Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding

European Journal of Pharmacology

Volumn 650, Issue 2-3, 2011, Pages 621-628

  Bhuiyan, Md Shenuarin ^a   Tagashira, Hideaki ^a   Fukunaga, Kohji ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Endothelial nitric oxide synthase (eNOS); Myocardial hypertrophy; Protein kinase B (Akt); Sigma 1 receptor; Thoracic aorta

Indexed keywords

2 [4 METHOXY 3 (2 PHENYLETHOXY)PHENYL] N,N DIPROPYLETHYLAMINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUVOXAMINE MALEATE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PROTEIN KINASE C ALPHA; SERINE; SIGMA 1 OPIATE RECEPTOR;

ABDOMINAL AORTA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA INJURY; AORTA PRESSURE; AORTA STENOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; HEART HYPERTROPHY; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION; THORACIC AORTA; TREATMENT DURATION; WISTAR RAT;

ANIMALS; ANISOLES; AORTA, ABDOMINAL; AORTA, THORACIC; AORTIC VALVE STENOSIS; CARDIOMEGALY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLUVOXAMINE; NITRIC OXIDE SYNTHASE TYPE III; OVARIECTOMY; PHOSPHORYLATION; PROPYLAMINES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECEPTORS, SIGMA; SEROTONIN UPTAKE INHIBITORS; SIGNAL TRANSDUCTION;

EID: 78651066495     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.10.055     Document Type: Article

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