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Volumn 10, Issue 3, 2012, Pages 239-253

The wnt pathway in mood disorders

Author keywords

Antidepressant Drugs; Antipsychotic Drugs; Bipolar Disorder; Major Depression; Mood Disorders; Mood Stabilising Agents; Wingless (Wnt) signalling

Indexed keywords

ANTIDEPRESSANT AGENT; CARBAMAZEPINE; CLOZAPINE; GLYCOGEN SYNTHASE KINASE; GLYCOGEN SYNTHASE KINASE 3; HALOPERIDOL; LAMOTRIGINE; LITHIUM; OLANZAPINE; QUETIAPINE; RISPERIDONE; VALPROIC ACID; ZIPRASIDONE;

EID: 84867564968     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/157015912803217279     Document Type: Article
Times cited : (48)

References (183)
  • 1
    • 0025729647 scopus 로고
    • The segment polarity gene armadillo interacts with the wingless signalling pathway in both embryonic and adult pattern formation
    • Peifer, M.; Rauskolb, C.; Williams, M.; Riggleman, B.; Wieschaus, E. The segment polarity gene armadillo interacts with the wingless signalling pathway in both embryonic and adult pattern formation. Development, 1991, 111, 1029-1043.
    • (1991) Development , vol.111 , pp. 1029-1043
    • Peifer, M.1    Rauskolb, C.2    Williams, M.3    Riggleman, B.4    Wieschaus, E.5
  • 2
    • 20944435474 scopus 로고    scopus 로고
    • Wnt signalling: Multiple functions in neural development
    • Ille, F.; Sommer, L. Wnt signalling: multiple functions in neural development. Cell. Mol. Life Sci., 2005, 62, 1100-1108.
    • (2005) Cell. Mol. Life Sci , vol.62 , pp. 1100-1108
    • Ille, F.1    Sommer, L.2
  • 3
    • 77956675524 scopus 로고    scopus 로고
    • Intracellular signalling pathways and mood disorders
    • Fišar, Z.; Hroudová, J. Intracellular signalling pathways and mood disorders. Folia Biol (Praha), 2010, 56, 135-148.
    • (2010) Folia Biol (Praha) , vol.56 , pp. 135-148
    • Fišar, Z.1    Hroudová, J.2
  • 4
    • 33845350346 scopus 로고    scopus 로고
    • The ups and downs of Wnt signalling in prevalent neurological disorders
    • De Ferrari, G. V.; Moon, R. T. The ups and downs of Wnt signalling in prevalent neurological disorders. Oncogene, 2006, 25, 7545-7553.
    • (2006) Oncogene , vol.25 , pp. 7545-7553
    • de Ferrari, G.V.1    Moon, R.T.2
  • 6
    • 0033609561 scopus 로고    scopus 로고
    • Increased expression of Wnt-1 in schizophrenic brains
    • Miyaoka, T.; Seno, H.; Ishino, H. Increased expression of Wnt-1 in schizophrenic brains. Schizophr. Res., 1999, 38, 1-6.
    • (1999) Schizophr. Res , vol.38 , pp. 1-6
    • Miyaoka, T.1    Seno, H.2    Ishino, H.3
  • 7
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein, PS.; Melton, D. A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. U. S. A., 1996, 93, 8455-8459.
    • (1996) Proc. Natl. Acad. Sci. U. S. A , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 8
    • 0031149476 scopus 로고    scopus 로고
    • Activation of the Wnt signalling pathway: A molecular mechanism for lithium action
    • Hedgepeth, C. M.; Conrad, L. J.; Zhang, J.; Huang, H. C.; Lee, V. M.; Klein, P. S. Activation of the Wnt signalling pathway: a molecular mechanism for lithium action. Dev. Biol., 1997, 185, 82-91.
    • (1997) Dev. Biol , vol.185 , pp. 82-91
    • Hedgepeth, C.M.1    Conrad, L.J.2    Zhang, J.3    Huang, H.C.4    Lee, V.M.5    Klein, P.S.6
  • 9
    • 0034987265 scopus 로고    scopus 로고
    • Lithium-related genetics of bipolar disorder
    • Detera-Wadleigh, S. D. Lithium-related genetics of bipolar disorder. Ann. Med., 2001, 33, 272-285.
    • (2001) Ann. Med , vol.33 , pp. 272-285
    • Detera-Wadleigh, S.D.1
  • 10
    • 0036705074 scopus 로고    scopus 로고
    • Signalling networks in the pathophysiology and treatment of mood disorders
    • Gould, T. D.; Manji, H. K. Signalling networks in the pathophysiology and treatment of mood disorders. J. Psychosom. Res., 2002, 53, 687-697.
    • (2002) J. Psychosom. Res , vol.53 , pp. 687-697
    • Gould, T.D.1    Manji, H.K.2
  • 11
    • 34250313252 scopus 로고    scopus 로고
    • Targeting signal transduction pathways in the treatment of mood disorders: Recent insights into the relevance of the Wnt pathway
    • Gould, T. D.; Dow, E. R.; O'Donnell, K. C.; Chen, G.; Manji, H. K. Targeting signal transduction pathways in the treatment of mood disorders: recent insights into the relevance of the Wnt pathway. CNS Neurol. Disord. Drug Targets, 2007, 6, 193-204.
    • (2007) CNS Neurol. Disord. Drug Targets , vol.6 , pp. 193-204
    • Gould, T.D.1    Dow, E.R.2    O'Donnell, K.C.3    Chen, G.4    Manji, H.K.5
  • 12
    • 78650958063 scopus 로고    scopus 로고
    • The role of Wnt signalling and its interaction with diverse mechanisms of cellular apoptosis in the pathophysiology of bipolar disorder
    • Hu, L. W.; Kawamoto, E. M.; Brietzke, E.; Scavone, C.; Lafer, B. The role of Wnt signalling and its interaction with diverse mechanisms of cellular apoptosis in the pathophysiology of bipolar disorder. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2011, 35, 11-17.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , pp. 11-17
    • Hu, L.W.1    Kawamoto, E.M.2    Brietzke, E.3    Scavone, C.4    Lafer, B.5
  • 13
    • 45849117967 scopus 로고    scopus 로고
    • Wnt signal transduction pathways
    • Komiya, Y.; Habas, R. Wnt signal transduction pathways. Organogenesis, 2008, 4, 68-75.
    • (2008) Organogenesis , vol.4 , pp. 68-75
    • Komiya, Y.1    Habas, R.2
  • 15
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signalling pathway in development and disease
    • Logan, C. W.; Nusse, R. The Wnt signalling pathway in development and disease. Cell. Dev. Biol., 2004, 20, 781-810.
    • (2004) Cell. Dev. Biol , vol.20 , pp. 781-810
    • Logan, C.W.1    Nusse, R.2
  • 16
    • 79958199264 scopus 로고    scopus 로고
    • Synaptic Wnt signalling. A contributor to major psychiatric disorders
    • Okerlund, N. D.; Cheyette, B. N. R. Synaptic Wnt signalling. A contributor to major psychiatric disorders? J. Neurodev. Disord., 2011, 3, 162-174.
    • (2011) J. Neurodev. Disord , vol.3 , pp. 162-174
    • Okerlund, N.D.1    Cheyette, B.N.R.2
  • 17
    • 77951888466 scopus 로고    scopus 로고
    • Dishevelled: The hub of Wnt signalling
    • Gao, C.; Chen, Y. G. Dishevelled: The hub of Wnt signalling. Cell. Signal., 2010, 22, 717-727.
    • (2010) Cell. Signal , vol.22 , pp. 717-727
    • Gao, C.1    Chen, Y.G.2
  • 18
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multitasking kinase
    • Doble, B. W.; Woodgett, J. R. GSK-3: tricks of the trade for a multitasking kinase. J. Cell. Sci., 2003, 116, 1175-1186.
    • (2003) J. Cell. Sci , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 19
    • 0036810240 scopus 로고    scopus 로고
    • Lithium and valproic acid: Parallels and contrasts in diverse signalling contexts
    • Gurvich, N.; Klein, P. S. Lithium and valproic acid: parallels and contrasts in diverse signalling contexts. Pharmacol. Ther., 2002, 96, 45-66.
    • (2002) Pharmacol. Ther , vol.96 , pp. 45-66
    • Gurvich, N.1    Klein, P.S.2
  • 20
    • 18444399216 scopus 로고    scopus 로고
    • Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
    • McManus, E. J.; Sakamoto, K.; Armit, L. J.; Ronaldson, L.; Shpiro, N.; Marquez, R.; Alessi, D. R. Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis. EMBO J., 2005, 24, 1571-1583.
    • (2005) EMBO J , vol.24 , pp. 1571-1583
    • McManus, E.J.1    Sakamoto, K.2    Armit, L.J.3    Ronaldson, L.4    Shpiro, N.5    Marquez, R.6    Alessi, D.R.7
  • 22
    • 78650482080 scopus 로고    scopus 로고
    • Noncanonical Wnt signalling in vertebrate development, stem cells, and diseases
    • Sugimura, R.; Li, L. Noncanonical Wnt signalling in vertebrate development, stem cells, and diseases. Birth Defects Res. C Embryo Today, 2010, 90, 243-256.
    • (2010) Birth Defects Res. C Embryo Today , vol.90 , pp. 243-256
    • Sugimura, R.1    Li, L.2
  • 25
    • 77951600232 scopus 로고    scopus 로고
    • TAB2 scaffolds TAK1 and NLK in repressing canonical Wnt signalling
    • Li, M.; Wang, H.; Huang, T.; Wang, J.; Ding, Y.; Li, Z.; Zhang, J.; Li, L. TAB2 scaffolds TAK1 and NLK in repressing canonical Wnt signalling. J. Biol. Chem., 2010, 285, 13397-13404.
    • (2010) J. Biol. Chem , vol.285 , pp. 13397-13404
    • Li, M.1    Wang, H.2    Huang, T.3    Wang, J.4    Ding, Y.5    Li, Z.6    Zhang, J.7    Li, L.8
  • 26
    • 24644499046 scopus 로고    scopus 로고
    • Wnt and calcium signalling: β-Catenin-independent pathways
    • Kohn, A. D.; Moon, R. T. Wnt and calcium signalling: β-Catenin-independent pathways. Cell Calcium, 2005, 38, 439-446.
    • (2005) Cell Calcium , vol.38 , pp. 439-446
    • Kohn, A.D.1    Moon, R.T.2
  • 27
    • 32144436083 scopus 로고    scopus 로고
    • Activation of Rho and Rac by Wnt/frizzled signalling
    • Habas, R.; He, X. Activation of Rho and Rac by Wnt/frizzled signalling. Methods Enzymol., 2006, 406, 500-511.
    • (2006) Methods Enzymol , vol.406 , pp. 500-511
    • Habas, R.1    He, X.2
  • 28
    • 0036843202 scopus 로고    scopus 로고
    • Planar cell polarisation: Do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?
    • Mlodzik, M. Planar cell polarisation: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation? Trends Genet., 2002, 18, 564-571.
    • (2002) Trends Genet , vol.18 , pp. 564-571
    • Mlodzik, M.1
  • 29
    • 58149185543 scopus 로고    scopus 로고
    • Planar cell polarity signalling: From fly development to human disease
    • Simons, M.; Mlodzik, M. Planar cell polarity signalling: from fly development to human disease. Annu. Rev. Genet., 2008, 42, 517-540.
    • (2008) Annu. Rev. Genet , vol.42 , pp. 517-540
    • Simons, M.1    Mlodzik, M.2
  • 30
    • 81255193841 scopus 로고    scopus 로고
    • Neural stem cell regulation, fibroblast growth factors, and the developmental origins of neuropsychiatric disorders
    • Stevens, H. E.; Smith, K. M.; Rash, B. G.; Vaccarino, F. M. Neural stem cell regulation, fibroblast growth factors, and the developmental origins of neuropsychiatric disorders. Front. Neurosci., 2010, 4, 59.
    • (2010) Front. Neurosci , vol.4 , pp. 59
    • Stevens, H.E.1    Smith, K.M.2    Rash, B.G.3    Vaccarino, F.M.4
  • 31
    • 0025074908 scopus 로고
    • Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development
    • Thomas, K. R.; Capecchi, M. R. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature, 1990, 346, 847-850.
    • (1990) Nature , vol.346 , pp. 847-850
    • Thomas, K.R.1    Capecchi, M.R.2
  • 32
    • 35348900147 scopus 로고    scopus 로고
    • A dynamic gradient of Wnt signalling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus
    • Machon, O.; Backman, M.; Machonova, O.; Kozmik, Z.; Vacik, T.; Andersen, L.; Krauss, S. A dynamic gradient of Wnt signalling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus. Dev. Biol., 2007, 311, 223-237.
    • (2007) Dev. Biol , vol.311 , pp. 223-237
    • Machon, O.1    Backman, M.2    Machonova, O.3    Kozmik, Z.4    Vacik, T.5    Andersen, L.6    Krauss, S.7
  • 33
    • 0034084768 scopus 로고    scopus 로고
    • Roles of Wnt proteins in neural development and maintenance
    • Patapoutian, A.; Reichardt, L. F. Roles of Wnt proteins in neural development and maintenance. Curr. Opin. Neurobiol., 2000, 10, 392-399.
    • (2000) Curr. Opin. Neurobiol , vol.10 , pp. 392-399
    • Patapoutian, A.1    Reichardt, L.F.2
  • 34
    • 77954874401 scopus 로고    scopus 로고
    • GSK3 signalling in neural development
    • Hur, E. M.; Zhou, F. Q. GSK3 signalling in neural development. Nat. Rev. Neurosci., 2010, 11, 539-551.
    • (2010) Nat. Rev. Neurosci , vol.11 , pp. 539-551
    • Hur, E.M.1    Zhou, F.Q.2
  • 36
    • 23744471251 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • Harrison, P. J.; Weinberger, D. R. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol. Psychiatry, 2005, 10, 40-68. Errata corrige 10, 420; 10, 804.
    • Mol. Psychiatry , vol.10 , pp. 804
    • Harrison, P.J.1    Weinberger, D.R.2
  • 37
    • 65349191920 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia, revisited
    • Fatemi, S. H.; Folsom, T. D. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr. Bull., 2009, 35, 528-548.
    • (2009) Schizophr. Bull , vol.35 , pp. 528-548
    • Fatemi, S.H.1    Folsom, T.D.2
  • 40
    • 84872032948 scopus 로고    scopus 로고
    • Neurodevelopmental abnormalities in ADHD
    • Epub ahead of print, doi:10. 1007/7854
    • Vaidya, C. J. Neurodevelopmental abnormalities in ADHD. Curr. Top. Behav. Neurosci., May 4. 2011, Epub ahead of print, doi:10. 1007/7854. 2011. 38.
    • (2011) Curr. Top. Behav. Neurosci , vol.2011 , pp. 38
    • Vaidya, C.J.1
  • 41
    • 67650175927 scopus 로고    scopus 로고
    • Heterogeneity and the design of genetic studies in autism
    • Sutcliffe, J. S. Heterogeneity and the design of genetic studies in autism. Autism Res., 2008, 1, 205-206.
    • (2008) Autism Res , vol.1 , pp. 205-206
    • Sutcliffe, J.S.1
  • 45
    • 0036154321 scopus 로고    scopus 로고
    • GSK-3 and the neurodevelopmental hypothesis of schizophrenia
    • Kozlovsky, N.; Belmaker, R. H.; Agam, G. GSK-3 and the neurodevelopmental hypothesis of schizophrenia. Eur. Neuropsychopharmacol., 2002, 12, 13-25.
    • (2002) Eur. Neuropsychopharmacol , vol.12 , pp. 13-25
    • Kozlovsky, N.1    Belmaker, R.H.2    Agam, G.3
  • 46
    • 3342955475 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium
    • O'Brien, W. T.; Harper, A. D.; Jové, F.; Woodgett, J. R.; Maretto, S.; Piccolo, S.; Klein, P. S. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J. Neurosci., 2004, 24, 6791-6798.
    • (2004) J. Neurosci , vol.24 , pp. 6791-6798
    • O'Brien, W.T.1    Harper, A.D.2    Jové, F.3    Woodgett, J.R.4    Maretto, S.5    Piccolo, S.6    Klein, P.S.7
  • 50
    • 42949169723 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: Negative results
    • Bersudsky, Y.; Shaldubina, A.; Kozlovsky, N.; Woodgett, J. R.; Agam, G.; Belmaker, R. H. Glycogen synthase kinase-3β heterozygote knockout mice as a model of findings in postmortem schizophrenia brain or as a model of behaviors mimicking lithium action: negative results. Behav. Pharmacol., 2008, 19, 217-224.
    • (2008) Behav. Pharmacol , vol.19 , pp. 217-224
    • Bersudsky, Y.1    Shaldubina, A.2    Kozlovsky, N.3    Woodgett, J.R.4    Agam, G.5    Belmaker, R.H.6
  • 52
    • 77952970457 scopus 로고    scopus 로고
    • Hyperactivity and enhanced curiosity of mice expressing PKB/SGK-resistant glycogen synthase kinase-3 (GSK-3)
    • Ackermann TF.; Kempe DS.; Lang F.; Lang UE. Hyperactivity and enhanced curiosity of mice expressing PKB/SGK-resistant glycogen synthase kinase-3 (GSK-3). Cell. Physiol. Biochem., 2010, 25, 775-786.
    • (2010) Cell. Physiol. Biochem , vol.25 , pp. 775-786
    • Ackermann, T.F.1    Kempe, D.S.2    Lang, F.3    Lang, U.E.4
  • 56
    • 33750054677 scopus 로고    scopus 로고
    • Differential roles of glycogen synthase kinase-3 isoforms in the regulation of transcriptional activation
    • Liang, M. H.; Chuang, D. M. Differential roles of glycogen synthase kinase-3 isoforms in the regulation of transcriptional activation. J. Biol. Chem., 2006, 281, 30479-30484.
    • (2006) J. Biol. Chem , vol.281 , pp. 30479-30484
    • Liang, M.H.1    Chuang, D.M.2
  • 57
    • 33947519417 scopus 로고    scopus 로고
    • Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival
    • Liang, M. H.; Chuang, D. M. Regulation and function of glycogen synthase kinase-3 isoforms in neuronal survival. J. Biol. Chem., 2007, 282, 3904-3917.
    • (2007) J. Biol. Chem , vol.282 , pp. 3904-3917
    • Liang, M.H.1    Chuang, D.M.2
  • 58
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyper-phosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
    • Lucas, J. J.; Hernández, F.; Gómez-Ramos, P.; Morán, M. A.; Hen, R.; Avila, J. Decreased nuclear beta-catenin, tau hyper-phosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J., 2001, 20, 27-39.
    • (2001) EMBO J , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernández, F.2    Gómez-Ramos, P.3    Morán, M.A.4    Hen, R.5    Avila, J.6
  • 59
    • 10644255687 scopus 로고    scopus 로고
    • AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
    • Gould, T. D.; Einat, H.; Bhat, R.; Manji, H. K. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int. J. Neuropsychopharmacol., 2004, 7, 387-390.
    • (2004) Int. J. Neuropsychopharmacol , vol.7 , pp. 387-390
    • Gould, T.D.1    Einat, H.2    Bhat, R.3    Manji, H.K.4
  • 60
    • 1842420631 scopus 로고    scopus 로고
    • Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus
    • Kaidanovich-Beilin, O.; Milman, A.; Weizman, A.; Pick, C. G.; Eldar-Finkelman, H. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus. Biol. Psychiatry, 2004, 55, 781-784.
    • (2004) Biol. Psychiatry , vol.55 , pp. 781-784
    • Kaidanovich-Beilin, O.1    Milman, A.2    Weizman, A.3    Pick, C.G.4    Eldar-Finkelman, H.5
  • 62
    • 33847673530 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: A molecular link in the therapeutic action of lithium
    • Kaladchibachi, S. A.; Doble, B.; Anthopoulos, N.; Woodgett, J. R.; Manoukian, A. S. Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium. J. Circadian Rhythms, 2007, 5, 3.
    • (2007) J. Circadian Rhythms , vol.5 , pp. 3
    • Kaladchibachi, S.A.1    Doble, B.2    Anthopoulos, N.3    Woodgett, J.R.4    Manoukian, A.S.5
  • 63
    • 36549029252 scopus 로고    scopus 로고
    • Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder
    • Schloesser, R. J.; Huang, J.; Klein, P. S.; Manji, H. K. Cellular plasticity cascades in the pathophysiology and treatment of bipolar disorder. Neuropsychopharmacology, 2008, 33, 110-133.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 110-133
    • Schloesser, R.J.1    Huang, J.2    Klein, P.S.3    Manji, H.K.4
  • 64
    • 84867498271 scopus 로고    scopus 로고
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-Text Revision (DSM-IV-TR), Washington, D. C
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-Text Revision (DSM-IV-TR); American Psychiatric Publishing: Washington, D. C., 2000, pp. 345-428.
    • (2000) American Psychiatric Publishing , pp. 345-428
  • 65
    • 4243196940 scopus 로고    scopus 로고
    • Emerging experimental therapeutics for bipolar disorder: Insights from the molecular and cellular actions of current mood stabilisers
    • Gould, T. D.; Quiroz, J. A.; Singh, J.; Zarate, C. A.; Manji, H. K. Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilisers. Mol. Psychiatry, 2004, 9, 734-755.
    • (2004) Mol. Psychiatry , vol.9 , pp. 734-755
    • Gould, T.D.1    Quiroz, J.A.2    Singh, J.3    Zarate, C.A.4    Manji, H.K.5
  • 66
    • 0033014180 scopus 로고    scopus 로고
    • The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3
    • Chen, G.; Huang, L. D.; Jiang, Y. M.; Manji, H. K. The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3. J. Neurochem., 1999, 72, 1327-1330.
    • (1999) J. Neurochem , vol.72 , pp. 1327-1330
    • Chen, G.1    Huang, L.D.2    Jiang, Y.M.3    Manji, H.K.4
  • 67
    • 0036909443 scopus 로고    scopus 로고
    • Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium
    • De Sarno, P.; Li, X.; Jope, R. S. Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium. Neuropharmacology, 2002, 43, 1158-1164.
    • (2002) Neuropharmacology , vol.43 , pp. 1158-1164
    • de Sarno, P.1    Li, X.2    Jope, R.S.3
  • 68
    • 33646868139 scopus 로고    scopus 로고
    • Psychotropic drugs affect Ser9-phosphorylated GSK-3 beta protein levels in rodent frontal cortex
    • Kozlovsky, N.; Amar, S.; Belmaker, R. H.; Agam, G. Psychotropic drugs affect Ser9-phosphorylated GSK-3 beta protein levels in rodent frontal cortex. Int. J. Neuropsychopharmacol., 2006, 9, 337-342.
    • (2006) Int. J. Neuropsychopharmacol , vol.9 , pp. 337-342
    • Kozlovsky, N.1    Amar, S.2    Belmaker, R.H.3    Agam, G.4
  • 70
    • 34548012115 scopus 로고    scopus 로고
    • GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder
    • Rowe, M. K.; Wiest C.; Chuang, D. M. GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder. Neurosci. Biobehav. Rev., 2007, 31, 920-931.
    • (2007) Neurosci. Biobehav. Rev , vol.31 , pp. 920-931
    • Rowe, M.K.1    Wiest, C.2    Chuang, D.M.3
  • 71
    • 0346688565 scopus 로고    scopus 로고
    • In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3
    • Gould, T. D.; Chen, G.; Manji, H. K. In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology, 2004, 29, 32-38.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 32-38
    • Gould, T.D.1    Chen, G.2    Manji, H.K.3
  • 73
    • 0032573166 scopus 로고    scopus 로고
    • Glial reduction in the subgenual prefrontal cortex in mood disorders
    • Ongür, D.; Drevets, W. C.; Price, J. L. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc. Natl. Acad. Sci. U. S. A., 1998, 95, 13290-13295.
    • (1998) Proc. Natl. Acad. Sci. U. S. A , vol.95 , pp. 13290-13295
    • Ongür, D.1    Drevets, W.C.2    Price, J.L.3
  • 75
    • 0033625098 scopus 로고    scopus 로고
    • Low GSK-3beta immunoreactivity in postmortem frontal cortex of schizophrenic patients
    • Kozlovsky, N.; Belmaker, R. H.; Agam, G. Low GSK-3beta immunoreactivity in postmortem frontal cortex of schizophrenic patients. Am. J. Psychiatry, 2000, 157, 831-833.
    • (2000) Am. J. Psychiatry , vol.157 , pp. 831-833
    • Kozlovsky, N.1    Belmaker, R.H.2    Agam, G.3
  • 76
    • 0033459559 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β, β-catenin, and τ in postmortem bipolar brain
    • Lesort, M.; Greendorfer, A.; Stockmeier, C.; Johnson, G. V.; Jope, R. S. Glycogen synthase kinase-3β, β-catenin, and τ in postmortem bipolar brain. J. Neural Transm., 1999, 106, 1217-1222.
    • (1999) J. Neural Transm , vol.106 , pp. 1217-1222
    • Lesort, M.1    Greendorfer, A.2    Stockmeier, C.3    Johnson, G.V.4    Jope, R.S.5
  • 77
    • 13244253861 scopus 로고    scopus 로고
    • Anesthesia and post-mortem interval profoundly influence the regulatory serinephosphorylation of glycogen synthase kinase-3 in mouse brain
    • Li, X.; Friedman, A. B.; Roh, M. S.; Jope, R. S. Anesthesia and post-mortem interval profoundly influence the regulatory serinephosphorylation of glycogen synthase kinase-3 in mouse brain. J. Neurochem., 2005, 92, 701-704.
    • (2005) J. Neurochem , vol.92 , pp. 701-704
    • Li, X.1    Friedman, A.B.2    Roh, M.S.3    Jope, R.S.4
  • 78
    • 33846095134 scopus 로고    scopus 로고
    • Lithium regulates glycogen synthase kinase-3beta in human peripheral blood mononuclear cells: Implication in the treatment of bipolar disorder
    • Li, X.; Friedman, A. B.; Zhu, W.; Wang, L.; Boswell, S.; May, R. S.; Davis, L. L.; Jope, R. S. Lithium regulates glycogen synthase kinase-3beta in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorder. Biol. Psychiatry, 2007, 61, 216-222; Erratum, 61, 261.
    • (2007) Biol. Psychiatry , vol.61 , pp. 216-222
    • Li, X.1    Friedman, A.B.2    Zhu, W.3    Wang, L.4    Boswell, S.5    May, R.S.6    Davis, L.L.7    Jope, R.S.8
  • 79
    • 78049495832 scopus 로고    scopus 로고
    • Regulation of glycogen synthase kinase-3 during bipolar mania treatment
    • Li, X.; Liu, M.; Cai, Z.; Wang, G.; Li X. Regulation of glycogen synthase kinase-3 during bipolar mania treatment. Bipolar Disord., 2010, 12, 741-752.
    • (2010) Bipolar Disord , vol.12 , pp. 741-752
    • Li, X.1    Liu, M.2    Cai, Z.3    Wang, G.4    Li, X.5
  • 81
    • 34548297658 scopus 로고    scopus 로고
    • Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway
    • Matigian, N.; Windus, L.; Smith, H.; Filippich, C.; Pantelis, C.; McGrath, J.; Mowry, B.; Hayward, N. Expression profiling in monozygotic twins discordant for bipolar disorder reveals dysregulation of the WNT signalling pathway. Mol. Psychiatry, 2007, 12, 815-825.
    • (2007) Mol. Psychiatry , vol.12 , pp. 815-825
    • Matigian, N.1    Windus, L.2    Smith, H.3    Filippich, C.4    Pantelis, C.5    McGrath, J.6    Mowry, B.7    Hayward, N.8
  • 82
    • 4444350746 scopus 로고    scopus 로고
    • A glycogen synthase kinase 3-beta promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression
    • Benedetti, F.; Serretti, A.; Colombo, C.; Lorenzi, C.; Tubazio, V.; Smeraldi, E. A glycogen synthase kinase 3-beta promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression. Neurosci. Lett., 2004, 368, 123-126.
    • (2004) Neurosci. Lett , vol.368 , pp. 123-126
    • Benedetti, F.1    Serretti, A.2    Colombo, C.3    Lorenzi, C.4    Tubazio, V.5    Smeraldi, E.6
  • 83
    • 0346023025 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in glycogen synthase kinase 3-β promoter gene influences onset of illness in patients affected by bipolar disorder
    • Benedetti, F.; Bernasconi, A.; Lorenzi, C.; Pontiggia, A.; Serretti, A.; Colombo, C.; Smeraldi, E. A single nucleotide polymorphism in glycogen synthase kinase 3-β promoter gene influences onset of illness in patients affected by bipolar disorder. Neurosci. Lett., 2004, 355, 37-40.
    • (2004) Neurosci. Lett , vol.355 , pp. 37-40
    • Benedetti, F.1    Bernasconi, A.2    Lorenzi, C.3    Pontiggia, A.4    Serretti, A.5    Colombo, C.6    Smeraldi, E.7
  • 84
    • 13444269371 scopus 로고    scopus 로고
    • Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-β-50 T/C SNP
    • Benedetti, F.; Serretti, A.; Pontiggia, A.; Bernasconi, A.; Lorenzi, C.; Colombo, C.; Smeraldi, E. Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-β-50 T/C SNP. Neurosci. Lett., 2005, 376, 51-55.
    • (2005) Neurosci. Lett , vol.376 , pp. 51-55
    • Benedetti, F.1    Serretti, A.2    Pontiggia, A.3    Bernasconi, A.4    Lorenzi, C.5    Colombo, C.6    Smeraldi, E.7
  • 85
    • 79957869681 scopus 로고    scopus 로고
    • The impact of glycogen synthase kinase 3β gene on psychotic mania in bipolar disorder patients
    • Youn-Jung L.; Yong-Ku K. The impact of glycogen synthase kinase 3β gene on psychotic mania in bipolar disorder patients. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2011, 35, 1303-1308.
    • (2011) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.35 , pp. 1303-1308
    • Youn-Jung, L.1    Yong-Ku, K.2
  • 86
    • 46849110574 scopus 로고    scopus 로고
    • National Institute of Mental Health Genetics Initiative Bipolar Disorder Consortium. Association study of Wnt signalling pathway genes in bipolar disorder
    • Bipolar Disorder Phenome Group
    • Zandi, P. P.; Belmonte, P. L.; Willour, V. L.; Goes, F. S.; Badner, J. A.; Simpson, S. G.; Gershon, E. S.; McMahon, F. J.; DePaulo J. R. Jr.; Potash, J. B.; Bipolar Disorder Phenome Group; National Institute of Mental Health Genetics Initiative Bipolar Disorder Consortium. Association study of Wnt signalling pathway genes in bipolar disorder. Arch. Gen. Psychiatry, 2008, 65, 785-793.
    • (2008) Arch. Gen. Psychiatry , vol.65 , pp. 785-793
    • Zandi, P.P.1    Belmonte, P.L.2    Willour, V.L.3    Goes, F.S.4    Badner, J.A.5    Simpson, S.G.6    Gershon, E.S.7    McMahon, F.J.8    Depaulo, J.R.9    Potash, J.B.10
  • 88
    • 77952545472 scopus 로고    scopus 로고
    • The involvement of GSK3β in bipolar disorder: Integrating evidence from multiple types of genetic studies
    • Luykx, J. J.; Boks, M. P.; Terwindt, A. P.; Bakker, S.; Kahn, R. S. The involvement of GSK3β in bipolar disorder: integrating evidence from multiple types of genetic studies. Eur. Neuropsychopharmacol., 2010, 20, 357-368.
    • (2010) Eur. Neuropsychopharmacol , vol.20 , pp. 357-368
    • Luykx, J.J.1    Boks, M.P.2    Terwindt, A.P.3    Bakker, S.4    Kahn, R.S.5
  • 89
    • 77649339409 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β in the platelets of patients with mood disorders: Effect of treatment
    • Pandey, G. N.; Ren, X.; Rizavi, H. S.; Dwivedi, Y. Glycogen synthase kinase-3β in the platelets of patients with mood disorders: effect of treatment. J. Psychiatr. Res., 2010, 44, 143-148.
    • (2010) J. Psychiatr. Res , vol.44 , pp. 143-148
    • Pandey, G.N.1    Ren, X.2    Rizavi, H.S.3    Dwivedi, Y.4
  • 92
    • 82755189437 scopus 로고    scopus 로고
    • Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression
    • Voleti, B.; Tanis, K. Q.; Newton, S. S.; Duman, R. S. Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression. Biol. Psychiatry, 2012; 71, 51-58.
    • (2012) Biol. Psychiatry , vol.71 , pp. 51-58
    • Voleti, B.1    Tanis, K.Q.2    Newton, S.S.3    Duman, R.S.4
  • 94
    • 77953310084 scopus 로고    scopus 로고
    • Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis
    • Sahores, M.; Gibb, A.; Salinas, P. C. Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis. Development, 2010, 137, 2215-2225.
    • (2010) Development , vol.137 , pp. 2215-2225
    • Sahores, M.1    Gibb, A.2    Salinas, P.C.3
  • 95
    • 34748812548 scopus 로고    scopus 로고
    • The Frizzled family of unconventional Gprotein-coupled receptors
    • Schulte, G.; Bryja, V. The Frizzled family of unconventional Gprotein-coupled receptors. Trends Pharmacol. Sci., 2007, 28, 518-525.
    • (2007) Trends Pharmacol. Sci , vol.28 , pp. 518-525
    • Schulte, G.1    Bryja, V.2
  • 96
    • 34548046778 scopus 로고    scopus 로고
    • Chronic unpredictable stress decreases cell proliferation in the cerebral cortex of the adult rat
    • Banasr, M.; Valentine, G. W.; Li, X. Y.; Gourley, S. L.; Taylor, J. R.; Duman, R. S. Chronic unpredictable stress decreases cell proliferation in the cerebral cortex of the adult rat. Biol. Psychiatry, 2007, 62, 496-504.
    • (2007) Biol. Psychiatry , vol.62 , pp. 496-504
    • Banasr, M.1    Valentine, G.W.2    Li, X.Y.3    Gourley, S.L.4    Taylor, J.R.5    Duman, R.S.6
  • 97
    • 54149093900 scopus 로고    scopus 로고
    • Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviors
    • Banasr, M.; Duman, R. S. Glial loss in the prefrontal cortex is sufficient to induce depressive-like behaviors. Biol. Psychiatry, 2008, 64, 863-870.
    • (2008) Biol. Psychiatry , vol.64 , pp. 863-870
    • Banasr, M.1    Duman, R.S.2
  • 98
    • 0242384747 scopus 로고    scopus 로고
    • β-catenin is critical for dendritic morphogenesis
    • Yu, X.; Malenka, R. C. β-catenin is critical for dendritic morphogenesis. Nat. Neurosci., 2003, 6, 1169-1177.
    • (2003) Nat. Neurosci , vol.6 , pp. 1169-1177
    • Yu, X.1    Malenka, R.C.2
  • 99
    • 3242761438 scopus 로고    scopus 로고
    • In vivo regulation of glycogen synthase kinase-3β (GSK3β) by serotonergic activity in mouse brain
    • Li, X.; Zhu, W.; Roh, MS.; Friedman, A. B.; Rosborough, K.; Jope, R. S. In vivo regulation of glycogen synthase kinase-3β (GSK3β) by serotonergic activity in mouse brain. Neuropsychopharmacology, 2004, 29, 1426-1431.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1426-1431
    • Li, X.1    Zhu, W.2    Roh, M.S.3    Friedman, A.B.4    Rosborough, K.5    Jope, R.S.6
  • 100
    • 77956227380 scopus 로고    scopus 로고
    • Pathway-based approaches to imaging genetics association studies: Wnt signalling, GSK3beta substrates and major depression
    • Inkster, B.; Nichols, T. E.; Saemann, P. G.; Auer, D. P.; Holsboer, F.; Muglia, P.; Matthews, P. M. Pathway-based approaches to imaging genetics association studies: Wnt signalling, GSK3beta substrates and major depression. NeuroImage, 2010, 53, 908-917.
    • (2010) NeuroImage , vol.53 , pp. 908-917
    • Inkster, B.1    Nichols, T.E.2    Saemann, P.G.3    Auer, D.P.4    Holsboer, F.5    Muglia, P.6    Matthews, P.M.7
  • 102
    • 55449087175 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β gene is associated with antidepressant treatment response in Chinese major depressive disorder
    • Tsai, S. J.; Liou, Y. J.; Hong, C. J.; Yu, Y. W.; Chen, T. J. Glycogen synthase kinase-3β gene is associated with antidepressant treatment response in Chinese major depressive disorder. Pharmacogenom., J., 2008, 8, 384-390.
    • (2008) Pharmacogenom. J , vol.8 , pp. 384-390
    • Tsai, S.J.1    Liou, Y.J.2    Hong, C.J.3    Yu, Y.W.4    Chen, T.J.5
  • 103
    • 33846095133 scopus 로고    scopus 로고
    • Alteration in kinase activity but not in protein levels of protein kinase B and glycogen synthase kinase-3beta in ventral prefrontal cortex of depressed suicide victims
    • Karege, F.; Perroud, N.; Burkhardt, S.; Schwald, M.; Ballmann, E.; La Harpe, R.; Malafosse, A. Alteration in kinase activity but not in protein levels of protein kinase B and glycogen synthase kinase-3beta in ventral prefrontal cortex of depressed suicide victims. Biol. Psychiatry, 2007, 61, 240-245.
    • (2007) Biol. Psychiatry , vol.61 , pp. 240-245
    • Karege, F.1    Perroud, N.2    Burkhardt, S.3    Schwald, M.4    Ballmann, E.5    la Harpe, R.6    Malafosse, A.7
  • 104
    • 77957724723 scopus 로고    scopus 로고
    • Increased glycogen synthase kinase-3β mRNA level in the hippocampus of patients with major depression: A study using the stanley neuropathology consortium integrative database
    • Oh, D. H.; Park, Y. C.; Kim, S. H. Increased glycogen synthase kinase-3β mRNA level in the hippocampus of patients with major depression: a study using the stanley neuropathology consortium integrative database. Psychiatry Investig., 2010, 7, 202-207.
    • (2010) Psychiatry Investig , vol.7 , pp. 202-207
    • Oh, D.H.1    Park, Y.C.2    Kim, S.H.3
  • 105
    • 77649272940 scopus 로고    scopus 로고
    • Association between glycogen synthase kinase-3β gene polymorphisms and major depression and suicidal behavior in a Korean population
    • Yooh, H. K.; Kim, Y. K. Association between glycogen synthase kinase-3β gene polymorphisms and major depression and suicidal behavior in a Korean population. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2010, 34, 331-334.
    • (2010) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.34 , pp. 331-334
    • Yooh, H.K.1    Kim, Y.K.2
  • 106
    • 84859001540 scopus 로고    scopus 로고
    • The Bipolar Genome Study (BiGS) Consortiumgenome-wide association study of attempted suicide
    • doi:10. 1038/mp. 2011. 4
    • Willour, V. L.; Seifuddin, F.; Mahon, P. B.; Jancic, D.; Pirooznia, M.; Steele, J.; Schweizer, B.; Goes, F. S.; Mondimore, F. M.; Mackinnon, D. F; The Bipolar Genome Study (BiGS) Consortium.; Perlis, R. H.; Lee, P. H.; Huang, J.; Kelsoe, J. R.; Shilling, P. D.; Rietschel, M.; Nöthen, M.; Cichon, S.; Gurling, H.; Purcell, S.; Smoller, J. W.; Craddock, N.; Depaulo, J. R. Jr.; Schulze, T. G.; McMahon, F. J.; Zandi, P. P.; Potash, J. B. A genome-wide association study of attempted suicide. Mol. Psychiatry, 2011, doi:10. 1038/mp. 2011. 4.
    • (2011) Mol. Psychiatry
    • Willour, V.L.1    Seifuddin, F.2    Mahon, P.B.3    Jancic, D.4    Pirooznia, M.5    Steele, J.6    Schweizer, B.7    Goes, F.S.8    Mondimore, F.M.9    Mackinnon, D.F.10
  • 107
    • 0033035485 scopus 로고    scopus 로고
    • Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: Therapeutic implications
    • Manji, H. K.; Bebchuk, J. M.; Moore, G. J.; Glitz, D.; Hasanat, K. A.; Chen, G. Modulation of CNS signal transduction pathways and gene expression by mood-stabilizing agents: therapeutic implications. J. Clin. Psychiatry, 1999, 60 (Suppl 2), 27-39.
    • (1999) J. Clin. Psychiatry , vol.60 , Issue.2 SUPPL. , pp. 27-39
    • Manji, H.K.1    Bebchuk, J.M.2    Moore, G.J.3    Glitz, D.4    Hasanat, K.A.5    Chen, G.6
  • 108
    • 56649097561 scopus 로고    scopus 로고
    • Looking at lithium: Molecular moods and complex behaviour
    • Beaulieu, J. M.; Caron, M. G. Looking at lithium: molecular moods and complex behaviour. Mol. Interv., 2008; 8, 230-241.
    • (2008) Mol. Interv , vol.8 , pp. 230-241
    • Beaulieu, J.M.1    Caron, M.G.2
  • 110
    • 0032557889 scopus 로고    scopus 로고
    • Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats
    • Nonaka, S, Chuang, D. M. Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats. Neuroreport, 1998, 9, 2081-2084.
    • (1998) Neuroreport , vol.9 , pp. 2081-2084
    • Nonaka, S.1    Chuang, D.M.2
  • 111
    • 0032478088 scopus 로고    scopus 로고
    • Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx
    • Nonaka, S.; Hough, CJ.; Chuang, D. M. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc. Natl. Acad. Sci. U. S. A., 1998, 95, 2642-2647.
    • (1998) Proc. Natl. Acad. Sci. U. S. A , vol.95 , pp. 2642-2647
    • Nonaka, S.1    Hough, C.J.2    Chuang, D.M.3
  • 112
    • 0031870871 scopus 로고    scopus 로고
    • Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine
    • Nonaka, S.; Katsube, N.; Chuang, D. M. Lithium protects rat cerebellar granule cells against apoptosis induced by anticonvulsants, phenytoin and carbamazepine. J. Pharmacol. Exp. Ther., 1998, 286, 539-547.
    • (1998) J. Pharmacol. Exp. Ther , vol.286 , pp. 539-547
    • Nonaka, S.1    Katsube, N.2    Chuang, D.M.3
  • 116
    • 0035960005 scopus 로고    scopus 로고
    • Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease
    • Wei, H.; Qin, Z. H.; Senatorov, V. V.; Wei, W.; Wang, Y.; Qian, Y.; Chuang, D. M. Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington's disease. Neuroscience, 2001, 106, 603-612.
    • (2001) Neuroscience , vol.106 , pp. 603-612
    • Wei, H.1    Qin, Z.H.2    Senatorov, V.V.3    Wei, W.4    Wang, Y.5    Qian, Y.6    Chuang, D.M.7
  • 117
    • 0032827466 scopus 로고    scopus 로고
    • Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?
    • Manji, H. K.; Moore, G. J.; Chen, G. Lithium at 50: have the neuroprotective effects of this unique cation been overlooked? Biol. Psychiatry, 1999, 46, 929-940.
    • (1999) Biol. Psychiatry , vol.46 , pp. 929-940
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 118
    • 0033587742 scopus 로고    scopus 로고
    • Lithium Activates the Serine/threonine Kinase Akt-1 and Suppresses Glutamate-induced Inhibition of Akt-1 Activity In Neurons
    • Chalecka-Franaszek, E.; Chuang, D. M. Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons. Proc. Natl. Acad. Sci. U. S. A., 1999, 96, 8745-8750.
    • (1999) Proc. Natl. Acad. Sci. U. S. A , vol.96 , pp. 8745-8750
    • Chalecka-Franaszek, E.1    Chuang, D.M.2
  • 120
    • 0042357237 scopus 로고    scopus 로고
    • Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3
    • Zhang, F.; Phiel, C. J.; Spece, L.; Gurvich, N.; Klein, P. S. Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3. J. Biol. Chem., 2003, 278, 33067-33077.
    • (2003) J. Biol. Chem , vol.278 , pp. 33067-33077
    • Zhang, F.1    Phiel, C.J.2    Spece, L.3    Gurvich, N.4    Klein, P.S.5
  • 121
    • 0042379932 scopus 로고    scopus 로고
    • Lithium and GSK-3: One inhibitor, two inhibitory actions, multiple outcomes
    • Jope RS. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends Pharmacol. Sci., 2003, 24, 441-443.
    • (2003) Trends Pharmacol. Sci , vol.24 , pp. 441-443
    • Jope, R.S.1
  • 122
    • 35848951872 scopus 로고    scopus 로고
    • Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta-50T/C single nucleotide polymorphism
    • Adli, M.; Hollinde, D. L.; Stamm, T.; Wiethoff, K.; Tsahuridu, M.; Kirchheiner, J.; Heinz, A.; Bauer, M. Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta-50T/C single nucleotide polymorphism. Biol. Psychiatry, 2007, 62, 1295-1302.
    • (2007) Biol. Psychiatry , vol.62 , pp. 1295-1302
    • Adli, M.1    Hollinde, D.L.2    Stamm, T.3    Wiethoff, K.4    Tsahuridu, M.5    Kirchheiner, J.6    Heinz, A.7    Bauer, M.8
  • 132
    • 80052964809 scopus 로고    scopus 로고
    • Evidence for antimanic efficacy of glycogen synthase kinase-3 (GSK3) inhibitors in a strain-specific model of acute mania
    • Kalinichev, M.; Dawson, L. A. Evidence for antimanic efficacy of glycogen synthase kinase-3 (GSK3) inhibitors in a strain-specific model of acute mania. Int. J. Neuropsychopharmacol., 2011, 14, 1051-1067.
    • (2011) Int. J. Neuropsychopharmacol , vol.14 , pp. 1051-1067
    • Kalinichev, M.1    Dawson, L.A.2
  • 133
    • 0038433246 scopus 로고    scopus 로고
    • Effect of chronic stress on spatial memory in rats is attenuated by lithium treatment
    • Vasconcellos, A. P.; Tabajara, A. S.; Ferrari, C.; Rocha, E.; Dalmaz, C. Effect of chronic stress on spatial memory in rats is attenuated by lithium treatment. Physiol. Behav., 2003, 79, 143-149.
    • (2003) Physiol. Behav , vol.79 , pp. 143-149
    • Vasconcellos, A.P.1    Tabajara, A.S.2    Ferrari, C.3    Rocha, E.4    Dalmaz, C.5
  • 134
    • 1642280965 scopus 로고    scopus 로고
    • Stress-induced structural remodeling in hippocampus: Prevention by lithium treatment
    • Wood, G. E.; Young, L. T.; Reagan, L. P.; Chen, B.; McEwen, B. S. Stress-induced structural remodeling in hippocampus: prevention by lithium treatment. Proc. Natl. Acad. Sci. U. S. A., 2004, 101, 3973-3978.
    • (2004) Proc. Natl. Acad. Sci. U. S. A , vol.101 , pp. 3973-3978
    • Wood, G.E.1    Young, L.T.2    Reagan, L.P.3    Chen, B.4    McEwen, B.S.5
  • 135
    • 40949125640 scopus 로고    scopus 로고
    • Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: The role of glycogen-synthase-kinase-3β
    • Silva, R.; Mesquita, A. R.; Bessa, J.; Sousa, J. C.; Sotiropoulos, I.; Leão, P.; Almeida, O. F.; Sousa, N. Lithium blocks stress-induced changes in depressive-like behavior and hippocampal cell fate: the role of glycogen-synthase-kinase-3β. Neuroscience, 2008, 152, 656-669.
    • (2008) Neuroscience , vol.152 , pp. 656-669
    • Silva, R.1    Mesquita, A.R.2    Bessa, J.3    Sousa, J.C.4    Sotiropoulos, I.5    Leão, P.6    Almeida, O.F.7    Sousa, N.8
  • 137
    • 0038604800 scopus 로고    scopus 로고
    • Valproate
    • Bowden, C. L. Valproate. Bipolar Disord., 2003, 5, 189-202.
    • (2003) Bipolar Disord , vol.5 , pp. 189-202
    • Bowden, C.L.1
  • 138
    • 5144226319 scopus 로고    scopus 로고
    • Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds
    • Werstuck, G. H.; Kim, A. J.; Brenstrum, T.; Ohnmacht, S. A.; Panna, E.; Capretta, A. Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds. Bioorg. Med. Chem. Lett., 2004, 14, 5465-5467.
    • (2004) Bioorg. Med. Chem. Lett , vol.14 , pp. 5465-5467
    • Werstuck, G.H.1    Kim, A.J.2    Brenstrum, T.3    Ohnmacht, S.A.4    Panna, E.5    Capretta, A.6
  • 139
    • 14044261099 scopus 로고    scopus 로고
    • Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3
    • Kim, A. J.; Shi, Y.; Austin, R. C.; Werstuck, G. H. Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3. J. Cell Sci., 2005, 118, 89-99.
    • (2005) J. Cell Sci , vol.118 , pp. 89-99
    • Kim, A.J.1    Shi, Y.2    Austin, R.C.3    Werstuck, G.H.4
  • 140
    • 0035965343 scopus 로고    scopus 로고
    • Histone Deacetylase is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabiliser, and Teratogen
    • Phiel, C. J.; Zhang, F.; Huang, E. Y.; Guenther, M. G.; Lazar, M. A.; Klein, P. S. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabiliser, and teratogen. J. Biol. Chem., 2001, 276, 36734-36741.
    • (2001) J. Biol. Chem , vol.276 , pp. 36734-36741
    • Phiel, C.J.1    Zhang, F.2    Huang, E.Y.3    Guenther, M.G.4    Lazar, M.A.5    Klein, P.S.6
  • 142
    • 20944435414 scopus 로고    scopus 로고
    • Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: A screening approach for new bipolar disorder drugs derived from the valproic acid core structure
    • Eickholt, B. J.; Towers, G. J.; Ryves, W. J.; Eikel, D.; Adley, K.; Ylinen, L. M.; Chadborn, N. H.; Harwood, A. J.; Nau, H.; Williams, R. S. Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure. Mol. Pharmacol., 2005, 67, 1426-1433.
    • (2005) Mol. Pharmacol , vol.67 , pp. 1426-1433
    • Eickholt, B.J.1    Towers, G.J.2    Ryves, W.J.3    Eikel, D.4    Adley, K.5    Ylinen, L.M.6    Chadborn, N.H.7    Harwood, A.J.8    Nau, H.9    Williams, R.S.10
  • 143
    • 14744305104 scopus 로고    scopus 로고
    • Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death
    • Jin, N.; Kovacs, A. D.; Sui, Z.; Dewhurst, S.; Maggirwar, S. B. Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death. Neuropharmacology, 2005, 48, 576-583.
    • (2005) Neuropharmacology , vol.48 , pp. 576-583
    • Jin, N.1    Kovacs, A.D.2    Sui, Z.3    Dewhurst, S.4    Maggirwar, S.B.5
  • 144
    • 0034806590 scopus 로고    scopus 로고
    • CREB DNA Binding Activity is Inhibited By Glycogen Synthase Kinase-3 Beta and Facilitated By Lithium
    • Grimes, C. A.; Jope, R. S. CREB DNA binding activity is inhibited by glycogen synthase kinase-3 beta and facilitated by lithium. J. Neurochem., 2001, 78, 1219-1232.
    • (2001) J. Neurochem , vol.78 , pp. 1219-1232
    • Grimes, C.A.1    Jope, R.S.2
  • 145
    • 40449135649 scopus 로고    scopus 로고
    • Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: Roles of glycogen synthase kinase-3 inhibition
    • Leng, Y.; Liang, M. H.; Ren, M.; Marinova, Z.; Leeds, P.; Chuang, D. M. Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition. J. Neurosci., 2008, 28, 2576-2588.
    • (2008) J. Neurosci , vol.28 , pp. 2576-2588
    • Leng, Y.1    Liang, M.H.2    Ren, M.3    Marinova, Z.4    Leeds, P.5    Chuang, D.M.6
  • 146
    • 50849134835 scopus 로고    scopus 로고
    • Up-regulation of protein l-isoaspartyl methyltransferase expression by lithium is mediated by glycogen synthase kinase-3 inactivation and beta-catenin stabilisation
    • Lamarre, M.; Desrosiers, RR. Up-regulation of protein l-isoaspartyl methyltransferase expression by lithium is mediated by glycogen synthase kinase-3 inactivation and beta-catenin stabilisation. Neuropharmacology, 2008, 55, 669-676.
    • (2008) Neuropharmacology , vol.55 , pp. 669-676
    • Lamarre, M.1    Desrosiers, R.R.2
  • 147
    • 67651005342 scopus 로고    scopus 로고
    • Early effects of mood stabilisers on the Akt/ GSK-3beta signalling pathway and on cell survival and proliferation
    • Aubry, J. M.; Schwald, M.; Ballmann, E.; Karege, F. Early effects of mood stabilisers on the Akt/ GSK-3beta signalling pathway and on cell survival and proliferation. Psychopharmacology (Berl), 2009, 205, 419-429.
    • (2009) Psychopharmacology (Berl) , vol.205 , pp. 419-429
    • Aubry, J.M.1    Schwald, M.2    Ballmann, E.3    Karege, F.4
  • 148
    • 20344363201 scopus 로고    scopus 로고
    • GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid
    • Ryves, W. J.; Dalton, E. C.; Harwood, A. J.; Williams, R. S. GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid. Bipolar Disord., 2005, 7, 260-265.
    • (2005) Bipolar Disord , vol.7 , pp. 260-265
    • Ryves, W.J.1    Dalton, E.C.2    Harwood, A.J.3    Williams, R.S.4
  • 149
    • 0034971060 scopus 로고    scopus 로고
    • Activation of Glycogen Synthase Kinase 3 Beta (GSK-3β) By Platelet Activating Factor Mediates Migration and Cell Death In Cerebellar Granule Neurons
    • Tong, N.; Sanchez, J. F.; Maggirwar, S. B.; Ramirez, S. H.; Guo, H.; Dewhurst, S.; Gelbard, H. A. Activation of glycogen synthase kinase 3 beta (GSK-3β) by platelet activating factor mediates migration and cell death in cerebellar granule neurons. Eur. J. Neurosci., 2001, 13, 1913-1922.
    • (2001) Eur. J. Neurosci , vol.13 , pp. 1913-1922
    • Tong, N.1    Sanchez, J.F.2    Maggirwar, S.B.3    Ramirez, S.H.4    Guo, H.5    Dewhurst, S.6    Gelbard, H.A.7
  • 150
    • 0038164860 scopus 로고    scopus 로고
    • Lack of effect of mood stabilisers or neuroleptics on GSK-3 protein levels and GSK-3 activity
    • Kozlovsky, N.; Nadri, C.; Belmaker, R. H.; Agam, G. Lack of effect of mood stabilisers or neuroleptics on GSK-3 protein levels and GSK-3 activity. Int. J. Neuropsychopharmacol., 2003, 6, 117-120.
    • (2003) Int. J. Neuropsychopharmacol , vol.6 , pp. 117-120
    • Kozlovsky, N.1    Nadri, C.2    Belmaker, R.H.3    Agam, G.4
  • 151
    • 13244257028 scopus 로고    scopus 로고
    • Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: Protection by mood stabilisers and imipramine
    • Roh, M. S.; Eom, T. Y.; Zmijewska, A. A.; De Sarno, P.; Roth, K. A.; Jope, R. S. Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilisers and imipramine. Biol. Psychiatry, 2005, 57, 278-286.
    • (2005) Biol. Psychiatry , vol.57 , pp. 278-286
    • Roh, M.S.1    Eom, T.Y.2    Zmijewska, A.A.3    de Sarno, P.4    Roth, K.A.5    Jope, R.S.6
  • 154
    • 0036843408 scopus 로고    scopus 로고
    • An investigation of the Wnt-signalling pathway in the prefrontal cortex in schizophrenia, bipolar disorder and major depressive disorder
    • Beasley, C.; Cotter, D.; Everall, I. An investigation of the Wnt-signalling pathway in the prefrontal cortex in schizophrenia, bipolar disorder and major depressive disorder. Schizophr. Res., 2002, 58, 63-67.
    • (2002) Schizophr. Res , vol.58 , pp. 63-67
    • Beasley, C.1    Cotter, D.2    Everall, I.3
  • 155
    • 0036310511 scopus 로고    scopus 로고
    • BPNF-mediated signal transduction is modulated by GSK3β and mood stabilizing agents
    • Mai, L.; Jope, R. S.; Li, X. BPNF-mediated signal transduction is modulated by GSK3β and mood stabilizing agents. J. Neurochem., 2002, 82, 75-83.
    • (2002) J. Neurochem , vol.82 , pp. 75-83
    • Mai, L.1    Jope, R.S.2    Li, X.3
  • 156
    • 0023215296 scopus 로고
    • Implications of normal brain development for the pathogenesis of schizophrenia
    • Weinberger, D. R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry, 1987, 44, 660-669.
    • (1987) Arch. Gen. Psychiatry , vol.44 , pp. 660-669
    • Weinberger, D.R.1
  • 157
    • 0023918477 scopus 로고
    • Physiological Dysfunction of Dorsolateral Prefrontal Cortex In Schizophrenia. III. a New Cohort and Evidence For a Monoaminergic Mechanism
    • Weinberger, D. R.; Berman, K. F.; Illowsky, B. P. Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. III. A new cohort and evidence for a monoaminergic mechanism. Arch. Gen. Psychiatry, 1988, 45, 609-615.
    • (1988) Arch. Gen. Psychiatry , vol.45 , pp. 609-615
    • Weinberger, D.R.1    Berman, K.F.2    Illowsky, B.P.3
  • 159
    • 10044239533 scopus 로고    scopus 로고
    • Prefrontal atrophy in first episodes of schizophrenia associated with limbic metabolic hyperactivity
    • Molina, V.; Sanz, J.; Sarramea, F.; Benito, C.; Palomo, T. Prefrontal atrophy in first episodes of schizophrenia associated with limbic metabolic hyperactivity. J. Psychiatr. Res., 2005, 39, 117-127.
    • (2005) J. Psychiatr. Res , vol.39 , pp. 117-127
    • Molina, V.1    Sanz, J.2    Sarramea, F.3    Benito, C.4    Palomo, T.5
  • 160
    • 33947583891 scopus 로고    scopus 로고
    • The Akt-GSK-3 signalling cascade in the actions of dopamine
    • Beaulieu, J. M.; Gainetdinov, R. R.; Caron, MG. The Akt-GSK-3 signalling cascade in the actions of dopamine. Trends Pharmacol. Sci., 2007, 28, 166-172.
    • (2007) Trends Pharmacol. Sci , vol.28 , pp. 166-172
    • Beaulieu, J.M.1    Gainetdinov, R.R.2    Caron, M.G.3
  • 161
    • 1342308071 scopus 로고    scopus 로고
    • The effects of clozapine on the GSK-3-mediated signalling pathway
    • Kang, U. G.; Seo, M, S.; Roh, M. S.; Kim, Y.; Yoon, S. C.; Kim, Y. S. The effects of clozapine on the GSK-3-mediated signalling pathway. FEBS Lett., 2004, 560, 115-119.
    • (2004) FEBS Lett , vol.560 , pp. 115-119
    • Kang, U.G.1    Seo, M.2
  • 162
    • 34250179171 scopus 로고    scopus 로고
    • Activation of the Canonical Wnt Pathway By the Antipsychotics Haloperidol and Clozapine Involves Disheveled-3
    • Sutton, L. P.; Honardoust, D.; Mouyal, J.; Rajakumar, N.; Rushlow, W. J. Activation of the canonical Wnt pathway by the antipsychotics haloperidol and clozapine involves disheveled-3. J. Neurochem., 2007, 102, 153-169.
    • (2007) J. Neurochem , vol.102 , pp. 153-169
    • Sutton, L.P.1    Honardoust, D.2    Mouyal, J.3    Rajakumar, N.4    Rushlow, W.J.5
  • 163
    • 33846279370 scopus 로고    scopus 로고
    • Not only lithium: Regulation of glycogen synthase kinase-3 by antipsychotics and serotonergic drugs
    • Beaulieu, J. M. Not only lithium: regulation of glycogen synthase kinase-3 by antipsychotics and serotonergic drugs. Int. J. Neuropsychopharmacol., 2007, 10, 3-6.
    • (2007) Int. J. Neuropsychopharmacol , vol.10 , pp. 3-6
    • Beaulieu, J.M.1
  • 165
    • 83055176458 scopus 로고    scopus 로고
    • The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signalling
    • Sutton, L. P.; Rushlow, W. J. The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signalling. Neuroscience, 2011, 199, 116-24.
    • (2011) Neuroscience , vol.199 , pp. 116-124
    • Sutton, L.P.1    Rushlow, W.J.2
  • 166
    • 14644389398 scopus 로고    scopus 로고
    • Antipsychotics alter the protein expression levels of β-catenin and GSK-3 in the rat medial prefrontal cortex and striatum
    • Alimohamad, H.; Rajakumar, N.; Seah, Y. H.; Rushlow, W. Antipsychotics alter the protein expression levels of β-catenin and GSK-3 in the rat medial prefrontal cortex and striatum. Biol. Psychiatry, 2005, 57, 533-542.
    • (2005) Biol. Psychiatry , vol.57 , pp. 533-542
    • Alimohamad, H.1    Rajakumar, N.2    Seah, Y.H.3    Rushlow, W.4
  • 167
    • 26844572307 scopus 로고    scopus 로고
    • The effects of antipsychotics on β-catenin, glycogen synthase kinase-3 and disheveled in the ventral midbrain of rats
    • Alimohamad, H.; Sutton, L.; Mouyal, J.; Rajakumar, N.; Rushlow, W. J. The effects of antipsychotics on β-catenin, glycogen synthase kinase-3 and disheveled in the ventral midbrain of rats. J. Neurochem., 2005, 95, 513-525.
    • (2005) J. Neurochem , vol.95 , pp. 513-525
    • Alimohamad, H.1    Sutton, L.2    Mouyal, J.3    Rajakumar, N.4    Rushlow, W.J.5
  • 168
    • 34447115083 scopus 로고    scopus 로고
    • Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex
    • Roh, M. S.; Seo, M. S.; Kim, Y.; Kim, S. H.; Jeon, W. J.; Ahn, Y. M.; Kang, U. G.; Juhnn, Y. S.; Kim, Y. S. Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex. Exp., Mol., Med., 2007, 39, 353-360.
    • (2007) Exp., Mol., Med , vol.39 , pp. 353-360
    • Roh, M.S.1    Seo, M.S.2    Kim, Y.3    Kim, S.H.4    Jeon, W.J.5    Ahn, Y.M.6    Kang, U.G.7    Juhnn, Y.S.8    Kim, Y.S.9
  • 169
    • 0842310838 scopus 로고    scopus 로고
    • Convergent evidence for impaired AKT1-GSK3β signalling in schizophrenia
    • Emamian, E. S.; Hall, D.; Birnbaum, M. J.; Karayiorgou, M.; Gogos, J. A. Convergent evidence for impaired AKT1-GSK3β signalling in schizophrenia. Nat. Genet., 2004, 36, 131-137.
    • (2004) Nat. Genet , vol.36 , pp. 131-137
    • Emamian, E.S.1    Hall, D.2    Birnbaum, M.J.3    Karayiorgou, M.4    Gogos, J.A.5
  • 170
    • 2642545991 scopus 로고    scopus 로고
    • Neurotoxic potential of haloperidol in comparison with risperidone: Implication of Akt-mediated signal changes by haloperidol
    • Ukai, W.; Ozawa, H.; Tateno, M.; Hashimoto, E.; Saito, T. Neurotoxic potential of haloperidol in comparison with risperidone: implication of Akt-mediated signal changes by haloperidol. J. Neural. Transm., 2004, 111, 667-681.
    • (2004) J. Neural. Transm , vol.111 , pp. 667-681
    • Ukai, W.1    Ozawa, H.2    Tateno, M.3    Hashimoto, E.4    Saito, T.5
  • 171
    • 34848926265 scopus 로고    scopus 로고
    • Haloperidol induces the nuclear translocation of phosphatidylinositol 3'-kinase to disrupt Akt phosphorylation in PC12 cells
    • Dai, Y.; Wei, Z.; Sephton, C. F.; Zhang, D.; Anderson, D. H.; Mousseau, D. D. Haloperidol induces the nuclear translocation of phosphatidylinositol 3'-kinase to disrupt Akt phosphorylation in PC12 cells. J. Psychiatry Neurosci., 2007, 32, 323-330.
    • (2007) J. Psychiatry Neurosci , vol.32 , pp. 323-330
    • Dai, Y.1    Wei, Z.2    Sephton, C.F.3    Zhang, D.4    Anderson, D.H.5    Mousseau, D.D.6
  • 172
    • 72549097250 scopus 로고    scopus 로고
    • Spiperone enhances intracellular calcium level and inhibits the Wnt signalling pathway
    • Lu, D.; Carson, D. A. Spiperone enhances intracellular calcium level and inhibits the Wnt signalling pathway. BMC Pharmacol., 2009, 9, 13.
    • (2009) BMC Pharmacol , vol.9 , pp. 13
    • Lu, D.1    Carson, D.A.2
  • 173
    • 84255190041 scopus 로고    scopus 로고
    • A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health
    • doi: 10. 1503/jpn. 110011. [Epub ahead of print
    • Beaulieu, J. M. A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health. J. Psychiatry Neurosci., 2011, 36, 4, 110011. doi: 10. 1503/jpn. 110011. [Epub ahead of print].
    • (2011) J. Psychiatry Neurosci , vol.36 , pp. 110011
    • Beaulieu, J.M.1
  • 175
    • 78651312903 scopus 로고    scopus 로고
    • Is glycogen synthase kinase-3 a central modulator in mood regulation?
    • Li, X.; Jope, R. S. Is glycogen synthase kinase-3 a central modulator in mood regulation? Neuropsychopharmacology, 2010, 35, 2143-2154.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2143-2154
    • Li, X.1    Jope, R.S.2
  • 176
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg, J. E.; Eisch, A. J.; Nestler, E. J.; Duman, R. S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci., 2000, 20, 9104-9110.
    • (2000) J. Neurosci , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 177
    • 78149426142 scopus 로고    scopus 로고
    • The roles of BPNF, pCREB and Wnt3a in the latent period preceding activation of progenitor cell mitosis in the adult dentate gyrus by fluoxetine
    • Pinnock, S. B.; Blake, A. M.; Platt, N. J.; Herbert, J. The roles of BPNF, pCREB and Wnt3a in the latent period preceding activation of progenitor cell mitosis in the adult dentate gyrus by fluoxetine. PLoS One, 2010, 5, e13652.
    • (2010) PLoS One , vol.5
    • Pinnock, S.B.1    Blake, A.M.2    Platt, N.J.3    Herbert, J.4
  • 178
    • 84856332025 scopus 로고    scopus 로고
    • Subchronic treatment with fluoxetine and ketanserin increases hippocampal brain-derived neurotrophic factor, β-catenin and antidepressant-like effects
    • Pilar-Cuéllar, F.; Vidal, R.; Pazos, A. Subchronic treatment with fluoxetine and ketanserin increases hippocampal brain-derived neurotrophic factor, β-catenin and antidepressant-like effects. Br. J. Pharmacol., 2012, 165, 1046-1057.
    • (2012) Br. J. Pharmacol , vol.165 , pp. 1046-1057
    • Pilar-Cuéllar, F.1    Vidal, R.2    Pazos, A.3
  • 179
    • 45849085732 scopus 로고    scopus 로고
    • A role for nuclear β-catenin in SNRI antidepressant-induced hippocampal cell proliferation
    • Mostany, R.; Valdizán, E. M.; Pazos, A. A role for nuclear β-catenin in SNRI antidepressant-induced hippocampal cell proliferation. Neuropharmacology, 2008, 55, 18-26.
    • (2008) Neuropharmacology , vol.55 , pp. 18-26
    • Mostany, R.1    Valdizán, E.M.2    Pazos, A.3
  • 181
    • 78651066495 scopus 로고    scopus 로고
    • Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signalling in the thoracic aorta of ovariectomized rats with abdominal aortic banding
    • Bhuiyan, M. S.; Tagashira, H.; Fukunaga, K. Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signalling in the thoracic aorta of ovariectomized rats with abdominal aortic banding. Eur. J. Pharmacol., 2011, 650, 621-628.
    • (2011) Eur. J. Pharmacol , vol.650 , pp. 621-628
    • Bhuiyan, M.S.1    Tagashira, H.2    Fukunaga, K.3
  • 183
    • 21644475248 scopus 로고    scopus 로고
    • Inhibitory effect of imipramine on the human corticotropin-releasing-hormone gene promoter activity operates through a PI3-K/AKT mediated pathway
    • Basta-Kaim, A.; Budziszewska, B.; Jaworska-Feil, L.; Tetich, M.; Kubera, M.; Leśkiewicz, M.; Lasoń, W. Inhibitory effect of imipramine on the human corticotropin-releasing-hormone gene promoter activity operates through a PI3-K/AKT mediated pathway. Neuropharmacology, 2005, 49, 156-164.
    • (2005) Neuropharmacology , vol.49 , pp. 156-164
    • Basta-Kaim, A.1    Budziszewska, B.2    Jaworska-Feil, L.3    Tetich, M.4    Kubera, M.5    Leśkiewicz, M.6    Lasoń, W.7


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