-
1
-
-
0025230372
-
Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line
-
Drivas GT, Shih A, Coutavas E, Rush MG, D'Eustachio P. Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line. Mol Cell Biol 1990; 10: 1793–1798.
-
(1990)
Mol Cell Biol
, vol.10
, pp. 1793-1798
-
-
Drivas, G.T.1
Shih, A.2
Coutavas, E.3
Rush, M.G.4
D'Eustachio, P.5
-
2
-
-
0027389003
-
Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis
-
Ren M, Drivas G, D'Eustachio P, Rush MG. Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis. J Cell Biol 1993; 120: 313–323.
-
(1993)
J Cell Biol
, vol.120
, pp. 313-323
-
-
Ren, M.1
Drivas, G.2
D'Eustachio, P.3
Rush, M.G.4
-
3
-
-
0018128369
-
Premature of chromosome condensation in a ts DNA-mutant of BHK cells
-
Nishimoto T, Eilen E, Basilico C. Premature of chromosome condensation in a ts DNA-mutant of BHK cells. Cell 1978; 15: 475–483.
-
(1978)
Cell
, vol.15
, pp. 475-483
-
-
Nishimoto, T.1
Eilen, E.2
Basilico, C.3
-
4
-
-
0024445582
-
The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA
-
Ohtsubo M, Okazaki H, Nishimoto T. The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA. J Cell Biol 1989; 109: 1389–1397.
-
(1989)
J Cell Biol
, vol.109
, pp. 1389-1397
-
-
Ohtsubo, M.1
Okazaki, H.2
Nishimoto, T.3
-
5
-
-
0035947299
-
Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B
-
Nemergut ME, Mizzen CA, Stukenberg T, Allis CD, Macara IG. Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B. Science 2001; 292: 1540–1543.
-
(2001)
Science
, vol.292
, pp. 1540-1543
-
-
Nemergut, M.E.1
Mizzen, C.A.2
Stukenberg, T.3
Allis, C.D.4
Macara, I.G.5
-
6
-
-
0028222104
-
RanGAP1 induces GTPase activity of nuclear Ras-related Ran
-
Bischoff FR, Klebe C, Kretschmer J, Wittinghofer A, Ponstingl H. RanGAP1 induces GTPase activity of nuclear Ras-related Ran. Proc Natl Acad Sci USA 1994; 91: 2587–2591.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2587-2591
-
-
Bischoff, F.R.1
Klebe, C.2
Kretschmer, J.3
Wittinghofer, A.4
Ponstingl, H.5
-
7
-
-
0025819957
-
Characterization of the opposite-strand genes from the mouse bidirectionally transcribed HTF9 locus
-
Bressan A, Somma MP, Lewis J, Santolamazza C, Copeland NG, Gilbert DJ, Jenkins NA, Lavia P. Characterization of the opposite-strand genes from the mouse bidirectionally transcribed HTF9 locus. Gene 1991; 103: 201–209.
-
(1991)
Gene
, vol.103
, pp. 201-209
-
-
Bressan, A.1
Somma, M.P.2
Lewis, J.3
Santolamazza, C.4
Copeland, N.G.5
Gilbert, D.J.6
Jenkins, N.A.7
Lavia, P.8
-
8
-
-
0027732054
-
Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4
-
Coutavas E, Ren M, Oppenheim JD, D'Eustachio P, Rush MG. Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4. Nature 1993; 366: 585–587.
-
(1993)
Nature
, vol.366
, pp. 585-587
-
-
Coutavas, E.1
Ren, M.2
Oppenheim, J.D.3
D'Eustachio, P.4
Rush, M.G.5
-
9
-
-
0029070074
-
Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region
-
Wu J, Matunis MJ, Kraemer D, Blobel G, Coutavas E. Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region. J Biol Chem 1995; 270: 14209–14213.
-
(1995)
J Biol Chem
, vol.270
, pp. 14209-14213
-
-
Wu, J.1
Matunis, M.J.2
Kraemer, D.3
Blobel, G.4
Coutavas, E.5
-
10
-
-
0029032954
-
A giant nucleopore protein that binds Ran/TC4
-
Yokoyama N, Hayashi N, Seki T, Panté N, Ohba T, Nishii K, Kuma K, Hayashida T, Miyata T, Aebi U, Fukui M, Nishimoto T. A giant nucleopore protein that binds Ran/TC4. Nature 1995; 376: 184–188.
-
(1995)
Nature
, vol.376
, pp. 184-188
-
-
Yokoyama, N.1
Hayashi, N.2
Seki, T.3
Panté, N.4
Ohba, T.5
Nishii, K.6
Kuma, K.7
Hayashida, T.8
Miyata, T.9
Aebi, U.10
Fukui, M.11
Nishimoto, T.12
-
11
-
-
79960912049
-
Nuclear import by karyopherin-βs: recognition and inhibition
-
Chook YM, Süel KE. Nuclear import by karyopherin-βs: recognition and inhibition. Biochim Biophys Acta 2011; 1813: 1593–1606.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1593-1606
-
-
Chook, Y.M.1
Süel, K.E.2
-
12
-
-
8644262258
-
Importin β: conducting a much larger cellular symphony
-
Harel A, Forbes DJ. Importin β: conducting a much larger cellular symphony. Mol Cell 2004; 16: 319–330.
-
(2004)
Mol Cell
, vol.16
, pp. 319-330
-
-
Harel, A.1
Forbes, D.J.2
-
13
-
-
0021269089
-
Sequence requirements for nuclear location of simian virus 40 large-T antigen
-
Kalderon D, Richardson WD, Markham AF, Smith AE. Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature 1984; 311: 33–38.
-
(1984)
Nature
, vol.311
, pp. 33-38
-
-
Kalderon, D.1
Richardson, W.D.2
Markham, A.F.3
Smith, A.E.4
-
14
-
-
0021716406
-
A short amino acid sequence able to specify nuclear location
-
Kalderon D, Roberts BL, Richardson WD, Smith AE. A short amino acid sequence able to specify nuclear location. Cell 1984; 39: 499–509.
-
(1984)
Cell
, vol.39
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
15
-
-
0026078249
-
Two inter-dependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence
-
Robbins J, Dilworth SM, Laskey RA, Dingwall C. Two inter-dependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 1991; 64: 615–623.
-
(1991)
Cell
, vol.64
, pp. 615-623
-
-
Robbins, J.1
Dilworth, S.M.2
Laskey, R.A.3
Dingwall, C.4
-
16
-
-
0028988731
-
Identification of hSRP1 α as a functional receptor for nuclear localization sequences
-
Weis K, Mattaj IW, Lamond AI. Identification of hSRP1 α as a functional receptor for nuclear localization sequences. Science 1995; 268: 1049–1053.
-
(1995)
Science
, vol.268
, pp. 1049-1053
-
-
Weis, K.1
Mattaj, I.W.2
Lamond, A.I.3
-
17
-
-
0029130168
-
Identification of a signal for rapid export of proteins from the nucleus
-
Wen W, Meinkoth JL, Tsien RY, Taylor SS. Identification of a signal for rapid export of proteins from the nucleus. Cell 1995; 82: 463–473.
-
(1995)
Cell
, vol.82
, pp. 463-473
-
-
Wen, W.1
Meinkoth, J.L.2
Tsien, R.Y.3
Taylor, S.S.4
-
18
-
-
0029130169
-
The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
-
Fischer U, Huber J, Boelens WC, Mattaj IW, Lührmann R. The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell 1995; 82: 475–483.
-
(1995)
Cell
, vol.82
, pp. 475-483
-
-
Fischer, U.1
Huber, J.2
Boelens, W.C.3
Mattaj, I.W.4
Lührmann, R.5
-
19
-
-
0027937653
-
Isolation of a protein that is essential for the first step of nuclear protein import
-
Görlich D, Prehn S, Laskey RA, Hartmann E. Isolation of a protein that is essential for the first step of nuclear protein import. Cell 1994; 79: 767–778.
-
(1994)
Cell
, vol.79
, pp. 767-778
-
-
Görlich, D.1
Prehn, S.2
Laskey, R.A.3
Hartmann, E.4
-
20
-
-
0029093824
-
In vivo evidence for involvement of a 58 kDa component of nuclear pore-targeting complex in nuclear protein import
-
Imamoto N, Shimamoto T, Takao T, Tachibana T, Kose S, Matsubae M, Sekimoto T, Shimonishi Y, Yoneda Y. In vivo evidence for involvement of a 58 kDa component of nuclear pore-targeting complex in nuclear protein import. EMBO J 1995; 14: 3617–3626.
-
(1995)
EMBO J
, vol.14
, pp. 3617-3626
-
-
Imamoto, N.1
Shimamoto, T.2
Takao, T.3
Tachibana, T.4
Kose, S.5
Matsubae, M.6
Sekimoto, T.7
Shimonishi, Y.8
Yoneda, Y.9
-
21
-
-
0029132794
-
The nuclear pore-targeting complex binds to nuclear pores after association with a karyophile
-
Imamoto N, Shimamoto T, Kose S, Takao T, Tachibana T, Matsubae M, Sekimoto T, Shimonishi Y, Yoneda Y. The nuclear pore-targeting complex binds to nuclear pores after association with a karyophile. FEBS Lett 1995; 368: 415–419.
-
(1995)
FEBS Lett
, vol.368
, pp. 415-419
-
-
Imamoto, N.1
Shimamoto, T.2
Kose, S.3
Takao, T.4
Tachibana, T.5
Matsubae, M.6
Sekimoto, T.7
Shimonishi, Y.8
Yoneda, Y.9
-
22
-
-
0028962511
-
Previously identified protein of uncertain function is karyopherin α and together with karyopherin β docks import substrate at nuclear pore complexes
-
Moroianu J, Blobel G, Radu A. Previously identified protein of uncertain function is karyopherin α and together with karyopherin β docks import substrate at nuclear pore complexes. Proc Natl Acad Sci USA 1995; 92: 2008–2011.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2008-2011
-
-
Moroianu, J.1
Blobel, G.2
Radu, A.3
-
23
-
-
0029278621
-
Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope
-
Görlich D, Kostka S, Kraft R, Dingwall C, Laskey RA, Hartmann E, Prehn S. Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope. Curr Biol 1995; 5: 383–392.
-
(1995)
Curr Biol
, vol.5
, pp. 383-392
-
-
Görlich, D.1
Kostka, S.2
Kraft, R.3
Dingwall, C.4
Laskey, R.A.5
Hartmann, E.6
Prehn, S.7
-
24
-
-
0029115837
-
Sequence and characterization of cytoplasmic nuclear protein import factor p97
-
Chi NC, Adam EJ, Adam SA. Sequence and characterization of cytoplasmic nuclear protein import factor p97. J Cell Biol 1995; 130: 265–274.
-
(1995)
J Cell Biol
, vol.130
, pp. 265-274
-
-
Chi, N.C.1
Adam, E.J.2
Adam, S.A.3
-
25
-
-
0342276108
-
Export of importin α from the nucleus is mediated by a specific nuclear transport factor
-
Kutay U, Bischoff FR, Kostka S, Kraft R, Görlich D. Export of importin α from the nucleus is mediated by a specific nuclear transport factor. Cell 1997; 90: 1061–1071.
-
(1997)
Cell
, vol.90
, pp. 1061-1071
-
-
Kutay, U.1
Bischoff, F.R.2
Kostka, S.3
Kraft, R.4
Görlich, D.5
-
26
-
-
0032555365
-
Cse1p functions as the nuclear export receptor for importin α in yeast
-
Künzler M, Hurt EC. Cse1p functions as the nuclear export receptor for importin α in yeast. FEBS Lett 1998; 433: 185–190.
-
(1998)
FEBS Lett
, vol.433
, pp. 185-190
-
-
Künzler, M.1
Hurt, E.C.2
-
28
-
-
0032567443
-
Cse1p is required for export of Srp1p/importin-α from the nucleus in Saccharomyces cerevisiae
-
Hood JK, Silver PA. Cse1p is required for export of Srp1p/importin-α from the nucleus in Saccharomyces cerevisiae. J Biol Chem 1998; 273: 35142–35146.
-
(1998)
J Biol Chem
, vol.273
, pp. 35142-35146
-
-
Hood, J.K.1
Silver, P.A.2
-
29
-
-
0028889656
-
Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1
-
Brinkmann U, Brinkmann E, Gallo M, Pastan I. Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1. Proc Natl Acad Sci USA 1995; 92: 10427–10431.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10427-10431
-
-
Brinkmann, U.1
Brinkmann, E.2
Gallo, M.3
Pastan, I.4
-
30
-
-
0032538803
-
NTF2 mediates nuclear import of Ran
-
Ribbeck K, Lipowsky G, Kent HM, Stewart M, Görlich D. NTF2 mediates nuclear import of Ran. EMBO J 1998; 17: 6587–6598.
-
(1998)
EMBO J
, vol.17
, pp. 6587-6598
-
-
Ribbeck, K.1
Lipowsky, G.2
Kent, H.M.3
Stewart, M.4
Görlich, D.5
-
31
-
-
0023631970
-
Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells
-
Yoneda Y, Imamoto-Sonobe N, Yamaizumi M, Uchida T. Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells. Exp Cell Res 1987; 173: 586–595.
-
(1987)
Exp Cell Res
, vol.173
, pp. 586-595
-
-
Yoneda, Y.1
Imamoto-Sonobe, N.2
Yamaizumi, M.3
Uchida, T.4
-
32
-
-
79959692369
-
Importazole, a small molecule inhibitor of the transport receptor importin-β
-
Soderholm JF, Bird SL, Kalab P, Sampathkumar Y, Hasegawa K, Uehara-Bingen M, Weis K, Heald R. Importazole, a small molecule inhibitor of the transport receptor importin-β. ACS Chem Biol 2011; 6: 700–708.
-
(2011)
ACS Chem Biol
, vol.6
, pp. 700-708
-
-
Soderholm, J.F.1
Bird, S.L.2
Kalab, P.3
Sampathkumar, Y.4
Hasegawa, K.5
Uehara-Bingen, M.6
Weis, K.7
Heald, R.8
-
33
-
-
0030985459
-
Exportin 1 (Crm1p) is an essential nuclear export factor
-
Stade K, Ford CS, Guthrie C, Weis K. Exportin 1 (Crm1p) is an essential nuclear export factor. Cell 1997; 90: 1041–1050.
-
(1997)
Cell
, vol.90
, pp. 1041-1050
-
-
Stade, K.1
Ford, C.S.2
Guthrie, C.3
Weis, K.4
-
34
-
-
0030924190
-
CRM1 is an export receptor for leucine-rich nuclear export signals
-
Fornerod M, Ohno M, Yoshida M, Mattaj IW. CRM1 is an export receptor for leucine-rich nuclear export signals. Cell 1997; 90: 1051–1060.
-
(1997)
Cell
, vol.90
, pp. 1051-1060
-
-
Fornerod, M.1
Ohno, M.2
Yoshida, M.3
Mattaj, I.W.4
-
35
-
-
0031260540
-
The importin-β family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export
-
Neville M, Stutz F, Lee L, Davis LI, Rosbash M. The importin-β family member Crm1p bridges the interaction between Rev and the nuclear pore complex during nuclear export. Curr Biol 1997; 7: 767–775.
-
(1997)
Curr Biol
, vol.7
, pp. 767-775
-
-
Neville, M.1
Stutz, F.2
Lee, L.3
Davis, L.I.4
Rosbash, M.5
-
36
-
-
0030748907
-
Evidence for a role of CRM1 in signal-mediated nuclear protein export
-
Ossareh-Nazari B, Bachelerie F, Dargemont C. Evidence for a role of CRM1 in signal-mediated nuclear protein export. Science 1997; 278: 141–144.
-
(1997)
Science
, vol.278
, pp. 141-144
-
-
Ossareh-Nazari, B.1
Bachelerie, F.2
Dargemont, C.3
-
37
-
-
0030831534
-
CRM1 is responsible for intracellular transport mediated by the nuclear export signal
-
Fukuda M, Asano S, Nakamura T, Adachi M, Yoshida M, Yanagida M, Nishida E. CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Nature 1997; 390: 308–311.
-
(1997)
Nature
, vol.390
, pp. 308-311
-
-
Fukuda, M.1
Asano, S.2
Nakamura, T.3
Adachi, M.4
Yoshida, M.5
Yanagida, M.6
Nishida, E.7
-
38
-
-
0034760338
-
RanBP3 influences interactions between CRM1 and its nuclear protein export substrates
-
Englmeier L, Fornerod M, Bischoff FR, Petosa C, Mattaj IW, Kutay U. RanBP3 influences interactions between CRM1 and its nuclear protein export substrates. EMBO Rep 2001; 2: 926–932.
-
(2001)
EMBO Rep
, vol.2
, pp. 926-932
-
-
Englmeier, L.1
Fornerod, M.2
Bischoff, F.R.3
Petosa, C.4
Mattaj, I.W.5
Kutay, U.6
-
39
-
-
0035954439
-
Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export
-
Lindsay ME, Holaska JM, Welch K, Paschal BM, Macara IG. Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export. J Cell Biol 2001; 153: 1391–1402.
-
(2001)
J Cell Biol
, vol.153
, pp. 1391-1402
-
-
Lindsay, M.E.1
Holaska, J.M.2
Welch, K.3
Paschal, B.M.4
Macara, I.G.5
-
40
-
-
0037124071
-
Ranbinding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor
-
Nemergut ME, Lindsay ME, Brownawell AM, Macara IG. Ranbinding protein 3 links Crm1 to the Ran guanine nucleotide exchange factor. J Biol Chem 2001; 277: 17385–17388.
-
(2001)
J Biol Chem
, vol.277
, pp. 17385-17388
-
-
Nemergut, M.E.1
Lindsay, M.E.2
Brownawell, A.M.3
Macara, I.G.4
-
41
-
-
0032146749
-
Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1
-
Kudo N, Wolff B, Sekimoto T, Schreiner EP, Yoneda Y, Yanagida M, Horinouchi S, Yoshida M. Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Exp Cell Res 1998; 242: 540–547.
-
(1998)
Exp Cell Res
, vol.242
, pp. 540-547
-
-
Kudo, N.1
Wolff, B.2
Sekimoto, T.3
Schreiner, E.P.4
Yoneda, Y.5
Yanagida, M.6
Horinouchi, S.7
Yoshida, M.8
-
42
-
-
0037268889
-
Nucleo-cytoplasmic transport of proteins as a target for therapeutic drugs
-
Yashiroda Y, Yoshida M. Nucleo-cytoplasmic transport of proteins as a target for therapeutic drugs. Curr Med Chem 2003; 10: 741–748.
-
(2003)
Curr Med Chem
, vol.10
, pp. 741-748
-
-
Yashiroda, Y.1
Yoshida, M.2
-
43
-
-
0032910953
-
β-Catenin can be transported into the nucleus in a Ran-unassisted manner
-
Yokoya F, Imamoto N, Tachibana T, Yoneda Y. β-Catenin can be transported into the nucleus in a Ran-unassisted manner. Mol Biol Cell 1999; 10: 1119–1131.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1119-1131
-
-
Yokoya, F.1
Imamoto, N.2
Tachibana, T.3
Yoneda, Y.4
-
44
-
-
0030726210
-
Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complex
-
Kose S, Imamoto N, Tachibana T, Shimamoto T, Yoneda Y. Ran-unassisted nuclear migration of a 97-kD component of nuclear pore-targeting complex. J Cell Biol 1997; 139: 841–849.
-
(1997)
J Cell Biol
, vol.139
, pp. 841-849
-
-
Kose, S.1
Imamoto, N.2
Tachibana, T.3
Shimamoto, T.4
Yoneda, Y.5
-
45
-
-
0035907305
-
Nuclear import of the U1A splicesome protein is mediated by importin α/β and Ran in living mammalian cells
-
Hieda M, Tachibana T, Fukumoto M, Yoneda Y. Nuclear import of the U1A splicesome protein is mediated by importin α/β and Ran in living mammalian cells. J Biol Chem 2001; 276: 16824–16832.
-
(2001)
J Biol Chem
, vol.276
, pp. 16824-16832
-
-
Hieda, M.1
Tachibana, T.2
Fukumoto, M.3
Yoneda, Y.4
-
46
-
-
0034707624
-
An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B” spliceome proteins
-
Hetzer M, Mattaj IW. An ATP-dependent, Ran-independent mechanism for nuclear import of the U1A and U2B” spliceome proteins. J Cell Biol 2000; 148: 293–303.
-
(2000)
J Cell Biol
, vol.148
, pp. 293-303
-
-
Hetzer, M.1
Mattaj, I.W.2
-
47
-
-
0036846540
-
Importin α can migrate into the nucleus in an importin β-and Ran-independent manner
-
Miyamoto Y, Hieda M, Harreman MT, Fukumoto M, Saiwaki T, Hodel AE, Corbett AH, Yoneda Y. Importin α can migrate into the nucleus in an importin β-and Ran-independent manner. EMBO J 2002; 21: 5833–5842.
-
(2002)
EMBO J
, vol.21
, pp. 5833-5842
-
-
Miyamoto, Y.1
Hieda, M.2
Harreman, M.T.3
Fukumoto, M.4
Saiwaki, T.5
Hodel, A.E.6
Corbett, A.H.7
Yoneda, Y.8
-
48
-
-
0033528994
-
The ran GTPase regulates mitotic spindle assembly
-
Kalab P, Pu RT, Dasso M. The ran GTPase regulates mitotic spindle assembly. Curr Biol 1999; 9: 481–484.
-
(1999)
Curr Biol
, vol.9
, pp. 481-484
-
-
Kalab, P.1
Pu, R.T.2
Dasso, M.3
-
49
-
-
0033591386
-
Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran
-
Ohba T, Nakamura M, Nishitani H, Nishimoto T. Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran. Science 1999; 284: 1356–1358.
-
(1999)
Science
, vol.284
, pp. 1356-1358
-
-
Ohba, T.1
Nakamura, M.2
Nishitani, H.3
Nishimoto, T.4
-
50
-
-
0033591373
-
Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran
-
Wilde A, Zheng Y. Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. Science 1999; 284: 1359–1362.
-
(1999)
Science
, vol.284
, pp. 1359-1362
-
-
Wilde, A.1
Zheng, Y.2
-
51
-
-
0032814745
-
Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts
-
Zhang C, Hughes M, Clarke PR. Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts. J Cell Sci 1999; 112: 2453–2461.
-
(1999)
J Cell Sci
, vol.112
, pp. 2453-2461
-
-
Zhang, C.1
Hughes, M.2
Clarke, P.R.3
-
52
-
-
0033536178
-
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation
-
Carazo-Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 1999; 400: 178–181.
-
(1999)
Nature
, vol.400
, pp. 178-181
-
-
Carazo-Salas, R.E.1
Guarguaglini, G.2
Gruss, O.J.3
Segref, A.4
Karsenti, E.5
Mattaj, I.W.6
-
53
-
-
0037192461
-
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
-
Kalab P, Weis K, Heald R. Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. Science 2002; 294: 2452–2456.
-
(2002)
Science
, vol.294
, pp. 2452-2456
-
-
Kalab, P.1
Weis, K.2
Heald, R.3
-
54
-
-
33645452992
-
Analysis of a RanGTP-regulated gradient in mitotic somatic cells
-
Kalab P, Pralle A, Isacoff EY, Heald R, Weis K. Analysis of a RanGTP-regulated gradient in mitotic somatic cells. Nature 2006; 440: 697–701.
-
(2006)
Nature
, vol.440
, pp. 697-701
-
-
Kalab, P.1
Pralle, A.2
Isacoff, E.Y.3
Heald, R.4
Weis, K.5
-
55
-
-
17744380396
-
Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity
-
Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW. Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity. Cell 2001; 104: 83–93.
-
(2001)
Cell
, vol.104
, pp. 83-93
-
-
Gruss, O.J.1
Carazo-Salas, R.E.2
Schatz, C.A.3
Guarguaglini, G.4
Kast, J.5
Wilm, M.6
Le Bot, N.7
Vernos, I.8
Karsenti, E.9
Mattaj, I.W.10
-
56
-
-
0035951480
-
Role of importin-β in coupling Ran to downstream targets in microtubule assembly
-
Wiese C, Wilde A, Moore MS, Adam SA, Merdes A, Zheng Y. Role of importin-β in coupling Ran to downstream targets in microtubule assembly. Science 2001; 291: 653–656.
-
(2001)
Science
, vol.291
, pp. 653-656
-
-
Wiese, C.1
Wilde, A.2
Moore, M.S.3
Adam, S.A.4
Merdes, A.5
Zheng, Y.6
-
57
-
-
0035846901
-
Importin β is a mitotic target of the small GTPase Ran in spindle assembly
-
Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K. Importin β is a mitotic target of the small GTPase Ran in spindle assembly. Cell 2001; 104: 95–106.
-
(2001)
Cell
, vol.104
, pp. 95-106
-
-
Nachury, M.V.1
Maresca, T.J.2
Salmon, W.C.3
Waterman-Storer, C.M.4
Heald, R.5
Weis, K.6
-
58
-
-
0034717818
-
TPX2, A novel Xenopus MAP involved in spindle pole organization
-
Wittmann T, Wilm M, Karsenti E, Vernos I. TPX2, A novel Xenopus MAP involved in spindle pole organization. J Cell Biol 2000; 149: 1405–1418.
-
(2000)
J Cell Biol
, vol.149
, pp. 1405-1418
-
-
Wittmann, T.1
Wilm, M.2
Karsenti, E.3
Vernos, I.4
-
59
-
-
0037446847
-
A novel mechanism for activation of the protein kinase Aurora A
-
Eyers PA, Erikson E, Chen LG, Maller JL. A novel mechanism for activation of the protein kinase Aurora A. Curr Biol 2003; 13: 691–697.
-
(2003)
Curr Biol
, vol.13
, pp. 691-697
-
-
Eyers, P.A.1
Erikson, E.2
Chen, L.G.3
Maller, J.L.4
-
60
-
-
0037341906
-
A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly
-
Tsai MY, Wiese C, Cao K, Martin O, Donovan P, Ruderman J, Prigent C, Zheng Y. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat Cell Biol 2003; 5: 242–248.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 242-248
-
-
Tsai, M.Y.1
Wiese, C.2
Cao, K.3
Martin, O.4
Donovan, P.5
Ruderman, J.6
Prigent, C.7
Zheng, Y.8
-
61
-
-
0348013019
-
Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation
-
Trieselmann N, Armstrong S, Rauw J, Wilde A. Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation. J Cell Sci 2003; 116: 4791–4798.
-
(2003)
J Cell Sci
, vol.116
, pp. 4791-4798
-
-
Trieselmann, N.1
Armstrong, S.2
Rauw, J.3
Wilde, A.4
-
62
-
-
33646061361
-
HURP is a Ran-importin β-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes
-
Sillé HH, Nagel S, Körner R, Nigg EA. HURP is a Ran-importin β-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes. Curr Biol 2006; 16: 731–742.
-
(2006)
Curr Biol
, vol.16
, pp. 731-742
-
-
Sillé, H.H.1
Nagel, S.2
Körner, R.3
Nigg, E.A.4
-
63
-
-
33646024346
-
HURP is part of a Ran-dependent complex involved in spindle formation
-
Koffa MD, Casanova CM, Santarella R, Köcher T, Wilm M, Mattaj IW. HURP is part of a Ran-dependent complex involved in spindle formation. Curr Biol 2006; 16: 743–754.
-
(2006)
Curr Biol
, vol.16
, pp. 743-754
-
-
Koffa, M.D.1
Casanova, C.M.2
Santarella, R.3
Köcher, T.4
Wilm, M.5
Mattaj, I.W.6
-
64
-
-
17444411537
-
A Rael-containing ribonucleoprotein complex is required for mitotic spindle assembly
-
Blower MD, Nachury M, Heald R, Weis K. A Rael-containing ribonucleoprotein complex is required for mitotic spindle assembly. Cell 2005; 121: 223–234.
-
(2005)
Cell
, vol.121
, pp. 223-234
-
-
Blower, M.D.1
Nachury, M.2
Heald, R.3
Weis, K.4
-
65
-
-
33744757357
-
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules
-
Ribbeck K, Groen AC, Santarella R, Bohnsack MT, Raemaekers T, Köcher T, Gentzel M, Görlich D, Wilm M, Carmeliet G, Mitchison TJ, Ellenberg J, Hoenger A, Mattaj IW. NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell 2006; 17: 246–260.
-
(2006)
Mol Biol Cell
, vol.17
, pp. 246-260
-
-
Ribbeck, K.1
Groen, A.C.2
Santarella, R.3
Bohnsack, M.T.4
Raemaekers, T.5
Köcher, T.6
Gentzel, M.7
Görlich, D.8
Wilm, M.9
Carmeliet, G.10
Mitchison, T.J.11
Ellenberg, J.12
Hoenger, A.13
Mattaj, I.W.14
-
66
-
-
39049089174
-
Importin-β and the small guanosine triphosphatase Ran mediate chromosome loading of the human chromokinesin Kid
-
Tahara K, Takagi M, Ohsugi M, Sone T, Nishiumi F, Maeshima K, Horiuchi Y, Tokai-Nishizumi N, Imamoto F, Yamamoto T, Kose S, Imamoto N. Importin-β and the small guanosine triphosphatase Ran mediate chromosome loading of the human chromokinesin Kid. J Cell Biol 2008; 180: 493–506.
-
(2008)
J Cell Biol
, vol.180
, pp. 493-506
-
-
Tahara, K.1
Takagi, M.2
Ohsugi, M.3
Sone, T.4
Nishiumi, F.5
Maeshima, K.6
Horiuchi, Y.7
Tokai-Nishizumi, N.8
Imamoto, F.9
Yamamoto, T.10
Kose, S.11
Imamoto, N.12
-
67
-
-
40849119789
-
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
-
Yokoyama H, Gruss OJ, Rybina S, Caudron M, Schelder M, Wilm M, Mattaj IW, Karsenti E. Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate. J Cell Biol 2008; 180: 867–875.
-
(2008)
J Cell Biol
, vol.180
, pp. 867-875
-
-
Yokoyama, H.1
Gruss, O.J.2
Rybina, S.3
Caudron, M.4
Schelder, M.5
Wilm, M.6
Mattaj, I.W.7
Karsenti, E.8
-
68
-
-
0346099347
-
Importin α/β and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal
-
Ems-McClung SC, Zheng Y, Walczak CE. Importin α/β and Ran-GTP regulate XCTK2 microtubule binding through a bipartite nuclear localization signal. Mol Biol Cell 2004; 15: 46–57.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 46-57
-
-
Ems-McClung, S.C.1
Zheng, Y.2
Walczak, C.E.3
-
69
-
-
77951949971
-
Regulated degradation of spindle assembly factors by the anaphase-promoting complex
-
Song L, Rape M. Regulated degradation of spindle assembly factors by the anaphase-promoting complex. Mol Cell 2010; 38: 369–382.
-
(2010)
Mol Cell
, vol.38
, pp. 369-382
-
-
Song, L.1
Rape, M.2
-
70
-
-
0034717035
-
Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts
-
Zhang C, Clarke PR. Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts. Science 2000; 288: 1429–1432.
-
(2000)
Science
, vol.288
, pp. 1429-1432
-
-
Zhang, C.1
Clarke, P.R.2
-
71
-
-
0033638971
-
GTP hydrolysis by Ran is required for nuclear envelope assembly
-
Hetzer M, Bilbao-Cortés D, Walther TC, Gruss OJ, Mattaj IW. GTP hydrolysis by Ran is required for nuclear envelope assembly. Mol Cell 2000; 5: 1013–1024.
-
(2000)
Mol Cell
, vol.5
, pp. 1013-1024
-
-
Hetzer, M.1
Bilbao-Cortés, D.2
Walther, T.C.3
Gruss, O.J.4
Mattaj, I.W.5
-
72
-
-
0344670185
-
The Ran GTPase cycle is required for yeast nuclear pore complex assembly
-
Ryan KJ, McCaffery JM, Wente SR. The Ran GTPase cycle is required for yeast nuclear pore complex assembly. J Cell Biol 2003; 160: 1041–1053.
-
(2003)
J Cell Biol
, vol.160
, pp. 1041-1053
-
-
Ryan, K.J.1
McCaffery, J.M.2
Wente, S.R.3
-
73
-
-
0042238022
-
RanGTP mediates nuclear pore complex assembly
-
Walther TC, Askjaer P, Gentzel M, Habermann A, Griffiths G, Wilm M, Mattaj IW, Hetzer M. RanGTP mediates nuclear pore complex assembly. Nature 2003; 424: 689–694.
-
(2003)
Nature
, vol.424
, pp. 689-694
-
-
Walther, T.C.1
Askjaer, P.2
Gentzel, M.3
Habermann, A.4
Griffiths, G.5
Wilm, M.6
Mattaj, I.W.7
Hetzer, M.8
-
74
-
-
1842835691
-
Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly
-
Zhang C, Goldberg MW, Moore WJ, Allen TD, Clarke PR. Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly. Eur J Cell Biol 2002; 81: 623–633.
-
(2002)
Eur J Cell Biol
, vol.81
, pp. 623-633
-
-
Zhang, C.1
Goldberg, M.W.2
Moore, W.J.3
Allen, T.D.4
Clarke, P.R.5
-
75
-
-
0036911347
-
Ran GTPase cycle and importins α and β are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos
-
Askjaer P, Galy V, Hannak E, Mattaj IW. Ran GTPase cycle and importins α and β are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos. Mol Biol Cell 2002; 13: 4355–4370.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 4355-4370
-
-
Askjaer, P.1
Galy, V.2
Hannak, E.3
Mattaj, I.W.4
-
76
-
-
0036006303
-
The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo
-
Bamba C, Bobinnec Y, Fukuda M, Nishida E. The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo. Curr Biol 2002; 12: 503–507.
-
(2002)
Curr Biol
, vol.12
, pp. 503-507
-
-
Bamba, C.1
Bobinnec, Y.2
Fukuda, M.3
Nishida, E.4
-
77
-
-
0037089085
-
The importin-β P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope
-
Timinszky G, Tirián L, Nagy FT, Töth G, Perczel A, Kiss-Lászlá Z, Boros I, Clarke PR, Szabad J. The importin-β P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope. J Cell Sci 2002; 115: 1675–1687.
-
(2002)
J Cell Sci
, vol.115
, pp. 1675-1687
-
-
Timinszky, G.1
Tirián, L.2
Nagy, F.T.3
Töth, G.4
Perczel, A.5
Kiss-Lászlá, Z.6
Boros, I.7
Clarke, P.R.8
Szabad, J.9
-
78
-
-
0037417808
-
Depletion of a single nucleoporin, Nup 107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex
-
Boehmer T, Enninga J, Dales S, Blobel G, Zhong H. Depletion of a single nucleoporin, Nup 107, prevents the assembly of a subset of nucleoporins into the nuclear pore complex. Proc Natl Acad Sci USA 2003; 100: 981–985.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 981-985
-
-
Boehmer, T.1
Enninga, J.2
Dales, S.3
Blobel, G.4
Zhong, H.5
-
79
-
-
0242668887
-
The conserved Nup 107–160 complex is critical for nuclear pore complex assembly
-
Walther TC, Alves A, Pickersgill H, Loïodice I, Hetzer M, Galy V, Hülsmann BB, Kouml;cher T, Wilm M, Allen T, Mattaj IW, Doye V. The conserved Nup 107–160 complex is critical for nuclear pore complex assembly. Cell 2003; 113: 195–206.
-
(2003)
Cell
, vol.113
, pp. 195-206
-
-
Walther, T.C.1
Alves, A.2
Pickersgill, H.3
Loïodice, I.4
Hetzer, M.5
Galy, V.6
Hülsmann, B.B.7
Kouml8
cher, T.9
Wilm, M.10
Allen, T.11
Mattaj, I.W.12
Doye, V.13
-
80
-
-
0037547118
-
Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores
-
Harel A, Orjalo AV, Vincent T, Lachish-Zalait A, Vasu S, Shah S, Zimmerman E, Elbaum M, Forbes DJ. Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores. Mol Cell 2003; 11: 853–864.
-
(2003)
Mol Cell
, vol.11
, pp. 853-864
-
-
Harel, A.1
Orjalo, A.V.2
Vincent, T.3
Lachish-Zalait, A.4
Vasu, S.5
Shah, S.6
Zimmerman, E.7
Elbaum, M.8
Forbes, D.J.9
-
81
-
-
33645962474
-
Nuclear pores form de novo from both sides of the nuclear envelope
-
D'Angelo MA, Anderson DJ, Richard E, Hetzer MW. Nuclear pores form de novo from both sides of the nuclear envelope. Science 2006; 312: 440–443.
-
(2006)
Science
, vol.312
, pp. 440-443
-
-
D'Angelo, M.A.1
Anderson, D.J.2
Richard, E.3
Hetzer, M.W.4
-
82
-
-
33747827759
-
MEL-28, a novel nuclear-envelope and kinetochore protein essential for zygotic nuclear-envelope assembly in C. elegans
-
Galy V, Askjaer P, Franz C, López-Iglesias C, Mattaj IW. MEL-28, a novel nuclear-envelope and kinetochore protein essential for zygotic nuclear-envelope assembly in C. elegans. Curr Biol 2006; 16: 1748–1756.
-
(2006)
Curr Biol
, vol.16
, pp. 1748-1756
-
-
Galy, V.1
Askjaer, P.2
Franz, C.3
López-Iglesias, C.4
Mattaj, I.W.5
-
83
-
-
33747821629
-
MEL-28 is downstream of the Ran cycle and is required for nuclear-envelope function and chromatin maintenance
-
Fernandez AG, Piano F. MEL-28 is downstream of the Ran cycle and is required for nuclear-envelope function and chromatin maintenance. Curr Biol 2006; 16: 1757–1763.
-
(2006)
Curr Biol
, vol.16
, pp. 1757-1763
-
-
Fernandez, A.G.1
Piano, F.2
-
84
-
-
33845227470
-
ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division
-
Rasala BA, Orjalo AV, Shen Z, Briggs S, Forbes DJ. ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division. Proc Natl Acad Sci USA 2006; 103: 17801–17806.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17801-17806
-
-
Rasala, B.A.1
Orjalo, A.V.2
Shen, Z.3
Briggs, S.4
Forbes, D.J.5
-
85
-
-
33947270331
-
MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly
-
Franz C, Walczak R, Yavuz S, Santarella R, Gentzel M, Askjaer P, Galy V, Hetzer M, Mattaj IW, Antonin W. MEL-28/ELYS is required for the recruitment of nucleoporins to chromatin and postmitotic nuclear pore complex assembly. EMBO Rep 2007; 8: 165–172.
-
(2007)
EMBO Rep
, vol.8
, pp. 165-172
-
-
Franz, C.1
Walczak, R.2
Yavuz, S.3
Santarella, R.4
Gentzel, M.5
Askjaer, P.6
Galy, V.7
Hetzer, M.8
Mattaj, I.W.9
Antonin, W.10
-
86
-
-
0345374574
-
Importin β negatively regulates nuclear membrane fusion and nuclear pore complex assembly
-
Harel A, Chan RC, Lachish-Zalait A, Zimmerman E, Elbaum M, Forbes DJ. Importin β negatively regulates nuclear membrane fusion and nuclear pore complex assembly. Mol Biol Cell 2003; 14: 4387–4396.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 4387-4396
-
-
Harel, A.1
Chan, R.C.2
Lachish-Zalait, A.3
Zimmerman, E.4
Elbaum, M.5
Forbes, D.J.6
-
87
-
-
34848827190
-
ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing
-
Gillespie PJ, Khoudoli GA, Stewart G, Swedlow JR, Blow JJ. ELYS/MEL-28 chromatin association coordinates nuclear pore complex assembly and replication licensing. Curr Biol 2007; 17L: 1657–1662.
-
(2007)
Curr Biol
, vol.17L
, pp. 1657-1662
-
-
Gillespie, P.J.1
Khoudoli, G.A.2
Stewart, G.3
Swedlow, J.R.4
Blow, J.J.5
-
88
-
-
77953724768
-
Cell cycle-dependent differences in nuclear pore complex assembly in metazoa
-
Doucet CM, Talamas JA, Hetzer MW. Cell cycle-dependent differences in nuclear pore complex assembly in metazoa. Cell 2010; 141: 1030–1041.
-
(2010)
Cell
, vol.141
, pp. 1030-1041
-
-
Doucet, C.M.1
Talamas, J.A.2
Hetzer, M.W.3
-
89
-
-
77955270200
-
NLS-mediated NPC functions of the nucleoporin Pom121
-
Yavuz S, Santarella-Mellwig R, Koch B, Jaedicke A, Mattaj IW, Antonin W. NLS-mediated NPC functions of the nucleoporin Pom121. FEBS Lett 2010; 584: 3292–3298.
-
(2010)
FEBS Lett
, vol.584
, pp. 3292-3298
-
-
Yavuz, S.1
Santarella-Mellwig, R.2
Koch, B.3
Jaedicke, A.4
Mattaj, I.W.5
Antonin, W.6
-
90
-
-
77957743829
-
Live imaging of single nuclear pores reveals unique assembly kinetics and mechanism in interphase
-
Dultz E, Ellenberg J. Live imaging of single nuclear pores reveals unique assembly kinetics and mechanism in interphase. J Cell Biol 2010; 191: 15–22.
-
(2010)
J Cell Biol
, vol.191
, pp. 15-22
-
-
Dultz, E.1
Ellenberg, J.2
-
91
-
-
79953296849
-
Localization of Pom121 to the inner nuclear membrane is required for an early step of interphase nuclear pore complex assembly
-
Funakoshi T, Clever M, Watanabe A, Imamoto N. Localization of Pom121 to the inner nuclear membrane is required for an early step of interphase nuclear pore complex assembly. Mol Biol Cell 2011; 22: 1058–1069.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 1058-1069
-
-
Funakoshi, T.1
Clever, M.2
Watanabe, A.3
Imamoto, N.4
-
92
-
-
79960233453
-
POM121 and Sun1 play a role in early steps of interphase NPC assembly
-
Talamas JA, Hetzer MW. POM121 and Sun1 play a role in early steps of interphase NPC assembly. J Cell Biol 2011; 194: 27–37.
-
(2011)
J Cell Biol
, vol.194
, pp. 27-37
-
-
Talamas, J.A.1
Hetzer, M.W.2
-
93
-
-
78249270438
-
Reduced Ran expression in Ran(+ /-) fibroblasts increases cytokine-stimulated nuclear abundance of the AP-1 subunits c-Fos and c-Jun
-
Pham DN, Luo H, Wu J. Reduced Ran expression in Ran(+ /-) fibroblasts increases cytokine-stimulated nuclear abundance of the AP-1 subunits c-Fos and c-Jun. FEBS Lett 2010; 584: 4263–4266.
-
(2010)
FEBS Lett
, vol.584
, pp. 4263-4266
-
-
Pham, D.N.1
Luo, H.2
Wu, J.3
-
94
-
-
77949320905
-
Ran overexpression leads to diminished T cell responses and selectively modulates nuclear levels of c-Jun and c-Fos
-
Qiao X, Pham DN, Luo H, Wu J. Ran overexpression leads to diminished T cell responses and selectively modulates nuclear levels of c-Jun and c-Fos. J Biol Chem 2010; 285: 5488–5496.
-
(2010)
J Biol Chem
, vol.285
, pp. 5488-5496
-
-
Qiao, X.1
Pham, D.N.2
Luo, H.3
Wu, J.4
-
95
-
-
77954244487
-
Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β 2 and RanGTP
-
Dishinger JF, Kee HL, Jenkins PM, Fan S, Hurd TW, Hammond JW, Truong YN, Margolis B, Martens JR, Verhey KJ. Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β 2 and RanGTP. Nat Cell Biol 2010; 12: 703–710.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 703-710
-
-
Dishinger, J.F.1
Kee, H.L.2
Jenkins, P.M.3
Fan, S.4
Hurd, T.W.5
Hammond, J.W.6
Truong, Y.N.7
Margolis, B.8
Martens, J.R.9
Verhey, K.J.10
-
96
-
-
47749146105
-
Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve
-
Yudin D, Hanz S, Yoo S, Iavnilovitch E, Willis D, Gradus T, Vuppalanchi D, Segal-Ruder Y, Ben-Yaakov K, Hieda M, Yoneda Y, Twiss JL, Fainzilber M. Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve. Neuron 2008; 59: 241–252.
-
(2008)
Neuron
, vol.59
, pp. 241-252
-
-
Yudin, D.1
Hanz, S.2
Yoo, S.3
Iavnilovitch, E.4
Willis, D.5
Gradus, T.6
Vuppalanchi, D.7
Segal-Ruder, Y.8
Ben-Yaakov, K.9
Hieda, M.10
Yoneda, Y.11
Twiss, J.L.12
Fainzilber, M.13
-
97
-
-
9144273965
-
Axoplasmic importins enable retrograde injury signaling in lesioned nerve
-
Hanz S, Perlson E, Willis D, Zheng JQ, Massarwa R, Huerta JJ, Koltzenburg M, Kohler M, van-Minnen J, Twiss JL, Fainzilber M. Axoplasmic importins enable retrograde injury signaling in lesioned nerve. Neuron 2003; 40: 1095–1114.
-
(2003)
Neuron
, vol.40
, pp. 1095-1114
-
-
Hanz, S.1
Perlson, E.2
Willis, D.3
Zheng, J.Q.4
Massarwa, R.5
Huerta, J.J.6
Koltzenburg, M.7
Kohler, M.8
van-Minnen, J.9
Twiss, J.L.10
Fainzilber, M.11
-
98
-
-
79952314789
-
Mice lacking Ran binding protein 1 are viable and show male infertility
-
Nagai M, Moriyama T, Mehmood R, Tokuhiro K, Ikawa M, Okabe M, Tanaka H, Yoneda Y. Mice lacking Ran binding protein 1 are viable and show male infertility. FEBS Lett 2011; 585: 791–796.
-
(2011)
FEBS Lett
, vol.585
, pp. 791-796
-
-
Nagai, M.1
Moriyama, T.2
Mehmood, R.3
Tokuhiro, K.4
Ikawa, M.5
Okabe, M.6
Tanaka, H.7
Yoneda, Y.8
-
99
-
-
0028055187
-
A murine homolog of the yeast RNA1 gene is required for postimplantation development
-
DeGregori J, Russ A, von Melchner H, Rayburn H, Priyaranjan P, Jenkins NA, Copeland NG, Ruley HE. A murine homolog of the yeast RNA1 gene is required for postimplantation development. Genes Dev 1994; 8: 265–276.
-
(1994)
Genes Dev
, vol.8
, pp. 265-276
-
-
DeGregori, J.1
Russ, A.2
von Melchner, H.3
Rayburn, H.4
Priyaranjan, P.5
Jenkins, N.A.6
Copeland, N.G.7
Ruley, H.E.8
-
100
-
-
33750429598
-
RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism
-
Aslanukov A, Bhowmick R, Guruju M, Oswald J, Raz D, Bush RA, Sieving PA, Lu X, Bock CB, Ferreira PA. RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. PLoS Genet 2006; 2: e177.
-
(2006)
PLoS Genet
, vol.2
, pp. e177
-
-
Aslanukov, A.1
Bhowmick, R.2
Guruju, M.3
Oswald, J.4
Raz, D.5
Bush, R.A.6
Sieving, P.A.7
Lu, X.8
Bock, C.B.9
Ferreira, P.A.10
-
101
-
-
41149146735
-
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIα
-
Dawlaty MM, Malureanu L, Jeganathan KB, Kao E, Sustmann C, Tahk S, Shuai K, Grosschedl R, van Deursen JM. Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIα. Cell 2008; 133: 103–115.
-
(2008)
Cell
, vol.133
, pp. 103-115
-
-
Dawlaty, M.M.1
Malureanu, L.2
Jeganathan, K.B.3
Kao, E.4
Sustmann, C.5
Tahk, S.6
Shuai, K.7
Grosschedl, R.8
van Deursen, J.M.9
-
102
-
-
30944452120
-
Impaired expression of importin/karyopherin β 1 leads to post-implantation lethality
-
Miura K, Yoshinobu K, Imaizumi T, Haruna K, Miyamoto Y, Yoneda Y, Nakagata N, Araki M, Miyakawa T, Yamamura K, Araki K. Impaired expression of importin/karyopherin β 1 leads to post-implantation lethality. Biochem Biophys Res Commun 2006; 341: 132–138.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 132-138
-
-
Miura, K.1
Yoshinobu, K.2
Imaizumi, T.3
Haruna, K.4
Miyamoto, Y.5
Yoneda, Y.6
Nakagata, N.7
Araki, M.8
Miyakawa, T.9
Yamamura, K.10
Araki, K.11
-
103
-
-
0037162398
-
The Ran GTPase: theme and variations
-
Dasso M. The Ran GTPase: theme and variations. Curr Biol 2002; 12: R502–8.
-
(2002)
Curr Biol
, vol.12
, pp. R502-8
-
-
Dasso, M.1
-
104
-
-
79751494399
-
Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis
-
Asally M, Yasuda Y, Oka M, Otsuka S, Yoshimura SH, Takeyasu K, Yoneda Y. Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis. FEBS J 2011; 278: 610–621.
-
(2011)
FEBS J
, vol.278
, pp. 610-621
-
-
Asally, M.1
Yasuda, Y.2
Oka, M.3
Otsuka, S.4
Yoshimura, S.H.5
Takeyasu, K.6
Yoneda, Y.7
-
105
-
-
38949159953
-
Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport
-
Yoon SO, Shin S, Liu Y, Ballif BA, Woo MS, Gygi SP, Blenis J. Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transport. Mol Cell 2008; 29: 362–375.
-
(2008)
Mol Cell
, vol.29
, pp. 362-375
-
-
Yoon, S.O.1
Shin, S.2
Liu, Y.3
Ballif, B.A.4
Woo, M.S.5
Gygi, S.P.6
Blenis, J.7
-
106
-
-
61749096309
-
Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-β signaling
-
Dai F, Lin X, Chang C, Feng XH. Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-β signaling. Dev Cell 2009; 16: 345–357.
-
(2009)
Dev Cell
, vol.16
, pp. 345-357
-
-
Dai, F.1
Lin, X.2
Chang, C.3
Feng, X.H.4
-
107
-
-
34547956843
-
hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes
-
Tanaka T, Ohkubo S, Tatsuno I, Prives C. hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes. Cell 2007; 130: 638–650.
-
(2007)
Cell
, vol.130
, pp. 638-650
-
-
Tanaka, T.1
Ohkubo, S.2
Tatsuno, I.3
Prives, C.4
-
108
-
-
0034663939
-
Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes
-
Lipowsky G, Bischoff FR, Schwarzmaier P, Kraft R, Kostka S, Hartmann E, Kutay U, Görlich D. Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes. EMBO J 2000; 19: 4362–4371.
-
(2000)
EMBO J
, vol.19
, pp. 4362-4371
-
-
Lipowsky, G.1
Bischoff, F.R.2
Schwarzmaier, P.3
Kraft, R.4
Kostka, S.5
Hartmann, E.6
Kutay, U.7
Görlich, D.8
-
109
-
-
56349121125
-
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer
-
Zender L, Xue W, Zuber J, Semighini CP, Krasnitz A, Ma B, Zender P, Kubicka S, Luk JM, Schirmacher P, McCombie WR, Wigler M, Hicks J, Hannon GJ, Powers S, Lowe SW. An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer. Cell 2008; 135: 852–864.
-
(2008)
Cell
, vol.135
, pp. 852-864
-
-
Zender, L.1
Xue, W.2
Zuber, J.3
Semighini, C.P.4
Krasnitz, A.5
Ma, B.6
Zender, P.7
Kubicka, S.8
Luk, J.M.9
Schirmacher, P.10
McCombie, W.R.11
Wigler, M.12
Hicks, J.13
Hannon, G.J.14
Powers, S.15
Lowe, S.W.16
-
110
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003; 17: 3011–3016.
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
111
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Güttinger S, Calado A, Dahlberg JE, Kutay U. Nuclear export of microRNA precursors. Science 2004; 303: 95–98.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Güttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
112
-
-
1642499415
-
Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
-
Bohnsack MT, Czaplinski K, Görlich D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 2004; 10: 185–191.
-
(2004)
RNA
, vol.10
, pp. 185-191
-
-
Bohnsack, M.T.1
Czaplinski, K.2
Görlich, D.3
-
113
-
-
77957940475
-
A genetic defect in exportin 5 traps precursor microRNAs in the nucleus of cancer cells
-
Melo SA, Moutinho C, Ropero S, Calin GA, Rossi S, Spizzo R, Fernandez AF, Davalos V, Villanueva A, Montoya G, Yamamoto H, Schwartz S Jr, Esteller M. A genetic defect in exportin 5 traps precursor microRNAs in the nucleus of cancer cells. Cancer Cell 2010; 18: 303–315.
-
(2010)
Cancer Cell
, vol.18
, pp. 303-315
-
-
Melo, S.A.1
Moutinho, C.2
Ropero, S.3
Calin, G.A.4
Rossi, S.5
Spizzo, R.6
Fernandez, A.F.7
Davalos, V.8
Villanueva, A.9
Montoya, G.10
Yamamoto, H.11
Schwartz, S.12
Esteller, M.13
-
114
-
-
46649086170
-
RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules
-
Schulze H, Dose M, Korpal M, Meyer I, Italiano JE Jr, Shivdasani RA. RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules. J Biol Chem 2008; 283: 14109–14119.
-
(2008)
J Biol Chem
, vol.283
, pp. 14109-14119
-
-
Schulze, H.1
Dose, M.2
Korpal, M.3
Meyer, I.4
Italiano, J.E.5
Shivdasani, R.A.6
-
115
-
-
0034627771
-
Hydrogen peroxide inhibition of nuclear protein import is mediated by the mitogenactivated protein kinase, ERK2
-
Czubryt MP, Austria JA, Pierce GN. Hydrogen peroxide inhibition of nuclear protein import is mediated by the mitogenactivated protein kinase, ERK2. J Cell Biol 2000; 148: 7–16.
-
(2000)
J Cell Biol
, vol.148
, pp. 7-16
-
-
Czubryt, M.P.1
Austria, J.A.2
Pierce, G.N.3
-
116
-
-
0033729420
-
Stress-mediated inhibition of the classical nuclear protein import pathway and nuclear accumulation of the small GTPase Gsp1p
-
Stochaj U, Rassadi R, Chiu J. Stress-mediated inhibition of the classical nuclear protein import pathway and nuclear accumulation of the small GTPase Gsp1p. FASEB J 2000; 14: 2130–2132.
-
(2000)
FASEB J
, vol.14
, pp. 2130-2132
-
-
Stochaj, U.1
Rassadi, R.2
Chiu, J.3
-
117
-
-
2942653489
-
Cellular stresses induce the nuclear accumulation of importin α and cause a conventional nuclear import block
-
Miyamoto Y, Saiwaki T, Yamashita J, Yasuda Y, Kotera I, Shibata S, Shigeta M, Hiraoka Y, Haraguchi T, Yoneda Y. Cellular stresses induce the nuclear accumulation of importin α and cause a conventional nuclear import block. J Cell Biol 2004; 165: 617–623.
-
(2004)
J Cell Biol
, vol.165
, pp. 617-623
-
-
Miyamoto, Y.1
Saiwaki, T.2
Yamashita, J.3
Yasuda, Y.4
Kotera, I.5
Shibata, S.6
Shigeta, M.7
Hiraoka, Y.8
Haraguchi, T.9
Yoneda, Y.10
-
118
-
-
4344582296
-
Multiple mechanisms promote the classical nuclear import upon exposure to severe oxidative stress
-
Kodiha M, Chu A, Matusiewicz N, Stochaj U. Multiple mechanisms promote the classical nuclear import upon exposure to severe oxidative stress. Cell Death Differ 2004; 11: 862–874.
-
(2004)
Cell Death Differ
, vol.11
, pp. 862-874
-
-
Kodiha, M.1
Chu, A.2
Matusiewicz, N.3
Stochaj, U.4
-
119
-
-
29144517768
-
Mechanism of the stress-induced collapse of the Ran distribution
-
Yasuda Y, Miyamoto Y, Saiwaki T, Yoneda Y. Mechanism of the stress-induced collapse of the Ran distribution. Exp Cell Res 2006; 312: 512–520.
-
(2006)
Exp Cell Res
, vol.312
, pp. 512-520
-
-
Yasuda, Y.1
Miyamoto, Y.2
Saiwaki, T.3
Yoneda, Y.4
-
120
-
-
84855348247
-
Nuclear retention of importin α coordinates cell fate through changes in gene expression
-
Yasuda Y, Miyamoto Y, Yamashiro T, Asally M, Masui A, Wong C, Loveland KL, Yoneda Y. Nuclear retention of importin α coordinates cell fate through changes in gene expression. EMBO J 2012; 31: 83–94.
-
(2012)
EMBO J
, vol.31
, pp. 83-94
-
-
Yasuda, Y.1
Miyamoto, Y.2
Yamashiro, T.3
Asally, M.4
Masui, A.5
Wong, C.6
Loveland, K.L.7
Yoneda, Y.8
-
121
-
-
33845888271
-
Triggering neural differentiation of ES cells by subtype switching of importin-α
-
Yasuhara N, Shibazaki N, Tanaka S, Nagai M, Kamikawa Y, Oe S, Asally M, Kamachi Y, Kondoh H, Yoneda Y. Triggering neural differentiation of ES cells by subtype switching of importin-α. Nat Cell Biol 2007; 9: 72–79.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 72-79
-
-
Yasuhara, N.1
Shibazaki, N.2
Tanaka, S.3
Nagai, M.4
Kamikawa, Y.5
Oe, S.6
Asally, M.7
Kamachi, Y.8
Kondoh, H.9
Yoneda, Y.10
-
122
-
-
80355148459
-
Distinct effects of importin α2 and α4 on Oct3/4 localization and expression in mouse embryonic stem cells
-
Young JC, Major AT, Miyamoto Y, Loveland KL, Jans DA. Distinct effects of importin α2 and α4 on Oct3/4 localization and expression in mouse embryonic stem cells. FASEB J 2011; 25: 3958–3965.
-
(2011)
FASEB J
, vol.25
, pp. 3958-3965
-
-
Young, J.C.1
Major, A.T.2
Miyamoto, Y.3
Loveland, K.L.4
Jans, D.A.5
-
123
-
-
67649452381
-
The role of the nuclear transport system in cell differentiation
-
Yasuhara N, Oka M, Yoneda Y. The role of the nuclear transport system in cell differentiation. Semin Cell Dev Biol 2009; 20: 590–599.
-
(2009)
Semin Cell Dev Biol
, vol.20
, pp. 590-599
-
-
Yasuhara, N.1
Oka, M.2
Yoneda, Y.3
-
124
-
-
67649452378
-
Nucleocytoplasmic transport as a driver of mammalian game-togenesis
-
Itman C, Miyamoto Y, Young J, Jans DA, Loveland KL. Nucleocytoplasmic transport as a driver of mammalian game-togenesis. Semin Cell Dev Biol 2009; 20: 607–619.
-
(2009)
Semin Cell Dev Biol
, vol.20
, pp. 607-619
-
-
Itman, C.1
Miyamoto, Y.2
Young, J.3
Jans, D.A.4
Loveland, K.L.5
-
125
-
-
42949167771
-
The GTPase Ran: regulation of cell life and potential roles in cell transformation
-
Rensen WM, Mangiacasale R, Ciciarello M, Lavia P. The GTPase Ran: regulation of cell life and potential roles in cell transformation. Front Biosci 2008; 13: 4097–4121.
-
(2008)
Front Biosci
, vol.13
, pp. 4097-4121
-
-
Rensen, W.M.1
Mangiacasale, R.2
Ciciarello, M.3
Lavia, P.4
-
126
-
-
33745451273
-
Tissue array analysis of expression microarray candidates identifies markers associated with tumor grade and outcome in serous epithelial ovarian cancer
-
Ouellet V, Guyot MC, Le Page C, Filali-Mouhim A, Lussier C, Tonin PN, Provencher DM, Mes-Masson AM. Tissue array analysis of expression microarray candidates identifies markers associated with tumor grade and outcome in serous epithelial ovarian cancer. Int J Cancer 2006; 119: 599–607.
-
(2006)
Int J Cancer
, vol.119
, pp. 599-607
-
-
Ouellet, V.1
Guyot, M.C.2
Le Page, C.3
Filali-Mouhim, A.4
Lussier, C.5
Tonin, P.N.6
Provencher, D.M.7
Mes-Masson, A.M.8
-
127
-
-
42149128181
-
High expression of Ran GTPase is associated with local invasion and metastasis of human clear cell renal cell carcinoma
-
Abe H, Kamai T, Shirataki H, Oyama T, Arai K, Yoshida K. High expression of Ran GTPase is associated with local invasion and metastasis of human clear cell renal cell carcinoma. Int J Cancer 2008; 122: 2391–2397.
-
(2008)
Int J Cancer
, vol.122
, pp. 2391-2397
-
-
Abe, H.1
Kamai, T.2
Shirataki, H.3
Oyama, T.4
Arai, K.5
Yoshida, K.6
-
128
-
-
57349130560
-
RAN GTPase is an effector of the invasive/metastatic phenotype induced by osteopontin
-
Kurisetty VV, Johnston PG, Johnston N, Erwin P, Crowe P, Fernig DG, Campbell FC, Anderson IP, Rudland PS, El-Tanani MK. RAN GTPase is an effector of the invasive/metastatic phenotype induced by osteopontin. Oncogene 2008; 27: 7139–7149.
-
(2008)
Oncogene
, vol.27
, pp. 7139-7149
-
-
Kurisetty, V.V.1
Johnston, P.G.2
Johnston, N.3
Erwin, P.4
Crowe, P.5
Fernig, D.G.6
Campbell, F.C.7
Anderson, I.P.8
Rudland, P.S.9
El-Tanani, M.K.10
-
129
-
-
77949326178
-
Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation
-
Ly TK, Wang J, Pereira R, Rojas KS, Peng X, Feng Q, Cerione RA, Wilson KF. Activation of the Ran GTPase is subject to growth factor regulation and can give rise to cellular transformation. J Biol Chem 2010; 285: 5815–5826.
-
(2010)
J Biol Chem
, vol.285
, pp. 5815-5826
-
-
Ly, T.K.1
Wang, J.2
Pereira, R.3
Rojas, K.S.4
Peng, X.5
Feng, Q.6
Cerione, R.A.7
Wilson, K.F.8
-
130
-
-
34249285532
-
Identification of Ras-related nuclear protein, targeting protein for Xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen
-
Morgan-Lappe SE, Tucker LA, Huang X, Zhang Q, Sarthy AV, Zakula D, Vernetti L, Schurdak M, Wang J, Fesik SW. Identification of Ras-related nuclear protein, targeting protein for Xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen. Cancer Res 2007; 67: 4390–4398.
-
(2007)
Cancer Res
, vol.67
, pp. 4390-4398
-
-
Morgan-Lappe, S.E.1
Tucker, L.A.2
Huang, X.3
Zhang, Q.4
Sarthy, A.V.5
Zakula, D.6
Vernetti, L.7
Schurdak, M.8
Wang, J.9
Fesik, S.W.10
-
131
-
-
50249148427
-
A survivin-ran complex regulates spindle formation in tumor cells
-
Xia F, Canovas PM, Guadagno TM, Altieri DC. A survivin-ran complex regulates spindle formation in tumor cells. Mol Cell Biol 2008; 28: 5299–5311.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5299-5311
-
-
Xia, F.1
Canovas, P.M.2
Guadagno, T.M.3
Altieri, D.C.4
-
132
-
-
34548232343
-
Coordination of chromosome alignment and mitotic progression by the chromosome-based Ran signal
-
Li HY, Ng WP, Wong CH, Iglesias PA, Zheng Y. Coordination of chromosome alignment and mitotic progression by the chromosome-based Ran signal. Cell Cycle 2007; 6: 1886–1895.
-
(2007)
Cell Cycle
, vol.6
, pp. 1886-1895
-
-
Li, H.Y.1
Ng, W.P.2
Wong, C.H.3
Iglesias, P.A.4
Zheng, Y.5
-
133
-
-
36549085093
-
RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells
-
Tedeschi A, Ciciarello M, Mangiacasale R, Roscioli E, Rensen WM, Lavia P. RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells. J Cell Sci 2007; 120: 3748–3761.
-
(2007)
J Cell Sci
, vol.120
, pp. 3748-3761
-
-
Tedeschi, A.1
Ciciarello, M.2
Mangiacasale, R.3
Roscioli, E.4
Rensen, W.M.5
Lavia, P.6
-
134
-
-
65049085143
-
RanBP1 downregulation sensitizes cancer cells to taxol in a caspase-3-dependent manner
-
Rensen WM, Roscioli E, Tedeschi A, Mangiacasale R, Ciciarello M, Di Gioia SA, Lavia P. RanBP1 downregulation sensitizes cancer cells to taxol in a caspase-3-dependent manner. Oncogene 2009; 28: 1748–1758.
-
(2009)
Oncogene
, vol.28
, pp. 1748-1758
-
-
Rensen, W.M.1
Roscioli, E.2
Tedeschi, A.3
Mangiacasale, R.4
Ciciarello, M.5
Di Gioia, S.A.6
Lavia, P.7
-
135
-
-
0026694826
-
Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion
-
Moll UM, Riou G, Levine AJ. Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci USA 1992; 89: 7262–7265.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7262-7265
-
-
Moll, U.M.1
Riou, G.2
Levine, A.J.3
-
136
-
-
0029049828
-
Wild-type p53 protein undergoescytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors
-
Moll UM, LaQuaglia M, Bénard J, Riou G. Wild-type p53 protein undergoescytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors. Proc Natl Acad Sci USA 1995; 92: 4407–4411.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4407-4411
-
-
Moll, U.M.1
LaQuaglia, M.2
Bénard, J.3
Riou, G.4
-
137
-
-
0036799377
-
PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization
-
Shin I, Yakes FM, Rojo F, Shin NY, Bakin AV, Baselga J, Arteaga CL. PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization. Nat Med 2002; 8: 1145–1152.
-
(2002)
Nat Med
, vol.8
, pp. 1145-1152
-
-
Shin, I.1
Yakes, F.M.2
Rojo, F.3
Shin, N.Y.4
Bakin, A.V.5
Baselga, J.6
Arteaga, C.L.7
-
138
-
-
18644376449
-
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest
-
Liang J, Zubovitz J, Petrocelli T, Kotchetkov R, Connor MK, Han K, Lee JH, Ciarallo S, Catzavelos C, Beniston R, Franssen E, Slingerland JM. PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest. Nat Med 2002; 8: 1153–1160.
-
(2002)
Nat Med
, vol.8
, pp. 1153-1160
-
-
Liang, J.1
Zubovitz, J.2
Petrocelli, T.3
Kotchetkov, R.4
Connor, M.K.5
Han, K.6
Lee, J.H.7
Ciarallo, S.8
Catzavelos, C.9
Beniston, R.10
Franssen, E.11
Slingerland, J.M.12
-
139
-
-
18644370396
-
Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer
-
Viglietto G, Motti ML, Bruni P, Melillo RM, D'Alessio A, Califano D, Vinci F, Chiappetta G, Tsichlis P, Bellacosa A, Fusco A, Santoro M. Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer. Nat Med 2002; 8: 1136–1144.
-
(2002)
Nat Med
, vol.8
, pp. 1136-1144
-
-
Viglietto, G.1
Motti, M.L.2
Bruni, P.3
Melillo, R.M.4
D'Alessio, A.5
Califano, D.6
Vinci, F.7
Chiappetta, G.8
Tsichlis, P.9
Bellacosa, A.10
Fusco, A.11
Santoro, M.12
-
140
-
-
3142512358
-
14–3–3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)
-
Sekimoto T, Fukumoto M, Yoneda Y. 14–3–3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1). EMBO J 2004; 23: 1934–1942.
-
(2004)
EMBO J
, vol.23
, pp. 1934-1942
-
-
Sekimoto, T.1
Fukumoto, M.2
Yoneda, Y.3
-
141
-
-
67650754585
-
Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function
-
Lobo GP, Waite KA, Planchon SM, Romigh T, Nassif NT, Eng C. Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function. Hum Mol Genet 2009; 18: 2851–2862.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 2851-2862
-
-
Lobo, G.P.1
Waite, K.A.2
Planchon, S.M.3
Romigh, T.4
Nassif, N.T.5
Eng, C.6
-
142
-
-
0037440429
-
Regulation of tumor suppressors by nuclear-cytoplasmic shuttling
-
Fabbro M, Henderson BR. Regulation of tumor suppressors by nuclear-cytoplasmic shuttling. Exp Cell Res 2003; 282: 59–69.
-
(2003)
Exp Cell Res
, vol.282
, pp. 59-69
-
-
Fabbro, M.1
Henderson, B.R.2
-
143
-
-
66149101014
-
Ran on tracks. cytoplasmic roles for a nuclear regulator
-
Yudin D, Fainzilber Y. Ran on tracks. cytoplasmic roles for a nuclear regulator. J Cell Sci 2009; 122: 587–593.
-
(2009)
J Cell Sci
, vol.122
, pp. 587-593
-
-
Yudin, D.1
Fainzilber, Y.2
|