The roles of BDNF, pCREB and wnt3a in the latent period preceding activation of progenitor cell mitosis in the adult dentate Gyrus by fluoxetine

PLoS ONE

Volumn 5, Issue 10, 2010, Pages

  Pinnock, Scarlett B ^a   Blake, Alastair M ^a   Platt, Nicola J ^a   Herbert, Joe ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FLUOXETINE; K 252A; KI 67 ANTIGEN; TYROSINE KINASE RECEPTOR; WNT3A PROTEIN; CARBAZOLE DERIVATIVE; INDOLE ALKALOID; K 252; MESSENGER RNA; SEROTONIN UPTAKE INHIBITOR; WNT PROTEIN; WNT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COUNT; CELL LABELING; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; DENTATE GYRUS; DRUG MECHANISM; DRUG RECEPTOR BINDING; LATENT PERIOD; MALE; MITOSIS; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; STEM CELL; ANIMAL; CYTOLOGY; DRUG EFFECT; GENETICS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; PHYSIOLOGY; RAT;

RATTUS;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CARBAZOLES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DENTATE GYRUS; FLUOXETINE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INDOLE ALKALOIDS; MITOSIS; RATS; RNA, MESSENGER; SEROTONIN UPTAKE INHIBITORS; STEM CELLS; WNT PROTEINS;

EID: 78149426142     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013652     Document Type: Article

References (47)

1. Clelland CD, Choi M, Romberg C, Clemenson GD Jr, Fragniere A, et al. (2009) A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 325: 210-213.
2. Cuppini R, Bucherelli C, Ambrogini P, Ciuffoli S, Orsini L, et al. (2006) Agerelated naturally occurring depression of hippocampal neurogenesis does not affect trace fear conditioning. Hippocampus 16: 141-148.
3. Jessberger S, Gage FH (2009) Fate plasticity of adult hippocampal progenitors: biological relevance and therapeutic use. Trends Pharmacol Sci 30: 61-65.
4. Shors TJ, Miesegaes G, Beylin A, Zhao M, Rydel T, et al. (2001) Neurogenesis in the adult is involved in the formation of trace memories. Nature 410: 372-376.
5. Tashiro A, Makino H, Gage FH (2007) Experience-specific functional modification of the dentate gyrus through adult neurogenesis: a critical period during an immature stage. J Neurosci 27: 3252-3259.
6. Zhao C, Deng W, Gage FH (2008) Mechanisms and functional implications of adult neurogenesis. Cell 132: 645-660.
7. Gass P, Riva MA (2007) CREB, neurogenesis and depression. Bioessays 29: 957-961.
8. Jacobs BL, Praag H, Gage FH (2000) Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol Psychiatry 5: 262-269.
9. Nestler EJ, Barrot M, DiLeone RJ, Eisch AJ, Gold SJ, et al. (2002) Neurobiology of depression. Neuron 34: 13-25.
10. Boldrini M, Underwood MD, Hen R, Rosoklija GB, Dwork AJ, et al. (2009) Antidepressants increase neural progenitor cells in the human hippocampus. Neuropsychopharmacology 34: 2376-2389.
11. Muller MB, Lucassen PJ, Yassouridis A, Hoogendijk WJ, Holsboer F, et al. (2001) Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus. Eur J Neurosci 14: 1603-1612.
12. Malberg JE, Eisch AJ, Nestler EJ, Duman RS (2000) Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20: 9104-9110.
13. Santarelli L, Saxe M, Gross C, Surget A, Battaglia F, et al. (2003) Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301: 805-809.
14. Holick KA, Lee DC, Hen R, Dulawa SC (2008) Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor. Neuropsychopharmacology 33: 406-417.
15. Malberg JE, Schechter LE (2005) Increasing hippocampal neurogenesis: a novel mechanism for antidepressant drugs. Curr Pharm Des 11: 145-155.
16. Nibuya M, Morinobu S, Duman RS (1995) Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 15: 7539-7547.
17. Tsankova NM, Berton O, Renthal W, Kumar A, Neve RL, et al. (2006) Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci 9: 519-525.
18. De Foubert G, Carney SL, Robinson CS, Destexhe EJ, Tomlinson R, et al. (2004) Fluoxetine-induced change in rat brain expression of brain-derived neurotrophic factor varies depending on length of treatment. Neuroscience 128: 597-604.
19. Russo-Neustadt AA, Chen MJ (2005) Brain-derived neurotrophic factor and antidepressant activity. Curr Pharm Des 11: 1495-1510.
20. Saarelainen T, Hendolin P, Lucas G, Koponen E, Sairanen M, et al. (2003) Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. J Neurosci 23: 349-357.
21. Favaro R, Valotta M, Ferri AL, Latorre E, Mariani J, et al. (2009) Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh. Nat Neurosci 12: 1248-1256.
22. Lie DC, Colamarino SA, Song HJ, Desire L, Mira H, et al. (2005) Wnt signaling regulates adult hippocampal neurogenesis. Nature 437: 1370-1375.
23. Paxinos G, Watson CR (1998) The Rat Brain in Sterotaxic Coordinates: NewYork: Academic Press.
24. Liang FQ, Allen G, Earnest D (2000) Role of brain-derived neurotrophic factor in the circadian regulation of the suprachiasmatic pacemaker by light. J Neurosci 20: 2978-2987.
25. Al-Majed AA, Brushart TM, Gordon T (2000) Electrical stimulation accelerates and increases expression of BDNF and trkB mRNA in regenerating rat femoral motoneurons. Eur J Neurosci 12: 4381-4390.
26. Wong EY, Herbert J (2004) The corticoid environment: a determining factor for neural progenitors' survival in the adult hippocampus. Eur J Neurosci 20: 2491-2498.
27. Pinnock SB, Balendra R, Chan M, Hunt LT, Turner-Stokes T, et al. (2007) Interactions between nitric oxide and corticosterone in the regulation of progenitor cell proliferation in the dentate gyrus of the adult rat. Neuropsychopharmacology 32: 493-504.
28. Bradley J, Sporns O (1999) BDNF-dependent enhancement of exocytosis in cultured cortical neurons requires translation but not transcription. Brain Res 815: 140-149.
29. Lazarovici P, Rasouly D, Friedman L, Tabekman R, Ovadia H, et al. (1996) K252a and staurosporine microbial alkaloid toxins as prototype of neurotropic drugs. Adv Exp Med Biol 391: 367-377.
30. Ross AH, McKinnon CA, Daou MC, Ratliff K, Wolf DE (1995) Differential biological effects of K252 kinase inhibitors are related to membrane solubility but not to permeability. J Neurochem 65: 2748-2756.
31. Benmansour S, Deltheil T, Piotrowski J, Nicolas L, Reperant C, et al. (2008) Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents. Eur J Pharmacol 587: 90-98.
32. Jagasia R, Steib K, Englberger E, Herold S, Faus-Kessler T, et al. (2009) GABAcAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus. J Neurosci 29: 7966-7977.
33. Davidson KC, Jamshidi P, Daly R, Hearn MT, Pera MF, et al. (2007) Wnt3a regulates survival, expansion, and maintenance of neural progenitors derived from human embryonic stem cells. Mol Cell Neurosci 36: 408-415.
34. Solberg N, Machon O, Krauss S (2008) Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool. Dev Dyn 237: 1799-1811.
35. Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka K, et al. (2008) Behavioral and serotonergic consequences of decreasing or increasing hippocampus brainderived neurotrophic factor protein levels in mice. Neuropharmacology 55: 1006-1014.
36. Monteggia LM, Barrot M, Powell CM, Berton O, Galanis V, et al. (2004) Essential role of brain-derived neurotrophic factor in adult hippocampal function. Proc Natl Acad Sci U S A 101: 10827-10832.
37. Huang GJ, Bannerman D, Flint J (2008) Chronic fluoxetine treatment alters behavior, but not adult hippocampal neurogenesis, in BALB/cJ mice. Mol Psychiatry 13: 119-121.
38. Huang GJ, Herbert J (2005) The role of 5-HT1A receptors in the proliferation and survival of progenitor cells in the dentate gyrus of the adult hippocampus and their regulation by corticoids. Neuroscience 135: 803-813.
39. Pinnock SB, Herbert J (2008) Brain-derived neurotropic factor and neurogenesisin the adult rat dentate gyrus: interactions with corticosterone. Eur J Neurosci 27: 2493-2500.
40. Huang GJ, Herbert J (2006) Stimulation of neurogenesis in the hippocampus of the adult rat by fluoxetine requires rhythmic change in corticosterone. Biol Psychiatry 59: 619-624.
41. Wong EY, Herbert J (2005) Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus. Eur J Neurosci 22: 785-792.
42. Wong EY, Herbert J (2006) Raised circulating corticosterone inhibits neuronal differentiation of progenitor cells in the adult hippocampus. Neuroscience 137: 83-92.
43. Inestrosa NC, Arenas E (2010) Emerging roles of Wnts in the adult nervous system. Nat Rev Neurosci 11: 77-86.
44. Li G, Pleasure SJ (2005) Morphogenesis of the dentate gyrus: what we are learning from mouse mutants. Dev Neurosci 27: 93-99.
45. Balu DT, Hodes GE, Anderson BT, Lucki I (2009) Enhanced sensitivity of the MRL/MpJ mouse to the neuroplastic and behavioral effects of chronic antidepressant treatments. Neuropsychopharmacology 34: 1764-1773.
46. Maya Vetencourt JF, Sale A, Viegi A, Baroncelli L, De Pasquale R, et al. (2008) The antidepressant fluoxetine restores plasticity in the adult visual cortex. Science 320: 385-388.
47. Varea E, Blasco-Ibanez JM, Gomez-Climent MA, Castillo-Gomez E, Crespo C, et al. (2007) Chronic fluoxetine treatment increases the expression of PSANCAM in the medial prefrontal cortex. Neuropsychopharmacology 32: 803-812.