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Volumn 116, Issue 23, 2003, Pages 4791-4798

Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation

Author keywords

Microtubules; Mitosis; Spindle assembly

Indexed keywords

AURORA A KINASE; CELL NUCLEUS RECEPTOR; DNA; GUANOSINE TRIPHOSPHATASE; KARYOPHERIN BETA; KINESIN; PHOSPHOTRANSFERASE; PROTEIN KID; PROTEIN TPX2; RAN PROTEIN; RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 0348013019     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00798     Document Type: Article
Times cited : (101)

References (39)
  • 1
    • 0030663597 scopus 로고    scopus 로고
    • XMAP310: A Xenopus rescue-promoting factor localized to the mitotic spindle
    • Andersen, S. S. L. and Karsenti, E. (1997). XMAP310: A Xenopus rescue-promoting factor localized to the mitotic spindle. J. Cell Biol. 139, 975-983.
    • (1997) J. Cell Biol. , vol.139 , pp. 975-983
    • Andersen, S.S.L.1    Karsenti, E.2
  • 2
    • 0034682704 scopus 로고    scopus 로고
    • Xkid, a chromokinesin required for chromosome alignment on the metaphase plate
    • Antonio, C., Ferby, I., Wilhelm, H., Jones, M., Karsenti, E., Nebrada, A. R. and Vernos, I. (2000). Xkid, a chromokinesin required for chromosome alignment on the metaphase plate. Cell 102, 425-435.
    • (2000) Cell , vol.102 , pp. 425-435
    • Antonio, C.1    Ferby, I.2    Wilhelm, H.3    Jones, M.4    Karsenti, E.5    Nebrada, A.R.6    Vernos, I.7
  • 3
    • 0033536178 scopus 로고    scopus 로고
    • Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation
    • Carazo-Salas, R. E., Guarguaglini, G., Gruss, O. J., Segref, A., Karsenti, E. and Mattaj, I. W. (1999). Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 400, 178-181.
    • (1999) Nature , vol.400 , pp. 178-181
    • Carazo-Salas, R.E.1    Guarguaglini, G.2    Gruss, O.J.3    Segref, A.4    Karsenti, E.5    Mattaj, I.W.6
  • 4
    • 0035090344 scopus 로고    scopus 로고
    • Ran-GTP coordinates regulation of microtubule nucleation and dnamics during mitotic-spindle assembly
    • Carazo-Salas, R. E., Gross, O. J., Mattaj, I. W. and Karsenti, E. (2001). Ran-GTP coordinates regulation of microtubule nucleation and dnamics during mitotic-spindle assembly. Nat. Cell Biol. 3, 228-234.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 228-234
    • Carazo-Salas, R.E.1    Gross, O.J.2    Mattaj, I.W.3    Karsenti, E.4
  • 5
    • 0033782853 scopus 로고    scopus 로고
    • Spindle assembly in animal cells
    • Compton, D. A. (2000). Spindle assembly in animal cells. Ann. Rev. Biochem. 69, 95-114.
    • (2000) Ann. Rev. Biochem. , vol.69 , pp. 95-114
    • Compton, D.A.1
  • 6
    • 0037162398 scopus 로고    scopus 로고
    • The Ran GTPase: Theme and variations
    • Dasso, M. (2002). The Ran GTPase: theme and variations. Curr Biol 12, R502-R508.
    • (2002) Curr. Biol. , vol.12
    • Dasso, M.1
  • 7
    • 0034682707 scopus 로고    scopus 로고
    • The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement
    • Funabiki, H. and Murray, A. W. (2000). The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement. Cell 102, 411-424.
    • (2000) Cell , vol.102 , pp. 411-424
    • Funabiki, H.1    Murray, A.W.2
  • 8
    • 0034631960 scopus 로고    scopus 로고
    • The Xenopus laevis aurora/Ip11p-related kinase pEg2 participates in the stability of the bipolar mitotic spindle
    • Giet, R. and Prigent, C. (2000). The Xenopus laevis aurora/Ip11p-related kinase pEg2 participates in the stability of the bipolar mitotic spindle. Exp. Cell Res. 258, 145-151.
    • (2000) Exp. Cell Res. , vol.258 , pp. 145-151
    • Giet, R.1    Prigent, C.2
  • 9
    • 0033591432 scopus 로고    scopus 로고
    • The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XIEg5
    • Giet, R., Uzbekov, N., Cubizolles, F., Le Guellec, K. and Prigent, C. (1999). The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XIEg5. J. Biol. Chem. 274, 15005-15013.
    • (1999) J. Biol. Chem. , vol.274 , pp. 15005-15013
    • Giet, R.1    Uzbekov, N.2    Cubizolles, F.3    Le Guellec, K.4    Prigent, C.5
  • 10
    • 0037017398 scopus 로고    scopus 로고
    • Drosophila Aurora A kinase is required to locaize D-TACC to cenuclear transport receptorosomes and to regulate astral microtubules
    • Giet, R., McLean, D. A., Descamps, S., Lee, M. J., Raff, J. W., Prigent, C. and Glover, D. M. (2002). Drosophila Aurora A kinase is required to locaize D-TACC to cenuclear transport receptorosomes and to regulate astral microtubules. J. Cell Biol. 156, 437-451.
    • (2002) J. Cell Biol. , vol.156 , pp. 437-451
    • Giet, R.1    McLean, D.A.2    Descamps, S.3    Lee, M.J.4    Raff, J.W.5    Prigent, C.6    Glover, D.M.7
  • 11
    • 0028938482 scopus 로고
    • Mutations in aurora prevent cenuclear transport receptorosome separation leading to the formation of monopolar spindles
    • Glover, D., Leibowitz, M. H., McLean, D. A. and Parry, H. (1995). Mutations in aurora prevent cenuclear transport receptorosome separation leading to the formation of monopolar spindles. Cell 81, 95-105.
    • (1995) Cell , vol.81 , pp. 95-105
    • Glover, D.1    Leibowitz, M.H.2    McLean, D.A.3    Parry, H.4
  • 13
    • 0035945342 scopus 로고    scopus 로고
    • Aurora-A kinase is required for cenuclear transport receptorosome maturation in Caenorhabditis elegans
    • Hannak, E., Kirkham, M., Hyman, A. A. and Oegema, K. (2001). Aurora-A kinase is required for cenuclear transport receptorosome maturation in Caenorhabditis elegans. J. Cell Biol. 155, 1109-1116.
    • (2001) J. Cell Biol. , vol.155 , pp. 1109-1116
    • Hannak, E.1    Kirkham, M.2    Hyman, A.A.3    Oegema, K.4
  • 14
    • 0033528994 scopus 로고    scopus 로고
    • The ran GTPase regulates mitotic spindle assembly
    • Kalab, P., Pu, R. T. and Dasso, M. C. (1999). The ran GTPase regulates mitotic spindle assembly. Curr. Biol. 9, 481-484.
    • (1999) Curr. Biol. , vol.9 , pp. 481-484
    • Kalab, P.1    Pu, R.T.2    Dasso, M.C.3
  • 15
    • 0037192461 scopus 로고    scopus 로고
    • Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
    • Kalab, P., Weis, K. and Heald, R. (2002). Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. Science 295, 2452-2456.
    • (2002) Science , vol.295 , pp. 2452-2456
    • Kalab, P.1    Weis, K.2    Heald, R.3
  • 17
    • 0035904229 scopus 로고    scopus 로고
    • The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles
    • Levesque, A. A. and Compton, D. A. (2001). The chromokinesin Kid is necessary for chromosome arm orientation and oscillation, but not congression, on mitotic spindles. J. Cell Biol. 154, 1135-1146.
    • (2001) J. Cell Biol. , vol.154 , pp. 1135-1146
    • Levesque, A.A.1    Compton, D.A.2
  • 18
    • 0030462224 scopus 로고    scopus 로고
    • Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization
    • Lounsbury, K., Richards, S., Carey, K. and Macara, I. (1996). Mutations within the Ran/TC4 GTPase. Effects on regulatory factor interactions and subcellular localization. J. Biol. Chem. 271, 32834-32841.
    • (1996) J. Biol. Chem. , vol.271 , pp. 32834-32841
    • Lounsbury, K.1    Richards, S.2    Carey, K.3    Macara, I.4
  • 19
    • 0031707505 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport: The soluble phase
    • Mattaj, I. W. and Englmeier, L. (1998). Nucleocytoplasmic transport: the soluble phase. Ann. Rev. Biochem. 67, 265-306.
    • (1998) Ann. Rev. Biochem. , vol.67 , pp. 265-306
    • Mattaj, I.W.1    Englmeier, L.2
  • 20
    • 0037143453 scopus 로고    scopus 로고
    • Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells
    • Moore, W., Zhang, C. and Clarke, P. R. (2002). Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. Curr. Biol. 12, 1442-1447.
    • (2002) Curr. Biol. , vol.12 , pp. 1442-1447
    • Moore, W.1    Zhang, C.2    Clarke, P.R.3
  • 21
  • 22
    • 0026781685 scopus 로고
    • A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles
    • Nislow, C., Lombillo, V. A., Kuriyama, R. and McIntosh, J. R. (1992). A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles. Nature 359, 543-547.
    • (1992) Nature , vol.359 , pp. 543-547
    • Nislow, C.1    Lombillo, V.A.2    Kuriyama, R.3    McIntosh, J.R.4
  • 23
    • 0033591386 scopus 로고    scopus 로고
    • Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran
    • Ohba, T., Nakamura, M., Nishitani, H. and Nishimoto, T. (1999). Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran. Science 284, 1356-1358.
    • (1999) Science , vol.284 , pp. 1356-1358
    • Ohba, T.1    Nakamura, M.2    Nishitani, H.3    Nishimoto, T.4
  • 24
    • 0036800350 scopus 로고    scopus 로고
    • Xkid chromokinesin is required for the meiosis I to meiosis II transition in Xenopus laevis oocytes
    • Perez, H. L., Antonio, C., Flament, S., Vernos, I. and Nebreda, A. R. (2002). Xkid chromokinesin is required for the meiosis I to meiosis II transition in Xenopus laevis oocytes. Nat. Cell Biol. 4, 737-742.
    • (2002) Nat. Cell Biol. , vol.4 , pp. 737-742
    • Perez, H.L.1    Antonio, C.2    Flament, S.3    Vernos, I.4    Nebreda, A.R.5
  • 25
    • 0031938231 scopus 로고    scopus 로고
    • The Xenopus protein kinase pEg2 associates with the cenuclear transport receptorosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly
    • Roghi, C., Giet, R., Uzbekov, R., Morin, N., Chartrain, I., Le Guellec, R., Couturier, A., Doree, M., Philippe, M. and Prigent, C. (1998). The Xenopus protein kinase pEg2 associates with the cenuclear transport receptorosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly. J. Cell Sci. 111, 557-572.
    • (1998) J. Cell Sci. , vol.111 , pp. 557-572
    • Roghi, C.1    Giet, R.2    Uzbekov, R.3    Morin, N.4    Chartrain, I.5    Le Guellec, R.6    Couturier, A.7    Doree, M.8    Philippe, M.9    Prigent, C.10
  • 26
    • 0031673072 scopus 로고    scopus 로고
    • A highly conserved cenuclear transport receptorosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos
    • Schumacher, J. M., Ashcroft, N., Donovan, P. J. and Golden, A. (1998). A highly conserved cenuclear transport receptorosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos. Development 125, 4391-4402.
    • (1998) Development , vol.125 , pp. 4391-4402
    • Schumacher, J.M.1    Ashcroft, N.2    Donovan, P.J.3    Golden, A.4
  • 27
    • 0037007206 scopus 로고    scopus 로고
    • Human Mps1 kinase is required to the spindle assembly checkpoint but not for cenuclear transport receptorosome duplication
    • Stucke, V. M., Sillje, H. H. W., Arnaud, L. and Nigg, E. A. (2002). Human Mps1 kinase is required to the spindle assembly checkpoint but not for cenuclear transport receptorosome duplication. J. Cell Biol. 21, 1723-1732.
    • (2002) J. Cell Biol. , vol.21 , pp. 1723-1732
    • Stucke, V.M.1    Sillje, H.H.W.2    Arnaud, L.3    Nigg, E.A.4
  • 28
    • 0030046814 scopus 로고    scopus 로고
    • Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle
    • Tokai, N., Fujimoto-Nishiyama, A., Toyoshima, Y., Yonemura, S., Tsukita, S., Inoue, J. and Yamamota, T. (1996). Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle. EMBO J. 15, 457-467.
    • (1996) EMBO J. , vol.15 , pp. 457-467
    • Tokai, N.1    Fujimoto-Nishiyama, A.2    Toyoshima, Y.3    Yonemura, S.4    Tsukita, S.5    Inoue, J.6    Yamamota, T.7
  • 29
    • 0037046808 scopus 로고    scopus 로고
    • Ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos
    • Trieselmann, N. and Wilde, A. (2002). Ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos. Curr. Biol. 12, 1124-1129.
    • (2002) Curr. Biol. , vol.12 , pp. 1124-1129
    • Trieselmann, N.1    Wilde, A.2
  • 31
    • 0031020735 scopus 로고    scopus 로고
    • XCTK2: A kinesin-related protein that promotes mitotic spindle assembly in Xenopus laevis egg extracts
    • Walczak, C. E., Verma, S. and Mitchison, T. J. (1997). XCTK2: a kinesin-related protein that promotes mitotic spindle assembly in Xenopus laevis egg extracts. J. Cell Biol. 136, 859-870.
    • (1997) J. Cell Biol. , vol.136 , pp. 859-870
    • Walczak, C.E.1    Verma, S.2    Mitchison, T.J.3
  • 32
    • 13144251122 scopus 로고    scopus 로고
    • A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bi-polarity
    • Walczak, C. E., Vernos, I., Mitchison, T. J., Karsenti, E. and Heald, R. (1998). A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bi-polarity. Curr. Biol. 8, 903-913.
    • (1998) Curr. Biol. , vol.8 , pp. 903-913
    • Walczak, C.E.1    Vernos, I.2    Mitchison, T.J.3    Karsenti, E.4    Heald, R.5
  • 33
    • 0034609753 scopus 로고    scopus 로고
    • The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
    • Walter, A. O., Seghezzi, W., Korver, W., Sheung, J. and Lees, E. (2000). The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation. Oncogene 19, 4906-4916.
    • (2000) Oncogene , vol.19 , pp. 4906-4916
    • Walter, A.O.1    Seghezzi, W.2    Korver, W.3    Sheung, J.4    Lees, E.5
  • 34
    • 0035951480 scopus 로고    scopus 로고
    • Role of Importin-β in coupling Ran to downstream targets in microtubule assembly
    • Wiese, C., Wilde, A., Moore, M. S., Adam, S. A., Merdes, A. and Zheng, Y. (2001). Role of Importin-β in coupling Ran to downstream targets in microtubule assembly. Science 291, 635-656.
    • (2001) Science , vol.291 , pp. 635-656
    • Wiese, C.1    Wilde, A.2    Moore, M.S.3    Adam, S.A.4    Merdes, A.5    Zheng, Y.6
  • 35
    • 0035090387 scopus 로고    scopus 로고
    • Ran stimulates spindle assembly by changing microtubule dynamics and the balance of motor activities
    • Wilde, A., Lizarraga, S. B., Zhang, L., Wiese, C., Gliksman, N. R., Walczak, C. E. and Zheng, Y. (2001). Ran stimulates spindle assembly by changing microtubule dynamics and the balance of motor activities. Nat. Cell Biol. 3, 221-227.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 221-227
    • Wilde, A.1    Lizarraga, S.B.2    Zhang, L.3    Wiese, C.4    Gliksman, N.R.5    Walczak, C.E.6    Zheng, Y.7
  • 36
    • 0033591373 scopus 로고    scopus 로고
    • Stimulation of microtubule aster and spindle assembly by the small GTPase Ran
    • Wilde, A. and Zheng, Y. (1999). Stimulation of microtubule aster and spindle assembly by the small GTPase Ran. Science 284, 1359-1362.
    • (1999) Science , vol.284 , pp. 1359-1362
    • Wilde, A.1    Zheng, Y.2
  • 37
    • 0034717818 scopus 로고    scopus 로고
    • TPX2, A novel xenopus MAP involved in spindle pole organization
    • Wittmann, T., Wilm, M., Karsenti, E. and Vernos, I. (2000). TPX2, A novel xenopus MAP involved in spindle pole organization. J. Cell Biol. 149, 1405-1418.
    • (2000) J. Cell Biol. , vol.149 , pp. 1405-1418
    • Wittmann, T.1    Wilm, M.2    Karsenti, E.3    Vernos, I.4
  • 38
    • 0034739855 scopus 로고    scopus 로고
    • The role of Xgrip210 in gamma-tubulin ring complex assembly and centrosome recruitment
    • Zhang, L., Keating, T. J., Wilde, A., Borisy, G. G. and Zheng, Y. (2000). The role of Xgrip210 in gamma-tubulin ring complex assembly and centrosome recruitment. J. Cell Biol. 151, 1525-1536.
    • (2000) J. Cell Biol. , vol.151 , pp. 1525-1536
    • Zhang, L.1    Keating, T.J.2    Wilde, A.3    Borisy, G.G.4    Zheng, Y.5
  • 39
    • 0025147718 scopus 로고
    • A kinesin like protein required for distributive segregation in Drosophila
    • Zhang, P., Knowles, B. A., Goldstein, L. S. B. and Hawley, R. S. (1990). A kinesin like protein required for distributive segregation in Drosophila. Cell 62, 1053-1062.
    • (1990) Cell , vol.62 , pp. 1053-1062
    • Zhang, P.1    Knowles, B.A.2    Goldstein, L.S.B.3    Hawley, R.S.4


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