Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression

NeuroImage

Volumn 53, Issue 3, 2010, Pages 908-917

  Inkster, Becky ^a   Nichols, Thomas E ^a   Saemann, Philipp G ^b   Auer, Dorothee P ^b   Holsboer, Florian ^b   Muglia, Pierandrea ^c   Matthews, Paul M ^a,d  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^c GSK   (Italy)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Depression; GSK3 substrates; Pathway analysis; Polymorphism; Voxel based morphometry; Wnt signaling pathway

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; AXIN; AXIN 2; BENZODIAZEPINE; DISHEVELLED 2; FRIZZLED 3 PROTEIN; FRIZZLED PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; HYPNOTIC AGENT; LITHIUM; LYMPHOID ENHANCER FACTOR 1; MOOD STABILIZER; NEUROLEPTIC AGENT; SEROTONIN UPTAKE INHIBITOR; TRANSCRIPTION FACTOR EMX2; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; WNT PROTEIN; WNT7A PROTEIN;

ADULT; AGE DISTRIBUTION; ARTICLE; BRAIN REGION; BRAIN SIZE; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME SUBSTRATE; ETHNICITY; FEMALE; GENETIC ASSOCIATION; GENOTYPE; GRAY MATTER; HUMAN; IMAGE ANALYSIS; IMAGE QUALITY; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SEX DIFFERENCE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; VOXEL BASED MORPHOMETRY;

BRAIN MAPPING; DEPRESSIVE DISORDER, MAJOR; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 77956227380     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2010.02.065     Document Type: Article

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