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Volumn 28, Issue 10, 2007, Pages 518-525

The Frizzled family of unconventional G-protein-coupled receptors

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DISHEVELLED PROTEIN; FRIZZLED PROTEIN; G PROTEIN COUPLED RECEPTOR; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; PHOSPHOPROTEIN; WNT PROTEIN;

EID: 34748812548     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2007.09.001     Document Type: Review
Times cited : (190)

References (71)
  • 1
    • 34249797911 scopus 로고    scopus 로고
    • Wnt-Frizzled signalling and the many paths to neural development and adult brain homeostasis
    • Malaterre J., et al. Wnt-Frizzled signalling and the many paths to neural development and adult brain homeostasis. Front. Biosci. 12 (2007) 492-506
    • (2007) Front. Biosci. , vol.12 , pp. 492-506
    • Malaterre, J.1
  • 2
    • 33847199795 scopus 로고    scopus 로고
    • Wnt signaling and human diseases: what are the therapeutic implications?
    • Luo J., et al. Wnt signaling and human diseases: what are the therapeutic implications?. Lab. Invest. 87 (2007) 97-103
    • (2007) Lab. Invest. , vol.87 , pp. 97-103
    • Luo, J.1
  • 3
    • 0030265570 scopus 로고    scopus 로고
    • A frizzled homolog functions in a vertebrate Wnt signaling pathway
    • Yang-Snyder J., et al. A frizzled homolog functions in a vertebrate Wnt signaling pathway. Curr. Biol. 6 (1996) 1302-1306
    • (1996) Curr. Biol. , vol.6 , pp. 1302-1306
    • Yang-Snyder, J.1
  • 4
    • 0344464720 scopus 로고    scopus 로고
    • Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface
    • Nusse R. Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development 130 (2003) 5297-5305
    • (2003) Development , vol.130 , pp. 5297-5305
    • Nusse, R.1
  • 5
    • 12944308329 scopus 로고    scopus 로고
    • Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF
    • Yamamoto A., et al. Shisa promotes head formation through the inhibition of receptor protein maturation for the caudalizing factors, Wnt and FGF. Cell 120 (2005) 223-235
    • (2005) Cell , vol.120 , pp. 223-235
    • Yamamoto, A.1
  • 6
    • 22944457221 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLVI. G protein-coupled receptor list
    • Foord S.M., et al. International Union of Pharmacology. XLVI. G protein-coupled receptor list. Pharmacol. Rev. 57 (2005) 279-288
    • (2005) Pharmacol. Rev. , vol.57 , pp. 279-288
    • Foord, S.M.1
  • 7
    • 33747339465 scopus 로고    scopus 로고
    • Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors
    • Gordon M.D., and Nusse R. Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J. Biol. Chem. 281 (2006) 22429-22433
    • (2006) J. Biol. Chem. , vol.281 , pp. 22429-22433
    • Gordon, M.D.1    Nusse, R.2
  • 8
    • 33846396811 scopus 로고    scopus 로고
    • Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility
    • Seifert J.R., and Mlodzik M. Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility. Nat. Rev. Genet. 8 (2007) 126-138
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 126-138
    • Seifert, J.R.1    Mlodzik, M.2
  • 9
    • 0031456672 scopus 로고    scopus 로고
    • Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
    • Slusarski D.C., et al. Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature 390 (1997) 410-413
    • (1997) Nature , vol.390 , pp. 410-413
    • Slusarski, D.C.1
  • 10
    • 33750047472 scopus 로고    scopus 로고
    • Suppression of cyclic GMP-dependent protein kinase is essential to the Wnt/cGMP/Ca2+ pathway
    • Ma L., and Wang H.Y. Suppression of cyclic GMP-dependent protein kinase is essential to the Wnt/cGMP/Ca2+ pathway. J. Biol. Chem. 281 (2006) 30990-31001
    • (2006) J. Biol. Chem. , vol.281 , pp. 30990-31001
    • Ma, L.1    Wang, H.Y.2
  • 11
    • 24644499046 scopus 로고    scopus 로고
    • Wnt and calcium signaling: beta-catenin-independent pathways
    • Kohn A.D., and Moon R.T. Wnt and calcium signaling: beta-catenin-independent pathways. Cell Calcium 38 (2005) 439-446
    • (2005) Cell Calcium , vol.38 , pp. 439-446
    • Kohn, A.D.1    Moon, R.T.2
  • 12
    • 27744495867 scopus 로고    scopus 로고
    • SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor
    • Rodriguez J., et al. SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor. Nat. Neurosci. 8 (2005) 1301-1309
    • (2005) Nat. Neurosci. , vol.8 , pp. 1301-1309
    • Rodriguez, J.1
  • 13
    • 12144289950 scopus 로고    scopus 로고
    • Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair
    • Xu Q., et al. Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell 116 (2004) 883-895
    • (2004) Cell , vol.116 , pp. 883-895
    • Xu, Q.1
  • 14
    • 33947533683 scopus 로고    scopus 로고
    • Mutational analysis of Norrin-Frizzled4 recognition
    • Smallwood P.M., et al. Mutational analysis of Norrin-Frizzled4 recognition. J. Biol. Chem. 282 (2007) 4057-4068
    • (2007) J. Biol. Chem. , vol.282 , pp. 4057-4068
    • Smallwood, P.M.1
  • 15
    • 0033523005 scopus 로고    scopus 로고
    • Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling
    • Bafico A., et al. Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. J. Biol. Chem. 274 (1999) 16180-16187
    • (1999) J. Biol. Chem. , vol.274 , pp. 16180-16187
    • Bafico, A.1
  • 16
    • 33744964431 scopus 로고    scopus 로고
    • Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
    • Nam J.S., et al. Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J. Biol. Chem. 281 (2006) 13247-13257
    • (2006) J. Biol. Chem. , vol.281 , pp. 13247-13257
    • Nam, J.S.1
  • 17
    • 2542631834 scopus 로고    scopus 로고
    • Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex
    • Mercurio S., et al. Connective-tissue growth factor modulates WNT signalling and interacts with the WNT receptor complex. Development 131 (2004) 2137-2147
    • (2004) Development , vol.131 , pp. 2137-2147
    • Mercurio, S.1
  • 18
    • 0035811492 scopus 로고    scopus 로고
    • Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains
    • Dann C.E., et al. Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains. Nature 412 (2001) 86-90
    • (2001) Nature , vol.412 , pp. 86-90
    • Dann, C.E.1
  • 19
    • 1342332090 scopus 로고    scopus 로고
    • Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization
    • Kaykas A., et al. Mutant Frizzled 4 associated with vitreoretinopathy traps wild-type Frizzled in the endoplasmic reticulum by oligomerization. Nat. Cell Biol. 6 (2004) 52-58
    • (2004) Nat. Cell Biol. , vol.6 , pp. 52-58
    • Kaykas, A.1
  • 20
    • 27144533268 scopus 로고    scopus 로고
    • The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling
    • Povelones M., and Nusse R. The role of the cysteine-rich domain of Frizzled in Wingless-Armadillo signaling. EMBO J. 24 (2005) 3493-3503
    • (2005) EMBO J. , vol.24 , pp. 3493-3503
    • Povelones, M.1    Nusse, R.2
  • 21
    • 0033118334 scopus 로고    scopus 로고
    • Molecular tinkering of G protein-coupled receptors: an evolutionary success
    • Bockaert J., and Pin J.P. Molecular tinkering of G protein-coupled receptors: an evolutionary success. EMBO J. 18 (1999) 1723-1729
    • (1999) EMBO J. , vol.18 , pp. 1723-1729
    • Bockaert, J.1    Pin, J.P.2
  • 22
    • 33847019563 scopus 로고    scopus 로고
    • Multiplicity of the interactions of Wnt proteins and their receptors
    • Kikuchi A., et al. Multiplicity of the interactions of Wnt proteins and their receptors. Cell. Signal. 19 (2007) 659-671
    • (2007) Cell. Signal. , vol.19 , pp. 659-671
    • Kikuchi, A.1
  • 23
    • 0037737726 scopus 로고    scopus 로고
    • Wnt proteins are lipid-modified and can act as stem cell growth factors
    • Willert K., et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423 (2003) 448-452
    • (2003) Nature , vol.423 , pp. 448-452
    • Willert, K.1
  • 24
    • 15244360639 scopus 로고    scopus 로고
    • Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation
    • Schulte G., et al. Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. J. Neurochem. 92 (2005) 1550-1553
    • (2005) J. Neurochem. , vol.92 , pp. 1550-1553
    • Schulte, G.1
  • 25
    • 8444223093 scopus 로고    scopus 로고
    • Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP
    • Cong F., et al. Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP. Development 131 (2004) 5103-5115
    • (2004) Development , vol.131 , pp. 5103-5115
    • Cong, F.1
  • 26
    • 27744535862 scopus 로고    scopus 로고
    • The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity
    • Wallingford J.B., and Habas R. The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development 132 (2005) 4421-4436
    • (2005) Development , vol.132 , pp. 4421-4436
    • Wallingford, J.B.1    Habas, R.2
  • 27
    • 33645888429 scopus 로고    scopus 로고
    • Dishevelled: a mobile scaffold catalyzing development
    • Malbon C.C., and Wang H.Y. Dishevelled: a mobile scaffold catalyzing development. Curr. Top. Dev. Biol. 72 (2006) 153-166
    • (2006) Curr. Top. Dev. Biol. , vol.72 , pp. 153-166
    • Malbon, C.C.1    Wang, H.Y.2
  • 28
    • 0344413477 scopus 로고    scopus 로고
    • Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
    • Wong H.C., et al. Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol. Cell 12 (2003) 1251-1260
    • (2003) Mol. Cell , vol.12 , pp. 1251-1260
    • Wong, H.C.1
  • 29
    • 2442680430 scopus 로고    scopus 로고
    • Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin
    • González-Sancho J.M., et al. Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin. Mol. Cell. Biol. 24 (2004) 4757-4768
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4757-4768
    • González-Sancho, J.M.1
  • 30
    • 0033598401 scopus 로고    scopus 로고
    • Casein kinase I transduces Wnt signals
    • Peters J.M., et al. Casein kinase I transduces Wnt signals. Nature 401 (1999) 345-350
    • (1999) Nature , vol.401 , pp. 345-350
    • Peters, J.M.1
  • 31
    • 0030973456 scopus 로고    scopus 로고
    • Casein kinase 2 associates with and phosphorylates dishevelled
    • Willert K., et al. Casein kinase 2 associates with and phosphorylates dishevelled. EMBO J. 16 (1997) 3089-3096
    • (1997) EMBO J. , vol.16 , pp. 3089-3096
    • Willert, K.1
  • 32
    • 19944372081 scopus 로고    scopus 로고
    • Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development
    • Ossipova O., et al. Distinct PAR-1 proteins function in different branches of Wnt signaling during vertebrate development. Dev. Cell 8 (2005) 829-841
    • (2005) Dev. Cell , vol.8 , pp. 829-841
    • Ossipova, O.1
  • 33
    • 0041470133 scopus 로고    scopus 로고
    • Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
    • Chen W., et al. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science 301 (2003) 1391-1394
    • (2003) Science , vol.301 , pp. 1391-1394
    • Chen, W.1
  • 34
    • 33748192514 scopus 로고    scopus 로고
    • Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis
    • Kibardin A., et al. Metastasis-associated kinase modulates Wnt signaling to regulate brain patterning and morphogenesis. Development 133 (2006) 2845-2854
    • (2006) Development , vol.133 , pp. 2845-2854
    • Kibardin, A.1
  • 35
    • 33846235822 scopus 로고    scopus 로고
    • Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin
    • Bryja V., et al. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell. Signal. 19 (2007) 610-616
    • (2007) Cell. Signal. , vol.19 , pp. 610-616
    • Bryja, V.1
  • 36
    • 33947312488 scopus 로고    scopus 로고
    • Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism
    • Bryja V., et al. Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J. Cell Sci. 120 (2007) 586-595
    • (2007) J. Cell Sci. , vol.120 , pp. 586-595
    • Bryja, V.1
  • 37
    • 33744962511 scopus 로고    scopus 로고
    • Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation
    • Swiatek W., et al. Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation. J. Biol. Chem. 281 (2006) 12233-12241
    • (2006) J. Biol. Chem. , vol.281 , pp. 12233-12241
    • Swiatek, W.1
  • 38
    • 0348013155 scopus 로고    scopus 로고
    • PP2A:B56epsilon is required for Wnt/beta-catenin signaling during embryonic development
    • Yang J., et al. PP2A:B56epsilon is required for Wnt/beta-catenin signaling during embryonic development. Development 130 (2003) 5569-5578
    • (2003) Development , vol.130 , pp. 5569-5578
    • Yang, J.1
  • 39
    • 33745865489 scopus 로고    scopus 로고
    • Casein kinase 2 Is activated and essential for Wnt/beta-catenin signaling
    • Gao Y., and Wang H.Y. Casein kinase 2 Is activated and essential for Wnt/beta-catenin signaling. J. Biol. Chem. 281 (2006) 18394-18400
    • (2006) J. Biol. Chem. , vol.281 , pp. 18394-18400
    • Gao, Y.1    Wang, H.Y.2
  • 40
    • 33845802651 scopus 로고    scopus 로고
    • Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation
    • Tu X., et al. Noncanonical Wnt signaling through G protein-linked PKCdelta activation promotes bone formation. Dev. Cell 12 (2007) 113-127
    • (2007) Dev. Cell , vol.12 , pp. 113-127
    • Tu, X.1
  • 41
    • 2442708165 scopus 로고    scopus 로고
    • Frizzleds: new members of the superfamily of G-protein-coupled receptors
    • Malbon C.C. Frizzleds: new members of the superfamily of G-protein-coupled receptors. Front. Biosci. 9 (2004) 1048-1058
    • (2004) Front. Biosci. , vol.9 , pp. 1048-1058
    • Malbon, C.C.1
  • 42
    • 33645096878 scopus 로고    scopus 로고
    • Structure-function analysis of Frizzleds
    • Wang H.Y., et al. Structure-function analysis of Frizzleds. Cell. Signal. 18 (2006) 934-941
    • (2006) Cell. Signal. , vol.18 , pp. 934-941
    • Wang, H.Y.1
  • 43
    • 2242453282 scopus 로고    scopus 로고
    • Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP
    • Ahumada A., et al. Signaling of rat Frizzled-2 through phosphodiesterase and cyclic GMP. Science 298 (2002) 2006-2010
    • (2002) Science , vol.298 , pp. 2006-2010
    • Ahumada, A.1
  • 44
    • 27844516613 scopus 로고    scopus 로고
    • Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins
    • Liu X., et al. Rapid, Wnt-induced changes in GSK3beta associations that regulate beta-catenin stabilization are mediated by Galpha proteins. Curr. Biol. 15 (2005) 1989-1997
    • (2005) Curr. Biol. , vol.15 , pp. 1989-1997
    • Liu, X.1
  • 45
    • 0036244913 scopus 로고    scopus 로고
    • The Frizzled-1/(beta(2))-adrenergic receptor chimera: pharmacological properties of a unique G protein-linked receptor
    • DeCostanzo A.J., et al. The Frizzled-1/(beta(2))-adrenergic receptor chimera: pharmacological properties of a unique G protein-linked receptor. Naunyn Schmiedebergs Arch. Pharmacol. 365 (2002) 341-348
    • (2002) Naunyn Schmiedebergs Arch. Pharmacol. , vol.365 , pp. 341-348
    • DeCostanzo, A.J.1
  • 46
    • 11844299003 scopus 로고    scopus 로고
    • Trimeric G protein-dependent frizzled signaling in Drosophila
    • Katanaev V.L., et al. Trimeric G protein-dependent frizzled signaling in Drosophila. Cell 120 (2005) 111-122
    • (2005) Cell , vol.120 , pp. 111-122
    • Katanaev, V.L.1
  • 47
    • 33646264327 scopus 로고    scopus 로고
    • Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila
    • Katanaev V.L., and Tomlinson A. Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 6524-6529
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 6524-6529
    • Katanaev, V.L.1    Tomlinson, A.2
  • 48
    • 0038360821 scopus 로고    scopus 로고
    • Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos
    • Sheldahl L.C., et al. Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos. J. Cell Biol. 161 (2003) 769-777
    • (2003) J. Cell Biol. , vol.161 , pp. 769-777
    • Sheldahl, L.C.1
  • 49
    • 33645714061 scopus 로고    scopus 로고
    • The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation
    • Angers S., et al. The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation. Nat. Cell Biol. 8 (2006) 348-357
    • (2006) Nat. Cell Biol. , vol.8 , pp. 348-357
    • Angers, S.1
  • 50
    • 33947401068 scopus 로고    scopus 로고
    • beta-Arrestins and cell signaling
    • Dewire S.M., et al. beta-Arrestins and cell signaling. Annu. Rev. Physiol. 69 (2007) 483-510
    • (2007) Annu. Rev. Physiol. , vol.69 , pp. 483-510
    • Dewire, S.M.1
  • 51
    • 34249856025 scopus 로고    scopus 로고
    • beta-Arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo
    • Bryja V., et al. beta-Arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 6690-6695
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 6690-6695
    • Bryja, V.1
  • 52
    • 34748861187 scopus 로고    scopus 로고
    • Regulation of Wnt signaling by receptor-mediated endocytosis
    • Kikuchi A., and Yamamoto H. Regulation of Wnt signaling by receptor-mediated endocytosis. J. Biochem. (Tokyo) 141 (2007) 443-451
    • (2007) J. Biochem. (Tokyo) , vol.141 , pp. 443-451
    • Kikuchi, A.1    Yamamoto, H.2
  • 53
    • 33746482870 scopus 로고    scopus 로고
    • Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin
    • Yamamoto H., et al. Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev. Cell 11 (2006) 213-223
    • (2006) Dev. Cell , vol.11 , pp. 213-223
    • Yamamoto, H.1
  • 54
    • 33746960721 scopus 로고    scopus 로고
    • A critical role for endocytosis in Wnt signaling
    • Blitzer J.T., and Nusse R. A critical role for endocytosis in Wnt signaling. BMC Cell Biol. 7 (2006) 28
    • (2006) BMC Cell Biol. , vol.7 , pp. 28
    • Blitzer, J.T.1    Nusse, R.2
  • 55
    • 34147165527 scopus 로고    scopus 로고
    • Inhibition of endocytosis blocks Wnt signalling to β-catenin by promoting dishevelled degradation
    • Bryja V., et al. Inhibition of endocytosis blocks Wnt signalling to β-catenin by promoting dishevelled degradation. Acta Physiol. (Oxf.) 190 (2007) 55-61
    • (2007) Acta Physiol. (Oxf.) , vol.190 , pp. 55-61
    • Bryja, V.1
  • 56
    • 33845875500 scopus 로고    scopus 로고
    • Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling
    • Yu A., et al. Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. Dev. Cell 12 (2007) 129-141
    • (2007) Dev. Cell , vol.12 , pp. 129-141
    • Yu, A.1
  • 57
    • 28144441697 scopus 로고    scopus 로고
    • Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2
    • Mathew D., et al. Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science 310 (2005) 1344-1347
    • (2005) Science , vol.310 , pp. 1344-1347
    • Mathew, D.1
  • 58
    • 4444262013 scopus 로고    scopus 로고
    • MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap
    • Yao R., et al. MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap. Oncogene 23 (2004) 6023-6030
    • (2004) Oncogene , vol.23 , pp. 6023-6030
    • Yao, R.1
  • 59
    • 0037134787 scopus 로고    scopus 로고
    • Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95
    • Hering H., and Sheng M. Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95. FEBS Lett. 521 (2002) 185-189
    • (2002) FEBS Lett. , vol.521 , pp. 185-189
    • Hering, H.1    Sheng, M.2
  • 60
    • 19344363080 scopus 로고    scopus 로고
    • The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye
    • Djiane A., et al. The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye. Cell 121 (2005) 621-631
    • (2005) Cell , vol.121 , pp. 621-631
    • Djiane, A.1
  • 61
    • 0034632672 scopus 로고    scopus 로고
    • The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain
    • Erdmann K.S., et al. The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain. Oncogene 19 (2000) 3894-3901
    • (2000) Oncogene , vol.19 , pp. 3894-3901
    • Erdmann, K.S.1
  • 62
    • 33746878216 scopus 로고    scopus 로고
    • Identification of a PDZ protein, PIST, as a binding partner for Rho effector Rhotekin: biochemical and cell-biological characterization of Rhotekin-PIST interaction
    • Ito H., et al. Identification of a PDZ protein, PIST, as a binding partner for Rho effector Rhotekin: biochemical and cell-biological characterization of Rhotekin-PIST interaction. Biochem. J. 397 (2006) 389-398
    • (2006) Biochem. J. , vol.397 , pp. 389-398
    • Ito, H.1
  • 63
    • 0028722697 scopus 로고
    • Rodbell and Gilman win 1994 Nobel Prize for Physiology and Medicine
    • Lefkowitz R.J. Rodbell and Gilman win 1994 Nobel Prize for Physiology and Medicine. Trends Pharmacol. Sci. 15 (1994) 442-444
    • (1994) Trends Pharmacol. Sci. , vol.15 , pp. 442-444
    • Lefkowitz, R.J.1
  • 64
    • 33644967242 scopus 로고    scopus 로고
    • Wnt signaling: complexity at the surface
    • Cadigan K.M., and Liu Y.I. Wnt signaling: complexity at the surface. J. Cell Sci. 119 (2006) 395-402
    • (2006) J. Cell Sci. , vol.119 , pp. 395-402
    • Cadigan, K.M.1    Liu, Y.I.2
  • 65
    • 2442663185 scopus 로고    scopus 로고
    • Specificity of WNT-receptor interactions
    • Hsieh J.C. Specificity of WNT-receptor interactions. Front. Biosci. 9 (2004) 1333-1338
    • (2004) Front. Biosci. , vol.9 , pp. 1333-1338
    • Hsieh, J.C.1
  • 66
    • 5044244757 scopus 로고    scopus 로고
    • R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis
    • Kazanskaya O., et al. R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. Dev. Cell 7 (2004) 525-534
    • (2004) Dev. Cell , vol.7 , pp. 525-534
    • Kazanskaya, O.1
  • 67
    • 33744964883 scopus 로고    scopus 로고
    • Phosphorylation of frizzled-3
    • Yanfeng W.A., et al. Phosphorylation of frizzled-3. J. Biol. Chem. 281 (2006) 11603-11609
    • (2006) J. Biol. Chem. , vol.281 , pp. 11603-11609
    • Yanfeng, W.A.1
  • 68
    • 0035957391 scopus 로고    scopus 로고
    • Regulation of eye development by frizzled signaling in Xenopus
    • Rasmussen J.T., et al. Regulation of eye development by frizzled signaling in Xenopus. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 3861-3866
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 3861-3866
    • Rasmussen, J.T.1
  • 69
    • 33646740793 scopus 로고    scopus 로고
    • Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP
    • Ataman B., et al. Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRIP. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 7841-7846
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 7841-7846
    • Ataman, B.1
  • 70
    • 23944441665 scopus 로고    scopus 로고
    • Reorganization of actin cytoskeleton by FRIED, a Frizzled-8 associated protein tyrosine phosphatase
    • Itoh K., et al. Reorganization of actin cytoskeleton by FRIED, a Frizzled-8 associated protein tyrosine phosphatase. Dev. Dyn. 234 (2005) 90-101
    • (2005) Dev. Dyn. , vol.234 , pp. 90-101
    • Itoh, K.1
  • 71
    • 0034812092 scopus 로고    scopus 로고
    • Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled
    • Yao R., et al. Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled. Biochem. Biophys. Res. Commun. 286 (2001) 771-778
    • (2001) Biochem. Biophys. Res. Commun. , vol.286 , pp. 771-778
    • Yao, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.