Germline and somatic cancer-associated mutations in the ATP-binding motifs of PTEN influence its subcellular localization and tumor suppressive function

Human Molecular Genetics

Volumn 18, Issue 15, 2009, Pages 2851-2862

  Lobo, Glenn P ^a,c   Waite, Kristin A ^a,b   Planchon, Sarah M ^a   Romigh, Todd ^a   Nassif, Najah T ^d   Eng, Charis ^a,b,c  

^a LERNER RESEARCH INSTITUTE   (United States)

^b TAUSSIG CANCER INSTITUTE   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COLORECTAL CARCINOMA; CONTROLLED STUDY; COWDEN SYNDROME; FEMALE; HUMAN; HUMAN CELL; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; SOMATIC MUTATION;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL LINE, TUMOR; FEMALE; GERM-LINE MUTATION; HAMARTOMA SYNDROME, MULTIPLE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN TRANSPORT; PTEN PHOSPHOHYDROLASE; SEQUENCE ALIGNMENT;

EID: 67650754585     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp220     Document Type: Article

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