Association study of the glycogen synthase kinase-3β gene polymorphism with prophylactic lithium response in bipolar patients

World Journal of Biological Psychiatry

Volumn 7, Issue 3, 2006, Pages 158-161

  Szczepankiewicz, Aleksandra ^a   Rybakowski, Janusz ^a   Suwalska, Aleksandra ^a   Skibińska, Maria ^a   Leszczynska Rodziewicz, Anna ^a   Dmitrzak Weglarz, Monika ^a   Czerski, Piotr ^a   Hauser, Joanna ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Association; Bipolar disorder; Glycogen synthase kinase 3 gene; Lithium response

Indexed keywords

CYSTEINE; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM; THREONINE;

ADULT; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL PATIENT; SEX DIFFERENCE; TREATMENT OUTCOME;

ADULT; ALLELES; ANTIMANIC AGENTS; BIPOLAR DISORDER; FEMALE; GENE FREQUENCY; GENOTYPE; GLYCOGEN SYNTHASE KINASE 3; HOMOZYGOTE; HUMANS; LITHIUM CARBONATE; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECURRENCE; STATISTICS; STATISTICS AS TOPIC; TREATMENT OUTCOME;

EID: 33746532204     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.1080/15622970600554711     Document Type: Article

References (18)

1. Beasley, C. (2002) An investigation of the Wnt-signalling pathway in the prefrontal cortex in schizophrenia, bipolar disorder and major depressive disorder Schizophr Res, 58, pp. 63-67.
2. Benedetti, F. (2004a) A single nucleotide polymorphism in glycogen synthase kinase 3-beta promoter gene influences onset of illness in patients affected by bipolar disorder Neurosci Lett, 355, pp. 37-340.
3. Benedetti, F. (2004b) A glycogen synthase kinase 3-beta promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression Neurosci Lett, 368, pp. 123-126.
4. Benedetti, F. (2005) Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-beta-50 T/C SNP Neurosci Lett, 376, pp. 51-55.
5. Gould, TD. (2004a) In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3 Neuropsychopharmacology, 29, pp. 32-38.
6. Gould, TD. (2004b) Glycogen synthase kinase-3: A target for novel bipolar disorder treatments J Clin Psychiatry, 65, pp. 10-21.
7. Grof, P. (1994) Lithium response and genetics of affective disorders J Affect Disord, 32, pp. 85-95.
8. Iwahana, E. (2004) Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei Eur J Neurosci, 19, pp. 2281-2287.
9. Lau, KF. (1999) Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter Genomics, 60, pp. 121-128.
10. Lesort, M. (1999) Glycogen synthase kinase-3beta, beta-catenin, and tau in postmortem bipolar brain J Neural Transm, 106, pp. 1217-1222.
11. Li, X. (2002) Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection Bipolar Disord, 4, pp. 137-144.
12. MacQueen, GM. (2005) The phenotypes of bipolar disorder: Relevance for genetic investigations Mol Psychiatry, 10, pp. 811-826.
13. Manji, HK and Zarate, CA. (2002) Molecular and cellular mechanisms underlying mood stabilization in bipolar disorder: Implications for the development of improved therapeutics Mol Psychiatry, 7(Suppl 1), pp. S1-7.
14. Martinek, S and Inonog, S and Manoukian, AS and Young, M. (2001) A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock Cell, 105, pp. 769-779.
15. Miller, SA. (1988) A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res, 16, pp. 1215.
16. Padiath, QS. (2004) Glycogen synthase kinase 3beta as a likely target for the action of lithium on circadian clocks Chronobiol Int, 21, pp. 43-55.
17. Russ, C. (2001) Identification of sequence variants and analysis of the role of the glycogen synthase kinase 3 beta gene and promoter in late onset Alzheimer's disease Mol Psychiatry, 6, pp. 320-324.
18. Rybakowski, JK. (2005) Prophylactic lithium response and polymorphism of the brain-derived neurotrophic factor gene Pharmacopsychiatry, 38, pp. 166-170.