Chromatin Remodeling: Role in Neuropathologies of the Basal Ganglia

Handbook of Behavioral Neuroscience

Volumn 20, Issue C, 2010, Pages 527-545

  Caboche, Jocelyne ^a,b,e   Roze, Emmanuel ^a,b,c   Brami Cherrier, Karen ^b,d   Betuing, Sandrine ^a,b,e  

^a INSERM   (France)

^b Université Pierre et Marie Curie   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d INSTITUT DU FER À MOULIN   (France)

^e UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84870874491     PISSN: 15697339     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-374767-9.00030-5     Document Type: Chapter

References (198)

1. Alarcon, JM, Malleret, G, Touzani, K, Vronskaya, S, Ishii, S, Kandel, ER, Barco, A, Chromatin acetylation, memory, and LTP are impaired in CBP+/– mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron 42 (2004), 947-959.
2. Alcorta, DA, Crews, CM, Sweet, LJ, Bankston, L, Jones, SW, Erikson, RL, Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase. Mol Cell Biol 9 (1989), 3850-3859.
3. Anderson, AN, Roncaroli, F, Hodges, A, Deprez, M, Turkheimer, FE, Chromosomal profiles of gene expression in Huntington's disease. Brain 131 (2008), 381-388.
4. Andersson, M, Hilbertson, A, Cenci, MA, Striatal fosB expression is causally linked with l-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease. Neurobiol Dis 6 (1999), 461-474.
5. Arthur, JS, MSK activation and physiological roles. Front Biosci 13 (2008), 5866-5879.
6. Arts, J, Angibaud, P, Marien, A, et al. R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies. Br J Cancer 97 (2007), 1344-1353.
7. Aubert, I, Guigoni, C, Hakansson, K, et al. Increased D1 dopamine receptor signaling in levodopa-induced dyskinesia. Ann Neurol 57 (2005), 17-26.
8. Bannister, AJ, Schneider, R, Myers, FA, Thorne, AW, Crane-Robinson, C, Kouzarides, T, Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes. J Biol Chem 280 (2005), 17732-17736.
9. 2+ and cAMP on transcription mediated by MEF2D and cAMP-response element-binding protein in hippocampal neurons. J Biol Chem 281 (2006), 27724-27732.
10. Berger, SL, Histone modifications in transcriptional regulation. Curr Opin Genet Dev 12 (2002), 142-148.
11. Berger, SL, The complex language of chromatin regulation during transcription. Nature 447 (2007), 407-412.
12. Berke, JD, Paletzki, RF, Aronson, GJ, Hyman, SE, Gerfen, CR, A complex program of striatal gene expression induced by dopaminergic stimulation. J Neurosci 18 (1998), 5301-5310.
13. Bertran-Gonzalez, J, Bosch, C, Maroteaux, M, Matamales, M, Herve, D, Valjent, E, Girault, JA, Opposing patterns of signaling activation in dopamine D1 and D2 receptor-expressing striatal neurons in response to cocaine and haloperidol. J Neurosci 28 (2008), 5671-5685.
14. Bibb, JA, Chen, J, Taylor, JR, et al. Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature 410 (2001), 376-380.
15. Bieliauskas, AV, Pflum, MK, Isoform-selective histone deacetylase inhibitors. Chem Soc Rev 37 (2008), 1402-1413.
16. Bolger, TA, Yao, TP, Intracellular trafficking of histone deacetylase 4 regulates neuronal cell death. J Neurosci 25 (2005), 9544-9553.
17. Bordet, R, Ridray, S, Schwartz, JC, Sokoloff, P, Involvement of the direct striatonigral pathway in levodopa-induced sensitization in 6-hydroxydopamine-lesioned rats. Eur J Neurosci 12 (2000), 2117-2123.
18. Bowers, MS, McFarland, K, Lake, RW, Peterson, YK, Lapish, CC, Gregory, ML, Lanier, SM, Kalivas, PW, Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking. Neuron 42 (2004), 269-281.
19. Brami-Cherrier, K, Lavaur, J, Pages, C, Arthur, JS, Caboche, J, Glutamate induces histone H3 phosphorylation but not acetylation in striatal neurons: role of mitogen- and stress-activated kinase-1. J Neurochem 101 (2007), 697-708.
20. Brami-Cherrier, K, Roze, E, Girault, JA, Betuing, S, Caboche, J, Role of the ERK/MSK1 signalling pathway in chromatin remodelling and brain responses to drugs of abuse. J Neurochem 108 (2009), 1323-1335.
21. Brami-Cherrier, K, Valjent, E, Herve, D, et al. Parsing molecular and behavioral effects of cocaine in mitogen- and stress-activated protein kinase-1-deficient mice. J Neurosci 25 (2005), 11444-11454.
22. Brandl, A, Heinzel, T, Kramer, OH, Histone deacetylases: salesmen and customers in the post-translational modification market. Biol Cell 101 (2009), 193-205.
23. Broide, RS, Redwine, JM, Aftahi, N, Young, W, Bloom, FE, Winrow, CJ, Distribution of histone deacetylases 1-11 in the rat brain. J Mol Neurosci 31 (2007), 47-58.
24. Brownell, JE, Allis, CD, Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation. Curr Opin Genet Dev 6 (1996), 176-184.
25. Bu, P, Evrard, YA, Lozano, G, Dent, SY, Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos. Mol Cell Biol 27 (2007), 3405-3416.
26. Candau, R, Zhou, JX, Allis, CD, Berger, SL, Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. EMBO J 16 (1997), 555-565.
27. Carlezon, WA Jr., Thome, J, Olson, VG, et al. Regulation of cocaine reward by CREB. Science 282 (1998), 2272-2275.
28. Carrozza, MJ, Kusch, T, Workman, JL, Repairing nucleosomes during transcription. Nat Struct Biol 10 (2003), 879-880.
29. Carta, AR, Tronci, E, Pinna, A, Morelli, M, Different responsiveness of striatonigral and striatopallidal neurons to L-DOPA after a subchronic intermittent L-DOPA treatment. Eur J Neurosci 21 (2005), 1196-1204.
30. Cha JH (2007) Transcriptional signatures in Huntington's disease. Prog Neurobiol.
31. Chadee, DN, Hendzel, MJ, Tylipski, CP, Allis, CD, Bazett-Jones, DP, Wright, JA, Davie, JR, Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts. J Biol Chem 274 (1999), 24914-24920.
32. Chandramohan, Y, Droste, SK, Arthur, JS, Reul, JM, The forced swimming-induced behavioral immobility response involves histone H3 phospho-acetylation and c-Fos induction in dentate gyrus granule neurons via activation of the N-methyl-D-aspartate/extracellular signal-regulated kinase/mitogen- and stress-activated kinase signalling pathway. Eur J Neurosci 27 (2008), 2701-2713.
33. Chawla, S, Hardingham, GE, Quinn, DR, Bading, H, CBP: a signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV. Science 281 (1998), 1505-1509.
34. Chawla, S, Vanhoutte, P, Arnold, FJ, Huang, CL, Bading, H, Neuronal activity-dependent nucleocytoplasmic shuttling of HDAC4 and HDAC5. J Neurochem 85 (2003), 151-159.
35. Chen, J, Kelz, MB, Hope, BT, Nakabeppu, Y, Nestler, EJ, Chronic Fos-related antigens: stable variants of deltaFosB induced in brain by chronic treatments. J Neurosci 17 (1997), 4933-4941.
36. Cheung, P, Allis, CD, Sassone-Corsi, P, Signaling to chromatin through histone modifications. Cell 103 (2000), 263-271.
37. Chrivia, JC, Kwok, RP, Lamb, N, Hagiwara, M, Montminy, MR, Goodman, RH, Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365 (1993), 855-859.
38. Chwang, WB, Arthur, JS, Schumacher, A, Sweatt, JD, The nuclear kinase mitogen- and stress-activated protein kinase 1 regulates hippocampal chromatin remodeling in memory formation. J Neurosci 27 (2007), 12732-12742.
39. Clayton, AL, Mahadevan, LC, MAP kinase-mediated phosphoacetylation of histone H3 and inducible gene regulation. FEBS Lett 546 (2003), 51-58.
40. Collins, BJ, Deak, M, Arthur, JS, Armit, LJ, Alessi, DR, In vivo role of the PIF-binding docking site of PDK1 defined by knock-in mutation. Embo J 22 (2003), 4202-4211.
41. Corbit, KC, Soh, JW, Yoshida, K, Eves, EM, Weinstein, IB, Rosner, MR, Different protein kinase C isoforms determine growth factor specificity in neuronal cells. Mol Cell Biol 20 (2000), 5392-5403.
42. Corvol, JC, Studler, JM, Schonn, JS, Girault, JA, Herve, D, Galpha(olf) is necessary for coupling D1 and A2a receptors to adenylyl cyclase in the striatum. J Neurochem 76 (2001), 1585-1588.
43. Corvol, JC, Muriel, MP, Valjent, E, Feger, J, Hanoun, N, Girault, JA, Hirsch, EC, Herve, D, Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease. J Neurosci 24 (2004), 7007-7014.
44. Cress, WD, Seto, E, Histone deacetylases, transcriptional control, and cancer. J Cell Physiol 184 (2000), 1-16.
45. Crosio, C, Heitz, E, Allis, CD, Borrelli, E, Sassone-Corsi, P, Chromatin remodeling and neuronal response: multiple signaling pathways induce specific histone H3 modifications and early gene expression in hippocampal neurons. J Cell Sci 116 (2003), 4905-4914.
46. Cuthbert, GL, Daujat, S, Snowden, AW, et al. Histone deimination antagonizes arginine methylation. Cell 118 (2004), 545-553.
47. Deak, M, Clifton, AD, Lucocq, LM, Alessi, DR, Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. Embo J 17 (1998), 4426-4441.
48. Delcuve, GP, Rastegar, M, Davie, JR, Epigenetic control. J Cell Physiol 219 (2009), 243-250.
49. Di Chiara, G, Bassareo, V, Reward system and addiction: what dopamine does and doesn't do. Curr Opin Pharmacol 7 (2007), 69-76.
50. Drummond, DC, Noble, CO, Kirpotin, DB, Guo, Z, Scott, GK, Benz, CC, Clinical development of histone deacetylase inhibitors as anticancer agents. Annu Rev Pharmacol Toxicol 45 (2005), 495-528.
51. Felsenfeld, G, Groudine, M, Controlling the double helix. Nature 421 (2003), 448-453.
52. Ferrante, RJ, Kubilus, JK, Lee, J, et al. Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. J Neurosci 23 (2003), 9418-9427.
53. Fischle, W, Wang, Y, Allis, CD, Histone and chromatin cross-talk. Curr Opin Cell Biol 15 (2003), 172-183.
54. Frodin, M, Jensen, CJ, Merienne, K, Gammeltoft, S, A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1. Embo J 19 (2000), 2924-2934.
55. Frodin, M, Antal, TL, Dummler, BA, Jensen, CJ, Deak, M, Gammeltoft, S, Biondi, RM, A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation. Embo J 21 (2002), 5396-5407.
56. Garcia-Ramirez, M, Rocchini, C, Ausio, J, Modulation of chromatin folding by histone acetylation. J Biol Chem 270 (1995), 17923-17928.
57. Gardian, G, Browne, SE, Choi, DK, et al. Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease. J Biol Chem 280 (2005), 556-563.
58. Gerfen, CR, Miyachi, S, Paletzki, R, Brown, P, D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase. J Neurosci 22 (2002), 5042-5054.
59. Giles, RH, Peters, DJ, Breuning, MH, Conjunction dysfunction: CBP/p300 in human disease. Trends Genet 14 (1998), 178-183.
60. Goodman, RH, Smolik, S, CBP/p300 in cell growth, transformation, and development. Genes Dev 14 (2000), 1553-1577.
61. Graff, J, Mansuy, IM, Epigenetic codes in cognition and behavior. Behav Brain Res 192 (2008), 70-87.
62. Graham, DL, Edwards, S, Bachtell, RK, DiLeone, RJ, Rios, M, Self, DW, Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. Nat Neurosci 10 (2007), 1029-1037.
63. Gregoretti, IV, Lee, YM, Goodson, HV, Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. J Mol Biol 338 (2004), 17-31.
64. Grewal, SI, Moazed, D, Heterochromatin and epigenetic control of gene expression. Science 301 (2003), 798-802.
65. Grimm, JW, Lu, L, Hayashi, T, Hope, BT, Su, TP, Shaham, Y, Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving. J Neurosci 23 (2003), 742-747.
66. Haggarty, SJ, Koeller, KM, Wong, JC, Grozinger, CM, Schreiber, SL, Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proc Natl Acad Sci USA 100 (2003), 4389-4394.
67. Hardingham, GE, Chawla, S, Cruzalegui, FH, Bading, H, Control of recruitment and transcription-activating function of CBP determines gene regulation by NMDA receptors and L-type calcium channels. Neuron 22 (1999), 789-798.
68. Hassa, PO, Haenni, SS, Elser, M, Hottiger, MO, Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?. Microbiol Mol Biol Rev 70 (2006), 789-829.
69. Heffron, D, Mandell, JW, Differential localization of MAPK-activated protein kinases RSK1 and MSK1 in mouse brain. Brain Res Mol Brain Res 136 (2005), 134-141.
70. Hockly, E, Richon, VM, Woodman, B, et al. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease. Proc Natl Acad Sci USA 100 (2003), 2041-2046.
71. Hodawadekar, SC, Marmorstein, R, Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design. Oncogene 26 (2007), 5528-5540.
72. Hope, BT, Nye, HE, Kelz, MB, Self, DW, Iadarola, MJ, Nakabeppu, Y, Duman, RS, Nestler, EJ, Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments. Neuron 13 (1994), 1235-1244.
73. Hsu, JY, Sun, ZW, Li, X, et al. Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102 (2000), 279-291.
74. Hu, SC, Chrivia, J, Ghosh, A, Regulation of CBP-mediated transcription by neuronal calcium signaling. Neuron 22 (1999), 799-808.
75. Huang, Y, Doherty, JJ, Dingledine, R, Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus. J Neurosci 22 (2002), 8422-8428.
76. Hubbert, C, Guardiola, A, Shao, R, et al. HDAC6 is a microtubule-associated deacetylase. Nature 417 (2002), 455-458.
77. Hyman, SE, Malenka, RC, Nestler, EJ, Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci 29 (2006), 565-598.
78. Janknecht, R, Nordheim, A, MAP kinase-dependent transcriptional coactivation by Elk-1 and its cofactor CBP. Biochem Biophys Res Commun 228 (1996), 831-837.
79. Kalivas, PW, Volkow, ND, The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry 162 (2005), 1403-1413.
80. Kelz, MB, Chen, J, Carlezon, WA Jr., et al. Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine. Nature 401 (1999), 272-276.
81. Kim, DS, Palmiter, RD, Cummins, A, Gerfen, CR, Reversal of supersensitive striatal dopamine D1 receptor signaling and extracellular signal-regulated kinase activity in dopamine-deficient mice. Neuroscience 137 (2006), 1381-1388.
82. Kim, MO, Chawla, P, Overland, RP, Xia, E, Sadri-Vakili, G, Cha, JH, Altered histone monoubiquitylation mediated by mutant huntingtin induces transcriptional dysregulation. J Neurosci 28 (2008), 3947-3957.
83. Kim, WY, Kim, S, Kim, JH, Chronic microinjection of valproic acid into the nucleus accumbens attenuates amphetamine-induced locomotor activity. Neurosci Lett 432 (2008), 54-57.
84. Konradi, C, Westin, JE, Carta, M, Eaton, ME, Kuter, K, Dekundy, A, Lundblad, M, Cenci, MA, Transcriptome analysis in a rat model of L-DOPA-induced dyskinesia. Neurobiol Dis 17 (2004), 219-236.
85. Koob, G, Kreek, MJ, Stress, dysregulation of drug reward pathways, and the transition to drug dependence. Am J Psychiatry 164 (2007), 1149-1159.
86. Korzus, E, Rosenfeld, MG, Mayford, M, CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron 42 (2004), 961-972.
87. Kouzarides, T, Histone methylation in transcriptional control. Curr Opin Genet Dev 12 (2002), 198-209.
88. Kouzarides, T, Chromatin modifications and their function. Cell 128 (2007), 693-705.
89. Kumar, A, Choi, KH, Renthal, W, et al. Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron 48 (2005), 303-314.
90. Kuo, MH, Allis, CD, Roles of histone acetyltransferases and deacetylases in gene regulation. Bioessays 20 (1998), 615-626.
91. Kuo, MH, Zhou, J, Jambeck, P, Churchill, ME, Allis, CD, Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo. Genes Dev 12 (1998), 627-639.
92. Levenson, JM, O'Riordan, KJ, Brown, KD, Trinh, MA, Molfese, DL, Sweatt, JD, Regulation of histone acetylation during memory formation in the hippocampus. J Biol Chem 279 (2004), 40545-40559.
93. Levine, AA, Guan, Z, Barco, A, Xu, S, Kandel, ER, Schwartz, JH, CREB-binding protein controls response to cocaine by acetylating histones at the fosB promoter in the mouse striatum. Proc Natl Acad Sci USA 102 (2005), 19186-19191.
94. Li, B, Carey, M, Workman, JL, The role of chromatin during transcription. Cell 128 (2007), 707-719.
95. Liu, CL, Kaplan, T, Kim, M, Buratowski, S, Schreiber, SL, Friedman, N, Rando, OJ, Single-nucleosome mapping of histone modifications in S. cerevisiae. PLoS Biol, 3, 2005, e328.
96. Lo, WS, Duggan, L, Emre, NC, Belotserkovskya, R, Lane, WS, Shiekhattar, R, Berger, SL, Snf1 – a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science 293 (2001), 1142-1146.
97. Lo, WS, Trievel, RC, Rojas, JR, Duggan, L, Hsu, JY, Allis, CD, Marmorstein, R, Berger, SL, Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell 5 (2000), 917-926.
98. Lu, J, McKinsey, TA, Zhang, CL, Olson, EN, Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases. Mol Cell 6 (2000), 233-244.
99. Lu, L, Hope, BT, Dempsey, J, Liu, SY, Bossert, JM, Shaham, Y, Central amygdala ERK signaling pathway is critical to incubation of cocaine craving. Nat Neurosci 8 (2005), 212-219.
100. Luger, K, Richmond, TJ, The histone tails of the nucleosome. Curr Opin Genet Dev 8 (1998), 140-146.
101. Marmorstein, R, Structure and function of histone acetyltransferases. Cell Mol Life Sci 58 (2001), 693-703.
102. McClung, CA, Ulery, PG, Perrotti, LI, Zachariou, V, Berton, O, Nestler, EJ, DeltaFosB: a molecular switch for long-term adaptation in the brain. Brain Res Mol Brain Res 132 (2004), 146-154.
103. McCoy, CE, Campbell, DG, Deak, M, Bloomberg, GB, Arthur, JS, MSK1 activity is controlled by multiple phosphorylation sites. Biochem J 387 (2005), 507-517.
104. McCoy, CE, Macdonald, A, Morrice, NA, Campbell, DG, Deak, M, Toth, R, McIlrath, J, Arthur, JS, Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS. Biochem J 402 (2007), 491-501.
105. McKinsey, TA, Zhang, CL, Lu, J, Olson, EN, Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature 408 (2000), 106-111.
106. McManus, KJ, Hendzel, MJ, CBP, a transcriptional coactivator and acetyltransferase. Biochem Cell Biol 79 (2001), 253-266.
107. Mehler, MF, Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol 86 (2008), 305-341.
108. Merson, TD, Dixon, MP, Collin, C, Rietze, RL, Bartlett, PF, Thomas, T, Voss, AK, The transcriptional coactivator Querkopf controls adult neurogenesis. J Neurosci 26 (2006), 11359-11370.
109. Michishita, E, Park, JY, Burneskis, JM, Barrett, JC, Horikawa, I, Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 16 (2005), 4623-4635.
110. Miller, CA, Marshall, JF, Molecular substrates for retrieval and reconsolidation of cocaine-associated contextual memory. Neuron 47 (2005), 873-884.
111. Moller, DE, Xia, CH, Tang, W, Zhu, AX, Jakubowski, M, Human rsk isoforms: cloning and characterization of tissue-specific expression. Am J Physiol 266 (1994), C351–C359.
112. Moratalla, R, Elibol, B, Vallejo, M, Graybiel, AM, Network-level changes in expression of inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal. Neuron 17 (1996), 147-156.
113. Murnion, ME, Adams, RR, Callister, DM, Allis, CD, Earnshaw, WC, Swedlow, JR, Chromatin-associated protein phosphatase 1 regulates aurora-B and histone H3 phosphorylation. J Biol Chem 276 (2001), 26656-26665.
114. Nakajima, T, Fukamizu, A, Takahashi, J, Gage, FH, Fisher, T, Blenis, J, Montminy, MR, The signal-dependent coactivator CBP is a nuclear target for pp90RSK. Cell 86 (1996), 465-474.
115. Nathan, D, Sterner, DE, Berger, SL, Histone modifications: Now summoning sumoylation. Proc Natl Acad Sci USA 100 (2003), 13118-13120.
116. Nelson, CJ, Santos-Rosa, H, Kouzarides, T, Proline isomerization of histone H3 regulates lysine methylation and gene expression. Cell 126 (2006), 905-916.
117. Nestler, EJ, Molecular basis of long-term plasticity underlying addiction. Nat Rev Neurosci 2 (2001), 119-128.
118. Nestler, EJ, Barrot, M, Self, DW, DeltaFosB: a sustained molecular switch for addiction. Proc Natl Acad Sci USA 98 (2001), 11042-11046.
119. New, L, Zhao, M, Li, Y, Bassett, WW, Feng, Y, Ludwig, S, Padova, FD, Gram, H, Han, J, Cloning and characterization of RLPK, a novel RSK-related protein kinase. J Biol Chem 274 (1999), 1026-1032.
120. Nicholas, AP, Lubin, FD, Hallett, PJ, et al. Striatal histone modifications in models of levodopa-induced dyskinesia. J Neurochem 106 (2008), 486-494.
121. Nightingale, KP, Wellinger, RE, Sogo, JM, Becker, PB, Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin. EMBO J 17 (1998), 2865-2876.
122. North, BJ, Marshall, BL, Borra, MT, Denu, JM, Verdin, E, The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol Cell 11 (2003), 437-444.
123. Nowak, SJ, Corces, VG, Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation. Trends Genet 20 (2004), 214-220.
124. Nowak, SJ, Pai, CY, Corces, VG, Protein phosphatase 2A activity affects histone H3 phosphorylation and transcription in Drosophila melanogaster. Mol Cell Biol 23 (2003), 6129-6138.
125. Nucifora, FC Jr., Sasaki, M, Peters, MF, et al. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science 291 (2001), 2423-2428.
126. Ogryzko, VV, Schiltz, RL, Russanova, V, Howard, BH, Nakatani, Y, The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87 (1996), 953-959.
127. Pallos, J, Bodai, L, Lukacsovich, T, Purcell, JM, Steffan, JS, Thompson, LM, Marsh, JL, Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease. Hum Mol Genet 17 (2008), 3767-3775.
128. Pavon, N, Martin, AB, Mendialdua, A, Moratalla, R, ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian mice. Biol Psychiatry 59 (2006), 64-74.
129. Picconi, B, Centonze, D, Hakansson, K, Bernardi, G, Greengard, P, Fisone, G, Cenci, MA, Calabresi, P, Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia. Nat Neurosci 6 (2003), 501-506.
130. Pierrat, B, Correia, JS, Mary, JL, Tomas-Zuber, M, Lesslauer, W, RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK). J Biol Chem 273 (1998), 29661-29671.
131. Putignano, E, Lonetti, G, Cancedda, L, Ratto, G, Costa, M, Maffei, L, Pizzorusso, T, Developmental downregulation of histone posttranslational modifications regulates visual cortical plasticity. Neuron 53 (2007), 747-759.
132. Radwanska, K, Valjent, E, Trzaskos, J, Caboche, J, Kaczmarek, L, Regulation of cocaine-induced activator protein 1 transcription factors by the extracellular signal-regulated kinase pathway. Neuroscience 137 (2006), 253-264.
133. Renthal, W, Nestler, EJ, Epigenetic mechanisms in drug addiction. Trends Mol Med 14 (2008), 341-350.
134. Renthal, W, Maze, I, Krishnan, V, et al. Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron 56 (2007), 517-529.
135. Robzyk, K, Recht, J, Osley, MA, Rad6-dependent ubiquitination of histone H2B in yeast. Science 287 (2000), 501-504.
136. Romieu, P, Host, L, Gobaille, S, Sandner, G, Aunis, D, Zwiller, J, Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats. J Neurosci 28 (2008), 9342-9348.
137. Rosen, JB, Chuang, E, Iadarola, MJ, Differential induction of Fos protein and a Fos-related antigen following acute and repeated cocaine administration. Brain Res Mol Brain Res 25 (1994), 168-172.
138. Roux, PP, Blenis, J, ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiol Mol Biol Rev 68 (2004), 320-344.
139. Roze, E, Saudou, F, Caboche, J, Pathophysiology of Huntington's disease: from huntingtin functions to potential treatments. Curr Opin Neurol 21 (2008), 497-503.
140. Roze, E, Betuing, S, Deyts, C, et al. Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death. FASEB J 22 (2008), 1083-1093.
141. Ryu, H, Lee, J, Hagerty, SW, Soh, BY, McAlpin, SE, Cormier, KA, Smith, KM, Ferrante, RJ, ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease. Proc Natl Acad Sci USA 103 (2006), 19176-19181.
142. Sadri-Vakili, G, Bouzou, B, Benn, CL, et al. Histones Associated with Downregulated Genes are Hypo-acetylated in Huntington's Disease Models. Hum Mol Genet 16:11 (2007), 1293-1306.
143. Santini, E, Valjent, E, Usiello, A, Carta, M, Borgkvist, A, Girault, JA, Herve, D, Greengard, P, Fisone, G, Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia. J Neurosci 27 (2009), 6995-7005.
144. Santini, E, Alcacer, C, Cacciatore, S, Heiman, M, Herve, D, Greengard, P, Girault, JA, Valjent, E, Fisone, G, L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice. J Neurochem 108 (2009), 621-633.
145. Santos-Rosa, H, Caldas, C, Chromatin modifier enzymes, the histone code and cancer. Eur J Cancer 41 (2005), 2381-2402.
146. Sassone-Corsi, P, Mizzen, CA, Cheung, P, Crosio, C, Monaco, L, Jacquot, S, Hanauer, A, Allis, CD, Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3. Science 285 (1999), 886-891.
147. Sato, T, Miura, M, Yamada, M, et al. Severe neurological phenotypes of Q129 DRPLA transgenic mice serendipitously created by en masse expansion of CAG repeats in Q76 DRPLA mice. Hum Mol Genet 18 (2009), 723-736.
148. Schroeder, FA, Lin, CL, Crusio, WE, Akbarian, S, Antidepressant-like effects of the histone deacetylase inhibitor, sodium butyrate, in the mouse. Biol Psychiatry 62:1 (1999), 55-64 Jul 1.
149. Shaywitz, AJ, Greenberg, ME, CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annu Rev Biochem 68 (1999), 821-861.
150. Shiio, Y, Eisenman, RN, Histone sumoylation is associated with transcriptional repression. Proc Natl Acad Sci USA 100 (2003), 13225-13230.
151. Shilatifard, A, Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu Rev Biochem 75 (2006), 243-269.
152. Shimohata, M, Shimohata, T, Igarashi, S, Naruse, S, Tsuji, S, Interference of CREB-dependent transcriptional activation by expanded polyglutamine stretches – augmentation of transcriptional activation as a potential therapeutic strategy for polyglutamine diseases. J Neurochem 93 (2005), 654-663.
153. Shimohata, T, et al. Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription. Nat Genet 26 (2000), 29-36.
154. 2+-stimulated adenylyl cyclases regulate ERK-dependent activation of MSK1 during fear conditioning. Neuron 53:1 (2007), 79-89 Jan 4.
155. Smith, JA, Poteet-Smith, CE, Malarkey, K, Sturgill, TW, Identification of an extracellular signal-regulated kinase (ERK) docking site in ribosomal S6 kinase, a sequence critical for activation by ERK in vivo. J Biol Chem 274 (1999), 2893-2898.
156. Sng, JC, Taniura, H, Yoneda, Y, Histone modifications in kainate-induced status epilepticus. Eur J Neurosci 23 (2006), 1269-1282.
157. Soloaga, A, Thomson, S, Wiggin, GR, Rampersaud, N, Dyson, MH, Hazzalin, CA, Mahadevan, LC, Arthur, JS, MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14. Embo J 22 (2003), 2788-2797.
158. Spanagel, R, Herz, A, Shippenberg, TS, Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proc Natl Acad Sci USA 89 (1992), 2046-2050.
159. Stack, EC, Del Signore, SJ, Luthi-Carter, R, et al. Modulation of Nucleosome Dynamics in Huntington's Disease. Hum Mol Genet 16:10 (2007), 1164-1175.
160. Steffan, JS, Bodai, L, Pallos, J, et al. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature 413 (2001), 739-743.
161. Steiner, H, Gerfen, CR, Cocaine-induced c-fos messenger RNA is inversely related to dynorphin expression in striatum. J Neurosci 13 (1993), 5066-5081.
162. Sterner, DE, Berger, SL, Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 64 (2000), 435-459.
163. Stipanovich, A, Valjent, E, Matamales, M, et al. A phosphatase cascade by which rewarding stimuli control nucleosomal response. Nature 453 (2008), 879-884.
164. Strahl, BD, Allis, CD, The language of covalent histone modifications. Nature 403 (2000), 41-45.
165. Sugiyama, K, Sugiura, K, Hara, T, Sugimoto, K, Shima, H, Honda, K, Furukawa, K, Yamashita, S, Urano, T, Aurora-B associated protein phosphatases as negative regulators of kinase activation. Oncogene 21 (2002), 3103-3111.
166. Thomas, EA, Coppola, G, Desplats, PA, et al. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice. Proc Natl Acad Sci USA 105 (2008), 15564-15569.
167. Thomas, T, Voss, AK, Chowdhury, K, Gruss, P, Querkopf, a MYST family histone acetyltransferase, is required for normal cerebral cortex development. Development 127 (2000), 2537-2548.
168. Thomson, S, Clayton, AL, Mahadevan, LC, Independent dynamic regulation of histone phosphorylation and acetylation during immediate-early gene induction. Mol Cell 8 (2001), 1231-1241.
169. Thomson, S, Clayton, AL, Hazzalin, CA, Rose, S, Barratt, MJ, Mahadevan, LC, The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase. Embo J 18 (1999), 4779-4793.
170. Tsankova, NM, Kumar, A, Nestler, EJ, Histone modifications at gene promoter regions in rat hippocampus after acute and chronic electroconvulsive seizures. J Neurosci 24 (2004), 5603-5610.
171. Tse, C, Fletcher, TM, Hansen, JC, Enhanced transcription factor access to arrays of histone H3/H4 tetramer. DNA complexes in vitro: implications for replication and transcription. Proc Natl Acad Sci USA 95 (1998), 12169-12173.
172. Tse, C, Sera, T, Wolffe, AP, Hansen, JC, Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III. Mol Cell Biol 18 (1998), 4629-4638.
173. Ura, K, Kurumizaka, H, Dimitrov, S, Almouzni, G, Wolffe, AP, Histone acetylation: influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression. EMBO J 16 (1997), 2096-2107.
174. Valjent, E, Corvol, JC, Trzaskos, JM, Girault, JA, Herve, D, Role of the ERK pathway in psychostimulant-induced locomotor sensitization. BMC Neurosci, 7, 2006, 20.
175. Valjent, E, Corvol, JC, Pages, C, Besson, MJ, Maldonado, R, Caboche, J, Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties. J Neurosci 20 (2000), 8701-8709.
176. Valjent, E, Aubier, B, Corbille, AG, Brami-Cherrier, K, Caboche, J, Topilko, P, Girault, JA, Herve, D, Plasticity-associated gene Krox24/Zif268 is required for long-lasting behavioral effects of cocaine. J Neurosci 26 (2006), 4956-4960.
177. Valjent, E, Pascoli, V, Svenningsson, P, et al. Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proc Natl Acad Sci USA 102 (2005), 491-496.
178. Vecsey, CG, Hawk, JD, Lattal, KM, et al. Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. J Neurosci 27 (2007), 6128-6140.
179. Wang, L, Liu, L, Berger, SL, Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo. Genes Dev 12 (1998), 640-653.
180. Weaver, IC, Cervoni, N, Champagne, FA, D'Alessio, AC, Sharma, S, Seckl, JR, Dymov, S, Szyf, M, Meaney, MJ, Epigenetic programming by maternal behavior. Nat Neurosci 7 (2004), 847-854.
181. Westin JE, Vercammen L, Strome EM, Konradi C, Cenci MA (2007) Spatiotemporal Pattern of Striatal ERK1/2 Phosphorylation in a Rat Model of L-DOPA-Induced Dyskinesia and the Role of Dopamine D1 Receptors. Biol Psychiatry.
182. Wiggin, GR, Soloaga, A, Foster, JM, Murray-Tait, V, Cohen, P, Arthur, JS, MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts. Mol Cell Biol 22 (2002), 2871-2881.
183. Williams, MR, Arthur, JS, Balendran, A, van der Kaay, J, Poli, V, Cohen, P, Alessi, DR, The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells. Curr Biol 10 (2000), 439-448.
184. Wood, JD, Nucifora, FC Jr., Duan, K, Zhang, C, Wang, J, Kim, Y, Schilling, G, Sacchi, N, Liu, JM, Ross, CA, Atrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcription. J Cell Biol 150 (2000), 939-948.
185. Yamauchi, T, Yamauchi, J, Kuwata, T, et al. Distinct but overlapping roles of histone acetylase PCAF and of the closely related PCAF-B/GCN5 in mouse embryogenesis. Proc Natl Acad Sci USA 97 (2000), 11303-11306.
186. Yang, L, Mei, Q, Zielinska-Kwiatkowska, A, et al. An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B. Biochem J 369 (2003), 651-657.
187. Yao, TP, Oh, SP, Fuchs, M, et al. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell 93 (1998), 361-372.
188. Ying, M, Xu, R, Wu, X, Zhu, H, Zhuang, Y, Han, M, Xu, T, Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA. J Biol Chem 281 (2006), 12580-12586.
189. You, A, Tong, JK, Grozinger, CM, Schreiber, SL, CoREST is an integral component of the CoREST- human histone deacetylase complex. Proc Natl Acad Sci USA 98 (2001), 1454-1458.
190. Zeniou, M, Ding, T, Trivier, E, Hanauer, A, Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning. Hum Mol Genet 11 (2002), 2929-2940.
191. Zhang, J, Zhang, D, McQuade, JS, Behbehani, M, Tsien, JZ, Xu, M, c-fos regulates neuronal excitability and survival. Nat Genet 30 (2006), 416-420.
192. Zhang, J, Zhang, L, Jiao, H, Zhang, Q, Zhang, D, Lou, D, Katz, JL, Xu, M, c-Fos facilitates the acquisition and extinction of cocaine-induced persistent changes. J Neurosci 26 (2006), 13287-13296.
193. Zhang, D, Zhang, L, Lou, DW, Nakabeppu, Y, Zhang, J, Xu, M, c-fos regulates neuronal excitability and survival. J Neurochem 82:6 (2002), 1453-1464 Sep.
194. Zhang, S, Xu, L, Lee, J, Xu, T, Drosophila atrophin homolog functions as a transcriptional corepressor in multiple developmental processes. Cell 108 (2002), 45-56.
195. Zhang, Y, Reinberg, D, Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev 15 (2001), 2343-2360.
196. Zhao, Y, Bjorbaek, C, Moller, DE, Regulation and interaction of pp90(rsk) isoforms with mitogen-activated protein kinases. J Biol Chem 271 (1996), 29773-29779.
197. Zhuang, X, Belluscio, L, Hen, R, G(olf)alpha mediates dopamine D1 receptor signaling. J Neurosci, 20, 2000, RC91.
198. Zoltewicz, JS, Stewart, NJ, Leung, R, Peterson, AS, Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development 131 (2004), 3-14.