-
1
-
-
4243137799
-
The course of bipolar disorder and the nature of agitated depression
-
Goodwin, F.K. and Ghaemi, S.N. The course of bipolar disorder and the nature of agitated depression. Am. J. Psychiatry 160, 2077-2079 (2003).
-
(2003)
Am. J. Psychiatry
, vol.160
, pp. 2077-2079
-
-
Goodwin, F.K.1
Ghaemi, S.N.2
-
2
-
-
0037219155
-
The prevalence and disability of bipolar spectrum disorders in the US population: Re-analysis of the ECA database taking into account subthreshold cases
-
Judd, L.L. and Akiskal, H.S. The prevalence and disability of bipolar spectrum disorders in the US population: Re-analysis of the ECA database taking into account subthreshold cases. J. Affect. Disord. 73, 123-131 (2003).
-
(2003)
J. Affect. Disord.
, vol.73
, pp. 123-131
-
-
Judd, L.L.1
Akiskal, H.S.2
-
3
-
-
0031001720
-
Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study
-
Murray, C.J. and Lopez, A.D. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet 349, 1498-1504 (1997).
-
(1997)
Lancet
, vol.349
, pp. 1498-1504
-
-
Murray, C.J.1
Lopez, A.D.2
-
4
-
-
0034717551
-
Association between depression and mortality in older adults: The Cardiovascular Health Study
-
Schulz, R., Beach, S.R., Ives, D.G., Martire, L.M., Ariyo, A.A., and Kop, W.J. Association between depression and mortality in older adults: The Cardiovascular Health Study. Arch. Intem. Med. 160 1761-1768 (2000).
-
(2000)
Arch. Intem. Med.
, vol.160
, pp. 1761-1768
-
-
Schulz, R.1
Beach, S.R.2
Ives, D.G.3
Martire, L.M.4
Ariyo, A.A.5
Kop, W.J.6
-
5
-
-
0031822289
-
The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment
-
Musselman, D.L., Evans, D.L., and Nemeroff, C.B. The relationship of depression to cardiovascular disease: Epidemiology, biology, and treatment. Arch. Gen. Psychiatry 55, 580-592 (1998).
-
(1998)
Arch. Gen. Psychiatry
, vol.55
, pp. 580-592
-
-
Musselman, D.L.1
Evans, D.L.2
Nemeroff, C.B.3
-
6
-
-
0141834950
-
Suicide risk in bipolar disorder during treatment with lithium and divalproex
-
Goodwin FK, Fireman B, Simon GE, Hunkeler EM, Lee J, Revicki D: Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA 290, 1467-1473 (2003).
-
(2003)
JAMA
, vol.290
, pp. 1467-1473
-
-
Goodwin, F.K.1
Fireman, B.2
Simon, G.E.3
Hunkeler, E.M.4
Lee, J.5
Revicki, D.6
-
7
-
-
0038642174
-
Lithium treatment and suicide risk in major affective disorders: Update and new findings
-
Baldessarini, R.J., Tondo, L., and Hennen, J. Lithium treatment and suicide risk in major affective disorders: Update and new findings. J. Clin. Psychiatry 64 Suppl. 5, 44-52 (2003).
-
(2003)
J. Clin. Psychiatry
, vol.64
, Issue.SUPPL. 5
, pp. 44-52
-
-
Baldessarini, R.J.1
Tondo, L.2
Hennen, J.3
-
9
-
-
0034805180
-
Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
-
Ryves, W.J. and Harwood, A.J. Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem. Biophys. Res. Commun. 280, 720-725 (2001).
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 720-725
-
-
Ryves, W.J.1
Harwood, A.J.2
-
10
-
-
0036893028
-
Mood stabilizer psychopharmacology
-
Gould, T.D., Chen, G., and Manji, H.K. Mood stabilizer psychopharmacology. Clin. Neurosci. Res. 24, 193-212 (2002 ).
-
(2002)
Clin. Neurosci. Res.
, vol.24
, pp. 193-212
-
-
Gould, T.D.1
Chen, G.2
Manji, H.K.3
-
11
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S.P., Reddy, H., Caivano, M., and Cohen, P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105 (2000).
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
12
-
-
0029036695
-
+-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure
-
+-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure. Proc. Natl. Acad. Sci. U.S.A. 92, 5149-5153 (1995).
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 5149-5153
-
-
York, J.D.1
Ponder, J.W.2
Majerus, P.W.3
-
13
-
-
0033532046
-
Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3′-nucleotidase inhibited by inositol 1,4 bisphosphate
-
Spiegelberg, B.D., Xiong, J.P., Smith, J.J., Gu, R.F, and York, J.D. Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3′-nucleotidase inhibited by inositol 1,4 bisphosphate. J. Biol. Chem. 274, 13619-13628 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 13619-13628
-
-
Spiegelberg, B.D.1
Xiong, J.P.2
Smith, J.J.3
Gu, R.F.4
York, J.D.5
-
14
-
-
0020044028
-
Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose- 1,6-diphosphate levels in rat muscles, brain and liver
-
Nordenberg, J., Kaplansky, M., Beery, E., Klein, S., and Beitner, R. Effects of lithium on the activities of phosphofructokinase and phosphoglucomutase and on glucose- 1,6-diphosphate levels in rat muscles, brain and liver. Biochem. Pharmacol. 31, 1025-1031 (1982).
-
(1982)
Biochem. Pharmacol.
, vol.31
, pp. 1025-1031
-
-
Nordenberg, J.1
Kaplansky, M.2
Beery, E.3
Klein, S.4
Beitner, R.5
-
15
-
-
0021765663
-
Enzyme-bound intermediates in the conversion of glucose 1-phosphate to glucose 6-phosphate by phosphoglucomutase. Phosphorus NMR studies
-
Rhyu, G.I., Ray, W.J., Jr., and Markley, J.L. Enzyme-bound intermediates in the conversion of glucose 1-phosphate to glucose 6-phosphate by phosphoglucomutase. Phosphorus NMR studies. Biochemistry 23, 252-260 (1984).
-
(1984)
Biochemistry
, vol.23
, pp. 252-260
-
-
Rhyu, G.I.1
Ray Jr., W.J.2
Markley, J.L.3
-
16
-
-
0017861963
-
The binding of lithium and of anionic metabolites to phosphoglucomutase
-
Ray, W.J., Jr., Szymanki, E.S., and Ng, L. The binding of lithium and of anionic metabolites to phosphoglucomutase. Biochim. Biophys. Acta 522, 434-442 (1978).
-
(1978)
Biochim. Biophys. Acta
, vol.522
, pp. 434-442
-
-
Ray Jr., W.J.1
Szymanki, E.S.2
Ng, L.3
-
17
-
-
0035851179
-
Phosphoglucomutase is an in vivo lithium target in yeast
-
Masuda, C.A., Xavier, M.A., Mattos, K.A., Galina, A., and Montero-Lomeli, M. Phosphoglucomutase is an in vivo lithium target in yeast. J. Biol. Chem. 276, 37794-37801 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37794-37801
-
-
Masuda, C.A.1
Xavier, M.A.2
Mattos, K.A.3
Galina, A.4
Montero-Lomeli, M.5
-
18
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein, P.S. and Melton, D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. U.S.A. 93, 8455-8459 (1996).
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
19
-
-
0030449964
-
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells
-
Stambolic, V., Ruel, L., and Woodgett, J.R. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signaling in intact cells. Curr. Biol. 6, 1664-1668 (1996).
-
(1996)
Curr. Biol.
, vol.6
, pp. 1664-1668
-
-
Stambolic, V.1
Ruel, L.2
Woodgett, J.R.3
-
20
-
-
1442284539
-
Glycogen synthase kinase-3: A target for novel bipolar disorder treatments
-
Gould, T.D., Zarate, C.A., and Manji, H.K. Glycogen synthase kinase-3: A target for novel bipolar disorder treatments. J. Clin. Psychiatry 65, 10-21 (2004).
-
(2004)
J. Clin. Psychiatry
, vol.65
, pp. 10-21
-
-
Gould, T.D.1
Zarate, C.A.2
Manji, H.K.3
-
21
-
-
0026659202
-
Inositol phosphate biochemistry
-
Majerus, P.W. Inositol phosphate biochemistry. Annu. Rev. Biochem. 61, 225-250 (1992).
-
(1992)
Annu. Rev. Biochem.
, vol.61
, pp. 225-250
-
-
Majerus, P.W.1
-
22
-
-
0036705074
-
Signaling networks in the pathophysiology and treatment of mood disorders
-
Gould, T.D. and Manji, H.K. Signaling networks in the pathophysiology and treatment of mood disorders. J. Psychosom. Res. 53, 687-697 (2002).
-
(2002)
J. Psychosom. Res.
, vol.53
, pp. 687-697
-
-
Gould, T.D.1
Manji, H.K.2
-
23
-
-
0027158943
-
Lithium and myo-inositol homeostasis
-
Gani, D., Downes., C.P., Batty, I., and Bramham, J. Lithium and myo-inositol homeostasis. Biochim. Biophys. Acta 1177, 253-269 (1993).
-
(1993)
Biochim. Biophys. Acta
, vol.1177
, pp. 253-269
-
-
Gani, D.1
Downes, C.P.2
Batty, I.3
Bramham, J.4
-
24
-
-
0016231591
-
Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes
-
Naccarato, W.F., Ray, R.E., and Wells, W.W. Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes. Arch. Biochem. Biophys. 164, 194-201 (1974).
-
(1974)
Arch. Biochem. Biophys.
, vol.164
, pp. 194-201
-
-
Naccarato, W.F.1
Ray, R.E.2
Wells, W.W.3
-
25
-
-
0019127799
-
The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain
-
Hallcher, L.M. and Sherman, W.R. The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain. J. Biol. Chem. 255, 10896-10901 (1980).
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 10896-10901
-
-
Hallcher, L.M.1
Sherman, W.R.2
-
26
-
-
0023706194
-
+-sensitive enzymes and proceeds via inositol 4-phosphate
-
+-sensitive enzymes and proceeds via inositol 4-phosphate. Biochem. J. 249, 143-148 (1988).
-
(1988)
Biochem. J.
, vol.249
, pp. 143-148
-
-
Ragan, C.I.1
Watling, K.J.2
Gee, N.S.3
-
27
-
-
0023705726
-
Properties of inositol polyphosphate 1-phosphatase
-
Inhorn, R.C. and Majerus, P.W. Properties of inositol polyphosphate 1-phosphatase. J. Biol. Chem. 263, 14559-14565 (1988).
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 14559-14565
-
-
Inhorn, R.C.1
Majerus, P.W.2
-
28
-
-
0024341795
-
Neural and developmental actions of lithium: A unifying hypothesis
-
Berridge, M.J., Downes, C.P., and Hanley, M.R. Neural and developmental actions of lithium: A unifying hypothesis. Cell 59 411-419 (1989).
-
(1989)
Cell
, vol.59
, pp. 411-419
-
-
Berridge, M.J.1
Downes, C.P.2
Hanley, M.R.3
-
29
-
-
0020465411
-
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands
-
Berridge, M.J., Downes, C.P., and Hanley, M.R. Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem. J. 206, 587-595 (1982).
-
(1982)
Biochem. J.
, vol.206
, pp. 587-595
-
-
Berridge, M.J.1
Downes, C.P.2
Hanley, M.R.3
-
30
-
-
0025912111
-
Lithium and the phosphoinositide cycle: An example of uncompetitive inhibition and its pharmacological consequences
-
Nahorski, S.R., Ragan, C.I., and Challiss, R.A. Lithium and the phosphoinositide cycle: An example of uncompetitive inhibition and its pharmacological consequences. Trends Pharmacol. Sci. 12, 297-303 (1991).
-
(1991)
Trends Pharmacol. Sci.
, vol.12
, pp. 297-303
-
-
Nahorski, S.R.1
Ragan, C.I.2
Challiss, R.A.3
-
31
-
-
1942489264
-
Phosphoinositide deficiency due to inositol depletion is not a mechanism of lithium action in brain
-
Berry, G.T, Buccafusca, R., Greer, J.J., and Eccleston, E. Phosphoinositide deficiency due to inositol depletion is not a mechanism of lithium action in brain. Mol. Genet. Metab. 82, 87-92 (2004).
-
(2004)
Mol. Genet. Metab.
, vol.82
, pp. 87-92
-
-
Berry, G.T.1
Buccafusca, R.2
Greer, J.J.3
Eccleston, E.4
-
32
-
-
0015242494
-
Reduced brain inositol in lithium-treated rats
-
Allison, J.H. and Stewart, M.A. Reduced brain inositol in lithium-treated rats. Nat. New Biol. 233, 267-268 (1971).
-
(1971)
Nat. New Biol.
, vol.233
, pp. 267-268
-
-
Allison, J.H.1
Stewart, M.A.2
-
33
-
-
0008836304
-
Lithium, phosphatidylinositol signaling, and bipolar disorder
-
Belmaker, R.H. (ed.) Washington, DC: American Psychiatric Press, Inc
-
Atack, J.R. Lithium, phosphatidylinositol signaling, and bipolar disorder. In: Bipolar medications: Mechanism of action. Belmaker, R.H. (ed.) Washington, DC: American Psychiatric Press, Inc. (2000).
-
(2000)
Bipolar Medications: Mechanism of Action
-
-
Atack, J.R.1
-
34
-
-
0032744013
-
Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness
-
Moore, G.J., Bebchuk, J.M., Parrish, J.K., Faulk, M.W., Arfken, C.L., Strahl-Bevacqua, J., and Manji, H.K. Temporal dissociation between lithium-induced changes in frontal lobe myo-inositol and clinical response in manic-depressive illness. Am. J. Psychiatry 156, 1902-1908 (1999).
-
(1999)
Am. J. Psychiatry
, vol.156
, pp. 1902-1908
-
-
Moore, G.J.1
Bebchuk, J.M.2
Parrish, J.K.3
Faulk, M.W.4
Arfken, C.L.5
Strahl-Bevacqua, J.6
Manji, H.K.7
-
35
-
-
0030898340
-
Inositol monophosphatase inhibitors - Lithium mimetics?
-
Atack, J.R. Inositol monophosphatase inhibitors - lithium mimetics? Med. Res. Rev. 17, 215-24 (1997).
-
(1997)
Med. Res. Rev.
, vol.17
, pp. 215-224
-
-
Atack, J.R.1
-
36
-
-
0027458537
-
In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330
-
Atack, J.R., Cook, S.M., Watt, A.P., Fletcher, S.R., and Ragan, C.I. In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330. J. Neurochem. 60, 652-658 (1993).
-
(1993)
J. Neurochem.
, vol.60
, pp. 652-658
-
-
Atack, J.R.1
Cook, S.M.2
Watt, A.P.3
Fletcher, S.R.4
Ragan, C.I.5
-
37
-
-
0028339390
-
Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers
-
Atack, J.R., Prior, A.M., Fletcher, S.R., Quirk, K., McKernan, R., and Ragan, C.I. Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers. J. Pharmacol. Exp. Ther. 270 70-76 (1994).
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 70-76
-
-
Atack, J.R.1
Prior, A.M.2
Fletcher, S.R.3
Quirk, K.4
McKernan, R.5
Ragan, C.I.6
-
38
-
-
0028234802
-
Mechanism of inositol monophosphatase, the putative target of lithium therapy
-
Pollack, S.J., Atack, J.R., Knowles, M.R., McAllister, G., Ragan, C.I., Baker, R., Fletcher, S.R, Iversen, L.L., and Broughton, H.B. Mechanism of inositol monophosphatase, the putative target of lithium therapy. Proc. Natl. Acad. Sci. U.S.A. 91, 5766-5770 (1994 ).
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 5766-5770
-
-
Pollack, S.J.1
Atack, J.R.2
Knowles, M.R.3
McAllister, G.4
Ragan, C.I.5
Baker, R.6
Fletcher, S.R.7
Iversen, L.L.8
Broughton, H.B.9
-
39
-
-
0026493674
-
Structure of inositol monophosphatase, the putative target of lithium therapy
-
Bone, R., Springer, J.P., and Atack, J.R. Structure of inositol monophosphatase, the putative target of lithium therapy. Proc. Natl. Acad. Sci. U.S.A. 89, 10031-10035 (1992).
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 10031-10035
-
-
Bone, R.1
Springer, J.P.2
Atack, J.R.3
-
40
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame, S. and Cohen, P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359, 1-16 (2001).
-
(2001)
Biochem. J.
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
41
-
-
0035909112
-
Judging a protein by more than its name: Gsk-3
-
Woodgett, J.R. Judging a protein by more than its name: Gsk-3. Sci. STKE RE12 (2001).
-
(2001)
Sci. STKE RE12
-
-
Woodgett, J.R.1
-
42
-
-
0036788036
-
The wnt signaling pathway in bipolar disorder
-
Gould, T.D. and Manji, H.K. The wnt signaling pathway in bipolar disorder. Neuroscientist 8, 497-511 (2002).
-
(2002)
Neuroscientist
, vol.8
, pp. 497-511
-
-
Gould, T.D.1
Manji, H.K.2
-
43
-
-
0037042065
-
Endophenotypes in bipolar disorder
-
[Erratum in: Am. J. Med. Genet. 114, 592 (2002).]
-
Lenox, R.H., Gould, T.D., and Manji, H.K. Endophenotypes in bipolar disorder. Am. J. Med. Genet. 114, 391-406 (2002). [Erratum in: Am. J. Med. Genet. 114, 592 (2002).]
-
(2002)
Am. J. Med. Genet.
, vol.114
, pp. 391-406
-
-
Lenox, R.H.1
Gould, T.D.2
Manji, H.K.3
-
44
-
-
0036214603
-
Mood stabilizers, glycogen synthase kinase-3beta and cell survival
-
Jope, R.S. and Bijur, G.N. Mood stabilizers, glycogen synthase kinase-3beta and cell survival. Mol. Psychiatry 7 Suppl. 1, S35-S45 (2002).
-
(2002)
Mol. Psychiatry
, vol.7
, Issue.SUPPL. 1
-
-
Jope, R.S.1
Bijur, G.N.2
-
45
-
-
0032827466
-
Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked?
-
Manji, H.K., Moore, G.J., and Chen, G. Lithium at 50: Have the neuroprotective effects of this unique cation been overlooked? Biol Psychiatry 46, 929-40 (1999).
-
(1999)
Biol Psychiatry
, vol.46
, pp. 929-940
-
-
Manji, H.K.1
Moore, G.J.2
Chen, G.3
-
46
-
-
4243165658
-
Emerging experimental therapeutics for bipolar disorder: Clues from the molecular pathophysiology
-
Quiroz, J.A., Singh, J., Gould, TD., Denicoff, K.D., Zarate, C.A., and Manji, H.K. Emerging experimental therapeutics for bipolar disorder: Clues from the molecular pathophysiology. Mol Psychiatry 9, 756-776 (2004).
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 756-776
-
-
Quiroz, J.A.1
Singh, J.2
Gould, T.D.3
Denicoff, K.D.4
Zarate, C.A.5
Manji, H.K.6
-
47
-
-
0036116367
-
Neuroprotective effects of lithium in cultured cells and animal models of diseases
-
Chuang, D.M., Chen, R., Chalecka-Franaszek, E. et al. Neuroprotective effects of lithium in cultured cells and animal models of diseases. Bipolar Disord. 4, 129-136 (2002).
-
(2002)
Bipolar. Disord.
, vol.4
, pp. 129-136
-
-
Chuang, D.M.1
Chen, R.2
Chalecka-Franaszek, E.3
-
48
-
-
0022622039
-
Lithium-induced respecification of pattern in Xenopus laevis embryos
-
Kao, K.R., Masui, Y., and Elinson, R.P. Lithium-induced respecification of pattern in Xenopus laevis embryos. Nature 322 371-373 (1986).
-
(1986)
Nature
, vol.322
, pp. 371-373
-
-
Kao, K.R.1
Masui, Y.2
Elinson, R.P.3
-
49
-
-
0028931511
-
Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos
-
He, X., Saint-Jeannet, J.P., Woodgett, J.R., Varmus, H.E., and Dawid, I.B. Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos. Nature 375, 617-622 (1995).
-
(1995)
Nature
, vol.375
, pp. 617-622
-
-
He, X.1
Saint-Jeannet, J.P.2
Woodgett, J.R.3
Varmus, H.E.4
Dawid, I.B.5
-
50
-
-
0036810240
-
Lithium and valproic acid: Parallels and contrasts in diverse signaling contexts
-
Gurvich, N. and Klein, P.S. Lithium and valproic acid: Parallels and contrasts in diverse signaling contexts. Pharmacol. Ther. 96, 45-66 (2002).
-
(2002)
Pharmacol. Ther.
, vol.96
, pp. 45-66
-
-
Gurvich, N.1
Klein, P.S.2
-
51
-
-
0031567583
-
Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons
-
Munoz-Montano, J.R., Moreno, F.J., Avila, J., and Diaz-Nido, J. Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons. FEBS Lett. 411, 183-188 (1997).
-
(1997)
FEBS Lett.
, vol.411
, pp. 183-188
-
-
Munoz-Montano, J.R.1
Moreno, F.J.2
Avila, J.3
Diaz-Nido, J.4
-
52
-
-
0346688565
-
In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3
-
Gould, T.D., Chen, G., and Manji, H.K. In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology 29, 32-38 (2004).
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 32-38
-
-
Gould, T.D.1
Chen, G.2
Manji, H.K.3
-
53
-
-
3342955475
-
Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium
-
O'Brien, W.T., Harper, A.D., Jove, F, Woodgett, J.R., Maretto, S., Piccolo, S., and Klein, P.S. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J. Neurosci. 24, 6791-6798 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 6791-6798
-
-
O'Brien, W.T.1
Harper, A.D.2
Jove, F.3
Woodgett, J.R.4
Maretto, S.5
Piccolo, S.6
Klein, P.S.7
-
54
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
Phiel, C.J., Wilson, C.A., Lee, V.M., and Klein, P.S. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 423, 435-439 (2003).
-
(2003)
Nature
, vol.423
, pp. 435-439
-
-
Phiel, C.J.1
Wilson, C.A.2
Lee, V.M.3
Klein, P.S.4
-
55
-
-
0037087220
-
Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
-
Sun, X., Sato, S., Murayama, O., Murayama, M., Park, J.M., Yamaguchi, H., and Takashima, A. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 321, 61-64 (2002).
-
(2002)
Neurosci. Lett.
, vol.321
, pp. 61-64
-
-
Sun, X.1
Sato, S.2
Murayama, O.3
Murayama, M.4
Park, J.M.5
Yamaguchi, H.6
Takashima, A.7
-
56
-
-
2642552331
-
Lithium, a common drug for Bipolar Disorder treatment, regulates amyloid-β precursor protein processing
-
Su, Y., Ryder, J., Li, B. et al. Lithium, a common drug for Bipolar Disorder treatment, regulates amyloid-β precursor protein processing. Biochemistry 43, 6899-6908 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 6899-6908
-
-
Su, Y.1
Ryder, J.2
Li, B.3
-
57
-
-
1842420631
-
Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus
-
Kaidanovich-Beilin, O., Milman, A., Weizman, A., Pick, C.G., and Eldar-Finkelman, H. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus. Biol. Psychiatry 55, 781-784 (2004).
-
(2004)
Biol. Psychiatry
, vol.55
, pp. 781-784
-
-
Kaidanovich-Beilin, O.1
Milman, A.2
Weizman, A.3
Pick, C.G.4
Eldar-Finkelman, H.5
-
58
-
-
7244222408
-
AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
-
[Epub ahead of print] Jul
-
Gould, T.D., Einat, H., Bhat, R., and Manji, H.K. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int J. Neuropsychopharmacol. Jul 26, 1-4 (2004). [Epub ahead of print]
-
(2004)
Int J. Neuropsychopharmacol.
, vol.26
, pp. 1-4
-
-
Gould, T.D.1
Einat, H.2
Bhat, R.3
Manji, H.K.4
-
59
-
-
3242761438
-
In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain
-
Li, X., Zhu, W., Roh, M.S., Friedman, A.B., Rosborough, K., and Jope, R.S. In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain. Neuropsychopharmacology 29, 1426-1431 (2004).
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1426-1431
-
-
Li, X.1
Zhu, W.2
Roh, M.S.3
Friedman, A.B.4
Rosborough, K.5
Jope, R.S.6
-
60
-
-
1842787936
-
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
-
Beaulieu, J.M., Sotnikova, T.D., Yao, W.D., Kockeritz, L., Woodgett, J.R., Gainetdinov, R.R., and Caron, M.G. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc. Natl. Acad. Sci. U.S.A. 101, 5099-5104 (2004).
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 5099-5104
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Yao, W.D.3
Kockeritz, L.4
Woodgett, J.R.5
Gainetdinov, R.R.6
Caron, M.G.7
-
61
-
-
0036398986
-
The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes
-
Kaidanovich, O. and Eldar-Finkelman, H. The role of glycogen synthase kinase-3 in insulin resistance and Type 2 diabetes. Expert Opin. Ther. Targets 6, 555-561 (2002).
-
(2002)
Expert Opin. Ther. Targets
, vol.6
, pp. 555-561
-
-
Kaidanovich, O.1
Eldar-Finkelman, H.2
-
62
-
-
0036769733
-
GSK3beta signalling: Casting a wide net in Alzheimer's disease
-
Bhat, R.V. and Budd, S.L. GSK3beta signalling: Casting a wide net in Alzheimer's disease. Neurosignals 11, 251-261 (2002 ).
-
(2002)
Neurosignals
, vol.11
, pp. 251-261
-
-
Bhat, R.V.1
Budd, S.L.2
-
63
-
-
0036276050
-
Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
-
Alvarez, G., Munoz-Montano, J.R., Satrustegui, J., Avila, J., Bogonez, E., and Diaz-Nido, J. Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord. 4 153-165 (2002).
-
(2002)
Bipolar. Disord.
, vol.4
, pp. 153-165
-
-
Alvarez, G.1
Munoz-Montano, J.R.2
Satrustegui, J.3
Avila, J.4
Bogonez, E.5
Diaz-Nido, J.6
-
64
-
-
2642552331
-
Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing
-
Su, Y., Ryder, J., Li, B. et al. Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing. Biochemistry 43, 6899-6908 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 6899-6908
-
-
Su, Y.1
Ryder, J.2
Li, B.3
-
65
-
-
0037040856
-
Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase - Dependent pathway is cardioprotective
-
Tong, H., Imahashi, K., Steenbergen, C., and Murphy, E. Phosphorylation of glycogen synthase kinase-3beta during preconditioning through a phosphatidylinositol-3-kinase - dependent pathway is cardioprotective. Circ. Res. 8, 377-379 (2002).
-
(2002)
Circ. Res.
, vol.8
, pp. 377-379
-
-
Tong, H.1
Imahashi, K.2
Steenbergen, C.3
Murphy, E.4
-
66
-
-
0035477020
-
GSK3 takes centre stage more than 20 years after its discovery
-
Frame, S., and Cohen, P. GSK3 takes centre stage more than 20 years after its discovery. Biochem. J. 359, 1-16 (2001).
-
(2001)
Biochem. J.
, vol.359
, pp. 1-16
-
-
Frame, S.1
Cohen, P.2
-
67
-
-
0037609376
-
Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model
-
Ren, M., Senatorov, V.V., Chen, R.W, and Chuang, D.M. Postinsult treatment with lithium reduces brain damage and facilitates neurological recovery in a rat ischemia/reperfusion model. Proc. Natl. Acad. Sci. U.S.A. 100, 6210-6215 (2003).
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 6210-6215
-
-
Ren, M.1
Senatorov, V.V.2
Chen, R.W.3
Chuang, D.M.4
-
68
-
-
0034718421
-
Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration
-
Bhat, R.V., Shanley, J., Correll, M.R, Fieles, W.E., Keith, R.A., Scott, C.W., and Lee, C.M. Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration. Proc. Natl. Acad. Sci. U.S.A. 97, 11074-11079 (2000).
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 11074-11079
-
-
Bhat, R.V.1
Shanley, J.2
Correll, M.R.3
Fieles, W.E.4
Keith, R.A.5
Scott, C.W.6
Lee, C.M.7
-
69
-
-
0018972024
-
Purification and properties of liver fructose 1,6-bisphosphatase from C57BL/KsJ normal and diabetic mice
-
Marcus, F. and Hosey, M.M. Purification and properties of liver fructose 1,6-bisphosphatase from C57BL/KsJ normal and diabetic mice. J. Biol. Chem. 255, 2481-2486 (1980).
-
(1980)
J. Biol. Chem.
, vol.255
, pp. 2481-2486
-
-
Marcus, F.1
Hosey, M.M.2
-
70
-
-
0017179353
-
Size-dependent allosteric effects of monovalent cations on rabbit liver fructose- 1,6-bisphosphatase
-
Nakashima, K. and Tuboi, S. Size-dependent allosteric effects of monovalent cations on rabbit liver fructose- 1,6-bisphosphatase. J. Biol. Chem. 251, 4315-4321 (1976).
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 4315-4321
-
-
Nakashima, K.1
Tuboi, S.2
-
71
-
-
0029088924
-
Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase
-
Villeret, V., Huang, S., Fromm, H.J., and Lipscomb, W.N. Crystallographic evidence for the action of potassium, thallium, and lithium ions on fructose-1,6-bisphosphatase. Proc. Natl. Acad. Sci. U.S.A. 92, 8916-8920 (1995).
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 8916-8920
-
-
Villeret, V.1
Huang, S.2
Fromm, H.J.3
Lipscomb, W.N.4
-
72
-
-
0029980322
-
Kinetics and mechanisms of activation and inhibition of porcine liver fructose-1,6-bisphosphatase by monovalent cations
-
Zhang, R., Villeret, V., Lipscomb, W.N., and Fromm, H. Kinetics and mechanisms of activation and inhibition of porcine liver fructose-1,6-bisphosphatase by monovalent cations. Biochemistry 35, 3038-3043 (1996).
-
(1996)
Biochemistry
, vol.35
, pp. 3038-3043
-
-
Zhang, R.1
Villeret, V.2
Lipscomb, W.N.3
Fromm, H.4
-
73
-
-
0038778445
-
3-(2-carboxyethyl)-4,6-dichloro-1 H-indole-2-carboxylic acid: An allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site
-
Wright, S.W., Carlo, A.A., Danley, D.E. et al. 3-(2-carboxyethyl)-4,6-dichloro-1 H-indole-2-carboxylic acid: An allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site. Bioorg. Med. Chem. Lett. 13, 2055-2058 (2003).
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 2055-2058
-
-
Wright, S.W.1
Carlo, A.A.2
Danley, D.E.3
-
74
-
-
0039772523
-
A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3′-phosphoadenosine 5′-phosphate phosphatase and inositol-polyphosphate 1-phosphatase
-
Lopez-Coronado, J.M., Belles, J.M., Lesage, F., Serrano, R., and Rodriguez. P.L. A novel mammalian lithium-sensitive enzyme with a dual enzymatic activity, 3′-phosphoadenosine 5′-phosphate phosphatase and inositol-polyphosphate 1-phosphatase. J. Biol. Chem. 274, 16034-16039 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 16034-16039
-
-
Lopez-Coronado, J.M.1
Belles, J.M.2
Lesage, F.3
Serrano, R.4
Rodriguez, P.L.5
-
75
-
-
0033967752
-
A novel target of lithium therapy
-
Yenush, L., Belles, J.M., Lopez-Coronado, J.M., Gil-Mascarell, R., Serrano, R., and Rodriguez, P.L. A novel target of lithium therapy. FEBS Lett. 467, 321-325 (2000).
-
(2000)
FEBS Lett.
, vol.467
, pp. 321-325
-
-
Yenush, L.1
Belles, J.M.2
Lopez-Coronado, J.M.3
Gil-Mascarell, R.4
Serrano, R.5
Rodriguez, P.L.6
-
76
-
-
0036305698
-
Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3′-phosphoadenosine-5′-phosphate phosphatase activities: A novel target of lithium therapy
-
Patel, S., Yenush, L., Rodriguez, P.L., Serrano, R., and Blundell, T.L. Crystal structure of an enzyme displaying both inositol-polyphosphate-1-phosphatase and 3′-phosphoadenosine-5′-phosphate phosphatase activities: A novel target of lithium therapy. J. Mol. Biol. 315, 677-685 (2002).
-
(2002)
J. Mol. Biol.
, vol.315
, pp. 677-685
-
-
Patel, S.1
Yenush, L.2
Rodriguez, P.L.3
Serrano, R.4
Blundell, T.L.5
-
77
-
-
0041630998
-
Possible role of 3′(2′)-phosphoadenosine-5′-phosphate phosphatase in the etiology and therapy of bipolar disorder
-
Agam, G. and Shaltiel, G. Possible role of 3′(2′)-phosphoadenosine-5′-phosphate phosphatase in the etiology and therapy of bipolar disorder. Prog. Neuropsychopharm. Biol. Psych. 27, 723-727 (2003).
-
(2003)
Prog. Neuropsychopharm. Biol. Psych.
, vol.27
, pp. 723-727
-
-
Agam, G.1
Shaltiel, G.2
-
78
-
-
0036214671
-
Synaptic plasticity and mood disorders
-
Duman, R.S. Synaptic plasticity and mood disorders. Mol. Psychiatry 7 Suppl. 1, S29-S34 (2002).
-
(2002)
Mol. Psychiatry
, vol.7
, Issue.SUPPL. 1
-
-
Duman, R.S.1
-
79
-
-
0035295487
-
Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics. Psychopharmacol
-
Manji, H.K. and Duman, R.S. Impairments of neuroplasticity and cellular resilience in severe mood disorders: Implications for the development of novel therapeutics. Psychopharmacol. Bull. 35, 5-49 (2001).
-
(2001)
Bull.
, vol.35
, pp. 5-49
-
-
Manji, H.K.1
Duman, R.S.2
-
80
-
-
0043240266
-
The role of the extracellular signal-regulated kinase signaling pathway in mood modulation
-
Einat, H., Yuan, P., Gould, T.D., Li, J., Du, J., Zhang, L., Manji, H.K., and Chen, G. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. J. Neurosci. 23, 7311-7316 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 7311-7316
-
-
Einat, H.1
Yuan, P.2
Gould, T.D.3
Li, J.4
Du, J.5
Zhang, L.6
Manji, H.K.7
Chen, G.8
-
81
-
-
0034795827
-
Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain
-
Fukumoto, T, Morinobu, S., Okamoto, Y., Kagaya, A., and Yamawaki, S. Chronic lithium treatment increases the expression of brain-derived neurotrophic factor in the rat brain. Psychopharmacology (Berl.) 158, 100-106 (2001).
-
(2001)
Psychopharmacology (Berl.)
, vol.158
, pp. 100-106
-
-
Fukumoto, T.1
Morinobu, S.2
Okamoto, Y.3
Kagaya, A.4
Yamawaki, S.5
-
82
-
-
0141927282
-
Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line - Derived neurotrophic factor in a rat model of depression
-
Angelucci, F., Aloe, L., Jimenez-Vasquez, P., and Mathe, A.A. Lithium treatment alters brain concentrations of nerve growth factor, brain-derived neurotrophic factor and glial cell line - derived neurotrophic factor in a rat model of depression. Int. J. Neuropsychopharmacol. 6, 225-231 (2003).
-
(2003)
Int. J. Neuropsychopharmacol.
, vol.6
, pp. 225-231
-
-
Angelucci, F.1
Aloe, L.2
Jimenez-Vasquez, P.3
Mathe, A.A.4
-
83
-
-
0033013011
-
A bimodal model of the mechanism of action of lithium
-
Jope, R.S. A bimodal model of the mechanism of action of lithium. Mol. Psychiatry 4, 21-25 (1999).
-
(1999)
Mol. Psychiatry
, vol.4
, pp. 21-25
-
-
Jope, R.S.1
-
84
-
-
0031973757
-
Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin
-
Kofman, O., Li, P.P., and Warsh, J.J. Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin. Pharmacol. Biochem. Behav. 59, 191-200 (1998).
-
(1998)
Pharmacol. Biochem. Behav.
, vol.59
, pp. 191-200
-
-
Kofman, O.1
Li, P.P.2
Warsh, J.J.3
-
85
-
-
0018597959
-
Changes in lymphocyte beta-adrenergic receptors in depression and mania
-
Extein, I., Tallman, J., Smith, C.C., and Goodwin, F.K. Changes in lymphocyte beta-adrenergic receptors in depression and mania. Psychiatry Res. 191-197 (1979).
-
(1979)
Psychiatry Res.
, pp. 191-197
-
-
Extein, I.1
Tallman, J.2
Smith, C.C.3
Goodwin, F.K.4
-
86
-
-
0022997635
-
The cyclic AMP second messenger system in man: The effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification
-
Ebstein, R.P., Oppenheim, G., Ebstein, B.S., Amiri, Z., and Stessman, J. The cyclic AMP second messenger system in man: The effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification. Prog. Neuropsychopharmacol. Biol. Psychiatry 10 323-353 (1986).
-
(1986)
Prog. Neuropsychopharmacol. Biol. Psychiatry
, vol.10
, pp. 323-353
-
-
Ebstein, R.P.1
Oppenheim, G.2
Ebstein, B.S.3
Amiri, Z.4
Stessman, J.5
-
87
-
-
0002469960
-
Signal transduction abnormalities in bipolar disorder
-
Joffe, R.T. (ad.) New York: Dekker
-
Wang. J.-F, Young, L.T, Li, P.P., and Warsh, J.J. Signal transduction abnormalities in bipolar disorder. In: Bipolar disorder: Biological Models and Their Clinical Application. Joffe, R.T. (ad.) New York: Dekker, 41-79 (1997).
-
(1997)
Bipolar Disorder: Biological Models and Their Clinical Application
, pp. 41-79
-
-
Wang, J.-F.1
Young, L.T.2
Li, P.P.3
Warsh, J.J.4
-
88
-
-
0033136873
-
The interactions of adenylate cyclases with P-site inhibitors
-
Dessauer, C.W., Tesmer, J.J., Sprang, S.R., and Gilman, A.G. The interactions of adenylate cyclases with P-site inhibitors. Trends Pharmacol. Sci. 20, 205-210 (1999).
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 205-210
-
-
Dessauer, C.W.1
Tesmer, J.J.2
Sprang, S.R.3
Gilman, A.G.4
-
89
-
-
0038717215
-
Isoform-specific regulation of adenylyl cyclase: A potential target in future pharmacotherapy
-
Iwatsubo, K., Tsunematsu, T., and Ishikawa, Y. Isoform-specific regulation of adenylyl cyclase: A potential target in future pharmacotherapy. Expert Opin. Ther. Targets 7, 441-451 (2003).
-
(2003)
Expert Opin. Ther. Targets
, vol.7
, pp. 441-451
-
-
Iwatsubo, K.1
Tsunematsu, T.2
Ishikawa, Y.3
-
90
-
-
0034043203
-
CaM-kinases: Modulators of synaptic plasticity
-
Soderling, T.R. CaM-kinases: Modulators of synaptic plasticity. Curr. Opin. Neurobiol. 10, 375-380 (2000).
-
(2000)
Curr. Opin. Neurobiol.
, vol.10
, pp. 375-380
-
-
Soderling, T.R.1
-
91
-
-
0033570745
-
Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: Molecular transduction of mood stabilization in the treatment of manic-depressive illness
-
Manji, H.K. and Lenox, R.H. Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: Molecular transduction of mood stabilization in the treatment of manic-depressive illness. Biol. Psychiatry 46, 1328-1351 (1999).
-
(1999)
Biol. Psychiatry
, vol.46
, pp. 1328-1351
-
-
Manji, H.K.1
Lenox, R.H.2
-
92
-
-
0034209028
-
The high affinity inositol transport system - Implications for the pathophysiology and treatment of bipolar disorder
-
van Calker, D. and Belmaker, R.H. The high affinity inositol transport system - implications for the pathophysiology and treatment of bipolar disorder. Bipolar Disord. 2, 102-107 (2000).
-
(2000)
Bipolar. Disord.
, vol.2
, pp. 102-107
-
-
van Calker, D.1
Belmaker, R.H.2
-
93
-
-
0032864255
-
Inhibition of the high affinity myo-inositol transport system: A common mechanism of action of antibipolar drugs?
-
Lubrich, B. and van Calker, D. Inhibition of the high affinity myo-inositol transport system: A common mechanism of action of antibipolar drugs? Neuropsychopharmacology 21, 519-529 (1999).
-
(1999)
Neuropsychopharmacology
, vol.21
, pp. 519-529
-
-
Lubrich, B.1
van Calker, D.2
-
94
-
-
0037118050
-
A common mechanism of action for three mood-stabilizing drugs
-
Williams, R.S., Cheng, L., Mudge, A.W., and Harwood, A.J. A common mechanism of action for three mood-stabilizing drugs. Nature 417, 292-295 (2002).
-
(2002)
Nature
, vol.417
, pp. 292-295
-
-
Williams, R.S.1
Cheng, L.2
Mudge, A.W.3
Harwood, A.J.4
-
95
-
-
0026451081
-
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
-
Nishizuka, Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 258, 607-614 (1992).
-
(1992)
Science
, vol.258
, pp. 607-614
-
-
Nishizuka, Y.1
-
96
-
-
0030272375
-
Modulation of protein kinase C isozymes and substrates by lithium: The role of myo-inositol
-
Manji, H.K., Bersudsky, Y., Chen, G., Belmaker, R.H., and Potter, W.Z. Modulation of protein kinase C isozymes and substrates by lithium: The role of myo-inositol. Neuropsychopharmacology 15 370-381 (1996).
-
(1996)
Neuropsychopharmacology
, vol.15
, pp. 370-381
-
-
Manji, H.K.1
Bersudsky, Y.2
Chen, G.3
Belmaker, R.H.4
Potter, W.Z.5
-
97
-
-
0027366278
-
Lithium decreases membrane-associated protein kinase C in hippocampus: Selectivity for the alpha isozyme
-
Manji, H.K., Etcheberrigaray, R., Chen, G., and Olds, J.L. Lithium decreases membrane-associated protein kinase C in hippocampus: Selectivity for the alpha isozyme. J. Neurochem. 61, 2303-2310 (1993).
-
(1993)
J. Neurochem.
, vol.61
, pp. 2303-2310
-
-
Manji, H.K.1
Etcheberrigaray, R.2
Chen, G.3
Olds, J.L.4
-
98
-
-
0028850086
-
Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells
-
Li, X. and Jope, R.S. Selective inhibition of the expression of signal transduction proteins by lithium in nerve growth factor-differentiated PC12 cells. J. Neurochem. 65, 2500-2508 (1995).
-
(1995)
J. Neurochem.
, vol.65
, pp. 2500-2508
-
-
Li, X.1
Jope, R.S.2
-
99
-
-
0026567408
-
Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
-
Lenox, R.H., Watson, D.G., Patel, J., and Ellis, J. Chronic lithium administration alters a prominent PKC substrate in rat hippocampus. Brain Res. 570, 333-340 (1992).
-
(1992)
Brain Res.
, vol.570
, pp. 333-340
-
-
Lenox, R.H.1
Watson, D.G.2
Patel, J.3
Ellis, J.4
-
100
-
-
0030036555
-
Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: Potentiation by muscarinic receptor activation
-
Watson, D.G., and Lenox, R.H. Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: Potentiation by muscarinic receptor activation. J. Neurochem. 67, 767-777 (1996).
-
(1996)
J. Neurochem.
, vol.67
, pp. 767-777
-
-
Watson, D.G.1
Lenox, R.H.2
-
101
-
-
0026533049
-
Sensitization, kindling, and carbamazepine: An update on their implications for the course of affective illness
-
Post, R.M., Susan, R., and Weiss, B. Sensitization, kindling, and carbamazepine: An update on their implications for the course of affective illness, in Pharmacopsychiatry 25, 41-43 (1992).
-
(1992)
Pharmacopsychiatry
, vol.25
, pp. 41-43
-
-
Post, R.M.1
Susan, R.2
Weiss, B.3
-
102
-
-
0345554745
-
New approaches to modeling bipolar disorder
-
Einat, H., Manji H.K., and Belmaker, R.H. New approaches to modeling bipolar disorder. Psychopharm. Bull. 37, 47-63 (2003).
-
(2003)
Psychopharm. Bull.
, vol.37
, pp. 47-63
-
-
Einat, H.1
Manji, H.K.2
Belmaker, R.H.3
-
103
-
-
0025776394
-
Long-lasting enhancement of the membrane-associated protein kinase C activity in the hippocampal-kindled rat
-
Daigen, A., Akiyama, K., Itoh, T, Kohira, I., Sora, I., Morimoto, K., and Otsuki, S. Long-lasting enhancement of the membrane-associated protein kinase C activity in the hippocampal-kindled rat. Jpn. J. Psychiatry Neurol. 45, 297-301 (1991).
-
(1991)
Jpn. J. Psychiatry Neurol.
, vol.45
, pp. 297-301
-
-
Daigen, A.1
Akiyama, K.2
Itoh, T.3
Kohira, I.4
Sora, I.5
Morimoto, K.6
Otsuki, S.7
-
104
-
-
0026787868
-
Permanent increase in membrane-associated protein kinase C activity in the hippocampal-kindled rat
-
Kohira, I., Akiyama, K., Daigen, A., Itoh, T., Ono, M., Morimoto, K., Sora, I., and Otsuki, S. Permanent increase in membrane-associated protein kinase C activity in the hippocampal-kindled rat. Jpn. J. Psychiatry Neurol. 46, 510-512 (1992).
-
(1992)
Jpn. J. Psychiatry Neurol.
, vol.46
, pp. 510-512
-
-
Kohira, I.1
Akiyama, K.2
Daigen, A.3
Itoh, T.4
Ono, M.5
Morimoto, K.6
Sora, I.7
Otsuki, S.8
-
105
-
-
0028101999
-
Kindled amygdaloid seizures in rats cause immediate and transient increase in protein kinase C activity followed by transient suppression of the activity
-
Osonoe, K., Ogata, S., Iwata, Y., and Mori, N. Kindled amygdaloid seizures in rats cause immediate and transient increase in protein kinase C activity followed by transient suppression of the activity. Epilepsia 35, 850-854 (1994).
-
(1994)
Epilepsia
, vol.35
, pp. 850-854
-
-
Osonoe, K.1
Ogata, S.2
Iwata, Y.3
Mori, N.4
-
106
-
-
0028068110
-
Differential changes in the activities of multiple protein kinase C subspecies in the hippocampal-kindled rat
-
Ono, M., Akiyama, K., Tsutsui, K., and Kuroda, S. Differential changes in the activities of multiple protein kinase C subspecies in the hippocampal-kindled rat. Brain Res. 660, 27-33 (1994).
-
(1994)
Brain Res.
, vol.660
, pp. 27-33
-
-
Ono, M.1
Akiyama, K.2
Tsutsui, K.3
Kuroda, S.4
-
107
-
-
0029019938
-
Long-lasting increase in protein kinase C activity in the hippocampus of amygdala-kindled rat
-
Akiyama, K., Ono, M., Kohira, I., Daigen, A., Ishihara, T., and Kuroda, S. Long-lasting increase in protein kinase C activity in the hippocampus of amygdala-kindled rat. Brain Res. 679, 212-220 (1995).
-
(1995)
Brain Res.
, vol.679
, pp. 212-220
-
-
Akiyama, K.1
Ono, M.2
Kohira, I.3
Daigen, A.4
Ishihara, T.5
Kuroda, S.6
-
108
-
-
0028846262
-
Isozyme-specific changes in the expression of protein kinase C isozyme (alpha-zeta) genes in the hippocampus of rats induced by kindling epileptogenesis
-
Kamphuis, W., Hendriksen, E., and Lopes da Silva, F.H. Isozyme-specific changes in the expression of protein kinase C isozyme (alpha-zeta) genes in the hippocampus of rats induced by kindling epileptogenesis. Brain Res. 702, 94-100 (1995).
-
(1995)
Brain Res.
, vol.702
, pp. 94-100
-
-
Kamphuis, W.1
Hendriksen, E.2
Lopes da Silva, F.H.3
-
109
-
-
0026940934
-
Amygdala kindling-induced seizures selectively impair spatial memory. 1. Behavioral characteristics and effects on hippocampal neuronal protein kinase C isoforms
-
Beldhuis, H.J., Everts, H.G, Van der Zee, E.A., Luiten, P.G., and Bohus, B. Amygdala kindling-induced seizures selectively impair spatial memory. 1. Behavioral characteristics and effects on hippocampal neuronal protein kinase C isoforms. Hippocampus 2, 397-409 (1992).
-
(1992)
Hippocampus
, vol.2
, pp. 397-409
-
-
Beldhuis, H.J.1
Everts, H.G.2
Van der Zee, E.A.3
Luiten, P.G.4
Bohus, B.5
-
110
-
-
0026770277
-
Amygdala kindling alters protein kinase C activity in dentate gyrus
-
Chen, S.J., Desai, M.A., Klann, E., Winder, D.G., Sweatt, J.D., and Conn, P.J. Amygdala kindling alters protein kinase C activity in dentate gyrus. J. Neurochem. 59, 1761-1769 (1992).
-
(1992)
J. Neurochem.
, vol.59
, pp. 1761-1769
-
-
Chen, S.J.1
Desai, M.A.2
Klann, E.3
Winder, D.G.4
Sweatt, J.D.5
Conn, P.J.6
-
111
-
-
0027015513
-
Kindling-induced changes of protein kinase C levels in hippocampus and neocortex
-
Buzsaki, G., Hsu, M., Horvath, Z., Horsburgh, K., Sundsmo, M., Masliah, E., and Saitoh, T. Kindling-induced changes of protein kinase C levels in hippocampus and neocortex. Epilepsy Res. Suppl. 9, 279-283 (1992).
-
(1992)
Epilepsy Res. Suppl.
, vol.9
, pp. 279-283
-
-
Buzsaki, G.1
Hsu, M.2
Horvath, Z.3
Horsburgh, K.4
Sundsmo, M.5
Masliah, E.6
Saitoh, T.7
-
112
-
-
0027221154
-
Long-term increase in protein kinase C-gamma and muscarinic acetylcholine receptor expression in the cerebral cortex of amygdala-kindled rats - A quantitative immunocytochemical study
-
Beldhuis, H.J., De Ruiter, A.J., Maes, F.W., Suzuki, T, and Bohus, B. Long-term increase in protein kinase C-gamma and muscarinic acetylcholine receptor expression in the cerebral cortex of amygdala-kindled rats - a quantitative immunocytochemical study. Neuroscience 55, 965-973 (1993).
-
(1993)
Neuroscience
, vol.55
, pp. 965-973
-
-
Beldhuis, H.J.1
De Ruiter, A.J.2
Maes, F.W.3
Suzuki, T.4
Bohus, B.5
-
113
-
-
0026621687
-
Protein kinase C and dopamine transport-2. Effects of amphetamine in vitro
-
Giambalvo, C.T. Protein kinase C and dopamine transport-2. Effects of amphetamine in vitro. Neuropharmacology 31, 1211-1222 (1992).
-
(1992)
Neuropharmacology
, vol.31
, pp. 1211-1222
-
-
Giambalvo, C.T.1
-
114
-
-
0026715630
-
Protein kinase C and dopamine transport-1. Effects of amphetamine in vivo
-
Giambalvo, C.T. Protein kinase C and dopamine transport-1. Effects of amphetamine in vivo. Neuropharmacology, 31, 1201-1210 (1992).
-
(1992)
Neuropharmacology
, vol.31
, pp. 1201-1210
-
-
Giambalvo, C.T.1
-
115
-
-
0027385573
-
Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine
-
Gnegy, M.E., Hong, P., and Ferrell, S.T. Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine. Brain Res. Mol. Brain Res. 20, 289-298 (1993).
-
(1993)
Brain Res. Mol. Brain Res.
, vol.20
, pp. 289-298
-
-
Gnegy, M.E.1
Hong, P.2
Ferrell, S.T.3
-
116
-
-
0031443572
-
Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine
-
Iwata, S.I., Hewlett, G.H., Ferrell, S.T., Kantor, L., and Gnegy, M.E. Enhanced dopamine release and phosphorylation of synapsin I and neuromodulin in striatal synaptosomes after repeated amphetamine. J. Pharmacol. Exp. Ther. 283, 1445-1452 (1997).
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.283
, pp. 1445-1452
-
-
Iwata, S.I.1
Hewlett, G.H.2
Ferrell, S.T.3
Kantor, L.4
Gnegy, M.E.5
-
117
-
-
0030910710
-
Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes
-
Iwata, S., Hewlett, G.H., and Gnegy, M.E. Amphetamine increases the phosphorylation of neuromodulin and synapsin I in rat striatal synaptosomes. Synapse 26, 281-291 (1997).
-
(1997)
Synapse
, vol.26
, pp. 281-291
-
-
Iwata, S.1
Hewlett, G.H.2
Gnegy, M.E.3
-
118
-
-
0031933722
-
Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices
-
Kantor, L. and Gnegy, M.E. Protein kinase C inhibitors block amphetamine-mediated dopamine release in rat striatal slices. J. Pharmacol. Exp. Ther. 284, 592-598 (1998).
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.284
, pp. 592-598
-
-
Kantor, L.1
Gnegy, M.E.2
-
119
-
-
0027761105
-
Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies
-
Steketee, J.D. Injection of the protein kinase inhibitor H7 into the A10 dopamine region blocks the acute responses to cocaine: Behavioral and in vivo microdialysis studies. Neuropharmacology 32, 1289-1297 (1993).
-
(1993)
Neuropharmacology
, vol.32
, pp. 1289-1297
-
-
Steketee, J.D.1
-
120
-
-
0028568329
-
Intra-A10 injection of H7 blocks the development of sensitization to cocaine
-
Steketee, J.D. Intra-A10 injection of H7 blocks the development of sensitization to cocaine. Neuroreport 6, 69-72 (1994).
-
(1994)
Neuroreport
, vol.6
, pp. 69-72
-
-
Steketee, J.D.1
-
121
-
-
0342445420
-
A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania
-
Bebchuk, J.M., Arfken, C.L., Dolan-Manji, S., Murphy, J., Hasanat, K., and Manji, H.K. A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania. Arch. Gen. Psychiatry 57, 95-97 (2000).
-
(2000)
Arch. Gen. Psychiatry
, vol.57
, pp. 95-97
-
-
Bebchuk, J.M.1
Arfken, C.L.2
Dolan-Manji, S.3
Murphy, J.4
Hasanat, K.5
Manji, H.K.6
-
122
-
-
4243187646
-
Neurotrophic signaling in mood disorders
-
Gutkind, J.S. (ed.) Hoboken, NJ: John Wiley & Sons, Inc
-
Du, J., Gould, T.D., and Manji, H.K. Neurotrophic signaling in mood disorders. In: Signal Transduction and Human Disease. Gutkind, J.S. (ed.) Hoboken, NJ: John Wiley & Sons, Inc., 411-446 (2003).
-
(2003)
Signal Transduction and Human Disease
, pp. 411-446
-
-
Du, J.1
Gould, T.D.2
Manji, H.K.3
-
123
-
-
0036460741
-
Selective chronic stress-induced in vivo ERK1/2 hyperphosphorylation in medial prefrontocortical dendrites: Implications for stress-related cortical pathology?
-
Trentani, A., Kuipers, S.D., Ter Horst, G.J., and Den Boer, J.A. Selective chronic stress-induced in vivo ERK1/2 hyperphosphorylation in medial prefrontocortical dendrites: Implications for stress-related cortical pathology? Eur. J. Neurosci. 15, 1681-1691 (2002).
-
(2002)
Eur. J. Neurosci.
, vol.15
, pp. 1681-1691
-
-
Trentani, A.1
Kuipers, S.D.2
Ter Horst, G.J.3
Den Boer, J.A.4
-
124
-
-
0035949610
-
Social stress exacerbates stroke outcome by suppressing Bcl-2 expression
-
DeVries, A.C., Joh, H.D., Bernard, O., Hattori, K., Hurn, P.D., Traystman, R.J., and Alkayed, N.J. Social stress exacerbates stroke outcome by suppressing Bcl-2 expression. Proc. Natl. Acad. Sci. U.S.A. 98, 11824-11828 (2001).
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 11824-11828
-
-
DeVries, A.C.1
Joh, H.D.2
Bernard, O.3
Hattori, K.4
Hurn, P.D.5
Traystman, R.J.6
Alkayed, N.J.7
-
125
-
-
0035943699
-
The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth
-
Yuan, P.X., Huang, L.D., Jiang, Y.M., Gutkind, J.S., Manji, H.K., and Chen, G. The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth. J. Biol. Chem. 276, 31674-31683 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 31674-31683
-
-
Yuan, P.X.1
Huang, L.D.2
Jiang, Y.M.3
Gutkind, J.S.4
Manji, H.K.5
Chen, G.6
-
126
-
-
0032956630
-
The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
-
Chen, G., Zeng, W.Z., Yuan, P.X., Huang, L.D., Jiang, Y.M., Zhao, Z.H., and Manji, H.K. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J. Neurochem. 72, 879-882 (1999).
-
(1999)
J. Neurochem.
, vol.72
, pp. 879-882
-
-
Chen, G.1
Zeng, W.Z.2
Yuan, P.X.3
Huang, L.D.4
Jiang, Y.M.5
Zhao, Z.H.6
Manji, H.K.7
-
127
-
-
0036220487
-
PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers
-
Manji, H.K. and Chen, G. PKC, MAP kinases and the bcl-2 family of proteins as long-term targets for mood stabilizers. Mol. Psychiatry 7 Suppl.1, S46-S56 (2002).
-
(2002)
Mol. Psychiatry
, vol.7
, Issue.SUPPL. 1
-
-
Manji, H.K.1
Chen, G.2
-
128
-
-
0035039841
-
Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: Long-term effects on cell survival and transcript stability
-
Chen, G., Huang, L.D., Zeng, W.Z., and Manji, H.K. Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: Long-term effects on cell survival and transcript stability. Int. J. Neuropsychopharmacol. 4, 47-64 (2001).
-
(2001)
Int. J. Neuropsychopharmacol.
, vol.4
, pp. 47-64
-
-
Chen, G.1
Huang, L.D.2
Zeng, W.Z.3
Manji, H.K.4
-
129
-
-
0034589368
-
Histopathology of the prefrontal cortex in major depression: What does it tell us about dysfunctional monoaminergic circuits?
-
Rajkowska, G. Histopathology of the prefrontal cortex in major depression: What does it tell us about dysfunctional monoaminergic circuits? Prog. Brain Res. 126, 397-412 (2000).
-
(2000)
Prog. Brain Res.
, vol.126
, pp. 397-412
-
-
Rajkowska, G.1
-
130
-
-
0037249456
-
Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism
-
Huang, X., Wu, D.Y., Chen, G., Manji, H., and Chen, D.F. Support of retinal ganglion cell survival and axon regeneration by lithium through a Bcl-2-dependent mechanism. Invest. Ophthalmol. Vis. Sci. 44, 347-354 (2003).
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 347-354
-
-
Huang, X.1
Wu, D.Y.2
Chen, G.3
Manji, H.4
Chen, D.F.5
-
131
-
-
0036914074
-
Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity
-
Hashimoto, R., Takei, N., Shimazu, K., Christ, L., Lu, B., and Chuang, D.M. Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: An essential step for neuroprotection against glutamate excitotoxicity. Neuropharmacology 43, 1173-1179 (2002).
-
(2002)
Neuropharmacology
, vol.43
, pp. 1173-1179
-
-
Hashimoto, R.1
Takei, N.2
Shimazu, K.3
Christ, L.4
Lu, B.5
Chuang, D.M.6
-
132
-
-
0030935403
-
Subgenual prefrontal cortex abnormalities in mood disorders
-
Drevets, W.C., Price, J.L., Simpson, J.R., Jr., Todd, R.D., Reich, T., Vannier, M., and Raichle, M.E. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 386, 824-827 (1997 ).
-
(1997)
Nature
, vol.386
, pp. 824-827
-
-
Drevets, W.C.1
Price, J.L.2
Simpson Jr., J.R.3
Todd, R.D.4
Reich, T.5
Vannier, M.6
Raichle, M.E.7
-
133
-
-
0036753235
-
Low glial numbers in the amygdala in major depressive disorder
-
Bowley, M.P., Drevets, W.C., Ongur, D., and Price, J.L. Low glial numbers in the amygdala in major depressive disorder. Biol. Psychiatry 52, 404-412 (2002).
-
(2002)
Biol. Psychiatry
, vol.52
, pp. 404-412
-
-
Bowley, M.P.1
Drevets, W.C.2
Ongur, D.3
Price, J.L.4
-
134
-
-
0028978925
-
N-acetylaspartate in neuropsychiatric disorders
-
Tsai, G. and Coyle, J.T. N-acetylaspartate in neuropsychiatric disorders. Prog. Neurobiol. 46, 531-540 (1995).
-
(1995)
Prog. Neurobiol.
, vol.46
, pp. 531-540
-
-
Tsai, G.1
Coyle, J.T.2
-
135
-
-
18744435263
-
Lithium increases N-acetyl-aspartate in the human brain: In vivo evidence in support of bcl-2's neurotrophic effects?
-
Moore, G.J., Bebchuk, J.M., Hasanat, K. et al. Lithium increases N-acetyl-aspartate in the human brain: in vivo evidence in support of bcl-2's neurotrophic effects? Biol. Psychiatry 48, 1-8 (2000).
-
(2000)
Biol. Psychiatry
, vol.48
, pp. 1-8
-
-
Moore, G.J.1
Bebchuk, J.M.2
Hasanat, K.3
-
136
-
-
0034619037
-
Lithium-induced increase in human brain grey matter
-
Moore, G.J., Bebchuk, J.M., Wilds, I.B., Chen, G., and Manji, H.K. Lithium-induced increase in human brain grey matter. Lancet 356, 1241-1242 (2000).
-
(2000)
Lancet
, vol.356
, pp. 1241-1242
-
-
Moore, G.J.1
Bebchuk, J.M.2
Wilds, I.B.3
Chen, G.4
Manji, H.K.5
-
137
-
-
0037199676
-
Increased gray matter volume in lithium-treated bipolar disorder patients
-
Sassi, R., Nicoletti, M., Brambilla, P., Mallinger, A., Frank, E., Kupfer, D., Keshavan, M., and Soares, J. Increased gray matter volume in lithium-treated bipolar disorder patients. Neurosci. Lett. 329, 243 (2002).
-
(2002)
Neurosci. Lett.
, vol.329
, pp. 243
-
-
Sassi, R.1
Nicoletti, M.2
Brambilla, P.3
Mallinger, A.4
Frank, E.5
Kupfer, D.6
Keshavan, M.7
Soares, J.8
-
138
-
-
0346034866
-
Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients
-
Silverstone, P.H., Wu, R.H., O'Donnell, T., Ulrich, M., Asghar, S.J., and Hanstock, C.C. Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients. Int. Clin. Psychopharmacol. 18, 73-79 (2003).
-
(2003)
Int. Clin. Psychopharmacol.
, vol.18
, pp. 73-79
-
-
Silverstone, P.H.1
Wu, R.H.2
O'Donnell, T.3
Ulrich, M.4
Asghar, S.J.5
Hanstock, C.C.6
-
139
-
-
0023828843
-
2 via GTP-binding proteins: Arachidonic acid and its metabolites as second messengers
-
2 via GTP-binding proteins: Arachidonic acid and its metabolites as second messengers. Trends Neurosci. 11, 117-123 (1988).
-
(1988)
Trends Neurosci.
, vol.11
, pp. 117-123
-
-
Axelrod, J.1
Burch, R.M.2
Jelsema, C.L.3
-
140
-
-
0034912915
-
In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling
-
Rapoport, S.I. In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling. J. Mol. Neurosci. 16, 243-261 (2001).
-
(2001)
J. Mol. Neurosci.
, vol.16
, pp. 243-261
-
-
Rapoport, S.I.1
-
141
-
-
0028985121
-
Phospholipase A2 and G proteins
-
Axelrod, J. Phospholipase A2 and G proteins. Trends Neurosci. 18, 64-65 (1995).
-
(1995)
Trends Neurosci.
, vol.18
, pp. 64-65
-
-
Axelrod, J.1
-
142
-
-
0035010364
-
Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: A possible common effect of mood stabilizers
-
Chang, M.C., Contreras, M.A., Rosenberger, T.A., Rintala, J.J., Bell, J.M., and Rapoport, S.I. Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: A possible common effect of mood stabilizers. J. Neurochem. 77, 796-803 (2001).
-
(2001)
J. Neurochem.
, vol.77
, pp. 796-803
-
-
Chang, M.C.1
Contreras, M.A.2
Rosenberger, T.A.3
Rintala, J.J.4
Bell, J.M.5
Rapoport, S.I.6
-
143
-
-
0030596052
-
Lithium decreases turnover of arachidonate in several brain phospholipids
-
Erratum in: Neurosci. Lett. 222, 141 (1997)
-
Chang, M.C., Grange, E., Rabin, O., Bell, J.M., Allen, D.D., and Rapoport, S.I. Lithium decreases turnover of arachidonate in several brain phospholipids. Neurosci. Lett. 220, 171-174 (1996). Erratum in: Neurosci. Lett. 222, 141 (1997).
-
(1996)
Neurosci. Lett.
, vol.220
, pp. 171-174
-
-
Chang, M.C.1
Grange, E.2
Rabin, O.3
Bell, J.M.4
Allen, D.D.5
Rapoport, S.I.6
-
144
-
-
0036301389
-
Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?
-
Rapoport, S.I. and Bosetti, F. Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder? Arch. Gen. Psychiatry 59, 592-596 (2002).
-
(2002)
Arch. Gen. Psychiatry
, vol.59
, pp. 592-596
-
-
Rapoport, S.I.1
Bosetti, F.2
-
146
-
-
0033576743
-
2 is a target for chronic lithium in rat brain
-
2 is a target for chronic lithium in rat brain. Neuroreport 10, 3887-3890 (1999).
-
(1999)
Neuroreport
, vol.10
, pp. 3887-3890
-
-
Rintala, J.1
Seemann, R.2
Chandrasekaran, K.3
Rosenberger, T.A.4
Chang, L.5
Contreras, M.A.6
Rapoport, S.I.7
Chang, M.C.8
-
147
-
-
0036385734
-
2 concentration in rat brain
-
2 concentration in rat brain. Mol. Psychiatry 7, 845-850 (2002).
-
(2002)
Mol. Psychiatry
, vol.7
, pp. 845-850
-
-
Bosetti, F.1
Rintala, J.2
Seemann, R.3
Rosenberger, T.A.4
Contreras, M.A.5
Rapoport, S.I.6
Chang, M.C.7
-
148
-
-
0038673579
-
Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain
-
Bosetti, F., Weerasinghe, G.R., Rosenberger, T.A., and Rapoport, S.I. Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain. J. Neurochem. 85, 690-696 (2003).
-
(2003)
J. Neurochem.
, vol.85
, pp. 690-696
-
-
Bosetti, F.1
Weerasinghe, G.R.2
Rosenberger, T.A.3
Rapoport, S.I.4
-
150
-
-
0037162698
-
Cyclooxygenase inhibitor modulation of dopamine-related behaviours
-
Ross, B.M., Brooks, R.J., Lee, M., Kalasinsky, K.S., Vorce, S.P., Seeman, M., Fletcher, P.J., and Turenne, S.D. Cyclooxygenase inhibitor modulation of dopamine-related behaviours. Eur. J. Pharmacol. 450, 141-151 (2002).
-
(2002)
Eur. J. Pharmacol.
, vol.450
, pp. 141-151
-
-
Ross, B.M.1
Brooks, R.J.2
Lee, M.3
Kalasinsky, K.S.4
Vorce, S.P.5
Seeman, M.6
Fletcher, P.J.7
Turenne, S.D.8
-
151
-
-
0037006014
-
Evidence for the involvement of cyclooxygenase activity in the development of cocaine sensitization
-
Reid, M.S., Ho, L.B., Hsu, K., Fox, L., Tolliver, B.K., Adams, J.U., Franco, A., and Berger, S.P. Evidence for the involvement of cyclooxygenase activity in the development of cocaine sensitization. Pharmacol. Biochem. Behav. 71, 37-54 (2002).
-
(2002)
Pharmacol. Biochem. Behav.
, vol.71
, pp. 37-54
-
-
Reid, M.S.1
Ho, L.B.2
Hsu, K.3
Fox, L.4
Tolliver, B.K.5
Adams, J.U.6
Franco, A.7
Berger, S.P.8
-
152
-
-
0141860116
-
Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain
-
Madrigal, J.L., Moro, M.A., Lizasoain, I., Lorenzo, P., Fernandez, A.P., Rodrigo, J., Bosca, L., and Leza, J.C. Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain. Neuropsychopharmacology 28, 1579-1588 (2003).
-
(2003)
Neuropsychopharmacology
, vol.28
, pp. 1579-1588
-
-
Madrigal, J.L.1
Moro, M.A.2
Lizasoain, I.3
Lorenzo, P.4
Fernandez, A.P.5
Rodrigo, J.6
Bosca, L.7
Leza, J.C.8
-
153
-
-
7244244784
-
March treatment trial grant
-
Stanley Medical Institute. www.stanleyresearch.org
-
Soares, J. and Bowden, C. March treatment trial grant. Stanley Medical Institute. www.stanleyresearch.org (2002).
-
(2002)
-
-
Soares, J.1
Bowden, C.2
-
154
-
-
4243196940
-
Emerging experimental therapeutics for bipolar disorder: Insights from the molecular and cellular actions of current mood stabilizers
-
Gould, T.D., Quiroz, J.A., Singh, J., Zarate, C.A., and Manji, H.K. Emerging experimental therapeutics for bipolar disorder: Insights from the molecular and cellular actions of current mood stabilizers. Mol. Psychiatry 9, 734-755 (2004).
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 734-755
-
-
Gould, T.D.1
Quiroz, J.A.2
Singh, J.3
Zarate, C.A.4
Manji, H.K.5
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