-
1
-
-
0036119338
-
Molecular, pharmacological and functional diversity of 5-HT receptors
-
Hoyer D, Hannon JP, Martin GR. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacol Biochem Behav 2002; 71: 533-54.
-
(2002)
Pharmacol Biochem Behav
, vol.71
, pp. 533-554
-
-
Hoyer, D.1
Hannon, J.P.2
Martin, G.R.3
-
2
-
-
0035120410
-
Atypical antipsychotics: New directions and new challenges in the treatment of schizophrenia
-
Kapur S, Remington G. Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia. Annu Rev Med 2001;52:503-17.
-
(2001)
Annu Rev Med
, vol.52
, pp. 503-517
-
-
Kapur, S.1
Remington, G.2
-
3
-
-
20044378114
-
Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis
-
Seeman P, Weinshenker D, Quirion R, et al. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proc Natl Acad Sci U S A 2005;102:3513-8.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3513-3518
-
-
Seeman, P.1
Weinshenker, D.2
Quirion, R.3
-
4
-
-
0017277759
-
The dopamine hypothesis of schizophrenia: Focus on the dopamine receptor
-
Snyder SH. The dopamine hypothesis of schizophrenia: focus on the dopamine receptor. Am J Psychiatry 1976;133:197-202.
-
(1976)
Am J Psychiatry
, vol.133
, pp. 197-202
-
-
Snyder, S.H.1
-
5
-
-
0037264650
-
Plasma membrane monoamine transporters: Structure, regulation and function
-
Torres GE, Gainetdinov RR, Caron MG. Plasma membrane monoamine transporters: structure, regulation and function. Nat Rev Neurosci 2003;4:13-25.
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 13-25
-
-
Torres, G.E.1
Gainetdinov, R.R.2
Caron, M.G.3
-
6
-
-
9044252959
-
Tyrosine hydroxylase. The initial step in norepinephrine biosynthesis
-
Nagatsu T, Levitt M, Udenfriend S. Tyrosine hydroxylase. The initial step in norepinephrine biosynthesis. J Biol Chem 1964;239:2910-7.
-
(1964)
J Biol Chem
, vol.239
, pp. 2910-2917
-
-
Nagatsu, T.1
Levitt, M.2
Udenfriend, S.3
-
7
-
-
3042722258
-
Tryptophan hydroxylase- 2 controls brain serotonin synthesis
-
Zhang X, Beaulieu JM, Sotnikova TD, et al. Tryptophan hydroxylase- 2 controls brain serotonin synthesis. Science 2004;305:217.
-
(2004)
Science
, vol.305
, pp. 217
-
-
Zhang, X.1
Beaulieu, J.M.2
Sotnikova, T.D.3
-
8
-
-
0037414862
-
Synthesis of serotonin by a second tryptophan hydroxylase isoform
-
Walther DJ, Peter JU, Bashammakh S, et al. Synthesis of serotonin by a second tryptophan hydroxylase isoform. Science 2003;299:76.
-
(2003)
Science
, vol.299
, pp. 76
-
-
Walther, D.J.1
Peter, J.U.2
Bashammakh, S.3
-
9
-
-
30744436805
-
Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2
-
Zhang X, Beaulieu JM, Gainetdinov RR, et al. Functional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2. Cell Mol Life Sci 2006;63:6-11.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 6-11
-
-
Zhang, X.1
Beaulieu, J.M.2
Gainetdinov, R.R.3
-
11
-
-
79952032110
-
The physiology, signaling, and pharmacology of dopamine receptors
-
Beaulieu JM, Gainetdinov RR. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol Rev 2011;63:182-217.
-
(2011)
Pharmacol Rev
, vol.63
, pp. 182-217
-
-
Beaulieu, J.M.1
Gainetdinov, R.R.2
-
12
-
-
4644271084
-
Magic shotguns versus magic bullets: Selectively non-selective drugs for mood disorders and schizophrenia
-
Roth BL, Sheffler DJ, Kroeze WK. Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia. Nat Rev Drug Discov 2004;3:353-9.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 353-359
-
-
Roth, B.L.1
Sheffler, D.J.2
Kroeze, W.K.3
-
13
-
-
34248151448
-
A dopamine D2 receptor gene-related polymorphism is associated with schizophrenia in a Spanish population isolate
-
Parsons MJ, Mata I, Beperet M, et al. A dopamine D2 receptor gene-related polymorphism is associated with schizophrenia in a Spanish population isolate. Psychiatr Genet 2007;17:159-63.
-
(2007)
Psychiatr Genet
, vol.17
, pp. 159-163
-
-
Parsons, M.J.1
Mata, I.2
Beperet, M.3
-
14
-
-
54149094913
-
Genetic research in schizophrenia: New tools and future perspectives
-
Bertram L. Genetic research in schizophrenia: new tools and future perspectives. Schizophr Bull 2008;34:806-12.
-
(2008)
Schizophr Bull
, vol.34
, pp. 806-812
-
-
Bertram, L.1
-
15
-
-
77953425943
-
The dopamine D4 receptor: Biochemical and signalling properties
-
Rondou P, Haegeman G, Van Craenenbroeck K. The dopamine D4 receptor: biochemical and signalling properties. Cell Mol Life Sci 2010;67:1971-86.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 1971-1986
-
-
Rondou, P.1
Haegeman, G.2
van Craenenbroeck, K.3
-
16
-
-
70350140352
-
The genetics of attention-deficit/ hyperactivity disorder
-
Coghill D, Banaschewski T. The genetics of attention-deficit/ hyperactivity disorder. Expert Rev Neurother 2009;9:1547-65.
-
(2009)
Expert Rev Neurother
, vol.9
, pp. 1547-1565
-
-
Coghill, D.1
Banaschewski, T.2
-
17
-
-
67651121684
-
Candidate gene studies of ADHD: A meta-analytic review
-
Gizer IR, Ficks C, Waldman ID. Candidate gene studies of ADHD: a meta-analytic review. Hum Genet 2009;126:51-90.
-
(2009)
Hum Genet
, vol.126
, pp. 51-90
-
-
Gizer, I.R.1
Ficks, C.2
Waldman, I.D.3
-
18
-
-
61449155496
-
Genetics of dopamine receptors and drug addiction: A comprehensive review
-
Le Foll B, Gallo A, Le Strat Y, et al. Genetics of dopamine receptors and drug addiction: a comprehensive review. Behav Pharmacol 2009; 20:1-17.
-
(2009)
Behav Pharmacol
, vol.20
, pp. 1-17
-
-
le Foll, B.1
Gallo, A.2
le Strat, Y.3
-
19
-
-
0034723036
-
Polymorphisms in dopamine receptors: What do they tell us?
-
Wong AH, Buckle CE, Van Tol HH. Polymorphisms in dopamine receptors: What do they tell us? Eur J Pharmacol 2000;410:183-203.
-
(2000)
Eur J Pharmacol
, vol.410
, pp. 183-203
-
-
Wong, A.H.1
Buckle, C.E.2
van Tol, H.H.3
-
20
-
-
0037297443
-
Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders
-
author reply
-
Millar JK, Thomson PA, Wray NR, et al. Response to Amar J. Klar: The chromosome 1;11 translocation provides the best evidence supporting genetic etiology for schizophrenia and bipolar affective disorders. Genetics 2003;163:833-5, author reply 837-8.
-
(2003)
Genetics
, vol.163
, pp. 833-835
-
-
Millar, J.K.1
Thomson, P.A.2
Wray, N.R.3
-
21
-
-
3442888075
-
The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations
-
Hall D, Gogos JA, Karayiorgou M. The contribution of three strong candidate schizophrenia susceptibility genes in demographically distinct populations. Genes Brain Behav 2004;3:240-8.
-
(2004)
Genes Brain Behav
, vol.3
, pp. 240-248
-
-
Hall, D.1
Gogos, J.A.2
Karayiorgou, M.3
-
23
-
-
0019026208
-
Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase
-
Embi N, Rylatt DB, Cohen P. Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase. Eur J Biochem 1980; 107: 519-27.
-
(1980)
Eur J Biochem
, vol.107
, pp. 519-527
-
-
Embi, N.1
Rylatt, D.B.2
Cohen, P.3
-
24
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi DR, Andjelkovic M, Caudwell B, et al. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 1996; 15: 6541-51.
-
(1996)
EMBO J
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
-
25
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, et al. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378:785-9.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
-
26
-
-
1542570268
-
Physiological roles of glycogen synthase kinase-3: Potential as a therapeutic target for diabetes and other disorders
-
Woodgett JR. Physiological roles of glycogen synthase kinase-3: potential as a therapeutic target for diabetes and other disorders. Curr Drug Targets Immune Endocr Metabol Disord 2003;3:281-90.
-
(2003)
Curr Drug Targets Immune Endocr Metabol Disord
, vol.3
, pp. 281-290
-
-
Woodgett, J.R.1
-
27
-
-
3042635178
-
GSK3 inhibitors: Development and therapeutic potential
-
Cohen P, Goedert M. GSK3 inhibitors: development and therapeutic potential. Nat Rev Drug Discov 2004;3:479-87.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 479-487
-
-
Cohen, P.1
Goedert, M.2
-
29
-
-
57649239938
-
Decoding the epigenetic language of neuronal plasticity
-
Borrelli E, Nestler EJ, Allis CD, et al. Decoding the epigenetic language of neuronal plasticity. Neuron 2008;60:961-74.
-
(2008)
Neuron
, vol.60
, pp. 961-974
-
-
Borrelli, E.1
Nestler, E.J.2
Allis, C.D.3
-
30
-
-
0035489468
-
PKB/AKT: Functional insights from gen - etic models
-
Scheid MP, Woodgett JR. PKB/AKT: functional insights from gen - etic models. Nat Rev Mol Cell Biol 2001;2:760-8.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 760-768
-
-
Scheid, M.P.1
Woodgett, J.R.2
-
31
-
-
22744449073
-
An Akt/beta-Arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior
-
Beaulieu JM, Sotnikova TD, Marion S, et al. An Akt/beta-Arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 2005;122:261-73.
-
(2005)
Cell
, vol.122
, pp. 261-273
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Marion, S.3
-
32
-
-
0029942186
-
Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
-
Andjelkovi M, Jakubowicz T, Cron P, et al. Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. Proc Natl Acad Sci U S A 1996;93:5699-704.
-
(1996)
Roc Natl Acad Sci U S A
, vol.93
, pp. 5699-5704
-
-
Andjelkovi, M.1
Jakubowicz, T.2
Cron, P.3
-
33
-
-
4544314719
-
Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein Kinase B) activity in 3T3-L1 adipocytes
-
Ugi S, Imamura T, Maegawa H, et al. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein Kinase B) activity in 3T3-L1 adipocytes. Mol Cell Biol 2004;24:8778-89.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8778-8789
-
-
Ugi, S.1
Imamura, T.2
Maegawa, H.3
-
34
-
-
0035909112
-
Judging a protein by more than its name: GSK-3
-
2001:re12
-
Woodgett JR. Judging a protein by more than its name: GSK-3. Sci STKE 2001;2001:re12.
-
(2001)
Sci STKE
-
-
Woodgett, J.R.1
-
35
-
-
0027960448
-
Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
-
Stambolic V, Woodgett JR. Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation. Biochem J 1994;303:701-4.
-
(1994)
Biochem J
, vol.303
, pp. 701-704
-
-
Stambolic, V.1
Woodgett, J.R.2
-
36
-
-
0018378511
-
Multiple receptors for dopamine
-
Kebabian JW, Calne DB. Multiple receptors for dopamine. Nature 1979;277:93-6.
-
(1979)
Nature
, vol.277
, pp. 93-96
-
-
Kebabian, J.W.1
Calne, D.B.2
-
37
-
-
0015238826
-
Dopamine-sensitive adenyl cyclase: Possible role in synaptic transmission
-
Kebabian JW, Greengard P. Dopamine-sensitive adenyl cyclase: possible role in synaptic transmission. Science 1971;174:1346-9.
-
(1971)
Science
, vol.174
, pp. 1346-1349
-
-
Kebabian, J.W.1
Greengard, P.2
-
38
-
-
0020645475
-
Pharmacological characterization of the D2 dopamine receptor negatively coupled with adenylate cyclase in rat anterior pituitary
-
Enjalbert A, Bockaert J. Pharmacological characterization of the D2 dopamine receptor negatively coupled with adenylate cyclase in rat anterior pituitary. Mol Pharmacol 1983;23:576-84.
-
(1983)
Mol Pharmacol
, vol.23
, pp. 576-584
-
-
Enjalbert, A.1
Bockaert, J.2
-
39
-
-
6844250767
-
Dopamine receptors: From structure to function
-
Missale C, Nash SR, Robinson SW, et al. Dopamine receptors: from structure to function. Physiol Rev 1998;78:189-225.
-
(1998)
Physiol Rev
, vol.78
, pp. 189-225
-
-
Missale, C.1
Nash, S.R.2
Robinson, S.W.3
-
40
-
-
78449246412
-
The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: Increased high affinity state following amphetamine and in schizophrenia
-
Perreault ML, Hasbi A, Alijaniaram M, et al. The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia. J Biol Chem 2010.
-
(2010)
J Biol Chem
-
-
Perreault, M.L.1
Hasbi, A.2
Alijaniaram, M.3
-
41
-
-
33846328669
-
D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum
-
Rashid AJ, So CH, Kong MM, et al. D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum. Proc Natl Acad Sci U S A 2007; 104: 654-9.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 654-659
-
-
Rashid, A.J.1
So, C.H.2
Kong, M.M.3
-
42
-
-
79952016655
-
Confocal analysis of cholinergic and dopaminergic inputs onto pyramidal cells in the prefrontal cortex of rodents
-
Zhang ZW, Burke MW, Calakos N, et al. Confocal analysis of cholinergic and dopaminergic inputs onto pyramidal cells in the prefrontal cortex of rodents. Front Neuroanat 2010;4:21.
-
(2010)
Front Neuroanat
, vol.4
, pp. 21
-
-
Zhang, Z.W.1
Burke, M.W.2
Calakos, N.3
-
43
-
-
40849085572
-
Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia
-
Shuen JA, Chen M, Gloss B, et al. Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia. J Neurosci 2008; 28:2681-5.
-
(2008)
J Neurosci
, vol.28
, pp. 2681-2685
-
-
Shuen, J.A.1
Chen, M.2
Gloss, B.3
-
44
-
-
70349232427
-
Looking BAC at striatal signaling: Cell-specific analysis in new transgenic mice
-
Valjent E, Bertran-Gonzalez J, Herve D, et al. Looking BAC at striatal signaling: cell-specific analysis in new transgenic mice. Trends Neurosci 2009;32:538-47.
-
(2009)
Trends Neurosci
, vol.32
, pp. 538-547
-
-
Valjent, E.1
Bertran-Gonzalez, J.2
Herve, D.3
-
45
-
-
48149108931
-
Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
-
Bateup HS, Svenningsson P, Kuroiwa M, et al. Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs. Nat Neurosci 2008;11:932-9.
-
(2008)
Nat Neurosci
, vol.11
, pp. 932-939
-
-
Bateup, H.S.1
Svenningsson, P.2
Kuroiwa, M.3
-
46
-
-
1842787936
-
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
-
Beaulieu JM, Sotnikova TD, Yao WD, et al. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc Natl Acad Sci U S A 2004; 101: 5099-104.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 5099-5104
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Yao, W.D.3
-
47
-
-
33751178666
-
Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice
-
Beaulieu JM, Sotnikova TD, Gainetdinov RR, et al. Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice. J Biol Chem 2006;281:32072-80.
-
(2006)
J Biol Chem
, vol.281
, pp. 32072-32080
-
-
Beaulieu, J.M.1
Sotnikova, T.D.2
Gainetdinov, R.R.3
-
48
-
-
33846136445
-
Dual alteration of limbic dopamine D1 receptor-mediated signalling and the Akt/GSK3 pathway in dopamine D3 receptor mutants during the development of methamphetamine sensitization
-
Chen PC, Lao CL, Chen JC. Dual alteration of limbic dopamine D1 receptor-mediated signalling and the Akt/GSK3 pathway in dopamine D3 receptor mutants during the development of methamphetamine sensitization. J Neurochem 2007;100:225-41.
-
(2007)
J Neurochem
, vol.100
, pp. 225-241
-
-
Chen, P.C.1
Lao, C.L.2
Chen, J.C.3
-
49
-
-
34447295080
-
Dopamine depletion and subsequent treatment with L-DOPA, but not the long-lived dopamine agonist pergolide, enhances activity of the Akt pathway in the rat striatum
-
Bychkov E, Ahmed MR, Dalby KN, et al. Dopamine depletion and subsequent treatment with L-DOPA, but not the long-lived dopamine agonist pergolide, enhances activity of the Akt pathway in the rat striatum. J Neurochem 2007;102:699-711.
-
(2007)
J Neurochem
, vol.102
, pp. 699-711
-
-
Bychkov, E.1
Ahmed, M.R.2
Dalby, K.N.3
-
50
-
-
0842310838
-
Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia
-
Emamian ES, Hall D, Birnbaum MJ, et al. Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nat Genet 2004; 36:131-7.
-
(2004)
Nat Genet
, vol.36
, pp. 131-137
-
-
Emamian, E.S.1
Hall, D.2
Birnbaum, M.J.3
-
51
-
-
34447115083
-
Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex
-
Roh MS, Seo MS, Kim Y, et al. Haloperidol and clozapine differentially regulate signals upstream of glycogen synthase kinase 3 in the rat frontal cortex. Exp Mol Med 2007;39:353-60.
-
(2007)
Exp Mol Med
, vol.39
, pp. 353-360
-
-
Roh, M.S.1
Seo, M.S.2
Kim, Y.3
-
52
-
-
33846604269
-
Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo
-
Beaulieu JM, Tirotta E, Sotnikova TD, et al. Regulation of Akt signaling by D2 and D3 dopamine receptors in vivo. J Neurosci 2007; 27: 881-5.
-
(2007)
J Neurosci
, vol.27
, pp. 881-885
-
-
Beaulieu, J.M.1
Tirotta, E.2
Sotnikova, T.D.3
-
53
-
-
0242721361
-
Multifaceted roles of beta-Arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
-
Shenoy SK, Lefkowitz RJ. Multifaceted roles of beta-Arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. Biochem J 2003;375:503-15.
-
(2003)
Biochem J
, vol.375
, pp. 503-515
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
54
-
-
1642292051
-
Desensitization of G protein-coupled receptors and neuronal functions
-
Gainetdinov RR, Premont RT, Bohn LM, et al. Desensitization of G protein-coupled receptors and neuronal functions. Annu Rev Neurosci 2004;27:107-44.
-
(2004)
Annu Rev Neurosci
, vol.27
, pp. 107-144
-
-
Gainetdinov, R.R.1
Premont, R.T.2
Bohn, L.M.3
-
55
-
-
0025352299
-
Beta-Arrestin: A protein that regulates beta-adrenergic receptor function
-
Lohse MJ, Benovic JL, Codina J, et al. Beta-Arrestin: a protein that regulates beta-adrenergic receptor function. Science 1990;248:1547-50.
-
(1990)
Science
, vol.248
, pp. 1547-1550
-
-
Lohse, M.J.1
Benovic, J.L.2
Codina, J.3
-
56
-
-
0030593035
-
Role of beta- Arrestin in mediating agonist-promoted G protein-coupled receptor internalization
-
Ferguson SS, Downey WE III, Colapietro AM, et al. Role of beta- Arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 1996;271:363-6.
-
(1996)
Science
, vol.271
, pp. 363-366
-
-
Ferguson, S.S.1
Downey III, W.E.2
Colapietro, A.M.3
-
57
-
-
0037088608
-
Beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: Identification of a beta-Arrestin binging site in beta 2-adaptin
-
Laporte SA, Miller WE, Kim KM, et al. Beta-Arrestin/AP-2 interaction in G protein-coupled receptor internalization: identification of a beta-Arrestin binging site in beta 2-adaptin. J Biol Chem 2002; 277: 9247-54.
-
(2002)
J Biol Chem
, vol.277
, pp. 9247-9254
-
-
Laporte, S.A.1
Miller, W.E.2
Kim, K.M.3
-
58
-
-
17644402459
-
Transduction of receptor signals by beta- Arrestins
-
Lefkowitz RJ, Shenoy SK. Transduction of receptor signals by beta- Arrestins. Science 2005;308:512-7.
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
59
-
-
0033613938
-
Beta-Arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
-
Luttrell LM, Ferguson SS, Daaka Y, et al. Beta-Arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science 1999;283:655-61.
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
Ferguson, S.S.2
Daaka, Y.3
-
60
-
-
0035956983
-
Activation and targeting of extracellular signal-regulated kinases by beta-Arrestin scaffolds
-
Luttrell LM, Roudabush FL, Choy EW, et al. Activation and targeting of extracellular signal-regulated kinases by beta-Arrestin scaffolds. Proc Natl Acad Sci U S A 2001;98:2449-54.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2449-2454
-
-
Luttrell, L.M.1
Roudabush, F.L.2
Choy, E.W.3
-
61
-
-
0033601341
-
Enhanced morphine analgesia in mice lacking beta-Arrestin 2
-
Bohn LM, Lefkowitz RJ, Gainetdinov RR, et al. Enhanced morphine analgesia in mice lacking beta-Arrestin 2. Science 1999; 286: 2495-8.
-
(1999)
Science
, vol.286
, pp. 2495-2498
-
-
Bohn, L.M.1
Lefkowitz, R.J.2
Gainetdinov, R.R.3
-
62
-
-
0033555898
-
Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity
-
Gainetdinov RR, Wetsel WC, Jones SR, et al. Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 1999;283:397-401.
-
(1999)
Science
, vol.283
, pp. 397-401
-
-
Gainetdinov, R.R.1
Wetsel, W.C.2
Jones, S.R.3
-
63
-
-
37649023273
-
A beta-Arrestin 2 signaling complex mediates lithium action on behavior
-
Beaulieu JM, Marion S, Rodriguiz RM, et al. A beta-Arrestin 2 signaling complex mediates lithium action on behavior. Cell 2008; 132: 125-36.
-
(2008)
Cell
, vol.132
, pp. 125-136
-
-
Beaulieu, J.M.1
Marion, S.2
Rodriguiz, R.M.3
-
64
-
-
0344824657
-
Enhanced rewarding properties of morphine, but not cocaine, in beta(Arrestin)-2 knock-out mice
-
Bohn LM, Gainetdinov RR, Sotnikova TD, et al. Enhanced rewarding properties of morphine, but not cocaine, in beta(Arrestin)-2 knock-out mice. J Neurosci 2003;23:10265-73.
-
(2003)
J Neurosci
, vol.23
, pp. 10265-10273
-
-
Bohn, L.M.1
Gainetdinov, R.R.2
Sotnikova, T.D.3
-
65
-
-
0029588435
-
Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic
-
Zhou QY, Palmiter RD. Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic. Cell 1995;83:1197-209.
-
(1995)
Cell
, vol.83
, pp. 1197-1209
-
-
Zhou, Q.Y.1
Palmiter, R.D.2
-
66
-
-
23944502329
-
Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease
-
Sotnikova TD, Beaulieu JM, Barak LS, et al. Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease. PLoS Biol 2005;3:e271.
-
(2005)
PLoS Biol
, vol.3
-
-
Sotnikova, T.D.1
Beaulieu, J.M.2
Barak, L.S.3
-
67
-
-
10644255687
-
AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
-
Gould TD, Einat H, Bhat R, et al. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int J Neuropsychopharmacol 2004;7:387-90.
-
(2004)
Int J Neuropsychopharmacol
, vol.7
, pp. 387-390
-
-
Gould, T.D.1
Einat, H.2
Bhat, R.3
-
68
-
-
80052964809
-
Evidence for antimanic efficacy of glycogen synthase kinase-3 (GSK3) inhibitors in a strain-specific model of acute mania
-
Jan 6, [Epub ahead of print]
-
Kalinichev M, Dawson LA. Evidence for antimanic efficacy of glycogen synthase kinase-3 (GSK3) inhibitors in a strain-specific model of acute mania. Int J Neuropsychopharmacol 2011 Jan 6:1-17. [Epub ahead of print].
-
(2011)
Int J Neuropsychopharmacol
, pp. 1-17
-
-
Kalinichev, M.1
Dawson, L.A.2
-
69
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich KP, Luo J, Rubie EA, et al. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 2000;406:86-90.
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
-
70
-
-
77953596703
-
Deficiency in the inhibitory serine- phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances
-
Polter A, Beurel E, Yang S, et al. Deficiency in the inhibitory serine- phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances. Neuropsychopharmacology 2010;35: 1761-74.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 1761-1774
-
-
Polter, A.1
Beurel, E.2
Yang, S.3
-
71
-
-
33748280959
-
Transgenic mice overexpressing glycogen synthase kinase 3beta: A putative model of hyperactivity and mania
-
Prickaerts J, Moechars D, Cryns K, et al. Transgenic mice overexpressing glycogen synthase kinase 3beta: a putative model of hyperactivity and mania. J Neurosci 2006;26:9022-9.
-
(2006)
J Neurosci
, vol.26
, pp. 9022-9029
-
-
Prickaerts, J.1
Moechars, D.2
Cryns, K.3
-
72
-
-
67049136336
-
Overview of animal models of schizophrenia
-
Chapter 9:Unit
-
Powell SB, Geyer MA. Overview of animal models of schizophrenia. Curr Protoc Neurosci 2007;Chapter 9:Unit 9.24.
-
(2007)
Curr Protoc Neurosci
, vol.9
, pp. 24
-
-
Powell, S.B.1
Geyer, M.A.2
-
73
-
-
0023161081
-
Perspectives on the discovery of central monoaminergic neurotransmission
-
Carlsson A. Perspectives on the discovery of central monoaminergic neurotransmission. Annu Rev Neurosci 1987;10:19-40.
-
(1987)
Annu Rev Neurosci
, vol.10
, pp. 19-40
-
-
Carlsson, A.1
-
74
-
-
21544433803
-
Serotonin modulates circadian entrainment in Drosophila
-
Yuan Q, Lin F, Zheng X, et al. Serotonin modulates circadian entrainment in Drosophila. Neuron 2005;47:115-27.
-
(2005)
Neuron
, vol.47
, pp. 115-127
-
-
Yuan, Q.1
Lin, F.2
Zheng, X.3
-
75
-
-
33846283059
-
Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics
-
Li X, Rosborough KM, Friedman AB, et al. Regulation of mouse brain glycogen synthase kinase-3 by atypical antipsychotics. Int J Neuropsychopharmacol 2007;10:7-19.
-
(2007)
Int J Neuropsychopharmacol
, vol.10
, pp. 7-19
-
-
Li, X.1
Rosborough, K.M.2
Friedman, A.B.3
-
76
-
-
3242761438
-
In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain
-
Li X, Zhu W, Roh MS, et al. In vivo regulation of glycogen synthase kinase-3beta (GSK3beta) by serotonergic activity in mouse brain. Neuropsychopharmacology 2004;29:1426-31.
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1426-1431
-
-
Li, X.1
Zhu, W.2
Roh, M.S.3
-
77
-
-
33846279370
-
Not only lithium: Regulation of glycogen synthase kinase-3 by antipsychotics and serotonergic drugs
-
Beaulieu JM. Not only lithium: regulation of glycogen synthase kinase-3 by antipsychotics and serotonergic drugs. Int J Neuropsychopharmacol 2007;10:3-6.
-
(2007)
Int J Neuropsychopharmacol
, vol.10
, pp. 3-6
-
-
Beaulieu, J.M.1
-
78
-
-
11344282078
-
Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression
-
Zhang X, Gainetdinov RR, Beaulieu JM, et al. Loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 2005;45:11-6.
-
(2005)
Neuron
, vol.45
, pp. 11-16
-
-
Zhang, X.1
Gainetdinov, R.R.2
Beaulieu, J.M.3
-
79
-
-
39549108481
-
Role of GSK3beta in behavioral abnormalities induced by serotonin deficiency
-
Beaulieu JM, Zhang X, Rodriguiz RM, et al. Role of GSK3beta in behavioral abnormalities induced by serotonin deficiency. Proc Natl Acad Sci U S A 2008;105:1333-8.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 1333-1338
-
-
Beaulieu, J.M.1
Zhang, X.2
Rodriguiz, R.M.3
-
80
-
-
57849145582
-
Forkhead box, class O transcription factors in brain: Regulation and behavioral manifestation
-
Polter A, Yang S, Zmijewska AA, et al. Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation. Biol Psychiatry 2009;65:150-9.
-
(2009)
Biol Psychiatry
, vol.65
, pp. 150-159
-
-
Polter, A.1
Yang, S.2
Zmijewska, A.A.3
-
81
-
-
33749076673
-
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity
-
Jacinto E, Facchinetti V, Liu D, et al. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell 2006;127:125-37.
-
(2006)
Cell
, vol.127
, pp. 125-137
-
-
Jacinto, E.1
Facchinetti, V.2
Liu, D.3
-
82
-
-
3342955475
-
Glycogen synthase kinase- 3beta haploinsufficiency mimics the behavioral and molecular effects of lithium
-
O'Brien WT, Harper AD, Jove F, et al. Glycogen synthase kinase- 3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J Neurosci 2004;24:6791-8.
-
(2004)
J Neurosci
, vol.24
, pp. 6791-6798
-
-
O'Brien, W.T.1
Harper, A.D.2
Jove, F.3
-
83
-
-
44449168264
-
Reply to Belmaker et al: GSK3β haploinsufficiency results in lithium-like effects in the forced swim test
-
Beaulieu JM, Zhang X, Rodriguiz RM, et al. Reply to Belmaker et al: GSK3β haploinsufficiency results in lithium-like effects in the forced swim test. Proc Natl Acad Sci U S A 2008;105:E24.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
-
-
Beaulieu, J.M.1
Zhang, X.2
Rodriguiz, R.M.3
-
84
-
-
77952970457
-
Hyperactivity and enhanced curiosity of mice expressing PKB/SGK-resistant glycogen synthase kinase-3 (GSK-3)
-
Ackermann TF, Kempe DS, Lang F, et al. Hyperactivity and enhanced curiosity of mice expressing PKB/SGK-resistant glycogen synthase kinase-3 (GSK-3). Cell Physiol Biochem 2010;25:775-86.
-
(2010)
Cell Physiol Biochem
, vol.25
, pp. 775-786
-
-
Ackermann, T.F.1
Kempe, D.S.2
Lang, F.3
-
86
-
-
14644389398
-
Antipsychotics alter the protein expression levels of beta-catenin and GSK-3 in the rat medial prefrontal cortex and striatum
-
Alimohamad H, Rajakumar N, Seah YH, et al. Antipsychotics alter the protein expression levels of beta-catenin and GSK-3 in the rat medial prefrontal cortex and striatum. Biol Psychiatry 2005;57:533-42.
-
(2005)
Biol Psychiatry
, vol.57
, pp. 533-542
-
-
Alimohamad, H.1
Rajakumar, N.2
Seah, Y.H.3
-
87
-
-
51649084026
-
Antagonism of dopamine D2 receptor/beta-Arrestin 2 interaction is a common property of clinically effective antipsychotics
-
Masri B, Salahpour A, Didriksen M, et al. Antagonism of dopamine D2 receptor/beta-Arrestin 2 interaction is a common property of clinically effective antipsychotics. Proc Natl Acad Sci U S A 2008; 105:13656-61.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13656-13661
-
-
Masri, B.1
Salahpour, A.2
Didriksen, M.3
-
88
-
-
34250179171
-
Activation of the canon - ical Wnt pathway by the antipsychotics haloperidol and clozapine involves dishevelled-3
-
Sutton LP, Honardoust D, Mouyal J, et al. Activation of the canon - ical Wnt pathway by the antipsychotics haloperidol and clozapine involves dishevelled-3. J Neurochem 2007;102:153-69.
-
(2007)
J Neurochem
, vol.102
, pp. 153-169
-
-
Sutton, L.P.1
Honardoust, D.2
Mouyal, J.3
-
89
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein PS, Melton DA. A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A 1996;93:8455-9.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
90
-
-
0030449964
-
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
-
Stambolic V, Ruel L, Woodgett JR. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr Biol 1996;6:1664-8.
-
(1996)
Curr Biol
, vol.6
, pp. 1664-1668
-
-
Stambolic, V.1
Ruel, L.2
Woodgett, J.R.3
-
91
-
-
56649097561
-
Looking at lithium: Molecular moods and complex behaviour
-
Beaulieu JM, Caron MG. Looking at lithium: molecular moods and complex behaviour. Mol Interv 2008;8:230-41.
-
(2008)
Mol Interv
, vol.8
, pp. 230-241
-
-
Beaulieu, J.M.1
Caron, M.G.2
-
92
-
-
0036909443
-
Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium
-
De Sarno P, Li X, Jope RS. Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium. Neuropharmacology 2002;43:1158-64.
-
(2002)
Neuropharmacology
, vol.43
, pp. 1158-1164
-
-
de Sarno, P.1
Li, X.2
Jope, R.S.3
-
93
-
-
0016256059
-
Lithium and magnesium-dependent enzymes [letter]
-
Birch NJ. Lithium and magnesium-dependent enzymes [letter]. Lancet 1974;2:965-6.
-
(1974)
Lancet
, vol.2
, pp. 965-966
-
-
Birch, N.J.1
-
94
-
-
0034805180
-
Lithium inhibits glycogen synthase kinase-3 by competition for magnesium
-
Ryves WJ, Harwood AJ. Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem Biophys Res Commun 2001; 280:720-5.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 720-725
-
-
Ryves, W.J.1
Harwood, A.J.2
-
95
-
-
33750934403
-
Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning
-
Lai WS, Xu B, Westphal KG, et al. Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning. Proc Natl Acad Sci U S A 2006;103:16906-11.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16906-16911
-
-
Lai, W.S.1
Xu, B.2
Westphal, K.G.3
-
96
-
-
77950598371
-
Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action
-
Freyberg Z, Ferrando SJ, Javitch JA. Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug action. Am J Psychiatry 2010;167:388-96.
-
(2010)
Am J Psychiatry
, vol.167
, pp. 388-396
-
-
Freyberg, Z.1
Ferrando, S.J.2
Javitch, J.A.3
-
97
-
-
77954319396
-
Association of AKT1 gene variants and protein expression in both schizophrenia and bipolar disorder
-
Karege F, Perroud N, Schurhoff F, et al. Association of AKT1 gene variants and protein expression in both schizophrenia and bipolar disorder. Genes Brain Behav 2010;9:503-11.
-
(2010)
Genes Brain Behav
, vol.9
, pp. 503-511
-
-
Karege, F.1
Perroud, N.2
Schurhoff, F.3
-
98
-
-
77952978458
-
Association between AKT1 but not AKTIP genetic variants and increased risk for sui - cidal behavior in bipolar patients
-
Magno LA, Miranda DM, Neves FS, et al. Association between AKT1 but not AKTIP genetic variants and increased risk for sui - cidal behavior in bipolar patients. Genes Brain Behav 2010;9:411-8.
-
(2010)
Genes Brain Behav
, vol.9
, pp. 411-418
-
-
Magno, L.A.1
Miranda, D.M.2
Neves, F.S.3
-
99
-
-
4444350746
-
A glycogen synthase kinase 3-beta promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression
-
Benedetti F, Serretti A, Colombo C, et al. A glycogen synthase kinase 3-beta promoter gene single nucleotide polymorphism is associated with age at onset and response to total sleep deprivation in bipolar depression. Neurosci Lett 2004;368:123-6.
-
(2004)
Neurosci Lett
, vol.368
, pp. 123-126
-
-
Benedetti, F.1
Serretti, A.2
Colombo, C.3
-
100
-
-
33846095133
-
Alteration in kinase activity but not in protein levels of protein kinase B and glycogen synthase kinase-3beta in ventral prefrontal cortex of depressed suicide victims
-
Karege F, Perroud N, Burkhardt S, et al. Alteration in kinase activity but not in protein levels of protein kinase B and glycogen synthase kinase-3beta in ventral prefrontal cortex of depressed suicide victims. Biol Psychiatry 2007;61:240-5.
-
(2007)
Biol Psychiatry
, vol.61
, pp. 240-245
-
-
Karege, F.1
Perroud, N.2
Burkhardt, S.3
-
102
-
-
47749156793
-
The genetics of bipolar disorder: Genome 'hot regions,' genes, new potential candidates and future directions
-
Serretti A, Mandelli L. The genetics of bipolar disorder: genome 'hot regions,' genes, new potential candidates and future directions. Mol Psychiatry 2008;13:742-71.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 742-771
-
-
Serretti, A.1
Mandelli, L.2
-
103
-
-
78651334148
-
The relationship among neuregulin 1-stimulated phosphorylation of AKT, psychosis proneness, and habituation of arousal in nonclinical individuals
-
Keri S, Seres I, Kelemen O, et al. The relationship among neuregulin 1-stimulated phosphorylation of AKT, psychosis proneness, and habituation of arousal in nonclinical individuals. Schizophr Bull 2011;37:141-7.
-
(2011)
Schizophr Bull
, vol.37
, pp. 141-147
-
-
Keri, S.1
Seres, I.2
Kelemen, O.3
-
104
-
-
77950614376
-
Suppression of the P50 evoked response and neuregulin 1-induced AKT phosphorylation in firstepisode schizophrenia
-
Kéri S, Beniczky S, Kelemen O. Suppression of the P50 evoked response and neuregulin 1-induced AKT phosphorylation in firstepisode schizophrenia. Am J Psychiatry 2010;167:444-50.
-
(2010)
Am J Psychiatry
, vol.167
, pp. 444-450
-
-
Kéri, S.1
Beniczky, S.2
Kelemen, O.3
-
105
-
-
77956270438
-
Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1- ErbB signaling in cell models
-
Sei Y, Li Z, Song J, et al. Epistatic and functional interactions of catechol-o-methyltransferase (COMT) and AKT1 on neuregulin1- ErbB signaling in cell models. PLoS ONE 2010;5:e10789.
-
(2010)
PLoS ONE
, vol.5
-
-
Sei, Y.1
Li, Z.2
Song, J.3
-
106
-
-
33748055408
-
Impact of complex genetic variation in COMT on human brain function
-
Meyer-Lindenberg A, Nichols T, Callicott JH, et al. Impact of complex genetic variation in COMT on human brain function. Mol Psychiatry 2006;11:867-77, 797.
-
(2006)
Mol Psychiatry
, vol.11
, Issue.797
, pp. 867-877
-
-
Meyer-Lindenberg, A.1
Nichols, T.2
Callicott, J.H.3
-
107
-
-
78149459960
-
The dopamine metabolite 3-methoxytyramine is a neuromodulator
-
Sotnikova TD, Beaulieu JM, Espinoza S, et al. The dopamine metabolite 3-methoxytyramine is a neuromodulator. PLoS ONE 2010; 5:e13452.
-
(2010)
PLoS ONE
, vol.5
-
-
Sotnikova, T.D.1
Beaulieu, J.M.2
Espinoza, S.3
-
108
-
-
71849083984
-
Activation of glycogen synthase kinase-3 beta is required for hyperdopamine and D2 receptor-mediated in - hibition of synaptic NMDA receptor function in the rat prefrontal cortex
-
Li YC, Xi D, Roman J, et al. Activation of glycogen synthase kinase-3 beta is required for hyperdopamine and D2 receptor-mediated in - hibition of synaptic NMDA receptor function in the rat prefrontal cortex. J Neurosci 2009;29:15551-63.
-
(2009)
J Neurosci
, vol.29
, pp. 15551-15563
-
-
Li, Y.C.1
Xi, D.2
Roman, J.3
-
109
-
-
77955274106
-
Signaling pathways in schizophrenia: Emerging targets and therapeutic strategies
-
Karam CS, Ballon JS, Bivens NM, et al. Signaling pathways in schizophrenia: emerging targets and therapeutic strategies. Trends Pharmacol Sci 2010;31:381-90.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 381-390
-
-
Karam, C.S.1
Ballon, J.S.2
Bivens, N.M.3
-
110
-
-
77954904485
-
A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors
-
Du J, Wei Y, Liu L, et al. A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors. Proc Natl Acad Sci U S A 2010;107:11573-8.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11573-11578
-
-
Du, J.1
Wei, Y.2
Liu, L.3
-
111
-
-
0033588176
-
Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
-
Mohn AR, Gainetdinov RR, Caron MG, et al. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 1999;98:427-36.
-
(1999)
Cell
, vol.98
, pp. 427-436
-
-
Mohn, A.R.1
Gainetdinov, R.R.2
Caron, M.G.3
-
112
-
-
77955909841
-
mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists
-
Li N, Lee B, Liu RJ, et al. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 2010;329:959-64.
-
(2010)
Science
, vol.329
, pp. 959-964
-
-
Li, N.1
Lee, B.2
Liu, R.J.3
-
113
-
-
73149113991
-
Regulation of serotonin 1B receptor by glycogen synthase kinase-3
-
Chen L, Salinas GD, Li X. Regulation of serotonin 1B receptor by glycogen synthase kinase-3. Mol Pharmacol 2009;76:1150-61.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 1150-1161
-
-
Chen, L.1
Salinas, G.D.2
Li, X.3
-
114
-
-
79956309851
-
Glycogen synthase kinase-3beta is a functional modulator of serotonin 1B receptors
-
Chen L, Zhou W, Chen P, et al. Glycogen synthase kinase-3beta is a functional modulator of serotonin 1B receptors. Mol Pharmacol 2011; 79:974-86.
-
(2011)
Mol Pharmacol
, vol.79
, pp. 974-986
-
-
Chen, L.1
Zhou, W.2
Chen, P.3
-
115
-
-
78651312903
-
Is glycogen synthase kinase-3 a central modulator in mood regulation?
-
Li X, Jope RS. Is glycogen synthase kinase-3 a central modulator in mood regulation? Neuropsychopharmacology 2010;35:2143-54.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 2143-2154
-
-
Li, X.1
Jope, R.S.2
-
116
-
-
0019471639
-
Lithium induces rapid relief of depression in tricyclic antidepressant drug nonresponders
-
Dé Montigny C, Grunberg F, Mayer A, et al. Lithium induces rapid relief of depression in tricyclic antidepressant drug nonresponders. Br J Psychiatry 1981;138:252-6.
-
(1981)
Br J Psychiatry
, vol.138
, pp. 252-256
-
-
dé Montigny, C.1
Grunberg, F.2
Mayer, A.3
-
117
-
-
85047700549
-
What happened to lithium? Antidepressant augmentation in clinical settings
-
Valenstein M, McCarthy JF, Austin KL, et al. What happened to lithium? Antidepressant augmentation in clinical settings. Am J Psychiatry 2006;163:1219-25.
-
(2006)
Am J Psychiatry
, vol.163
, pp. 1219-1225
-
-
Valenstein, M.1
McCarthy, J.F.2
Austin, K.L.3
-
119
-
-
27744468952
-
Morphine-induced mu-opioid receptor internalization: A paradox solved in neurons
-
Beaulieu JM. Morphine-induced mu-opioid receptor internalization: a paradox solved in neurons. J Neurosci 2005;25:10061-3.
-
(2005)
J Neurosci
, vol.25
, pp. 10061-10063
-
-
Beaulieu, J.M.1
-
120
-
-
37449007716
-
The Drosoph Inf ServC locus in psychiatric illness
-
Chubb JE, Bradshaw NJ, Soares DC, et al. The Drosoph Inf ServC locus in psychiatric illness. Mol Psychiatry 2008;13:36-64.
-
(2008)
Mol Psychiatry
, vol.13
, pp. 36-64
-
-
Chubb, J.E.1
Bradshaw, N.J.2
Soares, D.C.3
-
121
-
-
0037435398
-
Analysis of a cluster of polymorphisms in AKT1 gene in bipolar pedigrees: A family-based association study
-
Toyota T, Yamada K, Detera-Wadleigh SD, et al. Analysis of a cluster of polymorphisms in AKT1 gene in bipolar pedigrees: a family-based association study. Neurosci Lett 2003;339:5-8.
-
(2003)
Neurosci Lett
, vol.339
, pp. 5-8
-
-
Toyota, T.1
Yamada, K.2
Detera-Wadleigh, S.D.3
-
122
-
-
0032693907
-
Genetic and non-genetic vulnerability factors in schizophrenia: The basis of the two hit hypothesis
-
Bayer TA, Falkai P, Maier W. Genetic and non-genetic vulnerability factors in schizophrenia: the basis of the "two hit hypothesis." J Psychiatr Res 1999;33:543-8.
-
(1999)
J Psychiatr Res
, vol.33
, pp. 543-548
-
-
Bayer, T.A.1
Falkai, P.2
Maier, W.3
-
123
-
-
0035183947
-
Neural development, cell-cell signaling, and the "two-hit" hypothesis of schizophrenia
-
Maynard TM, Sikich L, Lieberman JA, et al. Neural development, cell-cell signaling, and the "two-hit" hypothesis of schizophrenia. Schizophr Bull 2001;27:457-76.
-
(2001)
Schizophr Bull
, vol.27
, pp. 457-476
-
-
Maynard, T.M.1
Sikich, L.2
Lieberman, J.A.3
-
124
-
-
20844457467
-
Shared and specific sus cept - ibility loci for schizophrenia and bipolar disorder: A dense genome scan in Eastern Quebec families
-
Maziade M, Roy MA, Chagnon YC, et al. Shared and specific sus cept - ibility loci for schizophrenia and bipolar disorder: a dense genome scan in Eastern Quebec families. Mol Psychiatry 2005; 10: 486-99.
-
(2005)
Mol Psychiatry
, vol.10
, pp. 486-499
-
-
Maziade, M.1
Roy, M.A.2
Chagnon, Y.C.3
-
125
-
-
0015043748
-
Mutation and cancer: Statistical study of retino - blastoma
-
Knudson AG Jr. Mutation and cancer: statistical study of retino - blastoma. Proc Natl Acad Sci U S A 1971;68:820-3.
-
(1971)
Proc Natl Acad Sci U S A
, vol.68
, pp. 820-823
-
-
Knudson Jr, A.G.1
|