메뉴 건너뛰기




Volumn 81, Issue 11, 2002, Pages 623-633

Concentration of Ran on chromatin induces decondensation, nuclear envelope formation and nuclear pore complex assembly

Author keywords

Electron microscopy; Nuclear envelope; Ram; RCCI; Xenopus egg extracts

Indexed keywords

GUANOSINE TRIPHOSPHATASE; NUCLEOTIDE BINDING PROTEIN; RAN PROTEIN; CELL CYCLE PROTEIN; CHC1 PROTEIN, XENOPUS; GUANINE NUCLEOTIDE EXCHANGE FACTOR; NUCLEAR PROTEIN; RCC1 PROTEIN, HUMAN; XENOPUS PROTEIN;

EID: 1842835691     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-9335-00288     Document Type: Article
Times cited : (44)

References (64)
  • 1
    • 0034126815 scopus 로고    scopus 로고
    • The nuclear pore complex: Mediator of translocation between nucleus and cytoplasm
    • Allen, T. D., Cronshaw, J. M., Bagley, S., Kiseleva, E., Goldberg, M. W. (2000); The nuclear pore complex: mediator of translocation between nucleus and cytoplasm. J. Cell Sci. 113, 1651-1659.
    • (2000) J. Cell Sci. , vol.113 , pp. 1651-1659
    • Allen, T.D.1    Cronshaw, J.M.2    Bagley, S.3    Kiseleva, E.4    Goldberg, M.W.5
  • 2
    • 0036006303 scopus 로고    scopus 로고
    • The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo
    • Bamba, C., Bobinnec, Y, Fukuda, M., Nishida, E. (2002); The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo. Curr. Biol. 12, 503-507.
    • (2002) Curr. Biol. , vol.12 , pp. 503-507
    • Bamba, C.1    Bobinnec, Y.2    Fukuda, M.3    Nishida, E.4
  • 4
    • 0028937195 scopus 로고
    • Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1
    • Bischoff, F. R., Krebber, H., Smirnova, E., Dong, W, Ponstingl, H. (1995): Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1. EMBO J. 14, 705-715.
    • (1995) EMBO J. , vol.14 , pp. 705-715
    • Bischoff, F.R.1    Krebber, H.2    Smirnova, E.3    Dong, W.4    Ponstingl, H.5
  • 5
    • 0026419320 scopus 로고
    • Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1
    • Bischoff, F. R., Ponstingl, H. (1991a); Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature 354, 80-82.
    • (1991) Nature , vol.354 , pp. 80-82
    • Bischoff, F.R.1    Ponstingl, H.2
  • 6
    • 0025836659 scopus 로고
    • Mitotic regulator protein RCC1 is complexed with a nuclear Ras-related polypeptide
    • Bischoff, F. R., Ponstingl, H. (1991b): Mitotic regulator protein RCC1 is complexed with a nuclear Ras-related polypeptide. Proc. Natl. Acad. Sci. USA 88, 10830-10834.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10830-10834
    • Bischoff, F.R.1    Ponstingl, H.2
  • 7
    • 0026556684 scopus 로고
    • GTP hydrolysis is required for vesicle fusion during nuclear envelope assembly in vitro
    • Boman, A. L. Delannoy, M. R., Wilson, K. L. (1992): GTP hydrolysis is required for vesicle fusion during nuclear envelope assembly in vitro. J. Cell Biol. 116, 281-294.
    • (1992) J. Cell Biol. , vol.116 , pp. 281-294
    • Boman, A.L.1    Delannoy, M.R.2    Wilson, K.L.3
  • 8
    • 0035090344 scopus 로고    scopus 로고
    • Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly
    • Carazo-Salas, R. E., Gruss, O. J., Mattaj, I. W., Karsenti, E. (2001): Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nature Cell Biol. 3, 228-234.
    • (2001) Nature Cell Biol. , vol.3 , pp. 228-234
    • Carazo-Salas, R.E.1    Gruss, O.J.2    Mattaj, I.W.3    Karsenti, E.4
  • 9
    • 0033536178 scopus 로고    scopus 로고
    • Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation
    • Carazo-Salas, R., Guarguaglini, G., Gruss, O. J., Segref, A., Karsenti, E., Mattaj, I. W. (1999): Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 400, 178-181.
    • (1999) Nature , vol.400 , pp. 178-181
    • Carazo-Salas, R.1    Guarguaglini, G.2    Gruss, O.J.3    Segref, A.4    Karsenti, E.5    Mattaj, I.W.6
  • 10
    • 0001506297 scopus 로고    scopus 로고
    • Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp
    • Chook, Y. M., Blobel, G. (1999): Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp. Nature 399, 230-237.
    • (1999) Nature , vol.399 , pp. 230-237
    • Chook, Y.M.1    Blobel, G.2
  • 11
    • 0028910594 scopus 로고
    • Regulation of cdc2/cyclin B activation by Ran, a Ras-related GTPase
    • Clarke, P. R., Klebe, C., Wittinghofer, A., Karsenti, E. (1995): Regulation of cdc2/cyclin B activation by Ran, a Ras-related GTPase. J. Cell Sci. 108, 1217-1225.
    • (1995) J. Cell Sci. , vol.108 , pp. 1217-1225
    • Clarke, P.R.1    Klebe, C.2    Wittinghofer, A.3    Karsenti, E.4
  • 12
    • 0035445281 scopus 로고    scopus 로고
    • Ran GTPase: A master regulator of nuclear structure and function during the eukaryotic cell division cycle?
    • Clarke, P. R., Zhang, C. (2001): Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle? Trends Cell Biol. 11, 366-371.
    • (2001) Trends Cell Biol. , vol.11 , pp. 366-371
    • Clarke, P.R.1    Zhang, C.2
  • 13
    • 0027732054 scopus 로고
    • Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4
    • Coutavas, E , Ren, M,, Oppenheim, J. D., D'Eustachio, P., Rush, M. G. (1993): Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4. Nature 366, 585-587.
    • (1993) Nature , vol.366 , pp. 585-587
    • Coutavas, E.1    Ren, M.2    Oppenheim, J.D.3    D'Eustachio, P.4    Rush, M.G.5
  • 14
    • 0035830499 scopus 로고    scopus 로고
    • Running on Ran: Nuclear transport and the mitotic spindle
    • Dasso, M. (2001): Running on Ran: Nuclear transport and the mitotic spindle. Cell 104, 321-324.
    • (2001) Cell , vol.104 , pp. 321-324
    • Dasso, M.1
  • 15
    • 0027938043 scopus 로고
    • A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation
    • Dasso, M., Seki, T., Azuma, Y., Ohba, T, Nishimoto, T. (1994): A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation. EMBO J. 13, 5732-5744.
    • (1994) EMBO J. , vol.13 , pp. 5732-5744
    • Dasso, M.1    Seki, T.2    Azuma, Y.3    Ohba, T.4    Nishimoto, T.5
  • 16
    • 0023449881 scopus 로고
    • Nuclear pore complex contains a family of glycoproteins that includes p62: Glycosylation through a previously unidentified cellular pathway
    • Davies, L. I., Blobel, G. (1987): Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway. Proc. Natl. Acad. Sci. USA 84, 7552-7556.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7552-7556
    • Davies, L.I.1    Blobel, G.2
  • 17
    • 0028907320 scopus 로고
    • A mutation in the RCC1-related protein pim1 results in nuclear envelope fragmentation in fission: Yeast
    • Demeter, J., Morphew, M., Sazer, S. (1995). A mutation in the RCC1-related protein pim1 results in nuclear envelope fragmentation in fission: yeast. Proc. Natl. Acad. Sci. USA 92, 1436-1440.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1436-1440
    • Demeter, J.1    Morphew, M.2    Sazer, S.3
  • 20
    • 0033279841 scopus 로고    scopus 로고
    • Transport between the cell nucleus and the cytoplasm
    • Görlich, D., Kutay, U. (1999): Transport between the cell nucleus and the cytoplasm. Annu. Rev. Cell Dev. Biol. 15, 607-660.
    • (1999) Annu. Rev. Cell Dev. Biol. , vol.15 , pp. 607-660
    • Görlich, D.1    Kutay, U.2
  • 21
    • 0029984570 scopus 로고    scopus 로고
    • Nucleocytoplasmic transport
    • Görlich, D., Mattaj, I. W. (1996): Nucleocytoplasmic transport. Science 271, 1513-1518.
    • (1996) Science , vol.271 , pp. 1513-1518
    • Görlich, D.1    Mattaj, I.W.2
  • 24
    • 0031771883 scopus 로고    scopus 로고
    • The role of Ran GTPase in nuclear assembly and DNA replication: Characterisation of the effects of Ran mutants
    • Hughes, M., Zhang, C., Avis, J. M., Hutchison, C. J., Clarke, P. R. (1998): The role of Ran GTPase in nuclear assembly and DNA replication: characterisation of the effects of Ran mutants. J. Cell Sci. 111, 3017-3026.
    • (1998) J. Cell Sci. , vol.111 , pp. 3017-3026
    • Hughes, M.1    Zhang, C.2    Avis, J.M.3    Hutchison, C.J.4    Clarke, P.R.5
  • 25
    • 0001816058 scopus 로고
    • The use of cell-free extracts of Xenopus laevis eggs for studying DNA replication in vitro
    • P Fantes, R. Brooks (eds.): IRL Press, Oxford
    • Hutchison, C. J. (1994). The use of cell-free extracts of Xenopus laevis eggs for studying DNA replication in vitro. In: P Fantes, R. Brooks (eds.): The cell cycle: a practical approach. Pp. 177-195. IRL Press, Oxford.
    • (1994) The Cell Cycle: A Practical Approach , pp. 177-195
    • Hutchison, C.J.1
  • 26
    • 0030856315 scopus 로고    scopus 로고
    • The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus
    • Izaurralde, E., Kutay, U., von Kobbe, C., Mattaj, I. W, Görlich, D. (1997): The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus. EMBO J. 16, 6535-6547.
    • (1997) EMBO J. , vol.16 , pp. 6535-6547
    • Izaurralde, E.1    Kutay, U.2    von Kobbe, C.3    Mattaj, I.W.4    Görlich, D.5
  • 27
    • 0033528994 scopus 로고    scopus 로고
    • The Ran GTPase regulates mitotic spindle assembly
    • Kalab, P., Pu, R. T., Dasso, M. (1999): The Ran GTPase regulates mitotic spindle assembly. Curr. Biol. 9, 1481-484.
    • (1999) Curr. Biol. , vol.9 , pp. 1481-1484
    • Kalab, P.1    Pu, R.T.2    Dasso, M.3
  • 28
    • 0037192461 scopus 로고    scopus 로고
    • Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
    • Kalab, P, Weis, K., Heald, R. (2002): Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. Science 295, 2452-2456.
    • (2002) Science , vol.295 , pp. 2452-2456
    • Kalab, P.1    Weis, K.2    Heald, R.3
  • 29
    • 0028964821 scopus 로고
    • Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCCI and RanGAP1
    • Klebe, C., Bischoff, F. R., Ponstingl, H., Wittinghofer, A. (1995a). Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCCI and RanGAP1. Biochemistry 34, 639-647.
    • (1995) Biochemistry , vol.34 , pp. 639-647
    • Klebe, C.1    Bischoff, F.R.2    Ponstingl, H.3    Wittinghofer, A.4
  • 30
    • 0028801195 scopus 로고
    • The kinetic mechanism of Ran-nucleotide exchange catalyzed by, RCC1
    • Klebe, C., Prinz, H., Wittinghofer, A., Goody, R. S. (19956): The kinetic mechanism of Ran-nucleotide exchange catalyzed by, RCC1. Biochemistry 34, 12543-12552.
    • (1995) Biochemistry , vol.34 , pp. 12543-12552
    • Klebe, C.1    Prinz, H.2    Wittinghofer, A.3    Goody, R.S.4
  • 31
    • 0030047960 scopus 로고    scopus 로고
    • Assembly of the nuclear pore: Biochemically distinct steps revealed with NEM, GTP gamma S, and BAPTA
    • Macaulay, C., Forbes, D. J. (1996): Assembly of the nuclear pore: biochemically distinct steps revealed with NEM, GTP gamma S, and BAPTA. J. Cell Biol. 132, 5-20.
    • (1996) J. Cell Biol. , vol.132 , pp. 5-20
    • Macaulay, C.1    Forbes, D.J.2
  • 32
    • 0030932134 scopus 로고    scopus 로고
    • A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2
    • Mahajan, R., Delphin, C., Guan, T., Gerace, L., Melchior, F. (1997): A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell 88, 97-107.
    • (1997) Cell , vol.88 , pp. 97-107
    • Mahajan, R.1    Delphin, C.2    Guan, T.3    Gerace, L.4    Melchior, F.5
  • 33
    • 0031081298 scopus 로고    scopus 로고
    • Nuclear envelope assembly after mitosis
    • Marshall, I. C. B., Wilson, K. L. (1997): Nuclear envelope assembly after mitosis. Trends Cell Biol. 7, 69-73.
    • (1997) Trends Cell Biol. , vol.7 , pp. 69-73
    • Marshall, I.C.B.1    Wilson, K.L.2
  • 34
    • 0030455748 scopus 로고    scopus 로고
    • A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex
    • Matunis, M. J., Coutavas, E., Blobel, G. (1996): A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex. J. Cell Biol. 135, 1457-1470.
    • (1996) J. Cell Biol. , vol.135 , pp. 1457-1470
    • Matunis, M.J.1    Coutavas, E.2    Blobel, G.3
  • 35
    • 0037143453 scopus 로고    scopus 로고
    • Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells
    • Moore, W. J., Zhang, C., Clarke, P. R. (2002): Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells. Curr. Biol. 12, 1442-1447.
    • (2002) Curr. Biol. , vol.12 , pp. 1442-1447
    • Moore, W.J.1    Zhang, C.2    Clarke, P.R.3
  • 36
    • 0033578298 scopus 로고    scopus 로고
    • The direction of transport through the nuclear pore can be inverted
    • Nachury, M. V, Weis, K. (1999): The direction of transport through the nuclear pore can be inverted. Proc. Natl. Acad. Sci. USA 96, 9622-9627.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9622-9627
    • Nachury, M.V.1    Weis, K.2
  • 37
    • 0034658460 scopus 로고    scopus 로고
    • Nuclear import of the Ran exchange factor, RCC1, is mediated by at least two distinct mechanisms
    • Nemergut, M. E., Macara, I. G. (2000): Nuclear import of the Ran exchange factor, RCC1, is mediated by at least two distinct mechanisms. J. Cell Biol. 149, 835-850.
    • (2000) J. Cell Biol. , vol.149 , pp. 835-850
    • Nemergut, M.E.1    Macara, I.G.2
  • 38
    • 0035947299 scopus 로고    scopus 로고
    • Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B
    • Nemergut, M. E., Mizzen, C. A., Stukenberg, T, Allis, C. D., Macara, I. G. (2001): Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B. Science 292, 1540-1543.
    • (2001) Science , vol.292 , pp. 1540-1543
    • Nemergut, M.E.1    Mizzen, C.A.2    Stukenberg, T.3    Allis, C.D.4    Macara, I.G.5
  • 39
    • 0026501103 scopus 로고
    • Characterization of the membrane binding and fusion events during nuclear envelope assembly using purified components
    • Newport, J., Dunphy, W. (1992): Characterization of the membrane binding and fusion events during nuclear envelope assembly using purified components. J. Cell Biol. 116, 295-306.
    • (1992) J. Cell Biol. , vol.116 , pp. 295-306
    • Newport, J.1    Dunphy, W.2
  • 40
    • 0034851679 scopus 로고    scopus 로고
    • XMog1, a nuclear Ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe Mog1p that co-operates with RanBP1 to control generation of Ran-GTP
    • Nicolás, F. J., Moore, W. J., Zhang, C., Clarke, P. R. (2001): XMog1, a nuclear Ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe Mog1p that co-operates with RanBP1 to control generation of Ran-GTP. J. Cell Sci. 114, 3013-3023.
    • (2001) J. Cell Sci. , vol.114 , pp. 3013-3023
    • Nicolás, F.J.1    Moore, W.J.2    Zhang, C.3    Clarke, P.R.4
  • 41
    • 0031455287 scopus 로고    scopus 로고
    • Xenopus Ran-binding protein 1: Molecular interactions and effects on nuclear assembly in Xenopus egg extracts
    • Nicolás, F. J., Zhang, C., Hughes, M., Goldberg, M. W., Watton, S. J., Clarke, P. R. (1997): Xenopus Ran-binding protein 1: molecular interactions and effects on nuclear assembly in Xenopus egg extracts. J. Cell Sci. 110, 3019-3030.
    • (1997) J. Cell Sci. , vol.110 , pp. 3019-3030
    • Nicolás, F.J.1    Zhang, C.2    Hughes, M.3    Goldberg, M.W.4    Watton, S.J.5    Clarke, P.R.6
  • 42
    • 0033591386 scopus 로고    scopus 로고
    • Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran
    • Ohba, T., Nakamura, M., Nishitani, H., Nishimoto, T. (1999): Self-organization of microtubule asters induced in Xenopus egg extracts by GTP-bound Ran. Science 284, 1356-1358.
    • (1999) Science , vol.284 , pp. 1356-1358
    • Ohba, T.1    Nakamura, M.2    Nishitani, H.3    Nishimoto, T.4
  • 43
    • 0024445582 scopus 로고
    • The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA
    • Ohtsubo, M., Okazaki, H., Nishimoto, T. (1989): The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA. J. Cell Biol. 109, 1389-1397.
    • (1989) J. Cell Biol. , vol.109 , pp. 1389-1397
    • Ohtsubo, M.1    Okazaki, H.2    Nishimoto, T.3
  • 44
    • 0034056775 scopus 로고    scopus 로고
    • Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1
    • Plafker, K., Macara, I. G. (2000): Facilitated nucleocytoplasmic shuttling of the Ran binding protein RanBP1. Mol. Cell. Biol. 20, 3510-3521.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3510-3521
    • Plafker, K.1    Macara, I.G.2
  • 45
    • 0030775005 scopus 로고    scopus 로고
    • The balance of RanBP1 and RCC1 is critical for nuclear assembly and nuclear transport
    • Pu, R. T, Dasso, M. (1997): The balance of RanBP1 and RCC1 is critical for nuclear assembly and nuclear transport. Mol. Biol. Cell 8, 1955-1970.
    • (1997) Mol. Biol. Cell , vol.8 , pp. 1955-1970
    • Pu, R.T.1    Dasso, M.2
  • 46
    • 0027389003 scopus 로고
    • Ran/TC4: A small nuclear GTP-binding protein that regulates DNA synthesis
    • Ren, M., Drivas, G., D'Eustachio, P, Rush, M. G. (1993): Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis. J. Cell Biol. 120, 313-323.
    • (1993) J. Cell Biol. , vol.120 , pp. 313-323
    • Ren, M.1    Drivas, G.2    D'Eustachio, P.3    Rush, M.G.4
  • 48
    • 0029738481 scopus 로고    scopus 로고
    • A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1
    • Richards, S. A., Lounsbury, K. M., Carey, K. L., Macara, I. G. (1996): A nuclear export signal is essential for the cytosolic localization of the Ran binding protein, RanBP1. J. Cell Biol. 134, 1157-1168.
    • (1996) J. Cell Biol. , vol.134 , pp. 1157-1168
    • Richards, S.A.1    Lounsbury, K.M.2    Carey, K.L.3    Macara, I.G.4
  • 49
    • 0030087693 scopus 로고    scopus 로고
    • The small nuclear GTPase Ran: How much does it run?
    • Rush, M. G., Drivas, G., D'Eustachio, P. D. (1996): The small nuclear GTPase Ran: how much does it run? Bioessays 18, 103-112.
    • (1996) Bioessays , vol.18 , pp. 103-112
    • Rush, M.G.1    Drivas, G.2    D'Eustachio, P.D.3
  • 50
    • 0030046910 scopus 로고    scopus 로고
    • The search for the primary function of the Ran GTPase continues
    • Sazer, S. (1996): The search for the primary function of the Ran GTPase continues. Trends Cell Biol. 6, 81-85.
    • (1996) Trends Cell Biol. , vol.6 , pp. 81-85
    • Sazer, S.1
  • 51
    • 0028009578 scopus 로고
    • A fission yeast RCC1-related protein is required for the mitosis to interphase transition
    • Sazer, S., Nurse, P. (1994): A fission yeast RCC1-related protein is required for the mitosis to interphase transition. EMBO 113, 606-615.
    • (1994) EMBO , vol.113 , pp. 606-615
    • Sazer, S.1    Nurse, P.2
  • 52
    • 0028929866 scopus 로고
    • Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form
    • Scheffzek, K., Klebe, C., Fritz-Wolf, K., Kabsch, W., Wittinghofer, A. (1995). Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form. Nature 374, 378-381.
    • (1995) Nature , vol.374 , pp. 378-381
    • Scheffzek, K.1    Klebe, C.2    Fritz-Wolf, K.3    Kabsch, W.4    Wittinghofer, A.5
  • 53
    • 0032585533 scopus 로고    scopus 로고
    • Nuclear import of Ran is mediated by the transport factor NTF2
    • Smith, A., Brownawell, A., Macara, I. G. (1998): Nuclear import of Ran is mediated by the transport factor NTF2. Curr. Biol. 8, 1403-1406.
    • (1998) Curr. Biol. , vol.8 , pp. 1403-1406
    • Smith, A.1    Brownawell, A.2    Macara, I.G.3
  • 54
    • 0034616123 scopus 로고    scopus 로고
    • The nuclear import of RCC1 requires a specific nuclear localisation sequence receptor, karyopherin α3/Qip
    • Talcott, B., Moore, M. S. (2000): The nuclear import of RCC1 requires a specific nuclear localisation sequence receptor, karyopherin α3/Qip. J. Biol. Chem. 275, 10099-10104.
    • (2000) J. Biol. Chem. , vol.275 , pp. 10099-10104
    • Talcott, B.1    Moore, M.S.2
  • 55
    • 0033612390 scopus 로고    scopus 로고
    • Structural view of the Ran-importin beta interaction at 2.3 Å resolution
    • Vetter, I. R., Arndt, A., Kutay, U., Görlich, D., Wittinghofer, A. (1999a): Structural view of the Ran-importin beta interaction at 2.3 Å resolution. Cell 97, 635-646.
    • (1999) Cell , vol.97 , pp. 635-646
    • Vetter, I.R.1    Arndt, A.2    Kutay, U.3    Görlich, D.4    Wittinghofer, A.5
  • 56
    • 0033522118 scopus 로고    scopus 로고
    • Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: Implications for nuclear transport
    • Vetter, I. R., Nowak, C., Nishimoto, T., Kuhlmann, J., Wittinghofer, A. (1999b): Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport. Nature 398, 39-46.
    • (1999) Nature , vol.398 , pp. 39-46
    • Vetter, I.R.1    Nowak, C.2    Nishimoto, T.3    Kuhlmann, J.4    Wittinghofer, A.5
  • 57
    • 0030794456 scopus 로고    scopus 로고
    • Nuclear envelope assembly in Xenopus extracts visualized by scanning EM reveals a transport-dependent 'envelope smoothing' event
    • Wiese, C., Goldberg, M. W., Allen, T. D., Wilson, K. L. (1997): Nuclear envelope assembly in Xenopus extracts visualized by scanning EM reveals a transport-dependent 'envelope smoothing' event. J. Cell Sci. 110, 1489-1502.
    • (1997) J. Cell Sci. , vol.110 , pp. 1489-1502
    • Wiese, C.1    Goldberg, M.W.2    Allen, T.D.3    Wilson, K.L.4
  • 58
    • 0035951480 scopus 로고    scopus 로고
    • Role of importin-β in coupling Ran to downstream targets in microtubule assembly
    • Wiese, C., Wilde, A., Moore, M. S., Adam, S. A., Merdes, A., Zheng, Y. (2001): Role of importin-β in coupling Ran to downstream targets in microtubule assembly. Science 291, 653-656.
    • (2001) Science , vol.291 , pp. 653-656
    • Wiese, C.1    Wilde, A.2    Moore, M.S.3    Adam, S.A.4    Merdes, A.5    Zheng, Y.6
  • 59
    • 0035090387 scopus 로고    scopus 로고
    • Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities
    • Wilde, A., Lizarraga, S. B., Zhang, L., Wiese, C., Gliksman, N. R., Walczak, C. E., Zheng, Y. (2001): Ran stimulates spindle assembly by altering microtubule dynamics and the balance of motor activities. Nature Cell Biol. 3, 221-227.
    • (2001) Nature Cell Biol. , vol.3 , pp. 221-227
    • Wilde, A.1    Lizarraga, S.B.2    Zhang, L.3    Wiese, C.4    Gliksman, N.R.5    Walczak, C.E.6    Zheng, Y.7
  • 60
    • 0033591373 scopus 로고    scopus 로고
    • Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran
    • Wilde, A., Zheng, Y. (1999): Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. Science 284, 1362-1365.
    • (1999) Science , vol.284 , pp. 1362-1365
    • Wilde, A.1    Zheng, Y.2
  • 61
    • 0034717035 scopus 로고    scopus 로고
    • Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts
    • Zhang, C., Clarke, P. R. (2000): Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts. Science 288, 1429-1432.
    • (2000) Science , vol.288 , pp. 1429-1432
    • Zhang, C.1    Clarke, P.R.2
  • 62
    • 0035128451 scopus 로고    scopus 로고
    • Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system
    • Zhang, C., Clarke, P. R. (2001): Roles of Ran-GTP and Ran-GDP in precursor vesicle recruitment and fusion during nuclear envelope assembly in a human cell-free system. Curr. Biol. 11, 208-212.
    • (2001) Curr. Biol. , vol.11 , pp. 208-212
    • Zhang, C.1    Clarke, P.R.2
  • 63
    • 0032814745 scopus 로고    scopus 로고
    • Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts
    • Zhang, C., Hughes, M., Clarke, P. R. (1999): Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts. J. Cell Sci. 112, 2453-2461.
    • (1999) J. Cell Sci. , vol.112 , pp. 2453-2461
    • Zhang, C.1    Hughes, M.2    Clarke, P.R.3
  • 64
    • 0036006299 scopus 로고    scopus 로고
    • Role of importin-beta in the control of nuclear envelope assembly by Ran
    • Zhang, C., Hutchins, J. R., Muhlhausser, P., Kutay, U., Clarke, P. R. (2002): Role of importin-beta in the control of nuclear envelope assembly by Ran. Curr. Biol. 12, 498-502.
    • (2002) Curr. Biol. , vol.12 , pp. 498-502
    • Zhang, C.1    Hutchins, J.R.2    Muhlhausser, P.3    Kutay, U.4    Clarke, P.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.