RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism

PLoS Genetics

Volumn 2, Issue 10, 2006, Pages 1653-1665

  Aslanukov, Azamat ^a,g   Bhowmick, Reshma ^b   Guruju, Mallikarjuna ^c   Oswald, John ^c   Raz, Dorit ^d   Bush, Ronald A ^d   Sieving, Paul A ^e   Lu, Xinrong ^c   Bock, Cheryl B ^f   Ferreira, Paulo A ^c  

^a Third Wave Technologies Inc   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^e NATIONAL EYE INSTITUTE   (United States)

^f DUKE CANCER INSTITUTE   (United States)

^g Fugent LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BINDING PROTEIN; CHAPERONE; HEXOKINASE; HEXOKINASE 1 ENZYME; LEUCINE; PROTEIN COX11; PROTEIN RAN BINDING PROTEIN 2; UNCLASSIFIED DRUG; COX11 PROTEIN, MOUSE; GLUCOSE; HEAT SHOCK PROTEIN 70; HEXOKINASE 1 PROTEIN, MOUSE; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; NUCLEOPORIN; RAN BINDING PROTEIN 2; RAN-BINDING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; CYTOSOL; DISORDERS OF CARBOHYDRATE METABOLISM; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; GENE LOCUS; GLUCONEOGENESIS; GLUCOSE TRANSPORT; GLYCOLYSIS; GROWTH RATE; HEART FUNCTION TEST; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PACEMAKER; PATHOPHYSIOLOGY; PHENOTYPE; PHOTOSENSITIZATION; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; RETINA NERVE CELL; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CHEMISTRY; CYTOLOGY; ELECTRORETINOGRAPHY; GENE EXPRESSION REGULATION; GENETICS; HAPLOIDY; METABOLISM; MOLECULAR GENETICS; MOUSE MUTANT; PHOTORECEPTOR; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; ELECTRORETINOGRAPHY; GLUCOSE; HAPLOIDY; HEXOKINASE; HSP70 HEAT-SHOCK PROTEINS; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; NUCLEAR PORE COMPLEX PROTEINS; PHENOTYPE; PHOTORECEPTORS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33750429598     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0020177     Document Type: Article

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