CBP: A signal-regulated transcriptional coactivator controlled by nuclear calcium and CaM kinase IV

Science

Volumn 281, Issue 5382, 1998, Pages 1505-1509

  Chawla, Sangeeta ^a   Hardingham, Giles E ^a   Quinn, David R ^a,b   Bading, Hilmar ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN);

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; GENE EXPRESSION REGULATION; HYPOPHYSIS CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM CHANNELS; CELL LINE; CELL NUCLEUS; CREB-BINDING PROTEIN; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOPLASM; GENES, REPORTER; MICE; MODELS, GENETIC; NUCLEAR PROTEINS; PHOSPHORYLATION; PHOSPHOSERINE; RAS PROTEINS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0032483380     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.281.5382.1505     Document Type: Article

References (48)

1. J. C. Chrivia et al., Nature 365, 855 (1993).
2. J. R. Lundblad, R. P. S. Kwok, M. E. Laurance, M. L. Harter, R. H. Goodman, ibid. 374, 85 (1995); P. S. Goldman, V. K. Tran, R. H. Goodman, Recent Prog. Horm. Res. 52, 103 (1997); R. Janknecht and T. Hunter, Curr. Biol. 6, 951 (1996).
3. J. R. Lundblad, R. P. S. Kwok, M. E. Laurance, M. L. Harter, R. H. Goodman, ibid. 374, 85 (1995); P. S. Goldman, V. K. Tran, R. H. Goodman, Recent Prog. Horm. Res. 52, 103 (1997); R. Janknecht and T. Hunter, Curr. Biol. 6, 951 (1996).
4. J. R. Lundblad, R. P. S. Kwok, M. E. Laurance, M. L. Harter, R. H. Goodman, ibid. 374, 85 (1995); P. S. Goldman, V. K. Tran, R. H. Goodman, Recent Prog. Horm. Res. 52, 103 (1997); R. Janknecht and T. Hunter, Curr. Biol. 6, 951 (1996).
5. R. P. S. Kwok et al., Nature 370, 223 (1994).
6. B. L. Kee, J. Arias, M. R. Montminy, J. Biol. Chem. 271, 2373 (1996); T. Nakajima, C. Uchida, S. F. Anderson, J. D. Pardin, M. Montminy, Genes Dev. 11, 738 (1997).
7. B. L. Kee, J. Arias, M. R. Montminy, J. Biol. Chem. 271, 2373 (1996); T. Nakajima, C. Uchida, S. F. Anderson, J. D. Pardin, M. Montminy, Genes Dev. 11, 738 (1997).
8. V. V. Ogryzko, R. L. Schiltz, V. Russanova, B. H. Howard, Y. Nakatani, Cell 87, 953 (1996); A. J. Bannister and T. Kouzarides, Nature 384, 641 (1996); X. J. Yang, V. V. Ogryzko, J. Nishikawa, B. H. Howard, Y. Nakatani, ibid. 382, 319 (1996).
9. V. V. Ogryzko, R. L. Schiltz, V. Russanova, B. H. Howard, Y. Nakatani, Cell 87, 953 (1996); A. J. Bannister and T. Kouzarides, Nature 384, 641 (1996); X. J. Yang, V. V. Ogryzko, J. Nishikawa, B. H. Howard, Y. Nakatani, ibid. 382, 319 (1996).
10. V. V. Ogryzko, R. L. Schiltz, V. Russanova, B. H. Howard, Y. Nakatani, Cell 87, 953 (1996); A. J. Bannister and T. Kouzarides, Nature 384, 641 (1996); X. J. Yang, V. V. Ogryzko, J. Nishikawa, B. H. Howard, Y. Nakatani, ibid. 382, 319 (1996).
11. J. Arias et al., Nature 370, 226 (1994).
12. D. Chakravarti et al., ibid. 383, 99 (1996); R. Janknecht and A. Nordheim, Oncogene 12, 1961 (1996); S. Bhattacharya et al., Nature 383, 344 (1996); Y. Kamei et al., Cell 85, 403 (1996); W. Yuan, G. Condorelli, M. Caruso, A. Felsani, A. Giordani, J. Biol. Chem. 271, 9009 (1996).
13. D. Chakravarti et al., ibid. 383, 99 (1996); R. Janknecht and A. Nordheim, Oncogene 12, 1961 (1996); S. Bhattacharya et al., Nature 383, 344 (1996); Y. Kamei et al., Cell 85, 403 (1996); W. Yuan, G. Condorelli, M. Caruso, A. Felsani, A. Giordani, J. Biol. Chem. 271, 9009 (1996).
14. D. Chakravarti et al., ibid. 383, 99 (1996); R. Janknecht and A. Nordheim, Oncogene 12, 1961 (1996); S. Bhattacharya et al., Nature 383, 344 (1996); Y. Kamei et al., Cell 85, 403 (1996); W. Yuan, G. Condorelli, M. Caruso, A. Felsani, A. Giordani, J. Biol. Chem. 271, 9009 (1996).
15. D. Chakravarti et al., ibid. 383, 99 (1996); R. Janknecht and A. Nordheim, Oncogene 12, 1961 (1996); S. Bhattacharya et al., Nature 383, 344 (1996); Y. Kamei et al., Cell 85, 403 (1996); W. Yuan, G. Condorelli, M. Caruso, A. Felsani, A. Giordani, J. Biol. Chem. 271, 9009 (1996).
16. D. Chakravarti et al., ibid. 383, 99 (1996); R. Janknecht and A. Nordheim, Oncogene 12, 1961 (1996); S. Bhattacharya et al., Nature 383, 344 (1996); Y. Kamei et al., Cell 85, 403 (1996); W. Yuan, G. Condorelli, M. Caruso, A. Felsani, A. Giordani, J. Biol. Chem. 271, 9009 (1996).
17. A. J. Bannister and T. Kouzarides, EMBO J. 14, 4758 (1995); A. J. Bannister, T. Oehler, D. Wilhelm, P. Angel, T. Kouzarides, Oncogene 11, 2509 (1995).
18. A. J. Bannister and T. Kouzarides, EMBO J. 14, 4758 (1995); A. J. Bannister, T. Oehler, D. Wilhelm, P. Angel, T. Kouzarides, Oncogene 11, 2509 (1995).
19. D. Parker et al., Mol. Cell. Biol. 16, 694 (1996).
20. 133 and GAL4-CREB-mediated gene expression was done 7 min and 2 hours after stimulation, respectively.
21. G. E. Hardingham, S. Chawla, C. M. Johnson, H. Bading, Nature 385, 260 (1997).
22. P. Sun, H. Enslen, P. S. Myung, R. A. Maurer, Genes Dev. 8, 2527 (1994).
23. J. I. Morgan and T. Curran, Annu. Rev. Neurosci. 14, 421 (1991); A. Ghosh and M. E. Greenberg, Science 268, 239 (1995); H. Bito, K. Deisseroth, R. W. Tsien, Curr. Opin. Neurobiol. 7, 419 (1997); H. Bading, G. E. Hardingham, C. M. Johnson, S. Chawla, Biochem. Biophys. Res. Commun. 236, 541 (1997).
24. J. I. Morgan and T. Curran, Annu. Rev. Neurosci. 14, 421 (1991); A. Ghosh and M. E. Greenberg, Science 268, 239 (1995); H. Bito, K. Deisseroth, R. W. Tsien, Curr. Opin. Neurobiol. 7, 419 (1997); H. Bading, G. E. Hardingham, C. M. Johnson, S. Chawla, Biochem. Biophys. Res. Commun. 236, 541 (1997).
25. J. I. Morgan and T. Curran, Annu. Rev. Neurosci. 14, 421 (1991); A. Ghosh and M. E. Greenberg, Science 268, 239 (1995); H. Bito, K. Deisseroth, R. W. Tsien, Curr. Opin. Neurobiol. 7, 419 (1997); H. Bading, G. E. Hardingham, C. M. Johnson, S. Chawla, Biochem. Biophys. Res. Commun. 236, 541 (1997).
26. J. I. Morgan and T. Curran, Annu. Rev. Neurosci. 14, 421 (1991); A. Ghosh and M. E. Greenberg, Science 268, 239 (1995); H. Bito, K. Deisseroth, R. W. Tsien, Curr. Opin. Neurobiol. 7, 419 (1997); H. Bading, G. E. Hardingham, C. M. Johnson, S. Chawla, Biochem. Biophys. Res. Commun. 236, 541 (1997).
27. M. Sheng, M. A. Thompson, M. E. Greenberg, Science 252, 1427 (1991).
28. H. Bading, D. D. Ginty, M. E. Greenberg, ibid. 260, 181 (1993).
29. K. F. Jensen, C.-A. Ohmstede, R. S. Fisher, N. Sayhoun, Proc. Natl. Acad. Sci. U.S.A. 88, 2850 (1991).
30. 133, analyzed immunocytochemically 7 min after KCl-FPL stimulation, in cells microinjected with the expression vector for the negative interfering mutant of CaM kinase IV was 100% ± 5% (58 cells) of that obtained in surrounding uninjected cells (220 cells analyzed).
31. H. Bading and M. E. Greenberg, Science 253, 912 (1991); L. B. Rosen, D. D. Ginty, M. J. Weber, M. E. Greenberg, Neuron 12, 1207 (1994); G. Rusanescu, H. Qi, S. M. Thomas, J. S. Brugge, S. Halegoua, ibid. 15, 1415 (1995).
32. H. Bading and M. E. Greenberg, Science 253, 912 (1991); L. B. Rosen, D. D. Ginty, M. J. Weber, M. E. Greenberg, Neuron 12, 1207 (1994); G. Rusanescu, H. Qi, S. M. Thomas, J. S. Brugge, S. Halegoua, ibid. 15, 1415 (1995).
33. H. Bading and M. E. Greenberg, Science 253, 912 (1991); L. B. Rosen, D. D. Ginty, M. J. Weber, M. E. Greenberg, Neuron 12, 1207 (1994); G. Rusanescu, H. Qi, S. M. Thomas, J. S. Brugge, S. Halegoua, ibid. 15, 1415 (1995).
34. C. S. Hill, J. Wynne, R. Treisman, Cell 81, 1159 (1995).
35. T. Nakajima et al., ibid. 86, 465 (1996).
36. R. Eckner et al., Genes Dev. 8, 869 (1994); Z. Arany, D. Newsome, E. Oldread, D. M. Livingston, R. Eckner, Nature 374, 81 (1995).
37. R. Eckner et al., Genes Dev. 8, 869 (1994); Z. Arany, D. Newsome, E. Oldread, D. M. Livingston, R. Eckner, Nature 374, 81 (1995).
38. c expression vectors, cells were stimulated; they were processed for immunocytochemical analysis of pF222ΔCREmyc expression after an additional 2 hours.
39. 2-TATA-CAT (chloramphenicol acetyltransferase) reporter gene (19).
40. R. Marais, J. Wynne, R. Treisman, Cell 73, 381 (1993); R. Janknecht, W. H. Ernst, V. Pingoud, A. Nordheim, EMBO J 12, 5097 (1993); G. Gille, A. D. Sharrocks, P. E. Shaw, Nature 358, 414 (1992).
41. R. Marais, J. Wynne, R. Treisman, Cell 73, 381 (1993); R. Janknecht, W. H. Ernst, V. Pingoud, A. Nordheim, EMBO J 12, 5097 (1993); G. Gille, A. D. Sharrocks, P. E. Shaw, Nature 358, 414 (1992).
42. R. Marais, J. Wynne, R. Treisman, Cell 73, 381 (1993); R. Janknecht, W. H. Ernst, V. Pingoud, A. Nordheim, EMBO J 12, 5097 (1993); G. Gille, A. D. Sharrocks, P. E. Shaw, Nature 358, 414 (1992).
43. C. M. Johnson, C. S. Hill, S. Chawla, R. Treisman, H. Bading, J. Neurosci. 17, 6189 (1997).
44. S. Chawla, G. E. Hardingham, D. R. Quinn, H. Bading, unpublished observation.
45. D. D. Ginty, A. Bonni, M. E. Greenberg, Cell 77, 713 (1994).
46. M. Sheng, S. T. Dougan, G. McFadden, M. E. Greenberg, Mol. Cell. Biol. 8, 2787 (1988).
47. J. Xing, D. D. Ginty, M. E. Greenberg, Science 273, 959 (1996).
48. We thank D. D. Ginty for the phosphorylated CREB antibody; R. Eckner, M. E. Greenberg, T. Kouzarides, R. A. Maurer, A. R. Means, and R. Treisman for plasmids; and W. Wisden for discussion and comments on the manuscript. Supported by the Medical Research Council, GlaxoWellcome, the Epilepsy Research Foundation, and SmithKline Beecham.