-
1
-
-
0036260697
-
Cellular response to oxidative stress: signalling for suicide and survival
-
Martindale J.L., Holbrook N.K. Cellular response to oxidative stress: signalling for suicide and survival. J. Cell. Physiol. 2002, 192:1-15.
-
(2002)
J. Cell. Physiol.
, vol.192
, pp. 1-15
-
-
Martindale, J.L.1
Holbrook, N.K.2
-
2
-
-
33749986298
-
Free radicals and antioxidant in normal physiological functions and human disease
-
Valko M., Leibfritz D., Moncol J., Cronin M.T.D., Mazur M., Tesler J. Free radicals and antioxidant in normal physiological functions and human disease. Int. J. Biochem. Cell Biol. 2007, 39:44-84.
-
(2007)
Int. J. Biochem. Cell Biol.
, vol.39
, pp. 44-84
-
-
Valko, M.1
Leibfritz, D.2
Moncol, J.3
Cronin, M.T.D.4
Mazur, M.5
Tesler, J.6
-
3
-
-
77951977494
-
Role of oxidatively induced DNA lesions in human pathogenesis
-
Sedelnikova O.A., Redon C.E., Dickey J.S., Nakamura A.J., Georgakilas A.G., Bonner W.M. Role of oxidatively induced DNA lesions in human pathogenesis. Mutat. Res. 2010, 704:152-159.
-
(2010)
Mutat. Res.
, vol.704
, pp. 152-159
-
-
Sedelnikova, O.A.1
Redon, C.E.2
Dickey, J.S.3
Nakamura, A.J.4
Georgakilas, A.G.5
Bonner, W.M.6
-
4
-
-
79956191022
-
Role of oxidative stress and DNA damage in human carcinogenesis
-
Kryston T.B., Georgiev A.B., Pissis P., Georgakilas A.G. Role of oxidative stress and DNA damage in human carcinogenesis. Mutat. Res. 2011, 711:193-201.
-
(2011)
Mutat. Res.
, vol.711
, pp. 193-201
-
-
Kryston, T.B.1
Georgiev, A.B.2
Pissis, P.3
Georgakilas, A.G.4
-
6
-
-
84867469576
-
Targeting DNA damage and repair: embracing the pharmacological era for successful cancer therapy
-
in press.
-
K. Aziz, S. Nowsheen, G. Pantelias, G. Iliakis, V. Gorgoulis, A.G. Georgakilas, Targeting DNA damage and repair: embracing the pharmacological era for successful cancer therapy, Pharmacol. Ther. (2011), in press.
-
(2011)
Pharmacol. Ther.
-
-
Aziz, K.1
Nowsheen, S.2
Pantelias, G.3
Iliakis, G.4
Gorgoulis, V.5
Georgakilas, A.G.6
-
7
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
Sablina A.A., Budanov A.V., Ilyinskaya G.V., Agapova L.S., Kravchenko J.E., Chumakov P.M. The antioxidant function of the p53 tumor suppressor. Nat. Med. 2005, 11:1306-1313.
-
(2005)
Nat. Med.
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
8
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak K., Xia Y., Zweier J.L., Kinzler K.W., Vogelstein B. A model for p53-induced apoptosis. Nature 1997, 389:300-305.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
9
-
-
30044442791
-
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes
-
Kimura K., Wakamatsu A., Suzuki Y., et al. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Genome Res. 2006, 16:55-65.
-
(2006)
Genome Res.
, vol.16
, pp. 55-65
-
-
Kimura, K.1
Wakamatsu, A.2
Suzuki, Y.3
-
10
-
-
0026556950
-
Identification and characterization of the enzymatic activity of zeta-crystallin from guinea PIG lens. A novel NADPH: quinine oxidoreductase
-
Rao P.V., Krishna C.M., Zigler J.S. Identification and characterization of the enzymatic activity of zeta-crystallin from guinea PIG lens. A novel NADPH: quinine oxidoreductase. J. Biol. Chem. 1992, 267:96-102.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 96-102
-
-
Rao, P.V.1
Krishna, C.M.2
Zigler, J.S.3
-
11
-
-
67650511713
-
Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinine oxidoreductase PIG3
-
Porté S., Valencia E., Yakovtseva E.A., Borràs E., Shafqat N., Debreczeny J.É., Pike A.C.W., Oppermann U., Farrés J., Fita I., Parés X. Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinine oxidoreductase PIG3. J. Biol. Chem. 2009, 284:17194-17205.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 17194-17205
-
-
Porté, S.1
Valencia, E.2
Yakovtseva, E.A.3
Borràs, E.4
Shafqat, N.5
Debreczeny, J.É.6
Pike, A.C.W.7
Oppermann, U.8
Farrés, J.9
Fita, I.10
Parés, X.11
-
12
-
-
0026849821
-
Definition of a consensus binding site for p53
-
El-Deiry W.S., Kern S.E., Pietenpol J.A., Kinzler K.W., Vogelstein B. Definition of a consensus binding site for p53. Nat. Genet. 1992, 1:45-49.
-
(1992)
Nat. Genet.
, vol.1
, pp. 45-49
-
-
El-Deiry, W.S.1
Kern, S.E.2
Pietenpol, J.A.3
Kinzler, K.W.4
Vogelstein, B.5
-
13
-
-
0032541325
-
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression
-
Venot C., Maratrat M., Dureuil C., Conseiller E., Bracco L., Debussche L. The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression. EMBO J. 1998, 17:4668-4679.
-
(1998)
EMBO J.
, vol.17
, pp. 4668-4679
-
-
Venot, C.1
Maratrat, M.2
Dureuil, C.3
Conseiller, E.4
Bracco, L.5
Debussche, L.6
-
14
-
-
0036510121
-
A polymorphic microsatellite that mediates induction of PIG3 by p53
-
Contente A., Dittmer A., Koch M.C., Roth J., Dobbelstein M. A polymorphic microsatellite that mediates induction of PIG3 by p53. Nat. Genet. 2002, 30:315-320.
-
(2002)
Nat. Genet.
, vol.30
, pp. 315-320
-
-
Contente, A.1
Dittmer, A.2
Koch, M.C.3
Roth, J.4
Dobbelstein, M.5
-
15
-
-
5644285664
-
Absence of association with cancer risk and low frequency of alterations at a p53 responsive PIG3 gene polymorphism in breast and lung carcinomas
-
Gorgoulis A.G., Liloglou T., Sigala F., Korkolis D., Yannoukakos D., Papalambros E., Asimacopoulos P.J., Papavassiliou A.G., Kotsinas A. Absence of association with cancer risk and low frequency of alterations at a p53 responsive PIG3 gene polymorphism in breast and lung carcinomas. Mutat. Res. 2004, 556:143-150.
-
(2004)
Mutat. Res.
, vol.556
, pp. 143-150
-
-
Gorgoulis, A.G.1
Liloglou, T.2
Sigala, F.3
Korkolis, D.4
Yannoukakos, D.5
Papalambros, E.6
Asimacopoulos, P.J.7
Papavassiliou, A.G.8
Kotsinas, A.9
-
16
-
-
33645163853
-
Association of the PIG3 promoter polymorphism with invasive bladder cancer in a Japanese population
-
Ito M., Nishiyama H., Watanabe J., Kawanishi H., Takahashi T., Kamoto T., Habuchi T., Ogawa O. Association of the PIG3 promoter polymorphism with invasive bladder cancer in a Japanese population. Jpn. J. Clin. Oncol. 2006, 36:116-120.
-
(2006)
Jpn. J. Clin. Oncol.
, vol.36
, pp. 116-120
-
-
Ito, M.1
Nishiyama, H.2
Watanabe, J.3
Kawanishi, H.4
Takahashi, T.5
Kamoto, T.6
Habuchi, T.7
Ogawa, O.8
-
17
-
-
0344406084
-
A promoter that acquired p53 responsiveness during primate evolution
-
Contente A., Zischler H., Einspanier A., Dobbelstein M. A promoter that acquired p53 responsiveness during primate evolution. Cancer Res. 2003, 63:1756-1758.
-
(2003)
Cancer Res.
, vol.63
, pp. 1756-1758
-
-
Contente, A.1
Zischler, H.2
Einspanier, A.3
Dobbelstein, M.4
-
18
-
-
0035870541
-
Additional characterization of a hexanucleotide polymorphic site in the first intron of human H-ras gene: comparative study of its alterations in non-small cell lung carcinomas and sporadic invasive breast carcinomas
-
Kotsinas A., Gorgoulis V.G., Zacharatos P., Mariatos G., Kokotas S., Liloglou T., Ikonomopoulos J., Zoumpourlis V., Kyroudi A., Field J.K., Asimacopoulos P.J., Kittas C. Additional characterization of a hexanucleotide polymorphic site in the first intron of human H-ras gene: comparative study of its alterations in non-small cell lung carcinomas and sporadic invasive breast carcinomas. Cancer Genet. Cytogenet. 2001, 126:147-154.
-
(2001)
Cancer Genet. Cytogenet.
, vol.126
, pp. 147-154
-
-
Kotsinas, A.1
Gorgoulis, V.G.2
Zacharatos, P.3
Mariatos, G.4
Kokotas, S.5
Liloglou, T.6
Ikonomopoulos, J.7
Zoumpourlis, V.8
Kyroudi, A.9
Field, J.K.10
Asimacopoulos, P.J.11
Kittas, C.12
-
19
-
-
46849115153
-
Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes
-
Xie P., Tian C., An L., Nie J., Lu K., Xing G., Zhang L., He F. Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes. Cell. Signal. 2008, 20:1671-1678.
-
(2008)
Cell. Signal.
, vol.20
, pp. 1671-1678
-
-
Xie, P.1
Tian, C.2
An, L.3
Nie, J.4
Lu, K.5
Xing, G.6
Zhang, L.7
He, F.8
-
20
-
-
0036261733
-
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets
-
MacLachlan T.K., Takimoto R., El-Deiry W.S. BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets. Mol. Cell. Biol. 2002, 22:4280-4292.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 4280-4292
-
-
MacLachlan, T.K.1
Takimoto, R.2
El-Deiry, W.S.3
-
21
-
-
34547956843
-
HCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes
-
Tanaka T., Ohkubo S., Tatsuno I., Prives C. hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes. Cell 2007, 130:638-650.
-
(2007)
Cell
, vol.130
, pp. 638-650
-
-
Tanaka, T.1
Ohkubo, S.2
Tatsuno, I.3
Prives, C.4
-
23
-
-
27144540980
-
Characterisation of a novel p53 down-regulated promoter in intron 3 of the human MDM2 oncogene
-
Liang H., Lunec J. Characterisation of a novel p53 down-regulated promoter in intron 3 of the human MDM2 oncogene. Gene 2005, 361:112-118.
-
(2005)
Gene
, vol.361
, pp. 112-118
-
-
Liang, H.1
Lunec, J.2
-
24
-
-
0346729917
-
Multiple response elements and differential p53 binding control Perp expression during apoptosis
-
Reczek E.E., Flores E.R., Tsay A.S., Attardi L.D., Jacks T. Multiple response elements and differential p53 binding control Perp expression during apoptosis. Mol. Cancer Res. 2003, 1:1048-1057.
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 1048-1057
-
-
Reczek, E.E.1
Flores, E.R.2
Tsay, A.S.3
Attardi, L.D.4
Jacks, T.5
-
25
-
-
2642550761
-
UV-dependent alternative splicing uncouples p53 activity and PIG3 gene function through rapid proteolytic degradation
-
Nicholls C.D., Shields M.A., Lee P.W., Robbins S.M., Beattie T.L. UV-dependent alternative splicing uncouples p53 activity and PIG3 gene function through rapid proteolytic degradation. J. Biol. Chem. 2004, 279:24171-24178.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24171-24178
-
-
Nicholls, C.D.1
Shields, M.A.2
Lee, P.W.3
Robbins, S.M.4
Beattie, T.L.5
-
26
-
-
77956928317
-
Why is p53-inducible gene 3 rarely affected in cancer?
-
Kotsinas A., Pateras I.S., Galanos P.S., Karamouzis M.V., Sfikakis P.P., Gorgoulis V.G. Why is p53-inducible gene 3 rarely affected in cancer?. Oncogene 2010, 29:5220.
-
(2010)
Oncogene
, vol.29
, pp. 5220
-
-
Kotsinas, A.1
Pateras, I.S.2
Galanos, P.S.3
Karamouzis, M.V.4
Sfikakis, P.P.5
Gorgoulis, V.G.6
-
27
-
-
56149117047
-
Multiple factors influence the normal and UV-inducible alternative splicing of PIG3
-
Nicholl C.D., Beattie T.L. Multiple factors influence the normal and UV-inducible alternative splicing of PIG3. Biochim. Biophys. Acta 2008, 1779:838-849.
-
(2008)
Biochim. Biophys. Acta
, vol.1779
, pp. 838-849
-
-
Nicholl, C.D.1
Beattie, T.L.2
-
28
-
-
65249124123
-
Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes
-
Amano T., Nakamizo A., Mishra S.K., Gumin J., Shinojima N., Sawaya R., Lang F.F. Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes. J. Neurooncol. 2009, 92:357-371.
-
(2009)
J. Neurooncol.
, vol.92
, pp. 357-371
-
-
Amano, T.1
Nakamizo, A.2
Mishra, S.K.3
Gumin, J.4
Shinojima, N.5
Sawaya, R.6
Lang, F.F.7
-
29
-
-
9144266953
-
Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors
-
Terui T., Murakami K., Takimoto R., et al. Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors. Cancer Res. 2003, 63:8948-8954.
-
(2003)
Cancer Res.
, vol.63
, pp. 8948-8954
-
-
Terui, T.1
Murakami, K.2
Takimoto, R.3
-
30
-
-
0034256962
-
P53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest
-
Flatt P.M., Polyak K., Tang L.J., Scatena C.D., Westfall M.D., Rubinstein L.A., Yu J., Kinzler K.W., Vogelstein B., Hill D.E., Pietenpol J. p53-dependent expression of PIG3 during proliferation, genotoxic stress, and reversible growth arrest. Cancer Lett. 2000, 156:63-72.
-
(2000)
Cancer Lett.
, vol.156
, pp. 63-72
-
-
Flatt, P.M.1
Polyak, K.2
Tang, L.J.3
Scatena, C.D.4
Westfall, M.D.5
Rubinstein, L.A.6
Yu, J.7
Kinzler, K.W.8
Vogelstein, B.9
Hill, D.E.10
Pietenpol, J.11
-
31
-
-
0035028599
-
Kinetics of p53 binding to promoter sites in vivo
-
Szak S.T., Mays D., Pietenpol J.A. Kinetics of p53 binding to promoter sites in vivo. Mol. Cell. Biol. 2002, 21:3375-3386.
-
(2002)
Mol. Cell. Biol.
, vol.21
, pp. 3375-3386
-
-
Szak, S.T.1
Mays, D.2
Pietenpol, J.A.3
-
33
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis T., Gorgoulis V.G., Bartek J. An oncogene-induced DNA damage model for cancer development. Science 2008, 319:1352-1355.
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.1
Gorgoulis, V.G.2
Bartek, J.3
-
34
-
-
0034732158
-
Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain
-
Roth J., Koch P., Contente A., Dobbelstein M. Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain. Oncogene 2000, 19:1834-1842.
-
(2000)
Oncogene
, vol.19
, pp. 1834-1842
-
-
Roth, J.1
Koch, P.2
Contente, A.3
Dobbelstein, M.4
-
35
-
-
1842536849
-
Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes
-
Willis A., Jung E.J., Wakefield T., Chen X. Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes. Oncogene 2004, 23:2330-2338.
-
(2004)
Oncogene
, vol.23
, pp. 2330-2338
-
-
Willis, A.1
Jung, E.J.2
Wakefield, T.3
Chen, X.4
-
36
-
-
3543103274
-
Constitutive and DNA damage inducible activation of PIG3 and MDM2 genes by tumor-derived p53 mutant C277Y
-
Pospisilova S., Siligan C., Ban J., Jug G., Kovar H. Constitutive and DNA damage inducible activation of PIG3 and MDM2 genes by tumor-derived p53 mutant C277Y. Mol. Cancer Res. 2004, 2:296-304.
-
(2004)
Mol. Cancer Res.
, vol.2
, pp. 296-304
-
-
Pospisilova, S.1
Siligan, C.2
Ban, J.3
Jug, G.4
Kovar, H.5
-
37
-
-
2942644738
-
Loss of heterozygosity of the polymorphic PIG3 microsatellite with low frequency in de novo acute leukemias
-
Nomdedéu J.F., Perea G., Estivill C., Lasa A., Brunet S., Avent́i{dotless}n A., Sierra J. Loss of heterozygosity of the polymorphic PIG3 microsatellite with low frequency in de novo acute leukemias. Leukemia 2004, 18:1148-1149.
-
(2004)
Leukemia
, vol.18
, pp. 1148-1149
-
-
Nomdedéu, J.F.1
Perea, G.2
Estivill, C.3
Lasa, A.4
Brunet, S.5
Avent́in, A.6
Sierra, J.7
-
38
-
-
36049039160
-
Microsatellite instability may involve the pentanucleotide repeat of the PIG3 promoter in bcr/abl acute lymphoblastic leukemia
-
Nomdedéu J.F., Perea G., Estivill C., Badell I., Lasa A., Aventín A. Microsatellite instability may involve the pentanucleotide repeat of the PIG3 promoter in bcr/abl acute lymphoblastic leukemia. Leuk. Res. 2008, 32:186-188.
-
(2008)
Leuk. Res.
, vol.32
, pp. 186-188
-
-
Nomdedéu, J.F.1
Perea, G.2
Estivill, C.3
Badell, I.4
Lasa, A.5
Aventín, A.6
-
39
-
-
46749114860
-
Uniparental disomy may be associated with microsatellite instability in acute myeloid leukemia (AML) with a normal karyotype
-
Serrano E., Carnicer M.J., Orantes V., Estivill C., Lasa A., Brunet S., Aventín A.M., Sierra J., Nomdedéu J.F. Uniparental disomy may be associated with microsatellite instability in acute myeloid leukemia (AML) with a normal karyotype. Leuk. Lymphoma 2008, 49:1178-1183.
-
(2008)
Leuk. Lymphoma
, vol.49
, pp. 1178-1183
-
-
Serrano, E.1
Carnicer, M.J.2
Orantes, V.3
Estivill, C.4
Lasa, A.5
Brunet, S.6
Aventín, A.M.7
Sierra, J.8
Nomdedéu, J.F.9
-
40
-
-
77954350283
-
A Large-scale genetic association study of esophageal adenocarcinoma risk
-
Liu C., Wu M.C., Chen F., Ter-Minassian M., Asomaning K., Zhai R., Wang Z., Su L., Heist R.S., Kulke M.H., Lin X., Liu G., Christiani D.C. A Large-scale genetic association study of esophageal adenocarcinoma risk. Carcinogenesis 2010, 31:1259-1263.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1259-1263
-
-
Liu, C.1
Wu, M.C.2
Chen, F.3
Ter-Minassian, M.4
Asomaning, K.5
Zhai, R.6
Wang, Z.7
Su, L.8
Heist, R.S.9
Kulke, M.H.10
Lin, X.11
Liu, G.12
Christiani, D.C.13
-
41
-
-
67749097763
-
Common genetic variants in candidate genes and risk of familial lymphoid malignancies
-
Liang X., Caporaso N., McMaster M.L., Ng D., Landgren O., Yeager M., Chanock S., Goldin L.R. Common genetic variants in candidate genes and risk of familial lymphoid malignancies. Br. J. Haematol. 2009, 146:418-423.
-
(2009)
Br. J. Haematol.
, vol.146
, pp. 418-423
-
-
Liang, X.1
Caporaso, N.2
McMaster, M.L.3
Ng, D.4
Landgren, O.5
Yeager, M.6
Chanock, S.7
Goldin, L.R.8
-
42
-
-
72149083027
-
Genetic susceptibility to distinct bladder cancer subphenotypes
-
Guey L.T., Garcia-Closas M., Murta-Nascimento C., et al. Genetic susceptibility to distinct bladder cancer subphenotypes. Eur. Urol. 2010, 57:283-292.
-
(2010)
Eur. Urol.
, vol.57
, pp. 283-292
-
-
Guey, L.T.1
Garcia-Closas, M.2
Murta-Nascimento, C.3
-
43
-
-
72449122919
-
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity
-
Hosgood H.D., Zhang L., Shen M., Berndt S.I., Vermeulen R., Li G., Yin S., Yeager M., Yuenger J., Rothman N., Chanock S., Smith M., Lan Q. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. Occup. Environ. Med. 2009, 66:848-853.
-
(2009)
Occup. Environ. Med.
, vol.66
, pp. 848-853
-
-
Hosgood, H.D.1
Zhang, L.2
Shen, M.3
Berndt, S.I.4
Vermeulen, R.5
Li, G.6
Yin, S.7
Yeager, M.8
Yuenger, J.9
Rothman, N.10
Chanock, S.11
Smith, M.12
Lan, Q.13
-
44
-
-
77949424949
-
The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage
-
Lee J.-H., Kang Y., Khare V., Jin Z.-Y., Kang M.-Y., Yoon Y., Hyun J.-W., Chung M.-H., Cho S.-I., Jun J.Y., Chang I.-Y., You H.J. The p53-inducible gene 3 (PIG3) contributes to early cellular response to DNA damage. Oncogene 2010, 29:1431-1450.
-
(2010)
Oncogene
, vol.29
, pp. 1431-1450
-
-
Lee, J.-H.1
Kang, Y.2
Khare, V.3
Jin, Z.-Y.4
Kang, M.-Y.5
Yoon, Y.6
Hyun, J.-W.7
Chung, M.-H.8
Cho, S.-I.9
Jun, J.Y.10
Chang, I.-Y.11
You, H.J.12
-
45
-
-
0034855105
-
Hypoxia and oxidative stress in breast cancer. Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer
-
Brown N.S., Bicknell R. Hypoxia and oxidative stress in breast cancer. Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer. Breast Cancer Res. 2001, 3:323-327.
-
(2001)
Breast Cancer Res.
, vol.3
, pp. 323-327
-
-
Brown, N.S.1
Bicknell, R.2
-
46
-
-
44449142812
-
Reactive oxygen species in tumor metastasis
-
Nishikawa M. Reactive oxygen species in tumor metastasis. Cancer Lett. 2008, 266:53-59.
-
(2008)
Cancer Lett.
, vol.266
, pp. 53-59
-
-
Nishikawa, M.1
-
47
-
-
34250357227
-
Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase
-
Higashitsuji H., Higashitsuji H., Masuda T., Liu Y., Itoh K., Fujita J. Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase. J. Biol. Chem. 2007, 282:13716-13725.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13716-13725
-
-
Higashitsuji, H.1
Higashitsuji, H.2
Masuda, T.3
Liu, Y.4
Itoh, K.5
Fujita, J.6
-
48
-
-
77955345506
-
Cellular apoptosis susceptibility (CSE1L/CAS) protein in cancer metastasis and chemotherapeutic drug induced apoptosis
-
Tai C.-J., Hsu C.-H., Shen S.-C., Lee W.-R., Jiang M.-C. Cellular apoptosis susceptibility (CSE1L/CAS) protein in cancer metastasis and chemotherapeutic drug induced apoptosis. J. Exp. Clin. Cancer Res. 2010, 29:110-118.
-
(2010)
J. Exp. Clin. Cancer Res.
, vol.29
, pp. 110-118
-
-
Tai, C.-J.1
Hsu, C.-H.2
Shen, S.-C.3
Lee, W.-R.4
Jiang, M.-C.5
-
49
-
-
42749088247
-
Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis
-
Zhang Q., Zhao X.H., Wang Z.J. Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis. Food Chem. Toxicol. 2008, 46:2042-2053.
-
(2008)
Food Chem. Toxicol.
, vol.46
, pp. 2042-2053
-
-
Zhang, Q.1
Zhao, X.H.2
Wang, Z.J.3
-
50
-
-
77958191599
-
ATM activation by oxidative stress
-
Guo Z., Kozlov S., Lavin M.F., Person M.D., Paull T.T. ATM activation by oxidative stress. Science 2010, 330:517-521.
-
(2010)
Science
, vol.330
, pp. 517-521
-
-
Guo, Z.1
Kozlov, S.2
Lavin, M.F.3
Person, M.D.4
Paull, T.T.5
-
51
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
Gorgoulis V.G., Vassiliou L.V., Karakaidos P., et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005, 434:907-913.
-
(2005)
Nature
, vol.434
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.V.2
Karakaidos, P.3
-
52
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
Bartkova J., Horejsí Z., Koed K., et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005, 434:864-870.
-
(2005)
Nature
, vol.434
, pp. 864-870
-
-
Bartkova, J.1
Horejsí, Z.2
Koed, K.3
-
53
-
-
33845235459
-
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
-
Bartkova J., Rezaei N., Liontos M., et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 2006, 444:633-637.
-
(2006)
Nature
, vol.444
, pp. 633-637
-
-
Bartkova, J.1
Rezaei, N.2
Liontos, M.3
-
54
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco R., Fumagalli M., Cicalese A., et al. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature 2006, 444:638-642.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
-
55
-
-
79959397953
-
Synthetic lethality: exploiting the addiction of cancer to DNA repair
-
Shaheen M., Allen C., Nickoloff J.A., Hromas R. Synthetic lethality: exploiting the addiction of cancer to DNA repair. Blood 2011, 117:6074-6082.
-
(2011)
Blood
, vol.117
, pp. 6074-6082
-
-
Shaheen, M.1
Allen, C.2
Nickoloff, J.A.3
Hromas, R.4
|