ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 49, 2010, Pages 21146-21151

  Li, Quan ^a   Velde, Christine Vande ^b,c   Israelson, Adrian ^b   Xie, Jing ^e   Bailey, Aaron O ^d   Dong, Meng Qui ^d   Chun, Seung Joo ^a   Roy, Tamal ^b   Winer, Leah ^a   Yates, John R ^d   Capaldi, Roderick A ^e   Cleveland, Don W ^b   Miller, Timothy M ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e MitoSciences Inc   (United States)

Author keywords

Amyotrophic; Motor neuron disease; Neurodegenerative disease; Proteomic

Indexed keywords

ALPHA SYNUCLEIN; COPPER ZINC SUPEROXIDE DISMUTASE; MITOCHONDRIAL PROTEIN; MUTANT PROTEIN; RECOMBINANT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL TISSUE; ARTICLE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; PROTEIN TRANSPORT; RAT; SPINAL CORD;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; LIVER; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; PROTEIN TRANSPORT; PROTEOMICS; RATS; SPINAL CORD; SUPEROXIDE DISMUTASE;

MUS; RATTUS;

EID: 78650503526     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1014862107     Document Type: Article

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