Differentiated treatment protocols for high- and standard-risk hepatoblastoma - An interim report of the German liver tumor study HB 99;Differenzierte therapieansätze für hoch- und standardrisiko-hepatoblastome - Ein zwischenbericht der multizentrischen studie HB 99 der GPOH

Klinische Padiatrie

Volumn 215, Issue 3, 2003, Pages 159-165

  Haberle B ^a   Bode, U ^b   Von Schweinitz, D ^a  

^a UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Hepatoblastoma; High dose chemotherapy; Surgery

Indexed keywords

AMINOTRANSFERASE; CARBOPLATIN; CISPLATIN; DOXORUBICIN; ETOPOSIDE; IFOSFAMIDE;

ADOLESCENT; ADVANCED CANCER; ARTICLE; AUDIOMETRY; CANCER CHEMOTHERAPY; CANCER INVASION; CANCER REGRESSION; CANCER RISK; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CHILD; CLINICAL ARTICLE; CLINICAL PROTOCOL; COMPUTER ASSISTED TOMOGRAPHY; CREATININE CLEARANCE; DISEASE SEVERITY; DISEASE TRANSMISSION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MEGADOSE; FATIGUE; FEMALE; FOLLOW UP; GERMANY; HEPATOBLASTOMA; HUMAN; INFANT; INFECTION; LEUKOPENIA; LIVER FUNCTION; LIVER TRANSPLANTATION; LIVER TUMOR; LUNG TOXICITY; MALE; METASTASIS; MUCOSA INFLAMMATION; PROGNOSIS; STANDARD; THROMBOCYTOPENIA; VOMITING;

ADOLESCENT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARBOPLATIN; CHEMOTHERAPY, ADJUVANT; CHILD; CHILD, PRESCHOOL; CISPLATIN; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; ETOPOSIDE; FEMALE; FOLLOW-UP STUDIES; HEPATOBLASTOMA; HUMANS; INFANT; LIVER NEOPLASMS; MALE; NEOADJUVANT THERAPY; NEOPLASM INVASIVENESS; NEOPLASM STAGING;

EID: 0038796909     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-39375     Document Type: Article

References (12)

1. Brown J, Perilongo G, Shafford E, Keeling J, Pritchard J, Brock P, Dicks-Miraux C, Phillips A, Vos A, Plaschkes J. Pretreatment prognostic factors for children with hepatoblastoma - Results from the International Society of Pediatric Oncology (SIOP) study SIOPEL-1. Eur J Cancer 2000; 36: 1418-1425
2. Exelby PR, Filler RM, Grosfeld JL. Liver tumors in children in the particular reference to hepatoblastoma and hepatocellular carcinoma: American Academy of Pediatrics Surgical Section Survey-1974. J Pediatr Surg 1975; 10: 329-337
3. Feusner JH, Krailo MD, Haas JE, Campbell JR, Lloyd DA, Ablin AR. Treatment of pulmonary metastases of initial stage I hepatoblastoma in childhood. Cancer 1993; 71: 859-864
4. Fuchs J, Rydzynski J, von Schweinitz D, Bode U, Hecker H, Weinel P, Bürger D, Harms D, Erttmann R, Oldhafer K, Mildenberger H. Pretreatment prognostic factors and treatment results in children with hepatoblastoma. Report from the German Cooperative Pediatric Liver Tumor Study HB 94. Cancer 2002; 1: 172-182
5. Kaatsch P, Spix C, Michaelis J. 20 Jahre Deutsches Kinderkrebsregister, Jahresbericht 2002. Mainz: Johannes-Gutenberg-Universität, 2002: 84-85
6. Katzenstein HM, London WB, Douglass EC, Reynolds M, Plaschkes J, Finegold MJ, Bowman LC. Treatment of unresectable and metastatic hepatoblastoma: a Pediatric Oncology Group phase II study. J Clin Oncol 2002; 20: 3438-3444
7. Ortega JA, Douglass EC, Feusner JH, Reynolds M, Querin JJ, Finegold MJ, Haas JE, King DR, Liu-Mares W, Sensel MG, Krailo MD. Randomized comparison of cisplatin/vincristin/fluorouracil and cisplatin/continuous infusion doxorubicin for treatment of pediatric hepatoblastoma: a report from the Children's Cancer Group and the Pediatric Oncology Group. J Clin Oncol 2000; 18: 2665-2675
8. Perilongo G, Brown J, Shafford E, Brock P, de Camargo B, Keeling JW, Vos A, Phillips A, Pritchard J, Plaschkes J. Hepatoblastoma presenting with lung metastasis. Cancer 2000; 89: 1845-1853
9. Pritchard J, Brown J, Shafford E, Perilongo G, Brock P, Dicks-Mireaux C, Keeling J, Phillips A, Vos A, Plaschkes J. Cisplatin, doxorubicin and delayed surgery for childhood hepatoblastoma is a successful approach. Results of the first prospective study of the International Society of Pediatric Oncology (SIOP) - SIOPEL 1. J Clin Oncol 2000; 18: 3819-3828
10. Reyes JD, Carr B, Dvorchik I, Kokoskis S, Jaffe R, Gerber D, Mazaiegos GV, Bueno J, Selby R. Liver transplantation and chemotherapy for hepatoblastoma and hepatocellular cancer in childhood and adolescence. J Pediatr 2000; 136: 795-804
11. von Schweinitz D, Byrd DJ, Hecker H, Weinel P, Bode U, Bürger D, Erttmann R, Harms D, Mildenberger H. Efficiency and toxicity of ifosfamide, cisplatin and doxorubicin in the treatment of childhood hepatoblastoma. Eur J Cancer 1997; 33: 1243-1249
12. Weinberg AG, Finegold MF. Primary hepatic tumors of childhood. Hum Pathol 1983; 14: 512-537