The role of the receptor for advanced glycation end-products in lung fibrosis

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 293, Issue 6, 2007, Pages

  He, Mei ^a   Kubo, Hiroshi ^a   Ishizawa, Kota ^a   Hegab, Ahmed E ^a   Yamamoto, Yasuhiko ^b   Yamamoto, Hiroshi ^b   Yamaya, Mutsuo ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

Alveolar type II epithelial cell; Epithelial mesenchymal transition; HMGB 1; Pulmonary fibrosis; Receptor for advanced glycation end products

Indexed keywords

BLEOMYCIN; HIGH MOBILITY GROUP B1 PROTEIN; PLATELET DERIVED GROWTH FACTOR; PROTEIN RAGE; RECEPTOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HISTOPATHOLOGY; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; LUNG INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ANIMALS; APOPTOSIS; BLEOMYCIN; BLOOD CELL COUNT; BRONCHOALVEOLAR LAVAGE FLUID; CELL DIFFERENTIATION; CELL MEMBRANE PERMEABILITY; EPITHELIAL CELLS; HMGB1 PROTEIN; IN SITU NICK-END LABELING; LUNG; MESODERM; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; PLATELET-DERIVED GROWTH FACTOR; PULMONARY FIBROSIS; RECEPTORS, IMMUNOLOGIC; SURVIVAL RATE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 37149008763     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00075.2007     Document Type: Article

References (43)

1. Abeyama K, Stern DM, Ito Y, Kawahara K, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I. The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism. J Clin Invest 115: 1267-1274, 2005.
2. Adamson IYR, Bowden DH. The pathogenesis of bleomycin-induced pulmonary fibrosis in mice. Am J Pathol 77: 185-197, 1974.
3. Ashcroft T, Simpson JM, Timbrell V. Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol 41: 467-470, 1988.
4. Bohlender JM, Franke S, Stein G, Wolf G. Advanced glycation end-products and the kidney. Am J Physiol Renal Physiol 289: F645-F659, 2005.
5. Brett J, Schmidt AM, Yan SD, Zou YS, Weidman E, Pinsky D, Nowygrod R, Neeper M, Przysiecki C, Shaw A, Migheli A, Stern D. Survey of the distribution of a newly characterized receptor for advanced glycation end-products in tissues. Am J Pathol 143: 1699-1712, 1993.
6. Chilosi M, Poletti V, Zamo A, Lestani M, Montagna L, Piccoli P, Pedron S, Bertaso M, Scarpa A, Murer B, Cancellieri A, Maestro R, Semenzato G, Doglioni C. Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am J Pathol 162: 1495-1502, 2003.
7. Dobbs LG. Isolation and culture of alveolar type II cells. Am J Physiol Lung Cell Mol Physiol 258: L134-L147, 1990.
8. Ebina M, Shibata N, Konishi K, Ishizaka A, Hashimoto S, Maruyama I, Nukiwa T. High mobility group protein (HMGB1) as a possible mediator of acute exacerbation in idiopathic pulmonary fibrosis. Proc Am Thorac Soc 2: A638, 2005.
9. Erlandsson Harris H, Andersson U. Mini-review: the nuclear protein HMGB1 as a proinflammatory mediator. Eur J Immunol 34: 1503-1512, 2004.
10. Flanders KC. Smad3 as a mediator of the fibrotic response. Int J Exp Pathol 85: 47-64, 2004.
11. Giri SN, Hyde DM, Hollinger MA. Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice. Thorax 48: 959-966, 1993.
12. Hamada N, Yamada M, Maeyama T, Yoshimi M, Yamada S, Fukumoto J, Nakanishi Y. The role of high mobility group box 1 protein (HMGB1) in pulmonary fibrosis. Proc Am Thorac Soc 2: A214, 2005.
13. Hanford L, Fattman C, Shaefer L, Enghild J, Valnickova Z, Oury T. Regulation of receptor for advanced glycation end-products during bleomycin-induced lung injury. Am J Respir Cell Mol Biol 29: S77-S81, 2003.
14. Hashimoto N, Jin H, Liu T, Chensue SW, Phan SH. Bone marrow-derived progenitor cells in pulmonary fibrosis. J Clin Invest 113: 243-252, 2004.
15. Huttunen HJ, Fages C, Rauvala H. Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways. J Biol Chem 274: 19919-19924, 1999.
16. Huttunen HJ, Rauvala H. Amphoterin as an extracellular regulator of cell motility: from discovery to disease. J Intern Med 255: 351-366, 2004.
17. Iwano M, Plieth D, Danoff TM, Xue C, Okada H, Neilson EG. Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 110: 341-350, 2002.
18. Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784, 2003.
19. Kasai H, Allen JT, Mason RM, Kamimura T, Zhang Z. TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir Res 6: 56, 2005.
20. Kulkarni AB, Huh CG, Becker D, Geiser A, Lyght M, Flanders KC, Roberts AB, Sporn MB, Ward JM, Karlsson S. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 90: 770-774, 1993.
21. Lawson WE, Polosukhin VV, Zoia O, Stathopoulos GT, Han W, Plieth D, Loyd JE, Neilson EG, Blackwell TS. Characterization of fibroblast-specific protein 1 in pulmonary fibrosis. Am J Respir Crit Care Med 171: 899-907, 2005.
22. Li JH, Wang W, Huang XR, Oldfield M, Schmidt AM, Cooper ME, Lan HY. Advanced glycation end-products induce tubular epithelial-myofibroblast transition through the RAGE-ERK1/2 MAP kinase signaling pathway. Am J Pathol 164: 1389-1397, 2004.
23. Li Y, Yang J, Dai C, Wu C, Liu Y. Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis. J Clin Invest 112: 503-516, 2003.
24. Matsuse T, Ohga E, Teramoto S, Fukayama M, Nagai R, Horiuchi S, Ouchi Y. Immunohistochemical localisation of advanced glycation end-products in pulmonary fibrosis. J Clin Pathol 51: 515-519, 1998.
25. Myint KM, Yamamoto Y, Doi T, Kato I, Harashima A, Yonekura H, Watanabe T, Shinohara H, Takeuchi M, Tsuneyama K, Hashimoto N, Asano M, Takasawa S, Okamoto H, Yamamoto H. RAGE control of diabetic nephropathy in a mouse model: effects of RAGE gene disruption and administration of low-molecular weight heparin. Diabetes 55: 2510-2522, 2006.
26. Oldfield MD, Bach LA, Forbes JM, Nikolic-Paterson D, McRobert A, Thallas V, Atkins RC, Osicka T, Jerums G, Cooper ME. Advanced glycation end-products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end-products (RAGE). J Clin Invest 108: 1853-1863, 2001.
27. Phan SH. The myofibroblast in pulmonary fibrosis. Chest 122: 286S-289S, 2002.
28. Schmidt AM, Yan SD, Yan SF, Stern DM. The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses. J Clin Invest 108: 949-955, 2001.
29. Schwenger V. GDP and AGE receptors: mechanisms of peritoneal damage. Contrib Nephrol 150: 77-83, 2006.
30. Selman M, King TE, Pardo A. Idiopathic pulmonary fibrosis: prevailing and evolving hypotheses about its pathogenesis and implications for therapy. Ann Intern Med 134: 136-151, 2001.
31. Shimizukawa M, Ebina M, Narumi K, Kikuchi T, Munakata H, Nukiwa T. Intratracheal gene transfer of decorin reduces subpleural fibroproliferation induced by bleomycin. Am J Physiol Lung Cell Mol Physiol 284: L526-L532, 2003.
32. Shirasawa M, Fujiwara N, Hirabayashi S, Ohno H, Iida J, Makita K, Hata Y. Receptor for advanced glycation end-products is a marker of type I lung alveolar cells. Genes Cells 9: 165-174, 2004.
33. Taguchi A, Blood DC, del Toro G, Canet A, Lee DC, Qu W, Tanji N, Lu Y, Lalla E, Fu C, Hofmann MA, Kislinger T, Ingram M, Lu A, Tanaka H, Hori O, Ogawa S, Stern DM, Schmidt AM. Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. Nature 405: 354-360, 2000.
34. Throckmorton DC, Brogden AP, Min B, Rasmussen H, Kashgarian M. PDGF and TGF-beta mediate collagen production by mesangial cells exposed to advanced glycosylation end-products. Kidney Int 48: 111-117, 1995.
35. Uchida T, Shirasawa M, Ware LB, Kojima K, Hata Y, Makita K, Mednick G, Matthay ZA, Matthay MA. Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med 173: 1008-1015, 2006.
36. Uhal BD, Joshi I, Hughes WF, Ramos C, Pardo A, Selman M. Alveolar epithelial cell death adjacent to underlying myofibroblasts in advanced fibrotic human lung. Am J Physiol Lung Cell Mol Physiol 275: L1192-L1199, 1998.
37. Vlassara H, Brownlee M, Manogue KR, Dinarello CA, Pasagian A. Cachectin/TNF and IL-1 induced by glucose-modified proteins: role in normal tissue remodeling. Science 240: 1546-1548, 1988.
38. Wang Q, Wang Y, Hyde DM, Gotwals PJ, Koteliansky VE, Ryan ST, Giri SN. Reduction of bleomycin induced lung fibrosis by transforming growth factor beta soluble receptor in hamsters. Thorax 54: 805-812, 1999.
39. White ES, Lazar MH, Thannickal VJ. Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis. J Pathol 201: 343-354, 2003.
40. Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, Borok Z. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 166: 1321-1332, 2005.
41. Yamada M, Kubo H, Kobayashi S, Ishizawa K, Sasaki H. Interferon-gamma: a key contributor to hyperoxia-induced lung injury in mice. Am J Physiol Lung Cell Mol Physiol 287: L1042-L1047, 2004.
42. Yang J, Liu Y. Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol 159: 1465-1475, 2001.
43. Yao HW, Xie QM, Chen JQ, Deng YM, Tang HF. TGF-beta1 induces alveolar epithelial to mesenchymal transition in vitro. Life Sci 76: 29-37, 2004.