Activation of the Wnt signaling pathway: A molecular mechanism for lithium action

Developmental Biology

Volumn 185, Issue 1, 1997, Pages 82-91

  Hedgepeth, Chester M ^a   Conrad, Leslee J ^a   Zhang, Jie ^a   Huang, Hui Chuan ^a   Lee, Virginia M Y ^a   Klein, Peter S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GLYCOGEN SYNTHASE; INOSITOL; LITHIUM; ONCOPROTEIN; PROTEIN KINASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; NONHUMAN; ONCOGENE C JUN; OOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; XENOPUS;

EID: 0031149476     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1997.8552     Document Type: Article

References (55)

1. Angel P., Karin M. The role of Jun, Fos, and the AP-1 complex in cell proliferation and transformation [Review]. Biochim. Biophys. Acta. 1072:1991;129-157.
2. Atack J. R., Cook S. M., Watt A. P., Fletcher S. R., Ragan C. I. In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330. J. Neurochem. 60:1993;652-658.
3. Ault K. T., Durmwicz G., Galione A., Harger P. L., Busa W. B. Modulation ofXenopus. Development. 122:1996;2033-2041.
4. Behrens J., von Kries J. P., Kuhl M., Bruhn L., Wedlich D., Grosschedl R., Birchmeier W. Functional interaction of β-catenin with the transcription factor LEF-1. Nature. 382:1996;638-642.
5. Berridge M. J., Downes C. P., Hanley M. R. Neural and developmental actions of lithium: A unifying hypothesis. Cell. 59:1989;411-419.
6. Boyle W. J., Smeal T., Defize L. H. K., Woodgett J. R., Karin M., Hunter T. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell. 64:1991;573-584.
7. Breckenridge L. J., Warren R. L., Warner A. E. Lithium inhibits morphogenesis of the nervous system but not neuronal differentiation inXenopus laevis. Development. 99:1987;353-370.
8. Bullock B. P., McNeil G. P., Dobner P. R. Synergistic induction of neurotensin gene transcription in PC12 cells parallels changes in AP-1 activity. Mol. Brain Res. 27:1994;232-242.
9. Busa W. B., Gimlich R. L. Lithium-induced teratogenesis in frog embryos prevented by a polyphosphoinositide cycle intermediate or a diacylglycerol analog. Dev. Biol. 132:1989;315-324.
10. Christian J. L., McMahon J. A., McMahon A. P., Moon R. T. Xwnt-8, aXenopus. Development. 111:1991;1045-1056.
11. Christian J. L., Moon R. T. Interactions between Xwnt-8 and Spemann organizer signaling pathways generate a dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev. 7:1993;13-28.
12. Cook D., Fry M. J., Hughes K., Sumathipala R., Woodgett J. R., Dale T. C. Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C. EMBO J. 15:1996;4526-4536.
13. Cooke J., Smith E. The restrictive effect of early exposure to lithium upon body pattern inXenopus. Development. 102:1988;85-99.
14. de Groot R. P., Auwerx J., Bourouis M., Sassone-Corsi P. Negative regulation of Jun/AP-1: Conserved function of glycogen synthase kinase 3 and theDrosophila. Oncogene. 7:1992;841-847.
15. Dominguez I., Itoh K., Sokol S. Y. Role of glycogen synthase kinase 3 beta as a negative regulator of dorsoventral axis formation inXenopus. Proc. Natl. Acad. Sci. USA. 92:1995;8498-8502.
16. Dong Z., Xu R., Kim J., Zhan S., Ma W., Colburn N., Kung H. AP-1/Jun is required for earlyXenopus. J. Biol. Chem. 271:1996;9942-9946.
17. Drayer A. L., Van der Kaay J., Mayr G. W., Van Haastert P. J. Role of phospholipase C inDictyostelium: EMBO J. 13:1994;1601-1609.
18. Fagatto F., Gumbiner B. Beta-catenin localization duringXenopus. Development. 120:1994;3667-3679.
19. Funayama N., Fagotto F., McCrea P., Gumbiner B. M. Embryonic axis induction by the armadillo repeat domain of beta-catenin: Evidence for intracellular signaling. J. Cell Biol. 128:1995;959-968.
20. Gilman A. G., Rall T. W., Nies A. S., Taylor P. The Pharmacological Basis of Therapeutics. 1990;Pergamon Press, New York.
21. Goedert M., Jakes R. Expression of separate isoforms of human tau protein: Correlation with the tau pattern in brain and effects on tubulin polymerization. EMBO J. 9:1990;4225-4230.
22. Hallcher L. M., Sherman W. R. The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain. J. Biol. Chem. 255:1980;10896-10901.
23. Hanger D. P., Hughes K., Woodgett J. R., Brion J.-P., Anderton B. H. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci. Lett. 147:1992;58-62.
24. Harwood A. J., Plyte S. E., Woodgett J., Strutt H., Kay R. R. Glycogen synthase kinase 3 regulates cell fate inDictyostelium. Cell. 80:1995;139-148.
25. He X., Saint-Jeannet J.-P., Woodgett J. R., Varmus H. E., Dawid I. B. Glycogen synthase kinase-3 and dorsoventral patterning inXenopus. Nature. 374:1995;617-622.
26. Heasman J., Crawford A., Goldstone K., Garner-Hamrick P., Gumbiner B., McCrea P., Kintner C., Noro C. Y., Wylie C. Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in earlyXenopus. Cell. 79:1994;791-803.
27. Horstadius S. Experimental Embryology of Echinoderms. 1973;Oxford Univ. Press, Oxford.
28. Jope R. S., Williams M. B. Lithium and brain signal transduction systems. Biochem. Pharmacol. 47:1994;429-441.
29. Kao K. R., Masui Y., Elinson R. P. Lithium-induced respecification of pattern inXenopus. Nature. 1986;371-373.
30. Klein P. S., Melton D. A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. USA. 93:1996;8455-8459.
31. Kosik K. S., Orecchio L. D., Binder L., Trojanowski J. Q., Lee V.-Y., Lee G. Epitopes that span the tau molecular are shared with paired helical filaments. Neuron. 7:1988;817-825.
32. Lee V. M.-Y. Disruption of the cytoskeleton in Alzheimer's disease [Review]. Curr. Opin. Neurobiol. 5:1995;663-668.
33. Lovestone S., Reynolds C. H., Latimer D., Davis D., Anderton B., Gallo J., Hanger D., Mulot S., Maeda Y. Influence of ionic conditions on cell differentiation and morphogenesis of the cellular slime molds. Dev. Growth Differ. 12:1970;217-227.
34. Mandelkow E.-M., Mandelkow E. Tau as a marker for Alzheimer's disease. TIBS. 18:1993;480-483.
35. Mandelkow E. M., Drewes G., Biernat J., Gustke N., Van L. J., Vandenheede J. R., Mandelkow E. Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau. FEBS Lett. 314:1992;315-321.
36. Manji H., Potter W., Lenox R. Signal transduction pathways: Molecular targets for lithium's actions. Arch. Gen. Psychiatry. 52:1995;531-543.
37. Marquardt B., Stabel S., Woodgett J. R., Miller C. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr. Biol. 4:1994;1077-1086.
38. Maslanski J. A., Leshko L., Busa W. B. Lithium-sensitive production of inositol phosphates during amphibian embryonic mesoderm induction. Science. 256:1992;243-245.
39. Miller J. R., Moon R. T. Signal transduction through β-catenin and specification of cell fate during embryogenesis. Genes Dev. 10:1996;2527-2539.
40. Molenaar M., van de Wetering M., Oosterwegel M., Peterson-Maduro J., Godsave S., Korinek V., Roose J., Destree O., Clevers H. XTcf-3 transcription factor mediates B-catenin-induced axis formation inXenopus. Cell. 86:1996;391-399.
41. Mulot S. F. C., Hughes K., Woodgett J. R., Anderton B. H., Hanger D. P. PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3β FEBS Lett. 349:1994;359-364.
42. Nikolakaki E., Coffer P. J., Hemelsoet R., Woodgett J. R., Defize L. H. K. Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells. Oncogene. 8:1993;833-840.
43. Otvos L., Feiner L., Lang E., Szendrei G. I., Goedert M., Lee V. M.-Y. Monoclonal antibody PHF-1 recognizes tau protein phosphorylated at serine residues 396 and 404. J. Neurosci. Res. 39:1994;669-673.
44. Peifer M., Sweeton D., Casey M., Wieschaus E. wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. Development. 120:1994;369-380.
45. Pierce S. B., Kimelman D. Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3. Development. 121:1995;755-765.
46. Plyte S. E., Hughes K., Nikolakaki E., Pulverer B. J., Woodgett J. R. Glycogen synthase kinase-3: Functions in oncogenesis and development. Biochim. Biophys. Acta. 1114:1992;147-162.
47. Schneider S., Steinbeisser H., Warga R. M., Hausen P. β-Catenin translocation into nuclei demarcates the dorsalizing centers in frog and fish embryos. Mech. Dev. 57:1996;191-198.
48. Smith L. D., Xu W., Varnold R. L. Oogenesis and oocyte isolation. Methods Cell Biol. 36:1994;45-58.
49. Sperber B. R., Leight S., Goedert M., Lee V. M.-Y. Glycogen synthase kinase-3β phosphorylates tau protein at multiple sites in intact cells. Neurosci. Lett. 197:1995;149-153.
50. Stambolic V., Reul L., Woodgett J. R. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr. Biol. 6:1996;1664-1668.
51. van Leeuwen F., Samos C. H., Nusse R. Biological activity of solublewinglessDrosophila. Nature. 368:1994;342-344.
52. Williams M. B., Jope R. S. Circadian variation in rat brain AP-1 DNA binding activity after cholinergic stimulation: Modulation by lithium. Psychopharmacology. 122:1995;363-368.
53. Yamaguchi Y., Shinagawa A. Marked alteration at midblastula transition in the effect of lithium on formation of the larval body pattern ofXenopus laevis. Dev. Growth Differ. 31:1989;531-541.
54. +. Proc. Natl. Acad. Sci. USA. 92:1995;5149-5153.
55. Yost C., Torres M., Miller J., Huang E., Kimelman D., Moon R. The axis-inducing activity, stability, and subcellular distribution of β-catenin is regulated inXenopus. Genes Dev. 10:1996;1443-1454.