메뉴 건너뛰기




Volumn 72, Issue 6, 2002, Pages 1084-1091

HMGB1 as a DNA-binding cytokine

Author keywords

Arthritis; Inflammation; Necrosis; Nuclear cytokine; RAGE ligand; Sepsis

Indexed keywords

CYTOKINE; HIGH MOBILITY GROUP B1 PROTEIN; RECOMBINANT PROTEIN;

EID: 0036908921     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (274)

References (50)
  • 1
    • 0015857760 scopus 로고
    • A new group of chromatin-associated proteins with a high content of acidic and basic amino acids
    • Goodwin, G. H., Sanders, C., Johns, E. W. (1973) A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur. J. Biochem. 38, 14-17.
    • (1973) Eur. J. Biochem. , vol.38 , pp. 14-17
    • Goodwin, G.H.1    Sanders, C.2    Johns, E.W.3
  • 2
    • 0032814140 scopus 로고    scopus 로고
    • Regulation of DNA-dependent activities by the functional motifs of the high mobility group chromosomal proteins
    • Bustin, M. (1999) Regulation of DNA-dependent activities by the functional motifs of the high mobility group chromosomal proteins. Mol. Cell. Biol. 19, 5237-5246.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5237-5246
    • Bustin, M.1
  • 3
    • 0034252817 scopus 로고    scopus 로고
    • Upwardly mobile proteins. The role of HMG proteins in chromatine structure, gene expression and neoplasia
    • Bianchi, M. E., Beltrame, M. (2000) Upwardly mobile proteins. The role of HMG proteins in chromatine structure, gene expression and neoplasia. EMBO Rep. 1, 109-119.
    • (2000) EMBO Rep. , vol.1 , pp. 109-119
    • Bianchi, M.E.1    Beltrame, M.2
  • 4
    • 0035282078 scopus 로고    scopus 로고
    • Revised nomenclature for high mobility group (HMG) chromosomal proteins
    • Bustin, M. (2001) Revised nomenclature for high mobility group (HMG) chromosomal proteins. Trends Biochem. Sci. 26, 152-153.
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 152-153
    • Bustin, M.1
  • 7
    • 0029563931 scopus 로고
    • Structure of the A-domain of HMG1 and its interaction with DNA as studied by heteronuclear three- and four-dimensional NMR spectroscopy
    • Hardman, C. H., Broadhurst, R. W., Raine, A. R. C., Grasser, K. D., Thomas, J. O., Laue, E. D. (1995) Structure of the A-domain of HMG1 and its interaction with DNA as studied by heteronuclear three- and four-dimensional NMR spectroscopy. Biochemistry, 34, 16596-16607.
    • (1995) Biochemistry , vol.34 , pp. 16596-16607
    • Hardman, C.H.1    Broadhurst, R.W.2    Raine, A.R.C.3    Grasser, K.D.4    Thomas, J.O.5    Laue, E.D.6
  • 8
    • 0025994836 scopus 로고
    • 30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane
    • Merenmies, J., Pihlaskari, R., Laitinen, J., Wartiovaara, J., Rauvala, H. (1991) 30-kDa heparin-binding protein of brain (amphoterin) involved in neurite outgrowth. Amino acid sequence and localization in the filopodia of the advancing plasma membrane. J. Biol. Chem. 266, 16722-16729.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16722-16729
    • Merenmies, J.1    Pihlaskari, R.2    Laitinen, J.3    Wartiovaara, J.4    Rauvala, H.5
  • 10
    • 0032522232 scopus 로고    scopus 로고
    • Hnzg4, a new member of the Hmg 1/2 gene family
    • Vaccari, T., Beltrame, M., Ferrari, S., Bianchi, M. E. (1998) Hnzg4, a new member of the Hmg 1/2 gene family. Genomics 49, 247-252.
    • (1998) Genomics , vol.49 , pp. 247-252
    • Vaccari, T.1    Beltrame, M.2    Ferrari, S.3    Bianchi, M.E.4
  • 12
    • 0032816123 scopus 로고    scopus 로고
    • Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes
    • Wang, H., Vishnubhakat, J. M., Bloom, O., Zhang, M., Ombrellino, M., Sama, A., Tracey, K. J. (1999) Proinflammatory cytokines (tumor necrosis factor and interleukin 1) stimulate release of high mobility group protein-1 by pituicytes. Surgery 126, 389-392.
    • (1999) Surgery , vol.126 , pp. 389-392
    • Wang, H.1    Vishnubhakat, J.M.2    Bloom, O.3    Zhang, M.4    Ombrellino, M.5    Sama, A.6    Tracey, K.J.7
  • 14
    • 0023651437 scopus 로고
    • Nucleotide sequence of rat liver HMG1 cDNA
    • Paonessa, G., Frank, R., Cortese, R. (1987) Nucleotide sequence of rat liver HMG1 cDNA. Nucleic Acids Res. 15, 9077-9081.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 9077-9081
    • Paonessa, G.1    Frank, R.2    Cortese, R.3
  • 15
    • 0024590341 scopus 로고
    • A human placental cDNA clone that encodes nonhistone chromosomal protein HMG1
    • Wen, L., Huang, J. K., Johnson, B. H., Reeck, G. R. (1989) A human placental cDNA clone that encodes nonhistone chromosomal protein HMG1. Nucleic Acids Res. 17, 1197-1214.
    • (1989) Nucleic Acids Res. , vol.17 , pp. 1197-1214
    • Wen, L.1    Huang, J.K.2    Johnson, B.H.3    Reeck, G.R.4
  • 16
    • 0024202114 scopus 로고
    • The adhesive and neurite-promoting molecule p30: Analysis of the amino-terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons
    • Rauvala, H., Merenmies, J., Pihlaskari, R., Korkolainen, M., Huhtala, M-L., Panula, P. (1988) The adhesive and neurite-promoting molecule p30: Analysis of the amino-terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons. J. Cell Biol. 107, 2293-2305.
    • (1988) J. Cell Biol. , vol.107 , pp. 2293-2305
    • Rauvala, H.1    Merenmies, J.2    Pihlaskari, R.3    Korkolainen, M.4    Huhtala, M.-L.5    Panula, P.6
  • 17
    • 0030586235 scopus 로고    scopus 로고
    • The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13
    • Ferrari, S., Finelli, P., Rocchi, M., Bianchi, M. E. (1996) The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13. Genomics 35, 367-371.
    • (1996) Genomics , vol.35 , pp. 367-371
    • Ferrari, S.1    Finelli, P.2    Rocchi, M.3    Bianchi, M.E.4
  • 18
    • 0033052037 scopus 로고    scopus 로고
    • The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycemia in newborn mice
    • Calogero, S., Grassi, F., Aguzzi, A., Voigtlander, T., Ferrier, P., Ferrari, S., Bianchi, M. E. (1999) The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycemia in newborn mice. Nat. Genet. 22, 276-280.
    • (1999) Nat. Genet. , vol.22 , pp. 276-280
    • Calogero, S.1    Grassi, F.2    Aguzzi, A.3    Voigtlander, T.4    Ferrier, P.5    Ferrari, S.6    Bianchi, M.E.7
  • 21
    • 0035316744 scopus 로고    scopus 로고
    • HMG1 rediscovered as a cytokine
    • Yang, H., Wang, H., Tracey, K. J. (2001) HMG1 rediscovered as a cytokine. Shock 15, 247-253.
    • (2001) Shock , vol.15 , pp. 247-253
    • Yang, H.1    Wang, H.2    Tracey, K.J.3
  • 22
    • 0000352873 scopus 로고
    • Galactosamine-induced sensitization of the lethal effects of endotoxin
    • Galanos, C., Freudenberg, M. A., Reutter, W. (1979) Galactosamine-induced sensitization of the lethal effects of endotoxin. Proc. Natl. Acad. Sci. USA 76, 5939-5943.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 5939-5943
    • Galanos, C.1    Freudenberg, M.A.2    Reutter, W.3
  • 23
    • 0023175468 scopus 로고
    • Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamin-treated mice
    • Lehmann, V., Freudenberg, M. A., Galanos, C. (1987) Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamin-treated mice. J. Exp. Med. 165, 657-663.
    • (1987) J. Exp. Med. , vol.165 , pp. 657-663
    • Lehmann, V.1    Freudenberg, M.A.2    Galanos, C.3
  • 24
    • 0030044634 scopus 로고    scopus 로고
    • Apoptotic cell death in the response of D-galactosamin-sensitized mice to lipopolysaccharide as an experimental endotoxic shock model
    • Morikawa, A., Sugijama, T., Kato, Y., Koide, N., Jiang, G. Z., Takahashi, K., Tamada, Y., Yokochi, T. (1996) Apoptotic cell death in the response of D-galactosamin-sensitized mice to lipopolysaccharide as an experimental endotoxic shock model. Infect. Immun. 64, 734-738.
    • (1996) Infect. Immun. , vol.64 , pp. 734-738
    • Morikawa, A.1    Sugijama, T.2    Kato, Y.3    Koide, N.4    Jiang, G.Z.5    Takahashi, K.6    Tamada, Y.7    Yokochi, T.8
  • 27
    • 0030273106 scopus 로고    scopus 로고
    • Melatonin administration following hemorrhagic shock decreases mortality from subsequent septic challenge
    • Wichmann, M. W., Haisken, J. M., Ayala, A., Chaudry, I. H. (1996) Melatonin administration following hemorrhagic shock decreases mortality from subsequent septic challenge. J. Surg. Res. 65, 109-114.
    • (1996) J. Surg. Res. , vol.65 , pp. 109-114
    • Wichmann, M.W.1    Haisken, J.M.2    Ayala, A.3    Chaudry, I.H.4
  • 29
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
    • Hori, O., Brett, J., Slattery, T., Cao, R., Zhang, J., Chen, J. X., Nagashima, M., Lundh, E. R., Vijay, S., Nitecki, D., et al. (1995) The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J. Biol. Chem. 270, 25752-25761.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3    Cao, R.4    Zhang, J.5    Chen, J.X.6    Nagashima, M.7    Lundh, E.R.8    Vijay, S.9    Nitecki, D.10
  • 31
    • 0026659883 scopus 로고
    • Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
    • Neeper, M., Schmidt, A. M., Brett, J., Yan, S. D., Wang, F., Pan, Y. C., Elliston, K., Stern, D., Shaw, A. (1992) Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. J. Biol. Chem. 267, 14998-15004.
    • (1992) J. Biol. Chem. , vol.267 , pp. 14998-15004
    • Neeper, M.1    Schmidt, A.M.2    Brett, J.3    Yan, S.D.4    Wang, F.5    Pan, Y.C.6    Elliston, K.7    Stern, D.8    Shaw, A.9
  • 32
    • 0034695098 scopus 로고    scopus 로고
    • The biology of the receptor for advanced glycation end products and its ligands
    • Schmidt, A. M., Yan, S. D., Yan, S. F., Stern, D. M. (2000) The biology of the receptor for advanced glycation end products and its ligands. Biochem. Biophys. Acta 1498, 99-111.
    • (2000) Biochem. Biophys. Acta , vol.1498 , pp. 99-111
    • Schmidt, A.M.1    Yan, S.D.2    Yan, S.F.3    Stern, D.M.4
  • 33
    • 0033538569 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways
    • Huttunen, H. J., Fages, C., Rauvala, H. (1999) Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-kappaB require the cytoplasmic domain of the receptor but different downstream signaling pathways. J. Biol. Chem. 274, 19919-19924.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19919-19924
    • Huttunen, H.J.1    Fages, C.2    Rauvala, H.3
  • 34
    • 0029738444 scopus 로고    scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis
    • Miyata, T., Hori, O., Zhang, J., Yan, S. D., Ferran, L., Iida, Y., Schmidt, A. M. (1996) The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis. J. Clin. Invest. 98, 1088-1094.
    • (1996) J. Clin. Invest. , vol.98 , pp. 1088-1094
    • Miyata, T.1    Hori, O.2    Zhang, J.3    Yan, S.D.4    Ferran, L.5    Iida, Y.6    Schmidt, A.M.7
  • 35
    • 0035911959 scopus 로고    scopus 로고
    • The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells
    • Degryse, B., Bonaldi, T., Scaffidi, P., Muller, S., Resnati, M., Sanvito, F., Arrigoni, G., Bianchi, M. E. (2001) The high mobility group (HMG) boxes of the nuclear protein HMG1 induce chemotaxis and cytoskeleton reorganization in rat smooth muscle cells. J. Cell Biol. 152, 1197-1206.
    • (2001) J. Cell Biol. , vol.152 , pp. 1197-1206
    • Degryse, B.1    Bonaldi, T.2    Scaffidi, P.3    Muller, S.4    Resnati, M.5    Sanvito, F.6    Arrigoni, G.7    Bianchi, M.E.8
  • 36
    • 0036566144 scopus 로고    scopus 로고
    • Stimulation of erythroleukaemia cell differentiation by extracellyular high-mobility group-box protein 1 is independent of the receptor for advanced glycation end-products
    • Sparatore, B., Pedrazzi, M., Passalacqua, M., Gaggero, D., Patrone, M., Pentremoli, S., Melloni, E. (2002) Stimulation of erythroleukaemia cell differentiation by extracellyular high-mobility group-box protein 1 is independent of the receptor for advanced glycation end-products. Biochem. J. 363, 529-535.
    • (2002) Biochem. J. , vol.363 , pp. 529-535
    • Sparatore, B.1    Pedrazzi, M.2    Passalacqua, M.3    Gaggero, D.4    Patrone, M.5    Pentremoli, S.6    Melloni, E.7
  • 37
    • 0023968323 scopus 로고
    • Interaction of a protein from rat liver nuclei with cruciform DNA
    • Bianchi, M. E. (1988) Interaction of a protein from rat liver nuclei with cruciform DNA. EMBO J. 7, 843-849.
    • (1988) EMBO J. , vol.7 , pp. 843-849
    • Bianchi, M.E.1
  • 38
    • 0026736041 scopus 로고
    • Neurite growth-promoting protein (amphoterin, p30) binds syndecan
    • Salmivirta, M., Rauvala, H., Elenius, K., Jalkanen, M. (1992) Neurite growth-promoting protein (amphoterin, p30) binds syndecan. Exp. Cell Res. 200, 444-451.
    • (1992) Exp. Cell Res. , vol.200 , pp. 444-451
    • Salmivirta, M.1    Rauvala, H.2    Elenius, K.3    Jalkanen, M.4
  • 39
    • 0035882102 scopus 로고    scopus 로고
    • New EMBO members' review: The double life of HMGB1 chromatin protein: Architectural factor and extracellular signal
    • Muller, S., Scaffidi, P., Deglyse, B., Bonaldi, T., Ronfani, L., Agresti, A., Beltrame, M., Bianchi, M. E. (2001) New EMBO members' review: The double life of HMGB1 chromatin protein: Architectural factor and extracellular signal. EMBO J. 16, 4337-4340.
    • (2001) EMBO J. , vol.16 , pp. 4337-4340
    • Muller, S.1    Scaffidi, P.2    Deglyse, B.3    Bonaldi, T.4    Ronfani, L.5    Agresti, A.6    Beltrame, M.7    Bianchi, M.E.8
  • 40
    • 0037062934 scopus 로고    scopus 로고
    • The release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • Scaffidi, P., Misteli, T., Bianchi, M. E. (2002) The release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 418, 191-195.
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 41
    • 0030908902 scopus 로고    scopus 로고
    • High mobility group 1 (HMG1) protein is not stably associated with the chromosomes of somatic cells
    • Falciola, L., Spada, F., Calogero, S., Längst, G., Voit, R., Grummt, I., Bianchi, M. E. (1997) High mobility group 1 (HMG1) protein is not stably associated with the chromosomes of somatic cells. J. Cell Biol. 137, 19-26.
    • (1997) J. Cell Biol. , vol.137 , pp. 19-26
    • Falciola, L.1    Spada, F.2    Calogero, S.3    Längst, G.4    Voit, R.5    Grummt, I.6    Bianchi, M.E.7
  • 43
    • 0035877013 scopus 로고    scopus 로고
    • An essential role of the NF-κB/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells
    • Li, M., Carpio, D. F., Zheng, Y., Bruzzo, P., Singh, V., Ouaaz, F., Medzhitov, M. R., Beg, A. A. (2001) An essential role of the NF-κB/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. J. Immunol. 166, 7128-7135.
    • (2001) J. Immunol. , vol.166 , pp. 7128-7135
    • Li, M.1    Carpio, D.F.2    Zheng, Y.3    Bruzzo, P.4    Singh, V.5    Ouaaz, F.6    Medzhitov, M.R.7    Beg, A.A.8
  • 44
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov, R. (2001) Toll-like receptors and innate immunity. Nat. Rev. Immunol. 1, 135-145.
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 46
    • 0034532366 scopus 로고    scopus 로고
    • Occurrence of amphoterin (HMG1) as an endogenous protein of human platelets that is exported to the cell surface upon platelet activation
    • Rouhiainen, A., Imai, S., Rauvala, H., Parkkinen, J. (2000) Occurrence of amphoterin (HMG1) as an endogenous protein of human platelets that is exported to the cell surface upon platelet activation. Thromb. Haemost. 84, 1087-1094.
    • (2000) Thromb. Haemost. , vol.84 , pp. 1087-1094
    • Rouhiainen, A.1    Imai, S.2    Rauvala, H.3    Parkkinen, J.4
  • 47
    • 0026080007 scopus 로고
    • Interactions of plasminogen and tissue plasminogen activator (t-PA) with amphoterin. Enhancement of t-PA-catalyzed plasminogen activation by amphoterin
    • Parkkinen, J., Rauvala, H. (1991) Interactions of plasminogen and tissue plasminogen activator (t-PA) with amphoterin. Enhancement of t-PA-catalyzed plasminogen activation by amphoterin. J. Biol. Chem. 266, 16730-16735.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16730-16735
    • Parkkinen, J.1    Rauvala, H.2
  • 48
    • 0027169842 scopus 로고
    • Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation
    • Parkkinen, J., Raulo, E., Merenmies, J., Nolo, R., Kajander, E. O., Baumann, M., Rauvala, H. (1993) Amphoterin, the 30-kDa protein in a family of HMG1-type polypeptides. Enhanced expression in transformed cells, leading edge localization, and interactions with plasminogen activation. J. Biol. Chem. 268, 19726-19738.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19726-19738
    • Parkkinen, J.1    Raulo, E.2    Merenmies, J.3    Nolo, R.4    Kajander, E.O.5    Baumann, M.6    Rauvala, H.7
  • 49
    • 0036775236 scopus 로고    scopus 로고
    • The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory, pathway
    • Gardella S., Andrei, C., Ferrera D., Lotti, L. V., Torrisi, M. R., Bianchi, M. E., Rubartelli, A. (2002) The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory, pathway. EMBO Rep. 3, 995-1001.
    • (2002) EMBO Rep. , vol.3 , pp. 995-1001
    • Gardella, S.1    Andrei, C.2    Ferrera, D.3    Lotti, L.V.4    Torrisi, M.R.5    Bianchi, M.E.6    Rubartelli, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.