메뉴 건너뛰기




Volumn 4, Issue 5, 2004, Pages 259-272

Molecular effects of lithium

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ADENYLATE CYCLASE; AMPHETAMINE; ANTICONVULSIVE AGENT; ARACHIDONIC ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; CARBAMAZEPINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; FRUCTOSE BISPHOSPHATASE; GLYCOGEN SYNTHASE KINASE 3; INDOMETACIN; INOSITOL; INOSITOL PHOSPHATE; INOSITOL POLYPHOSPHATE; LITHIUM; MARCKS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NEUROLEPTIC AGENT; NUCLEOTIDASE; PHOSPHATIDYLINOSITIDE; PHOSPHOGLUCOMUTASE; PIROXICAM; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; TAMOXIFEN; UNINDEXED DRUG; VALPROIC ACID;

EID: 7244239296     PISSN: 15340384     EISSN: None     Source Type: Journal    
DOI: 10.1124/mi.4.5.6     Document Type: Review
Times cited : (178)

References (154)
  • 1
    • 4243137799 scopus 로고    scopus 로고
    • The course of bipolar disorder and the nature of agitated depression
    • Goodwin, F.K. and Ghaemi, S.N. The course of bipolar disorder and the nature of agitated depression. Am. J. Psychiatry 160, 2077-2079 (2003).
    • (2003) Am. J. Psychiatry , vol.160 , pp. 2077-2079
    • Goodwin, F.K.1    Ghaemi, S.N.2
  • 2
    • 0037219155 scopus 로고    scopus 로고
    • The prevalence and disability of bipolar spectrum disorders in the US population: Re-analysis of the ECA database taking into account subthreshold cases
    • Judd, L.L. and Akiskal, H.S. The prevalence and disability of bipolar spectrum disorders in the US population: Re-analysis of the ECA database taking into account subthreshold cases. J. Affect. Disord. 73, 123-131 (2003).
    • (2003) J. Affect. Disord. , vol.73 , pp. 123-131
    • Judd, L.L.1    Akiskal, H.S.2
  • 3
    • 0031001720 scopus 로고    scopus 로고
    • Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
    • Murray, C.J. and Lopez, A.D. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 349, 1498-1504 (1997).
    • (1997) Lancet , vol.349 , pp. 1498-1504
    • Murray, C.J.1    Lopez, A.D.2
  • 4
    • 0034717551 scopus 로고    scopus 로고
    • Association between depression and mortality in older adults: The Cardiovascular Health Study
    • Schulz, R., Beach, S.R., Ives, D.G., Martire, L.M., Ariyo, A.A., and Kop, W.J. Association between depression and mortality in older adults: The Cardiovascular Health Study. Arch. Intem. Med. 160 1761-1768 (2000).
    • (2000) Arch. Intem. Med. , vol.160 , pp. 1761-1768
    • Schulz, R.1    Beach, S.R.2    Ives, D.G.3    Martire, L.M.4    Ariyo, A.A.5    Kop, W.J.6
  • 5
    • 0031822289 scopus 로고    scopus 로고
    • The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment
    • Musselman, D.L., Evans, D.L., and Nemeroff, C.B. The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment. Arch. Gen. Psychiatry 55, 580-592 (1998).
    • (1998) Arch. Gen. Psychiatry , vol.55 , pp. 580-592
    • Musselman, D.L.1    Evans, D.L.2    Nemeroff, C.B.3
  • 6
    • 0141834950 scopus 로고    scopus 로고
    • Suicide risk in bipolar disorder during treatment with lithium and divalproex
    • Goodwin FK, Fireman B, Simon GE, Hunkeler EM, Lee J, Revicki D: Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA 290, 1467-1473 (2003).
    • (2003) JAMA , vol.290 , pp. 1467-1473
    • Goodwin, F.K.1    Fireman, B.2    Simon, G.E.3    Hunkeler, E.M.4    Lee, J.5    Revicki, D.6
  • 7
    • 0038642174 scopus 로고    scopus 로고
    • Lithium treatment and suicide risk in major affective disorders: Update and new findings
    • Baldessarini, R.J., Tondo, L., and Hennen, J. Lithium treatment and suicide risk in major affective disorders: Update and new findings. J. Clin. Psychiatry 64 Suppl. 5, 44-52 (2003).
    • (2003) J. Clin. Psychiatry , vol.64 , Issue.SUPPL. 5 , pp. 44-52
    • Baldessarini, R.J.1    Tondo, L.2    Hennen, J.3
  • 9
    • 0034805180 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
    • Ryves, W.J. and Harwood, A.J. Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem. Biophys. Res. Commun. 280, 720-725 (2001).
    • (2001) Biochem. Biophys. Res. Commun. , vol.280 , pp. 720-725
    • Ryves, W.J.1    Harwood, A.J.2
  • 11
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies, S.P., Reddy, H., Caivano, M., and Cohen, P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105 (2000).
    • (2000) Biochem. J. , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 12
    • 0029036695 scopus 로고
    • +-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure
    • +-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. Proc. Natl. Acad. Sci. U.S.A. 92, 5149-5153 (1995).
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 5149-5153
    • York, J.D.1    Ponder, J.W.2    Majerus, P.W.3
  • 13
    • 0033532046 scopus 로고    scopus 로고
    • Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3′-nucleotidase inhibited by inositol 1,4 bisphosphate
    • Spiegelberg, B.D., Xiong, J.P., Smith, J.J., Gu, R.F, and York, J.D. Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3′-nucleotidase inhibited by inositol 1,4 bisphosphate. J. Biol. Chem. 274, 13619-13628 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 13619-13628
    • Spiegelberg, B.D.1    Xiong, J.P.2    Smith, J.J.3    Gu, R.F.4    York, J.D.5
  • 14
    • 0020044028 scopus 로고
    • Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose- 1,6-diphosphate levels in rat muscles, brain and liver
    • Nordenberg, J., Kaplansky, M., Beery, E., Klein, S., and Beitner, R. Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose- 1,6-diphosphate levels in rat muscles, brain and liver. Biochem. Pharmacol. 31, 1025-1031 (1982).
    • (1982) Biochem. Pharmacol. , vol.31 , pp. 1025-1031
    • Nordenberg, J.1    Kaplansky, M.2    Beery, E.3    Klein, S.4    Beitner, R.5
  • 15
    • 0021765663 scopus 로고
    • Enzyme-bound intermediates in the conversion of glucose 1-phosphate to glucose 6-phosphate by phosphoglucomutase. Phosphorus NMR studies
    • Rhyu, G.I., Ray, W.J., Jr., and Markley, J.L. Enzyme-bound intermediates in the conversion of glucose 1-phosphate to glucose 6-phosphate by phosphoglucomutase. Phosphorus NMR studies. Biochemistry 23, 252-260 (1984).
    • (1984) Biochemistry , vol.23 , pp. 252-260
    • Rhyu, G.I.1    Ray Jr., W.J.2    Markley, J.L.3
  • 16
    • 0017861963 scopus 로고
    • The binding of lithium and of anionic metabolites to phosphoglucomutase
    • Ray, W.J., Jr., Szymanki, E.S., and Ng, L. The binding of lithium and of anionic metabolites to phosphoglucomutase. Biochim. Biophys. Acta 522, 434-442 (1978).
    • (1978) Biochim. Biophys. Acta , vol.522 , pp. 434-442
    • Ray Jr., W.J.1    Szymanki, E.S.2    Ng, L.3
  • 18
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein, P.S. and Melton, D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. U.S.A. 93, 8455-8459 (1996).
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 19
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells
    • Stambolic, V., Ruel, L., and Woodgett, J.R. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells. Curr. Biol. 6, 1664-1668 (1996).
    • (1996) Curr. Biol. , vol.6 , pp. 1664-1668
    • Stambolic, V.1    Ruel, L.2    Woodgett, J.R.3
  • 20
    • 1442284539 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3: A target for novel bipolar disorder treatments
    • Gould, T.D., Zarate, C.A., and Manji, H.K. Glycogen synthase kinase-3: A target for novel bipolar disorder treatments. J. Clin. Psychiatry 65, 10-21 (2004).
    • (2004) J. Clin. Psychiatry , vol.65 , pp. 10-21
    • Gould, T.D.1    Zarate, C.A.2    Manji, H.K.3
  • 21
    • 0026659202 scopus 로고
    • Inositol phosphate biochemistry
    • Majerus, P.W. Inositol phosphate biochemistry. Annu. Rev. Biochem. 61, 225-250 (1992).
    • (1992) Annu. Rev. Biochem. , vol.61 , pp. 225-250
    • Majerus, P.W.1
  • 22
    • 0036705074 scopus 로고    scopus 로고
    • Signaling networks in the pathophysiology and treatment of mood disorders
    • Gould, T.D. and Manji, H.K. Signaling networks in the pathophysiology and treatment of mood disorders. J. Psychosom. Res. 53, 687-697 (2002).
    • (2002) J. Psychosom. Res. , vol.53 , pp. 687-697
    • Gould, T.D.1    Manji, H.K.2
  • 24
    • 0016231591 scopus 로고
    • Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes
    • Naccarato, W.F., Ray, R.E., and Wells, W.W. Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes. Arch. Biochem. Biophys. 164, 194-201 (1974).
    • (1974) Arch. Biochem. Biophys. , vol.164 , pp. 194-201
    • Naccarato, W.F.1    Ray, R.E.2    Wells, W.W.3
  • 25
    • 0019127799 scopus 로고
    • The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain
    • Hallcher, L.M. and Sherman, W.R. The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain. J. Biol. Chem. 255, 10896-10901 (1980).
    • (1980) J. Biol. Chem. , vol.255 , pp. 10896-10901
    • Hallcher, L.M.1    Sherman, W.R.2
  • 26
    • 0023706194 scopus 로고
    • +-sensitive enzymes and proceeds via inositol 4-phosphate
    • +-sensitive enzymes and proceeds via inositol 4-phosphate. Biochem. J. 249, 143-148 (1988).
    • (1988) Biochem. J. , vol.249 , pp. 143-148
    • Ragan, C.I.1    Watling, K.J.2    Gee, N.S.3
  • 27
    • 0023705726 scopus 로고
    • Properties of inositol polyphosphate 1-phosphatase
    • Inhorn, R.C. and Majerus, P.W. Properties of inositol polyphosphate 1-phosphatase. J. Biol. Chem. 263, 14559-14565 (1988).
    • (1988) J. Biol. Chem. , vol.263 , pp. 14559-14565
    • Inhorn, R.C.1    Majerus, P.W.2
  • 28
    • 0024341795 scopus 로고
    • Neural and developmental actions of lithium: A unifying hypothesis
    • Berridge, M.J., Downes, C.P., and Hanley, M.R. Neural and developmental actions of lithium: A unifying hypothesis. Cell 59 411-419 (1989).
    • (1989) Cell , vol.59 , pp. 411-419
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 29
    • 0020465411 scopus 로고
    • Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands
    • Berridge, M.J., Downes, C.P., and Hanley, M.R. Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem. J. 206, 587-595 (1982).
    • (1982) Biochem. J. , vol.206 , pp. 587-595
    • Berridge, M.J.1    Downes, C.P.2    Hanley, M.R.3
  • 30
    • 0025912111 scopus 로고
    • Lithium and the phosphoinositide cycle: An example of uncompetitive inhibition and its pharmacological consequences
    • Nahorski, S.R., Ragan, C.I., and Challiss, R.A. Lithium and the phosphoinositide cycle: An example of uncompetitive inhibition and its pharmacological consequences. Trends Pharmacol. Sci. 12, 297-303 (1991).
    • (1991) Trends Pharmacol. Sci. , vol.12 , pp. 297-303
    • Nahorski, S.R.1    Ragan, C.I.2    Challiss, R.A.3
  • 31
    • 1942489264 scopus 로고    scopus 로고
    • Phosphoinositide deficiency due to inositol depletion is not a mechanism of lithium action in brain
    • Berry, G.T, Buccafusca, R., Greer, J.J., and Eccleston, E. Phosphoinositide deficiency due to inositol depletion is not a mechanism of lithium action in brain. Mol. Genet. Metab. 82, 87-92 (2004).
    • (2004) Mol. Genet. Metab. , vol.82 , pp. 87-92
    • Berry, G.T.1    Buccafusca, R.2    Greer, J.J.3    Eccleston, E.4
  • 32
    • 0015242494 scopus 로고
    • Reduced brain inositol in lithium-treated rats
    • Allison, J.H. and Stewart, M.A. Reduced brain inositol in lithium-treated rats. Nat. New Biol. 233, 267-268 (1971).
    • (1971) Nat. New Biol. , vol.233 , pp. 267-268
    • Allison, J.H.1    Stewart, M.A.2
  • 33
    • 0008836304 scopus 로고    scopus 로고
    • Lithium, phosphatidylinositol signaling, and bipolar disorder
    • Belmaker, R.H. (ed.) Washington, DC: American Psychiatric Press, Inc
    • Atack, J.R. Lithium, phosphatidylinositol signaling, and bipolar disorder. In: Bipolar medications: Mechanism of action. Belmaker, R.H. (ed.) Washington, DC: American Psychiatric Press, Inc. (2000).
    • (2000) Bipolar Medications: Mechanism of Action
    • Atack, J.R.1
  • 34
    • 0032744013 scopus 로고    scopus 로고
    • Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness
    • Moore, G.J., Bebchuk, J.M., Parrish, J.K., Faulk, M.W., Arfken, C.L., Strahl-Bevacqua, J., and Manji, H.K. Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness. Am. J. Psychiatry 156, 1902-1908 (1999).
    • (1999) Am. J. Psychiatry , vol.156 , pp. 1902-1908
    • Moore, G.J.1    Bebchuk, J.M.2    Parrish, J.K.3    Faulk, M.W.4    Arfken, C.L.5    Strahl-Bevacqua, J.6    Manji, H.K.7
  • 35
    • 0030898340 scopus 로고    scopus 로고
    • Inositol monophosphatase inhibitors - Lithium mimetics?
    • Atack, J.R. Inositol monophosphatase inhibitors - lithium mimetics? Med. Res. Rev. 17, 215-24 (1997).
    • (1997) Med. Res. Rev. , vol.17 , pp. 215-224
    • Atack, J.R.1
  • 36
    • 0027458537 scopus 로고
    • In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330
    • Atack, J.R., Cook, S.M., Watt, A.P., Fletcher, S.R., and Ragan, C.I. In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330. J. Neurochem. 60, 652-658 (1993).
    • (1993) J. Neurochem. , vol.60 , pp. 652-658
    • Atack, J.R.1    Cook, S.M.2    Watt, A.P.3    Fletcher, S.R.4    Ragan, C.I.5
  • 37
    • 0028339390 scopus 로고
    • Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers
    • Atack, J.R., Prior, A.M., Fletcher, S.R., Quirk, K., McKernan, R., and Ragan, C.I. Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers. J. Pharmacol. Exp. Ther. 270 70-76 (1994).
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , pp. 70-76
    • Atack, J.R.1    Prior, A.M.2    Fletcher, S.R.3    Quirk, K.4    McKernan, R.5    Ragan, C.I.6
  • 39
    • 0026493674 scopus 로고
    • Structure of inositol monophosphatase, the putative target of lithium therapy
    • Bone, R., Springer, J.P., and Atack, J.R. Structure of inositol monophosphatase, the putative target of lithium therapy. Proc. Natl. Acad. Sci. U.S.A. 89, 10031-10035 (1992).
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 10031-10035
    • Bone, R.1    Springer, J.P.2    Atack, J.R.3
  • 40
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • Frame, S. and Cohen, P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359, 1-16 (2001).
    • (2001) Biochem. J. , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 41
    • 0035909112 scopus 로고    scopus 로고
    • Judging a protein by more than its name: Gsk-3
    • Woodgett, J.R. Judging a protein by more than its name: Gsk-3. Sci. STKE RE12 (2001).
    • (2001) Sci. STKE RE12
    • Woodgett, J.R.1
  • 42
    • 0036788036 scopus 로고    scopus 로고
    • The wnt signaling pathway in bipolar disorder
    • Gould, T.D. and Manji, H.K. The wnt signaling pathway in bipolar disorder. Neuroscientist 8, 497-511 (2002).
    • (2002) Neuroscientist , vol.8 , pp. 497-511
    • Gould, T.D.1    Manji, H.K.2
  • 43
    • 0037042065 scopus 로고    scopus 로고
    • Endophenotypes in bipolar disorder
    • [Erratum in: Am. J. Med. Genet. 114, 592 (2002).]
    • Lenox, R.H., Gould, T.D., and Manji, H.K. Endophenotypes in bipolar disorder. Am. J. Med. Genet. 114, 391-406 (2002). [Erratum in: Am. J. Med. Genet. 114, 592 (2002).]
    • (2002) Am. J. Med. Genet. , vol.114 , pp. 391-406
    • Lenox, R.H.1    Gould, T.D.2    Manji, H.K.3
  • 44
    • 0036214603 scopus 로고    scopus 로고
    • Mood stabilizers, glycogen synthase kinase-3beta and cell survival
    • Jope, R.S. and Bijur, G.N. Mood stabilizers, glycogen synthase kinase-3beta and cell survival. Mol. Psychiatry 7 Suppl. 1, S35-S45 (2002).
    • (2002) Mol. Psychiatry , vol.7 , Issue.SUPPL. 1
    • Jope, R.S.1    Bijur, G.N.2
  • 45
    • 0032827466 scopus 로고    scopus 로고
    • Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?
    • Manji, H.K., Moore, G.J., and Chen, G. Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked? Biol Psychiatry 46, 929-40 (1999).
    • (1999) Biol Psychiatry , vol.46 , pp. 929-940
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 46
    • 4243165658 scopus 로고    scopus 로고
    • Emerging experimental therapeutics for bipolar disorder: Clues from the molecular pathophysiology
    • Quiroz, J.A., Singh, J., Gould, TD., Denicoff, K.D., Zarate, C.A., and Manji, H.K. Emerging experimental therapeutics for bipolar disorder: Clues from the molecular pathophysiology. Mol Psychiatry 9, 756-776 (2004).
    • (2004) Mol. Psychiatry , vol.9 , pp. 756-776
    • Quiroz, J.A.1    Singh, J.2    Gould, T.D.3    Denicoff, K.D.4    Zarate, C.A.5    Manji, H.K.6
  • 47
    • 0036116367 scopus 로고    scopus 로고
    • Neuroprotective effects of lithium in cultured cells and animal models of diseases
    • Chuang, D.M., Chen, R., Chalecka-Franaszek, E. et al. Neuroprotective effects of lithium in cultured cells and animal models of diseases. Bipolar Disord. 4, 129-136 (2002).
    • (2002) Bipolar. Disord. , vol.4 , pp. 129-136
    • Chuang, D.M.1    Chen, R.2    Chalecka-Franaszek, E.3
  • 48
    • 0022622039 scopus 로고
    • Lithium-induced respecification of pattern in Xenopus laevis embryos
    • Kao, K.R., Masui, Y., and Elinson, R.P. Lithium-induced respecification of pattern in Xenopus laevis embryos. Nature 322 371-373 (1986).
    • (1986) Nature , vol.322 , pp. 371-373
    • Kao, K.R.1    Masui, Y.2    Elinson, R.P.3
  • 49
    • 0028931511 scopus 로고
    • Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
    • He, X., Saint-Jeannet, J.P., Woodgett, J.R., Varmus, H.E., and Dawid, I.B. Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 375, 617-622 (1995).
    • (1995) Nature , vol.375 , pp. 617-622
    • He, X.1    Saint-Jeannet, J.P.2    Woodgett, J.R.3    Varmus, H.E.4    Dawid, I.B.5
  • 50
    • 0036810240 scopus 로고    scopus 로고
    • Lithium and valproic acid: Parallels and contrasts in diverse signaling contexts
    • Gurvich, N. and Klein, P.S. Lithium and valproic acid: Parallels and contrasts in diverse signaling contexts. Pharmacol. Ther. 96, 45-66 (2002).
    • (2002) Pharmacol. Ther. , vol.96 , pp. 45-66
    • Gurvich, N.1    Klein, P.S.2
  • 51
    • 0031567583 scopus 로고    scopus 로고
    • Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons
    • Munoz-Montano, J.R., Moreno, F.J., Avila, J., and Diaz-Nido, J. Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons. FEBS Lett. 411, 183-188 (1997).
    • (1997) FEBS Lett. , vol.411 , pp. 183-188
    • Munoz-Montano, J.R.1    Moreno, F.J.2    Avila, J.3    Diaz-Nido, J.4
  • 52
    • 0346688565 scopus 로고    scopus 로고
    • In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3
    • Gould, T.D., Chen, G., and Manji, H.K. In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 29, 32-38 (2004).
    • (2004) Neuropsychopharmacology , vol.29 , pp. 32-38
    • Gould, T.D.1    Chen, G.2    Manji, H.K.3
  • 53
    • 3342955475 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium
    • O'Brien, W.T., Harper, A.D., Jove, F, Woodgett, J.R., Maretto, S., Piccolo, S., and Klein, P.S. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J. Neurosci. 24, 6791-6798 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 6791-6798
    • O'Brien, W.T.1    Harper, A.D.2    Jove, F.3    Woodgett, J.R.4    Maretto, S.5    Piccolo, S.6    Klein, P.S.7
  • 54
    • 0038187674 scopus 로고    scopus 로고
    • GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
    • Phiel, C.J., Wilson, C.A., Lee, V.M., and Klein, P.S. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 423, 435-439 (2003).
    • (2003) Nature , vol.423 , pp. 435-439
    • Phiel, C.J.1    Wilson, C.A.2    Lee, V.M.3    Klein, P.S.4
  • 55
    • 0037087220 scopus 로고    scopus 로고
    • Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
    • Sun, X., Sato, S., Murayama, O., Murayama, M., Park, J.M., Yamaguchi, H., and Takashima, A. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 321, 61-64 (2002).
    • (2002) Neurosci. Lett. , vol.321 , pp. 61-64
    • Sun, X.1    Sato, S.2    Murayama, O.3    Murayama, M.4    Park, J.M.5    Yamaguchi, H.6    Takashima, A.7
  • 56
    • 2642552331 scopus 로고    scopus 로고
    • Lithium, a common drug for Bipolar Disorder treatment, regulates amyloid-β precursor protein processing
    • Su, Y., Ryder, J., Li, B. et al. Lithium, a common drug for Bipolar Disorder treatment, regulates amyloid-β precursor protein processing. Biochemistry 43, 6899-6908 (2004).
    • (2004) Biochemistry , vol.43 , pp. 6899-6908
    • Su, Y.1    Ryder, J.2    Li, B.3
  • 57
    • 1842420631 scopus 로고    scopus 로고
    • Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus
    • Kaidanovich-Beilin, O., Milman, A., Weizman, A., Pick, C.G., and Eldar-Finkelman, H. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus. Biol. Psychiatry 55, 781-784 (2004).
    • (2004) Biol. Psychiatry , vol.55 , pp. 781-784
    • Kaidanovich-Beilin, O.1    Milman, A.2    Weizman, A.3    Pick, C.G.4    Eldar-Finkelman, H.5
  • 58
    • 7244222408 scopus 로고    scopus 로고
    • AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
    • [Epub ahead of print] Jul
    • Gould, T.D., Einat, H., Bhat, R., and Manji, H.K. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int J. Neuropsychopharmacol. Jul 26, 1-4 (2004). [Epub ahead of print]
    • (2004) Int J. Neuropsychopharmacol. , vol.26 , pp. 1-4
    • Gould, T.D.1    Einat, H.2    Bhat, R.3    Manji, H.K.4
  • 59
    • 3242761438 scopus 로고    scopus 로고
    • In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain
    • Li, X., Zhu, W., Roh, M.S., Friedman, A.B., Rosborough, K., and Jope, R.S. In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain. Neuropsychopharmacology 29, 1426-1431 (2004).
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1426-1431
    • Li, X.1    Zhu, W.2    Roh, M.S.3    Friedman, A.B.4    Rosborough, K.5    Jope, R.S.6
  • 61
    • 0036398986 scopus 로고    scopus 로고
    • The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes
    • Kaidanovich, O. and Eldar-Finkelman, H. The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes. Expert Opin. Ther. Targets 6, 555-561 (2002).
    • (2002) Expert Opin. Ther. Targets , vol.6 , pp. 555-561
    • Kaidanovich, O.1    Eldar-Finkelman, H.2
  • 62
    • 0036769733 scopus 로고    scopus 로고
    • GSK3beta signalling: Casting a wide net in Alzheimer's disease
    • Bhat, R.V. and Budd, S.L. GSK3beta signalling: Casting a wide net in Alzheimer's disease. Neurosignals 11, 251-261 (2002 ).
    • (2002) Neurosignals , vol.11 , pp. 251-261
    • Bhat, R.V.1    Budd, S.L.2
  • 63
    • 0036276050 scopus 로고    scopus 로고
    • Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
    • Alvarez, G., Munoz-Montano, J.R., Satrustegui, J., Avila, J., Bogonez, E., and Diaz-Nido, J. Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord. 4 153-165 (2002).
    • (2002) Bipolar. Disord. , vol.4 , pp. 153-165
    • Alvarez, G.1    Munoz-Montano, J.R.2    Satrustegui, J.3    Avila, J.4    Bogonez, E.5    Diaz-Nido, J.6
  • 64
    • 2642552331 scopus 로고    scopus 로고
    • Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing
    • Su, Y., Ryder, J., Li, B. et al. Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing. Biochemistry 43, 6899-6908 (2004).
    • (2004) Biochemistry , vol.43 , pp. 6899-6908
    • Su, Y.1    Ryder, J.2    Li, B.3
  • 65
    • 0037040856 scopus 로고    scopus 로고
    • Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase - Dependent pathway is cardioprotective
    • Tong, H., Imahashi, K., Steenbergen, C., and Murphy, E. Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase - dependent pathway is cardioprotective. Circ. Res. 8, 377-379 (2002).
    • (2002) Circ. Res. , vol.8 , pp. 377-379
    • Tong, H.1    Imahashi, K.2    Steenbergen, C.3    Murphy, E.4
  • 66
    • 0035477020 scopus 로고    scopus 로고
    • GSK3 takes centre stage more than 20 years after its discovery
    • Frame, S., and Cohen, P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359, 1-16 (2001).
    • (2001) Biochem. J. , vol.359 , pp. 1-16
    • Frame, S.1    Cohen, P.2
  • 67
    • 0037609376 scopus 로고    scopus 로고
    • Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model
    • Ren, M., Senatorov, V.V., Chen, R.W, and Chuang, D.M. Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model. Proc. Natl. Acad. Sci. U.S.A. 100, 6210-6215 (2003).
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 6210-6215
    • Ren, M.1    Senatorov, V.V.2    Chen, R.W.3    Chuang, D.M.4
  • 68
    • 0034718421 scopus 로고    scopus 로고
    • Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration
    • Bhat, R.V., Shanley, J., Correll, M.R, Fieles, W.E., Keith, R.A., Scott, C.W., and Lee, C.M. Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration. Proc. Natl. Acad. Sci. U.S.A. 97, 11074-11079 (2000).
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 11074-11079
    • Bhat, R.V.1    Shanley, J.2    Correll, M.R.3    Fieles, W.E.4    Keith, R.A.5    Scott, C.W.6    Lee, C.M.7
  • 69
    • 0018972024 scopus 로고
    • Purification and properties of liver fructose 1,6-bisphosphatase from C57BL/KsJ normal and diabetic mice
    • Marcus, F. and Hosey, M.M. Purification and properties of liver fructose 1,6-bisphosphatase from C57BL/KsJ normal and diabetic mice. J. Biol. Chem. 255, 2481-2486 (1980).
    • (1980) J. Biol. Chem. , vol.255 , pp. 2481-2486
    • Marcus, F.1    Hosey, M.M.2
  • 70
    • 0017179353 scopus 로고
    • Size-dependent allosteric effects of monovalent cations on rabbit liver fructose- 1,6-bisphosphatase
    • Nakashima, K. and Tuboi, S. Size-dependent allosteric effects of monovalent cations on rabbit liver fructose- 1,6-bisphosphatase. J. Biol. Chem. 251, 4315-4321 (1976).
    • (1976) J. Biol. Chem. , vol.251 , pp. 4315-4321
    • Nakashima, K.1    Tuboi, S.2
  • 71
    • 0029088924 scopus 로고
    • Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase
    • Villeret, V., Huang, S., Fromm, H.J., and Lipscomb, W.N. Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase. Proc. Natl. Acad. Sci. U.S.A. 92, 8916-8920 (1995).
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 8916-8920
    • Villeret, V.1    Huang, S.2    Fromm, H.J.3    Lipscomb, W.N.4
  • 72
    • 0029980322 scopus 로고    scopus 로고
    • Kinetics and mechanisms of activation and inhibition of porcine liver fructose-1,6-bisphosphatase by monovalent cations
    • Zhang, R., Villeret, V., Lipscomb, W.N., and Fromm, H. Kinetics and mechanisms of activation and inhibition of porcine liver fructose-1,6-bisphosphatase by monovalent cations. Biochemistry 35, 3038-3043 (1996).
    • (1996) Biochemistry , vol.35 , pp. 3038-3043
    • Zhang, R.1    Villeret, V.2    Lipscomb, W.N.3    Fromm, H.4
  • 73
    • 0038778445 scopus 로고    scopus 로고
    • 3-(2-carboxyethyl)-4,6-dichloro-1 H-indole-2-carboxylic acid: An allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site
    • Wright, S.W., Carlo, A.A., Danley, D.E. et al. 3-(2-carboxyethyl)-4,6-dichloro-1 H-indole-2-carboxylic acid: An allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site. Bioorg. Med. Chem. Lett. 13, 2055-2058 (2003).
    • (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 2055-2058
    • Wright, S.W.1    Carlo, A.A.2    Danley, D.E.3
  • 74
    • 0039772523 scopus 로고    scopus 로고
    • A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3′-phosphoadenosine 5′-phosphate phosphatase and inositol-polyphosphate 1-phosphatase
    • Lopez-Coronado, J.M., Belles, J.M., Lesage, F., Serrano, R., and Rodriguez. P.L. A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3′-phosphoadenosine 5′-phosphate phosphatase and inositol-polyphosphate 1-phosphatase. J. Biol. Chem. 274, 16034-16039 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 16034-16039
    • Lopez-Coronado, J.M.1    Belles, J.M.2    Lesage, F.3    Serrano, R.4    Rodriguez, P.L.5
  • 76
    • 0036305698 scopus 로고    scopus 로고
    • Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3′-phosphoadenosine-5′-phosphate phosphatase activities: A novel target of lithium therapy
    • Patel, S., Yenush, L., Rodriguez, P.L., Serrano, R., and Blundell, T.L. Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3′-phosphoadenosine-5′-phosphate phosphatase activities: A novel target of lithium therapy. J. Mol. Biol. 315, 677-685 (2002).
    • (2002) J. Mol. Biol. , vol.315 , pp. 677-685
    • Patel, S.1    Yenush, L.2    Rodriguez, P.L.3    Serrano, R.4    Blundell, T.L.5
  • 77
    • 0041630998 scopus 로고    scopus 로고
    • Possible role of 3′(2′)-phosphoadenosine-5′-phosphate phosphatase in the etiology and therapy of bipolar disorder
    • Agam, G. and Shaltiel, G. Possible role of 3′(2′)-phosphoadenosine-5′-phosphate phosphatase in the etiology and therapy of bipolar disorder. Prog. Neuropsychopharm. Biol. Psych. 27, 723-727 (2003).
    • (2003) Prog. Neuropsychopharm. Biol. Psych. , vol.27 , pp. 723-727
    • Agam, G.1    Shaltiel, G.2
  • 78
    • 0036214671 scopus 로고    scopus 로고
    • Synaptic plasticity and mood disorders
    • Duman, R.S. Synaptic plasticity and mood disorders. Mol. Psychiatry 7 Suppl. 1, S29-S34 (2002).
    • (2002) Mol. Psychiatry , vol.7 , Issue.SUPPL. 1
    • Duman, R.S.1
  • 79
    • 0035295487 scopus 로고    scopus 로고
    • Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics. Psychopharmacol
    • Manji, H.K. and Duman, R.S. Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics. Psychopharmacol. Bull. 35, 5-49 (2001).
    • (2001) Bull. , vol.35 , pp. 5-49
    • Manji, H.K.1    Duman, R.S.2
  • 80
    • 0043240266 scopus 로고    scopus 로고
    • The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
    • Einat, H., Yuan, P., Gould, T.D., Li, J., Du, J., Zhang, L., Manji, H.K., and Chen, G. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J. Neurosci. 23, 7311-7316 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 7311-7316
    • Einat, H.1    Yuan, P.2    Gould, T.D.3    Li, J.4    Du, J.5    Zhang, L.6    Manji, H.K.7    Chen, G.8
  • 81
    • 0034795827 scopus 로고    scopus 로고
    • Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain
    • Fukumoto, T, Morinobu, S., Okamoto, Y., Kagaya, A., and Yamawaki, S. Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology (Berl.) 158, 100-106 (2001).
    • (2001) Psychopharmacology (Berl.) , vol.158 , pp. 100-106
    • Fukumoto, T.1    Morinobu, S.2    Okamoto, Y.3    Kagaya, A.4    Yamawaki, S.5
  • 82
    • 0141927282 scopus 로고    scopus 로고
    • Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line - Derived neurotrophic factor in a rat model of depression
    • Angelucci, F., Aloe, L., Jimenez-Vasquez, P., and Mathe, A.A. Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line - derived neurotrophic factor in a rat model of depression. Int. J. Neuropsychopharmacol. 6, 225-231 (2003).
    • (2003) Int. J. Neuropsychopharmacol. , vol.6 , pp. 225-231
    • Angelucci, F.1    Aloe, L.2    Jimenez-Vasquez, P.3    Mathe, A.A.4
  • 83
    • 0033013011 scopus 로고    scopus 로고
    • A bimodal model of the mechanism of action of lithium
    • Jope, R.S. A bimodal model of the mechanism of action of lithium. Mol. Psychiatry 4, 21-25 (1999).
    • (1999) Mol. Psychiatry , vol.4 , pp. 21-25
    • Jope, R.S.1
  • 84
    • 0031973757 scopus 로고    scopus 로고
    • Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin
    • Kofman, O., Li, P.P., and Warsh, J.J. Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin. Pharmacol. Biochem. Behav. 59, 191-200 (1998).
    • (1998) Pharmacol. Biochem. Behav. , vol.59 , pp. 191-200
    • Kofman, O.1    Li, P.P.2    Warsh, J.J.3
  • 85
    • 0018597959 scopus 로고
    • Changes in lymphocyte beta-adrenergic receptors in depression and mania
    • Extein, I., Tallman, J., Smith, C.C., and Goodwin, F.K. Changes in lymphocyte beta-adrenergic receptors in depression and mania. Psychiatry Res. 191-197 (1979).
    • (1979) Psychiatry Res. , pp. 191-197
    • Extein, I.1    Tallman, J.2    Smith, C.C.3    Goodwin, F.K.4
  • 86
    • 0022997635 scopus 로고
    • The cyclic AMP second messenger system in man: The effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification
    • Ebstein, R.P., Oppenheim, G., Ebstein, B.S., Amiri, Z., and Stessman, J. The cyclic AMP second messenger system in man: The effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification. Prog. Neuropsychopharmacol. Biol. Psychiatry 10 323-353 (1986).
    • (1986) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.10 , pp. 323-353
    • Ebstein, R.P.1    Oppenheim, G.2    Ebstein, B.S.3    Amiri, Z.4    Stessman, J.5
  • 89
    • 0038717215 scopus 로고    scopus 로고
    • Isoform-specific regulation of adenylyl cyclase: A potential target in future pharmacotherapy
    • Iwatsubo, K., Tsunematsu, T., and Ishikawa, Y. Isoform-specific regulation of adenylyl cyclase: A potential target in future pharmacotherapy. Expert Opin. Ther. Targets 7, 441-451 (2003).
    • (2003) Expert Opin. Ther. Targets , vol.7 , pp. 441-451
    • Iwatsubo, K.1    Tsunematsu, T.2    Ishikawa, Y.3
  • 90
    • 0034043203 scopus 로고    scopus 로고
    • CaM-kinases: Modulators of synaptic plasticity
    • Soderling, T.R. CaM-kinases: Modulators of synaptic plasticity. Curr. Opin. Neurobiol. 10, 375-380 (2000).
    • (2000) Curr. Opin. Neurobiol. , vol.10 , pp. 375-380
    • Soderling, T.R.1
  • 91
    • 0033570745 scopus 로고    scopus 로고
    • Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: Molecular transduction of mood stabilization in the treatment of manic-depressive illness
    • Manji, H.K. and Lenox, R.H. Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: Molecular transduction of mood stabilization in the treatment of manic-depressive illness. Biol. Psychiatry 46, 1328-1351 (1999).
    • (1999) Biol. Psychiatry , vol.46 , pp. 1328-1351
    • Manji, H.K.1    Lenox, R.H.2
  • 92
    • 0034209028 scopus 로고    scopus 로고
    • The high affinity inositol transport system - Implications for the pathophysiology and treatment of bipolar disorder
    • van Calker, D. and Belmaker, R.H. The high affinity inositol transport system - implications for the pathophysiology and treatment of bipolar disorder. Bipolar Disord. 2, 102-107 (2000).
    • (2000) Bipolar. Disord. , vol.2 , pp. 102-107
    • van Calker, D.1    Belmaker, R.H.2
  • 93
    • 0032864255 scopus 로고    scopus 로고
    • Inhibition of the high affinity myo-inositol transport system: A common mechanism of action of antibipolar drugs?
    • Lubrich, B. and van Calker, D. Inhibition of the high affinity myo-inositol transport system: A common mechanism of action of antibipolar drugs? Neuropsychopharmacology 21, 519-529 (1999).
    • (1999) Neuropsychopharmacology , vol.21 , pp. 519-529
    • Lubrich, B.1    van Calker, D.2
  • 94
    • 0037118050 scopus 로고    scopus 로고
    • A common mechanism of action for three mood-stabilizing drugs
    • Williams, R.S., Cheng, L., Mudge, A.W., and Harwood, A.J. A common mechanism of action for three mood-stabilizing drugs. Nature 417, 292-295 (2002).
    • (2002) Nature , vol.417 , pp. 292-295
    • Williams, R.S.1    Cheng, L.2    Mudge, A.W.3    Harwood, A.J.4
  • 95
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka, Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258, 607-614 (1992).
    • (1992) Science , vol.258 , pp. 607-614
    • Nishizuka, Y.1
  • 96
    • 0030272375 scopus 로고    scopus 로고
    • Modulation of protein kinase C isozymes and substrates by lithium: The role of myo-inositol
    • Manji, H.K., Bersudsky, Y., Chen, G., Belmaker, R.H., and Potter, W.Z. Modulation of protein kinase C isozymes and substrates by lithium: The role of myo-inositol. Neuropsychopharmacology 15 370-381 (1996).
    • (1996) Neuropsychopharmacology , vol.15 , pp. 370-381
    • Manji, H.K.1    Bersudsky, Y.2    Chen, G.3    Belmaker, R.H.4    Potter, W.Z.5
  • 97
    • 0027366278 scopus 로고
    • Lithium decreases membrane-associated protein kinase C in hippocampus: Selectivity for the alpha isozyme
    • Manji, H.K., Etcheberrigaray, R., Chen, G., and Olds, J.L. Lithium decreases membrane-associated protein kinase C in hippocampus: Selectivity for the alpha isozyme. J. Neurochem. 61, 2303-2310 (1993).
    • (1993) J. Neurochem. , vol.61 , pp. 2303-2310
    • Manji, H.K.1    Etcheberrigaray, R.2    Chen, G.3    Olds, J.L.4
  • 98
    • 0028850086 scopus 로고
    • Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells
    • Li, X. and Jope, R.S. Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells. J. Neurochem. 65, 2500-2508 (1995).
    • (1995) J. Neurochem. , vol.65 , pp. 2500-2508
    • Li, X.1    Jope, R.S.2
  • 99
    • 0026567408 scopus 로고
    • Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
    • Lenox, R.H., Watson, D.G., Patel, J., and Ellis, J. Chronic lithium administration alters a prominent PKC substrate in rat hippocampus. Brain Res. 570, 333-340 (1992).
    • (1992) Brain Res. , vol.570 , pp. 333-340
    • Lenox, R.H.1    Watson, D.G.2    Patel, J.3    Ellis, J.4
  • 100
    • 0030036555 scopus 로고    scopus 로고
    • Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: Potentiation by muscarinic receptor activation
    • Watson, D.G., and Lenox, R.H. Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: Potentiation by muscarinic receptor activation. J. Neurochem. 67, 767-777 (1996).
    • (1996) J. Neurochem. , vol.67 , pp. 767-777
    • Watson, D.G.1    Lenox, R.H.2
  • 101
    • 0026533049 scopus 로고
    • Sensitization, kindling, and carbamazepine: An update on their implications for the course of affective illness
    • Post, R.M., Susan, R., and Weiss, B. Sensitization, kindling, and carbamazepine: An update on their implications for the course of affective illness, in Pharmacopsychiatry 25, 41-43 (1992).
    • (1992) Pharmacopsychiatry , vol.25 , pp. 41-43
    • Post, R.M.1    Susan, R.2    Weiss, B.3
  • 102
  • 103
    • 0025776394 scopus 로고
    • Long-lasting enhancement of the membrane-associated protein kinase C activity in the hippocampal-kindled rat
    • Daigen, A., Akiyama, K., Itoh, T, Kohira, I., Sora, I., Morimoto, K., and Otsuki, S. Long-lasting enhancement of the membrane-associated protein kinase C activity in the hippocampal-kindled rat. Jpn. J. Psychiatry Neurol. 45, 297-301 (1991).
    • (1991) Jpn. J. Psychiatry Neurol. , vol.45 , pp. 297-301
    • Daigen, A.1    Akiyama, K.2    Itoh, T.3    Kohira, I.4    Sora, I.5    Morimoto, K.6    Otsuki, S.7
  • 105
    • 0028101999 scopus 로고
    • Kindled amygdaloid seizures in rats cause immediate and transient increase in protein kinase C activity followed by transient suppression of the activity
    • Osonoe, K., Ogata, S., Iwata, Y., and Mori, N. Kindled amygdaloid seizures in rats cause immediate and transient increase in protein kinase C activity followed by transient suppression of the activity. Epilepsia 35, 850-854 (1994).
    • (1994) Epilepsia , vol.35 , pp. 850-854
    • Osonoe, K.1    Ogata, S.2    Iwata, Y.3    Mori, N.4
  • 106
    • 0028068110 scopus 로고
    • Differential changes in the activities of multiple protein kinase C subspecies in the hippocampal-kindled rat
    • Ono, M., Akiyama, K., Tsutsui, K., and Kuroda, S. Differential changes in the activities of multiple protein kinase C subspecies in the hippocampal-kindled rat. Brain Res. 660, 27-33 (1994).
    • (1994) Brain Res. , vol.660 , pp. 27-33
    • Ono, M.1    Akiyama, K.2    Tsutsui, K.3    Kuroda, S.4
  • 107
    • 0029019938 scopus 로고
    • Long-lasting increase in protein kinase C activity in the hippocampus of amygdala-kindled rat
    • Akiyama, K., Ono, M., Kohira, I., Daigen, A., Ishihara, T., and Kuroda, S. Long-lasting increase in protein kinase C activity in the hippocampus of amygdala-kindled rat. Brain Res. 679, 212-220 (1995).
    • (1995) Brain Res. , vol.679 , pp. 212-220
    • Akiyama, K.1    Ono, M.2    Kohira, I.3    Daigen, A.4    Ishihara, T.5    Kuroda, S.6
  • 108
    • 0028846262 scopus 로고
    • Isozyme-specific changes in the expression of protein kinase C isozyme (alpha-zeta) genes in the hippocampus of rats induced by kindling epileptogenesis
    • Kamphuis, W., Hendriksen, E., and Lopes da Silva, F.H. Isozyme-specific changes in the expression of protein kinase C isozyme (alpha-zeta) genes in the hippocampus of rats induced by kindling epileptogenesis. Brain Res. 702, 94-100 (1995).
    • (1995) Brain Res. , vol.702 , pp. 94-100
    • Kamphuis, W.1    Hendriksen, E.2    Lopes da Silva, F.H.3
  • 109
    • 0026940934 scopus 로고
    • Amygdala kindling-induced seizures selectively impair spatial memory. 1. Behavioral characteristics and effects on hippocampal neuronal protein kinase C isoforms
    • Beldhuis, H.J., Everts, H.G, Van der Zee, E.A., Luiten, P.G., and Bohus, B. Amygdala kindling-induced seizures selectively impair spatial memory. 1. Behavioral characteristics and effects on hippocampal neuronal protein kinase C isoforms. Hippocampus 2, 397-409 (1992).
    • (1992) Hippocampus , vol.2 , pp. 397-409
    • Beldhuis, H.J.1    Everts, H.G.2    Van der Zee, E.A.3    Luiten, P.G.4    Bohus, B.5
  • 112
    • 0027221154 scopus 로고
    • Long-term increase in protein kinase C-gamma and muscarinic acetylcholine receptor expression in the cerebral cortex of amygdala-kindled rats - A quantitative immunocytochemical study
    • Beldhuis, H.J., De Ruiter, A.J., Maes, F.W., Suzuki, T, and Bohus, B. Long-term increase in protein kinase C-gamma and muscarinic acetylcholine receptor expression in the cerebral cortex of amygdala-kindled rats - a quantitative immunocytochemical study. Neuroscience 55, 965-973 (1993).
    • (1993) Neuroscience , vol.55 , pp. 965-973
    • Beldhuis, H.J.1    De Ruiter, A.J.2    Maes, F.W.3    Suzuki, T.4    Bohus, B.5
  • 113
    • 0026621687 scopus 로고
    • Protein kinase C and dopamine transport-2. Effects of amphetamine in vitro
    • Giambalvo, C.T. Protein kinase C and dopamine transport-2. Effects of amphetamine in vitro. Neuropharmacology 31, 1211-1222 (1992).
    • (1992) Neuropharmacology , vol.31 , pp. 1211-1222
    • Giambalvo, C.T.1
  • 114
    • 0026715630 scopus 로고
    • Protein kinase C and dopamine transport-1. Effects of amphetamine in vivo
    • Giambalvo, C.T. Protein kinase C and dopamine transport-1. Effects of amphetamine in vivo. Neuropharmacology, 31, 1201-1210 (1992).
    • (1992) Neuropharmacology , vol.31 , pp. 1201-1210
    • Giambalvo, C.T.1
  • 115
    • 0027385573 scopus 로고
    • Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine
    • Gnegy, M.E., Hong, P., and Ferrell, S.T. Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine. Brain Res. Mol. Brain Res. 20, 289-298 (1993).
    • (1993) Brain Res. Mol. Brain Res. , vol.20 , pp. 289-298
    • Gnegy, M.E.1    Hong, P.2    Ferrell, S.T.3
  • 116
    • 0031443572 scopus 로고    scopus 로고
    • Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine
    • Iwata, S.I., Hewlett, G.H., Ferrell, S.T., Kantor, L., and Gnegy, M.E. Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine. J. Pharmacol. Exp. Ther. 283, 1445-1452 (1997).
    • (1997) J. Pharmacol. Exp. Ther. , vol.283 , pp. 1445-1452
    • Iwata, S.I.1    Hewlett, G.H.2    Ferrell, S.T.3    Kantor, L.4    Gnegy, M.E.5
  • 117
    • 0030910710 scopus 로고    scopus 로고
    • Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes
    • Iwata, S., Hewlett, G.H., and Gnegy, M.E. Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes. Synapse 26, 281-291 (1997).
    • (1997) Synapse , vol.26 , pp. 281-291
    • Iwata, S.1    Hewlett, G.H.2    Gnegy, M.E.3
  • 118
    • 0031933722 scopus 로고    scopus 로고
    • Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices
    • Kantor, L. and Gnegy, M.E. Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices. J. Pharmacol. Exp. Ther. 284, 592-598 (1998).
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , pp. 592-598
    • Kantor, L.1    Gnegy, M.E.2
  • 119
    • 0027761105 scopus 로고
    • Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies
    • Steketee, J.D. Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies. Neuropharmacology 32, 1289-1297 (1993).
    • (1993) Neuropharmacology , vol.32 , pp. 1289-1297
    • Steketee, J.D.1
  • 120
    • 0028568329 scopus 로고
    • Intra-A10 injection of H7 blocks the development of sensitization to cocaine
    • Steketee, J.D. Intra-A10 injection of H7 blocks the development of sensitization to cocaine. Neuroreport 6, 69-72 (1994).
    • (1994) Neuroreport , vol.6 , pp. 69-72
    • Steketee, J.D.1
  • 122
    • 4243187646 scopus 로고    scopus 로고
    • Neurotrophic signaling in mood disorders
    • Gutkind, J.S. (ed.) Hoboken, NJ: John Wiley & Sons, Inc
    • Du, J., Gould, T.D., and Manji, H.K. Neurotrophic signaling in mood disorders. In: Signal Transduction and Human Disease. Gutkind, J.S. (ed.) Hoboken, NJ: John Wiley & Sons, Inc., 411-446 (2003).
    • (2003) Signal Transduction and Human Disease , pp. 411-446
    • Du, J.1    Gould, T.D.2    Manji, H.K.3
  • 123
    • 0036460741 scopus 로고    scopus 로고
    • Selective chronic stress-induced in vivo ERK1/2 hyperphosphorylation in medial prefrontocortical dendrites: Implications for stress-related cortical pathology?
    • Trentani, A., Kuipers, S.D., Ter Horst, G.J., and Den Boer, J.A. Selective chronic stress-induced in vivo ERK1/2 hyperphosphorylation in medial prefrontocortical dendrites: Implications for stress-related cortical pathology? Eur. J. Neurosci. 15, 1681-1691 (2002).
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 1681-1691
    • Trentani, A.1    Kuipers, S.D.2    Ter Horst, G.J.3    Den Boer, J.A.4
  • 125
    • 0035943699 scopus 로고    scopus 로고
    • The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
    • Yuan, P.X., Huang, L.D., Jiang, Y.M., Gutkind, J.S., Manji, H.K., and Chen, G. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J. Biol. Chem. 276, 31674-31683 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 31674-31683
    • Yuan, P.X.1    Huang, L.D.2    Jiang, Y.M.3    Gutkind, J.S.4    Manji, H.K.5    Chen, G.6
  • 126
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen, G., Zeng, W.Z., Yuan, P.X., Huang, L.D., Jiang, Y.M., Zhao, Z.H., and Manji, H.K. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J. Neurochem. 72, 879-882 (1999).
    • (1999) J. Neurochem. , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.Z.2    Yuan, P.X.3    Huang, L.D.4    Jiang, Y.M.5    Zhao, Z.H.6    Manji, H.K.7
  • 127
    • 0036220487 scopus 로고    scopus 로고
    • PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers
    • Manji, H.K. and Chen, G. PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers. Mol. Psychiatry 7 Suppl.1, S46-S56 (2002).
    • (2002) Mol. Psychiatry , vol.7 , Issue.SUPPL. 1
    • Manji, H.K.1    Chen, G.2
  • 128
    • 0035039841 scopus 로고    scopus 로고
    • Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: Long-term effects on cell survival and transcript stability
    • Chen, G., Huang, L.D., Zeng, W.Z., and Manji, H.K. Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: Long-term effects on cell survival and transcript stability. Int. J. Neuropsychopharmacol. 4, 47-64 (2001).
    • (2001) Int. J. Neuropsychopharmacol. , vol.4 , pp. 47-64
    • Chen, G.1    Huang, L.D.2    Zeng, W.Z.3    Manji, H.K.4
  • 129
    • 0034589368 scopus 로고    scopus 로고
    • Histopathology of the prefrontal cortex in major depression: What does it tell us about dysfunctional monoaminergic circuits?
    • Rajkowska, G. Histopathology of the prefrontal cortex in major depression: What does it tell us about dysfunctional monoaminergic circuits? Prog. Brain Res. 126, 397-412 (2000).
    • (2000) Prog. Brain Res. , vol.126 , pp. 397-412
    • Rajkowska, G.1
  • 130
    • 0037249456 scopus 로고    scopus 로고
    • Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism
    • Huang, X., Wu, D.Y., Chen, G., Manji, H., and Chen, D.F. Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism. Invest. Ophthalmol. Vis. Sci. 44, 347-354 (2003).
    • (2003) Invest. Ophthalmol. Vis. Sci. , vol.44 , pp. 347-354
    • Huang, X.1    Wu, D.Y.2    Chen, G.3    Manji, H.4    Chen, D.F.5
  • 131
    • 0036914074 scopus 로고    scopus 로고
    • Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity
    • Hashimoto, R., Takei, N., Shimazu, K., Christ, L., Lu, B., and Chuang, D.M. Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity. Neuropharmacology 43, 1173-1179 (2002).
    • (2002) Neuropharmacology , vol.43 , pp. 1173-1179
    • Hashimoto, R.1    Takei, N.2    Shimazu, K.3    Christ, L.4    Lu, B.5    Chuang, D.M.6
  • 133
    • 0036753235 scopus 로고    scopus 로고
    • Low glial numbers in the amygdala in major depressive disorder
    • Bowley, M.P., Drevets, W.C., Ongur, D., and Price, J.L. Low glial numbers in the amygdala in major depressive disorder. Biol. Psychiatry 52, 404-412 (2002).
    • (2002) Biol. Psychiatry , vol.52 , pp. 404-412
    • Bowley, M.P.1    Drevets, W.C.2    Ongur, D.3    Price, J.L.4
  • 134
    • 0028978925 scopus 로고
    • N-acetylaspartate in neuropsychiatric disorders
    • Tsai, G. and Coyle, J.T. N-acetylaspartate in neuropsychiatric disorders. Prog. Neurobiol. 46, 531-540 (1995).
    • (1995) Prog. Neurobiol. , vol.46 , pp. 531-540
    • Tsai, G.1    Coyle, J.T.2
  • 135
    • 18744435263 scopus 로고    scopus 로고
    • Lithium increases N-acetyl-aspartate in the human brain: In vivo evidence in support of bcl-2's neurotrophic effects?
    • Moore, G.J., Bebchuk, J.M., Hasanat, K. et al. Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects? Biol. Psychiatry 48, 1-8 (2000).
    • (2000) Biol. Psychiatry , vol.48 , pp. 1-8
    • Moore, G.J.1    Bebchuk, J.M.2    Hasanat, K.3
  • 136
    • 0034619037 scopus 로고    scopus 로고
    • Lithium-induced increase in human brain grey matter
    • Moore, G.J., Bebchuk, J.M., Wilds, I.B., Chen, G., and Manji, H.K. Lithium-induced increase in human brain grey matter. Lancet 356, 1241-1242 (2000).
    • (2000) Lancet , vol.356 , pp. 1241-1242
    • Moore, G.J.1    Bebchuk, J.M.2    Wilds, I.B.3    Chen, G.4    Manji, H.K.5
  • 138
    • 0346034866 scopus 로고    scopus 로고
    • Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients
    • Silverstone, P.H., Wu, R.H., O'Donnell, T., Ulrich, M., Asghar, S.J., and Hanstock, C.C. Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients. Int. Clin. Psychopharmacol. 18, 73-79 (2003).
    • (2003) Int. Clin. Psychopharmacol. , vol.18 , pp. 73-79
    • Silverstone, P.H.1    Wu, R.H.2    O'Donnell, T.3    Ulrich, M.4    Asghar, S.J.5    Hanstock, C.C.6
  • 139
    • 0023828843 scopus 로고
    • 2 via GTP-binding proteins: Arachidonic acid and its metabolites as second messengers
    • 2 via GTP-binding proteins: Arachidonic acid and its metabolites as second messengers. Trends Neurosci. 11, 117-123 (1988).
    • (1988) Trends Neurosci. , vol.11 , pp. 117-123
    • Axelrod, J.1    Burch, R.M.2    Jelsema, C.L.3
  • 140
    • 0034912915 scopus 로고    scopus 로고
    • In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling
    • Rapoport, S.I. In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling. J. Mol. Neurosci. 16, 243-261 (2001).
    • (2001) J. Mol. Neurosci. , vol.16 , pp. 243-261
    • Rapoport, S.I.1
  • 141
    • 0028985121 scopus 로고
    • Phospholipase A2 and G proteins
    • Axelrod, J. Phospholipase A2 and G proteins. Trends Neurosci. 18, 64-65 (1995).
    • (1995) Trends Neurosci. , vol.18 , pp. 64-65
    • Axelrod, J.1
  • 142
    • 0035010364 scopus 로고    scopus 로고
    • Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: A possible common effect of mood stabilizers
    • Chang, M.C., Contreras, M.A., Rosenberger, T.A., Rintala, J.J., Bell, J.M., and Rapoport, S.I. Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: A possible common effect of mood stabilizers. J. Neurochem. 77, 796-803 (2001).
    • (2001) J. Neurochem. , vol.77 , pp. 796-803
    • Chang, M.C.1    Contreras, M.A.2    Rosenberger, T.A.3    Rintala, J.J.4    Bell, J.M.5    Rapoport, S.I.6
  • 143
    • 0030596052 scopus 로고    scopus 로고
    • Lithium decreases turnover of arachidonate in several brain phospholipids
    • Erratum in: Neurosci. Lett. 222, 141 (1997)
    • Chang, M.C., Grange, E., Rabin, O., Bell, J.M., Allen, D.D., and Rapoport, S.I. Lithium decreases turnover of arachidonate in several brain phospholipids. Neurosci. Lett. 220, 171-174 (1996). Erratum in: Neurosci. Lett. 222, 141 (1997).
    • (1996) Neurosci. Lett. , vol.220 , pp. 171-174
    • Chang, M.C.1    Grange, E.2    Rabin, O.3    Bell, J.M.4    Allen, D.D.5    Rapoport, S.I.6
  • 144
    • 0036301389 scopus 로고    scopus 로고
    • Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?
    • Rapoport, S.I. and Bosetti, F. Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? Arch. Gen. Psychiatry 59, 592-596 (2002).
    • (2002) Arch. Gen. Psychiatry , vol.59 , pp. 592-596
    • Rapoport, S.I.1    Bosetti, F.2
  • 148
    • 0038673579 scopus 로고    scopus 로고
    • Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain
    • Bosetti, F., Weerasinghe, G.R., Rosenberger, T.A., and Rapoport, S.I. Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. J. Neurochem. 85, 690-696 (2003).
    • (2003) J. Neurochem. , vol.85 , pp. 690-696
    • Bosetti, F.1    Weerasinghe, G.R.2    Rosenberger, T.A.3    Rapoport, S.I.4
  • 153
    • 7244244784 scopus 로고    scopus 로고
    • March treatment trial grant
    • Stanley Medical Institute. www.stanleyresearch.org
    • Soares, J. and Bowden, C. March treatment trial grant. Stanley Medical Institute. www.stanleyresearch.org (2002).
    • (2002)
    • Soares, J.1    Bowden, C.2
  • 154
    • 4243196940 scopus 로고    scopus 로고
    • Emerging experimental therapeutics for bipolar disorder: Insights from the molecular and cellular actions of current mood stabilizers
    • Gould, T.D., Quiroz, J.A., Singh, J., Zarate, C.A., and Manji, H.K. Emerging experimental therapeutics for bipolar disorder: Insights from the molecular and cellular actions of current mood stabilizers. Mol. Psychiatry 9, 734-755 (2004).
    • (2004) Mol. Psychiatry , vol.9 , pp. 734-755
    • Gould, T.D.1    Quiroz, J.A.2    Singh, J.3    Zarate, C.A.4    Manji, H.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.