메뉴 건너뛰기




Volumn 26, Issue 1, 2013, Pages 50-63

Novel non-canonical TGF-β signaling networks: Emerging roles in airway smooth muscle phenotype and function

Author keywords

Asthma; Autophagy; Calcium; Chronic obstructive pulmonary disease; HMGB1; PI3K signaling; S100 proteins; WNT catenin signaling

Indexed keywords

2 (6 AMINO 9 PURINYLMETHYL) 5 METHYL 3 (2 METHYLPHENYL) 3H QUINAZOLIN 4 ONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 9 (1 ANILINOETHYL) 7 METHYL 2 MORPHOLINOPYRIDO[1,2 A]PYRIMIDIN 4 ONE; ADVANCED GLYCATION END PRODUCT RECEPTOR; ALPHA SMOOTH MUSCLE ACTIN; BETA CATENIN; CALCIUM ION; CALPONIN; CHEMOKINE; COLLAGEN; CONNECTIVE TISSUE GROWTH FACTOR; CYTOKINE; FIBRONECTIN; LYMPHOID ENHANCER FACTOR 1; MAMMALIAN TARGET OF RAPAMYCIN; MATRIX PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NIFEDIPINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PIK 75; PROTEIN P70; PROTEOGLYCAN; RYANODINE; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; WNT PROTEIN;

EID: 84873157043     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2012.07.006     Document Type: Article
Times cited : (42)

References (187)
  • 2
    • 0033036099 scopus 로고    scopus 로고
    • Role of transforming growth factor beta type II receptor in hepatic fibrosis: studies of human chronic hepatitis C and experimental fibrosis in rats
    • Roulot D., Sevcsik A.M., Coste T., Strosberg A.D., Marullo S. Role of transforming growth factor beta type II receptor in hepatic fibrosis: studies of human chronic hepatitis C and experimental fibrosis in rats. Hepatology 1999, 29:1730-1738.
    • (1999) Hepatology , vol.29 , pp. 1730-1738
    • Roulot, D.1    Sevcsik, A.M.2    Coste, T.3    Strosberg, A.D.4    Marullo, S.5
  • 5
    • 0023732890 scopus 로고
    • Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide
    • Gentry L.E., Lioubin M.N., Purchio A.F., Marquardt H. Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide. Mol Cell Biol 1988, 8:4162-4168.
    • (1988) Mol Cell Biol , vol.8 , pp. 4162-4168
    • Gentry, L.E.1    Lioubin, M.N.2    Purchio, A.F.3    Marquardt, H.4
  • 6
    • 0033532054 scopus 로고    scopus 로고
    • The activation sequence of thrombospondin-1 interacts with the latency-associated peptide to regulate activation of latent transforming growth factor-beta
    • Ribeiro S.M., Poczatek M., Schultz-Cherry S., Villain M., Murphy-Ullrich J.E. The activation sequence of thrombospondin-1 interacts with the latency-associated peptide to regulate activation of latent transforming growth factor-beta. J Biol Chem 1999, 274:13586-13593.
    • (1999) J Biol Chem , vol.274 , pp. 13586-13593
    • Ribeiro, S.M.1    Poczatek, M.2    Schultz-Cherry, S.3    Villain, M.4    Murphy-Ullrich, J.E.5
  • 7
    • 0037435009 scopus 로고    scopus 로고
    • Loss of integrin alpha(V)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema
    • Morris D.G., Huang X., Kaminski N., Wang Y., Shapiro S.D., Dolganov G., et al. Loss of integrin alpha(V)beta6-mediated TGF-beta activation causes Mmp12-dependent emphysema. Nature 2003, 422:169-173.
    • (2003) Nature , vol.422 , pp. 169-173
    • Morris, D.G.1    Huang, X.2    Kaminski, N.3    Wang, Y.4    Shapiro, S.D.5    Dolganov, G.6
  • 8
    • 28744437302 scopus 로고    scopus 로고
    • TGF-beta signal transduction in oro-facial health and non-malignant disease (Part I)
    • Prime S.S., Pring M., Davies M., Paterson I.C. TGF-beta signal transduction in oro-facial health and non-malignant disease (Part I). Crit Rev Oral Biol Med 2004, 15:324-336.
    • (2004) Crit Rev Oral Biol Med , vol.15 , pp. 324-336
    • Prime, S.S.1    Pring, M.2    Davies, M.3    Paterson, I.C.4
  • 9
    • 1642473157 scopus 로고    scopus 로고
    • The transforming growth factor-beta superfamily of receptors
    • de Caestecker M. The transforming growth factor-beta superfamily of receptors. Cytokine Growth Factor Rev 2004, 15:1-11.
    • (2004) Cytokine Growth Factor Rev , vol.15 , pp. 1-11
    • de Caestecker, M.1
  • 10
    • 0032763469 scopus 로고    scopus 로고
    • Specificity, diversity, and regulation in TGF-beta superfamily signaling
    • Piek E., Heldin C.H., Ten Dijke P. Specificity, diversity, and regulation in TGF-beta superfamily signaling. FASEB J 1999, 13:2105-2124.
    • (1999) FASEB J , vol.13 , pp. 2105-2124
    • Piek, E.1    Heldin, C.H.2    Ten Dijke, P.3
  • 11
    • 0036197606 scopus 로고    scopus 로고
    • Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small Gtpases Cdc42 and Rhoa
    • Edlund S., Landstrom M., Heldin C.H., Aspenstrom P. Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small Gtpases Cdc42 and Rhoa. Mol Biol Cell 2002, 13:902-914.
    • (2002) Mol Biol Cell , vol.13 , pp. 902-914
    • Edlund, S.1    Landstrom, M.2    Heldin, C.H.3    Aspenstrom, P.4
  • 12
    • 0041883785 scopus 로고    scopus 로고
    • Smad3 and Pkcdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells
    • Runyan C.E., Schnaper H.W., Poncelet A.C. Smad3 and Pkcdelta mediate TGF-beta1-induced collagen I expression in human mesangial cells. Am J Physiol Ren Physiol 2003, 285:F413-F422.
    • (2003) Am J Physiol Ren Physiol , vol.285
    • Runyan, C.E.1    Schnaper, H.W.2    Poncelet, A.C.3
  • 13
    • 0032868499 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase is required for growth factor-induced amino acid uptake by vascular smooth muscle cells
    • Higaki M., Shimokado K. Phosphatidylinositol 3-kinase is required for growth factor-induced amino acid uptake by vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 1999, 19:2127-2132.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 2127-2132
    • Higaki, M.1    Shimokado, K.2
  • 14
    • 0031035582 scopus 로고    scopus 로고
    • Evidence for a role of rho-like Gtpases and stress-activated protein kinase/C-Jun N-terminal kinase (Sapk/Jnk) in transforming growth factor beta-mediated signaling
    • Atfi A., Djelloul S., Chastre E., Davis R., Gespach C. Evidence for a role of rho-like Gtpases and stress-activated protein kinase/C-Jun N-terminal kinase (Sapk/Jnk) in transforming growth factor beta-mediated signaling. J Biol Chem 1997, 272:1429-1432.
    • (1997) J Biol Chem , vol.272 , pp. 1429-1432
    • Atfi, A.1    Djelloul, S.2    Chastre, E.3    Davis, R.4    Gespach, C.5
  • 15
    • 0032495987 scopus 로고    scopus 로고
    • The role of P38 map kinase in TGF-beta1-induced signal transduction in human neutrophils
    • Hannigan M., Zhan L., Ai Y., Huang C.K. The role of P38 map kinase in TGF-beta1-induced signal transduction in human neutrophils. Biochem Biophys Res Commun 1998, 246:55-58.
    • (1998) Biochem Biophys Res Commun , vol.246 , pp. 55-58
    • Hannigan, M.1    Zhan, L.2    Ai, Y.3    Huang, C.K.4
  • 17
    • 47049131867 scopus 로고    scopus 로고
    • Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of P300
    • Hirota M., Watanabe K., Hamada S., Sun Y., Strizzi L., Mancino M., et al. Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of P300. Cell Signal 2008, 20:1632-1641.
    • (2008) Cell Signal , vol.20 , pp. 1632-1641
    • Hirota, M.1    Watanabe, K.2    Hamada, S.3    Sun, Y.4    Strizzi, L.5    Mancino, M.6
  • 18
    • 79961139550 scopus 로고    scopus 로고
    • TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions
    • Santibanez J.F., Quintanilla M., Bernabeu C. TGF-beta/TGF-beta receptor system and its role in physiological and pathological conditions. Clin Sci (Lond) 2011, 121:233-251.
    • (2011) Clin Sci (Lond) , vol.121 , pp. 233-251
    • Santibanez, J.F.1    Quintanilla, M.2    Bernabeu, C.3
  • 19
    • 23244456978 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 and disorders of the lung
    • Camoretti-Mercado B., Solway J. Transforming growth factor-beta1 and disorders of the lung. Cell Biochem Biophys 2005, 43:131-148.
    • (2005) Cell Biochem Biophys , vol.43 , pp. 131-148
    • Camoretti-Mercado, B.1    Solway, J.2
  • 20
    • 33646746153 scopus 로고    scopus 로고
    • TGF-beta: its role in asthma and therapeutic potential
    • Howell J.E., McAnulty R.J. TGF-beta: its role in asthma and therapeutic potential. Curr Drug Targets 2006, 7:547-565.
    • (2006) Curr Drug Targets , vol.7 , pp. 547-565
    • Howell, J.E.1    McAnulty, R.J.2
  • 21
    • 37549027570 scopus 로고    scopus 로고
    • Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species
    • Koli K., Myllarniemi M., Keski-Oja J., Kinnula V.L. Transforming growth factor-beta activation in the lung: focus on fibrosis and reactive oxygen species. Antioxid Redox Signal 2008, 10:333-342.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 333-342
    • Koli, K.1    Myllarniemi, M.2    Keski-Oja, J.3    Kinnula, V.L.4
  • 22
    • 53849126120 scopus 로고    scopus 로고
    • Interaction of TGF-beta with immune cells in airway disease
    • Moore B., Murphy R.F., Agrawal D.K. Interaction of TGF-beta with immune cells in airway disease. Curr Mol Med 2008, 8:427-436.
    • (2008) Curr Mol Med , vol.8 , pp. 427-436
    • Moore, B.1    Murphy, R.F.2    Agrawal, D.K.3
  • 24
    • 84859179083 scopus 로고    scopus 로고
    • Activation of canonical Wnt signalling is required for TGF-beta-mediated fibrosis
    • Akhmetshina A., Palumbo K., Dees C., Bergmann C., Venalis P., Zerr P., et al. Activation of canonical Wnt signalling is required for TGF-beta-mediated fibrosis. Nat Commun 2012, 3:735.
    • (2012) Nat Commun , vol.3 , pp. 735
    • Akhmetshina, A.1    Palumbo, K.2    Dees, C.3    Bergmann, C.4    Venalis, P.5    Zerr, P.6
  • 25
  • 26
    • 79955738469 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 suppresses the up-regulation of matrix metalloproteinase-2 by lung fibroblasts in response to tumor necrosis factor-alpha
    • Ye H., Cai P.C., Zhou Q., Ma W.L. Transforming growth factor-beta1 suppresses the up-regulation of matrix metalloproteinase-2 by lung fibroblasts in response to tumor necrosis factor-alpha. Wound Repair Regen 2011, 19:392-399.
    • (2011) Wound Repair Regen , vol.19 , pp. 392-399
    • Ye, H.1    Cai, P.C.2    Zhou, Q.3    Ma, W.L.4
  • 27
    • 0024534130 scopus 로고
    • Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit
    • Heino J., Ignotz R.A., Hemler M.E., Crouse C., Massague J. Regulation of cell adhesion receptors by transforming growth factor-beta. Concomitant regulation of integrins that share a common beta 1 subunit. J Biol Chem 1989, 264:380-388.
    • (1989) J Biol Chem , vol.264 , pp. 380-388
    • Heino, J.1    Ignotz, R.A.2    Hemler, M.E.3    Crouse, C.4    Massague, J.5
  • 28
    • 41449112762 scopus 로고    scopus 로고
    • Transforming growth factor beta 1 increases fibronectin deposition through integrin receptor alpha 5 beta 1 on human airway smooth muscle
    • e4
    • Moir L.M., Burgess J.K., Black J.L. Transforming growth factor beta 1 increases fibronectin deposition through integrin receptor alpha 5 beta 1 on human airway smooth muscle. J Allergy Clin Immunol 2008, 121:1034-1039. e4.
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 1034-1039
    • Moir, L.M.1    Burgess, J.K.2    Black, J.L.3
  • 29
    • 73149098919 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling across ages: from distorted lung development to chronic obstructive pulmonary disease
    • Morty R.E., Konigshoff M., Eickelberg O. Transforming growth factor-beta signaling across ages: from distorted lung development to chronic obstructive pulmonary disease. Proc Am Thorac Soc 2009, 6:607-613.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 607-613
    • Morty, R.E.1    Konigshoff, M.2    Eickelberg, O.3
  • 30
    • 33745860364 scopus 로고    scopus 로고
    • Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling
    • Lee C.G., Kang H.R., Homer R.J., Chupp G., Elias J.A. Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling. Proc Am Thorac Soc 2006, 3:418-423.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 418-423
    • Lee, C.G.1    Kang, H.R.2    Homer, R.J.3    Chupp, G.4    Elias, J.A.5
  • 31
    • 0035964954 scopus 로고    scopus 로고
    • Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice
    • Drab M., Verkade P., Elger M., Kasper M., Lohn M., Lauterbach B., et al. Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 2001, 293:2449-2452.
    • (2001) Science , vol.293 , pp. 2449-2452
    • Drab, M.1    Verkade, P.2    Elger, M.3    Kasper, M.4    Lohn, M.5    Lauterbach, B.6
  • 32
    • 41949132172 scopus 로고    scopus 로고
    • Down-regulation of caveolin-1, an inhibitor of transforming growth factor-beta signaling, in acute allergen-induced airway remodeling
    • Le Saux C.J., Teeters K., Miyasato S.K., Hoffmann P.R., Bollt O., Douet V., et al. Down-regulation of caveolin-1, an inhibitor of transforming growth factor-beta signaling, in acute allergen-induced airway remodeling. J Biol Chem 2008, 283:5760-5768.
    • (2008) J Biol Chem , vol.283 , pp. 5760-5768
    • Le Saux, C.J.1    Teeters, K.2    Miyasato, S.K.3    Hoffmann, P.R.4    Bollt, O.5    Douet, V.6
  • 33
    • 33745855449 scopus 로고    scopus 로고
    • Remodeling in asthma and chronic obstructive pulmonary disease
    • Postma D.S., Timens W. Remodeling in asthma and chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006, 3:434-439.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 434-439
    • Postma, D.S.1    Timens, W.2
  • 34
    • 33646736505 scopus 로고    scopus 로고
    • Airway smooth muscle phenotype and function: interactions with current asthma therapies
    • Halayko A.J., Tran T., Ji S.Y., Yamasaki A., Gosens R. Airway smooth muscle phenotype and function: interactions with current asthma therapies. Curr Drug Targets 2006, 7:525-540.
    • (2006) Curr Drug Targets , vol.7 , pp. 525-540
    • Halayko, A.J.1    Tran, T.2    Ji, S.Y.3    Yamasaki, A.4    Gosens, R.5
  • 35
    • 34147214101 scopus 로고    scopus 로고
    • Expression and activation of TGF-beta isoforms in acute allergen-induced remodelling in asthma
    • Torrego A., Hew M., Oates T., Sukkar M., Fan Chung K. Expression and activation of TGF-beta isoforms in acute allergen-induced remodelling in asthma. Thorax 2007, 62:307-313.
    • (2007) Thorax , vol.62 , pp. 307-313
    • Torrego, A.1    Hew, M.2    Oates, T.3    Sukkar, M.4    Fan Chung, K.5
  • 36
    • 77950393215 scopus 로고    scopus 로고
    • TGF-beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma
    • Bottoms S.E., Howell J.E., Reinhardt A.K., Evans I.C., McAnulty R.J. TGF-beta isoform specific regulation of airway inflammation and remodelling in a murine model of asthma. PLoS One 2010, 5:e9674.
    • (2010) PLoS One , vol.5
    • Bottoms, S.E.1    Howell, J.E.2    Reinhardt, A.K.3    Evans, I.C.4    McAnulty, R.J.5
  • 37
    • 0032431874 scopus 로고    scopus 로고
    • Co-localization of immunoreactive transforming growth factor-beta 1 and decorin in bronchial biopsies from asthmatic and normal subjects
    • Redington A.E., Roche W.R., Holgate S.T., Howarth P.H. Co-localization of immunoreactive transforming growth factor-beta 1 and decorin in bronchial biopsies from asthmatic and normal subjects. J Pathol 1998, 186:410-415.
    • (1998) J Pathol , vol.186 , pp. 410-415
    • Redington, A.E.1    Roche, W.R.2    Holgate, S.T.3    Howarth, P.H.4
  • 41
    • 77955923479 scopus 로고    scopus 로고
    • Gene-gene interaction in regulatory T-cell function in atopy and asthma development in childhood
    • 46 e1-10
    • Bottema R.W., Kerkhof M., Reijmerink N.E., Thijs C., Smit H.A., van Schayck C.P., et al. Gene-gene interaction in regulatory T-cell function in atopy and asthma development in childhood. J Allergy Clin Immunol 2010, 126:338-346. 46 e1-10.
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 338-346
    • Bottema, R.W.1    Kerkhof, M.2    Reijmerink, N.E.3    Thijs, C.4    Smit, H.A.5    van Schayck, C.P.6
  • 42
    • 77951731618 scopus 로고    scopus 로고
    • Polymorphisms in the transforming growth factor-beta1 gene and the risk of asthma: a meta-analysis
    • Zhang Y., Zhang J., Huang J., Li X., He C., Tian C., et al. Polymorphisms in the transforming growth factor-beta1 gene and the risk of asthma: a meta-analysis. Respirology 2010, 15:643-650.
    • (2010) Respirology , vol.15 , pp. 643-650
    • Zhang, Y.1    Zhang, J.2    Huang, J.3    Li, X.4    He, C.5    Tian, C.6
  • 44
    • 0141792277 scopus 로고    scopus 로고
    • Mechanisms of inflammation-mediated airway smooth muscle plasticity and airways remodeling in asthma
    • Halayko A.J., Amrani Y. Mechanisms of inflammation-mediated airway smooth muscle plasticity and airways remodeling in asthma. Respir Physiol Neurobiol 2003, 137:209-222.
    • (2003) Respir Physiol Neurobiol , vol.137 , pp. 209-222
    • Halayko, A.J.1    Amrani, Y.2
  • 45
    • 0033800079 scopus 로고    scopus 로고
    • The bronchial epithelial origins of asthma
    • Holgate S.T. The bronchial epithelial origins of asthma. Chem Immunol 2000, 78:62-71.
    • (2000) Chem Immunol , vol.78 , pp. 62-71
    • Holgate, S.T.1
  • 47
    • 0034995813 scopus 로고    scopus 로고
    • Gene expression of vascular endothelial growth factor and its receptors and angiogenesis in bronchial asthma
    • Hoshino M., Nakamura Y., Hamid Q.A. Gene expression of vascular endothelial growth factor and its receptors and angiogenesis in bronchial asthma. J Allergy Clin Immunol 2001, 107:1034-1038.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 1034-1038
    • Hoshino, M.1    Nakamura, Y.2    Hamid, Q.A.3
  • 48
    • 2342523999 scopus 로고    scopus 로고
    • Airway mucus hypersecretion in asthma: an undervalued pathology?
    • Rogers D.F. Airway mucus hypersecretion in asthma: an undervalued pathology?. Curr Opin Pharmacol 2004, 4:241-250.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 241-250
    • Rogers, D.F.1
  • 49
    • 67650689569 scopus 로고    scopus 로고
    • Asthmatic bronchial fibroblasts demonstrate enhanced potential to differentiate into myofibroblasts in culture
    • Michalik M., Pierzchalska M., Legutko A., Ura M., Ostaszewska A., Soja J., et al. Asthmatic bronchial fibroblasts demonstrate enhanced potential to differentiate into myofibroblasts in culture. Med Sci Monit 2009, 15:BR194-BR201.
    • (2009) Med Sci Monit , vol.15
    • Michalik, M.1    Pierzchalska, M.2    Legutko, A.3    Ura, M.4    Ostaszewska, A.5    Soja, J.6
  • 50
    • 77954489481 scopus 로고    scopus 로고
    • Smoking-related small airway disease-a review and update
    • Beasley M.B. Smoking-related small airway disease-a review and update. Adv Anat Pathol 2010, 17:270-276.
    • (2010) Adv Anat Pathol , vol.17 , pp. 270-276
    • Beasley, M.B.1
  • 51
    • 33845473487 scopus 로고    scopus 로고
    • Cigarette smoke drives small airway remodeling by induction of growth factors in the airway wall
    • Churg A., Tai H., Coulthard T., Wang R., Wright J.L. Cigarette smoke drives small airway remodeling by induction of growth factors in the airway wall. Am J Respir Crit Care Med 2006, 174:1327-1334.
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 1327-1334
    • Churg, A.1    Tai, H.2    Coulthard, T.3    Wang, R.4    Wright, J.L.5
  • 53
    • 80055008094 scopus 로고    scopus 로고
    • Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
    • Soler Artigas M., Loth D.W., Wain L.V., Gharib S.A., Obeidat M., Tang W., et al. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 2011, 43:1082-1090.
    • (2011) Nat Genet , vol.43 , pp. 1082-1090
    • Soler Artigas, M.1    Loth, D.W.2    Wain, L.V.3    Gharib, S.A.4    Obeidat, M.5    Tang, W.6
  • 54
    • 17044453955 scopus 로고    scopus 로고
    • Increased expression of transforming growth factor-beta1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (copd)
    • Takizawa H., Tanaka M., Takami K., Ohtoshi T., Ito K., Satoh M., et al. Increased expression of transforming growth factor-beta1 in small airway epithelium from tobacco smokers and patients with chronic obstructive pulmonary disease (copd). Am J Respir Crit Care Med 2001, 163:1476-1483.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 1476-1483
    • Takizawa, H.1    Tanaka, M.2    Takami, K.3    Ohtoshi, T.4    Ito, K.5    Satoh, M.6
  • 55
    • 0032416948 scopus 로고    scopus 로고
    • Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease
    • de Boer W.I., van Schadewijk A., Sont J.K., Sharma H.S., Stolk J., Hiemstra P.S., et al. Transforming growth factor beta1 and recruitment of macrophages and mast cells in airways in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998, 158:1951-1957.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1951-1957
    • de Boer, W.I.1    van Schadewijk, A.2    Sont, J.K.3    Sharma, H.S.4    Stolk, J.5    Hiemstra, P.S.6
  • 56
    • 60549097786 scopus 로고    scopus 로고
    • Smad gene expression in pulmonary fibroblasts: indications for defective Ecm repair in Copd
    • Zandvoort A., Postma D.S., Jonker M.R., Noordhoek J.A., Vos J.T., Timens W. Smad gene expression in pulmonary fibroblasts: indications for defective Ecm repair in Copd. Resp Res 2008, 9:83.
    • (2008) Resp Res , vol.9 , pp. 83
    • Zandvoort, A.1    Postma, D.S.2    Jonker, M.R.3    Noordhoek, J.A.4    Vos, J.T.5    Timens, W.6
  • 57
  • 61
    • 4344653389 scopus 로고    scopus 로고
    • Smad-signaling in chronic obstructive pulmonary disease: transcriptional down-regulation of inhibitory Smad 6 and 7 by cigarette smoke
    • Springer J., Scholz F.R., Peiser C., Groneberg D.A., Fischer A. Smad-signaling in chronic obstructive pulmonary disease: transcriptional down-regulation of inhibitory Smad 6 and 7 by cigarette smoke. Biol Chem 2004, 385:649-653.
    • (2004) Biol Chem , vol.385 , pp. 649-653
    • Springer, J.1    Scholz, F.R.2    Peiser, C.3    Groneberg, D.A.4    Fischer, A.5
  • 62
    • 15444372825 scopus 로고    scopus 로고
    • Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-Kinase
    • Yi J.Y., Shin I., Arteaga C.L. Type I transforming growth factor beta receptor binds to and activates phosphatidylinositol 3-Kinase. J Biol Chem 2005, 280:10870-10876.
    • (2005) J Biol Chem , vol.280 , pp. 10870-10876
    • Yi, J.Y.1    Shin, I.2    Arteaga, C.L.3
  • 64
    • 48749118638 scopus 로고    scopus 로고
    • Dual Erk and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: differences in asthma
    • Burgess J.K., Lee J.H., Ge Q., Ramsay E.E., Poniris M.H., Parmentier J., et al. Dual Erk and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: differences in asthma. J Cell Physiol 2008, 216:673-679.
    • (2008) J Cell Physiol , vol.216 , pp. 673-679
    • Burgess, J.K.1    Lee, J.H.2    Ge, Q.3    Ramsay, E.E.4    Poniris, M.H.5    Parmentier, J.6
  • 66
    • 77950556544 scopus 로고    scopus 로고
    • Cooperation of Tlr2 with Myd88, Pi3k, and Rac1 in lipoteichoic acid-induced Cpla2/Cox-2-dependent airway inflammatory responses
    • Lee I.T., Lee C.W., Tung W.H., Wang S.W., Lin C.C., Shu J.C., et al. Cooperation of Tlr2 with Myd88, Pi3k, and Rac1 in lipoteichoic acid-induced Cpla2/Cox-2-dependent airway inflammatory responses. Am J Pathol 2010, 176:1671-1684.
    • (2010) Am J Pathol , vol.176 , pp. 1671-1684
    • Lee, I.T.1    Lee, C.W.2    Tung, W.H.3    Wang, S.W.4    Lin, C.C.5    Shu, J.C.6
  • 67
    • 79955762960 scopus 로고    scopus 로고
    • Akt activation induces hypertrophy without contractile phenotypic maturation in airway smooth muscle
    • Ma L., Brown M., Kogut P., Serban K., Li X., McConville J., et al. Akt activation induces hypertrophy without contractile phenotypic maturation in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2011, 300:L701-L709.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.300
    • Ma, L.1    Brown, M.2    Kogut, P.3    Serban, K.4    Li, X.5    McConville, J.6
  • 69
    • 17144386566 scopus 로고    scopus 로고
    • Systematic evaluation of anti-apoptotic growth factor signaling in vascular smooth muscle cells. Only phosphatidylinositol 3'-kinase is important
    • Vantler M., Caglayan E., Zimmermann W.H., Baumer A.T., Rosenkranz S. Systematic evaluation of anti-apoptotic growth factor signaling in vascular smooth muscle cells. Only phosphatidylinositol 3'-kinase is important. J Biol Chem 2005, 280:14168-14176.
    • (2005) J Biol Chem , vol.280 , pp. 14168-14176
    • Vantler, M.1    Caglayan, E.2    Zimmermann, W.H.3    Baumer, A.T.4    Rosenkranz, S.5
  • 70
    • 0032810950 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation
    • Krymskaya V.P., Penn R.B., Orsini M.J., Scott P.H., Plevin R.J., Walker T.R., et al. Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation. Am J Physiol 1999, 277:L65-L78.
    • (1999) Am J Physiol , vol.277
    • Krymskaya, V.P.1    Penn, R.B.2    Orsini, M.J.3    Scott, P.H.4    Plevin, R.J.5    Walker, T.R.6
  • 71
    • 79955015620 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase isoform-specific effects in airway mesenchymal cell function
    • Moir L.M., Trian T., Ge Q., Shepherd P.R., Burgess J.K., Oliver B.G., et al. Phosphatidylinositol 3-kinase isoform-specific effects in airway mesenchymal cell function. J Pharmacol Exp Ther 2011, 337:557-566.
    • (2011) J Pharmacol Exp Ther , vol.337 , pp. 557-566
    • Moir, L.M.1    Trian, T.2    Ge, Q.3    Shepherd, P.R.4    Burgess, J.K.5    Oliver, B.G.6
  • 72
    • 33947358942 scopus 로고    scopus 로고
    • Therapeutic potential of phosphatidylinositol 3-Kinase inhibitors in inflammatory respiratory disease
    • Ito K., Caramori G., Adcock I.M. Therapeutic potential of phosphatidylinositol 3-Kinase inhibitors in inflammatory respiratory disease. J Pharmacol Exp Ther 2007, 321:1-8.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 1-8
    • Ito, K.1    Caramori, G.2    Adcock, I.M.3
  • 73
    • 42449116645 scopus 로고    scopus 로고
    • Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-Kinase P110delta-dependent mechanism
    • Farghaly H.S., Blagbrough I.S., Medina-Tato D.A., Watson M.L. Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-Kinase P110delta-dependent mechanism. Mol Pharmacol 2008, 73:1530-1537.
    • (2008) Mol Pharmacol , vol.73 , pp. 1530-1537
    • Farghaly, H.S.1    Blagbrough, I.S.2    Medina-Tato, D.A.3    Watson, M.L.4
  • 75
    • 4444302962 scopus 로고    scopus 로고
    • Phophatidylinositol-3 kinase/mammalian target of rapamycin/P70s6k regulates contractile protein accumulation in airway myocyte differentiation
    • Halayko A.J., Kartha S., Stelmack G.L., McConville J., Tam J., Camoretti-Mercado B., et al. Phophatidylinositol-3 kinase/mammalian target of rapamycin/P70s6k regulates contractile protein accumulation in airway myocyte differentiation. Am J Respir Cell Mol Biol 2004, 31:266-275.
    • (2004) Am J Respir Cell Mol Biol , vol.31 , pp. 266-275
    • Halayko, A.J.1    Kartha, S.2    Stelmack, G.L.3    McConville, J.4    Tam, J.5    Camoretti-Mercado, B.6
  • 79
    • 63849216835 scopus 로고    scopus 로고
    • TGF-beta effects on airway smooth muscle cell proliferation, Vegf release and signal transduction pathways
    • Shin J.H., Shim J.W., Kim D.S., Shim J.Y. TGF-beta effects on airway smooth muscle cell proliferation, Vegf release and signal transduction pathways. Respirology 2009, 14:347-353.
    • (2009) Respirology , vol.14 , pp. 347-353
    • Shin, J.H.1    Shim, J.W.2    Kim, D.S.3    Shim, J.Y.4
  • 80
    • 0024505353 scopus 로고
    • Subepithelial fibrosis in the bronchi of asthmatics
    • Roche W.R., Beasley R., Williams J.H., Holgate S.T. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1989, 1:520-524.
    • (1989) Lancet , vol.1 , pp. 520-524
    • Roche, W.R.1    Beasley, R.2    Williams, J.H.3    Holgate, S.T.4
  • 84
    • 0033574429 scopus 로고    scopus 로고
    • Proliferative defect and embryonic lethality in mice homozygous for a deletion in the P110α subunit of phosphoinositide 3-kinase
    • Bi L., Okabe I., Bernard D.J., Wynshaw-Boris A., Nussbaum R.L. Proliferative defect and embryonic lethality in mice homozygous for a deletion in the P110α subunit of phosphoinositide 3-kinase. J Biol Chem 1999, 274:10963-10968.
    • (1999) J Biol Chem , vol.274 , pp. 10963-10968
    • Bi, L.1    Okabe, I.2    Bernard, D.J.3    Wynshaw-Boris, A.4    Nussbaum, R.L.5
  • 85
    • 33645827963 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model
    • Lee K.S., Lee H.K., Hayflick J.S., Lee Y.C., Puri K.D. Inhibition of phosphoinositide 3-kinase delta attenuates allergic airway inflammation and hyperresponsiveness in murine asthma model. FASEB J 2006, 20:455-465.
    • (2006) FASEB J , vol.20 , pp. 455-465
    • Lee, K.S.1    Lee, H.K.2    Hayflick, J.S.3    Lee, Y.C.4    Puri, K.D.5
  • 86
    • 19644373254 scopus 로고    scopus 로고
    • Wnt signaling in disease and in development
    • Nusse R. Wnt signaling in disease and in development. Cell Res 2005, 15:28-32.
    • (2005) Cell Res , vol.15 , pp. 28-32
    • Nusse, R.1
  • 87
    • 80054777961 scopus 로고    scopus 로고
    • New insights into the mechanism of Wnt signaling pathway activation
    • Kikuchi A., Yamamoto H., Sato A., Matsumoto S. New insights into the mechanism of Wnt signaling pathway activation. Int Rev Cell Mol Biol 2011, 291:21-71.
    • (2011) Int Rev Cell Mol Biol , vol.291 , pp. 21-71
    • Kikuchi, A.1    Yamamoto, H.2    Sato, A.3    Matsumoto, S.4
  • 88
    • 80053467945 scopus 로고    scopus 로고
    • A Wnter revisit: new faces of beta-catenin and Tcfs in pluripotency
    • Watanabe K., Dai X. A Wnter revisit: new faces of beta-catenin and Tcfs in pluripotency. Sci Signal 2011, 4:pe41.
    • (2011) Sci Signal , vol.4
    • Watanabe, K.1    Dai, X.2
  • 89
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan C.Y., Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004, 20:781-810.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 90
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S., Moon R.T. Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 2009, 10:468-477.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 91
    • 0036904895 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian transforming growth factor-beta superfamily
    • Chang H., Brown C.W., Matzuk M.M. Genetic analysis of the mammalian transforming growth factor-beta superfamily. Endocr Rev 2002, 23:787-823.
    • (2002) Endocr Rev , vol.23 , pp. 787-823
    • Chang, H.1    Brown, C.W.2    Matzuk, M.M.3
  • 92
    • 0034677494 scopus 로고    scopus 로고
    • Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer
    • Nishita M., Hashimoto M.K., Ogata S., Laurent M.N., Ueno N., Shibuya H., et al. Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer. Nature 2000, 403:781-785.
    • (2000) Nature , vol.403 , pp. 781-785
    • Nishita, M.1    Hashimoto, M.K.2    Ogata, S.3    Laurent, M.N.4    Ueno, N.5    Shibuya, H.6
  • 93
    • 0034682515 scopus 로고    scopus 로고
    • Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and Wnt pathways
    • Labbe E., Letamendia A., Attisano L. Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and Wnt pathways. Proc Natl Acad Sci U S A 2000, 97:8358-8363.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8358-8363
    • Labbe, E.1    Letamendia, A.2    Attisano, L.3
  • 94
    • 58149100136 scopus 로고    scopus 로고
    • Novel regulation of vascular endothelial growth factor-a (Vegf-a) by Transforming growth factor (Beta)1: requirement for Smads, (beta)-catenin, and Gsk3(beta)
    • Clifford R.L., Deacon K., Knox A.J. Novel regulation of vascular endothelial growth factor-a (Vegf-a) by Transforming growth factor (Beta)1: requirement for Smads, (beta)-catenin, and Gsk3(beta). J Biol Chem 2008, 283:35337-35353.
    • (2008) J Biol Chem , vol.283 , pp. 35337-35353
    • Clifford, R.L.1    Deacon, K.2    Knox, A.J.3
  • 95
    • 5644261271 scopus 로고    scopus 로고
    • The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways
    • Lei S., Dubeykovskiy A., Chakladar A., Wojtukiewicz L., Wang T.C. The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways. J Biol Chem 2004, 279:42492-42502.
    • (2004) J Biol Chem , vol.279 , pp. 42492-42502
    • Lei, S.1    Dubeykovskiy, A.2    Chakladar, A.3    Wojtukiewicz, L.4    Wang, T.C.5
  • 96
    • 0347722250 scopus 로고    scopus 로고
    • Growth factors regulate beta-catenin-mediated Tcf-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing
    • Cheon S.S., Nadesan P., Poon R., Alman B.A. Growth factors regulate beta-catenin-mediated Tcf-dependent transcriptional activation in fibroblasts during the proliferative phase of wound healing. Exp Cell Res 2004, 293:267-274.
    • (2004) Exp Cell Res , vol.293 , pp. 267-274
    • Cheon, S.S.1    Nadesan, P.2    Poon, R.3    Alman, B.A.4
  • 97
    • 80053615345 scopus 로고    scopus 로고
    • Activation of Wnt/beta-catenin signaling in pulmonary fibroblasts by TGF-beta is increased in chronic obstructive pulmonary disease
    • Baarsma H.A., Spanjer A.I., Haitsma G., Engelbertink L.H., Meurs H., Jonker M.R., et al. Activation of Wnt/beta-catenin signaling in pulmonary fibroblasts by TGF-beta is increased in chronic obstructive pulmonary disease. PLoS One 2011, 6:e25450.
    • (2011) PLoS One , vol.6
    • Baarsma, H.A.1    Spanjer, A.I.2    Haitsma, G.3    Engelbertink, L.H.4    Meurs, H.5    Jonker, M.R.6
  • 98
    • 77952316612 scopus 로고    scopus 로고
    • De novo synthesis of {beta}-catenin via H-Ras and Mek regulates airway smooth muscle growth
    • Gosens R., Baarsma H.A., Heijink I.H., Oenema T.A., Halayko A.J., Meurs H., et al. De novo synthesis of {beta}-catenin via H-Ras and Mek regulates airway smooth muscle growth. FASEB J 2010, 24:757-768.
    • (2010) FASEB J , vol.24 , pp. 757-768
    • Gosens, R.1    Baarsma, H.A.2    Heijink, I.H.3    Oenema, T.A.4    Halayko, A.J.5    Meurs, H.6
  • 99
    • 77950553992 scopus 로고    scopus 로고
    • Smad3 prevents beta-catenin degradation and facilitates beta-catenin nuclear translocation in chondrocytes
    • Zhang M., Wang M., Tan X., Li T.F., Zhang Y.E., Chen D. Smad3 prevents beta-catenin degradation and facilitates beta-catenin nuclear translocation in chondrocytes. J Biol Chem 2010, 285:8703-8710.
    • (2010) J Biol Chem , vol.285 , pp. 8703-8710
    • Zhang, M.1    Wang, M.2    Tan, X.3    Li, T.F.4    Zhang, Y.E.5    Chen, D.6
  • 100
    • 79956200232 scopus 로고    scopus 로고
    • Wnt3a induces myofibroblast differentiation by upregulating TGF-beta signaling through Smad2 in a beta-catenin-dependent manner
    • Carthy J.M., Garmaroudi F.S., Luo Z., McManus B.M. Wnt3a induces myofibroblast differentiation by upregulating TGF-beta signaling through Smad2 in a beta-catenin-dependent manner. PLoS One 2011, 6:e19809.
    • (2011) PLoS One , vol.6
    • Carthy, J.M.1    Garmaroudi, F.S.2    Luo, Z.3    McManus, B.M.4
  • 101
    • 84857393123 scopus 로고    scopus 로고
    • Autocrine Wnt5a signaling is increased in asthma and regulates TGF-beta1 induced Ecm production by airway smooth muscle cells
    • Kumawat K., Bos S., Borger P., Tamm M., Postma D.S., Koppelman G.H., et al. Autocrine Wnt5a signaling is increased in asthma and regulates TGF-beta1 induced Ecm production by airway smooth muscle cells. Am J Respir Crit Care Med 2011, 183.
    • (2011) Am J Respir Crit Care Med , pp. 183
    • Kumawat, K.1    Bos, S.2    Borger, P.3    Tamm, M.4    Postma, D.S.5    Koppelman, G.H.6
  • 102
    • 47149084693 scopus 로고    scopus 로고
    • The Gsk-3/beta-catenin-signalling axis in smooth muscle and its relationship with remodelling
    • Gosens R., Meurs H., Schmidt M. The Gsk-3/beta-catenin-signalling axis in smooth muscle and its relationship with remodelling. Naunyn Schmiedebergs Arch Pharmacol 2008, 378:185-191.
    • (2008) Naunyn Schmiedebergs Arch Pharmacol , vol.378 , pp. 185-191
    • Gosens, R.1    Meurs, H.2    Schmidt, M.3
  • 103
    • 74849084373 scopus 로고    scopus 로고
    • Airway structural components drive airway smooth muscle remodeling in asthma
    • Dekkers B.G., Maarsingh H., Meurs H., Gosens R. Airway structural components drive airway smooth muscle remodeling in asthma. Proc Am Thorac Soc 2009, 6:683-692.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 683-692
    • Dekkers, B.G.1    Maarsingh, H.2    Meurs, H.3    Gosens, R.4
  • 104
    • 44349190984 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3beta is sufficient for airway smooth muscle hypertrophy
    • Deng H., Dokshin G.A., Lei J., Goldsmith A.M., Bitar K.N., Fingar D.C., et al. Inhibition of glycogen synthase kinase-3beta is sufficient for airway smooth muscle hypertrophy. J Biol Chem 2008, 283:10198-10207.
    • (2008) J Biol Chem , vol.283 , pp. 10198-10207
    • Deng, H.1    Dokshin, G.A.2    Lei, J.3    Goldsmith, A.M.4    Bitar, K.N.5    Fingar, D.C.6
  • 108
    • 77953642639 scopus 로고    scopus 로고
    • Phosphate and calcium are required for TGFbeta-mediated stimulation of Ank expression and function during chondrogenesis
    • Oca P., Zaka R., Dion A.S., Freeman T.A., Williams C.J. Phosphate and calcium are required for TGFbeta-mediated stimulation of Ank expression and function during chondrogenesis. J Cell Physiol 2010, 224:540-548.
    • (2010) J Cell Physiol , vol.224 , pp. 540-548
    • Oca, P.1    Zaka, R.2    Dion, A.S.3    Freeman, T.A.4    Williams, C.J.5
  • 111
    • 0032580202 scopus 로고    scopus 로고
    • Calcium oscillations increase the efficiency and specificity of gene expression
    • Dolmetsch R.E., Xu K., Lewis R.S. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 1998, 392:933-936.
    • (1998) Nature , vol.392 , pp. 933-936
    • Dolmetsch, R.E.1    Xu, K.2    Lewis, R.S.3
  • 113
    • 70350328041 scopus 로고    scopus 로고
    • Atp stimulates Ca(2+)-waves and gene expression in cultured human pulmonary fibroblasts
    • Janssen L.J., Farkas L., Rahman T., Kolb M.R. Atp stimulates Ca(2+)-waves and gene expression in cultured human pulmonary fibroblasts. Int J Biochem Cell Biol 2009, 41:2477-2484.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 2477-2484
    • Janssen, L.J.1    Farkas, L.2    Rahman, T.3    Kolb, M.R.4
  • 114
    • 0029112651 scopus 로고
    • Increased expression of messenger Rna for collagen type I, collagen type Iii, and fibronectin in myometrium of pregnancy
    • Stewart E.A., Floor A.E., Jain P., Nowak R.A. Increased expression of messenger Rna for collagen type I, collagen type Iii, and fibronectin in myometrium of pregnancy. Obstet Gynecol 1995, 86:417-422.
    • (1995) Obstet Gynecol , vol.86 , pp. 417-422
    • Stewart, E.A.1    Floor, A.E.2    Jain, P.3    Nowak, R.A.4
  • 115
    • 0023631004 scopus 로고
    • Transforming growth factor beta (TGF beta) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin Mrnas in normal human dermal fibroblasts
    • Varga J., Rosenbloom J., Jimenez S.A. Transforming growth factor beta (TGF beta) causes a persistent increase in steady-state amounts of type I and type III collagen and fibronectin Mrnas in normal human dermal fibroblasts. Biochem J 1987, 247:597-604.
    • (1987) Biochem J , vol.247 , pp. 597-604
    • Varga, J.1    Rosenbloom, J.2    Jimenez, S.A.3
  • 116
    • 0343292988 scopus 로고
    • Transforming growth factor beta increases Mrna for matrix proteins both in the presence and in the absence of changes in Mrna stability
    • Penttinen R.P., Kobayashi S., Bornstein P. Transforming growth factor beta increases Mrna for matrix proteins both in the presence and in the absence of changes in Mrna stability. Proc Natl Acad Sci U S A 1988, 85:1105-1108.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 1105-1108
    • Penttinen, R.P.1    Kobayashi, S.2    Bornstein, P.3
  • 117
  • 118
    • 0036025218 scopus 로고    scopus 로고
    • TGF-Beta1 calcium signaling increases alpha5 integrin expression in osteoblasts
    • Nesti L.J., Caterson E.J., Wang M., Chang R., Chapovsky F., Hoek J.B., et al. TGF-Beta1 calcium signaling increases alpha5 integrin expression in osteoblasts. J Orthop Res 2002, 20:1042-1049.
    • (2002) J Orthop Res , vol.20 , pp. 1042-1049
    • Nesti, L.J.1    Caterson, E.J.2    Wang, M.3    Chang, R.4    Chapovsky, F.5    Hoek, J.B.6
  • 119
    • 70449085204 scopus 로고    scopus 로고
    • S100a8/A9: a mediator of severe asthma pathogenesis and morbidity?
    • Halayko A.J., Ghavami S. S100a8/A9: a mediator of severe asthma pathogenesis and morbidity?. Can J Physiol Pharmacol 2009, 87:743-755.
    • (2009) Can J Physiol Pharmacol , vol.87 , pp. 743-755
    • Halayko, A.J.1    Ghavami, S.2
  • 120
    • 0026659883 scopus 로고
    • Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
    • Neeper M., Schmidt A.M., Brett J., Yan S.D., Wang F., Pan Y.C., et al. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. J Biol Chem 1992, 267:14998-15004.
    • (1992) J Biol Chem , vol.267 , pp. 14998-15004
    • Neeper, M.1    Schmidt, A.M.2    Brett, J.3    Yan, S.D.4    Wang, F.5    Pan, Y.C.6
  • 121
    • 1242290096 scopus 로고    scopus 로고
    • Receptor for age (RAGE) is a gene within the major histocompatibility class III region: implications for host response mechanisms in homeostasis and chronic disease
    • Schmidt A.M., Stern D.M. Receptor for age (RAGE) is a gene within the major histocompatibility class III region: implications for host response mechanisms in homeostasis and chronic disease. Front Biosci 2001, 6:D1151-D1160.
    • (2001) Front Biosci , vol.6
    • Schmidt, A.M.1    Stern, D.M.2
  • 122
    • 0034695098 scopus 로고    scopus 로고
    • The biology of the receptor for advanced glycation end products and its ligands
    • Schmidt A.M., Yan S.D., Yan S.F., Stern D.M. The biology of the receptor for advanced glycation end products and its ligands. Biochim Biophys Acta 2000, 1498:99-111.
    • (2000) Biochim Biophys Acta , vol.1498 , pp. 99-111
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 123
    • 35348927441 scopus 로고    scopus 로고
    • Kinetics, role and therapeutic implications of endogenous soluble form of receptor for advanced glycation end products (sRAGE) in diabetes
    • Yamagishi S., Matsui T., Nakamura K. Kinetics, role and therapeutic implications of endogenous soluble form of receptor for advanced glycation end products (sRAGE) in diabetes. Curr Drug Targets 2007, 8:1138-1143.
    • (2007) Curr Drug Targets , vol.8 , pp. 1138-1143
    • Yamagishi, S.1    Matsui, T.2    Nakamura, K.3
  • 125
    • 0033603241 scopus 로고    scopus 로고
    • RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides
    • Hofmann M.A., Drury S., Fu C., Qu W., Taguchi A., Lu Y., et al. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell. 1999, 97:889-901.
    • (1999) Cell. , vol.97 , pp. 889-901
    • Hofmann, M.A.1    Drury, S.2    Fu, C.3    Qu, W.4    Taguchi, A.5    Lu, Y.6
  • 126
    • 1642336325 scopus 로고    scopus 로고
    • Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-Erk1/2 map kinase signaling pathway
    • Li J.H., Wang W., Huang X.R., Oldfield M., Schmidt A.M., Cooper M.E., et al. Advanced glycation end products induce tubular epithelial-myofibroblast transition through the RAGE-Erk1/2 map kinase signaling pathway. Am J Pathol 2004, 164:1389-1397.
    • (2004) Am J Pathol , vol.164 , pp. 1389-1397
    • Li, J.H.1    Wang, W.2    Huang, X.R.3    Oldfield, M.4    Schmidt, A.M.5    Cooper, M.E.6
  • 127
    • 0035661067 scopus 로고    scopus 로고
    • Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)
    • Oldfield M.D., Bach L.A., Forbes J.M., Nikolic-Paterson D., McRobert A., Thallas V., et al. Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE). J Clin Invest 2001, 108:1853-1863.
    • (2001) J Clin Invest , vol.108 , pp. 1853-1863
    • Oldfield, M.D.1    Bach, L.A.2    Forbes, J.M.3    Nikolic-Paterson, D.4    McRobert, A.5    Thallas, V.6
  • 128
    • 0027718105 scopus 로고
    • Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues
    • Brett J., Schmidt A.M., Yan S.D., Zou Y.S., Weidman E., Pinsky D., et al. Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues. Am J Pathol 1993, 143:1699-1712.
    • (1993) Am J Pathol , vol.143 , pp. 1699-1712
    • Brett, J.1    Schmidt, A.M.2    Yan, S.D.3    Zou, Y.S.4    Weidman, E.5    Pinsky, D.6
  • 130
    • 40449092262 scopus 로고    scopus 로고
    • A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosis
    • Englert J.M., Hanford L.E., Kaminski N., Tobolewski J.M., Tan R.J., Fattman C.L., et al. A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosis. Am J Pathol 2008, 172:583-591.
    • (2008) Am J Pathol , vol.172 , pp. 583-591
    • Englert, J.M.1    Hanford, L.E.2    Kaminski, N.3    Tobolewski, J.M.4    Tan, R.J.5    Fattman, C.L.6
  • 131
    • 33646243227 scopus 로고    scopus 로고
    • Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury
    • Uchida T., Shirasawa M., Ware L.B., Kojima K., Hata Y., Makita K., et al. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med 2006, 173:1008-1015.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 1008-1015
    • Uchida, T.1    Shirasawa, M.2    Ware, L.B.3    Kojima, K.4    Hata, Y.5    Makita, K.6
  • 133
    • 33846027812 scopus 로고    scopus 로고
    • Regulation of calprotectin expression by interleukin-1alpha and transforming growth factor-beta in human gingival keratinocytes
    • Hayashi N., Kido J., Kido R., Wada C., Kataoka M., Shinohara Y., et al. Regulation of calprotectin expression by interleukin-1alpha and transforming growth factor-beta in human gingival keratinocytes. J Periodontal Res 2007, 42:1-7.
    • (2007) J Periodontal Res , vol.42 , pp. 1-7
    • Hayashi, N.1    Kido, J.2    Kido, R.3    Wada, C.4    Kataoka, M.5    Shinohara, Y.6
  • 134
    • 84871709863 scopus 로고    scopus 로고
    • Levels of Hmgb1 in induced sputum from patients with asthma and chronic obstructive pulmonary disease
    • Cheng Z., Kang Y., Wu Q.G., Dai L.L., Song Y.N., Xia J., et al. Levels of Hmgb1 in induced sputum from patients with asthma and chronic obstructive pulmonary disease. Zhonghua Yi Xue Za Zhi 2011, 91:2981-2984.
    • (2011) Zhonghua Yi Xue Za Zhi , vol.91 , pp. 2981-2984
    • Cheng, Z.1    Kang, Y.2    Wu, Q.G.3    Dai, L.L.4    Song, Y.N.5    Xia, J.6
  • 135
    • 79960726338 scopus 로고    scopus 로고
    • High mobility group protein B1 (Hmgb1) in asthma: comparison of patients with chronic obstructive pulmonary disease and healthy controls
    • Hou C., Zhao H., Liu L., Li W., Zhou X., Lv Y., et al. High mobility group protein B1 (Hmgb1) in asthma: comparison of patients with chronic obstructive pulmonary disease and healthy controls. Mol Med 2011, 17:807-815.
    • (2011) Mol Med , vol.17 , pp. 807-815
    • Hou, C.1    Zhao, H.2    Liu, L.3    Li, W.4    Zhou, X.5    Lv, Y.6
  • 136
    • 79952282593 scopus 로고    scopus 로고
    • Increased levels of Hmgb-1 and endogenous secretory RAGE in induced sputum from asthmatic patients
    • Watanabe T., Asai K., Fujimoto H., Tanaka H., Kanazawa H., Hirata K. Increased levels of Hmgb-1 and endogenous secretory RAGE in induced sputum from asthmatic patients. Respir Med 2011, 105:519-525.
    • (2011) Respir Med , vol.105 , pp. 519-525
    • Watanabe, T.1    Asai, K.2    Fujimoto, H.3    Tanaka, H.4    Kanazawa, H.5    Hirata, K.6
  • 139
    • 9144241208 scopus 로고    scopus 로고
    • Reversing established sepsis with antagonists of endogenous high-mobility group box 1
    • Yang H., Ochani M., Li J., Qiang X., Tanovic M., Harris H.E., et al. Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proc Natl Acad Sci U S A 2004, 101:296-301.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 296-301
    • Yang, H.1    Ochani, M.2    Li, J.3    Qiang, X.4    Tanovic, M.5    Harris, H.E.6
  • 140
    • 77952307233 scopus 로고    scopus 로고
    • Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease
    • Ferhani N., Letuve S., Kozhich A., Thibaudeau O., Grandsaigne M., Maret M., et al. Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2010, 181:917-927.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 917-927
    • Ferhani, N.1    Letuve, S.2    Kozhich, A.3    Thibaudeau, O.4    Grandsaigne, M.5    Maret, M.6
  • 143
    • 80052089457 scopus 로고    scopus 로고
    • Expression of pro-inflammatory protein S100a12 (En-RAGE) in Behcet's disease and its association with disease activity: a pilot study
    • Han E.C., Cho S.B., Ahn K.J., Oh S.H., Kim J., Kim D.S., et al. Expression of pro-inflammatory protein S100a12 (En-RAGE) in Behcet's disease and its association with disease activity: a pilot study. Ann Dermatol 2011, 23:313-320.
    • (2011) Ann Dermatol , vol.23 , pp. 313-320
    • Han, E.C.1    Cho, S.B.2    Ahn, K.J.3    Oh, S.H.4    Kim, J.5    Kim, D.S.6
  • 144
    • 0242441020 scopus 로고    scopus 로고
    • Expression of the pro-inflammatory protein S100a12 (En-RAGE) in rheumatoid and psoriatic arthritis
    • Foell D., Kane D., Bresnihan B., Vogl T., Nacken W., Sorg C., et al. Expression of the pro-inflammatory protein S100a12 (En-RAGE) in rheumatoid and psoriatic arthritis. Rheumatology (Oxford) 2003, 42:1383-1389.
    • (2003) Rheumatology (Oxford) , vol.42 , pp. 1383-1389
    • Foell, D.1    Kane, D.2    Bresnihan, B.3    Vogl, T.4    Nacken, W.5    Sorg, C.6
  • 145
    • 79955760681 scopus 로고    scopus 로고
    • Transgenic expression of human S100a12 induces structural airway abnormalities and limited lung inflammation in a mouse model of allergic inflammation
    • Hofmann Bowman M.A., Heydemann A., Gawdzik J., Shilling R.A., Camoretti-Mercado B. Transgenic expression of human S100a12 induces structural airway abnormalities and limited lung inflammation in a mouse model of allergic inflammation. Clin Exp Allergy 2011, 41:878-889.
    • (2011) Clin Exp Allergy , vol.41 , pp. 878-889
    • Hofmann Bowman, M.A.1    Heydemann, A.2    Gawdzik, J.3    Shilling, R.A.4    Camoretti-Mercado, B.5
  • 146
    • 85026274407 scopus 로고    scopus 로고
    • Hofmann Bowman MA. S100a12 and the airway smooth muscle: beyond inflammation and constriction
    • S1:007
    • Camoretti-Mercado B., Karrar E., Nunez L. Hofmann Bowman MA. S100a12 and the airway smooth muscle: beyond inflammation and constriction. J Aller Ther 2012, S1:007. 10.4172/2155-6121.S1-007.
    • (2012) J Aller Ther
    • Camoretti-Mercado, B.1    Karrar, E.2    Nunez, L.3
  • 148
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: a double-edged sword
    • Shintani T., Klionsky D.J. Autophagy in health and disease: a double-edged sword. Science 2004, 306:990-995.
    • (2004) Science , vol.306 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 149
    • 14044277429 scopus 로고    scopus 로고
    • The molecular machinery of autophagy: unanswered questions
    • Klionsky D.J. The molecular machinery of autophagy: unanswered questions. J Cell Sci 2005, 118:7-18.
    • (2005) J Cell Sci , vol.118 , pp. 7-18
    • Klionsky, D.J.1
  • 150
    • 4344673498 scopus 로고    scopus 로고
    • Mechanisms of chaperone-mediated autophagy
    • Majeski A.E., Dice J.F. Mechanisms of chaperone-mediated autophagy. Int J Biochem Cell Biol 2004, 36:2435-2444.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2435-2444
    • Majeski, A.E.1    Dice, J.F.2
  • 151
    • 81555219121 scopus 로고    scopus 로고
    • Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development
    • Alavian S.M., Ande S.R., Coombs K.M., Yeganeh B., Davoodpour P., Hashemi M., et al. Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development. J Viral Hepat 2011, 18:821-830.
    • (2011) J Viral Hepat , vol.18 , pp. 821-830
    • Alavian, S.M.1    Ande, S.R.2    Coombs, K.M.3    Yeganeh, B.4    Davoodpour, P.5    Hashemi, M.6
  • 152
    • 26844531363 scopus 로고    scopus 로고
    • Maturation of autophagic vacuoles in mammalian cells
    • Eskelinen E.L. Maturation of autophagic vacuoles in mammalian cells. Autophagy 2005, 1:1-10.
    • (2005) Autophagy , vol.1 , pp. 1-10
    • Eskelinen, E.L.1
  • 154
    • 34250864795 scopus 로고    scopus 로고
    • Protein turnover via autophagy: implications for metabolism
    • Mizushima N., Klionsky D.J. Protein turnover via autophagy: implications for metabolism. Annu Rev Nutr 2007, 27:19-40.
    • (2007) Annu Rev Nutr , vol.27 , pp. 19-40
    • Mizushima, N.1    Klionsky, D.J.2
  • 155
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N., Yamamoto A., Matsui M., Yoshimori T., Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004, 15:1101-1111.
    • (2004) Mol Biol Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamoto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 156
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • Lum J.J., Bauer D.E., Kong M., Harris M.H., Li C., Lindsten T., et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell. 2005, 120:237-248.
    • (2005) Cell. , vol.120 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, C.5    Lindsten, T.6
  • 158
    • 49749120592 scopus 로고    scopus 로고
    • Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells
    • Periyasamy-Thandavan S., Jiang M., Wei Q., Smith R., Yin X.M., Dong Z. Autophagy is cytoprotective during cisplatin injury of renal proximal tubular cells. Kidney Int 2008, 74:631-640.
    • (2008) Kidney Int , vol.74 , pp. 631-640
    • Periyasamy-Thandavan, S.1    Jiang, M.2    Wei, Q.3    Smith, R.4    Yin, X.M.5    Dong, Z.6
  • 159
    • 79551622901 scopus 로고    scopus 로고
    • Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for P53
    • Ghavami S., Mutawe M.M., Sharma P., Yeganeh B., McNeill K.D., Klonisch T., et al. Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for P53. PLoS One 2011, 6:e16523.
    • (2011) PLoS One , vol.6
    • Ghavami, S.1    Mutawe, M.M.2    Sharma, P.3    Yeganeh, B.4    McNeill, K.D.5    Klonisch, T.6
  • 160
    • 78549252103 scopus 로고    scopus 로고
    • TGF-{Beta}1 protects against mesangial cell apoptosis via induction of autophagy
    • Ding Y, Kim JK, Kim SI, Na HJ, Jun SY, Lee SJ, et al. TGF-{Beta}1 protects against mesangial cell apoptosis via induction of autophagy. J Biol Chem.285:37909-919.
    • J Biol Chem. , vol.285 , pp. 37909-919
    • Ding, Y.1    Kim, J.K.2    Kim, S.I.3    Na, H.J.4    Jun, S.Y.5    Lee, S.J.6
  • 161
    • 71549124671 scopus 로고    scopus 로고
    • Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells
    • Kiyono K., Suzuki H.I., Matsuyama H., Morishita Y., Komuro A., Kano M.R., et al. Autophagy is activated by TGF-beta and potentiates TGF-beta-mediated growth inhibition in human hepatocellular carcinoma cells. Cancer Res 2009, 69:8844-8852.
    • (2009) Cancer Res , vol.69 , pp. 8844-8852
    • Kiyono, K.1    Suzuki, H.I.2    Matsuyama, H.3    Morishita, Y.4    Komuro, A.5    Kano, M.R.6
  • 162
    • 31144471231 scopus 로고    scopus 로고
    • Apoptosis and autophagy induced by TGF-B1 in bovine mammary epithelial Bme-UV1 cells
    • Gajewska M., Gajkowska B., Motyl T. Apoptosis and autophagy induced by TGF-B1 in bovine mammary epithelial Bme-UV1 cells. J Physiol Pharmacol 2005, 56(Suppl. 3):143-157.
    • (2005) J Physiol Pharmacol , vol.56 , Issue.SUPPL. 3 , pp. 143-157
    • Gajewska, M.1    Gajkowska, B.2    Motyl, T.3
  • 163
    • 77957252460 scopus 로고    scopus 로고
    • Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells
    • Koesters R, Kaissling B, Lehir M, Picard N, Theilig F, Gebhardt R, et al. Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol. 177:632-43.
    • Am J Pathol. , vol.177 , pp. 632-43
    • Koesters, R.1    Kaissling, B.2    Lehir, M.3    Picard, N.4    Theilig, F.5    Gebhardt, R.6
  • 164
    • 31144476910 scopus 로고    scopus 로고
    • Cathepsins and bid are involved in the molecular switch between apoptosis and autophagy in breast cancer Mcf-7 cells exposed to camptothecin
    • Lamparska-Przybysz M., Gajkowska B., Motyl T. Cathepsins and bid are involved in the molecular switch between apoptosis and autophagy in breast cancer Mcf-7 cells exposed to camptothecin. J Physiol Pharmacol 2005, 56(Suppl. 3):159-179.
    • (2005) J Physiol Pharmacol , vol.56 , Issue.SUPPL. 3 , pp. 159-179
    • Lamparska-Przybysz, M.1    Gajkowska, B.2    Motyl, T.3
  • 166
    • 79551621417 scopus 로고    scopus 로고
    • Autophagy, reactive oxygen species and the fate of mammalian cells
    • Szumiel I. Autophagy, reactive oxygen species and the fate of mammalian cells. Free Radic Res 2011, 45:253-265.
    • (2011) Free Radic Res , vol.45 , pp. 253-265
    • Szumiel, I.1
  • 167
    • 53749087325 scopus 로고    scopus 로고
    • Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease
    • Chen Z.H., Kim H.P., Sciurba F.C., Lee S.J., Feghali-Bostwick C., Stolz D.B., et al. Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease. PLoS One 2008, 3:e3316.
    • (2008) PLoS One , vol.3
    • Chen, Z.H.1    Kim, H.P.2    Sciurba, F.C.3    Lee, S.J.4    Feghali-Bostwick, C.5    Stolz, D.B.6
  • 168
    • 0028897842 scopus 로고
    • Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis
    • Cserjesi P., Brown D., Ligon K.L., Lyons G.E., Copeland N.G., Gilbert D.J., et al. Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Development 1995, 121:1099-1110.
    • (1995) Development , vol.121 , pp. 1099-1110
    • Cserjesi, P.1    Brown, D.2    Ligon, K.L.3    Lyons, G.E.4    Copeland, N.G.5    Gilbert, D.J.6
  • 169
    • 53549090696 scopus 로고    scopus 로고
    • Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1
    • Kim H.P., Wang X., Chen Z.H., Lee S.J., Huang M.H., Wang Y., et al. Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1. Autophagy 2008, 4:887-895.
    • (2008) Autophagy , vol.4 , pp. 887-895
    • Kim, H.P.1    Wang, X.2    Chen, Z.H.3    Lee, S.J.4    Huang, M.H.5    Wang, Y.6
  • 170
    • 78149476302 scopus 로고    scopus 로고
    • Identification of an autophagy defect in smokers' alveolar macrophages
    • Monick M.M., Powers L.S., Walters K., Lovan N., Zhang M., Gerke A., et al. Identification of an autophagy defect in smokers' alveolar macrophages. J Immunol 2010, 185:5425-5435.
    • (2010) J Immunol , vol.185 , pp. 5425-5435
    • Monick, M.M.1    Powers, L.S.2    Walters, K.3    Lovan, N.4    Zhang, M.5    Gerke, A.6
  • 171
    • 0034776944 scopus 로고    scopus 로고
    • Analysis of the tendon cell fate using scleraxis, a specific marker for tendons and ligaments
    • Schweitzer R., Chyung J.H., Murtaugh L.C., Brent A.E., Rosen V., Olson E.N., et al. Analysis of the tendon cell fate using scleraxis, a specific marker for tendons and ligaments. Development 2001, 128:3855-3866.
    • (2001) Development , vol.128 , pp. 3855-3866
    • Schweitzer, R.1    Chyung, J.H.2    Murtaugh, L.C.3    Brent, A.E.4    Rosen, V.5    Olson, E.N.6
  • 172
    • 0242417166 scopus 로고    scopus 로고
    • A somitic compartment of tendon progenitors
    • Brent A.E., Schweitzer R., Tabin C.J. A somitic compartment of tendon progenitors. Cell. 2003, 113:235-248.
    • (2003) Cell. , vol.113 , pp. 235-248
    • Brent, A.E.1    Schweitzer, R.2    Tabin, C.J.3
  • 173
    • 67649130137 scopus 로고    scopus 로고
    • The basic helix-loop-helix transcription factor scleraxis regulates fibroblast collagen synthesis
    • Espira L., Lamoureux L., Jones S.C., Gerard R.D., Dixon I.M., Czubryt M.P. The basic helix-loop-helix transcription factor scleraxis regulates fibroblast collagen synthesis. J Mol Cell Cardiol 2009, 47:188-195.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 188-195
    • Espira, L.1    Lamoureux, L.2    Jones, S.C.3    Gerard, R.D.4    Dixon, I.M.5    Czubryt, M.P.6
  • 174
    • 23744516948 scopus 로고    scopus 로고
    • Role of the basic helix-loop-helix transcription factor, scleraxis, in the regulation of sertoli cell function and differentiation
    • Muir T., Sadler-Riggleman I., Skinner M.K. Role of the basic helix-loop-helix transcription factor, scleraxis, in the regulation of sertoli cell function and differentiation. Mol Endocrinol 2005, 19:2164-2174.
    • (2005) Mol Endocrinol , vol.19 , pp. 2164-2174
    • Muir, T.1    Sadler-Riggleman, I.2    Skinner, M.K.3
  • 175
    • 0030691086 scopus 로고    scopus 로고
    • Overexpression of a single helix-loop-helix-type transcription factor, scleraxis, enhances aggrecan gene expression in osteoblastic osteosarcoma Ros17/2.8 cells
    • Liu Y., Watanabe H., Nifuji A., Yamada Y., Olson E.N., Noda M. Overexpression of a single helix-loop-helix-type transcription factor, scleraxis, enhances aggrecan gene expression in osteoblastic osteosarcoma Ros17/2.8 cells. J Biol Chem 1997, 272:29880-29885.
    • (1997) J Biol Chem , vol.272 , pp. 29880-29885
    • Liu, Y.1    Watanabe, H.2    Nifuji, A.3    Yamada, Y.4    Olson, E.N.5    Noda, M.6
  • 176
    • 2442639010 scopus 로고    scopus 로고
    • Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos
    • Lincoln J., Alfieri C.M., Yutzey K.E. Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos. Dev Dyn 2004, 230:239-250.
    • (2004) Dev Dyn , vol.230 , pp. 239-250
    • Lincoln, J.1    Alfieri, C.M.2    Yutzey, K.E.3
  • 177
    • 34547117141 scopus 로고    scopus 로고
    • Scleraxis and Nfatc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts
    • Lejard V., Brideau G., Blais F., Salingcarnboriboon R., Wagner G., Roehrl M.H., et al. Scleraxis and Nfatc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts. J Biol Chem 2007, 282:17665-17675.
    • (2007) J Biol Chem , vol.282 , pp. 17665-17675
    • Lejard, V.1    Brideau, G.2    Blais, F.3    Salingcarnboriboon, R.4    Wagner, G.5    Roehrl, M.H.6
  • 178
    • 34547767687 scopus 로고    scopus 로고
    • Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons
    • Murchison N.D., Price B.A., Conner D.A., Keene D.R., Olson E.N., Tabin C.J., et al. Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons. Development 2007, 134:2697-2708.
    • (2007) Development , vol.134 , pp. 2697-2708
    • Murchison, N.D.1    Price, B.A.2    Conner, D.A.3    Keene, D.R.4    Olson, E.N.5    Tabin, C.J.6
  • 179
    • 0035891664 scopus 로고    scopus 로고
    • Remodeling in asthma and chronic obstructive lung disease
    • Jeffery P.K. Remodeling in asthma and chronic obstructive lung disease. Am J Respir Crit Care Med 2001, 164:S28-S38.
    • (2001) Am J Respir Crit Care Med , vol.164
    • Jeffery, P.K.1
  • 181
    • 0030460706 scopus 로고    scopus 로고
    • Response of airway smooth muscle cells to TGF-beta 1: effects on growth and synthesis of glycosaminoglycans
    • Black P.N., Young P.G., Skinner S.J. Response of airway smooth muscle cells to TGF-beta 1: effects on growth and synthesis of glycosaminoglycans. Am J Physiol 1996, 271:L910-L917.
    • (1996) Am J Physiol , vol.271
    • Black, P.N.1    Young, P.G.2    Skinner, S.J.3
  • 182
    • 44949175921 scopus 로고    scopus 로고
    • The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentary
    • Anthwal N., Chai Y., Tucker A.S. The role of transforming growth factor-beta signalling in the patterning of the proximal processes of the murine dentary. Dev Dyn 2008, 237:1604-1613.
    • (2008) Dev Dyn , vol.237 , pp. 1604-1613
    • Anthwal, N.1    Chai, Y.2    Tucker, A.S.3
  • 183
    • 33645806742 scopus 로고    scopus 로고
    • Fibrosis in heart disease: understanding the role of transforming growth factor-beta in cardiomyopathy, valvular disease and arrhythmia
    • Khan R., Sheppard R. Fibrosis in heart disease: understanding the role of transforming growth factor-beta in cardiomyopathy, valvular disease and arrhythmia. Immunology 2006, 118:10-24.
    • (2006) Immunology , vol.118 , pp. 10-24
    • Khan, R.1    Sheppard, R.2
  • 186
    • 0023584505 scopus 로고
    • Comparison of different autophagic vacuoles with regard to ultrastructure, enzymatic composition, and degradation capacity-formation of crinosomes
    • Glaumann H., Ahlberg J. Comparison of different autophagic vacuoles with regard to ultrastructure, enzymatic composition, and degradation capacity-formation of crinosomes. Exp Mol Pathol 1987, 47:346-362.
    • (1987) Exp Mol Pathol , vol.47 , pp. 346-362
    • Glaumann, H.1    Ahlberg, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.