-
1
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
M. J. Evans, M. H. Kaufman, Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156 (1981).
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
2
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
J. A. Thomson, J. Itskovitz-Eldor, S. S. Shapiro, M. A. Waknitz, J. J. Swiergiel, V. S. Marshall, J. M. Jones, Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (1998).
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
3
-
-
78149487692
-
Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues
-
J. H. Hanna, K. Saha, R. Jaenisch, Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues. Cell 143, 508-525 (2010).
-
(2010)
Cell
, vol.143
, pp. 508-525
-
-
Hanna, J.H.1
Saha, K.2
Jaenisch, R.3
-
4
-
-
77953365784
-
Extrinsic regulation of pluripotent stem cells
-
M. F. Pera, P. P. Tam, Extrinsic regulation of pluripotent stem cells. Nature 465, 713-720 (2010).
-
(2010)
Nature
, vol.465
, pp. 713-720
-
-
Pera, M.F.1
Tam, P.P.2
-
5
-
-
82355186665
-
Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming
-
10.1007/s12015-011-9275-1
-
T. Miki, S.-y. Yasuda, M. Kahn, Wnt/β-catenin signaling in embryonic stem cell self-renewal and somatic cell reprogramming. Stem Cell Rev. Rep. 10.1007/s12015-011-9275-1 (2011).
-
(2011)
Stem Cell Rev. Rep.
-
-
Miki, T.1
Yasuda, S.-Y.2
Kahn, M.3
-
6
-
-
34249311572
-
Functional redundancy of GSK-3α and GSK-3β in Wnt/β-catenin signaling shown by using an allelic series of embryonic stem cell lines
-
B. W. Doble, S. Patel, G. A. Wood, L. K. Kockeritz, J. R. Woodgett, Functional redundancy of GSK-3α and GSK-3β in Wnt/β-catenin signaling shown by using an allelic series of embryonic stem cell lines. Dev. Cell 12, 957-971 (2007).
-
(2007)
Dev. Cell
, vol.12
, pp. 957-971
-
-
Doble, B.W.1
Patel, S.2
Wood, G.A.3
Kockeritz, L.K.4
Woodgett, J.R.5
-
7
-
-
67349183976
-
Metastable pluripotent states in NOD-mouse-derived ESCs
-
J. Hanna, S. Markoulaki, M. Mitalipova, A. W. Cheng, J. P. Cassady, J. Staerk, B. W. Carey, C. J. Lengner, R. Foreman, J. Love, Q. Gao, J. Kim, R. Jaenisch, Metastable pluripotent states in NOD-mouse-derived ESCs. Cell Stem Cell 4, 513-524 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, pp. 513-524
-
-
Hanna, J.1
Markoulaki, S.2
Mitalipova, M.3
Cheng, A.W.4
Cassady, J.P.5
Staerk, J.6
Carey, B.W.7
Lengner, C.J.8
Foreman, R.9
Love, J.10
Gao, Q.11
Kim, J.12
Jaenisch, R.13
-
8
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
N. Sato, L. Meijer, L. Skaltsounis, P. Greengard, A. H. Brivanlou, Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat. Med. 10, 55-63 (2004).
-
(2004)
Nat. Med.
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
9
-
-
44349170450
-
The ground state of embryonic stem cell self-renewal
-
Q. L. Ying, J. Wray, J. Nichols, L. Batlle-Morera, B. Doble, J. Woodgett, P. Cohen, A. Smith, The ground state of embryonic stem cell self-renewal. Nature 453, 519-523 (2008).
-
(2008)
Nature
, vol.453
, pp. 519-523
-
-
Ying, Q.L.1
Wray, J.2
Nichols, J.3
Batlle-Morera, L.4
Doble, B.5
Woodgett, J.6
Cohen, P.7
Smith, A.8
-
10
-
-
30544450976
-
WNT/β-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells
-
J. Hao, T. G. Li, X. Qi, D. F. Zhao, G. Q. Zhao, WNT/β-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells. Dev. Biol. 290, 81-91 (2006).
-
(2006)
Dev. Biol.
, vol.290
, pp. 81-91
-
-
Hao, J.1
Li, T.G.2
Qi, X.3
Zhao, D.F.4
Zhao, G.Q.5
-
11
-
-
33646845948
-
Wnt3a but not wnt11 supports self-renewal of embryonic stem cells
-
D. K. Singla, D. J. Schneider, M. M. LeWinter, B. E. Sobel, wnt3a but not wnt11 supports self-renewal of embryonic stem cells. Biochem. Biophys. Res. Commun. 345, 789-795 (2006).
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.345
, pp. 789-795
-
-
Singla, D.K.1
Schneider, D.J.2
LeWinter, M.M.3
Sobel, B.E.4
-
12
-
-
80052475509
-
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
-
D. T. Berge, D. Kurek, T. Blauwkamp, W. Koole, A. Maas, E. Eroglu, R. K. Siu, R. Nusse, Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. Nat. Cell Biol. 13, 1070-1075 (2011).
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1070-1075
-
-
Berge, D.T.1
Kurek, D.2
Blauwkamp, T.3
Koole, W.4
Maas, A.5
Eroglu, E.6
Siu, R.K.7
Nusse, R.8
-
13
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-tasking kinase
-
B. W. Doble, J. R. Woodgett, GSK-3: Tricks of the trade for a multi-tasking kinase. J. Cell Sci. 116, 1175-1186 (2003).
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
14
-
-
70349932747
-
Towards an integrated view of Wnt signaling in development
-
R. Van Amerongen, R. Nusse, Towards an integrated view of Wnt signaling in development. Development 136, 3205-3214 (2009).
-
(2009)
Development
, vol.136
, pp. 3205-3214
-
-
Van Amerongen, R.1
Nusse, R.2
-
15
-
-
33746808398
-
Wnt/β-catenin signaling in development and disease
-
H. Clevers, Wnt/β-catenin signaling in development and disease. Cell 127, 469-480 (2006).
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
16
-
-
35548941791
-
β-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells
-
R. Anton, H. A. Kestler, M. Kühl, β-catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells. FEBS Lett. 581, 5247-5254 (2007).
-
(2007)
FEBS Lett.
, vol.581
, pp. 5247-5254
-
-
Anton, R.1
Kestler, H.A.2
Kühl, M.3
-
17
-
-
70349865021
-
Abrogation of E-cadherin-mediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal
-
F. Soncin, L. Mohamet, D. Eckardt, S. Ritson, A. M. Eastham, N. Bobola, A. Russell, S. Davies, R. Kemler, C. L. Merry, C. M. Ward, Abrogation of E-cadherin-mediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal. Stem Cells 27, 2069-2080 (2009).
-
(2009)
Stem Cells
, vol.27
, pp. 2069-2080
-
-
Soncin, F.1
Mohamet, L.2
Eckardt, D.3
Ritson, S.4
Eastham, A.M.5
Bobola, N.6
Russell, A.7
Davies, S.8
Kemler, R.9
Merry, C.L.10
Ward, C.M.11
-
18
-
-
78149337402
-
Canonical Wnt/β-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression
-
R. T. Wagner, X. Xu, F. Yi, B. J. Merrill, A. J. Cooney, Canonical Wnt/β-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression. Stem Cells 28, 1794-1804 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 1794-1804
-
-
Wagner, R.T.1
Xu, X.2
Yi, F.3
Merrill, B.J.4
Cooney, A.J.5
-
19
-
-
79551594937
-
β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism
-
K. F. Kelly, D. Y. Ng, G. Jayakumaran, G. A. Wood, H. Koide, B. W. Doble, β-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism. Cell Stem Cell 8, 214-227 (2011).
-
(2011)
Cell Stem Cell
, vol.8
, pp. 214-227
-
-
Kelly, K.F.1
Ng, D.Y.2
Jayakumaran, G.3
Wood, G.A.4
Koide, H.5
Doble, B.W.6
-
20
-
-
79959999016
-
Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation
-
N. Lyashenko, M. Winter, D. Migliorini, T. Biechele, R. T. Moon, C. Hartmann, Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation. Nat. Cell Biol. 13, 753-761 (2011).
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 753-761
-
-
Lyashenko, N.1
Winter, M.2
Migliorini, D.3
Biechele, T.4
Moon, R.T.5
Hartmann, C.6
-
21
-
-
79959950773
-
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
-
J. Wray, T. Kalkan, S. Gomez-Lopez, D. Eckardt, A. Cook, R. Kemler, A. Smith, Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat. Cell Biol. 13, 838-845 (2011).
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 838-845
-
-
Wray, J.1
Kalkan, T.2
Gomez-Lopez, S.3
Eckardt, D.4
Cook, A.5
Kemler, R.6
Smith, A.7
-
22
-
-
79959963618
-
Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal
-
F. Yi, L. Pereira, J. A. Hoffman, B. R. Shy, C. M. Yuen, D. R. Liu, B. J. Merrill, Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal. Nat. Cell Biol. 13, 762-770 (2011).
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 762-770
-
-
Yi, F.1
Pereira, L.2
Hoffman, J.A.3
Shy, B.R.4
Yuen, C.M.5
Liu, D.R.6
Merrill, B.J.7
-
23
-
-
0034614937
-
Requirement for β-catenin in anterior-posterior axis formation in mice
-
J. Huelsken, R. Vogel, V. Brinkmann, B. Erdmann, C. Birchmeier, W. Birchmeier, Requirement for β-catenin in anterior-posterior axis formation in mice. J. Cell Biol. 148, 567-578 (2000).
-
(2000)
J. Cell Biol.
, vol.148
, pp. 567-578
-
-
Huelsken, J.1
Vogel, R.2
Brinkmann, V.3
Erdmann, B.4
Birchmeier, C.5
Birchmeier, W.6
-
24
-
-
34447528757
-
New cell lines from mouse epiblast share defining features with human embryonic stem cells
-
P. J. Tesar, J. G. Chenoweth, F. A. Brook, T. J. Davies, E. P. Evans, D. L. Mack, R. L. Gardner, R. D. McKay, New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448, 196-199 (2007).
-
(2007)
Nature
, vol.448
, pp. 196-199
-
-
Tesar, P.J.1
Chenoweth, J.G.2
Brook, F.A.3
Davies, T.J.4
Evans, E.P.5
Mack, D.L.6
Gardner, R.L.7
McKay, R.D.8
-
25
-
-
66049117813
-
Naive and primed pluripotent states
-
J. Nichols, A. Smith, Naive and primed pluripotent states. Cell Stem Cell 4, 487-492 (2009).
-
(2009)
Cell Stem Cell
, vol.4
, pp. 487-492
-
-
Nichols, J.1
Smith, A.2
-
26
-
-
0030999806
-
Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
-
M. Van de Wetering, R. Cavallo, D. Dooijes, M. Van Beest, J. Van Es, J. Loureiro, A. Ypma, D. Hursh, T. Jones, A. Bejsovec, M. Peifer, M. Mortin, H. Clevers, Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88, 789-799 (1997).
-
(1997)
Cell
, vol.88
, pp. 789-799
-
-
Van De Wetering, M.1
Cavallo, R.2
Dooijes, D.3
Van Beest, M.4
Van Es, J.5
Loureiro, J.6
Ypma, A.7
Hursh, D.8
Jones, T.9
Bejsovec, A.10
Peifer, M.11
Mortin, M.12
Clevers, H.13
-
27
-
-
0030000980
-
Cadherin-catenin complex: Protein interactions and their implications for cadherin function
-
H. Aberle, H. Schwartz, R. Kemler, Cadherin-catenin complex: Protein interactions and their implications for cadherin function. J. Cell. Biochem. 61, 514-523 (1996).
-
(1996)
J. Cell. Biochem.
, vol.61
, pp. 514-523
-
-
Aberle, H.1
Schwartz, H.2
Kemler, R.3
-
28
-
-
0031856533
-
Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with β-catenin
-
S. C. Hsu, J. Galceran, R. Grosschedl, Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with β-catenin. Mol. Cell. Biol. 18, 4807-4818 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4807-4818
-
-
Hsu, S.C.1
Galceran, J.2
Grosschedl, R.3
-
29
-
-
42549120253
-
Pygopus and the Wnt signaling pathway: A diverse set of connections
-
S. Jessen, B. Gu, X. Dai, Pygopus and the Wnt signaling pathway: A diverse set of connections. Bioessays 30, 448-456 (2008).
-
(2008)
Bioessays
, vol.30
, pp. 448-456
-
-
Jessen, S.1
Gu, B.2
Dai, X.3
-
30
-
-
22344441322
-
Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells
-
W. E. Lowry, C. Blanpain, J. A. Nowak, G. Guasch, L. Lewis, E. Fuchs, Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells. Genes Dev. 19, 1596-1611 (2005).
-
(2005)
Genes Dev.
, vol.19
, pp. 1596-1611
-
-
Lowry, W.E.1
Blanpain, C.2
Nowak, J.A.3
Guasch, G.4
Lewis, L.5
Fuchs, E.6
-
31
-
-
33749645068
-
Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal
-
L. Pereira, F. Yi, B. J. Merrill, Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal. Mol. Cell. Biol. 26, 7479-7491 (2006).
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 7479-7491
-
-
Pereira, L.1
Yi, F.2
Merrill, B.J.3
-
32
-
-
41149174852
-
Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells
-
M. F. Cole, S. E. Johnstone, J. J. Newman, M. H. Kagey, R. A. Young, Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells. Genes Dev. 22, 746-755 (2008).
-
(2008)
Genes Dev.
, vol.22
, pp. 746-755
-
-
Cole, M.F.1
Johnstone, S.E.2
Newman, J.J.3
Kagey, M.H.4
Young, R.A.5
-
33
-
-
48449105489
-
Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal
-
F. Yi, L. Pereira, B. J. Merrill, Tcf3 functions as a steady-state limiter of transcriptional programs of mouse embryonic stem cell self-renewal. Stem Cells 26, 1951-1960 (2008).
-
(2008)
Stem Cells
, vol.26
, pp. 1951-1960
-
-
Yi, F.1
Pereira, L.2
Merrill, B.J.3
-
34
-
-
79955138850
-
A PiggyBac-based recessive screening method to identify pluripotency regulators
-
G. Guo, Y. Huang, P. Humphreys, X. Wang, A. Smith, A PiggyBac-based recessive screening method to identify pluripotency regulators. PLoS ONE 6, e18189 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Guo, G.1
Huang, Y.2
Humphreys, P.3
Wang, X.4
Smith, A.5
-
35
-
-
0031836914
-
TCF: Transcriptional activator or repressor?
-
M. Bienz, TCF: Transcriptional activator or repressor? Curr. Opin. Cell Biol. 10, 366-372 (1998).
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 366-372
-
-
Bienz, M.1
-
36
-
-
0036124896
-
TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling
-
H. Brantjes, N. Barker, J. Van Es, H. Clevers, TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling. Biol. Chem. 383, 255-261 (2002).
-
(2002)
Biol. Chem.
, vol.383
, pp. 255-261
-
-
Brantjes, H.1
Barker, N.2
Van Es, J.3
Clevers, H.4
-
37
-
-
0035033521
-
β-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer
-
K. Hovanes, T. W. Li, J. E. Munguia, T. Truong, T. Milovanovic, J. Lawrence Marsh, R. F. Holcombe, M. L. Waterman, β-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nat. Genet. 28, 53-57 (2001).
-
(2001)
Nat. Genet.
, vol.28
, pp. 53-57
-
-
Hovanes, K.1
Li, T.W.2
Munguia, J.E.3
Truong, T.4
Milovanovic, T.5
Lawrence Marsh, J.6
Holcombe, R.F.7
Waterman, M.L.8
-
38
-
-
70349554461
-
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia
-
H. Nguyen, B. J. Merrill, L. Polak, M. Nikolova, M. Rendl, T. M. Shaver, H. A. Pasolli, E. Fuchs, Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat. Genet. 41, 1068-1075 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1068-1075
-
-
Nguyen, H.1
Merrill, B.J.2
Polak, L.3
Nikolova, M.4
Rendl, M.5
Shaver, T.M.6
Pasolli, H.A.7
Fuchs, E.8
-
39
-
-
0035395874
-
Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin
-
B. J. Merrill, U. Gat, R. DasGupta, E. Fuchs, Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin. Genes Dev. 15, 1688-1705 (2001).
-
(2001)
Genes Dev.
, vol.15
, pp. 1688-1705
-
-
Merrill, B.J.1
Gat, U.2
DasGupta, R.3
Fuchs, E.4
-
40
-
-
0032718124
-
Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation
-
R. DasGupta, E. Fuchs, Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation. Development 126, 4557-4568 (1999).
-
(1999)
Development
, vol.126
, pp. 4557-4568
-
-
DasGupta, R.1
Fuchs, E.2
-
41
-
-
33644763022
-
The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes
-
J. Sierra, T. Yoshida, C. A. Joazeiro, K. A. Jones, The APC tumor suppressor counteracts β-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev. 20, 586-600 (2006).
-
(2006)
Genes Dev.
, vol.20
, pp. 586-600
-
-
Sierra, J.1
Yoshida, T.2
Joazeiro, C.A.3
Jones, K.A.4
-
42
-
-
77957876629
-
Regulation of TCF3 by Wntdependent phosphorylation during vertebrate axis specification
-
H. Hikasa, J. Ezan, K. Itoh, X. Li, M. W. Klymkowsky, S. Y. Sokol, Regulation of TCF3 by Wntdependent phosphorylation during vertebrate axis specification. Dev. Cell 19, 521-532 (2010).
-
(2010)
Dev. Cell
, vol.19
, pp. 521-532
-
-
Hikasa, H.1
Ezan, J.2
Itoh, K.3
Li, X.4
Klymkowsky, M.W.5
Sokol, S.Y.6
-
43
-
-
79953305300
-
Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2
-
H. Hikasa, S. Y. Sokol, Phosphorylation of TCF proteins by homeodomain-interacting protein kinase 2. J. Biol. Chem. 286, 12093-12100 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12093-12100
-
-
Hikasa, H.1
Sokol, S.Y.2
-
44
-
-
80053512525
-
-
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Acknowledgments: We thank M. Waterman for discussions and critical reading of the manuscript. Funding: The Dai laboratory has been funded by grants from the NIH (R01-AR47320 and R01-GM083089). K.W. is a recipient of a U.S. Department of Defense postdoctoral fellowship (W81XWH-10-1-0383).
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