Activation of the ran GTPase is subject to growth factor regulation and can give rise to cellular transformation

Journal of Biological Chemistry

Volumn 285, Issue 8, 2010, Pages 5815-5826

  Ly, Thi K ^a   Wang, Jianbin ^a   Pereira, Ryan ^a   Rojas, Katherine S ^a   Peng, Xu ^a   Feng, Qiyu ^a   Cerione, Richard A ^a   Wilson, Kristin F ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAP-BINDING COMPLEXES; CELLULAR TRANSFORMATION; EPIDERMAL GROWTH FACTOR RECEPTORS; GROWTH FACTOR; GROWTH FACTOR REGULATION; HEREGULIN; HUMAN BREAST CANCER CELLS; IN-CELL; MAMMALIAN TARGET; MITOTIC SPINDLE; NUCLEAR ENVELOPE FORMATION; NUCLEOCYTOPLASMIC TRANSPORT; OVER-EXPRESSION; PATIENT PROGNOSIS; RNA BINDING; TYROSINE KINASE;

AMINO ACIDS; ANTIBIOTICS; BIOACTIVITY; GENE EXPRESSION; GROWTH KINETICS; MAMMALS; PEPTIDES; PHOSPHATASES; RNA; TUMORS;

CELL GROWTH;

CAP BINDING PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MAMMALIAN TARGET OF RAPAMYCIN; NEU DIFFERENTIATION FACTOR; RAN PROTEIN; ERBB2 PROTEIN, HUMAN; ERBB2 PROTEIN, MOUSE; MESSENGER RNA; NRG1 PROTEIN, HUMAN; NRG1 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; RAN PROTEIN, HUMAN; RAN PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CARCINOGENESIS; CELL GROWTH; CELL STRAIN 3T3; CELL TRANSFORMATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GROWTH REGULATION; HUMAN; HUMAN CELL; MALE; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA BINDING; RNA PROCESSING; ANIMAL; BIOSYNTHESIS; BREAST TUMOR; CELL NUCLEUS; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; FEMALE; GENETICS; METABOLISM; MUTATION; TUMOR CELL LINE;

MAMMALIA; MUS;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; ENZYME ACTIVATION; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MUTATION; NEUREGULIN-1; NIH 3T3 CELLS; PROTEIN-SERINE-THREONINE KINASES; RAN GTP-BINDING PROTEIN; RECEPTOR, ERBB-2; RNA CAP-BINDING PROTEINS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER;

EID: 77949326178     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.071886     Document Type: Article

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