Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS

Journal of Neuroscience

Volumn 26, Issue 34, 2006, Pages 8774-8786

  Gould, Thomas W ^a   Buss, Robert R ^a   Vinsant, Sharon ^a   Prevette, David ^a   Sun, Woong ^b   Knudson, C Michael ^c   Milligan, Carol E ^a   Oppenheim, Ronald W ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b Korea University College of Medicine   (South Korea)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

ALS; Axonopathy; Cell death; Denervation; Motoneuron; Synaptic

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MUTANT PROTEIN; PROTEIN BAX;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CELL DEATH; CELL VACUOLE; CONTROLLED STUDY; FEMALE; GLIOSIS; LIFESPAN; MALE; MITOCHONDRION; MOTONEURON; MOTOR DYSFUNCTION; MOUSE; MUSCLE DENERVATION; MYELINATED NERVE; NERVE FIBER; NEUROMUSCULAR SYNAPSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; SCHWANN CELL; SPINAL CORD; SURVIVAL; TRANSGENIC MOUSE; VENTRAL ROOT;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AXONS; BCL-2-ASSOCIATED X PROTEIN; CELL DEATH; CELL SURVIVAL; DEMYELINATING DISEASES; DENERVATION; GENE DELETION; GLIOSIS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MOTOR NEURONS; MOVEMENT; MUTATION; NEUROMUSCULAR JUNCTION; PRESYNAPTIC TERMINALS; SCHWANN CELLS; SPINAL NERVE ROOTS; SUPEROXIDE DISMUTASE; TIME FACTORS; VACUOLES;

EID: 33748261830     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2315-06.2006     Document Type: Article

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