

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