Independent dynamic regulation of histone phosphorylation and acetylation during immediate-early gene induction

Molecular Cell

Volumn 8, Issue 6, 2001, Pages 1231-1241

  Thomson, Stuart ^a   Clayton, Alison L ^a   Mahadevan, Louis C ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE H3; HISTONE H4; MITOGEN ACTIVATED PROTEIN KINASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN C FOS; STRESS ACTIVATED PROTEIN KINASE;

ACETYLATION; ANIMAL CELL; ARTICLE; CHROMATIN; CONTROLLED STUDY; ENZYME ACTIVITY; GENE INDUCTION; GENETIC TRANSCRIPTION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NUCLEOSOME; ONCOGENE C FOS; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0035694785     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00404-X     Document Type: Article

References (60)

1. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-β promoter
2. Activation of SRF-regulated chromosomal templates by Rho-family GTPases requires a signal that also induces H4 hyperacetylation
3. Affinity chromatographic purification of nucleosomes containing transcriptionally active DNA sequences
4. MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells
5. NF-κB: Ten years after
6. The CBP co-activator is a histone acetyltransferase
7. dSIR2 and dHDAC6: Two novel, inhibitor-resistant deacetylases in Drosophila melanogaster
8. Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction
9. Tetrahymena histone acetyltransferase A: A homolog to yeast Gcn5p linking histone acetylation to gene activation
10. Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity
11. Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts
12. Regulation of hormone induced histone hyperacetylation and gene activation via acetylation of an acetylase
13. Rapid and reversible changes in nucleosome structure accompany the activation, repression, and superinduction of murine fibroblast protooncogenes c-fos and c-myc
14. Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation
15. Phosphoacetylation of histone H3 on c-fos and c-jun-associated nucleosomes upon gene activation
16. The search for physiological substrates of MAP and SAP kinases in mammalian cells
17. Ordered recruitment of transcription and chromatin remodelling factors to a cell cycle and developmentally regulated promoter
18. STATs and gene regulation
19. Specificity and mechanism of action of some commonly used protein kinase inhibitors
20. Mitogen- and stress- activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB
21. Acetyllysine-binding and function of bromodomain containing proteins in chromatin
22. Histone acetylation beyond promoters: Long range acetylation patterns in the chromatin world
23. Developmentally dynamic histone acetylation pattern of a tissue specific chromatin domain
24. The human histone deacetylase family
25. p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient
26. Core histone hyperacetylation co-maps with generalized DNase-I sensitivity in the chicken β-globin chromosomal domain
27. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deactylase
28. ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation
29. Cell cycle regulated histone acetylation required for expression of the yeast HO gene
30. Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo
31. Gcn4 activator targets Gcn5 histone acetyltransferase to specific promoters independently of transcription
32. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
33. Orchestrated response: A symphony of transcription factors for gene control
34. Transitions in histone acetylation reveal boundaries of three separately regulated neighbouring loci
35. Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14
36. Snf1 - A histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription
37. Rapid histone H3 phosphorylation in response to growth-factors, phorbol esters, okadaic acid, and protein-synthesis inhibitors
38. Protein modules that manipulate histone tails for chromatin regulation
39. Targeted and extended acetylation of histones H4 and H3 at active and inactive genes in chicken embryo erthrocytes
40. Phosphorylation of histone H3 correlates with transcriptionally active loci
41. The transcriptional coactivators p300 and CBP are histone acetyltransferases
42. Histone H4 acetylation distinguishes coding regions of the human genome from heterochromatin in a differentiation-dependent but transcription-independent manner
43. Follicle stimulating hormone stimulates protein kinase A mediated histone H3 phosphorylation and acetylation leading to select gene activation in ovarian granulosa cells
44. Requirements of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3
45. Steroid receptor coactivator-1 is a histone acetyltransferase
46. The language of covalent histone modifications
47. Histone acetylation and transcriptional regulatory mechanisms
48. Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin
49. MAP kinase-mediated signalling to nucleosomes and immediate-early gene induction
50. The nucleosomal response associated with immediate early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase
51. Regulation of transcription by MAP kinase cascades
52. Mutations in the kinase RSK2 associated with Coffin-Lowry syndrome
53. Decoding the nucleosome
54. ATP-dependent chromatin-remodelling complexes
55. Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexes
56. Global histone acetylation and deacetylation in yeast
57. Steady-state levels of histone acetylation in Saccharomyces cerivisiae
58. Alteration of nucleosome structure as a mechanism of transcriptional regulation
59. Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1
60. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A